ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140030 modification-dependent protein binding 14/357 173/18639 0.0809248554913295 4.22509350561034 6.38848339300935e-06 0.00317323387302627 GO:0003712 transcription coregulator activity 25/357 495/18639 0.0505050505050505 2.63687293099058 1.12063947256616e-05 0.00317323387302627 GO:0001221 transcription coregulator binding 11/357 115/18639 0.0956521739130435 4.99400803799781 1.31306229228673e-05 0.00317323387302627 GO:0030695 GTPase regulator activity 24/357 489/18639 0.049079754601227 2.56245811207919 2.6745103614363e-05 0.00400738305899723 GO:0060589 nucleoside-triphosphatase regulator activity 24/357 490/18639 0.0489795918367347 2.55722860572801 2.76371245448085e-05 0.00400738305899723 GO:0051020 GTPase binding 18/357 315/18639 0.0571428571428571 2.98343337334934 3.99656656648749e-05 0.00482918460117238 GO:0005096 GTPase activator activity 16/357 271/18639 0.0590405904059041 3.0825141864864 7.27196261510333e-05 0.00753167556564273 GO:0045296 cadherin binding 18/357 334/18639 0.0538922155688623 2.81371710360791 8.49350183570001e-05 0.00769723603860314 GO:0031267 small GTPase binding 16/357 283/18639 0.0565371024734982 2.95180687115836 0.00012058867761299 0.00971408791882423 GO:0003779 actin binding 21/357 443/18639 0.0474040632054176 2.47497012348958 0.000138220558485995 0.0100209904902347 GO:0035064 methylated histone binding 7/357 74/18639 0.0945945945945946 4.93879173290938 0.000533608492628405 0.0349929674994054 GO:0003714 transcription corepressor activity 12/357 204/18639 0.0588235294117647 3.07118141374197 0.000590610643493754 0.0349929674994054 GO:0140034 methylation-dependent protein binding 7/357 76/18639 0.0921052631578947 4.80882352941176 0.00062746010688589 0.0349929674994054 GO:0019199 transmembrane receptor protein kinase activity 7/357 78/18639 0.0897435897435897 4.68552036199095 0.000733955476482344 0.0365659321193197 GO:0005131 growth hormone receptor binding 3/357 10/18639 0.3 15.663025210084 0.000756536526606614 0.0365659321193197 GO:0008013 beta-catenin binding 8/357 106/18639 0.0754716981132075 3.94038370065007 0.00098977523216051 0.0406765906304849 GO:0042393 histone binding 13/357 247/18639 0.0526315789473684 2.74789915966387 0.00100059035577505 0.0406765906304849 GO:0048185 activin binding 3/357 11/18639 0.272727272727273 14.2391138273491 0.00102551439302909 0.0406765906304849 GO:0017080 sodium channel regulator activity 5/357 41/18639 0.121951219512195 6.36708341873335 0.00106600720272995 0.0406765906304849 GO:0004842 ubiquitin-protein transferase activity 19/357 449/18639 0.0423162583518931 2.20933540454044 0.00112490520942146 0.0407778138415281 GO:0008200 ion channel inhibitor activity 5/357 43/18639 0.116279069767442 6.07094000390854 0.00132719143105515 0.044532165546166 GO:0008143 poly(A) binding 4/357 26/18639 0.153846153846154 8.03232062055592 0.00141737608331488 0.044532165546166 GO:0001223 transcription coactivator binding 5/357 44/18639 0.113636363636364 5.9329640947288 0.00147416823876963 0.044532165546166 GO:0016248 channel inhibitor activity 5/357 44/18639 0.113636363636364 5.9329640947288 0.00147416823876963 0.044532165546166 GO:0141110 transporter inhibitor activity 5/357 45/18639 0.111111111111111 5.80112044817927 0.00163278225831514 0.0473506854911391 GO:0070123 transforming growth factor beta receptor activity, type III 3/357 13/18639 0.230769230769231 12.0484809308339 0.0017276666869832 0.0481753210793393 GO:0019787 ubiquitin-like protein transferase activity 19/357 479/18639 0.0396659707724426 2.07096366730408 0.0023472785090126 0.0630287747790421 GO:0070566 adenylyltransferase activity 4/357 30/18639 0.133333333333333 6.96134453781513 0.00244645595466879 0.0633457345405311 GO:0120283 protein serine/threonine kinase binding 3/357 15/18639 0.2 10.4420168067227 0.00267156219018583 0.0667890547546459 GO:0070717 poly-purine tract binding 4/357 32/18639 0.125 6.52626050420168 0.0031151953242854 0.0734461316732773 GO:0005024 transforming growth factor beta receptor activity 3/357 16/18639 0.1875 9.78939075630252 0.00324176029454465 0.0734461316732773 GO:0005521 lamin binding 3/357 16/18639 0.1875 9.78939075630252 0.00324176029454465 0.0734461316732773 GO:0016755 aminoacyltransferase activity 19/357 496/18639 0.0383064516129032 1.99998305773922 0.00343972424817601 0.0755696993917456 GO:0140463 chromatin-protein adaptor activity 5/357 54/18639 0.0925925925925926 4.83426704014939 0.00367437025153534 0.0783505421283272 GO:0046332 SMAD binding 6/357 79/18639 0.0759493670886076 3.96532283799596 0.00406854910754458 0.0842770886562807 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/357 18/18639 0.166666666666667 8.70168067226891 0.004591759013224 0.0924729245718722 GO:0005496 steroid binding 7/357 108/18639 0.0648148148148148 3.38398692810458 0.00476355709666721 0.0933399701373979 GO:0004879 nuclear receptor activity 5/357 59/18639 0.0847457627118644 4.42458339267911 0.00538295740351366 0.100067797885831 GO:0070063 RNA polymerase binding 5/357 59/18639 0.0847457627118644 4.42458339267911 0.00538295740351366 0.100067797885831 GO:0098531 ligand-modulated transcription factor activity 5/357 60/18639 0.0833333333333333 4.35084033613445 0.00578214515170301 0.104801380874617 GO:0000339 RNA cap binding 3/357 20/18639 0.15 7.83151260504202 0.00623611481629218 0.110272761995411 GO:0019903 protein phosphatase binding 8/357 144/18639 0.0555555555555556 2.90056022408964 0.00662386681030876 0.114340558035092 GO:0051015 actin filament binding 10/357 209/18639 0.0478468899521531 2.49809014514897 0.00719743565249514 0.120767425882594 GO:0019208 phosphatase regulator activity 7/357 117/18639 0.0598290598290598 3.1236802413273 0.00732933343287469 0.120767425882594 GO:0019209 kinase activator activity 8/357 148/18639 0.0540540540540541 2.82216670451965 0.00776889299158926 0.125165498197827 GO:0035198 miRNA binding 4/357 42/18639 0.0952380952380952 4.97238895558223 0.00834965983701589 0.13020773478323 GO:0061630 ubiquitin protein ligase activity 14/357 353/18639 0.0396600566572238 2.07065489085152 0.00844105315146458 0.13020773478323 GO:0140033 acetylation-dependent protein binding 3/357 24/18639 0.125 6.52626050420168 0.0104648705610286 0.158063149098869 GO:0003713 transcription coactivator activity 11/357 256/18639 0.04296875 2.24340204831933 0.0106851415381704 0.158096481942317 GO:0019902 phosphatase binding 9/357 190/18639 0.0473684210526316 2.47310924369748 0.0111845931054699 0.162176600029313 GO:0031490 chromatin DNA binding 7/357 128/18639 0.0546875 2.85523897058824 0.0117081428882775 0.166439286156886 GO:0099106 ion channel regulator activity 8/357 160/18639 0.05 2.61050420168067 0.0121020488447039 0.168730488700199 GO:0061659 ubiquitin-like protein ligase activity 14/357 372/18639 0.0376344086021505 1.96489563567362 0.0129238070590328 0.175483001772051 GO:0005160 transforming growth factor beta receptor binding 3/357 26/18639 0.115384615384615 6.02424046541694 0.0130704580630217 0.175483001772051 GO:0005085 guanyl-nucleotide exchange factor activity 10/357 230/18639 0.0434782608695652 2.27000365363537 0.0135123212958621 0.178116962536364 GO:0001222 transcription corepressor binding 4/357 49/18639 0.0816326530612245 4.26204767621334 0.0142434159042973 0.182742199898973 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/357 10/18639 0.2 10.4420168067227 0.014871434198675 0.182742199898973 GO:0050815 phosphoserine residue binding 2/357 10/18639 0.2 10.4420168067227 0.014871434198675 0.182742199898973 GO:0070097 delta-catenin binding 2/357 10/18639 0.2 10.4420168067227 0.014871434198675 0.182742199898973 GO:0016247 channel regulator activity 8/357 168/18639 0.0476190476190476 2.48619447779112 0.0158409400904237 0.187252101600854 GO:0019838 growth factor binding 7/357 136/18639 0.0514705882352941 2.68728373702422 0.015905019816727 0.187252101600854 GO:0141052 histone H3 demethylase activity 3/357 28/18639 0.107142857142857 5.59393757503001 0.0160132831713834 0.187252101600854 GO:0141108 transporter regulator activity 8/357 170/18639 0.0470588235294118 2.45694513099357 0.0168933363319551 0.187579819949026 GO:0106222 lncRNA binding 3/357 29/18639 0.103448275862069 5.40104317589105 0.0176126192345708 0.187579819949026 GO:0030295 protein kinase activator activity 7/357 139/18639 0.0503597122302158 2.62928480744816 0.0177237158939335 0.187579819949026 GO:0032050 clathrin heavy chain binding 2/357 11/18639 0.181818181818182 9.49274255156608 0.0179483052665963 0.187579819949026 GO:0034056 estrogen response element binding 2/357 11/18639 0.181818181818182 9.49274255156608 0.0179483052665963 0.187579819949026 GO:0097493 structural molecule activity conferring elasticity 2/357 11/18639 0.181818181818182 9.49274255156608 0.0179483052665963 0.187579819949026 GO:0005003 ephrin receptor activity 4/357 53/18639 0.0754716981132075 3.94038370065007 0.0185532592918037 0.187579819949026 GO:0005005 transmembrane-ephrin receptor activity 4/357 53/18639 0.0754716981132075 3.94038370065007 0.0185532592918037 0.187579819949026 GO:0005516 calmodulin binding 9/357 207/18639 0.0434782608695652 2.27000365363537 0.0186048069773788 0.187579819949026 GO:0032452 histone demethylase activity 3/357 30/18639 0.1 5.22100840336134 0.0192977484878933 0.187579819949026 GO:0051721 protein phosphatase 2A binding 3/357 30/18639 0.1 5.22100840336134 0.0192977484878933 0.187579819949026 GO:0140457 protein demethylase activity 3/357 31/18639 0.0967741935483871 5.05258877744646 0.0210688980767674 0.187579819949026 GO:0000340 RNA 7-methylguanosine cap binding 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0005025 transforming growth factor beta receptor activity, type I 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0005026 transforming growth factor beta receptor activity, type II 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0016361 activin receptor activity, type I 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0016362 activin receptor activity, type II 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0017002 activin receptor activity 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/357 12/18639 0.166666666666667 8.70168067226891 0.0212683627889572 0.187579819949026 GO:0035091 phosphatidylinositol binding 11/357 284/18639 0.0387323943661972 2.02222156468221 0.0214746552493368 0.187579819949026 GO:0004535 poly(A)-specific ribonuclease activity 2/357 13/18639 0.153846153846154 8.03232062055592 0.0248212166256798 0.21297557183708 GO:0061980 regulatory RNA binding 4/357 58/18639 0.0689655172413793 3.60069545059403 0.0249695498015886 0.21297557183708 GO:0031593 polyubiquitin modification-dependent protein binding 4/357 59/18639 0.0677966101694915 3.53966671414328 0.0263940292487213 0.21464625553692 GO:0045309 protein phosphorylated amino acid binding 4/357 59/18639 0.0677966101694915 3.53966671414328 0.0263940292487213 0.21464625553692 GO:0051427 hormone receptor binding 3/357 34/18639 0.0882352941176471 4.60677212061295 0.0268990130784682 0.21464625553692 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/357 60/18639 0.0666666666666667 3.48067226890756 0.0278663066842227 0.21464625553692 GO:0003727 single-stranded RNA binding 5/357 89/18639 0.0561797752808989 2.93315078840525 0.0281563233001937 0.21464625553692 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/357 89/18639 0.0561797752808989 2.93315078840525 0.0281563233001937 0.21464625553692 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/357 89/18639 0.0561797752808989 2.93315078840525 0.0281563233001937 0.21464625553692 GO:0005545 1-phosphatidylinositol binding 2/357 14/18639 0.142857142857143 7.45858343337335 0.0285967834939457 0.21464625553692 GO:0008494 translation activator activity 2/357 14/18639 0.142857142857143 7.45858343337335 0.0285967834939457 0.21464625553692 GO:0032454 histone H3K9 demethylase activity 2/357 14/18639 0.142857142857143 7.45858343337335 0.0285967834939457 0.21464625553692 GO:0098821 BMP receptor activity 2/357 14/18639 0.142857142857143 7.45858343337335 0.0285967834939457 0.21464625553692 GO:0061631 ubiquitin conjugating enzyme activity 3/357 35/18639 0.0857142857142857 4.47515006002401 0.0290142524725768 0.21464625553692 GO:0140566 histone reader activity 3/357 35/18639 0.0857142857142857 4.47515006002401 0.0290142524725768 0.21464625553692 GO:0140793 histone H2AXY142 phosphatase activity 5/357 90/18639 0.0555555555555556 2.90056022408964 0.0293622304830701 0.215026435355816 GO:0031625 ubiquitin protein ligase binding 11/357 302/18639 0.0364238410596026 1.90169180254883 0.031716196192856 0.229942422398206 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/357 15/18639 0.133333333333333 6.96134453781513 0.0325852790791395 0.233904231013625 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/357 38/18639 0.0789473684210526 4.1218487394958 0.0358713564056905 0.25253781856996 GO:0008276 protein methyltransferase activity 5/357 95/18639 0.0526315789473684 2.74789915966387 0.0358777866382151 0.25253781856996 GO:0035591 signaling adaptor activity 6/357 129/18639 0.0465116279069767 2.42837600156342 0.0379591432911146 0.264619027750558 GO:0004725 protein tyrosine phosphatase activity 5/357 98/18639 0.0510204081632653 2.66377979763334 0.0401821469810796 0.274318080132191 GO:0004674 protein serine/threonine kinase activity 14/357 433/18639 0.0323325635103926 1.68808585789974 0.040193636382433 0.274318080132191 GO:0004532 RNA exonuclease activity 3/357 40/18639 0.075 3.91575630252101 0.040863934695554 0.274318080132191 GO:0032451 demethylase activity 3/357 40/18639 0.075 3.91575630252101 0.040863934695554 0.274318080132191 GO:0032934 sterol binding 4/357 68/18639 0.0588235294117647 3.07118141374197 0.0413879900625984 0.275287089865907 GO:0043130 ubiquitin binding 5/357 100/18639 0.05 2.61050420168067 0.0432185773988299 0.28148560824754 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/357 41/18639 0.0731707317073171 3.82025005124001 0.0434846732741028 0.28148560824754 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/357 41/18639 0.0731707317073171 3.82025005124001 0.0434846732741028 0.28148560824754 GO:0050811 GABA receptor binding 2/357 18/18639 0.111111111111111 5.80112044817927 0.0457348190808937 0.293431361359716 GO:0044389 ubiquitin-like protein ligase binding 11/357 322/18639 0.0341614906832298 1.78357429928493 0.0467211623994935 0.296612646025543 GO:0140789 histone phosphatase activity 6/357 136/18639 0.0441176470588235 2.30338606030648 0.0470489024730172 0.296612646025543 GO:0048156 tau protein binding 3/357 43/18639 0.0697674418604651 3.64256400234512 0.0489711756360591 0.306069847725369 GO:0140297 DNA-binding transcription factor binding 15/357 488/18639 0.0307377049180328 1.60481815677091 0.0497192059448365 0.307563886918034 GO:0030506 ankyrin binding 2/357 19/18639 0.105263157894737 5.49579831932773 0.0504829000596498 0.307563886918034 GO:1990380 K48-linked deubiquitinase activity 2/357 19/18639 0.105263157894737 5.49579831932773 0.0504829000596498 0.307563886918034 GO:0001046 core promoter sequence-specific DNA binding 3/357 44/18639 0.0681818181818182 3.55977845683728 0.0518352015984293 0.313171009657177 GO:0019888 protein phosphatase regulator activity 5/357 107/18639 0.0467289719626168 2.43972355297259 0.0549072928245875 0.328989977667983 GO:0019003 GDP binding 4/357 75/18639 0.0533333333333333 2.78453781512605 0.0557789775759817 0.331473432316284 GO:0005543 phospholipid binding 15/357 497/18639 0.0301810865191147 1.57575706338874 0.0564614760248613 0.332801383073369 GO:0098631 cell adhesion mediator activity 4/357 76/18639 0.0526315789473684 2.74789915966387 0.0580285541396854 0.339279852832838 GO:0010314 phosphatidylinositol-5-phosphate binding 2/357 21/18639 0.0952380952380952 4.97238895558223 0.0604756015691024 0.343728696065688 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/357 48/18639 0.0625 3.26313025210084 0.064073617798534 0.343728696065688 GO:0140693 molecular condensate scaffold activity 3/357 48/18639 0.0625 3.26313025210084 0.064073617798534 0.343728696065688 GO:0050321 tau-protein kinase activity 2/357 22/18639 0.0909090909090909 4.74637127578304 0.065704179030639 0.343728696065688 GO:0070034 telomerase RNA binding 2/357 22/18639 0.0909090909090909 4.74637127578304 0.065704179030639 0.343728696065688 GO:0140517 protein-RNA adaptor activity 2/357 22/18639 0.0909090909090909 4.74637127578304 0.065704179030639 0.343728696065688 GO:1901981 phosphatidylinositol phosphate binding 7/357 185/18639 0.0378378378378378 1.97551669316375 0.0658285265704057 0.343728696065688 GO:0003730 mRNA 3'-UTR binding 9/357 262/18639 0.0343511450381679 1.79347616909359 0.0660054559384718 0.343728696065688 GO:0005004 GPI-linked ephrin receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0005008 hepatocyte growth factor receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0005009 insulin receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0005011 macrophage colony-stimulating factor receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0005020 stem cell factor receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0008288 boss receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0036332 placental growth factor receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0038062 protein tyrosine kinase collagen receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0060175 brain-derived neurotrophic factor receptor activity 3/357 49/18639 0.0612244897959184 3.19653575716001 0.0673234135742451 0.343728696065688 GO:0005006 epidermal growth factor receptor activity 3/357 50/18639 0.06 3.13260504201681 0.0706469809377641 0.348182656198837 GO:0005007 fibroblast growth factor receptor activity 3/357 50/18639 0.06 3.13260504201681 0.0706469809377641 0.348182656198837 GO:0005017 platelet-derived growth factor receptor activity 3/357 50/18639 0.06 3.13260504201681 0.0706469809377641 0.348182656198837 GO:0005019 platelet-derived growth factor beta-receptor activity 3/357 50/18639 0.06 3.13260504201681 0.0706469809377641 0.348182656198837 GO:0070577 lysine-acetylated histone binding 2/357 23/18639 0.0869565217391304 4.54000730727073 0.0710772870585213 0.348182656198837 GO:0140103 catalytic activity, acting on a glycoprotein 2/357 23/18639 0.0869565217391304 4.54000730727073 0.0710772870585213 0.348182656198837 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 11/357 349/18639 0.0315186246418338 1.64559004117406 0.0737705304761157 0.35316610515854 GO:0005010 insulin-like growth factor receptor activity 3/357 51/18639 0.0588235294117647 3.07118141374197 0.0740431006677214 0.35316610515854 GO:0005021 vascular endothelial growth factor receptor activity 3/357 51/18639 0.0588235294117647 3.07118141374197 0.0740431006677214 0.35316610515854 GO:0005030 neurotrophin receptor activity 3/357 51/18639 0.0588235294117647 3.07118141374197 0.0740431006677214 0.35316610515854 GO:0030215 semaphorin receptor binding 2/357 24/18639 0.0833333333333333 4.35084033613445 0.0765875067401115 0.357930745568131 GO:0048027 mRNA 5'-UTR binding 2/357 24/18639 0.0833333333333333 4.35084033613445 0.0765875067401115 0.357930745568131 GO:0050431 transforming growth factor beta binding 2/357 24/18639 0.0833333333333333 4.35084033613445 0.0765875067401115 0.357930745568131 GO:0005080 protein kinase C binding 3/357 52/18639 0.0576923076923077 3.01212023270847 0.077510520074754 0.357930745568131 GO:0030159 signaling receptor complex adaptor activity 3/357 52/18639 0.0576923076923077 3.01212023270847 0.077510520074754 0.357930745568131 GO:0032182 ubiquitin-like protein binding 5/357 120/18639 0.0416666666666667 2.17542016806723 0.0809942300215433 0.365736475254051 GO:0038064 collagen receptor activity 3/357 53/18639 0.0566037735849057 2.95528777548755 0.081047955721731 0.365736475254051 GO:0051018 protein kinase A binding 3/357 53/18639 0.0566037735849057 2.95528777548755 0.081047955721731 0.365736475254051 GO:0003707 nuclear steroid receptor activity 2/357 25/18639 0.08 4.17680672268908 0.0822276489191866 0.365736475254051 GO:0008139 nuclear localization sequence binding 2/357 25/18639 0.08 4.17680672268908 0.0822276489191866 0.365736475254051 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/357 25/18639 0.08 4.17680672268908 0.0822276489191866 0.365736475254051 GO:0015485 cholesterol binding 3/357 54/18639 0.0555555555555556 2.90056022408964 0.0846540960338902 0.374233046491283 GO:0050681 nuclear androgen receptor binding 2/357 26/18639 0.0769230769230769 4.01616031027796 0.0879907481572003 0.385768149137121 GO:0140313 molecular sequestering activity 3/357 55/18639 0.0545454545454545 2.84782276546982 0.0883276038024304 0.385768149137121 GO:0008266 poly(U) RNA binding 2/357 27/18639 0.0740740740740741 3.86741363211951 0.0938700568405486 0.407519707840705 GO:0004601 peroxidase activity 3/357 57/18639 0.0526315789473684 2.74789915966387 0.0958712590064651 0.413730135593376 GO:0045499 chemorepellent activity 2/357 28/18639 0.0714285714285714 3.72929171668667 0.0998590394304843 0.425869432865301 GO:0051019 mitogen-activated protein kinase binding 2/357 28/18639 0.0714285714285714 3.72929171668667 0.0998590394304843 0.425869432865301 GO:0019207 kinase regulator activity 9/357 287/18639 0.0313588850174216 1.63725002196 0.101684767721714 0.429480884610246 GO:0051213 dioxygenase activity 4/357 93/18639 0.043010752688172 2.24559501219843 0.103346302793051 0.429480884610246 GO:0051219 phosphoprotein binding 4/357 93/18639 0.043010752688172 2.24559501219843 0.103346302793051 0.429480884610246 GO:0015459 potassium channel regulator activity 3/357 59/18639 0.0508474576271186 2.65475003560746 0.103667799733508 0.429480884610246 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/357 59/18639 0.0508474576271186 2.65475003560746 0.103667799733508 0.429480884610246 GO:0005201 extracellular matrix structural constituent 6/357 168/18639 0.0357142857142857 1.86464585834334 0.104517165149165 0.43053945871105 GO:0003785 actin monomer binding 2/357 29/18639 0.0689655172413793 3.60069545059403 0.105951366852404 0.433394113701621 GO:0042562 hormone binding 4/357 94/18639 0.0425531914893617 2.22170570355802 0.106405727226053 0.433394113701621 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/357 60/18639 0.05 2.61050420168067 0.107657351999259 0.433619889997017 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/357 60/18639 0.05 2.61050420168067 0.107657351999259 0.433619889997017 GO:0008187 poly-pyrimidine tract binding 2/357 30/18639 0.0666666666666667 3.48067226890756 0.112140911021298 0.44427410104066 GO:0031624 ubiquitin conjugating enzyme binding 2/357 30/18639 0.0666666666666667 3.48067226890756 0.112140911021298 0.44427410104066 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/357 30/18639 0.0666666666666667 3.48067226890756 0.112140911021298 0.44427410104066 GO:0004721 phosphoprotein phosphatase activity 6/357 175/18639 0.0342857142857143 1.7900600240096 0.120495217818405 0.47265173579203 GO:0016779 nucleotidyltransferase activity 5/357 136/18639 0.0367647058823529 1.91948838358873 0.120607684305553 0.47265173579203 GO:0051059 NF-kappaB binding 2/357 32/18639 0.0625 3.26313025210084 0.124788110288789 0.483804170905734 GO:0140142 nucleocytoplasmic carrier activity 2/357 32/18639 0.0625 3.26313025210084 0.124788110288789 0.483804170905734 GO:0140767 enzyme-substrate adaptor activity 5/357 139/18639 0.0359712230215827 1.87806057674868 0.128893224821632 0.497061638274909 GO:0071889 14-3-3 protein binding 2/357 33/18639 0.0606060606060606 3.16424751718869 0.131234466738493 0.499952086739798 GO:0140311 protein sequestering activity 2/357 33/18639 0.0606060606060606 3.16424751718869 0.131234466738493 0.499952086739798 GO:0004713 protein tyrosine kinase activity 5/357 140/18639 0.0357142857142857 1.86464585834334 0.131711515265243 0.499952086739798 GO:0016500 protein-hormone receptor activity 3/357 67/18639 0.0447761194029851 2.33776495672896 0.137152346703264 0.517475070618535 GO:0090482 vitamin transmembrane transporter activity 2/357 34/18639 0.0588235294117647 3.07118141374197 0.137755432592244 0.517475070618535 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/357 484/18639 0.0268595041322314 1.40233696784499 0.13979790275013 0.522440615947651 GO:0019955 cytokine binding 5/357 144/18639 0.0347222222222222 1.81285014005602 0.143258213781998 0.528538940303484 GO:0000175 3'-5'-RNA exonuclease activity 2/357 35/18639 0.0571428571428571 2.98343337334934 0.144345807144951 0.528538940303484 GO:0005154 epidermal growth factor receptor binding 2/357 35/18639 0.0571428571428571 2.98343337334934 0.144345807144951 0.528538940303484 GO:0005343 organic acid:sodium symporter activity 2/357 35/18639 0.0571428571428571 2.98343337334934 0.144345807144951 0.528538940303484 GO:0001216 DNA-binding transcription activator activity 13/357 491/18639 0.0264765784114053 1.38234438378203 0.150636128026716 0.53928771615185 GO:0000993 RNA polymerase II complex binding 2/357 36/18639 0.0555555555555556 2.90056022408964 0.151000560522518 0.53928771615185 GO:0004190 aspartic-type endopeptidase activity 2/357 36/18639 0.0555555555555556 2.90056022408964 0.151000560522518 0.53928771615185 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/357 36/18639 0.0555555555555556 2.90056022408964 0.151000560522518 0.53928771615185 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/357 36/18639 0.0555555555555556 2.90056022408964 0.151000560522518 0.53928771615185 GO:0023023 MHC protein complex binding 2/357 37/18639 0.0540540540540541 2.82216670451965 0.157714829076465 0.542217433353822 GO:0042805 actinin binding 2/357 37/18639 0.0540540540540541 2.82216670451965 0.157714829076465 0.542217433353822 GO:0043394 proteoglycan binding 2/357 37/18639 0.0540540540540541 2.82216670451965 0.157714829076465 0.542217433353822 GO:0070001 aspartic-type peptidase activity 2/357 37/18639 0.0540540540540541 2.82216670451965 0.157714829076465 0.542217433353822 GO:0043539 protein serine/threonine kinase activator activity 3/357 73/18639 0.0410958904109589 2.14561989179233 0.164349038333983 0.542217433353822 GO:0043531 ADP binding 2/357 38/18639 0.0526315789473684 2.74789915966387 0.164483910891508 0.542217433353822 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0008140 cAMP response element binding protein binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0008190 eukaryotic initiation factor 4E binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0015187 glycine transmembrane transporter activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0030957 Tat protein binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0031720 haptoglobin binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0042975 peroxisome proliferator activated receptor binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0045322 unmethylated CpG binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0051864 histone H3K36 demethylase activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0051880 G-quadruplex DNA binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0099122 RNA polymerase II C-terminal domain binding 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0140999 histone H3K4 trimethyltransferase activity 1/357 10/18639 0.1 5.22100840336134 0.175879948592793 0.542217433353822 GO:0015144 carbohydrate transmembrane transporter activity 2/357 40/18639 0.05 2.61050420168067 0.178168489124932 0.542217433353822 GO:0071949 FAD binding 2/357 40/18639 0.05 2.61050420168067 0.178168489124932 0.542217433353822 GO:0017124 SH3 domain binding 4/357 115/18639 0.0347826086956522 1.81600292290829 0.179134437194337 0.542217433353822 GO:0035401 histone H3Y41 kinase activity 4/357 115/18639 0.0347826086956522 1.81600292290829 0.179134437194337 0.542217433353822 GO:0140801 histone H2AXY142 kinase activity 4/357 115/18639 0.0347826086956522 1.81600292290829 0.179134437194337 0.542217433353822 GO:0001727 lipid kinase activity 2/357 41/18639 0.0487804878048781 2.54683336749334 0.185075351476257 0.542217433353822 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/357 41/18639 0.0487804878048781 2.54683336749334 0.185075351476257 0.542217433353822 GO:0042287 MHC protein binding 2/357 41/18639 0.0487804878048781 2.54683336749334 0.185075351476257 0.542217433353822 GO:0003924 GTPase activity 9/357 331/18639 0.027190332326284 1.41960953565716 0.186176342592287 0.542217433353822 GO:1990782 protein tyrosine kinase binding 4/357 117/18639 0.0341880341880342 1.78496013790131 0.186787358689969 0.542217433353822 GO:0002162 dystroglycan binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0004016 adenylate cyclase activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0005114 type II transforming growth factor beta receptor binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0005225 volume-sensitive anion channel activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0008172 S-methyltransferase activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0008432 JUN kinase binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0008503 benzodiazepine receptor activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0019107 myristoyltransferase activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0019206 nucleoside kinase activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0043522 leucine zipper domain binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0047676 arachidonate-CoA ligase activity 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0048407 platelet-derived growth factor binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0050998 nitric-oxide synthase binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0070697 activin receptor binding 1/357 11/18639 0.0909090909090909 4.74637127578304 0.191673112925413 0.542217433353822 GO:0043175 RNA polymerase core enzyme binding 2/357 42/18639 0.0476190476190476 2.48619447779112 0.192019750719299 0.542217433353822 GO:0048487 beta-tubulin binding 2/357 42/18639 0.0476190476190476 2.48619447779112 0.192019750719299 0.542217433353822 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/357 43/18639 0.0465116279069767 2.42837600156342 0.198997729991652 0.542217433353822 GO:0008375 acetylglucosaminyltransferase activity 2/357 43/18639 0.0465116279069767 2.42837600156342 0.198997729991652 0.542217433353822 GO:0004540 RNA nuclease activity 4/357 121/18639 0.0330578512396694 1.72595319119383 0.202398912433151 0.542217433353822 GO:0015101 organic cation transmembrane transporter activity 3/357 81/18639 0.037037037037037 1.93370681605976 0.202784211120569 0.542217433353822 GO:0030971 receptor tyrosine kinase binding 3/357 81/18639 0.037037037037037 1.93370681605976 0.202784211120569 0.542217433353822 GO:0019205 nucleobase-containing compound kinase activity 2/357 44/18639 0.0454545454545455 2.37318563789152 0.206005469438949 0.542217433353822 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/357 44/18639 0.0454545454545455 2.37318563789152 0.206005469438949 0.542217433353822 GO:0005049 nuclear export signal receptor activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0005078 MAP-kinase scaffold activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0008179 adenylate cyclase binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0008603 cAMP-dependent protein kinase regulator activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0016208 AMP binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0016273 arginine N-methyltransferase activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0016274 protein-arginine N-methyltransferase activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0017166 vinculin binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0035197 siRNA binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0042301 phosphate ion binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0045295 gamma-catenin binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0070410 co-SMAD binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0097677 STAT family protein binding 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:1990817 poly(A) RNA polymerase activity 1/357 12/18639 0.0833333333333333 4.35084033613445 0.207164453846909 0.542217433353822 GO:0030165 PDZ domain binding 3/357 83/18639 0.036144578313253 1.88711147109446 0.212704396189366 0.55398900213445 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/357 167/18639 0.029940119760479 1.56317616867106 0.217085038836307 0.55398900213445 GO:0004527 exonuclease activity 3/357 84/18639 0.0357142857142857 1.86464585834334 0.217703538844555 0.55398900213445 GO:0051117 ATPase binding 3/357 84/18639 0.0357142857142857 1.86464585834334 0.217703538844555 0.55398900213445 GO:0019887 protein kinase regulator activity 7/357 255/18639 0.0274509803921569 1.43321799307958 0.218398169645018 0.55398900213445 GO:0030276 clathrin binding 2/357 46/18639 0.0434782608695652 2.27000365363537 0.220095611943345 0.55398900213445 GO:0030291 protein serine/threonine kinase inhibitor activity 2/357 46/18639 0.0434782608695652 2.27000365363537 0.220095611943345 0.55398900213445 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0031994 insulin-like growth factor I binding 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0046974 histone H3K9 methyltransferase activity 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0046975 histone H3K36 methyltransferase activity 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0061459 L-arginine transmembrane transporter activity 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0097157 pre-mRNA intronic binding 1/357 13/18639 0.0769230769230769 4.01616031027796 0.222359723615345 0.55398900213445 GO:0001784 phosphotyrosine residue binding 2/357 47/18639 0.0425531914893617 2.22170570355802 0.227171026850603 0.556011955130928 GO:0043495 protein-membrane adaptor activity 2/357 47/18639 0.0425531914893617 2.22170570355802 0.227171026850603 0.556011955130928 GO:0140938 histone H3 methyltransferase activity 2/357 47/18639 0.0425531914893617 2.22170570355802 0.227171026850603 0.556011955130928 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/357 86/18639 0.0348837209302326 1.82128200117256 0.22777317334329 0.556011955130928 GO:0016209 antioxidant activity 3/357 86/18639 0.0348837209302326 1.82128200117256 0.22777317334329 0.556011955130928 GO:0050660 flavin adenine dinucleotide binding 3/357 86/18639 0.0348837209302326 1.82128200117256 0.22777317334329 0.556011955130928 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/357 128/18639 0.03125 1.63156512605042 0.230583545933219 0.556447110569612 GO:0032266 phosphatidylinositol-3-phosphate binding 2/357 48/18639 0.0416666666666667 2.17542016806723 0.234262218548519 0.556447110569612 GO:0008201 heparin binding 5/357 172/18639 0.0290697674418605 1.51773500097714 0.234513907782543 0.556447110569612 GO:0004705 JUN kinase activity 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0005344 oxygen carrier activity 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0008191 metalloendopeptidase inhibitor activity 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0043176 amine binding 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0044548 S100 protein binding 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0070742 C2H2 zinc finger domain binding 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:1901474 azole transmembrane transporter activity 1/357 14/18639 0.0714285714285714 3.72929171668667 0.237264565163145 0.556447110569612 GO:0004197 cysteine-type endopeptidase activity 3/357 88/18639 0.0340909090909091 1.77988922841864 0.237929109347007 0.556447110569612 GO:0141003 histone H2AX kinase activity 9/357 354/18639 0.0254237288135593 1.32737501780373 0.239738340041658 0.558875551544059 GO:0140996 histone H3 kinase activity 9/357 357/18639 0.0252100840336134 1.31622060588941 0.247104034012645 0.57067585241447 GO:0005179 hormone activity 4/357 132/18639 0.0303030303030303 1.58212375859435 0.247106493965449 0.57067585241447 GO:0004089 carbonate dehydratase activity 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0004467 long-chain fatty acid-CoA ligase activity 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0017081 chloride channel regulator activity 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0051371 muscle alpha-actinin binding 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0061578 K63-linked deubiquitinase activity 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0140776 protein-containing complex destabilizing activity 1/357 15/18639 0.0666666666666667 3.48067226890756 0.251884514169145 0.57067585241447 GO:0035173 histone kinase activity 9/357 360/18639 0.025 1.30525210084034 0.254546254651473 0.573713227134241 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/357 268/18639 0.0261194029850746 1.36369622475856 0.255286366834533 0.573713227134241 GO:0005048 signal sequence binding 2/357 51/18639 0.0392156862745098 2.04745427582798 0.255599134295669 0.573713227134241 GO:0043178 alcohol binding 3/357 92/18639 0.0326086956521739 1.70250274022653 0.258458619727034 0.577317615571121 GO:0042578 phosphoric ester hydrolase activity 9/357 363/18639 0.0247933884297521 1.29446489339537 0.262061417797187 0.577317615571121 GO:0002020 protease binding 4/357 136/18639 0.0294117647058824 1.53559070687098 0.263878077584198 0.577317615571121 GO:0044325 transmembrane transporter binding 4/357 136/18639 0.0294117647058824 1.53559070687098 0.263878077584198 0.577317615571121 GO:0004707 MAP kinase activity 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0008142 oxysterol binding 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0022858 alanine transmembrane transporter activity 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0030275 LRR domain binding 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0034450 ubiquitin-ubiquitin ligase activity 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0070411 I-SMAD binding 1/357 16/18639 0.0625 3.26313025210084 0.266225001091483 0.577317615571121 GO:0016922 nuclear receptor binding 4/357 137/18639 0.0291970802919708 1.52438201557995 0.268104756757959 0.577317615571121 GO:0004864 protein phosphatase inhibitor activity 2/357 53/18639 0.0377358490566038 1.97019185032504 0.269847177811281 0.577317615571121 GO:0017046 peptide hormone binding 2/357 53/18639 0.0377358490566038 1.97019185032504 0.269847177811281 0.577317615571121 GO:0140296 general transcription initiation factor binding 2/357 53/18639 0.0377358490566038 1.97019185032504 0.269847177811281 0.577317615571121 GO:0016791 phosphatase activity 7/357 273/18639 0.0256410256410256 1.33872010342599 0.269945754039462 0.577317615571121 GO:0050661 NADP binding 2/357 54/18639 0.037037037037037 1.93370681605976 0.276969988648873 0.583940319087623 GO:0004896 cytokine receptor activity 3/357 96/18639 0.03125 1.63156512605042 0.279212177400252 0.583940319087623 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:0008429 phosphatidylethanolamine binding 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:0031489 myosin V binding 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:0032183 SUMO binding 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:0038191 neuropilin binding 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:1990226 histone methyltransferase binding 1/357 17/18639 0.0588235294117647 3.07118141374197 0.280291353162059 0.583940319087623 GO:0098632 cell-cell adhesion mediator activity 2/357 55/18639 0.0363636363636364 1.89854851031322 0.284088569209116 0.588989992676506 GO:0001217 DNA-binding transcription repressor activity 7/357 278/18639 0.0251798561151079 1.31464240372408 0.284825423300197 0.588989992676506 GO:0008170 N-methyltransferase activity 3/357 98/18639 0.0306122448979592 1.59826787858 0.289649210442837 0.588989992676506 GO:0019212 phosphatase inhibitor activity 2/357 56/18639 0.0357142857142857 1.86464585834334 0.291200474787787 0.588989992676506 GO:0046943 carboxylic acid transmembrane transporter activity 5/357 188/18639 0.0265957446808511 1.38856606472376 0.292561688850423 0.588989992676506 GO:0008409 5'-3' exonuclease activity 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0017128 phospholipid scramblase activity 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0022851 GABA-gated chloride ion channel activity 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0031690 adrenergic receptor binding 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0070064 proline-rich region binding 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0098641 cadherin binding involved in cell-cell adhesion 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:1990381 ubiquitin-specific protease binding 1/357 18/18639 0.0555555555555556 2.90056022408964 0.294088796343304 0.588989992676506 GO:0005342 organic acid transmembrane transporter activity 5/357 189/18639 0.0264550264550265 1.3812191543284 0.296278348523417 0.591740503249249 GO:0008408 3'-5' exonuclease activity 2/357 58/18639 0.0344827586206897 1.80034772529702 0.305394952875887 0.597925687680335 GO:0015293 symporter activity 4/357 146/18639 0.0273972602739726 1.43041326119489 0.306614928895714 0.597925687680335 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0004890 GABA-A receptor activity 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0005520 insulin-like growth factor binding 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0015245 fatty acid transmembrane transporter activity 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0042800 histone H3K4 methyltransferase activity 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0043395 heparan sulfate proteoglycan binding 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0050145 nucleoside monophosphate kinase activity 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0140036 ubiquitin-modified protein reader activity 1/357 19/18639 0.0526315789473684 2.74789915966387 0.307622457247951 0.597925687680335 GO:0015631 tubulin binding 9/357 385/18639 0.0233766233766234 1.22049547091564 0.31905079702156 0.612238393792967 GO:0001098 basal transcription machinery binding 2/357 60/18639 0.0333333333333333 1.74033613445378 0.319535710551937 0.612238393792967 GO:0001099 basal RNA polymerase II transcription machinery binding 2/357 60/18639 0.0333333333333333 1.74033613445378 0.319535710551937 0.612238393792967 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/357 60/18639 0.0333333333333333 1.74033613445378 0.319535710551937 0.612238393792967 GO:0016408 C-acyltransferase activity 1/357 20/18639 0.05 2.61050420168067 0.320897365022521 0.612238393792967 GO:0043024 ribosomal small subunit binding 1/357 20/18639 0.05 2.61050420168067 0.320897365022521 0.612238393792967 GO:0061608 nuclear import signal receptor activity 1/357 20/18639 0.05 2.61050420168067 0.320897365022521 0.612238393792967 GO:0015026 coreceptor activity 2/357 61/18639 0.0327868852459016 1.71180603388897 0.326580790984946 0.619090288372753 GO:0016836 hydro-lyase activity 2/357 61/18639 0.0327868852459016 1.71180603388897 0.326580790984946 0.619090288372753 GO:0140857 histone H3T45 kinase activity 6/357 246/18639 0.024390243902439 1.27341668374667 0.332746636793233 0.619090288372753 GO:0015179 L-amino acid transmembrane transporter activity 2/357 62/18639 0.032258064516129 1.68419625914882 0.333606423942005 0.619090288372753 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/357 21/18639 0.0476190476190476 2.48619447779112 0.333918453195192 0.619090288372753 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/357 21/18639 0.0476190476190476 2.48619447779112 0.333918453195192 0.619090288372753 GO:0009975 cyclase activity 1/357 21/18639 0.0476190476190476 2.48619447779112 0.333918453195192 0.619090288372753 GO:0015174 basic amino acid transmembrane transporter activity 1/357 21/18639 0.0476190476190476 2.48619447779112 0.333918453195192 0.619090288372753 GO:0036122 BMP binding 1/357 21/18639 0.0476190476190476 2.48619447779112 0.333918453195192 0.619090288372753 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/357 21/18639 0.0476190476190476 2.48619447779112 0.333918453195192 0.619090288372753 GO:0004679 AMP-activated protein kinase activity 6/357 248/18639 0.0241935483870968 1.26314719436162 0.339523146510289 0.619090288372753 GO:0004843 cysteine-type deubiquitinase activity 3/357 108/18639 0.0277777777777778 1.45028011204482 0.342085720199493 0.619090288372753 GO:0032931 histone H3K56 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0043992 histone H3K9 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0043993 histone H3K18 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0043994 histone H3K23 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0043999 histone H2AK5 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0044012 histone H2AK9 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0044014 histone H2BK5 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0044015 histone H2BK12 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0044016 histone H3K4 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0044017 histone H3K27 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0044018 histone H3K36 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0046972 histone H4K16 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0140035 ubiquitin-like protein reader activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0140908 histone H3K122 acetyltransferase activity 1/357 22/18639 0.0454545454545455 2.37318563789152 0.346690561488742 0.619090288372753 GO:0140375 immune receptor activity 4/357 156/18639 0.0256410256410256 1.33872010342599 0.349999302125264 0.621559349067839 GO:0008168 methyltransferase activity 5/357 204/18639 0.0245098039215686 1.27965892239249 0.352751817324232 0.621559349067839 GO:1902936 phosphatidylinositol bisphosphate binding 3/357 111/18639 0.027027027027027 1.41108335225982 0.357799980004577 0.621559349067839 GO:0005158 insulin receptor binding 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0005283 amino acid:sodium symporter activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0008171 O-methyltransferase activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0016849 phosphorus-oxygen lyase activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0016917 GABA receptor activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0017134 fibroblast growth factor binding 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0031681 G-protein beta-subunit binding 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0042171 lysophosphatidic acid acyltransferase activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0044013 histone H2B acetyltransferase activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0071617 lysophospholipid acyltransferase activity 1/357 23/18639 0.0434782608695652 2.27000365363537 0.359218437599206 0.621559349067839 GO:0005200 structural constituent of cytoskeleton 3/357 112/18639 0.0267857142857143 1.3984843937575 0.363027637761136 0.626654850897199 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/357 67/18639 0.0298507462686567 1.55850997115264 0.36838124787732 0.627248433719329 GO:0042054 histone methyltransferase activity 2/357 67/18639 0.0298507462686567 1.55850997115264 0.36838124787732 0.627248433719329 GO:0015295 solute:proton symporter activity 1/357 24/18639 0.0416666666666667 2.17542016806723 0.371506738940906 0.627248433719329 GO:0035035 histone acetyltransferase binding 1/357 24/18639 0.0416666666666667 2.17542016806723 0.371506738940906 0.627248433719329 GO:0043998 histone H2A acetyltransferase activity 1/357 24/18639 0.0416666666666667 2.17542016806723 0.371506738940906 0.627248433719329 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/357 24/18639 0.0416666666666667 2.17542016806723 0.371506738940906 0.627248433719329 GO:0004518 nuclease activity 5/357 209/18639 0.0239234449760766 1.24904507257448 0.3717402771047 0.627248433719329 GO:0005178 integrin binding 4/357 161/18639 0.0248447204968944 1.2971449449345 0.371749480680298 0.627248433719329 GO:0008083 growth factor activity 4/357 162/18639 0.0246913580246914 1.28913787737317 0.376095366434522 0.627248433719329 GO:0101005 deubiquitinase activity 3/357 115/18639 0.0260869565217391 1.36200219218122 0.378667362302223 0.627248433719329 GO:0002039 p53 binding 2/357 69/18639 0.0289855072463768 1.51333576909024 0.382096486426248 0.627248433719329 GO:0016279 protein-lysine N-methyltransferase activity 2/357 69/18639 0.0289855072463768 1.51333576909024 0.382096486426248 0.627248433719329 GO:0004709 MAP kinase kinase kinase activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0005251 delayed rectifier potassium channel activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0008483 transaminase activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0015645 fatty acid ligase activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0017025 TBP-class protein binding 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0017056 structural constituent of nuclear pore 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0019707 protein-cysteine S-acyltransferase activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0120515 fatty acid-CoA ligase activity 1/357 25/18639 0.04 2.08840336134454 0.383560034358478 0.627248433719329 GO:0015294 solute:monoatomic cation symporter activity 3/357 116/18639 0.0258620689655172 1.35026079397276 0.383863462719968 0.627248433719329 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/357 70/18639 0.0285714285714286 1.49171668667467 0.388906620252096 0.627248433719329 GO:0016278 lysine N-methyltransferase activity 2/357 70/18639 0.0285714285714286 1.49171668667467 0.388906620252096 0.627248433719329 GO:0016741 transferase activity, transferring one-carbon groups 5/357 215/18639 0.0232558139534884 1.21418800078171 0.39452780776629 0.627248433719329 GO:0004435 phosphatidylinositol phospholipase C activity 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0008157 protein phosphatase 1 binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0008198 ferrous iron binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0015145 monosaccharide transmembrane transporter activity 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0030247 polysaccharide binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0034237 protein kinase A regulatory subunit binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0043548 phosphatidylinositol 3-kinase binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0050750 low-density lipoprotein particle receptor binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0052742 phosphatidylinositol kinase activity 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0070006 metalloaminopeptidase activity 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0070412 R-SMAD binding 1/357 26/18639 0.0384615384615385 2.00808015513898 0.395382805806529 0.627248433719329 GO:0005518 collagen binding 2/357 72/18639 0.0277777777777778 1.45028011204482 0.402425514303518 0.637027287925875 GO:0015252 proton channel activity 1/357 27/18639 0.037037037037037 1.93370681605976 0.406979449997528 0.638658227809974 GO:0016405 CoA-ligase activity 1/357 27/18639 0.037037037037037 1.93370681605976 0.406979449997528 0.638658227809974 GO:0023026 MHC class II protein complex binding 1/357 27/18639 0.037037037037037 1.93370681605976 0.406979449997528 0.638658227809974 GO:0035255 ionotropic glutamate receptor binding 1/357 27/18639 0.037037037037037 1.93370681605976 0.406979449997528 0.638658227809974 GO:0003697 single-stranded DNA binding 3/357 121/18639 0.0247933884297521 1.29446489339537 0.409680673058182 0.641508613320047 GO:0031491 nucleosome binding 2/357 74/18639 0.027027027027027 1.41108335225982 0.415801404158309 0.643963594508353 GO:0016866 intramolecular transferase activity 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0036408 histone H3K14 acetyltransferase activity 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0046966 nuclear thyroid hormone receptor binding 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0050698 proteoglycan sulfotransferase activity 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0051119 sugar transmembrane transporter activity 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0051393 alpha-actinin binding 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/357 28/18639 0.0357142857142857 1.86464585834334 0.41835428001853 0.643963594508353 GO:0017022 myosin binding 2/357 76/18639 0.0263157894736842 1.37394957983193 0.429025674291441 0.651455767813927 GO:0004629 phospholipase C activity 1/357 29/18639 0.0344827586206897 1.80034772529702 0.42951152691732 0.651455767813927 GO:0005416 amino acid:monoatomic cation symporter activity 1/357 29/18639 0.0344827586206897 1.80034772529702 0.42951152691732 0.651455767813927 GO:0010484 histone H3 acetyltransferase activity 1/357 29/18639 0.0344827586206897 1.80034772529702 0.42951152691732 0.651455767813927 GO:0016417 S-acyltransferase activity 1/357 29/18639 0.0344827586206897 1.80034772529702 0.42951152691732 0.651455767813927 GO:0043236 laminin binding 1/357 29/18639 0.0344827586206897 1.80034772529702 0.42951152691732 0.651455767813927 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/357 29/18639 0.0344827586206897 1.80034772529702 0.42951152691732 0.651455767813927 GO:0005126 cytokine receptor binding 6/357 275/18639 0.0218181818181818 1.13912910618793 0.431582422462662 0.651869283927979 GO:1901681 sulfur compound binding 6/357 275/18639 0.0218181818181818 1.13912910618793 0.431582422462662 0.651869283927979 GO:0019783 ubiquitin-like protein peptidase activity 3/357 127/18639 0.0236220472440945 1.23330907166016 0.440209032521594 0.654365004943561 GO:0042826 histone deacetylase binding 3/357 127/18639 0.0236220472440945 1.23330907166016 0.440209032521594 0.654365004943561 GO:0001968 fibronectin binding 1/357 30/18639 0.0333333333333333 1.74033613445378 0.440455341258562 0.654365004943561 GO:0016769 transferase activity, transferring nitrogenous groups 1/357 30/18639 0.0333333333333333 1.74033613445378 0.440455341258562 0.654365004943561 GO:0033612 receptor serine/threonine kinase binding 1/357 30/18639 0.0333333333333333 1.74033613445378 0.440455341258562 0.654365004943561 GO:0043995 histone H4K5 acetyltransferase activity 1/357 30/18639 0.0333333333333333 1.74033613445378 0.440455341258562 0.654365004943561 GO:0043996 histone H4K8 acetyltransferase activity 1/357 30/18639 0.0333333333333333 1.74033613445378 0.440455341258562 0.654365004943561 GO:0043997 histone H4K12 acetyltransferase activity 1/357 30/18639 0.0333333333333333 1.74033613445378 0.440455341258562 0.654365004943561 GO:0015370 solute:sodium symporter activity 2/357 79/18639 0.0253164556962025 1.32177427933199 0.448561038572013 0.658949190750088 GO:0016835 carbon-oxygen lyase activity 2/357 79/18639 0.0253164556962025 1.32177427933199 0.448561038572013 0.658949190750088 GO:0016411 acylglycerol O-acyltransferase activity 1/357 31/18639 0.032258064516129 1.68419625914882 0.451189794650507 0.658949190750088 GO:0016878 acid-thiol ligase activity 1/357 31/18639 0.032258064516129 1.68419625914882 0.451189794650507 0.658949190750088 GO:0070273 phosphatidylinositol-4-phosphate binding 1/357 31/18639 0.032258064516129 1.68419625914882 0.451189794650507 0.658949190750088 GO:0070325 lipoprotein particle receptor binding 1/357 31/18639 0.032258064516129 1.68419625914882 0.451189794650507 0.658949190750088 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/357 130/18639 0.0230769230769231 1.20484809308339 0.455247866094103 0.658949190750088 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/357 181/18639 0.0220994475138122 1.15381401179256 0.457633386959275 0.658949190750088 GO:0001618 virus receptor activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0033192 calmodulin-dependent protein phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0140791 histone H2AXS140 phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/357 81/18639 0.0246913580246914 1.28913787737317 0.461374053146796 0.658949190750088 GO:0031369 translation initiation factor binding 1/357 32/18639 0.03125 1.63156512605042 0.46171888124282 0.658949190750088 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/357 32/18639 0.03125 1.63156512605042 0.46171888124282 0.658949190750088 GO:0120015 sterol transfer activity 1/357 32/18639 0.03125 1.63156512605042 0.46171888124282 0.658949190750088 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/357 82/18639 0.024390243902439 1.27341668374667 0.467715133670564 0.663588007653931 GO:0033549 MAP kinase phosphatase activity 2/357 82/18639 0.024390243902439 1.27341668374667 0.467715133670564 0.663588007653931 GO:0140272 exogenous protein binding 2/357 82/18639 0.024390243902439 1.27341668374667 0.467715133670564 0.663588007653931 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/357 33/18639 0.0303030303030303 1.58212375859435 0.47204651919608 0.665311405335695 GO:0019239 deaminase activity 1/357 33/18639 0.0303030303030303 1.58212375859435 0.47204651919608 0.665311405335695 GO:0030296 protein tyrosine kinase activator activity 1/357 33/18639 0.0303030303030303 1.58212375859435 0.47204651919608 0.665311405335695 GO:0001540 amyloid-beta binding 2/357 83/18639 0.0240963855421687 1.25807431406297 0.474011695089853 0.665311405335695 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/357 83/18639 0.0240963855421687 1.25807431406297 0.474011695089853 0.665311405335695 GO:0004860 protein kinase inhibitor activity 2/357 84/18639 0.0238095238095238 1.24309723889556 0.48026311353486 0.665311405335695 GO:0017018 myosin phosphatase activity 2/357 84/18639 0.0238095238095238 1.24309723889556 0.48026311353486 0.665311405335695 GO:0015035 protein-disulfide reductase activity 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0016831 carboxy-lyase activity 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0019825 oxygen binding 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0030332 cyclin binding 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/357 34/18639 0.0294117647058824 1.53559070687098 0.482176552123469 0.665311405335695 GO:0008234 cysteine-type peptidase activity 4/357 187/18639 0.0213903743315508 1.11679324136072 0.482694895457346 0.665311405335695 GO:0010485 histone H4 acetyltransferase activity 1/357 35/18639 0.0285714285714286 1.49171668667467 0.492112750505191 0.667120741192009 GO:0016229 steroid dehydrogenase activity 1/357 35/18639 0.0285714285714286 1.49171668667467 0.492112750505191 0.667120741192009 GO:0005539 glycosaminoglycan binding 5/357 242/18639 0.0206611570247934 1.07872074449615 0.495241555916134 0.667120741192009 GO:0008081 phosphoric diester hydrolase activity 2/357 87/18639 0.0229885057471264 1.20023181686468 0.498740865386862 0.667120741192009 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/357 243/18639 0.0205761316872428 1.07428156447764 0.498868169725257 0.667120741192009 GO:0005484 SNAP receptor activity 1/357 36/18639 0.0277777777777778 1.45028011204482 0.501858813076124 0.667120741192009 GO:0016409 palmitoyltransferase activity 1/357 36/18639 0.0277777777777778 1.45028011204482 0.501858813076124 0.667120741192009 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0004711 ribosomal protein S6 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0035175 histone H3S10 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0035979 histone H2AXS139 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0044022 histone H3S28 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0044023 histone H4S1 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0044024 histone H2AS1 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0044025 histone H2BS14 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0072354 histone H3T3 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0072371 histone H2AS121 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0140823 histone H2BS36 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0140855 histone H3S57 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0140995 histone H2A kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0140997 histone H4 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0140998 histone H2B kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:1990244 histone H2AT120 kinase activity 5/357 245/18639 0.0204081632653061 1.06551191905334 0.506091596766352 0.667120741192009 GO:0004677 DNA-dependent protein kinase activity 5/357 246/18639 0.0203252032520325 1.06118056978889 0.509687965230525 0.670642059513848 GO:0035402 histone H3T11 kinase activity 5/357 247/18639 0.0202429149797571 1.05688429217841 0.513273813900874 0.672917748785052 GO:0035403 histone H3T6 kinase activity 5/357 247/18639 0.0202429149797571 1.05688429217841 0.513273813900874 0.672917748785052 GO:0019210 kinase inhibitor activity 2/357 90/18639 0.0222222222222222 1.16022408963585 0.516793571242415 0.676309276445398 GO:0042277 peptide binding 5/357 249/18639 0.0200803212851406 1.04839526171915 0.520413106836775 0.676660137952229 GO:0140104 molecular carrier activity 5/357 249/18639 0.0200803212851406 1.04839526171915 0.520413106836775 0.676660137952229 GO:0000146 microfilament motor activity 1/357 38/18639 0.0263157894736842 1.37394957983193 0.520794975141164 0.676660137952229 GO:0042162 telomeric DNA binding 1/357 38/18639 0.0263157894736842 1.37394957983193 0.520794975141164 0.676660137952229 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/357 39/18639 0.0256410256410256 1.33872010342599 0.529992125502682 0.687377980303121 GO:0016829 lyase activity 4/357 200/18639 0.02 1.04420168067227 0.535303537451408 0.689214465923313 GO:0004177 aminopeptidase activity 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:0015036 disulfide oxidoreductase activity 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:0030331 nuclear estrogen receptor binding 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:0050997 quaternary ammonium group binding 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:0061791 GTPase motor activity 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:1990606 membrane scission GTPase motor activity 1/357 40/18639 0.025 1.30525210084034 0.539013244384163 0.689214465923313 GO:0106310 protein serine kinase activity 7/357 361/18639 0.0193905817174515 1.01238390092879 0.54012249220811 0.689416913469859 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/357 41/18639 0.024390243902439 1.27341668374667 0.547861691706861 0.696841625416621 GO:0042169 SH2 domain binding 1/357 41/18639 0.024390243902439 1.27341668374667 0.547861691706861 0.696841625416621 GO:0016407 acetyltransferase activity 2/357 96/18639 0.0208333333333333 1.08771008403361 0.55158284003365 0.700345987783531 GO:0004402 histone acetyltransferase activity 1/357 42/18639 0.0238095238095238 1.24309723889556 0.556540763438265 0.702947828384568 GO:0008307 structural constituent of muscle 1/357 42/18639 0.0238095238095238 1.24309723889556 0.556540763438265 0.702947828384568 GO:0031492 nucleosomal DNA binding 1/357 42/18639 0.0238095238095238 1.24309723889556 0.556540763438265 0.702947828384568 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/357 43/18639 0.0232558139534884 1.21418800078171 0.565053692806041 0.712459003972835 GO:0005506 iron ion binding 3/357 154/18639 0.0194805194805195 1.01707955909637 0.568409557150567 0.715446057177362 GO:0043014 alpha-tubulin binding 1/357 44/18639 0.0227272727272727 1.18659281894576 0.573403651488997 0.720481191212344 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/357 45/18639 0.0222222222222222 1.16022408963585 0.581593750785497 0.726992188481872 GO:0051539 4 iron, 4 sulfur cluster binding 1/357 45/18639 0.0222222222222222 1.16022408963585 0.581593750785497 0.726992188481872 GO:0140303 intramembrane lipid transporter activity 1/357 45/18639 0.0222222222222222 1.16022408963585 0.581593750785497 0.726992188481872 GO:0015171 amino acid transmembrane transporter activity 2/357 102/18639 0.0196078431372549 1.02372713791399 0.584573095752041 0.729458682306763 GO:0008514 organic anion transmembrane transporter activity 5/357 269/18639 0.0185873605947955 0.97044765861735 0.589113577794249 0.732317573707879 GO:0004722 protein serine/threonine phosphatase activity 2/357 103/18639 0.0194174757281553 1.01378803948764 0.58989443178676 0.732317573707879 GO:0005253 monoatomic anion channel activity 2/357 103/18639 0.0194174757281553 1.01378803948764 0.58989443178676 0.732317573707879 GO:0005504 fatty acid binding 1/357 47/18639 0.0212765957446809 1.11085285177901 0.597506521366489 0.73547067570578 GO:0061733 protein-lysine-acetyltransferase activity 1/357 47/18639 0.0212765957446809 1.11085285177901 0.597506521366489 0.73547067570578 GO:0061749 forked DNA-dependent helicase activity 1/357 47/18639 0.0212765957446809 1.11085285177901 0.597506521366489 0.73547067570578 GO:0099095 ligand-gated monoatomic anion channel activity 1/357 47/18639 0.0212765957446809 1.11085285177901 0.597506521366489 0.73547067570578 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/357 47/18639 0.0212765957446809 1.11085285177901 0.597506521366489 0.73547067570578 GO:0004866 endopeptidase inhibitor activity 3/357 161/18639 0.0186335403726708 0.972858708700872 0.598594895840068 0.735561524549236 GO:0009378 four-way junction helicase activity 1/357 48/18639 0.0208333333333333 1.08771008403361 0.605235123554105 0.737859850428934 GO:0036121 double-stranded DNA helicase activity 1/357 48/18639 0.0208333333333333 1.08771008403361 0.605235123554105 0.737859850428934 GO:0038187 pattern recognition receptor activity 1/357 48/18639 0.0208333333333333 1.08771008403361 0.605235123554105 0.737859850428934 GO:0043138 3'-5' DNA helicase activity 1/357 48/18639 0.0208333333333333 1.08771008403361 0.605235123554105 0.737859850428934 GO:0000149 SNARE binding 2/357 106/18639 0.0188679245283019 0.985095925162518 0.605553946214091 0.737859850428934 GO:0008017 microtubule binding 5/357 276/18639 0.0181159420289855 0.945834855681403 0.611857412290415 0.744206707708123 GO:0035254 glutamate receptor binding 1/357 49/18639 0.0204081632653061 1.06551191905334 0.61281573034724 0.744206707708123 GO:0016874 ligase activity 3/357 167/18639 0.0179640718562874 0.937905701202637 0.623346811694226 0.755729830231294 GO:0003743 translation initiation factor activity 1/357 51/18639 0.0196078431372549 1.02372713791399 0.627544208580879 0.758282585368562 GO:0016830 carbon-carbon lyase activity 1/357 51/18639 0.0196078431372549 1.02372713791399 0.627544208580879 0.758282585368562 GO:0030414 peptidase inhibitor activity 3/357 169/18639 0.0177514792899408 0.926806225448759 0.631362638269616 0.761627142671334 GO:0005544 calcium-dependent phospholipid binding 1/357 53/18639 0.0188679245283019 0.985095925162518 0.641713925641292 0.769301746771397 GO:0008146 sulfotransferase activity 1/357 53/18639 0.0188679245283019 0.985095925162518 0.641713925641292 0.769301746771397 GO:0034212 protein N-acetyltransferase activity 1/357 53/18639 0.0188679245283019 0.985095925162518 0.641713925641292 0.769301746771397 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/357 229/18639 0.0174672489082969 0.911966533338226 0.641969043857511 0.769301746771397 GO:0000287 magnesium ion binding 4/357 230/18639 0.0173913043478261 0.908001461454147 0.645348310906857 0.770872160441886 GO:0003925 G protein activity 1/357 54/18639 0.0185185185185185 0.966853408029879 0.648595886716621 0.770872160441886 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/357 54/18639 0.0185185185185185 0.966853408029879 0.648595886716621 0.770872160441886 GO:0017069 snRNA binding 1/357 54/18639 0.0185185185185185 0.966853408029879 0.648595886716621 0.770872160441886 GO:0051287 NAD binding 1/357 54/18639 0.0185185185185185 0.966853408029879 0.648595886716621 0.770872160441886 GO:0008374 O-acyltransferase activity 1/357 55/18639 0.0181818181818182 0.949274255156608 0.655346022226019 0.777620075472772 GO:0004175 endopeptidase activity 7/357 405/18639 0.0172839506172839 0.90239651416122 0.660766056793132 0.782770247018007 GO:0170055 lipid transmembrane transporter activity 1/357 56/18639 0.0178571428571429 0.932322929171669 0.66196685036126 0.782913485337542 GO:0005319 lipid transporter activity 3/357 178/18639 0.0168539325842697 0.879945236521575 0.665961836031629 0.786355588148096 GO:0017116 single-stranded DNA helicase activity 1/357 58/18639 0.0172413793103448 0.900173862648508 0.674830418334054 0.795531793971039 GO:0001786 phosphatidylserine binding 1/357 59/18639 0.0169491525423729 0.884916678535821 0.681077958329465 0.798114985873237 GO:0036002 pre-mRNA binding 1/357 59/18639 0.0169491525423729 0.884916678535821 0.681077958329465 0.798114985873237 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/357 122/18639 0.0163934426229508 0.855903016944483 0.681425070697288 0.798114985873237 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/357 122/18639 0.0163934426229508 0.855903016944483 0.681425070697288 0.798114985873237 GO:0061135 endopeptidase regulator activity 3/357 184/18639 0.016304347826087 0.851251370113263 0.687683550051404 0.802932584964843 GO:0004857 enzyme inhibitor activity 7/357 416/18639 0.0168269230769231 0.878535067873303 0.687753290018162 0.802932584964843 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/357 61/18639 0.0163934426229508 0.855903016944483 0.693216209738436 0.806712282600908 GO:0019905 syntaxin binding 1/357 61/18639 0.0163934426229508 0.855903016944483 0.693216209738436 0.806712282600908 GO:0033218 amide binding 4/357 247/18639 0.0161943319838057 0.845507433742728 0.699544478903243 0.812772030777005 GO:0004519 endonuclease activity 2/357 127/18639 0.015748031496063 0.82220604777344 0.702558576705753 0.813770617568328 GO:0022824 transmitter-gated monoatomic ion channel activity 1/357 63/18639 0.0158730158730159 0.828731492597039 0.704893721148841 0.813770617568328 GO:0022835 transmitter-gated channel activity 1/357 63/18639 0.0158730158730159 0.828731492597039 0.704893721148841 0.813770617568328 GO:1901682 sulfur compound transmembrane transporter activity 1/357 63/18639 0.0158730158730159 0.828731492597039 0.704893721148841 0.813770617568328 GO:0016298 lipase activity 2/357 130/18639 0.0153846153846154 0.803232062055592 0.714671769856573 0.82374727050241 GO:0120013 lipid transfer activity 1/357 65/18639 0.0153846153846154 0.803232062055592 0.716127933925992 0.824115479518007 GO:0008235 metalloexopeptidase activity 1/357 66/18639 0.0151515151515152 0.791061879297174 0.721584073023032 0.828835294343856 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/357 132/18639 0.0151515151515152 0.791061879297174 0.722515732448713 0.828835294343856 GO:0050840 extracellular matrix binding 1/357 67/18639 0.0149253731343284 0.77925498557632 0.726935630979785 0.832588202938933 GO:0005548 phospholipid transporter activity 1/357 68/18639 0.0147058823529412 0.767795353435492 0.732184606843463 0.834644402455205 GO:0030145 manganese ion binding 1/357 68/18639 0.0147058823529412 0.767795353435492 0.732184606843463 0.834644402455205 GO:1990841 promoter-specific chromatin binding 1/357 68/18639 0.0147058823529412 0.767795353435492 0.732184606843463 0.834644402455205 GO:0005525 GTP binding 6/357 378/18639 0.0158730158730159 0.828731492597039 0.734182994104847 0.835608588266898 GO:0008080 N-acetyltransferase activity 1/357 69/18639 0.0144927536231884 0.756667884545122 0.73733296155548 0.837878365403955 GO:0016782 transferase activity, transferring sulphur-containing groups 1/357 70/18639 0.0142857142857143 0.745858343337335 0.742382618675819 0.84229639834111 GO:0070851 growth factor receptor binding 2/357 139/18639 0.0143884892086331 0.751224230699474 0.748549907428988 0.8479666920094 GO:0004521 RNA endonuclease activity 1/357 73/18639 0.0136986301369863 0.715206630597444 0.756958094194168 0.854820277711483 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/357 73/18639 0.0136986301369863 0.715206630597444 0.756958094194168 0.854820277711483 GO:0020037 heme binding 2/357 142/18639 0.0140845070422535 0.735353296248077 0.759050848686443 0.855850490354077 GO:0003678 DNA helicase activity 1/357 74/18639 0.0135135135135135 0.705541676129911 0.761631473509728 0.856097392704733 GO:0003684 damaged DNA binding 1/357 74/18639 0.0135135135135135 0.705541676129911 0.761631473509728 0.856097392704733 GO:0003725 double-stranded RNA binding 1/357 75/18639 0.0133333333333333 0.696134453781513 0.766215236717755 0.858587398176774 GO:0044183 protein folding chaperone 1/357 75/18639 0.0133333333333333 0.696134453781513 0.766215236717755 0.858587398176774 GO:0008194 UDP-glycosyltransferase activity 2/357 145/18639 0.0137931034482759 0.720139090118806 0.769171039031125 0.86056944953328 GO:0051536 iron-sulfur cluster binding 1/357 76/18639 0.0131578947368421 0.686974789915966 0.770711097550106 0.860963860899579 GO:0051540 metal cluster binding 1/357 77/18639 0.012987012987013 0.678053039397577 0.775120737057439 0.864557745179451 GO:0019001 guanyl nucleotide binding 6/357 400/18639 0.015 0.783151260504202 0.781376391792033 0.868322007933737 GO:0032561 guanyl ribonucleotide binding 6/357 400/18639 0.015 0.783151260504202 0.781376391792033 0.868322007933737 GO:0008509 monoatomic anion transmembrane transporter activity 2/357 149/18639 0.0134228187919463 0.700806497095482 0.782088649904456 0.868322007933737 GO:0033293 monocarboxylic acid binding 1/357 79/18639 0.0126582278481013 0.660887139665993 0.783687916610962 0.868767185845486 GO:0048306 calcium-dependent protein binding 1/357 80/18639 0.0125 0.652626050420168 0.787848660887357 0.872046227699746 GO:0046906 tetrapyrrole binding 2/357 152/18639 0.0131578947368421 0.686974789915966 0.791357305348794 0.874594582893104 GO:0003774 cytoskeletal motor activity 2/357 153/18639 0.0130718954248366 0.682484758609326 0.79436885460944 0.876586635604024 GO:0005254 chloride channel activity 1/357 83/18639 0.0120481927710843 0.629037157031487 0.799858101453771 0.879965286121372 GO:0008135 translation factor activity, RNA binding 1/357 83/18639 0.0120481927710843 0.629037157031487 0.799858101453771 0.879965286121372 GO:0015291 secondary active transmembrane transporter activity 4/357 287/18639 0.0139372822299652 0.727666676426668 0.802881829274435 0.881526121816559 GO:0180051 translation factor activity 1/357 84/18639 0.0119047619047619 0.621548619447779 0.80370864347689 0.881526121816559 GO:0061134 peptidase regulator activity 3/357 226/18639 0.0132743362831858 0.693054212835577 0.810729372408714 0.887883376127368 GO:0015081 sodium ion transmembrane transporter activity 2/357 164/18639 0.0121951219512195 0.636708341873335 0.825040944968143 0.902194095176325 GO:0072341 modified amino acid binding 1/357 91/18639 0.010989010989011 0.573737187182565 0.8286711713524 0.904799095226641 GO:0052689 carboxylic ester hydrolase activity 1/357 92/18639 0.0108695652173913 0.567500913408842 0.831968798688349 0.907033652705343 GO:0016410 N-acyltransferase activity 1/357 94/18639 0.0106382978723404 0.555426425889505 0.83837537623626 0.912645867524458 GO:0030594 neurotransmitter receptor activity 1/357 97/18639 0.0103092783505155 0.538248289006324 0.847531379329151 0.921229760140382 GO:0005249 voltage-gated potassium channel activity 1/357 98/18639 0.0102040816326531 0.532755959526668 0.850466947098512 0.922825779808587 GO:0003735 structural constituent of ribosome 2/357 175/18639 0.0114285714285714 0.596686674669868 0.851545443713027 0.922825779808587 GO:0043021 ribonucleoprotein complex binding 2/357 177/18639 0.0112994350282486 0.589944452357214 0.855953449930563 0.926218285372624 GO:0008238 exopeptidase activity 1/357 102/18639 0.00980392156862745 0.511863568956994 0.861656258885756 0.930007012161361 GO:0005216 monoatomic ion channel activity 6/357 448/18639 0.0133928571428571 0.699242196878751 0.862020292651634 0.930007012161361 GO:0008237 metallopeptidase activity 2/357 184/18639 0.0108695652173913 0.567500913408842 0.870457481169352 0.937040036856347 GO:0004497 monooxygenase activity 1/357 106/18639 0.00943396226415094 0.492547962581259 0.872010462170577 0.937040036856347 GO:0015078 proton transmembrane transporter activity 2/357 185/18639 0.0108108108108108 0.564433340903929 0.872416586038668 0.937040036856347 GO:0015276 ligand-gated monoatomic ion channel activity 2/357 186/18639 0.010752688172043 0.561398753049607 0.874348446051492 0.937725774241615 GO:0022834 ligand-gated channel activity 2/357 188/18639 0.0106382978723404 0.555426425889505 0.878131714049639 0.938832982254336 GO:0140597 protein carrier chaperone 2/357 188/18639 0.0106382978723404 0.555426425889505 0.878131714049639 0.938832982254336 GO:0004620 phospholipase activity 1/357 109/18639 0.00917431192660551 0.478991596638655 0.879265648207854 0.938832982254336 GO:0004222 metalloendopeptidase activity 1/357 110/18639 0.00909090909090909 0.474637127578304 0.881591722875409 0.939932351595105 GO:0043022 ribosome binding 1/357 112/18639 0.00892857142857143 0.466161464585834 0.886110655009085 0.943363032131552 GO:0016758 hexosyltransferase activity 2/357 197/18639 0.0101522842639594 0.530051614554451 0.893890950699485 0.950250644072033 GO:0017171 serine hydrolase activity 2/357 198/18639 0.0101010101010101 0.527374586198116 0.895520257591984 0.950588853227215 GO:0015108 chloride transmembrane transporter activity 1/357 121/18639 0.00826446280991736 0.431488297798458 0.90440945409013 0.958621131893778 GO:0030246 carbohydrate binding 3/357 280/18639 0.0107142857142857 0.559393757503001 0.906639232178051 0.959581669093557 GO:0005267 potassium channel activity 1/357 124/18639 0.00806451612903226 0.421049064787205 0.909832382464085 0.961557547064813 GO:0005262 calcium channel activity 1/357 131/18639 0.00763358778625954 0.398550259798576 0.921322423227281 0.97087028610433 GO:0031072 heat shock protein binding 1/357 131/18639 0.00763358778625954 0.398550259798576 0.921322423227281 0.97087028610433 GO:0046982 protein heterodimerization activity 4/357 369/18639 0.010840108401084 0.565962970554075 0.925646458174191 0.972748502775681 GO:0051087 protein-folding chaperone binding 1/357 134/18639 0.00746268656716418 0.38962749278816 0.925788230227889 0.972748502775681 GO:0022843 voltage-gated monoatomic cation channel activity 1/357 143/18639 0.00699300699300699 0.365105482752542 0.937725063455734 0.979840024466237 GO:0140098 catalytic activity, acting on RNA 4/357 387/18639 0.0103359173126615 0.539639111458537 0.940938891609901 0.979840024466237 GO:0015085 calcium ion transmembrane transporter activity 1/357 147/18639 0.00680272108843537 0.355170639684445 0.942396003302913 0.979840024466237 GO:0022836 gated channel activity 3/357 318/18639 0.00943396226415094 0.492547962581259 0.945048415887601 0.979840024466237 GO:0019842 vitamin binding 1/357 150/18639 0.00666666666666667 0.348067226890756 0.945668429964502 0.979840024466237 GO:0000510 H3-H4 histone complex chaperone activity 1/357 151/18639 0.00662251655629139 0.34576214591797 0.946717506199165 0.979840024466237 GO:0140584 chromatin extrusion motor activity 1/357 151/18639 0.00662251655629139 0.34576214591797 0.946717506199165 0.979840024466237 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/357 151/18639 0.00662251655629139 0.34576214591797 0.946717506199165 0.979840024466237 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/357 151/18639 0.00662251655629139 0.34576214591797 0.946717506199165 0.979840024466237 GO:0015616 DNA translocase activity 1/357 152/18639 0.00657894736842105 0.343487394957983 0.947746381701485 0.979840024466237 GO:0140674 ATP-dependent histone chaperone activity 1/357 152/18639 0.00657894736842105 0.343487394957983 0.947746381701485 0.979840024466237 GO:0061775 cohesin loader activity 1/357 153/18639 0.0065359477124183 0.341242379304663 0.948755444379722 0.979840024466237 GO:0004386 helicase activity 1/357 155/18639 0.00645161290322581 0.336839251829764 0.950715645897345 0.980467771373507 GO:0140658 ATP-dependent chromatin remodeler activity 1/357 158/18639 0.00632911392405063 0.330443569832996 0.953516630086483 0.980520582083844 GO:0003689 DNA clamp loader activity 1/357 160/18639 0.00625 0.326313025210084 0.95529518359041 0.980520582083844 GO:0015079 potassium ion transmembrane transporter activity 1/357 160/18639 0.00625 0.326313025210084 0.95529518359041 0.980520582083844 GO:0140713 histone chaperone activity 1/357 164/18639 0.00609756097560976 0.318354170936667 0.958651269540712 0.980520582083844 GO:0015103 inorganic anion transmembrane transporter activity 1/357 165/18639 0.00606060606060606 0.316424751718869 0.959450268012916 0.980520582083844 GO:0016887 ATP hydrolysis activity 4/357 417/18639 0.00959232613908873 0.500816153799649 0.960197817990079 0.980520582083844 GO:0005261 monoatomic cation channel activity 3/357 341/18639 0.00879765395894428 0.459326252495133 0.960555489795644 0.980520582083844 GO:0005244 voltage-gated monoatomic ion channel activity 1/357 173/18639 0.00578034682080925 0.301792393257881 0.965312118717168 0.980520582083844 GO:0016757 glycosyltransferase activity 2/357 267/18639 0.00749063670411985 0.391086771787367 0.965335587030314 0.980520582083844 GO:0003823 antigen binding 1/357 174/18639 0.00574712643678161 0.300057954216169 0.965982733556222 0.980520582083844 GO:0022832 voltage-gated channel activity 1/357 175/18639 0.00571428571428571 0.298343337334934 0.966640419130034 0.980520582083844 GO:0004252 serine-type endopeptidase activity 1/357 176/18639 0.00568181818181818 0.29664820473644 0.967285424024454 0.980520582083844 GO:0045182 translation regulator activity 3/357 356/18639 0.00842696629213483 0.439972618260787 0.968348602444183 0.980520582083844 GO:0016853 isomerase activity 1/357 180/18639 0.00555555555555556 0.290056022408964 0.969743443607933 0.980563454136334 GO:0031406 carboxylic acid binding 1/357 187/18639 0.0053475935828877 0.279198310340179 0.973610054894837 0.981043230887488 GO:0046873 metal ion transmembrane transporter activity 4/357 450/18639 0.00888888888888889 0.464089635854342 0.974579198985427 0.981043230887488 GO:0043177 organic acid binding 1/357 189/18639 0.00529100529100529 0.27624383086568 0.97462136232496 0.981043230887488 GO:0022804 active transmembrane transporter activity 4/357 457/18639 0.0087527352297593 0.456981041869702 0.976926222422303 0.981043230887488 GO:0008236 serine-type peptidase activity 1/357 194/18639 0.00515463917525773 0.269124144503162 0.976983741656229 0.981043230887488 GO:0001664 G protein-coupled receptor binding 2/357 297/18639 0.00673400673400673 0.35158305746541 0.978921063359428 0.98162900544341 GO:0008094 ATP-dependent activity, acting on DNA 1/357 210/18639 0.00476190476190476 0.248619447779112 0.983166703889487 0.984524668950108 GO:0140097 catalytic activity, acting on DNA 2/357 336/18639 0.00595238095238095 0.31077430972389 0.98909524452149 0.98909524452149