ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0141003 histone H2AX kinase activity 34/626 354/18639 0.096045197740113 2.85972274868685 4.10418374158731e-08 1.83722697897373e-05 GO:0140996 histone H3 kinase activity 34/626 357/18639 0.0952380952380952 2.83569146508444 5.04534917650856e-08 1.83722697897373e-05 GO:0035173 histone kinase activity 34/626 360/18639 0.0944444444444444 2.8120607028754 6.18594942415399e-08 1.83722697897373e-05 GO:0030695 GTPase regulator activity 40/626 489/18639 0.081799591002045 2.43556322154491 2.15422796831267e-07 3.00991294049313e-05 GO:0060589 nucleoside-triphosphatase regulator activity 40/626 490/18639 0.0816326530612245 2.43059268435809 2.27283824286077e-07 3.00991294049313e-05 GO:0140857 histone H3T45 kinase activity 26/626 246/18639 0.105691056910569 3.14692589417907 2.57313534479347e-07 3.00991294049313e-05 GO:0004679 AMP-activated protein kinase activity 26/626 248/18639 0.104838709677419 3.12154745954859 3.01659903970249e-07 3.00991294049313e-05 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 25/626 243/18639 0.102880658436214 3.06324695302331 7.24850273567282e-07 3.00991294049313e-05 GO:0004676 3-phosphoinositide-dependent protein kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0004711 ribosomal protein S6 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0035175 histone H3S10 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0035979 histone H2AXS139 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0044022 histone H3S28 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0044023 histone H4S1 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0044024 histone H2AS1 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0044025 histone H2BS14 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0072354 histone H3T3 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0072371 histone H2AS121 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0072518 Rho-dependent protein serine/threonine kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0140823 histone H2BS36 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0140855 histone H3S57 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0140995 histone H2A kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0140997 histone H4 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0140998 histone H2B kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:1990244 histone H2AT120 kinase activity 25/626 245/18639 0.102040816326531 3.03824085544761 8.44532250418947e-07 3.00991294049313e-05 GO:0004677 DNA-dependent protein kinase activity 25/626 246/18639 0.101626016260163 3.02589028286449 9.10959706973202e-07 3.12178884197355e-05 GO:0035402 histone H3T11 kinase activity 25/626 247/18639 0.101214574898785 3.01363971491767 9.82163307619664e-07 3.12538395388972e-05 GO:0035403 histone H3T6 kinase activity 25/626 247/18639 0.101214574898785 3.01363971491767 9.82163307619664e-07 3.12538395388972e-05 GO:0005096 GTPase activator activity 26/626 271/18639 0.0959409594095941 2.85661907737288 1.65312429825298e-06 5.07908189566693e-05 GO:0106222 lncRNA binding 8/626 29/18639 0.275862068965517 8.21372700231354 3.55663182101476e-06 0.000105631965084138 GO:0003779 actin binding 34/626 443/18639 0.0767494356659142 2.28519605651274 7.10836986022204e-06 0.000204308307917995 GO:0004674 protein serine/threonine kinase activity 33/626 433/18639 0.0762124711316397 2.26920806617034 1.11955362358865e-05 0.000302657475503851 GO:0031267 small GTPase binding 25/626 283/18639 0.088339222614841 2.63027918581154 1.12095361297723e-05 0.000302657475503851 GO:0106310 protein serine kinase activity 29/626 361/18639 0.0803324099722992 2.39187825794518 1.42874817239315e-05 0.000374416065177147 GO:0051020 GTPase binding 26/626 315/18639 0.0825396825396825 2.45759926973984 2.47564720463452e-05 0.000630229045522673 GO:1990247 N6-methyladenosine-containing RNA reader activity 5/626 12/18639 0.416666666666667 12.4061501597444 2.73742849197696e-05 0.000677513551764296 GO:0001221 transcription coregulator binding 14/626 115/18639 0.121739130434783 3.6247534379775 3.14362446293453e-05 0.000757018755803964 GO:0003712 transcription coregulator activity 32/626 495/18639 0.0646464646464646 1.92483299448156 0.00033333256037795 0.00781577134991455 GO:0070717 poly-purine tract binding 6/626 32/18639 0.1875 5.58276757188498 0.000602244014924586 0.0137589594178925 GO:0140517 protein-RNA adaptor activity 5/626 22/18639 0.227272727272727 6.76699099622422 0.000688580484900414 0.0153381303011567 GO:0005085 guanyl-nucleotide exchange factor activity 18/626 230/18639 0.0782608695652174 2.33019863869982 0.000797355952889148 0.0173279061957129 GO:0045296 cadherin binding 23/626 334/18639 0.0688622754491018 2.05035775095177 0.000963565337083381 0.0199744583311414 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 4/626 14/18639 0.285714285714286 8.50707439525331 0.000963974981188641 0.0199744583311414 GO:0001222 transcription corepressor binding 7/626 49/18639 0.142857142857143 4.25353719762665 0.00117494256033425 0.0237925868467685 GO:0003714 transcription corepressor activity 16/626 204/18639 0.0784313725490196 2.33527532418718 0.00149068146360017 0.0295154929792833 GO:0008143 poly(A) binding 5/626 26/18639 0.192307692307692 5.72591545834357 0.00153940038154797 0.0298175160860704 GO:0016791 phosphatase activity 19/626 273/18639 0.0695970695970696 2.07223607063863 0.0022861665117448 0.0433398800418004 GO:0070566 adenylyltransferase activity 5/626 30/18639 0.166666666666667 4.96246006389776 0.00298595715554976 0.0534720038335949 GO:0003727 single-stranded RNA binding 9/626 89/18639 0.101123595505618 3.01093082528628 0.00299103587299152 0.0534720038335949 GO:0008013 beta-catenin binding 10/626 106/18639 0.0943396226415094 2.80893965881006 0.00300067361580218 0.0534720038335949 GO:0061980 regulatory RNA binding 7/626 58/18639 0.120689655172414 3.59350556351217 0.0031728292914586 0.0554311940919533 GO:0035064 methylated histone binding 8/626 74/18639 0.108108108108108 3.21889301442017 0.00332140502811962 0.0569109976933573 GO:0140034 methylation-dependent protein binding 8/626 76/18639 0.105263157894737 3.13418530351438 0.00392034172508008 0.0659061222084217 GO:0051010 microtubule plus-end binding 4/626 21/18639 0.19047619047619 5.67138293016887 0.00478247877664253 0.0789108998146018 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/626 34/18639 0.147058823529412 4.37864123285097 0.00522233489698209 0.0846018253311099 GO:0016755 aminoacyltransferase activity 28/626 496/18639 0.0564516129032258 1.68083324744924 0.00537742087125367 0.0848153239499752 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/626 22/18639 0.181818181818182 5.41359279697938 0.00569223395258522 0.0848153239499752 GO:0050321 tau-protein kinase activity 4/626 22/18639 0.181818181818182 5.41359279697938 0.00569223395258522 0.0848153239499752 GO:0070034 telomerase RNA binding 4/626 22/18639 0.181818181818182 5.41359279697938 0.00569223395258522 0.0848153239499752 GO:0140030 modification-dependent protein binding 13/626 173/18639 0.0751445086705202 2.23740973979206 0.00571146962626095 0.0848153239499752 GO:0019787 ubiquitin-like protein transferase activity 27/626 479/18639 0.0563674321503132 1.67832678570238 0.0063202907939215 0.0923176901210501 GO:0004535 poly(A)-specific ribonuclease activity 3/626 13/18639 0.230769230769231 6.87109855001229 0.00838270429439946 0.120467573004999 GO:0008139 nuclear localization sequence binding 4/626 25/18639 0.16 4.76396166134185 0.00909253438949788 0.128594414937184 GO:0004842 ubiquitin-protein transferase activity 25/626 449/18639 0.0556792873051225 1.65783743782776 0.00971245573290095 0.13521559465648 GO:0005545 1-phosphatidylinositol binding 3/626 14/18639 0.214285714285714 6.38030579643998 0.0104059941070933 0.1401858639105 GO:0052742 phosphatidylinositol kinase activity 4/626 26/18639 0.153846153846154 4.58073236667486 0.0104658314818524 0.1401858639105 GO:0005496 steroid binding 9/626 108/18639 0.0833333333333333 2.48123003194888 0.0105414734927088 0.1401858639105 GO:0015631 tubulin binding 22/626 385/18639 0.0571428571428571 1.70141487905066 0.0111405002128009 0.143685818508366 GO:0051015 actin filament binding 14/626 209/18639 0.0669856459330144 1.99448155678188 0.0112170641061806 0.143685818508366 GO:0042578 phosphoric ester hydrolase activity 21/626 363/18639 0.0578512396694215 1.72250679903889 0.0113912188909154 0.143685818508366 GO:0001727 lipid kinase activity 5/626 41/18639 0.121951219512195 3.63106833943739 0.0116109752329993 0.143685818508366 GO:0061650 ubiquitin-like protein conjugating enzyme activity 5/626 41/18639 0.121951219512195 3.63106833943739 0.0116109752329993 0.143685818508366 GO:0035198 miRNA binding 5/626 42/18639 0.119047619047619 3.54461433135554 0.0128253165239464 0.155085476741969 GO:0003725 double-stranded RNA binding 7/626 75/18639 0.0933333333333333 2.77897763578275 0.0128802752849671 0.155085476741969 GO:0008201 heparin binding 12/626 172/18639 0.0697674418604651 2.0773088639572 0.0134891338646345 0.160250910311858 GO:0048156 tau protein binding 5/626 43/18639 0.116279069767442 3.46218143992867 0.0141226649360202 0.165516208299063 GO:0140297 DNA-binding transcription factor binding 26/626 488/18639 0.0532786885245902 1.58636018436076 0.0143038698530055 0.165516208299063 GO:0061659 ubiquitin-like protein ligase activity 21/626 372/18639 0.0564516129032258 1.68083324744924 0.014655120533652 0.167406569172871 GO:0035401 histone H3Y41 kinase activity 9/626 115/18639 0.0782608695652174 2.33019863869982 0.0154531000552868 0.170558379432125 GO:0140801 histone H2AXY142 kinase activity 9/626 115/18639 0.0782608695652174 2.33019863869982 0.0154531000552868 0.170558379432125 GO:0001223 transcription coactivator binding 5/626 44/18639 0.113636363636364 3.38349549811211 0.0155053072211023 0.170558379432125 GO:0035091 phosphatidylinositol binding 17/626 284/18639 0.0598591549295775 1.78229199478018 0.0158588706525552 0.172320167700325 GO:0061630 ubiquitin protein ligase activity 20/626 353/18639 0.056657223796034 1.68695526251482 0.0163508983250585 0.175525908525627 GO:0046332 SMAD binding 7/626 79/18639 0.0886075949367089 2.63826990738868 0.0167906441686785 0.178100761360625 GO:0008187 poly-pyrimidine tract binding 4/626 30/18639 0.133333333333333 3.96996805111821 0.0172688880539449 0.178913712279824 GO:0051721 protein phosphatase 2A binding 4/626 30/18639 0.133333333333333 3.96996805111821 0.0172688880539449 0.178913712279824 GO:0043130 ubiquitin binding 8/626 100/18639 0.08 2.38198083067093 0.0193290693588818 0.197956331020273 GO:0004713 protein tyrosine kinase activity 10/626 140/18639 0.0714285714285714 2.12676859881333 0.0198132016452055 0.200608666657706 GO:0022851 GABA-gated chloride ion channel activity 3/626 18/18639 0.166666666666667 4.96246006389776 0.02112163913046 0.210538986680055 GO:0051059 NF-kappaB binding 4/626 32/18639 0.125 3.72184504792332 0.0215028594701291 0.210538986680055 GO:0140142 nucleocytoplasmic carrier activity 4/626 32/18639 0.125 3.72184504792332 0.0215028594701291 0.210538986680055 GO:0140693 molecular condensate scaffold activity 5/626 48/18639 0.104166666666667 3.1015375399361 0.0219306589310625 0.21239366421279 GO:0019903 protein phosphatase binding 10/626 144/18639 0.0694444444444444 2.06769169329073 0.023577801398166 0.225890548879203 GO:0004890 GABA-A receptor activity 3/626 19/18639 0.157894736842105 4.70127795527157 0.0244695141104033 0.228416711445689 GO:0034987 immunoglobulin receptor binding 3/626 19/18639 0.157894736842105 4.70127795527157 0.0244695141104033 0.228416711445689 GO:0008017 microtubule binding 16/626 276/18639 0.0579710144927536 1.72607306570357 0.0246105547685591 0.228416711445689 GO:0003713 transcription coactivator activity 15/626 256/18639 0.05859375 1.74461486621406 0.026630240589419 0.238330306799396 GO:0031625 ubiquitin protein ligase binding 17/626 302/18639 0.0562913907284768 1.67606267058799 0.02688718235665 0.238330306799396 GO:0019902 phosphatase binding 12/626 190/18639 0.0631578947368421 1.88051118210863 0.0270917733242644 0.238330306799396 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 19/626 349/18639 0.0544412607449857 1.62097549365142 0.027209824746143 0.238330306799396 GO:0005048 signal sequence binding 5/626 51/18639 0.0980392156862745 2.91909415523398 0.0277403139266569 0.238330306799396 GO:0019209 kinase activator activity 10/626 148/18639 0.0675675675675676 2.01180813401261 0.0278335182940534 0.238330306799396 GO:0015095 magnesium ion transmembrane transporter activity 3/626 20/18639 0.15 4.46621405750799 0.0280860630908379 0.238330306799396 GO:0052745 inositol phosphate phosphatase activity 3/626 20/18639 0.15 4.46621405750799 0.0280860630908379 0.238330306799396 GO:0061608 nuclear import signal receptor activity 3/626 20/18639 0.15 4.46621405750799 0.0280860630908379 0.238330306799396 GO:0031490 chromatin DNA binding 9/626 128/18639 0.0703125 2.09353783945687 0.0287289229042694 0.241073079557692 GO:0061631 ubiquitin conjugating enzyme activity 4/626 35/18639 0.114285714285714 3.40282975810132 0.0289504147168048 0.241073079557692 GO:0005539 glycosaminoglycan binding 14/626 242/18639 0.0578512396694215 1.72250679903889 0.0345084651580939 0.284694837554275 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/626 38/18639 0.105263157894737 3.13418530351438 0.0377502050400642 0.30577666082452 GO:0042162 telomeric DNA binding 4/626 38/18639 0.105263157894737 3.13418530351438 0.0377502050400642 0.30577666082452 GO:0005319 lipid transporter activity 11/626 178/18639 0.0617977528089888 1.8400132821194 0.0382042650374724 0.306666668003495 GO:0042393 histone binding 14/626 247/18639 0.0566801619433198 1.6876382403539 0.0398929709855053 0.317362831679333 GO:0016917 GABA receptor activity 3/626 23/18639 0.130434782608696 3.88366439783303 0.0405304148219811 0.319580527490134 GO:0005131 growth hormone receptor binding 2/626 10/18639 0.2 5.95495207667732 0.0423840994368727 0.320035869476725 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/626 10/18639 0.2 5.95495207667732 0.0423840994368727 0.320035869476725 GO:0045322 unmethylated CpG binding 2/626 10/18639 0.2 5.95495207667732 0.0423840994368727 0.320035869476725 GO:0070097 delta-catenin binding 2/626 10/18639 0.2 5.95495207667732 0.0423840994368727 0.320035869476725 GO:0140999 histone H3K4 trimethyltransferase activity 2/626 10/18639 0.2 5.95495207667732 0.0423840994368727 0.320035869476725 GO:0019208 phosphatase regulator activity 8/626 117/18639 0.0683760683760684 2.03588105185549 0.0435783690937852 0.326288461029938 GO:0004532 RNA exonuclease activity 4/626 40/18639 0.1 2.97747603833866 0.0443778098018284 0.328548285474883 GO:0030295 protein kinase activator activity 9/626 139/18639 0.0647482014388489 1.92786218309697 0.0449724588525541 0.328548285474883 GO:0044389 ubiquitin-like protein ligase binding 17/626 322/18639 0.0527950310559006 1.57195939912289 0.0449864094589627 0.328548285474883 GO:0019199 transmembrane receptor protein kinase activity 6/626 78/18639 0.0769230769230769 2.29036618333743 0.0470967123900966 0.331982272673724 GO:0070063 RNA polymerase binding 5/626 59/18639 0.0847457627118644 2.5232847782531 0.0476746698243235 0.331982272673724 GO:0017080 sodium channel regulator activity 4/626 41/18639 0.0975609756097561 2.90485467154991 0.0479201702957558 0.331982272673724 GO:1901981 phosphatidylinositol phosphate binding 11/626 185/18639 0.0594594594594595 1.77039115793109 0.0481606789622944 0.331982272673724 GO:0032182 ubiquitin-like protein binding 8/626 120/18639 0.0666666666666667 1.98498402555911 0.0493121583535631 0.331982272673724 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0008432 JUN kinase binding 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0008503 benzodiazepine receptor activity 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0032050 clathrin heavy chain binding 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0034056 estrogen response element binding 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0048185 activin binding 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0097493 structural molecule activity conferring elasticity 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0140537 transcription regulator activator activity 2/626 11/18639 0.181818181818182 5.41359279697938 0.0506729394877963 0.331982272673724 GO:0030507 spectrin binding 3/626 26/18639 0.115384615384615 3.43554927500614 0.0552967120528839 0.357024423471881 GO:0050681 nuclear androgen receptor binding 3/626 26/18639 0.115384615384615 3.43554927500614 0.0552967120528839 0.357024423471881 GO:0016247 channel regulator activity 10/626 168/18639 0.0595238095238095 1.77230716567777 0.0574216777516362 0.360553383695934 GO:0016248 channel inhibitor activity 4/626 44/18639 0.0909090909090909 2.70679639848969 0.0594551041266855 0.360553383695934 GO:0005095 GTPase inhibitor activity 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:0035197 siRNA binding 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:0035497 cAMP response element binding 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:0070410 co-SMAD binding 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:0097677 STAT family protein binding 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:1990817 poly(A) RNA polymerase activity 2/626 12/18639 0.166666666666667 4.96246006389776 0.0594852383875446 0.360553383695934 GO:0008266 poly(U) RNA binding 3/626 27/18639 0.111111111111111 3.30830670926518 0.0607130040361271 0.363055614739525 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/626 27/18639 0.111111111111111 3.30830670926518 0.0607130040361271 0.363055614739525 GO:0141108 transporter regulator activity 10/626 170/18639 0.0588235294117647 1.75145649314039 0.0612067835291013 0.363568294162862 GO:0051117 ATPase binding 6/626 84/18639 0.0714285714285714 2.12676859881333 0.0632390804386497 0.370373345766052 GO:0140303 intramembrane lipid transporter activity 4/626 45/18639 0.0888888888888889 2.64664536741214 0.0635994634143725 0.370373345766052 GO:0141110 transporter inhibitor activity 4/626 45/18639 0.0888888888888889 2.64664536741214 0.0635994634143725 0.370373345766052 GO:0030955 potassium ion binding 2/626 13/18639 0.153846153846154 4.58073236667486 0.068776608222662 0.395354567267044 GO:0070123 transforming growth factor beta receptor activity, type III 2/626 13/18639 0.153846153846154 4.58073236667486 0.068776608222662 0.395354567267044 GO:0035591 signaling adaptor activity 8/626 129/18639 0.062015503875969 1.84649676796196 0.0693511523654401 0.396101774087225 GO:0004721 phosphoprotein phosphatase activity 10/626 175/18639 0.0571428571428571 1.70141487905066 0.0713642791378443 0.405003647845983 GO:0035250 UDP-galactosyltransferase activity 3/626 29/18639 0.103448275862069 3.08014762586758 0.0722516762978042 0.407444579628756 GO:0005543 phospholipid binding 23/626 497/18639 0.0462776659959759 1.37790641613258 0.0762102880664317 0.427065199164721 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/626 48/18639 0.0833333333333333 2.48123003194888 0.0769106608043927 0.428296242354462 GO:0032934 sterol binding 5/626 68/18639 0.0735294117647059 2.18932061642548 0.0781034209418562 0.429128798297876 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/626 14/18639 0.142857142857143 4.25353719762665 0.0785050439085901 0.429128798297876 GO:0046030 inositol trisphosphate phosphatase activity 2/626 14/18639 0.142857142857143 4.25353719762665 0.0785050439085901 0.429128798297876 GO:1901681 sulfur compound binding 14/626 275/18639 0.0509090909090909 1.51580598315423 0.0812467180768145 0.441407474429523 GO:0002020 protease binding 8/626 136/18639 0.0588235294117647 1.75145649314039 0.0879417466826244 0.464458606768797 GO:0140789 histone phosphatase activity 8/626 136/18639 0.0588235294117647 1.75145649314039 0.0879417466826244 0.464458606768797 GO:0000287 magnesium ion binding 12/626 230/18639 0.0521739130434783 1.55346575913321 0.0881515991581415 0.464458606768797 GO:0004559 alpha-mannosidase activity 2/626 15/18639 0.133333333333333 3.96996805111821 0.0886308136182585 0.464458606768797 GO:0005041 low-density lipoprotein particle receptor activity 2/626 15/18639 0.133333333333333 3.96996805111821 0.0886308136182585 0.464458606768797 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/626 15/18639 0.133333333333333 3.96996805111821 0.0886308136182585 0.464458606768797 GO:0005516 calmodulin binding 11/626 207/18639 0.0531400966183575 1.58223364356161 0.09035976670806 0.464458606768797 GO:0099106 ion channel regulator activity 9/626 160/18639 0.05625 1.6748302715655 0.0907326322211991 0.464458606768797 GO:0016922 nuclear receptor binding 8/626 137/18639 0.0583941605839416 1.73867213917586 0.0908128664236513 0.464458606768797 GO:0008378 galactosyltransferase activity 3/626 32/18639 0.09375 2.79138378594249 0.0912236320814135 0.464458606768797 GO:0120015 sterol transfer activity 3/626 32/18639 0.09375 2.79138378594249 0.0912236320814135 0.464458606768797 GO:0043539 protein serine/threonine kinase activator activity 5/626 73/18639 0.0684931506849315 2.03936714954703 0.0986133309274349 0.47736579077381 GO:0004708 MAP kinase kinase activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0005024 transforming growth factor beta receptor activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0008142 oxysterol binding 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0015562 efflux transmembrane transporter activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0015923 mannosidase activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0034450 ubiquitin-ubiquitin ligase activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0140327 flippase activity 2/626 16/18639 0.125 3.72184504792332 0.0991163538643714 0.47736579077381 GO:0005003 ephrin receptor activity 4/626 53/18639 0.0754716981132075 2.24715172704804 0.101900960008249 0.482945507273139 GO:0005005 transmembrane-ephrin receptor activity 4/626 53/18639 0.0754716981132075 2.24715172704804 0.101900960008249 0.482945507273139 GO:0051018 protein kinase A binding 4/626 53/18639 0.0754716981132075 2.24715172704804 0.101900960008249 0.482945507273139 GO:0030332 cyclin binding 3/626 34/18639 0.0882352941176471 2.62718473971058 0.104895466463682 0.494507199043071 GO:0008429 phosphatidylethanolamine binding 2/626 17/18639 0.117647058823529 3.50291298628077 0.109926169047162 0.512796945659797 GO:1990226 histone methyltransferase binding 2/626 17/18639 0.117647058823529 3.50291298628077 0.109926169047162 0.512796945659797 GO:0000175 3'-5'-RNA exonuclease activity 3/626 35/18639 0.0857142857142857 2.55212231857599 0.112015315064951 0.517489141008361 GO:0098631 cell adhesion mediator activity 5/626 76/18639 0.0657894736842105 1.95886581469649 0.112093607423809 0.517489141008361 GO:0003697 single-stranded DNA binding 7/626 121/18639 0.0578512396694215 1.72250679903889 0.113169548828346 0.51976323714462 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/626 36/18639 0.0833333333333333 2.48123003194888 0.119313794244209 0.531206015470413 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0017075 syntaxin-1 binding 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0030228 lipoprotein particle receptor activity 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0031690 adrenergic receptor binding 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0050811 GABA receptor binding 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0070064 proline-rich region binding 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:1990381 ubiquitin-specific protease binding 2/626 18/18639 0.111111111111111 3.30830670926518 0.121026735286749 0.531206015470413 GO:0023023 MHC protein complex binding 3/626 37/18639 0.0810810810810811 2.41416976081513 0.12678279766736 0.553742513341265 GO:0030506 ankyrin binding 2/626 19/18639 0.105263157894737 3.13418530351438 0.13238640836632 0.561696618354243 GO:0031420 alkali metal ion binding 2/626 19/18639 0.105263157894737 3.13418530351438 0.13238640836632 0.561696618354243 GO:0042800 histone H3K4 methyltransferase activity 2/626 19/18639 0.105263157894737 3.13418530351438 0.13238640836632 0.561696618354243 GO:0046624 sphingolipid transporter activity 2/626 19/18639 0.105263157894737 3.13418530351438 0.13238640836632 0.561696618354243 GO:0140036 ubiquitin-modified protein reader activity 2/626 19/18639 0.105263157894737 3.13418530351438 0.13238640836632 0.561696618354243 GO:1990380 K48-linked deubiquitinase activity 2/626 19/18639 0.105263157894737 3.13418530351438 0.13238640836632 0.561696618354243 GO:0042277 peptide binding 12/626 249/18639 0.0481927710843374 1.43492821124755 0.134700869617906 0.565249296681636 GO:0019783 ubiquitin-like protein peptidase activity 7/626 127/18639 0.0551181102362205 1.64112852506855 0.135892404647051 0.565249296681636 GO:0004879 nuclear receptor activity 4/626 59/18639 0.0677966101694915 2.01862782260248 0.136110130381287 0.565249296681636 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/626 59/18639 0.0677966101694915 2.01862782260248 0.136110130381287 0.565249296681636 GO:0001618 virus receptor activity 5/626 81/18639 0.0617283950617284 1.83794817181399 0.136395733767174 0.565249296681636 GO:0140272 exogenous protein binding 5/626 82/18639 0.0609756097560976 1.81553416971869 0.141516346949318 0.578602713462718 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/626 60/18639 0.0666666666666667 1.98498402555911 0.142215481760197 0.578602713462718 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/626 60/18639 0.0666666666666667 1.98498402555911 0.142215481760197 0.578602713462718 GO:0098531 ligand-modulated transcription factor activity 4/626 60/18639 0.0666666666666667 1.98498402555911 0.142215481760197 0.578602713462718 GO:0000149 SNARE binding 6/626 106/18639 0.0566037735849057 1.68536379528603 0.146488443785933 0.591524859121316 GO:0030165 PDZ domain binding 5/626 83/18639 0.0602409638554217 1.79366026405943 0.146719409501471 0.591524859121316 GO:0015026 coreceptor activity 4/626 61/18639 0.0655737704918033 1.95244330382863 0.148427010606351 0.593042450449593 GO:0016836 hydro-lyase activity 4/626 61/18639 0.0655737704918033 1.95244330382863 0.148427010606351 0.593042450449593 GO:0019887 protein kinase regulator activity 12/626 255/18639 0.0470588235294118 1.40116519451231 0.151754462242331 0.600190472553422 GO:0004527 exonuclease activity 5/626 84/18639 0.0595238095238095 1.77230716567777 0.15200297463203 0.600190472553422 GO:0008373 sialyltransferase activity 2/626 21/18639 0.0952380952380952 2.83569146508444 0.155765371599075 0.600190472553422 GO:0035613 RNA stem-loop binding 2/626 21/18639 0.0952380952380952 2.83569146508444 0.155765371599075 0.600190472553422 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/626 21/18639 0.0952380952380952 2.83569146508444 0.155765371599075 0.600190472553422 GO:0061891 calcium ion sensor activity 2/626 21/18639 0.0952380952380952 2.83569146508444 0.155765371599075 0.600190472553422 GO:0004843 cysteine-type deubiquitinase activity 6/626 108/18639 0.0555555555555556 1.65415335463259 0.155782689295957 0.600190472553422 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/626 41/18639 0.0731707317073171 2.17864100366243 0.158200493088374 0.600190472553422 GO:0042169 SH2 domain binding 3/626 41/18639 0.0731707317073171 2.17864100366243 0.158200493088374 0.600190472553422 GO:0004520 DNA endonuclease activity 3/626 42/18639 0.0714285714285714 2.12676859881333 0.1663994259852 0.600190472553422 GO:0048487 beta-tubulin binding 3/626 42/18639 0.0714285714285714 2.12676859881333 0.1663994259852 0.600190472553422 GO:0032931 histone H3K56 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0043992 histone H3K9 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0043993 histone H3K18 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0043994 histone H3K23 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0043999 histone H2AK5 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0044012 histone H2AK9 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0044014 histone H2BK5 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0044015 histone H2BK12 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0044016 histone H3K4 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0044017 histone H3K27 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0044018 histone H3K36 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0046972 histone H4K16 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0140035 ubiquitin-like protein reader activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0140784 metal ion sensor activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0140908 histone H3K122 acetyltransferase activity 2/626 22/18639 0.0909090909090909 2.70679639848969 0.167729997380249 0.600190472553422 GO:0019207 kinase regulator activity 13/626 287/18639 0.0452961672473868 1.34868252607674 0.170335006865579 0.607073964468923 GO:0016779 nucleotidyltransferase activity 7/626 136/18639 0.0514705882352941 1.53252443149784 0.173764571510127 0.610491913243962 GO:0019838 growth factor binding 7/626 136/18639 0.0514705882352941 1.53252443149784 0.173764571510127 0.610491913243962 GO:0044325 transmembrane transporter binding 7/626 136/18639 0.0514705882352941 1.53252443149784 0.173764571510127 0.610491913243962 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/626 43/18639 0.0697674418604651 2.0773088639572 0.174719907830764 0.610491913243962 GO:0008200 ion channel inhibitor activity 3/626 43/18639 0.0697674418604651 2.0773088639572 0.174719907830764 0.610491913243962 GO:0017134 fibroblast growth factor binding 2/626 23/18639 0.0869565217391304 2.58910959855535 0.17984424333818 0.621090003156271 GO:0044013 histone H2B acetyltransferase activity 2/626 23/18639 0.0869565217391304 2.58910959855535 0.17984424333818 0.621090003156271 GO:0140103 catalytic activity, acting on a glycoprotein 2/626 23/18639 0.0869565217391304 2.58910959855535 0.17984424333818 0.621090003156271 GO:0019205 nucleobase-containing compound kinase activity 3/626 44/18639 0.0681818181818182 2.03009729886727 0.183153917857891 0.622354153474055 GO:0050840 extracellular matrix binding 4/626 67/18639 0.0597014925373134 1.77759763482905 0.187720136781003 0.622354153474055 GO:0017124 SH3 domain binding 6/626 115/18639 0.0521739130434783 1.55346575913321 0.190226272094027 0.622354153474055 GO:0101005 deubiquitinase activity 6/626 115/18639 0.0521739130434783 1.55346575913321 0.190226272094027 0.622354153474055 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/626 45/18639 0.0666666666666667 1.98498402555911 0.191693521746714 0.622354153474055 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0004622 lysophospholipase activity 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0005315 phosphate transmembrane transporter activity 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0005540 hyaluronic acid binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0030215 semaphorin receptor binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0030552 cAMP binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0043998 histone H2A acetyltransferase activity 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0048027 mRNA 5'-UTR binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0050431 transforming growth factor beta binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0050699 WW domain binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0070840 dynein complex binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0140033 acetylation-dependent protein binding 2/626 24/18639 0.0833333333333333 2.48123003194888 0.19208461526977 0.622354153474055 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 20/626 484/18639 0.0413223140495868 1.2303619993135 0.199862414978106 0.644385627592974 GO:0030276 clathrin binding 3/626 46/18639 0.0652173913043478 1.94183219891652 0.200330885345964 0.644385627592974 GO:0003707 nuclear steroid receptor activity 2/626 25/18639 0.08 2.38198083067093 0.204429023715764 0.651074616830956 GO:0019211 phosphatase activator activity 2/626 25/18639 0.08 2.38198083067093 0.204429023715764 0.651074616830956 GO:0005201 extracellular matrix structural constituent 8/626 168/18639 0.0476190476190476 1.41784573254222 0.204602573190424 0.651074616830956 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/626 70/18639 0.0571428571428571 1.70141487905066 0.208497869053977 0.655883569519853 GO:0099095 ligand-gated monoatomic anion channel activity 3/626 47/18639 0.0638297872340425 1.90051662021616 0.209058287029897 0.655883569519853 GO:0140359 ABC-type transporter activity 3/626 47/18639 0.0638297872340425 1.90051662021616 0.209058287029897 0.655883569519853 GO:0140938 histone H3 methyltransferase activity 3/626 47/18639 0.0638297872340425 1.90051662021616 0.209058287029897 0.655883569519853 GO:0140299 molecular sensor activity 4/626 71/18639 0.0563380281690141 1.67745128920488 0.215565815065409 0.665216822345085 GO:0004435 phosphatidylinositol phospholipase C activity 2/626 26/18639 0.0769230769230769 2.29036618333743 0.216856716354337 0.665216822345085 GO:0005160 transforming growth factor beta receptor binding 2/626 26/18639 0.0769230769230769 2.29036618333743 0.216856716354337 0.665216822345085 GO:0050750 low-density lipoprotein particle receptor binding 2/626 26/18639 0.0769230769230769 2.29036618333743 0.216856716354337 0.665216822345085 GO:0051139 metal cation:proton antiporter activity 2/626 26/18639 0.0769230769230769 2.29036618333743 0.216856716354337 0.665216822345085 GO:0001216 DNA-binding transcription activator activity 20/626 491/18639 0.0407331975560081 1.21282119687929 0.217655964585209 0.665216822345085 GO:0032266 phosphatidylinositol-3-phosphate binding 3/626 48/18639 0.0625 1.86092252396166 0.217868128778264 0.665216822345085 GO:0005518 collagen binding 4/626 72/18639 0.0555555555555556 1.65415335463259 0.22269837115305 0.665216822345085 GO:0005004 GPI-linked ephrin receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0005008 hepatocyte growth factor receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0005009 insulin receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0005011 macrophage colony-stimulating factor receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0005020 stem cell factor receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0008288 boss receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0036332 placental growth factor receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0038062 protein tyrosine kinase collagen receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0060175 brain-derived neurotrophic factor receptor activity 3/626 49/18639 0.0612244897959184 1.82294451326857 0.226752946062063 0.665216822345085 GO:0008395 steroid hydroxylase activity 2/626 27/18639 0.0740740740740741 2.20553780617678 0.229348213339794 0.665216822345085 GO:0023026 MHC class II protein complex binding 2/626 27/18639 0.0740740740740741 2.20553780617678 0.229348213339794 0.665216822345085 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/626 27/18639 0.0740740740740741 2.20553780617678 0.229348213339794 0.665216822345085 GO:0004725 protein tyrosine phosphatase activity 5/626 98/18639 0.0510204081632653 1.51912042772381 0.233238304941286 0.665216822345085 GO:0005006 epidermal growth factor receptor activity 3/626 50/18639 0.06 1.78648562300319 0.235705416613336 0.665216822345085 GO:0005007 fibroblast growth factor receptor activity 3/626 50/18639 0.06 1.78648562300319 0.235705416613336 0.665216822345085 GO:0005017 platelet-derived growth factor receptor activity 3/626 50/18639 0.06 1.78648562300319 0.235705416613336 0.665216822345085 GO:0005019 platelet-derived growth factor beta-receptor activity 3/626 50/18639 0.06 1.78648562300319 0.235705416613336 0.665216822345085 GO:0031491 nucleosome binding 4/626 74/18639 0.0540540540540541 1.60944650721009 0.237142008220207 0.665216822345085 GO:0036408 histone H3K14 acetyltransferase activity 2/626 28/18639 0.0714285714285714 2.12676859881333 0.241885245465281 0.665216822345085 GO:0045499 chemorepellent activity 2/626 28/18639 0.0714285714285714 2.12676859881333 0.241885245465281 0.665216822345085 GO:0046966 nuclear thyroid hormone receptor binding 2/626 28/18639 0.0714285714285714 2.12676859881333 0.241885245465281 0.665216822345085 GO:0051393 alpha-actinin binding 2/626 28/18639 0.0714285714285714 2.12676859881333 0.241885245465281 0.665216822345085 GO:0141052 histone H3 demethylase activity 2/626 28/18639 0.0714285714285714 2.12676859881333 0.241885245465281 0.665216822345085 GO:0005010 insulin-like growth factor receptor activity 3/626 51/18639 0.0588235294117647 1.75145649314039 0.24471836815301 0.665216822345085 GO:0005021 vascular endothelial growth factor receptor activity 3/626 51/18639 0.0588235294117647 1.75145649314039 0.24471836815301 0.665216822345085 GO:0005030 neurotrophin receptor activity 3/626 51/18639 0.0588235294117647 1.75145649314039 0.24471836815301 0.665216822345085 GO:0016597 amino acid binding 3/626 51/18639 0.0588235294117647 1.75145649314039 0.24471836815301 0.665216822345085 GO:0017022 myosin binding 4/626 76/18639 0.0526315789473684 1.56709265175719 0.25179836500581 0.665216822345085 GO:0005080 protein kinase C binding 3/626 52/18639 0.0576923076923077 1.71777463750307 0.253784785146773 0.665216822345085 GO:0003785 actin monomer binding 2/626 29/18639 0.0689655172413793 2.05343175057838 0.254450695033243 0.665216822345085 GO:0004629 phospholipase C activity 2/626 29/18639 0.0689655172413793 2.05343175057838 0.254450695033243 0.665216822345085 GO:0010484 histone H3 acetyltransferase activity 2/626 29/18639 0.0689655172413793 2.05343175057838 0.254450695033243 0.665216822345085 GO:0043236 laminin binding 2/626 29/18639 0.0689655172413793 2.05343175057838 0.254450695033243 0.665216822345085 GO:0038064 collagen receptor activity 3/626 53/18639 0.0566037735849057 1.68536379528603 0.262897814655084 0.665216822345085 GO:0140296 general transcription initiation factor binding 3/626 53/18639 0.0566037735849057 1.68536379528603 0.262897814655084 0.665216822345085 GO:0032452 histone demethylase activity 2/626 30/18639 0.0666666666666667 1.98498402555911 0.267028539321934 0.665216822345085 GO:0043995 histone H4K5 acetyltransferase activity 2/626 30/18639 0.0666666666666667 1.98498402555911 0.267028539321934 0.665216822345085 GO:0043996 histone H4K8 acetyltransferase activity 2/626 30/18639 0.0666666666666667 1.98498402555911 0.267028539321934 0.665216822345085 GO:0043997 histone H4K12 acetyltransferase activity 2/626 30/18639 0.0666666666666667 1.98498402555911 0.267028539321934 0.665216822345085 GO:0003730 mRNA 3'-UTR binding 11/626 262/18639 0.0419847328244275 1.25008535960783 0.267076469019116 0.665216822345085 GO:0015485 cholesterol binding 3/626 54/18639 0.0555555555555556 1.65415335463259 0.272050771339815 0.665216822345085 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/626 54/18639 0.0555555555555556 1.65415335463259 0.272050771339815 0.665216822345085 GO:0017069 snRNA binding 3/626 54/18639 0.0555555555555556 1.65415335463259 0.272050771339815 0.665216822345085 GO:0140463 chromatin-protein adaptor activity 3/626 54/18639 0.0555555555555556 1.65415335463259 0.272050771339815 0.665216822345085 GO:0016835 carbon-oxygen lyase activity 4/626 79/18639 0.0506329113924051 1.50758280422211 0.27411627207216 0.665216822345085 GO:0017147 Wnt-protein binding 2/626 31/18639 0.0645161290322581 1.92095228279913 0.279603796540749 0.665216822345085 GO:0070273 phosphatidylinositol-4-phosphate binding 2/626 31/18639 0.0645161290322581 1.92095228279913 0.279603796540749 0.665216822345085 GO:0070325 lipoprotein particle receptor binding 2/626 31/18639 0.0645161290322581 1.92095228279913 0.279603796540749 0.665216822345085 GO:0140457 protein demethylase activity 2/626 31/18639 0.0645161290322581 1.92095228279913 0.279603796540749 0.665216822345085 GO:0008374 O-acyltransferase activity 3/626 55/18639 0.0545454545454545 1.62407783909381 0.281237141686499 0.665216822345085 GO:0030971 receptor tyrosine kinase binding 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0033192 calmodulin-dependent protein phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0140791 histone H2AXS140 phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/626 81/18639 0.0493827160493827 1.47035853745119 0.289174414529596 0.665216822345085 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0004955 prostaglandin receptor activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0015187 glycine transmembrane transporter activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0015643 toxic substance binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0030957 Tat protein binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0031720 haptoglobin binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0031996 thioesterase binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0042975 peroxisome proliferator activated receptor binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0043121 neurotrophin binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0043208 glycosphingolipid binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0050815 phosphoserine residue binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0051880 G-quadruplex DNA binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0070513 death domain binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0099122 RNA polymerase II C-terminal domain binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:1905394 retromer complex binding 1/626 10/18639 0.1 2.97747603833866 0.289444581530722 0.665216822345085 GO:0019888 protein phosphatase regulator activity 5/626 107/18639 0.0467289719626168 1.39134394314891 0.290742573090317 0.665216822345085 GO:0031406 carboxylic acid binding 8/626 187/18639 0.0427807486631016 1.27378654046574 0.29311060839293 0.665216822345085 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/626 82/18639 0.0487804878048781 1.45242733577496 0.296746623123456 0.665216822345085 GO:0033549 MAP kinase phosphatase activity 4/626 82/18639 0.0487804878048781 1.45242733577496 0.296746623123456 0.665216822345085 GO:0043177 organic acid binding 8/626 189/18639 0.0423280423280423 1.26030731781531 0.30295889254047 0.665216822345085 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/626 83/18639 0.0481927710843374 1.43492821124755 0.304342937737227 0.665216822345085 GO:0005254 chloride channel activity 4/626 83/18639 0.0481927710843374 1.43492821124755 0.304342937737227 0.665216822345085 GO:0019239 deaminase activity 2/626 33/18639 0.0606060606060606 1.80453093232646 0.304691519595843 0.665216822345085 GO:0030296 protein tyrosine kinase activator activity 2/626 33/18639 0.0606060606060606 1.80453093232646 0.304691519595843 0.665216822345085 GO:0140416 transcription regulator inhibitor activity 2/626 33/18639 0.0606060606060606 1.80453093232646 0.304691519595843 0.665216822345085 GO:0008408 3'-5' exonuclease activity 3/626 58/18639 0.0517241379310345 1.54007381293379 0.308934245590031 0.665216822345085 GO:0017018 myosin phosphatase activity 4/626 84/18639 0.0476190476190476 1.41784573254222 0.311959935892487 0.665216822345085 GO:0002162 dystroglycan binding 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0004016 adenylate cyclase activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0004954 prostanoid receptor activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0005114 type II transforming growth factor beta receptor binding 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0005225 volume-sensitive anion channel activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0008172 S-methyltransferase activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0019206 nucleoside kinase activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0050998 nitric-oxide synthase binding 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:0180030 inositol phosphate kinase activity 1/626 11/18639 0.0909090909090909 2.70679639848969 0.313321745735015 0.665216822345085 GO:1902936 phosphatidylinositol bisphosphate binding 5/626 111/18639 0.045045045045045 1.34120542267507 0.317083304541463 0.665216822345085 GO:0015035 protein-disulfide reductase activity 2/626 34/18639 0.0588235294117647 1.75145649314039 0.317178772916603 0.665216822345085 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/626 34/18639 0.0588235294117647 1.75145649314039 0.317178772916603 0.665216822345085 GO:0016831 carboxy-lyase activity 2/626 34/18639 0.0588235294117647 1.75145649314039 0.317178772916603 0.665216822345085 GO:0019825 oxygen binding 2/626 34/18639 0.0588235294117647 1.75145649314039 0.317178772916603 0.665216822345085 GO:0051427 hormone receptor binding 2/626 34/18639 0.0588235294117647 1.75145649314039 0.317178772916603 0.665216822345085 GO:0090482 vitamin transmembrane transporter activity 2/626 34/18639 0.0588235294117647 1.75145649314039 0.317178772916603 0.665216822345085 GO:0015459 potassium channel regulator activity 3/626 59/18639 0.0508474576271186 1.51397086695186 0.318192680333356 0.665216822345085 GO:0031593 polyubiquitin modification-dependent protein binding 3/626 59/18639 0.0508474576271186 1.51397086695186 0.318192680333356 0.665216822345085 GO:0036002 pre-mRNA binding 3/626 59/18639 0.0508474576271186 1.51397086695186 0.318192680333356 0.665216822345085 GO:0045309 protein phosphorylated amino acid binding 3/626 59/18639 0.0508474576271186 1.51397086695186 0.318192680333356 0.665216822345085 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/626 86/18639 0.0465116279069767 1.38487257597147 0.327242576886385 0.665216822345085 GO:0001098 basal transcription machinery binding 3/626 60/18639 0.05 1.48873801916933 0.327454638152996 0.665216822345085 GO:0001099 basal RNA polymerase II transcription machinery binding 3/626 60/18639 0.05 1.48873801916933 0.327454638152996 0.665216822345085 GO:0016887 ATP hydrolysis activity 16/626 417/18639 0.0383693045563549 1.14243684924265 0.32826511479257 0.665216822345085 GO:0005154 epidermal growth factor receptor binding 2/626 35/18639 0.0571428571428571 1.70141487905066 0.329612921877309 0.665216822345085 GO:0005343 organic acid:sodium symporter activity 2/626 35/18639 0.0571428571428571 1.70141487905066 0.329612921877309 0.665216822345085 GO:0010485 histone H4 acetyltransferase activity 2/626 35/18639 0.0571428571428571 1.70141487905066 0.329612921877309 0.665216822345085 GO:0140566 histone reader activity 2/626 35/18639 0.0571428571428571 1.70141487905066 0.329612921877309 0.665216822345085 GO:0004000 adenosine deaminase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005025 transforming growth factor beta receptor activity, type I 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005026 transforming growth factor beta receptor activity, type II 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005049 nuclear export signal receptor activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005078 MAP-kinase scaffold activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005165 neurotrophin receptor binding 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005247 voltage-gated chloride channel activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0005436 sodium:phosphate symporter activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0008179 adenylate cyclase binding 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0008603 cAMP-dependent protein kinase regulator activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0015132 prostaglandin transmembrane transporter activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0016208 AMP binding 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0016361 activin receptor activity, type I 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0016362 activin receptor activity, type II 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0016840 carbon-nitrogen lyase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0017002 activin receptor activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0017166 vinculin binding 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0034452 dynactin binding 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0045295 gamma-catenin binding 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/626 12/18639 0.0833333333333333 2.48123003194888 0.336397791857513 0.665216822345085 GO:0019905 syntaxin binding 3/626 61/18639 0.0491803278688525 1.46433247787147 0.336714687853685 0.665216822345085 GO:0000993 RNA polymerase II complex binding 2/626 36/18639 0.0555555555555556 1.65415335463259 0.341983458796904 0.665836052979024 GO:0004190 aspartic-type endopeptidase activity 2/626 36/18639 0.0555555555555556 1.65415335463259 0.341983458796904 0.665836052979024 GO:0005484 SNAP receptor activity 2/626 36/18639 0.0555555555555556 1.65415335463259 0.341983458796904 0.665836052979024 GO:0004197 cysteine-type endopeptidase activity 4/626 88/18639 0.0454545454545455 1.35339819924484 0.342568332378171 0.665836052979024 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/626 89/18639 0.0449438202247191 1.33819147790502 0.350239457954861 0.665836052979024 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/626 89/18639 0.0449438202247191 1.33819147790502 0.350239457954861 0.665836052979024 GO:0030551 cyclic nucleotide binding 2/626 37/18639 0.0540540540540541 1.60944650721009 0.354280639432877 0.665836052979024 GO:0042805 actinin binding 2/626 37/18639 0.0540540540540541 1.60944650721009 0.354280639432877 0.665836052979024 GO:0070001 aspartic-type peptidase activity 2/626 37/18639 0.0540540540540541 1.60944650721009 0.354280639432877 0.665836052979024 GO:0019955 cytokine binding 6/626 144/18639 0.0416666666666667 1.24061501597444 0.354695023660765 0.665836052979024 GO:0022824 transmitter-gated monoatomic ion channel activity 3/626 63/18639 0.0476190476190476 1.41784573254222 0.355208256420395 0.665836052979024 GO:0022835 transmitter-gated channel activity 3/626 63/18639 0.0476190476190476 1.41784573254222 0.355208256420395 0.665836052979024 GO:1990782 protein tyrosine kinase binding 5/626 117/18639 0.0427350427350427 1.27242565740968 0.357070841079545 0.665836052979024 GO:0140793 histone H2AXY142 phosphatase activity 4/626 90/18639 0.0444444444444444 1.32332268370607 0.357911987636527 0.665836052979024 GO:0016829 lyase activity 8/626 200/18639 0.04 1.19099041533546 0.358218814917184 0.665836052979024 GO:0005542 folic acid binding 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0008417 fucosyltransferase activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0031994 insulin-like growth factor I binding 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0043560 insulin receptor substrate binding 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0045159 myosin II binding 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0046974 histone H3K9 methyltransferase activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0046975 histone H3K36 methyltransferase activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0061459 L-arginine transmembrane transporter activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0071714 icosanoid transmembrane transporter activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0089720 caspase binding 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0097157 pre-mRNA intronic binding 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0140666 annealing activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/626 13/18639 0.0769230769230769 2.29036618333743 0.358699557160417 0.665836052979024 GO:0004536 DNA nuclease activity 3/626 64/18639 0.046875 1.39569189297125 0.364431829938339 0.668156784874951 GO:0043531 ADP binding 2/626 38/18639 0.0526315789473684 1.56709265175719 0.366495443693054 0.668156784874951 GO:0015291 secondary active transmembrane transporter activity 11/626 287/18639 0.0383275261324042 1.14119290668032 0.370723792078578 0.668156784874951 GO:0043178 alcohol binding 4/626 92/18639 0.0434782608695652 1.29455479927768 0.373249378244 0.668156784874951 GO:0038024 cargo receptor activity 3/626 65/18639 0.0461538461538462 1.37421971000246 0.373633602937796 0.668156784874951 GO:0120013 lipid transfer activity 3/626 65/18639 0.0461538461538462 1.37421971000246 0.373633602937796 0.668156784874951 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/626 39/18639 0.0512820512820513 1.52691078889162 0.37861953811843 0.668156784874951 GO:0005161 platelet-derived growth factor receptor binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0005344 oxygen carrier activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0008195 phosphatidate phosphatase activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0008474 palmitoyl-(protein) hydrolase activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0008559 ABC-type xenobiotic transporter activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0015386 potassium:proton antiporter activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0019992 diacylglycerol binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0032454 histone H3K9 demethylase activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0034236 protein kinase A catalytic subunit binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0042813 Wnt receptor activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0043176 amine binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0061665 SUMO ligase activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0070742 C2H2 zinc finger domain binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0071933 Arp2/3 complex binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0098599 palmitoyl hydrolase activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0098821 BMP receptor activity 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:1990825 sequence-specific mRNA binding 1/626 14/18639 0.0714285714285714 2.12676859881333 0.380252981256712 0.668156784874951 GO:0004540 RNA nuclease activity 5/626 121/18639 0.0413223140495868 1.2303619993135 0.383849127315498 0.668156784874951 GO:0043021 ribonucleoprotein complex binding 7/626 177/18639 0.0395480225988701 1.17753289651811 0.384565048463178 0.668156784874951 GO:0042562 hormone binding 4/626 94/18639 0.0425531914893617 1.26701108014411 0.388557430625526 0.668156784874951 GO:0015036 disulfide oxidoreductase activity 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0015144 carbohydrate transmembrane transporter activity 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0032451 demethylase activity 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0050997 quaternary ammonium group binding 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0061791 GTPase motor activity 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0071949 FAD binding 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:1990606 membrane scission GTPase motor activity 2/626 40/18639 0.05 1.48873801916933 0.39064524006273 0.668156784874951 GO:0016500 protein-hormone receptor activity 3/626 67/18639 0.0447761194029851 1.33319822612179 0.391953849317584 0.668156784874951 GO:0042054 histone methyltransferase activity 3/626 67/18639 0.0447761194029851 1.33319822612179 0.391953849317584 0.668156784874951 GO:0008276 protein methyltransferase activity 4/626 95/18639 0.0421052631578947 1.25367412140575 0.396193550486412 0.668156784874951 GO:1990841 promoter-specific chromatin binding 3/626 68/18639 0.0441176470588235 1.31359236985529 0.401063818600505 0.668156784874951 GO:0004089 carbonate dehydratase activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0004953 icosanoid receptor activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0005523 tropomyosin binding 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0017081 chloride channel regulator activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0030553 cGMP binding 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0042809 nuclear vitamin D receptor binding 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0047372 monoacylglycerol lipase activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0048531 beta-1,3-galactosyltransferase activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0051371 muscle alpha-actinin binding 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0061578 K63-linked deubiquitinase activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0120283 protein serine/threonine kinase binding 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0140776 protein-containing complex destabilizing activity 1/626 15/18639 0.0666666666666667 1.98498402555911 0.401083136088029 0.668156784874951 GO:0042287 MHC protein binding 2/626 41/18639 0.0487804878048781 1.45242733577496 0.402565483497313 0.668156784874951 GO:0140828 metal cation:monoatomic cation antiporter activity 2/626 41/18639 0.0487804878048781 1.45242733577496 0.402565483497313 0.668156784874951 GO:0004896 cytokine receptor activity 4/626 96/18639 0.0416666666666667 1.24061501597444 0.403814192645335 0.668156784874951 GO:0016407 acetyltransferase activity 4/626 96/18639 0.0416666666666667 1.24061501597444 0.403814192645335 0.668156784874951 GO:0004518 nuclease activity 8/626 209/18639 0.0382775119617225 1.1397037467325 0.404193610603366 0.668156784874951 GO:0016279 protein-lysine N-methyltransferase activity 3/626 69/18639 0.0434782608695652 1.29455479927768 0.410134975120945 0.672584052183726 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/626 268/18639 0.0373134328358209 1.11099852176816 0.412667172865169 0.672584052183726 GO:0004402 histone acetyltransferase activity 2/626 42/18639 0.0476190476190476 1.41784573254222 0.414373786372919 0.672584052183726 GO:0008307 structural constituent of muscle 2/626 42/18639 0.0476190476190476 1.41784573254222 0.414373786372919 0.672584052183726 GO:0031492 nucleosomal DNA binding 2/626 42/18639 0.0476190476190476 1.41784573254222 0.414373786372919 0.672584052183726 GO:0043175 RNA polymerase core enzyme binding 2/626 42/18639 0.0476190476190476 1.41784573254222 0.414373786372919 0.672584052183726 GO:0008170 N-methyltransferase activity 4/626 98/18639 0.0408163265306122 1.21529634217904 0.418998855107379 0.672584052183726 GO:0042626 ATPase-coupled transmembrane transporter activity 4/626 98/18639 0.0408163265306122 1.21529634217904 0.418998855107379 0.672584052183726 GO:0016278 lysine N-methyltransferase activity 3/626 70/18639 0.0428571428571429 1.276061159288 0.419163502258272 0.672584052183726 GO:0004386 helicase activity 6/626 155/18639 0.0387096774193548 1.15257136967948 0.420822311469907 0.672584052183726 GO:0000062 fatty-acyl-CoA binding 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0005159 insulin-like growth factor receptor binding 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0005521 lamin binding 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0016722 oxidoreductase activity, acting on metal ions 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0022858 alanine transmembrane transporter activity 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0043023 ribosomal large subunit binding 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/626 16/18639 0.0625 1.86092252396166 0.42121425490294 0.672584052183726 GO:0061135 endopeptidase regulator activity 7/626 184/18639 0.0380434782608696 1.13273544936797 0.423138737392284 0.674426215586852 GO:0042826 histone deacetylase binding 5/626 127/18639 0.0393700787401575 1.17223466076325 0.423881796552904 0.674426215586852 GO:0008375 acetylglucosaminyltransferase activity 2/626 43/18639 0.0465116279069767 1.38487257597147 0.426064219472536 0.675486155782971 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/626 43/18639 0.0465116279069767 1.38487257597147 0.426064219472536 0.675486155782971 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 5/626 128/18639 0.0390625 1.16307657747604 0.430514815656388 0.676959924826919 GO:0001046 core promoter sequence-specific DNA binding 2/626 44/18639 0.0454545454545455 1.35339819924484 0.437631376692281 0.676959924826919 GO:0016790 thiolester hydrolase activity 2/626 44/18639 0.0454545454545455 1.35339819924484 0.437631376692281 0.676959924826919 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/626 44/18639 0.0454545454545455 1.35339819924484 0.437631376692281 0.676959924826919 GO:0043014 alpha-tubulin binding 2/626 44/18639 0.0454545454545455 1.35339819924484 0.437631376692281 0.676959924826919 GO:0008234 cysteine-type peptidase activity 7/626 187/18639 0.0374331550802139 1.11456322290752 0.439611635083888 0.676959924826919 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0004659 prenyltransferase activity 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0030169 low-density lipoprotein particle binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0031489 myosin V binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0032183 SUMO binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0036041 long-chain fatty acid binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0038191 neuropilin binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0046965 nuclear retinoid X receptor binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0070403 NAD+ binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:1901567 fatty acid derivative binding 1/626 17/18639 0.0588235294117647 1.75145649314039 0.440669760268926 0.676959924826919 GO:0046943 carboxylic acid transmembrane transporter activity 7/626 188/18639 0.0372340425531915 1.1086346951261 0.445087353376672 0.682569418001059 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/626 73/18639 0.0410958904109589 1.22362028972822 0.445957671228827 0.682729012138978 GO:0005342 organic acid transmembrane transporter activity 7/626 189/18639 0.037037037037037 1.10276890308839 0.450553832639603 0.683659378474983 GO:0004722 protein serine/threonine phosphatase activity 4/626 103/18639 0.0388349514563107 1.1563013741121 0.456518961688208 0.683659378474983 GO:0005253 monoatomic anion channel activity 4/626 103/18639 0.0388349514563107 1.1563013741121 0.456518961688208 0.683659378474983 GO:0004866 endopeptidase inhibitor activity 6/626 161/18639 0.0372670807453416 1.10961839938087 0.456603451692798 0.683659378474983 GO:0005178 integrin binding 6/626 161/18639 0.0372670807453416 1.10961839938087 0.456603451692798 0.683659378474983 GO:0001217 DNA-binding transcription repressor activity 10/626 278/18639 0.0359712230215827 1.07103454616498 0.457921121340295 0.683659378474983 GO:0140104 molecular carrier activity 9/626 249/18639 0.036144578313253 1.07619615843566 0.459120962624936 0.683659378474983 GO:0000400 four-way junction DNA binding 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0000900 mRNA regulatory element binding translation repressor activity 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0003746 translation elongation factor activity 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0008308 voltage-gated monoatomic anion channel activity 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0008409 5'-3' exonuclease activity 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0017128 phospholipid scramblase activity 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0070628 proteasome binding 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0098641 cadherin binding involved in cell-cell adhesion 1/626 18/18639 0.0555555555555556 1.65415335463259 0.45947229115023 0.683659378474983 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/626 46/18639 0.0434782608695652 1.29455479927768 0.460376685841739 0.683659378474983 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/626 46/18639 0.0434782608695652 1.29455479927768 0.460376685841739 0.683659378474983 GO:0019003 GDP binding 3/626 75/18639 0.04 1.19099041533546 0.463544842641925 0.687218726778627 GO:0022804 active transmembrane transporter activity 16/626 457/18639 0.0350109409190372 1.04244237666124 0.468575330271973 0.690877536708862 GO:0001784 phosphotyrosine residue binding 2/626 47/18639 0.0425531914893617 1.26701108014411 0.471546392455599 0.690877536708862 GO:0005504 fatty acid binding 2/626 47/18639 0.0425531914893617 1.26701108014411 0.471546392455599 0.690877536708862 GO:0043495 protein-membrane adaptor activity 2/626 47/18639 0.0425531914893617 1.26701108014411 0.471546392455599 0.690877536708862 GO:0061733 protein-lysine-acetyltransferase activity 2/626 47/18639 0.0425531914893617 1.26701108014411 0.471546392455599 0.690877536708862 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0005520 insulin-like growth factor binding 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0008574 plus-end-directed microtubule motor activity 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0015245 fatty acid transmembrane transporter activity 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0022821 solute:potassium antiporter activity 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0042577 lipid phosphatase activity 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0043395 heparan sulfate proteoglycan binding 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0050145 nucleoside monophosphate kinase activity 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0097001 ceramide binding 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0120227 acyl-CoA binding 1/626 19/18639 0.0526315789473684 1.56709265175719 0.47764372908267 0.690877536708862 GO:0015103 inorganic anion transmembrane transporter activity 6/626 165/18639 0.0363636363636364 1.08271855939588 0.480168150929335 0.693313207349733 GO:0003724 RNA helicase activity 3/626 77/18639 0.038961038961039 1.16005559935272 0.480883908128098 0.693313207349733 GO:0061134 peptidase regulator activity 8/626 226/18639 0.0353982300884956 1.05397381888094 0.490519066768749 0.706062178499121 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/626 167/18639 0.0359281437125748 1.06975187006179 0.491836644720659 0.706816855558238 GO:0000339 RNA cap binding 1/626 20/18639 0.05 1.48873801916933 0.495205223475486 0.708230905484203 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/626 20/18639 0.05 1.48873801916933 0.495205223475486 0.708230905484203 GO:0043024 ribosomal small subunit binding 1/626 20/18639 0.05 1.48873801916933 0.495205223475486 0.708230905484203 GO:0008186 ATP-dependent activity, acting on RNA 3/626 79/18639 0.0379746835443038 1.13068710316658 0.497953931050189 0.70988312410515 GO:0015370 solute:sodium symporter activity 3/626 79/18639 0.0379746835443038 1.13068710316658 0.497953931050189 0.70988312410515 GO:0004620 phospholipase activity 4/626 109/18639 0.036697247706422 1.0926517571885 0.500405759013864 0.712238867861586 GO:0070851 growth factor receptor binding 5/626 139/18639 0.0359712230215827 1.07103454616498 0.502101452725349 0.713512590714969 GO:0030414 peptidase inhibitor activity 6/626 169/18639 0.0355029585798817 1.05709208461728 0.503418130250939 0.714219113312528 GO:0032813 tumor necrosis factor receptor superfamily binding 2/626 50/18639 0.04 1.19099041533546 0.504201820733536 0.714219113312528 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0005123 death receptor binding 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0009975 cyclase activity 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0010314 phosphatidylinositol-5-phosphate binding 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0015125 bile acid transmembrane transporter activity 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0015174 basic amino acid transmembrane transporter activity 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0036122 BMP binding 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0072542 protein phosphatase activator activity 1/626 21/18639 0.0476190476190476 1.41784573254222 0.512177216069307 0.715281974165757 GO:0015101 organic cation transmembrane transporter activity 3/626 81/18639 0.037037037037037 1.10276890308839 0.514736287860031 0.716688354716324 GO:0016830 carbon-carbon lyase activity 2/626 51/18639 0.0392156862745098 1.16763766209359 0.514792982063353 0.716688354716324 GO:0005200 structural constituent of cytoskeleton 4/626 112/18639 0.0357142857142857 1.06338429940666 0.521767620406109 0.724135435797263 GO:0043022 ribosome binding 4/626 112/18639 0.0357142857142857 1.06338429940666 0.521767620406109 0.724135435797263 GO:0030159 signaling receptor complex adaptor activity 2/626 52/18639 0.0384615384615385 1.14518309166871 0.525233309940016 0.727811631658716 GO:0008093 cytoskeletal anchor activity 1/626 22/18639 0.0454545454545455 1.35339819924484 0.52857946457831 0.729046908574728 GO:0016881 acid-amino acid ligase activity 1/626 22/18639 0.0454545454545455 1.35339819924484 0.52857946457831 0.729046908574728 GO:0061133 endopeptidase activator activity 1/626 22/18639 0.0454545454545455 1.35339819924484 0.52857946457831 0.729046908574728 GO:0001540 amyloid-beta binding 3/626 83/18639 0.036144578313253 1.07619615843566 0.531214555343972 0.731284297100506 GO:0004864 protein phosphatase inhibitor activity 2/626 53/18639 0.0377358490566038 1.12357586352402 0.535520976421778 0.731284297100506 GO:0005544 calcium-dependent phospholipid binding 2/626 53/18639 0.0377358490566038 1.12357586352402 0.535520976421778 0.731284297100506 GO:0017046 peptide hormone binding 2/626 53/18639 0.0377358490566038 1.12357586352402 0.535520976421778 0.731284297100506 GO:0034212 protein N-acetyltransferase activity 2/626 53/18639 0.0377358490566038 1.12357586352402 0.535520976421778 0.731284297100506 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/626 53/18639 0.0377358490566038 1.12357586352402 0.535520976421778 0.731284297100506 GO:0016757 glycosyltransferase activity 9/626 267/18639 0.0337078651685393 1.00364360842876 0.543131187290043 0.731284297100506 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0005283 amino acid:sodium symporter activity 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0016849 phosphorus-oxygen lyase activity 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0031681 G-protein beta-subunit binding 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0042171 lysophosphatidic acid acyltransferase activity 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0070577 lysine-acetylated histone binding 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0071617 lysophospholipid acyltransferase activity 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0099186 structural constituent of postsynapse 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/626 23/18639 0.0434782608695652 1.29455479927768 0.54443106554377 0.731284297100506 GO:0050661 NADP binding 2/626 54/18639 0.037037037037037 1.10276890308839 0.545654445848007 0.731284297100506 GO:0051287 NAD binding 2/626 54/18639 0.037037037037037 1.10276890308839 0.545654445848007 0.731284297100506 GO:0015293 symporter activity 5/626 146/18639 0.0342465753424658 1.01968357477351 0.545795799743925 0.731284297100506 GO:0015294 solute:monoatomic cation symporter activity 4/626 116/18639 0.0344827586206897 1.02671587528919 0.549553908650399 0.735214012924183 GO:0050660 flavin adenine dinucleotide binding 3/626 86/18639 0.0348837209302326 1.0386544319786 0.555330967801398 0.741066381121689 GO:0098632 cell-cell adhesion mediator activity 2/626 55/18639 0.0363636363636364 1.08271855939588 0.5556324573258 0.741066381121689 GO:0003924 GTPase activity 11/626 331/18639 0.0332326283987915 0.989493547484146 0.557403135457268 0.741066381121689 GO:0015295 solute:proton symporter activity 1/626 24/18639 0.0416666666666667 1.24061501597444 0.559750476425249 0.741066381121689 GO:0035035 histone acetyltransferase binding 1/626 24/18639 0.0416666666666667 1.24061501597444 0.559750476425249 0.741066381121689 GO:0070300 phosphatidic acid binding 1/626 24/18639 0.0416666666666667 1.24061501597444 0.559750476425249 0.741066381121689 GO:0140612 DNA damage sensor activity 1/626 24/18639 0.0416666666666667 1.24061501597444 0.559750476425249 0.741066381121689 GO:0019212 phosphatase inhibitor activity 2/626 56/18639 0.0357142857142857 1.06338429940666 0.565454008060167 0.743730680267792 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/626 56/18639 0.0357142857142857 1.06338429940666 0.565454008060167 0.743730680267792 GO:0170055 lipid transmembrane transporter activity 2/626 56/18639 0.0357142857142857 1.06338429940666 0.565454008060167 0.743730680267792 GO:0001848 complement binding 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0004709 MAP kinase kinase kinase activity 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0005251 delayed rectifier potassium channel activity 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0015662 P-type ion transporter activity 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0017025 TBP-class protein binding 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0017056 structural constituent of nuclear pore 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0042974 nuclear retinoic acid receptor binding 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0047617 fatty acyl-CoA hydrolase activity 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0120020 cholesterol transfer activity 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0140358 P-type transmembrane transporter activity 1/626 25/18639 0.04 1.19099041533546 0.574555536954811 0.743730680267792 GO:0004601 peroxidase activity 2/626 57/18639 0.0350877192982456 1.04472843450479 0.575118337491031 0.743730680267792 GO:0016504 peptidase activator activity 2/626 57/18639 0.0350877192982456 1.04472843450479 0.575118337491031 0.743730680267792 GO:0140097 catalytic activity, acting on DNA 11/626 336/18639 0.0327380952380952 0.974768941122775 0.577524337090941 0.745759687460911 GO:0015108 chloride transmembrane transporter activity 4/626 121/18639 0.0330578512396694 0.984289599450796 0.583056178709466 0.750611401134388 GO:0016741 transferase activity, transferring one-carbon groups 7/626 215/18639 0.0325581395348837 0.969410803180028 0.586673622178392 0.750611401134388 GO:0061775 cohesin loader activity 5/626 153/18639 0.0326797385620915 0.973031385077993 0.587587017176562 0.750611401134388 GO:0005112 Notch binding 1/626 26/18639 0.0384615384615385 1.14518309166871 0.58886348977883 0.750611401134388 GO:0015145 monosaccharide transmembrane transporter activity 1/626 26/18639 0.0384615384615385 1.14518309166871 0.58886348977883 0.750611401134388 GO:0016289 acyl-CoA hydrolase activity 1/626 26/18639 0.0384615384615385 1.14518309166871 0.58886348977883 0.750611401134388 GO:0043548 phosphatidylinositol 3-kinase binding 1/626 26/18639 0.0384615384615385 1.14518309166871 0.58886348977883 0.750611401134388 GO:0070006 metalloaminopeptidase activity 1/626 26/18639 0.0384615384615385 1.14518309166871 0.58886348977883 0.750611401134388 GO:0070412 R-SMAD binding 1/626 26/18639 0.0384615384615385 1.14518309166871 0.58886348977883 0.750611401134388 GO:0072341 modified amino acid binding 3/626 91/18639 0.032967032967033 0.981585507144613 0.593828850845177 0.753889330064012 GO:0001786 phosphatidylserine binding 2/626 59/18639 0.0338983050847458 1.00931391130124 0.593973411565585 0.753889330064012 GO:0070888 E-box binding 2/626 59/18639 0.0338983050847458 1.00931391130124 0.593973411565585 0.753889330064012 GO:0001671 ATPase activator activity 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0004364 glutathione transferase activity 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0005044 scavenger receptor activity 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0005104 fibroblast growth factor receptor binding 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0005385 zinc ion transmembrane transporter activity 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0035255 ionotropic glutamate receptor binding 1/626 27/18639 0.037037037037037 1.10276890308839 0.6026910004111 0.756927984873909 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/626 60/18639 0.0333333333333333 0.992492012779553 0.603163714097054 0.756927984873909 GO:0140375 immune receptor activity 5/626 156/18639 0.032051282051282 0.954319243057262 0.60484259324379 0.757967300394117 GO:0051219 phosphoprotein binding 3/626 93/18639 0.032258064516129 0.960476141399567 0.608609302088797 0.761616415956627 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/626 61/18639 0.0327868852459016 0.976221651914314 0.612195884478185 0.763501952490649 GO:0016866 intramolecular transferase activity 1/626 28/18639 0.0357142857142857 1.06338429940666 0.616054176520205 0.763501952490649 GO:0019789 SUMO transferase activity 1/626 28/18639 0.0357142857142857 1.06338429940666 0.616054176520205 0.763501952490649 GO:0046625 sphingolipid binding 1/626 28/18639 0.0357142857142857 1.06338429940666 0.616054176520205 0.763501952490649 GO:0051119 sugar transmembrane transporter activity 1/626 28/18639 0.0357142857142857 1.06338429940666 0.616054176520205 0.763501952490649 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/626 28/18639 0.0357142857142857 1.06338429940666 0.616054176520205 0.763501952490649 GO:0140658 ATP-dependent chromatin remodeler activity 5/626 158/18639 0.0316455696202532 0.942239252638816 0.616114370191668 0.763501952490649 GO:0015179 L-amino acid transmembrane transporter activity 2/626 62/18639 0.032258064516129 0.960476141399567 0.621070161228816 0.768574324520659 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/626 29/18639 0.0344827586206897 1.02671587528919 0.62896858657331 0.773986438605223 GO:0005416 amino acid:monoatomic cation symporter activity 1/626 29/18639 0.0344827586206897 1.02671587528919 0.62896858657331 0.773986438605223 GO:0051861 glycolipid binding 1/626 29/18639 0.0344827586206897 1.02671587528919 0.62896858657331 0.773986438605223 GO:0097472 cyclin-dependent protein kinase activity 1/626 29/18639 0.0344827586206897 1.02671587528919 0.62896858657331 0.773986438605223 GO:0005507 copper ion binding 2/626 63/18639 0.0317460317460317 0.945230488361479 0.629786944993026 0.773986438605223 GO:0030594 neurotransmitter receptor activity 3/626 97/18639 0.0309278350515464 0.920868877836698 0.63707749358651 0.77759361438277 GO:0008083 growth factor activity 5/626 162/18639 0.0308641975308642 0.918974085906993 0.638081586808247 0.77759361438277 GO:0016298 lipase activity 4/626 130/18639 0.0307692307692308 0.916146473334972 0.639563980907162 0.77759361438277 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/626 130/18639 0.0307692307692308 0.916146473334972 0.639563980907162 0.77759361438277 GO:0001968 fibronectin binding 1/626 30/18639 0.0333333333333333 0.992492012779553 0.641449277857841 0.77759361438277 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/626 30/18639 0.0333333333333333 0.992492012779553 0.641449277857841 0.77759361438277 GO:0031210 phosphatidylcholine binding 1/626 30/18639 0.0333333333333333 0.992492012779553 0.641449277857841 0.77759361438277 GO:0031624 ubiquitin conjugating enzyme binding 1/626 30/18639 0.0333333333333333 0.992492012779553 0.641449277857841 0.77759361438277 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/626 30/18639 0.0333333333333333 0.992492012779553 0.641449277857841 0.77759361438277 GO:0098918 structural constituent of synapse 1/626 30/18639 0.0333333333333333 0.992492012779553 0.641449277857841 0.77759361438277 GO:0015081 sodium ion transmembrane transporter activity 5/626 164/18639 0.0304878048780488 0.907767084859347 0.648769677214048 0.785399160866463 GO:0005179 hormone activity 4/626 132/18639 0.0303030303030303 0.90226546616323 0.651419988858571 0.785800428294809 GO:0016758 hexosyltransferase activity 6/626 197/18639 0.0304568527918782 0.906845493910251 0.65276066459799 0.785800428294809 GO:0005164 tumor necrosis factor receptor binding 1/626 31/18639 0.032258064516129 0.960476141399567 0.653510793901744 0.785800428294809 GO:0008327 methyl-CpG binding 1/626 31/18639 0.032258064516129 0.960476141399567 0.653510793901744 0.785800428294809 GO:0016411 acylglycerol O-acyltransferase activity 1/626 31/18639 0.032258064516129 0.960476141399567 0.653510793901744 0.785800428294809 GO:0015399 primary active transmembrane transporter activity 5/626 166/18639 0.0301204819277108 0.896830132029716 0.659256664540112 0.79164108909062 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/626 67/18639 0.0298507462686567 0.888798817414525 0.663092229962487 0.792331507298595 GO:0031369 translation initiation factor binding 1/626 32/18639 0.03125 0.930461261980831 0.665167191312401 0.792331507298595 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/626 32/18639 0.03125 0.930461261980831 0.665167191312401 0.792331507298595 GO:0042910 xenobiotic transmembrane transporter activity 1/626 32/18639 0.03125 0.930461261980831 0.665167191312401 0.792331507298595 GO:0071813 lipoprotein particle binding 1/626 32/18639 0.03125 0.930461261980831 0.665167191312401 0.792331507298595 GO:0071814 protein-lipid complex binding 1/626 32/18639 0.03125 0.930461261980831 0.665167191312401 0.792331507298595 GO:0015297 antiporter activity 4/626 135/18639 0.0296296296296296 0.882215122470714 0.668711065207494 0.795489397997165 GO:0005548 phospholipid transporter activity 2/626 68/18639 0.0294117647058824 0.875728246570194 0.671032484852244 0.796125091881957 GO:0030145 manganese ion binding 2/626 68/18639 0.0294117647058824 0.875728246570194 0.671032484852244 0.796125091881957 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/626 33/18639 0.0303030303030303 0.90226546616323 0.676432056053543 0.798981557415675 GO:0019956 chemokine binding 1/626 33/18639 0.0303030303030303 0.90226546616323 0.676432056053543 0.798981557415675 GO:0071889 14-3-3 protein binding 1/626 33/18639 0.0303030303030303 0.90226546616323 0.676432056053543 0.798981557415675 GO:0002039 p53 binding 2/626 69/18639 0.0289855072463768 0.863036532851785 0.678820470217358 0.798981557415675 GO:0008080 N-acetyltransferase activity 2/626 69/18639 0.0289855072463768 0.863036532851785 0.678820470217358 0.798981557415675 GO:0098960 postsynaptic neurotransmitter receptor activity 2/626 69/18639 0.0289855072463768 0.863036532851785 0.678820470217358 0.798981557415675 GO:0008168 methyltransferase activity 6/626 204/18639 0.0294117647058824 0.875728246570194 0.685481264130514 0.803675591323365 GO:0097110 scaffold protein binding 2/626 70/18639 0.0285714285714286 0.850707439525331 0.686457439863213 0.803675591323365 GO:0008175 tRNA methyltransferase activity 1/626 34/18639 0.0294117647058824 0.875728246570194 0.687318519178905 0.803675591323365 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/626 34/18639 0.0294117647058824 0.875728246570194 0.687318519178905 0.803675591323365 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/626 34/18639 0.0294117647058824 0.875728246570194 0.687318519178905 0.803675591323365 GO:0140767 enzyme-substrate adaptor activity 4/626 139/18639 0.0287769784172662 0.856827636931988 0.690836143532478 0.806730018201098 GO:0016229 steroid dehydrogenase activity 1/626 35/18639 0.0285714285714286 0.850707439525331 0.697839272040717 0.813841349984658 GO:0020037 heme binding 4/626 142/18639 0.028169014084507 0.838725644602439 0.70672876100625 0.823131145171985 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/626 36/18639 0.0277777777777778 0.827076677316294 0.70800658099054 0.823542902953748 GO:0004175 endopeptidase activity 12/626 405/18639 0.0296296296296296 0.882215122470714 0.711663874140886 0.825884312312041 GO:0008094 ATP-dependent activity, acting on DNA 6/626 210/18639 0.0285714285714286 0.850707439525331 0.711873346639335 0.825884312312041 GO:0003684 damaged DNA binding 2/626 74/18639 0.027027027027027 0.804723253605043 0.715523151028901 0.829039177590053 GO:0043394 proteoglycan binding 1/626 37/18639 0.027027027027027 0.804723253605043 0.717832301589364 0.83063452041055 GO:0004222 metalloendopeptidase activity 3/626 110/18639 0.0272727272727273 0.812038919546907 0.719366593498581 0.831330265638438 GO:0008194 UDP-glycosyltransferase activity 4/626 145/18639 0.0275862068965517 0.821372700231354 0.722020395948615 0.833316285997689 GO:0005109 frizzled binding 1/626 38/18639 0.0263157894736842 0.783546325878594 0.727327892343318 0.835366009538769 GO:0042887 amide transmembrane transporter activity 1/626 38/18639 0.0263157894736842 0.783546325878594 0.727327892343318 0.835366009538769 GO:0033218 amide binding 7/626 247/18639 0.0283400809716599 0.843819120176948 0.727540416444058 0.835366009538769 GO:0030246 carbohydrate binding 8/626 280/18639 0.0285714285714286 0.850707439525331 0.727546603144876 0.835366009538769 GO:0000217 DNA secondary structure binding 1/626 39/18639 0.0256410256410256 0.76345539444581 0.736504427980815 0.843477436157977 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/626 39/18639 0.0256410256410256 0.76345539444581 0.736504427980815 0.843477436157977 GO:0008509 monoatomic anion transmembrane transporter activity 4/626 149/18639 0.0268456375838926 0.79932242639964 0.74147951613954 0.846599657349033 GO:0004857 enzyme inhibitor activity 12/626 416/18639 0.0288461538461538 0.858887318751536 0.744710034843451 0.846599657349033 GO:0004177 aminopeptidase activity 1/626 40/18639 0.025 0.744369009584665 0.745372612286407 0.846599657349033 GO:0030331 nuclear estrogen receptor binding 1/626 40/18639 0.025 0.744369009584665 0.745372612286407 0.846599657349033 GO:0033293 monocarboxylic acid binding 2/626 79/18639 0.0253164556962025 0.753791402111053 0.748639251297998 0.846599657349033 GO:0000510 H3-H4 histone complex chaperone activity 4/626 151/18639 0.0264900662251656 0.788735374394346 0.75081409493649 0.846599657349033 GO:0140584 chromatin extrusion motor activity 4/626 151/18639 0.0264900662251656 0.788735374394346 0.75081409493649 0.846599657349033 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/626 151/18639 0.0264900662251656 0.788735374394346 0.75081409493649 0.846599657349033 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/626 151/18639 0.0264900662251656 0.788735374394346 0.75081409493649 0.846599657349033 GO:0001530 lipopolysaccharide binding 1/626 41/18639 0.024390243902439 0.726213667887478 0.753942790506135 0.846599657349033 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/626 41/18639 0.024390243902439 0.726213667887478 0.753942790506135 0.846599657349033 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/626 41/18639 0.024390243902439 0.726213667887478 0.753942790506135 0.846599657349033 GO:0000049 tRNA binding 2/626 80/18639 0.025 0.744369009584665 0.754850971987604 0.846599657349033 GO:0048306 calcium-dependent protein binding 2/626 80/18639 0.025 0.744369009584665 0.754850971987604 0.846599657349033 GO:0015616 DNA translocase activity 4/626 152/18639 0.0263157894736842 0.783546325878594 0.755383532651494 0.846599657349033 GO:0046906 tetrapyrrole binding 4/626 152/18639 0.0263157894736842 0.783546325878594 0.755383532651494 0.846599657349033 GO:0140674 ATP-dependent histone chaperone activity 4/626 152/18639 0.0263157894736842 0.783546325878594 0.755383532651494 0.846599657349033 GO:0019894 kinesin binding 1/626 42/18639 0.0238095238095238 0.708922866271109 0.762224961338652 0.853194020794898 GO:0042605 peptide antigen binding 1/626 45/18639 0.0222222222222222 0.661661341853035 0.78543845899712 0.87587692987038 GO:0046915 transition metal ion transmembrane transporter activity 1/626 45/18639 0.0222222222222222 0.661661341853035 0.78543845899712 0.87587692987038 GO:0051539 4 iron, 4 sulfur cluster binding 1/626 45/18639 0.0222222222222222 0.661661341853035 0.78543845899712 0.87587692987038 GO:0016209 antioxidant activity 2/626 86/18639 0.0232558139534884 0.692436287985734 0.789398324091816 0.877824714103233 GO:0003689 DNA clamp loader activity 4/626 160/18639 0.025 0.744369009584665 0.789634926365769 0.877824714103233 GO:0019001 guanyl nucleotide binding 11/626 400/18639 0.0275 0.818805910543131 0.791125976907852 0.877824714103233 GO:0032561 guanyl ribonucleotide binding 11/626 400/18639 0.0275 0.818805910543131 0.791125976907852 0.877824714103233 GO:0030291 protein serine/threonine kinase inhibitor activity 1/626 46/18639 0.0217391304347826 0.647277399638839 0.792662053956128 0.878435186660336 GO:0008081 phosphoric diester hydrolase activity 2/626 87/18639 0.0229885057471264 0.684477250192795 0.794720556590674 0.87962238002769 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/626 88/18639 0.0227272727272727 0.676699099622422 0.799923579663996 0.884282766104988 GO:0008514 organic anion transmembrane transporter activity 7/626 269/18639 0.0260223048327138 0.774807891017495 0.802971820928597 0.885934082127795 GO:0004519 endonuclease activity 3/626 127/18639 0.0236220472440945 0.703340796457951 0.804160869700632 0.885934082127795 GO:0140713 histone chaperone activity 4/626 164/18639 0.024390243902439 0.726213667887478 0.805266521974402 0.885934082127795 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/626 48/18639 0.0208333333333333 0.62030750798722 0.806388934462 0.885934082127795 GO:0038187 pattern recognition receptor activity 1/626 48/18639 0.0208333333333333 0.62030750798722 0.806388934462 0.885934082127795 GO:0016763 pentosyltransferase activity 1/626 49/18639 0.0204081632653061 0.607648171089522 0.812908246334776 0.889804972339417 GO:0035254 glutamate receptor binding 1/626 49/18639 0.0204081632653061 0.607648171089522 0.812908246334776 0.889804972339417 GO:0060590 ATPase regulator activity 1/626 49/18639 0.0204081632653061 0.607648171089522 0.812908246334776 0.889804972339417 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/626 91/18639 0.021978021978022 0.654390338096408 0.814837280934126 0.890822107131664 GO:0052689 carboxylic ester hydrolase activity 2/626 92/18639 0.0217391304347826 0.647277399638839 0.819583351311183 0.893737099074623 GO:0005525 GTP binding 10/626 378/18639 0.0264550264550265 0.787692073634566 0.82038214920929 0.893737099074623 GO:0005126 cytokine receptor binding 7/626 275/18639 0.0254545454545455 0.757902991577113 0.820512847410821 0.893737099074623 GO:0051213 dioxygenase activity 2/626 93/18639 0.021505376344086 0.640317427599711 0.824220143601785 0.896679057325018 GO:0005272 sodium channel activity 1/626 51/18639 0.0196078431372549 0.583818831046796 0.825296685377619 0.896755300818851 GO:0016410 N-acyltransferase activity 2/626 94/18639 0.0212765957446809 0.633505540072055 0.828749630215089 0.899410378223684 GO:0046873 metal ion transmembrane transporter activity 12/626 450/18639 0.0266666666666667 0.793993610223642 0.830366885005703 0.900069214768956 GO:0051087 protein-folding chaperone binding 3/626 134/18639 0.0223880597014925 0.666599113060894 0.832249483614564 0.900919700399449 GO:0004867 serine-type endopeptidase inhibitor activity 2/626 95/18639 0.0210526315789474 0.626837060702875 0.83317377455572 0.900919700399449 GO:0005246 calcium channel regulator activity 1/626 53/18639 0.0188679245283019 0.561787931762011 0.836866036831216 0.903815319777713 GO:0003823 antigen binding 4/626 174/18639 0.0229885057471264 0.684477250192795 0.840236264038498 0.906356551160172 GO:0003925 G protein activity 1/626 54/18639 0.0185185185185185 0.551384451544196 0.842360595151654 0.906453249130584 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/626 54/18639 0.0185185185185185 0.551384451544196 0.842360595151654 0.906453249130584 GO:0140313 molecular sequestering activity 1/626 55/18639 0.0181818181818182 0.541359279697938 0.847670375481762 0.911066712369421 GO:0030170 pyridoxal phosphate binding 1/626 56/18639 0.0178571428571429 0.531692149703332 0.852801582162155 0.915477361092145 GO:0070279 vitamin B6 binding 1/626 57/18639 0.0175438596491228 0.522364217252396 0.857760211531282 0.919692356768198 GO:0015171 amino acid transmembrane transporter activity 2/626 102/18639 0.0196078431372549 0.583818831046796 0.861355541395956 0.922437244451679 GO:0008237 metallopeptidase activity 4/626 184/18639 0.0217391304347826 0.647277399638839 0.869783268455459 0.930344408395935 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/626 60/18639 0.0166666666666667 0.496246006389776 0.871657623714712 0.931231346198811 GO:0015276 ligand-gated monoatomic ion channel activity 4/626 186/18639 0.021505376344086 0.640317427599711 0.875094261536003 0.932323395202461 GO:0004497 monooxygenase activity 2/626 106/18639 0.0188679245283019 0.561787931762011 0.875434987817425 0.932323395202461 GO:0046982 protein heterodimerization activity 9/626 369/18639 0.024390243902439 0.726213667887478 0.875818947008373 0.932323395202461 GO:0022834 ligand-gated channel activity 4/626 188/18639 0.0212765957446809 0.633505540072055 0.880217179967304 0.93477176084728 GO:0140597 protein carrier chaperone 4/626 188/18639 0.0212765957446809 0.633505540072055 0.880217179967304 0.93477176084728 GO:0019842 vitamin binding 3/626 150/18639 0.02 0.595495207667732 0.883721572558128 0.936767478394091 GO:1901682 sulfur compound transmembrane transporter activity 1/626 63/18639 0.0158730158730159 0.472615244180739 0.884199157496555 0.936767478394091 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/626 229/18639 0.0218340611353712 0.65010393850189 0.886917910632535 0.938531898305925 GO:0003774 cytoskeletal motor activity 3/626 153/18639 0.0196078431372549 0.583818831046796 0.891637188188524 0.941538584659421 GO:0160215 deacylase activity 1/626 65/18639 0.0153846153846154 0.458073236667486 0.891872688498935 0.941538584659421 GO:0008235 metalloexopeptidase activity 1/626 66/18639 0.0151515151515152 0.451132733081615 0.895516906061101 0.94426693881709 GO:0008173 RNA methyltransferase activity 1/626 67/18639 0.0149253731343284 0.444399408707262 0.899038492062595 0.946859688448903 GO:0003777 microtubule motor activity 1/626 68/18639 0.0147058823529412 0.437864123285097 0.902441566797078 0.948202165113439 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/626 68/18639 0.0147058823529412 0.437864123285097 0.902441566797078 0.948202165113439 GO:0009055 electron transfer activity 2/626 116/18639 0.0172413793103448 0.513357937644596 0.905060586347858 0.949833901573547 GO:0140098 catalytic activity, acting on RNA 9/626 387/18639 0.0232558139534884 0.692436287985734 0.906347417903908 0.950065352179273 GO:0015079 potassium ion transmembrane transporter activity 3/626 160/18639 0.01875 0.558276757188498 0.908258952446857 0.950950325064805 GO:0051082 unfolded protein binding 2/626 121/18639 0.0165289256198347 0.492144799725398 0.917273385646614 0.95822591819964 GO:0004521 RNA endonuclease activity 1/626 73/18639 0.0136986301369863 0.407873429909405 0.917814061091787 0.95822591819964 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/626 122/18639 0.0163934426229508 0.488110825957157 0.91953195860926 0.95822591819964 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/626 122/18639 0.0163934426229508 0.488110825957157 0.91953195860926 0.95822591819964 GO:0048029 monosaccharide binding 1/626 74/18639 0.0135135135135135 0.402361626802521 0.920585169448813 0.95822591819964 GO:0044183 protein folding chaperone 1/626 75/18639 0.0133333333333333 0.396996805111821 0.923262987058564 0.959891857023548 GO:0051536 iron-sulfur cluster binding 1/626 76/18639 0.0131578947368421 0.391773162939297 0.92585064974448 0.961460290119268 GO:0051540 metal cluster binding 1/626 77/18639 0.012987012987013 0.386685199784241 0.928351188087418 0.962934701496961 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/626 130/18639 0.0153846153846154 0.458073236667486 0.935619774290801 0.967216738643874 GO:0001664 G protein-coupled receptor binding 6/626 297/18639 0.0202020202020202 0.601510310775487 0.936649774651914 0.967216738643874 GO:0005262 calcium channel activity 2/626 131/18639 0.0152671755725191 0.454576494402849 0.937402052390401 0.967216738643874 GO:0031072 heat shock protein binding 2/626 131/18639 0.0152671755725191 0.454576494402849 0.937402052390401 0.967216738643874 GO:0004252 serine-type endopeptidase activity 3/626 176/18639 0.0170454545454545 0.507524324716817 0.937907140503151 0.967216738643874 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/626 132/18639 0.0151515151515152 0.451132733081615 0.93913748831867 0.967365898372179 GO:0008135 translation factor activity, RNA binding 1/626 83/18639 0.0120481927710843 0.358732052811887 0.941682123299694 0.968654056735614 GO:0004860 protein kinase inhibitor activity 1/626 84/18639 0.0119047619047619 0.354461433135555 0.943649518795188 0.968654056735614 GO:0180051 translation factor activity 1/626 84/18639 0.0119047619047619 0.354461433135555 0.943649518795188 0.968654056735614 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/626 181/18639 0.0165745856353591 0.493504315746739 0.945177464432886 0.969106007836251 GO:0015078 proton transmembrane transporter activity 3/626 185/18639 0.0162162162162162 0.482833952163026 0.95041609214528 0.973357170231545 GO:0019210 kinase inhibitor activity 1/626 90/18639 0.0111111111111111 0.330830670926518 0.954137680087157 0.9760466968515 GO:0022836 gated channel activity 6/626 318/18639 0.0188679245283019 0.561787931762011 0.95843634356998 0.979227530959277 GO:0015085 calcium ion transmembrane transporter activity 2/626 147/18639 0.0136054421768707 0.405098780726348 0.960263249058266 0.979227530959277 GO:0008236 serine-type peptidase activity 3/626 194/18639 0.0154639175257732 0.460434438918349 0.960544177394398 0.979227530959277 GO:0017171 serine hydrolase activity 3/626 198/18639 0.0151515151515152 0.451132733081615 0.964392004387449 0.981680461706089 GO:0005249 voltage-gated potassium channel activity 1/626 98/18639 0.0102040816326531 0.303824085544761 0.96515385460666 0.981680461706089 GO:0005506 iron ion binding 2/626 154/18639 0.012987012987013 0.386685199784241 0.967520856484079 0.982965887260336 GO:0008238 exopeptidase activity 1/626 102/18639 0.00980392156862745 0.291909415523398 0.969627225398517 0.983983892744965 GO:0016874 ligase activity 2/626 167/18639 0.0119760479041916 0.356583956687264 0.97775771671332 0.991105944927836 GO:0005244 voltage-gated monoatomic ion channel activity 2/626 173/18639 0.0115606936416185 0.344216883044932 0.981354165083678 0.99249967349663 GO:0022832 voltage-gated channel activity 2/626 175/18639 0.0114285714285714 0.340282975810132 0.982422533472108 0.99249967349663 GO:0022853 active monoatomic ion transmembrane transporter activity 1/626 118/18639 0.00847457627118644 0.25232847782531 0.982474424269391 0.99249967349663 GO:0016853 isomerase activity 2/626 180/18639 0.0111111111111111 0.330830670926518 0.984840084545077 0.993547483780318 GO:0005267 potassium channel activity 1/626 124/18639 0.00806451612903226 0.240119035349892 0.985741835759597 0.993547483780318 GO:0099094 ligand-gated monoatomic cation channel activity 1/626 136/18639 0.00735294117647059 0.218932061642548 0.990564659268302 0.997061202483384 GO:0140101 catalytic activity, acting on a tRNA 1/626 139/18639 0.00719424460431655 0.214206909232997 0.991490332401523 0.997061202483384 GO:0022843 voltage-gated monoatomic cation channel activity 1/626 143/18639 0.00699300699300699 0.20821510757613 0.992585057915558 0.997061202483384 GO:0005216 monoatomic ion channel activity 7/626 448/18639 0.015625 0.465230630990415 0.993756834171866 0.997114120773798 GO:0005261 monoatomic cation channel activity 3/626 341/18639 0.00879765395894428 0.261948038563518 0.999329900553723 0.999849860731387 GO:0045182 translation regulator activity 3/626 356/18639 0.00842696629213483 0.25091090210719 0.999569085680492 0.999849860731387 GO:0030371 translation repressor activity 2/626 329/18639 0.0060790273556231 0.18100158287773 0.999849860731387 0.999849860731387