ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 82/1476 495/18639 0.165656565656566 2.09191919191919 1.05364996665081e-10 1.19589271214867e-07 GO:0004842 ubiquitin-protein transferase activity 73/1476 449/18639 0.162583518930958 2.0531126079635 2.62274702593002e-09 1.06578041800637e-06 GO:0051020 GTPase binding 57/1476 315/18639 0.180952380952381 2.28507549361208 2.95423785225076e-09 1.06578041800637e-06 GO:0019787 ubiquitin-like protein transferase activity 76/1476 479/18639 0.15866388308977 2.00361525535923 3.75605433658632e-09 1.06578041800637e-06 GO:0016755 aminoacyltransferase activity 77/1476 496/18639 0.155241935483871 1.96040273406766 7.94282961883122e-09 1.80302232347469e-06 GO:0031267 small GTPase binding 51/1476 283/18639 0.180212014134276 2.27572610531759 2.29112989214814e-08 4.33405404598023e-06 GO:0030695 GTPase regulator activity 74/1476 489/18639 0.151329243353783 1.91099306698588 4.59742119778624e-08 7.10385483074966e-06 GO:0060589 nucleoside-triphosphatase regulator activity 74/1476 490/18639 0.151020408163265 1.90709308113489 5.00712234766496e-08 7.10385483074966e-06 GO:0045296 cadherin binding 56/1476 334/18639 0.167664670658683 2.11727763984227 6.44222714127634e-08 7.49386728985922e-06 GO:0035173 histone kinase activity 59/1476 360/18639 0.163888888888889 2.06959688346883 6.602526246572e-08 7.49386728985922e-06 GO:0004674 protein serine/threonine kinase activity 67/1476 433/18639 0.15473441108545 1.95399369120712 8.47648950465673e-08 8.14259003413811e-06 GO:0141003 histone H2AX kinase activity 58/1476 354/18639 0.163841807909605 2.0690023425658 8.6089057629654e-08 8.14259003413811e-06 GO:0005096 GTPase activator activity 48/1476 271/18639 0.177121771217712 2.23670236702367 1.02110912043961e-07 8.91506808999197e-06 GO:0140996 histone H3 kinase activity 58/1476 357/18639 0.162464985994398 2.05161576825852 1.16039547472177e-07 9.4074918843515e-06 GO:0140857 histone H3T45 kinase activity 44/1476 246/18639 0.178861788617886 2.25867539163197 2.58901652463543e-07 1.95902250364081e-05 GO:0004679 AMP-activated protein kinase activity 44/1476 248/18639 0.17741935483871 2.2404602675059 3.27563793901532e-07 2.01132032239433e-05 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 43/1476 243/18639 0.176954732510288 2.23459299407809 4.78389549890885e-07 2.01132032239433e-05 GO:0004676 3-phosphoinositide-dependent protein kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0004711 ribosomal protein S6 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0035175 histone H3S10 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0035979 histone H2AXS139 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0044022 histone H3S28 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0044023 histone H4S1 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0044024 histone H2AS1 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0044025 histone H2BS14 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0072354 histone H3T3 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0072371 histone H2AS121 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0072518 Rho-dependent protein serine/threonine kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0140823 histone H2BS36 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0140855 histone H3S57 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0140995 histone H2A kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0140997 histone H4 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0140998 histone H2B kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:1990244 histone H2AT120 kinase activity 43/1476 245/18639 0.175510204081633 2.21635141861623 6.02510052523412e-07 2.01132032239433e-05 GO:0140030 modification-dependent protein binding 34/1476 173/18639 0.196531791907514 2.48181305512477 6.32348598401413e-07 2.05061616910172e-05 GO:0004677 DNA-dependent protein kinase activity 43/1476 246/18639 0.17479674796748 2.20734186000397 6.75294097856292e-07 2.12905222518581e-05 GO:0035402 histone H3T11 kinase activity 43/1476 247/18639 0.174089068825911 2.1984052532833 7.56225004695328e-07 2.25872468507684e-05 GO:0035403 histone H3T6 kinase activity 43/1476 247/18639 0.174089068825911 2.1984052532833 7.56225004695328e-07 2.25872468507684e-05 GO:0001221 transcription coregulator binding 26/1476 115/18639 0.226086956521739 2.85503711558855 8.25290397310468e-07 2.40180666909585e-05 GO:0106310 protein serine kinase activity 56/1476 361/18639 0.155124653739612 1.9589216944801 8.9017851447833e-07 2.52588153483226e-05 GO:0003713 transcription coactivator activity 43/1476 256/18639 0.16796875 2.12111756859756 2.01805921134128e-06 5.58657854846916e-05 GO:0061630 ubiquitin protein ligase activity 52/1476 353/18639 0.147308781869688 1.86022248324466 9.89595230180684e-06 0.000267426330060733 GO:0061659 ubiquitin-like protein ligase activity 54/1476 372/18639 0.145161290322581 1.8331038552321 1.03567544261899e-05 0.000273370145900593 GO:1990247 N6-methyladenosine-containing RNA reader activity 7/1476 12/18639 0.583333333333333 7.36636178861789 1.06860801476231e-05 0.000275354876840801 GO:0003714 transcription corepressor activity 35/1476 204/18639 0.17156862745098 2.16657699665232 1.09171537073445e-05 0.000275354876840801 GO:0003779 actin binding 61/1476 443/18639 0.137697516930023 1.73885096074437 1.52357225134431e-05 0.000375924892451259 GO:0140517 protein-RNA adaptor activity 9/1476 22/18639 0.409090909090909 5.1660199556541 2.30076114284275e-05 0.000555609339814152 GO:0019902 phosphatase binding 32/1476 190/18639 0.168421052631579 2.12682926829268 3.73214768420333e-05 0.000882497421160579 GO:0140297 DNA-binding transcription factor binding 64/1476 488/18639 0.131147540983607 1.65613754498201 4.37131253155062e-05 0.00101253871904285 GO:0042393 histone binding 37/1476 247/18639 0.149797570850202 1.89165103189493 0.000127547492872958 0.00285179145935113 GO:0035091 phosphatidylinositol binding 41/1476 284/18639 0.144366197183099 1.82306338028169 0.000130405832829859 0.00285179145935113 GO:1901981 phosphatidylinositol phosphate binding 30/1476 185/18639 0.162162162162162 2.04779169413316 0.000130654762895382 0.00285179145935113 GO:0070063 RNA polymerase binding 14/1476 59/18639 0.23728813559322 2.99648615130219 0.000160473007078842 0.00343654458555633 GO:0003725 double-stranded RNA binding 16/1476 75/18639 0.213333333333333 2.6939837398374 0.000213914926543515 0.00441442621139799 GO:0019003 GDP binding 16/1476 75/18639 0.213333333333333 2.6939837398374 0.000213914926543515 0.00441442621139799 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 47/1476 349/18639 0.134670487106017 1.70062548046684 0.000235514671213897 0.00477337771121024 GO:0031625 ubiquitin protein ligase binding 42/1476 302/18639 0.139072847682119 1.75621870457115 0.000248618133122416 0.00491821610752794 GO:0140034 methylation-dependent protein binding 16/1476 76/18639 0.210526315789474 2.65853658536585 0.000251327342939754 0.00491821610752794 GO:0044389 ubiquitin-like protein ligase binding 44/1476 322/18639 0.136645962732919 1.72557188304802 0.000266134751542226 0.00511971089831231 GO:0032266 phosphatidylinositol-3-phosphate binding 12/1476 48/18639 0.25 3.15701219512195 0.000276473783911427 0.00522996241232449 GO:0001222 transcription corepressor binding 12/1476 49/18639 0.244897959183673 3.09258337481334 0.000340062979415431 0.00632740133830351 GO:0019903 protein phosphatase binding 24/1476 144/18639 0.166666666666667 2.10467479674797 0.000391064787592809 0.00715900861157803 GO:0046332 SMAD binding 16/1476 79/18639 0.20253164556962 2.55757949984563 0.000399470128436789 0.00719680310755167 GO:0099122 RNA polymerase II C-terminal domain binding 5/1476 10/18639 0.5 6.3140243902439 0.000555714381300358 0.00985524723087354 GO:0035064 methylated histone binding 15/1476 74/18639 0.202702702702703 2.55973961766645 0.000594215596210745 0.0103759184876799 GO:0070717 poly-purine tract binding 9/1476 32/18639 0.28125 3.5516387195122 0.000628751924389098 0.0108126277906307 GO:0008143 poly(A) binding 8/1476 26/18639 0.307692307692308 3.88555347091933 0.00064956927564397 0.0110038974306852 GO:0019208 phosphatase regulator activity 20/1476 117/18639 0.170940170940171 2.1586408171774 0.000832412761317892 0.0138939482955266 GO:0016791 phosphatase activity 37/1476 273/18639 0.135531135531136 1.71149379076208 0.000918083242979459 0.0151018040692998 GO:0048185 activin binding 5/1476 11/18639 0.454545454545455 5.740022172949 0.000952465711669221 0.0154435511820652 GO:0052866 phosphatidylinositol phosphate phosphatase activity 9/1476 34/18639 0.264705882352941 3.34271879483501 0.00101804623047823 0.0162744010083491 GO:0016922 nuclear receptor binding 22/1476 137/18639 0.160583941605839 2.02786184796155 0.00111568205442602 0.017587487941299 GO:0015631 tubulin binding 48/1476 385/18639 0.124675324675325 1.57440608172315 0.00115304524007258 0.0179274842120874 GO:0005085 guanyl-nucleotide exchange factor activity 32/1476 230/18639 0.139130434782609 1.75694591728526 0.00127623204541158 0.0195746401559749 GO:0008429 phosphatidylethanolamine binding 6/1476 17/18639 0.352941176470588 4.45695839311334 0.00140815438122957 0.0213100696359408 GO:0106222 lncRNA binding 8/1476 29/18639 0.275862068965517 3.48359966358284 0.00144147914227944 0.0215273529800943 GO:0005095 GTPase inhibitor activity 5/1476 12/18639 0.416666666666667 5.26168699186992 0.00152669872745593 0.0225039357878245 GO:0048156 tau protein binding 10/1476 43/18639 0.232558139534884 2.936755530346 0.00160387492047934 0.0233384363428724 GO:0061980 regulatory RNA binding 12/1476 58/18639 0.206896551724138 2.61269974768713 0.00169420808841711 0.0243408377259927 GO:0042578 phosphoric ester hydrolase activity 45/1476 363/18639 0.12396694214876 1.56546059262246 0.00180968483801886 0.0256749036393926 GO:0005543 phospholipid binding 58/1476 497/18639 0.116700201207243 1.47369583353781 0.00186613015652403 0.0261488608352441 GO:0031593 polyubiquitin modification-dependent protein binding 12/1476 59/18639 0.203389830508475 2.56841670111616 0.00197630027162117 0.027354887905976 GO:0140033 acetylation-dependent protein binding 7/1476 24/18639 0.291666666666667 3.68318089430894 0.00200300033537577 0.0273904262729097 GO:0004535 poly(A)-specific ribonuclease activity 5/1476 13/18639 0.384615384615385 4.85694183864916 0.00232002628574527 0.0303497567104363 GO:0070123 transforming growth factor beta receptor activity, type III 5/1476 13/18639 0.384615384615385 4.85694183864916 0.00232002628574527 0.0303497567104363 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/1476 13/18639 0.384615384615385 4.85694183864916 0.00232002628574527 0.0303497567104363 GO:0019783 ubiquitin-like protein peptidase activity 20/1476 127/18639 0.15748031496063 1.98866909928942 0.00232636901657089 0.0303497567104363 GO:0031490 chromatin DNA binding 20/1476 128/18639 0.15625 1.97313262195122 0.00255683567264241 0.032977369186922 GO:0042974 nuclear retinoic acid receptor binding 7/1476 25/18639 0.28 3.53585365853659 0.00259412805838085 0.0330824196209243 GO:0019209 kinase activator activity 22/1476 148/18639 0.148648648648649 1.87714238628873 0.00304660370354261 0.0384210578168985 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 5/1476 14/18639 0.357142857142857 4.51001742160279 0.00337544431199229 0.0421003219133105 GO:0005516 calmodulin binding 28/1476 207/18639 0.135265700483092 1.70814186402734 0.0037235987465767 0.0459378758409191 GO:0017124 SH3 domain binding 18/1476 115/18639 0.156521739130435 1.97656415694592 0.00400773639281043 0.0486769046617871 GO:0003727 single-stranded RNA binding 15/1476 89/18639 0.168539325842697 2.1283228281721 0.00406999776890134 0.0486769046617871 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/1476 41/18639 0.219512195121951 2.77201070791196 0.0041171655044331 0.0486769046617871 GO:0061650 ubiquitin-like protein conjugating enzyme activity 9/1476 41/18639 0.219512195121951 2.77201070791196 0.0041171655044331 0.0486769046617871 GO:0051010 microtubule plus-end binding 6/1476 21/18639 0.285714285714286 3.60801393728223 0.0046929824676043 0.0545115518688503 GO:0000287 magnesium ion binding 30/1476 230/18639 0.130434782608696 1.64713679745493 0.00470672430233245 0.0545115518688503 GO:0035198 miRNA binding 9/1476 42/18639 0.214285714285714 2.70601045296167 0.00487910517138431 0.0553778436952119 GO:0043175 RNA polymerase core enzyme binding 9/1476 42/18639 0.214285714285714 2.70601045296167 0.00487910517138431 0.0553778436952119 GO:0010485 histone H4 acetyltransferase activity 8/1476 35/18639 0.228571428571429 2.88641114982578 0.00516920653783702 0.0571275510942481 GO:0046966 nuclear thyroid hormone receptor binding 7/1476 28/18639 0.25 3.15701219512195 0.00518426234599785 0.0571275510942481 GO:0141052 histone H3 demethylase activity 7/1476 28/18639 0.25 3.15701219512195 0.00518426234599785 0.0571275510942481 GO:0005131 growth hormone receptor binding 4/1476 10/18639 0.4 5.05121951219512 0.00557682887412751 0.0602828644965212 GO:0050815 phosphoserine residue binding 4/1476 10/18639 0.4 5.05121951219512 0.00557682887412751 0.0602828644965212 GO:0000993 RNA polymerase II complex binding 8/1476 36/18639 0.222222222222222 2.80623306233062 0.00619394665161873 0.0663219759395024 GO:0005024 transforming growth factor beta receptor activity 5/1476 16/18639 0.3125 3.94626524390244 0.00644550834841781 0.0677375182912427 GO:0030275 LRR domain binding 5/1476 16/18639 0.3125 3.94626524390244 0.00644550834841781 0.0677375182912427 GO:0030295 protein kinase activator activity 20/1476 139/18639 0.143884892086331 1.81698543604141 0.006620589254571 0.0682602539066963 GO:0001223 transcription coactivator binding 9/1476 44/18639 0.204545454545455 2.58300997782705 0.00672718926240848 0.0682602539066963 GO:0043014 alpha-tubulin binding 9/1476 44/18639 0.204545454545455 2.58300997782705 0.00672718926240848 0.0682602539066963 GO:0008017 microtubule binding 34/1476 276/18639 0.123188405797101 1.55562919759632 0.00673581360136563 0.0682602539066963 GO:0044013 histone H2B acetyltransferase activity 6/1476 23/18639 0.260869565217391 3.29427359490986 0.00761720572503873 0.0752609064245115 GO:0070577 lysine-acetylated histone binding 6/1476 23/18639 0.260869565217391 3.29427359490986 0.00761720572503873 0.0752609064245115 GO:0032452 histone demethylase activity 7/1476 30/18639 0.233333333333333 2.94654471544715 0.007758172732747 0.0752609064245115 GO:0051721 protein phosphatase 2A binding 7/1476 30/18639 0.233333333333333 2.94654471544715 0.007758172732747 0.0752609064245115 GO:0070566 adenylyltransferase activity 7/1476 30/18639 0.233333333333333 2.94654471544715 0.007758172732747 0.0752609064245115 GO:0043522 leucine zipper domain binding 4/1476 11/18639 0.363636363636364 4.5920177383592 0.00821932210981797 0.0783943747449025 GO:0097493 structural molecule activity conferring elasticity 4/1476 11/18639 0.363636363636364 4.5920177383592 0.00821932210981797 0.0783943747449025 GO:0101005 deubiquitinase activity 17/1476 115/18639 0.147826086956522 1.86675503711559 0.0090090827363265 0.0852109075477548 GO:0008013 beta-catenin binding 16/1476 106/18639 0.150943396226415 1.90612057063967 0.0091137993271114 0.0854889441014168 GO:0140457 protein demethylase activity 7/1476 31/18639 0.225806451612903 2.8514948859166 0.0093504832711877 0.0869901517442462 GO:0050699 WW domain binding 6/1476 24/18639 0.25 3.15701219512195 0.00948860752159306 0.0875574759106351 GO:0019888 protein phosphatase regulator activity 16/1476 107/18639 0.149532710280374 1.88830635969911 0.00995154258990594 0.0910887164479294 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 5/1476 18/18639 0.277777777777778 3.50779132791328 0.0110723060164846 0.0995541061921762 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 5/1476 18/18639 0.277777777777778 3.50779132791328 0.0110723060164846 0.0995541061921762 GO:0005025 transforming growth factor beta receptor activity, type I 4/1476 12/18639 0.333333333333333 4.20934959349593 0.011565633800999 0.0995541061921762 GO:0005026 transforming growth factor beta receptor activity, type II 4/1476 12/18639 0.333333333333333 4.20934959349593 0.011565633800999 0.0995541061921762 GO:0016361 activin receptor activity, type I 4/1476 12/18639 0.333333333333333 4.20934959349593 0.011565633800999 0.0995541061921762 GO:0016362 activin receptor activity, type II 4/1476 12/18639 0.333333333333333 4.20934959349593 0.011565633800999 0.0995541061921762 GO:0017002 activin receptor activity 4/1476 12/18639 0.333333333333333 4.20934959349593 0.011565633800999 0.0995541061921762 GO:0008139 nuclear localization sequence binding 6/1476 25/18639 0.24 3.03073170731707 0.0116658115626074 0.0995541061921762 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 6/1476 25/18639 0.24 3.03073170731707 0.0116658115626074 0.0995541061921762 GO:0019207 kinase regulator activity 34/1476 287/18639 0.118466898954704 1.49600577887312 0.0119255696432544 0.101011354814133 GO:0030165 PDZ domain binding 13/1476 83/18639 0.156626506024096 1.97788715838966 0.0131918169007418 0.110908979128459 GO:0032182 ubiquitin-like protein binding 17/1476 120/18639 0.141666666666667 1.78897357723577 0.0135329718502855 0.112163560548968 GO:0140767 enzyme-substrate adaptor activity 19/1476 139/18639 0.136690647482014 1.72613616423934 0.0135386852821221 0.112163560548968 GO:0034987 immunoglobulin receptor binding 5/1476 19/18639 0.263157894736842 3.32317073170732 0.0140657112582725 0.114082727480243 GO:1990380 K48-linked deubiquitinase activity 5/1476 19/18639 0.263157894736842 3.32317073170732 0.0140657112582725 0.114082727480243 GO:0005160 transforming growth factor beta receptor binding 6/1476 26/18639 0.230769230769231 2.91416510318949 0.0141723916957835 0.114082727480243 GO:0052742 phosphatidylinositol kinase activity 6/1476 26/18639 0.230769230769231 2.91416510318949 0.0141723916957835 0.114082727480243 GO:0004713 protein tyrosine kinase activity 19/1476 140/18639 0.135714285714286 1.71380662020906 0.0145394434243395 0.116213156948065 GO:0046975 histone H3K36 methyltransferase activity 4/1476 13/18639 0.307692307692308 3.88555347091933 0.0156747926966673 0.124162249208565 GO:0004402 histone acetyltransferase activity 8/1476 42/18639 0.19047619047619 2.40534262485482 0.0158621375640898 0.124162249208565 GO:0048487 beta-tubulin binding 8/1476 42/18639 0.19047619047619 2.40534262485482 0.0158621375640898 0.124162249208565 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 6/1476 27/18639 0.222222222222222 2.80623306233062 0.0170306804079712 0.132396042897584 GO:0015095 magnesium ion transmembrane transporter activity 5/1476 20/18639 0.25 3.15701219512195 0.017557813740682 0.133913083595413 GO:0052745 inositol phosphate phosphatase activity 5/1476 20/18639 0.25 3.15701219512195 0.017557813740682 0.133913083595413 GO:0005048 signal sequence binding 9/1476 51/18639 0.176470588235294 2.22847919655667 0.0175797792561379 0.133913083595413 GO:0061631 ubiquitin conjugating enzyme activity 7/1476 35/18639 0.2 2.52560975609756 0.018146922723538 0.136608748651066 GO:0004712 protein serine/threonine/tyrosine kinase activity 8/1476 43/18639 0.186046511627907 2.3494044242768 0.0181743797764854 0.136608748651066 GO:0001098 basal transcription machinery binding 10/1476 60/18639 0.166666666666667 2.10467479674797 0.0186003207834023 0.137982771824586 GO:0001099 basal RNA polymerase II transcription machinery binding 10/1476 60/18639 0.166666666666667 2.10467479674797 0.0186003207834023 0.137982771824586 GO:0035401 histone H3Y41 kinase activity 16/1476 115/18639 0.139130434782609 1.75694591728526 0.0190472422837578 0.139474967690743 GO:0140801 histone H2AXY142 kinase activity 16/1476 115/18639 0.139130434782609 1.75694591728526 0.0190472422837578 0.139474967690743 GO:0097718 disordered domain specific binding 6/1476 28/18639 0.214285714285714 2.70601045296167 0.0202615216976003 0.147011282247546 GO:0005545 1-phosphatidylinositol binding 4/1476 14/18639 0.285714285714286 3.60801393728223 0.0205945320505373 0.147011282247546 GO:0032454 histone H3K9 demethylase activity 4/1476 14/18639 0.285714285714286 3.60801393728223 0.0205945320505373 0.147011282247546 GO:0098821 BMP receptor activity 4/1476 14/18639 0.285714285714286 3.60801393728223 0.0205945320505373 0.147011282247546 GO:0019838 growth factor binding 18/1476 136/18639 0.132352941176471 1.6713593974175 0.0215391817304991 0.151179712579283 GO:0044325 transmembrane transporter binding 18/1476 136/18639 0.132352941176471 1.6713593974175 0.0215391817304991 0.151179712579283 GO:0010314 phosphatidylinositol-5-phosphate binding 5/1476 21/18639 0.238095238095238 3.00667828106852 0.0215780735135188 0.151179712579283 GO:0042826 histone deacetylase binding 17/1476 127/18639 0.133858267716535 1.69036873439601 0.0226454556171441 0.157684614266617 GO:0004843 cysteine-type deubiquitinase activity 15/1476 108/18639 0.138888888888889 1.75389566395664 0.0230283082624123 0.158406847744473 GO:0005496 steroid binding 15/1476 108/18639 0.138888888888889 1.75389566395664 0.0230283082624123 0.158406847744473 GO:0140104 molecular carrier activity 29/1476 249/18639 0.116465863453815 1.47073660495641 0.0234425667034503 0.159745916036291 GO:0140303 intramembrane lipid transporter activity 8/1476 45/18639 0.177777777777778 2.2449864498645 0.0235044651789079 0.159745916036291 GO:0043130 ubiquitin binding 14/1476 100/18639 0.14 1.76792682926829 0.0258319584633266 0.161317421853439 GO:0035591 signaling adaptor activity 17/1476 129/18639 0.131782945736434 1.66416146719607 0.0259528779891673 0.161317421853439 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0032931 histone H3K56 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0043992 histone H3K9 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0043993 histone H3K18 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0043994 histone H3K23 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0043999 histone H2AK5 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0044012 histone H2AK9 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0044014 histone H2BK5 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0044015 histone H2BK12 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0044016 histone H3K4 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0044017 histone H3K27 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0044018 histone H3K36 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0046972 histone H4K16 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0050321 tau-protein kinase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0140908 histone H3K122 acetyltransferase activity 5/1476 22/18639 0.227272727272727 2.8700110864745 0.0261518992255795 0.161317421853439 GO:0120283 protein serine/threonine kinase binding 4/1476 15/18639 0.266666666666667 3.36747967479675 0.0263611509543423 0.161729223422587 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 7/1476 38/18639 0.184210526315789 2.32621951219512 0.0277264420448814 0.167640847011207 GO:0008187 poly-pyrimidine tract binding 6/1476 30/18639 0.2 2.52560975609756 0.0279155243040689 0.167640847011207 GO:0031624 ubiquitin conjugating enzyme binding 6/1476 30/18639 0.2 2.52560975609756 0.0279155243040689 0.167640847011207 GO:0035925 mRNA 3'-UTR AU-rich region binding 6/1476 30/18639 0.2 2.52560975609756 0.0279155243040689 0.167640847011207 GO:0061733 protein-lysine-acetyltransferase activity 8/1476 47/18639 0.170212765957447 2.14945511157239 0.0298449729444497 0.178284443641844 GO:0031491 nucleosome binding 11/1476 74/18639 0.148648648648649 1.87714238628873 0.0306158378865509 0.181931811524792 GO:0019887 protein kinase regulator activity 29/1476 255/18639 0.113725490196078 1.43613103778097 0.030959840131195 0.183017804942221 GO:0070273 phosphatidylinositol-4-phosphate binding 6/1476 31/18639 0.193548387096774 2.4441384736428 0.0323711341519604 0.190369104986917 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 4/1476 16/18639 0.25 3.15701219512195 0.0329996984896504 0.192075168132068 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 4/1476 16/18639 0.25 3.15701219512195 0.0329996984896504 0.192075168132068 GO:0004532 RNA exonuclease activity 7/1476 40/18639 0.175 2.20990853658537 0.0357336779499157 0.205876773975403 GO:0032451 demethylase activity 7/1476 40/18639 0.175 2.20990853658537 0.0357336779499157 0.205876773975403 GO:0004721 phosphoprotein phosphatase activity 21/1476 175/18639 0.12 1.51536585365854 0.0366562540755068 0.208122911596448 GO:0030215 semaphorin receptor binding 5/1476 24/18639 0.208333333333333 2.63084349593496 0.0370403772180463 0.208122911596448 GO:0043998 histone H2A acetyltransferase activity 5/1476 24/18639 0.208333333333333 2.63084349593496 0.0370403772180463 0.208122911596448 GO:0050431 transforming growth factor beta binding 5/1476 24/18639 0.208333333333333 2.63084349593496 0.0370403772180463 0.208122911596448 GO:0070840 dynein complex binding 5/1476 24/18639 0.208333333333333 2.63084349593496 0.0370403772180463 0.208122911596448 GO:0140142 nucleocytoplasmic carrier activity 6/1476 32/18639 0.1875 2.36775914634146 0.0372639170095569 0.208347516284961 GO:0004386 helicase activity 19/1476 155/18639 0.12258064516129 1.54795436664044 0.037586154730332 0.209119047151602 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/1476 10/18639 0.3 3.78841463414634 0.0389963852133518 0.212792775082472 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/1476 10/18639 0.3 3.78841463414634 0.0389963852133518 0.212792775082472 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1476 10/18639 0.3 3.78841463414634 0.0389963852133518 0.212792775082472 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 3/1476 10/18639 0.3 3.78841463414634 0.0389963852133518 0.212792775082472 GO:0003724 RNA helicase activity 11/1476 77/18639 0.142857142857143 1.80400696864112 0.0395248700357531 0.213931155587856 GO:0001727 lipid kinase activity 7/1476 41/18639 0.170731707317073 2.15600832837597 0.0402555845937702 0.213931155587856 GO:0016877 ligase activity, forming carbon-sulfur bonds 7/1476 41/18639 0.170731707317073 2.15600832837597 0.0402555845937702 0.213931155587856 GO:0017080 sodium channel regulator activity 7/1476 41/18639 0.170731707317073 2.15600832837597 0.0402555845937702 0.213931155587856 GO:0140789 histone phosphatase activity 17/1476 136/18639 0.125 1.57850609756098 0.0404126263662195 0.213931155587856 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 4/1476 17/18639 0.235294117647059 2.9713055954089 0.0405244039219287 0.213931155587856 GO:0046965 nuclear retinoid X receptor binding 4/1476 17/18639 0.235294117647059 2.9713055954089 0.0405244039219287 0.213931155587856 GO:0004879 nuclear receptor activity 9/1476 59/18639 0.152542372881356 1.92631252583712 0.0414162346075517 0.216624084237655 GO:0045309 protein phosphorylated amino acid binding 9/1476 59/18639 0.152542372881356 1.92631252583712 0.0414162346075517 0.216624084237655 GO:0071889 14-3-3 protein binding 6/1476 33/18639 0.181818181818182 2.2960088691796 0.0426046466723884 0.221817770519086 GO:0003707 nuclear steroid receptor activity 5/1476 25/18639 0.2 2.52560975609756 0.0433840186319061 0.223822096123697 GO:0019211 phosphatase activator activity 5/1476 25/18639 0.2 2.52560975609756 0.0433840186319061 0.223822096123697 GO:0002039 p53 binding 10/1476 69/18639 0.144927536231884 1.83015199717215 0.0443579251415225 0.227811063509629 GO:0098531 ligand-modulated transcription factor activity 9/1476 60/18639 0.15 1.89420731707317 0.0454425723412251 0.232330268501309 GO:0008186 ATP-dependent activity, acting on RNA 11/1476 79/18639 0.139240506329114 1.75833590614387 0.0463780986665326 0.236049964065087 GO:0000900 mRNA regulatory element binding translation repressor activity 4/1476 18/18639 0.222222222222222 2.80623306233062 0.0489392890377698 0.243623215166091 GO:0017128 phospholipid scramblase activity 4/1476 18/18639 0.222222222222222 2.80623306233062 0.0489392890377698 0.243623215166091 GO:0031690 adrenergic receptor binding 4/1476 18/18639 0.222222222222222 2.80623306233062 0.0489392890377698 0.243623215166091 GO:0050811 GABA receptor binding 4/1476 18/18639 0.222222222222222 2.80623306233062 0.0489392890377698 0.243623215166091 GO:1990381 ubiquitin-specific protease binding 4/1476 18/18639 0.222222222222222 2.80623306233062 0.0489392890377698 0.243623215166091 GO:0030507 spectrin binding 5/1476 26/18639 0.192307692307692 2.42847091932458 0.0503391679024114 0.245129849147846 GO:0097602 cullin family protein binding 5/1476 26/18639 0.192307692307692 2.42847091932458 0.0503391679024114 0.245129849147846 GO:0005114 type II transforming growth factor beta receptor binding 3/1476 11/18639 0.272727272727273 3.4440133037694 0.050537783877177 0.245129849147846 GO:0008432 JUN kinase binding 3/1476 11/18639 0.272727272727273 3.4440133037694 0.050537783877177 0.245129849147846 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/1476 11/18639 0.272727272727273 3.4440133037694 0.050537783877177 0.245129849147846 GO:0048407 platelet-derived growth factor binding 3/1476 11/18639 0.272727272727273 3.4440133037694 0.050537783877177 0.245129849147846 GO:0000175 3'-5'-RNA exonuclease activity 6/1476 35/18639 0.171428571428571 2.16480836236934 0.054661400037493 0.262884275604045 GO:0005154 epidermal growth factor receptor binding 6/1476 35/18639 0.171428571428571 2.16480836236934 0.054661400037493 0.262884275604045 GO:0034212 protein N-acetyltransferase activity 8/1476 53/18639 0.150943396226415 1.90612057063967 0.0556144850398971 0.265220338320518 GO:0051018 protein kinase A binding 8/1476 53/18639 0.150943396226415 1.90612057063967 0.0556144850398971 0.265220338320518 GO:0005385 zinc ion transmembrane transporter activity 5/1476 27/18639 0.185185185185185 2.33852755194219 0.0579092786966024 0.272726271040015 GO:0008266 poly(U) RNA binding 5/1476 27/18639 0.185185185185185 2.33852755194219 0.0579092786966024 0.272726271040015 GO:0023026 MHC class II protein complex binding 5/1476 27/18639 0.185185185185185 2.33852755194219 0.0579092786966024 0.272726271040015 GO:0042577 lipid phosphatase activity 4/1476 19/18639 0.210526315789474 2.65853658536585 0.0582389097789691 0.272844116919964 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 15/1476 122/18639 0.122950819672131 1.55262894842063 0.0584150840630408 0.272844116919964 GO:0061775 cohesin loader activity 18/1476 153/18639 0.117647058823529 1.48565279770445 0.058765254971658 0.27335477210177 GO:0051287 NAD binding 8/1476 54/18639 0.148148148148148 1.87082204155375 0.0609600114437709 0.276263786000319 GO:0043539 protein serine/threonine kinase activator activity 10/1476 73/18639 0.136986301369863 1.72986969595723 0.0612034815834342 0.276263786000319 GO:0044390 ubiquitin-like protein conjugating enzyme binding 6/1476 36/18639 0.166666666666667 2.10467479674797 0.0613872552761223 0.276263786000319 GO:0004715 non-membrane spanning protein tyrosine kinase activity 7/1476 45/18639 0.155555555555556 1.96436314363144 0.0619712178865171 0.276263786000319 GO:0046915 transition metal ion transmembrane transporter activity 7/1476 45/18639 0.155555555555556 1.96436314363144 0.0619712178865171 0.276263786000319 GO:0051219 phosphoprotein binding 12/1476 93/18639 0.129032258064516 1.6294256490952 0.0629328873513718 0.276263786000319 GO:0008603 cAMP-dependent protein kinase regulator activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0035197 siRNA binding 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0035497 cAMP response element binding 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0070410 co-SMAD binding 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:1990817 poly(A) RNA polymerase activity 3/1476 12/18639 0.25 3.15701219512195 0.0635285005692363 0.276263786000319 GO:0036408 histone H3K14 acetyltransferase activity 5/1476 28/18639 0.178571428571429 2.25500871080139 0.0660935736963855 0.285232722986303 GO:0045499 chemorepellent activity 5/1476 28/18639 0.178571428571429 2.25500871080139 0.0660935736963855 0.285232722986303 GO:0008374 O-acyltransferase activity 8/1476 55/18639 0.145454545454545 1.83680709534368 0.0666165593056085 0.286400737923734 GO:0051015 actin filament binding 23/1476 209/18639 0.110047846889952 1.38968957871397 0.0676359715097682 0.289686142126743 GO:0061608 nuclear import signal receptor activity 4/1476 20/18639 0.2 2.52560975609756 0.0684091837885408 0.291532318745254 GO:0023023 MHC protein complex binding 6/1476 37/18639 0.162162162162162 2.04779169413316 0.0685807304889717 0.291532318745254 GO:0140597 protein carrier chaperone 21/1476 188/18639 0.111702127659574 1.41057991696938 0.068952809987572 0.292020296029456 GO:0003924 GTPase activity 34/1476 331/18639 0.102719033232628 1.29714096234618 0.0711096870596211 0.300035296701375 GO:0003785 actin monomer binding 5/1476 29/18639 0.172413793103448 2.17724978973928 0.0748872236352565 0.312883178627524 GO:0010484 histone H3 acetyltransferase activity 5/1476 29/18639 0.172413793103448 2.17724978973928 0.0748872236352565 0.312883178627524 GO:0140938 histone H3 methyltransferase activity 7/1476 47/18639 0.148936170212766 1.88077322262584 0.0750649273570513 0.312883178627524 GO:0140658 ATP-dependent chromatin remodeler activity 18/1476 158/18639 0.113924050632911 1.43863846866317 0.0752573636698803 0.312883178627524 GO:0098631 cell adhesion mediator activity 10/1476 76/18639 0.131578947368421 1.66158536585366 0.0762392831750818 0.314667026779967 GO:0042162 telomeric DNA binding 6/1476 38/18639 0.157894736842105 1.99390243902439 0.0762409095722387 0.314667026779967 GO:0046974 histone H3K9 methyltransferase activity 3/1476 13/18639 0.230769230769231 2.91416510318949 0.077884612931007 0.317982142721917 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/1476 13/18639 0.230769230769231 2.91416510318949 0.077884612931007 0.317982142721917 GO:0140852 histone ubiquitin ligase activity 3/1476 13/18639 0.230769230769231 2.91416510318949 0.077884612931007 0.317982142721917 GO:1990782 protein tyrosine kinase binding 14/1476 117/18639 0.11965811965812 1.51104857202418 0.0786955680857503 0.320141468735938 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 4/1476 21/18639 0.19047619047619 2.40534262485482 0.0794282685591343 0.320822365888318 GO:0072542 protein phosphatase activator activity 4/1476 21/18639 0.19047619047619 2.40534262485482 0.0794282685591343 0.320822365888318 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 7/1476 48/18639 0.145833333333333 1.84159044715447 0.0821753931171065 0.32957268970995 GO:0140693 molecular condensate scaffold activity 7/1476 48/18639 0.145833333333333 1.84159044715447 0.0821753931171065 0.32957268970995 GO:0033612 receptor serine/threonine kinase binding 5/1476 30/18639 0.166666666666667 2.10467479674797 0.0842815635014941 0.333308622209742 GO:0043995 histone H4K5 acetyltransferase activity 5/1476 30/18639 0.166666666666667 2.10467479674797 0.0842815635014941 0.333308622209742 GO:0043996 histone H4K8 acetyltransferase activity 5/1476 30/18639 0.166666666666667 2.10467479674797 0.0842815635014941 0.333308622209742 GO:0043997 histone H4K12 acetyltransferase activity 5/1476 30/18639 0.166666666666667 2.10467479674797 0.0842815635014941 0.333308622209742 GO:0032934 sterol binding 9/1476 68/18639 0.132352941176471 1.6713593974175 0.0870313218229524 0.341823679333405 GO:0004197 cysteine-type endopeptidase activity 11/1476 88/18639 0.125 1.57850609756098 0.0870370425791666 0.341823679333405 GO:0019199 transmembrane receptor protein kinase activity 10/1476 78/18639 0.128205128205128 1.61898061288305 0.0874340082537587 0.342198618510401 GO:0000510 H3-H4 histone complex chaperone activity 17/1476 151/18639 0.112582781456954 1.42170085608141 0.0892222076508512 0.344446277835769 GO:0140584 chromatin extrusion motor activity 17/1476 151/18639 0.112582781456954 1.42170085608141 0.0892222076508512 0.344446277835769 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 17/1476 151/18639 0.112582781456954 1.42170085608141 0.0892222076508512 0.344446277835769 GO:0140849 ATP-dependent H2AZ histone chaperone activity 17/1476 151/18639 0.112582781456954 1.42170085608141 0.0892222076508512 0.344446277835769 GO:0070034 telomerase RNA binding 4/1476 22/18639 0.181818181818182 2.2960088691796 0.0912674617443685 0.35114769179613 GO:0071949 FAD binding 6/1476 40/18639 0.15 1.89420731707317 0.092946563439066 0.351433509284052 GO:0015616 DNA translocase activity 17/1476 152/18639 0.111842105263158 1.41234756097561 0.0934315644873818 0.351433509284052 GO:0140674 ATP-dependent histone chaperone activity 17/1476 152/18639 0.111842105263158 1.41234756097561 0.0934315644873818 0.351433509284052 GO:0008195 phosphatidate phosphatase activity 3/1476 14/18639 0.214285714285714 2.70601045296167 0.0935091804438624 0.351433509284052 GO:0008494 translation activator activity 3/1476 14/18639 0.214285714285714 2.70601045296167 0.0935091804438624 0.351433509284052 GO:0044548 S100 protein binding 3/1476 14/18639 0.214285714285714 2.70601045296167 0.0935091804438624 0.351433509284052 GO:0046030 inositol trisphosphate phosphatase activity 3/1476 14/18639 0.214285714285714 2.70601045296167 0.0935091804438624 0.351433509284052 GO:0016878 acid-thiol ligase activity 5/1476 31/18639 0.161290322580645 2.036782061369 0.0942643383764044 0.353102389627785 GO:0140713 histone chaperone activity 18/1476 164/18639 0.109756097560976 1.38600535395598 0.0987851506706542 0.368819559247344 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/1476 60/18639 0.133333333333333 1.68373983739837 0.0995968570550846 0.37063092707384 GO:0097110 scaffold protein binding 9/1476 70/18639 0.128571428571429 1.623606271777 0.100100830773978 0.37128902917799 GO:0019001 guanyl nucleotide binding 39/1476 400/18639 0.0975 1.23123475609756 0.103116526344772 0.375923102974353 GO:0032561 guanyl ribonucleotide binding 39/1476 400/18639 0.0975 1.23123475609756 0.103116526344772 0.375923102974353 GO:0042171 lysophosphatidic acid acyltransferase activity 4/1476 23/18639 0.173913043478261 2.19618239660657 0.103892101017299 0.375923102974353 GO:0071617 lysophospholipid acyltransferase activity 4/1476 23/18639 0.173913043478261 2.19618239660657 0.103892101017299 0.375923102974353 GO:0140103 catalytic activity, acting on a glycoprotein 4/1476 23/18639 0.173913043478261 2.19618239660657 0.103892101017299 0.375923102974353 GO:0008234 cysteine-type peptidase activity 20/1476 187/18639 0.106951871657754 1.35059345245859 0.104097797839432 0.375923102974353 GO:0033192 calmodulin-dependent protein phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0140791 histone H2AXS140 phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/1476 81/18639 0.123456790123457 1.55901836796146 0.105987130354003 0.375923102974353 GO:0043021 ribonucleoprotein complex binding 19/1476 177/18639 0.107344632768362 1.35555325892242 0.108032281731165 0.3819833014482 GO:0004559 alpha-mannosidase activity 3/1476 15/18639 0.2 2.52560975609756 0.110296187816242 0.385188225142877 GO:0005402 carbohydrate:monoatomic cation symporter activity 3/1476 15/18639 0.2 2.52560975609756 0.110296187816242 0.385188225142877 GO:0042809 nuclear vitamin D receptor binding 3/1476 15/18639 0.2 2.52560975609756 0.110296187816242 0.385188225142877 GO:0061578 K63-linked deubiquitinase activity 3/1476 15/18639 0.2 2.52560975609756 0.110296187816242 0.385188225142877 GO:0031492 nucleosomal DNA binding 6/1476 42/18639 0.142857142857143 1.80400696864112 0.111453474114685 0.388035868466771 GO:0005319 lipid transporter activity 19/1476 178/18639 0.106741573033708 1.34793779117566 0.112451553894622 0.388581473769365 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/1476 82/18639 0.121951219512195 1.54000594883998 0.112637273013323 0.388581473769365 GO:0033549 MAP kinase phosphatase activity 10/1476 82/18639 0.121951219512195 1.54000594883998 0.112637273013323 0.388581473769365 GO:0005518 collagen binding 9/1476 72/18639 0.125 1.57850609756098 0.114232232167175 0.391984008659082 GO:0030159 signaling receptor complex adaptor activity 7/1476 52/18639 0.134615384615385 1.6999296435272 0.11431427917723 0.391984008659082 GO:0140416 transcription regulator inhibitor activity 5/1476 33/18639 0.151515151515152 1.91334072431633 0.115929851479013 0.396326450086384 GO:0016887 ATP hydrolysis activity 40/1476 417/18639 0.0959232613908873 1.21132362402761 0.119026146597692 0.404589089304116 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/1476 83/18639 0.120481927710843 1.52145166029974 0.11951716564448 0.404589089304116 GO:0002020 protease binding 15/1476 136/18639 0.110294117647059 1.39279949784792 0.119772629080337 0.404589089304116 GO:0016779 nucleotidyltransferase activity 15/1476 136/18639 0.110294117647059 1.39279949784792 0.119772629080337 0.404589089304116 GO:0140296 general transcription initiation factor binding 7/1476 53/18639 0.132075471698113 1.66785549930971 0.123246856545955 0.415089561363972 GO:0017018 myosin phosphatase activity 10/1476 84/18639 0.119047619047619 1.50333914053426 0.12662415609888 0.415519735689165 GO:0051117 ATPase binding 10/1476 84/18639 0.119047619047619 1.50333914053426 0.12662415609888 0.415519735689165 GO:0015035 protein-disulfide reductase activity 5/1476 34/18639 0.147058823529412 1.85706599713056 0.127572623224515 0.415519735689165 GO:0030332 cyclin binding 5/1476 34/18639 0.147058823529412 1.85706599713056 0.127572623224515 0.415519735689165 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0004707 MAP kinase activity 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0004708 MAP kinase kinase activity 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0008142 oxysterol binding 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0015923 mannosidase activity 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0034450 ubiquitin-ubiquitin ligase activity 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0043023 ribosomal large subunit binding 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0070411 I-SMAD binding 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0140327 flippase activity 3/1476 16/18639 0.1875 2.36775914634146 0.128133839199302 0.415519735689165 GO:0008276 protein methyltransferase activity 11/1476 95/18639 0.115789473684211 1.46219512195122 0.13022694578336 0.419820835348678 GO:0017056 structural constituent of nuclear pore 4/1476 25/18639 0.16 2.02048780487805 0.131334527138148 0.419820835348678 GO:0019706 protein-cysteine S-palmitoyltransferase activity 4/1476 25/18639 0.16 2.02048780487805 0.131334527138148 0.419820835348678 GO:0019707 protein-cysteine S-acyltransferase activity 4/1476 25/18639 0.16 2.02048780487805 0.131334527138148 0.419820835348678 GO:0003689 DNA clamp loader activity 17/1476 160/18639 0.10625 1.34173018292683 0.131566998988774 0.419820835348678 GO:0016248 channel inhibitor activity 6/1476 44/18639 0.136363636363636 1.7220066518847 0.131679486682052 0.419820835348678 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1476 54/18639 0.12962962962963 1.63696928635953 0.13252362071011 0.421328598055951 GO:0016407 acetyltransferase activity 11/1476 96/18639 0.114583333333333 1.44696392276423 0.137210245822082 0.435010136894031 GO:0140566 histone reader activity 5/1476 35/18639 0.142857142857143 1.80400696864112 0.139724493755685 0.441747354910036 GO:0098632 cell-cell adhesion mediator activity 7/1476 55/18639 0.127272727272727 1.60720620842572 0.142135067164933 0.447094300525429 GO:0141110 transporter inhibitor activity 6/1476 45/18639 0.133333333333333 1.68373983739837 0.142403835727519 0.447094300525429 GO:0005525 GTP binding 36/1476 378/18639 0.0952380952380952 1.20267131242741 0.142597477348199 0.447094300525429 GO:0050681 nuclear androgen receptor binding 4/1476 26/18639 0.153846153846154 1.94277673545966 0.146060956090099 0.455437321874348 GO:0070412 R-SMAD binding 4/1476 26/18639 0.153846153846154 1.94277673545966 0.146060956090099 0.455437321874348 GO:0038191 neuropilin binding 3/1476 17/18639 0.176470588235294 2.22847919655667 0.146907289615882 0.455573152224116 GO:0051787 misfolded protein binding 3/1476 17/18639 0.176470588235294 2.22847919655667 0.146907289615882 0.455573152224116 GO:0004725 protein tyrosine phosphatase activity 11/1476 98/18639 0.112244897959184 1.41743404678945 0.151761899328362 0.468639753576825 GO:0005484 SNAP receptor activity 5/1476 36/18639 0.138888888888889 1.75389566395664 0.152359532220131 0.468639753576825 GO:0016409 palmitoyltransferase activity 5/1476 36/18639 0.138888888888889 1.75389566395664 0.152359532220131 0.468639753576825 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1476 46/18639 0.130434782608696 1.64713679745493 0.153514905007201 0.470917343738306 GO:0042054 histone methyltransferase activity 8/1476 67/18639 0.119402985074627 1.50782672005825 0.158480961668455 0.484840677880584 GO:0008094 ATP-dependent activity, acting on DNA 21/1476 210/18639 0.1 1.26280487804878 0.159424385165088 0.486415798823588 GO:0003697 single-stranded DNA binding 13/1476 121/18639 0.107438016528926 1.35673251360613 0.161105717508061 0.487179680168654 GO:0001671 ATPase activator activity 4/1476 27/18639 0.148148148148148 1.87082204155375 0.161391682593316 0.487179680168654 GO:0016405 CoA-ligase activity 4/1476 27/18639 0.148148148148148 1.87082204155375 0.161391682593316 0.487179680168654 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/1476 27/18639 0.148148148148148 1.87082204155375 0.161391682593316 0.487179680168654 GO:0043495 protein-membrane adaptor activity 6/1476 47/18639 0.127659574468085 1.61209133367929 0.164995389541369 0.495442579914002 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/1476 89/18639 0.112359550561798 1.41888188544807 0.165438535495513 0.495442579914002 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/1476 89/18639 0.112359550561798 1.41888188544807 0.165438535495513 0.495442579914002 GO:0003746 translation elongation factor activity 3/1476 18/18639 0.166666666666667 2.10467479674797 0.166500889731505 0.496006587520362 GO:0022851 GABA-gated chloride ion channel activity 3/1476 18/18639 0.166666666666667 2.10467479674797 0.166500889731505 0.496006587520362 GO:0030145 manganese ion binding 8/1476 68/18639 0.117647058823529 1.48565279770445 0.168007580314523 0.499184826327181 GO:0140793 histone H2AXY142 phosphatase activity 10/1476 90/18639 0.111111111111111 1.40311653116531 0.173825428193707 0.515122352480046 GO:0043022 ribosome binding 12/1476 112/18639 0.107142857142857 1.35300522648084 0.17541581243562 0.51848163311049 GO:0008080 N-acetyltransferase activity 8/1476 69/18639 0.115942028985507 1.46412159773772 0.177787940837716 0.519651991308595 GO:0016279 protein-lysine N-methyltransferase activity 8/1476 69/18639 0.115942028985507 1.46412159773772 0.177787940837716 0.519651991308595 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0004955 prostaglandin receptor activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0008140 cAMP response element binding protein binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0042975 peroxisome proliferator activated receptor binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0043208 glycosphingolipid binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0045322 unmethylated CpG binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0070097 delta-catenin binding 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0140999 histone H3K4 trimethyltransferase activity 2/1476 10/18639 0.2 2.52560975609756 0.184861185558263 0.519651991308595 GO:0004890 GABA-A receptor activity 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0008381 mechanosensitive monoatomic ion channel activity 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0008574 plus-end-directed microtubule motor activity 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0030506 ankyrin binding 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0042800 histone H3K4 methyltransferase activity 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0097001 ceramide binding 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0140036 ubiquitin-modified protein reader activity 3/1476 19/18639 0.157894736842105 1.99390243902439 0.186800010972605 0.519651991308595 GO:0016278 lysine N-methyltransferase activity 8/1476 70/18639 0.114285714285714 1.44320557491289 0.187812084071747 0.521190013255338 GO:0015101 organic cation transmembrane transporter activity 9/1476 81/18639 0.111111111111111 1.40311653116531 0.190113474915461 0.525009231214229 GO:0030971 receptor tyrosine kinase binding 9/1476 81/18639 0.111111111111111 1.40311653116531 0.190113474915461 0.525009231214229 GO:0003730 mRNA 3'-UTR binding 25/1476 262/18639 0.0954198473282443 1.20496648668777 0.191251281998519 0.526869429777473 GO:0016417 S-acyltransferase activity 4/1476 29/18639 0.137931034482759 1.74179983179142 0.193656697080012 0.530918722671049 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1476 29/18639 0.137931034482759 1.74179983179142 0.193656697080012 0.530918722671049 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/1476 60/18639 0.116666666666667 1.47327235772358 0.194810797046489 0.532795794331965 GO:0140299 molecular sensor activity 8/1476 71/18639 0.112676056338028 1.42287873582961 0.198069494776875 0.540405953297482 GO:0015291 secondary active transmembrane transporter activity 27/1476 287/18639 0.0940766550522648 1.18800458910512 0.200189893063144 0.544881363613114 GO:0016836 hydro-lyase activity 7/1476 61/18639 0.114754098360656 1.44912035185926 0.206177447159989 0.550105626359099 GO:0015036 disulfide oxidoreductase activity 5/1476 40/18639 0.125 1.57850609756098 0.207154528735015 0.550105626359099 GO:0030331 nuclear estrogen receptor binding 5/1476 40/18639 0.125 1.57850609756098 0.207154528735015 0.550105626359099 GO:0061791 GTPase motor activity 5/1476 40/18639 0.125 1.57850609756098 0.207154528735015 0.550105626359099 GO:1990606 membrane scission GTPase motor activity 5/1476 40/18639 0.125 1.57850609756098 0.207154528735015 0.550105626359099 GO:0000339 RNA cap binding 3/1476 20/18639 0.15 1.89420731707317 0.20769250988744 0.550105626359099 GO:0043024 ribosomal small subunit binding 3/1476 20/18639 0.15 1.89420731707317 0.20769250988744 0.550105626359099 GO:0008135 translation factor activity, RNA binding 9/1476 83/18639 0.108433734939759 1.36930649426976 0.209413085802527 0.550105626359099 GO:0070851 growth factor receptor binding 14/1476 139/18639 0.100719424460432 1.27188980522899 0.21085390194084 0.550105626359099 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 13/1476 128/18639 0.1015625 1.28253620426829 0.213201631135786 0.550105626359099 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0004016 adenylate cyclase activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0004954 prostanoid receptor activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0005225 volume-sensitive anion channel activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0008172 S-methyltransferase activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0008503 benzodiazepine receptor activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0019107 myristoyltransferase activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0019215 intermediate filament binding 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0032050 clathrin heavy chain binding 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0034056 estrogen response element binding 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0047676 arachidonate-CoA ligase activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0070697 activin receptor binding 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0140537 transcription regulator activator activity 2/1476 11/18639 0.181818181818182 2.2960088691796 0.214710830376283 0.550105626359099 GO:0004527 exonuclease activity 9/1476 84/18639 0.107142857142857 1.35300522648084 0.219347757366965 0.559460010362933 GO:0180051 translation factor activity 9/1476 84/18639 0.107142857142857 1.35300522648084 0.219347757366965 0.559460010362933 GO:0016411 acylglycerol O-acyltransferase activity 4/1476 31/18639 0.129032258064516 1.6294256490952 0.227701315126895 0.579464109123377 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/1476 21/18639 0.142857142857143 1.80400696864112 0.229069883442157 0.580344459167073 GO:0035613 RNA stem-loop binding 3/1476 21/18639 0.142857142857143 1.80400696864112 0.229069883442157 0.580344459167073 GO:0000340 RNA 7-methylguanosine cap binding 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0004300 enoyl-CoA hydratase activity 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0005049 nuclear export signal receptor activity 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0005078 MAP-kinase scaffold activity 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0005247 voltage-gated chloride channel activity 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0016208 AMP binding 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0034452 dynactin binding 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0045295 gamma-catenin binding 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0097677 STAT family protein binding 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/1476 12/18639 0.166666666666667 2.10467479674797 0.244947296337692 0.60122100375636 GO:0008378 galactosyltransferase activity 4/1476 32/18639 0.125 1.57850609756098 0.245255792721758 0.60122100375636 GO:0043425 bHLH transcription factor binding 4/1476 32/18639 0.125 1.57850609756098 0.245255792721758 0.60122100375636 GO:0051059 NF-kappaB binding 4/1476 32/18639 0.125 1.57850609756098 0.245255792721758 0.60122100375636 GO:0120015 sterol transfer activity 4/1476 32/18639 0.125 1.57850609756098 0.245255792721758 0.60122100375636 GO:0008170 N-methyltransferase activity 10/1476 98/18639 0.102040816326531 1.28857640617222 0.247391767564618 0.605150121090176 GO:0042277 peptide binding 23/1476 249/18639 0.0923694779116466 1.16644627289646 0.24961717069418 0.609280620941708 GO:0008093 cytoskeletal anchor activity 3/1476 22/18639 0.136363636363636 1.7220066518847 0.250828160552335 0.609614480143255 GO:0140035 ubiquitin-like protein reader activity 3/1476 22/18639 0.136363636363636 1.7220066518847 0.250828160552335 0.609614480143255 GO:0008200 ion channel inhibitor activity 5/1476 43/18639 0.116279069767442 1.468377765173 0.251841274419489 0.610768902705385 GO:0017022 myosin binding 8/1476 76/18639 0.105263157894737 1.32926829268293 0.252455062570394 0.610952017094663 GO:0003925 G protein activity 6/1476 54/18639 0.111111111111111 1.40311653116531 0.254039765174659 0.612176504189464 GO:0140463 chromatin-protein adaptor activity 6/1476 54/18639 0.111111111111111 1.40311653116531 0.254039765174659 0.612176504189464 GO:0016247 channel regulator activity 16/1476 168/18639 0.0952380952380952 1.20267131242741 0.256470460528904 0.616724518432853 GO:0030296 protein tyrosine kinase activator activity 4/1476 33/18639 0.121212121212121 1.53067257945307 0.263093853582826 0.629982117756345 GO:0140311 protein sequestering activity 4/1476 33/18639 0.121212121212121 1.53067257945307 0.263093853582826 0.629982117756345 GO:0001046 core promoter sequence-specific DNA binding 5/1476 44/18639 0.113636363636364 1.43500554323725 0.267246631821725 0.637080928149356 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1476 44/18639 0.113636363636364 1.43500554323725 0.267246631821725 0.637080928149356 GO:0140313 molecular sequestering activity 6/1476 55/18639 0.109090909090909 1.37760532150776 0.267742381257483 0.637080928149356 GO:0015297 antiporter activity 13/1476 135/18639 0.0962962962962963 1.21603432700994 0.271515776139344 0.637736416717858 GO:0140097 catalytic activity, acting on DNA 30/1476 336/18639 0.0892857142857143 1.1275043554007 0.271709885242816 0.637736416717858 GO:0141108 transporter regulator activity 16/1476 170/18639 0.0941176470588235 1.18852223816356 0.271775280441202 0.637736416717858 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 21/1476 229/18639 0.091703056768559 1.1580306741932 0.272675446237267 0.637736416717858 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1476 23/18639 0.130434782608696 1.64713679745493 0.27286856948259 0.637736416717858 GO:0016917 GABA receptor activity 3/1476 23/18639 0.130434782608696 1.64713679745493 0.27286856948259 0.637736416717858 GO:0017134 fibroblast growth factor binding 3/1476 23/18639 0.130434782608696 1.64713679745493 0.27286856948259 0.637736416717858 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/1476 23/18639 0.130434782608696 1.64713679745493 0.27286856948259 0.637736416717858 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1476 13/18639 0.153846153846154 1.94277673545966 0.275322329684361 0.637736416717858 GO:0030955 potassium ion binding 2/1476 13/18639 0.153846153846154 1.94277673545966 0.275322329684361 0.637736416717858 GO:0031994 insulin-like growth factor I binding 2/1476 13/18639 0.153846153846154 1.94277673545966 0.275322329684361 0.637736416717858 GO:0035673 oligopeptide transmembrane transporter activity 2/1476 13/18639 0.153846153846154 1.94277673545966 0.275322329684361 0.637736416717858 GO:0071714 icosanoid transmembrane transporter activity 2/1476 13/18639 0.153846153846154 1.94277673545966 0.275322329684361 0.637736416717858 GO:0050840 extracellular matrix binding 7/1476 67/18639 0.104477611940299 1.31934838005096 0.278922324156377 0.64475934402747 GO:0016831 carboxy-lyase activity 4/1476 34/18639 0.117647058823529 1.48565279770445 0.281163350963934 0.647303049379442 GO:0051427 hormone receptor binding 4/1476 34/18639 0.117647058823529 1.48565279770445 0.281163350963934 0.647303049379442 GO:0099106 ion channel regulator activity 15/1476 160/18639 0.09375 1.18387957317073 0.285454373155054 0.65585164682386 GO:0016835 carbon-oxygen lyase activity 8/1476 79/18639 0.10126582278481 1.27878974992282 0.287121745580635 0.657636354622223 GO:0008201 heparin binding 16/1476 172/18639 0.0930232558139535 1.1747022121384 0.287389984046364 0.657636354622223 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0004622 lysophospholipase activity 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0005315 phosphate transmembrane transporter activity 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0015295 solute:proton symporter activity 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0048027 mRNA 5'-UTR binding 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0140612 DNA damage sensor activity 3/1476 24/18639 0.125 1.57850609756098 0.295098015726225 0.665877232304702 GO:0004722 protein serine/threonine phosphatase activity 10/1476 103/18639 0.0970873786407767 1.22602415344542 0.298071159159775 0.671251519139572 GO:0043178 alcohol binding 9/1476 92/18639 0.0978260869565217 1.2353525980912 0.304383807988246 0.676186806217827 GO:0005161 platelet-derived growth factor receptor binding 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0005344 oxygen carrier activity 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0008559 ABC-type xenobiotic transporter activity 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0030983 mismatched DNA binding 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0034236 protein kinase A catalytic subunit binding 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0061665 SUMO ligase activity 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0070742 C2H2 zinc finger domain binding 2/1476 14/18639 0.142857142857143 1.80400696864112 0.305624521224445 0.676186806217827 GO:0008408 3'-5' exonuclease activity 6/1476 58/18639 0.103448275862069 1.30634987384357 0.309827033597043 0.684151134499307 GO:0001618 virus receptor activity 8/1476 81/18639 0.0987654320987654 1.24721469436917 0.310865128400764 0.685110525698771 GO:0001784 phosphotyrosine residue binding 5/1476 47/18639 0.106382978723404 1.34340944473275 0.314533058136095 0.69019611035582 GO:0140359 ABC-type transporter activity 5/1476 47/18639 0.106382978723404 1.34340944473275 0.314533058136095 0.69019611035582 GO:0051213 dioxygenase activity 9/1476 93/18639 0.0967741935483871 1.2220692368214 0.315553513387113 0.69019611035582 GO:0008483 transaminase activity 3/1476 25/18639 0.12 1.51536585365854 0.31742940053369 0.69019611035582 GO:0015645 fatty acid ligase activity 3/1476 25/18639 0.12 1.51536585365854 0.31742940053369 0.69019611035582 GO:0017025 TBP-class protein binding 3/1476 25/18639 0.12 1.51536585365854 0.31742940053369 0.69019611035582 GO:0120515 fatty acid-CoA ligase activity 3/1476 25/18639 0.12 1.51536585365854 0.31742940053369 0.69019611035582 GO:0140272 exogenous protein binding 8/1476 82/18639 0.0975609756097561 1.23200475907198 0.322886727641501 0.700719762663679 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/1476 59/18639 0.101694915254237 1.28420835055808 0.324105282225294 0.702021937644483 GO:0005254 chloride channel activity 8/1476 83/18639 0.0963855421686747 1.21716132823979 0.334990582770992 0.712133016175888 GO:0004467 long-chain fatty acid-CoA ligase activity 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0004953 icosanoid receptor activity 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0005041 low-density lipoprotein particle receptor activity 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0030553 cGMP binding 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0045504 dynein heavy chain binding 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0048531 beta-1,3-galactosyltransferase activity 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0050780 dopamine receptor binding 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0051371 muscle alpha-actinin binding 2/1476 15/18639 0.133333333333333 1.68373983739837 0.335675034056476 0.712133016175888 GO:0008157 protein phosphatase 1 binding 3/1476 26/18639 0.115384615384615 1.45708255159475 0.33978180633068 0.716825929712495 GO:0050750 low-density lipoprotein particle receptor binding 3/1476 26/18639 0.115384615384615 1.45708255159475 0.33978180633068 0.716825929712495 GO:0070006 metalloaminopeptidase activity 3/1476 26/18639 0.115384615384615 1.45708255159475 0.33978180633068 0.716825929712495 GO:0016763 pentosyltransferase activity 5/1476 49/18639 0.102040816326531 1.28857640617222 0.346631288593827 0.728567615840729 GO:0060590 ATPase regulator activity 5/1476 49/18639 0.102040816326531 1.28857640617222 0.346631288593827 0.728567615840729 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 41/1476 484/18639 0.0847107438016529 1.06973140495868 0.348264654231824 0.730647657214641 GO:0015026 coreceptor activity 6/1476 61/18639 0.0983606557377049 1.24210315873651 0.352903396749402 0.737652588048934 GO:0019905 syntaxin binding 6/1476 61/18639 0.0983606557377049 1.24210315873651 0.352903396749402 0.737652588048934 GO:0008320 protein transmembrane transporter activity 3/1476 27/18639 0.111111111111111 1.40311653116531 0.36208057179785 0.755268644741502 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1476 16/18639 0.125 1.57850609756098 0.365323776178929 0.755268644741502 GO:0005521 lamin binding 2/1476 16/18639 0.125 1.57850609756098 0.365323776178929 0.755268644741502 GO:0015562 efflux transmembrane transporter activity 2/1476 16/18639 0.125 1.57850609756098 0.365323776178929 0.755268644741502 GO:0016722 oxidoreductase activity, acting on metal ions 2/1476 16/18639 0.125 1.57850609756098 0.365323776178929 0.755268644741502 GO:0022858 alanine transmembrane transporter activity 2/1476 16/18639 0.125 1.57850609756098 0.365323776178929 0.755268644741502 GO:0050660 flavin adenine dinucleotide binding 8/1476 86/18639 0.0930232558139535 1.1747022121384 0.371664452708193 0.766980279679634 GO:0005272 sodium channel activity 5/1476 51/18639 0.0980392156862745 1.23804399808704 0.37890596799829 0.780505033898473 GO:0008081 phosphoric diester hydrolase activity 8/1476 87/18639 0.0919540229885057 1.16119988786095 0.383966797129221 0.781598581771071 GO:0001216 DNA-binding transcription activator activity 41/1476 491/18639 0.0835030549898167 1.05448065173116 0.384066802172413 0.781598581771071 GO:0019789 SUMO transferase activity 3/1476 28/18639 0.107142857142857 1.35300522648084 0.384257276324456 0.781598581771071 GO:0046625 sphingolipid binding 3/1476 28/18639 0.107142857142857 1.35300522648084 0.384257276324456 0.781598581771071 GO:0051393 alpha-actinin binding 3/1476 28/18639 0.107142857142857 1.35300522648084 0.384257276324456 0.781598581771071 GO:0051537 2 iron, 2 sulfur cluster binding 3/1476 28/18639 0.107142857142857 1.35300522648084 0.384257276324456 0.781598581771071 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1476 28/18639 0.107142857142857 1.35300522648084 0.384257276324456 0.781598581771071 GO:0004177 aminopeptidase activity 4/1476 40/18639 0.1 1.26280487804878 0.391725221442312 0.792170936490997 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1476 17/18639 0.117647058823529 1.48565279770445 0.394445974387335 0.792170936490997 GO:0008484 sulfuric ester hydrolase activity 2/1476 17/18639 0.117647058823529 1.48565279770445 0.394445974387335 0.792170936490997 GO:0031489 myosin V binding 2/1476 17/18639 0.117647058823529 1.48565279770445 0.394445974387335 0.792170936490997 GO:0032183 SUMO binding 2/1476 17/18639 0.117647058823529 1.48565279770445 0.394445974387335 0.792170936490997 GO:0070403 NAD+ binding 2/1476 17/18639 0.117647058823529 1.48565279770445 0.394445974387335 0.792170936490997 GO:1990226 histone methyltransferase binding 2/1476 17/18639 0.117647058823529 1.48565279770445 0.394445974387335 0.792170936490997 GO:0005080 protein kinase C binding 5/1476 52/18639 0.0961538461538462 1.21423545966229 0.395038546303 0.792170936490997 GO:0004629 phospholipase C activity 3/1476 29/18639 0.103448275862069 1.30634987384357 0.406249650852661 0.807519008262294 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/1476 29/18639 0.103448275862069 1.30634987384357 0.406249650852661 0.807519008262294 GO:0035250 UDP-galactosyltransferase activity 3/1476 29/18639 0.103448275862069 1.30634987384357 0.406249650852661 0.807519008262294 GO:0043236 laminin binding 3/1476 29/18639 0.103448275862069 1.30634987384357 0.406249650852661 0.807519008262294 GO:0097472 cyclin-dependent protein kinase activity 3/1476 29/18639 0.103448275862069 1.30634987384357 0.406249650852661 0.807519008262294 GO:0140318 protein transporter activity 4/1476 41/18639 0.0975609756097561 1.23200475907198 0.410099602244522 0.810130597709511 GO:0005003 ephrin receptor activity 5/1476 53/18639 0.0943396226415094 1.19132535664979 0.41113235619443 0.810130597709511 GO:0005005 transmembrane-ephrin receptor activity 5/1476 53/18639 0.0943396226415094 1.19132535664979 0.41113235619443 0.810130597709511 GO:0005544 calcium-dependent phospholipid binding 5/1476 53/18639 0.0943396226415094 1.19132535664979 0.41113235619443 0.810130597709511 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1476 53/18639 0.0943396226415094 1.19132535664979 0.41113235619443 0.810130597709511 GO:0008308 voltage-gated monoatomic anion channel activity 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0015280 ligand-gated sodium channel activity 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0017075 syntaxin-1 binding 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0030228 lipoprotein particle receptor activity 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0070064 proline-rich region binding 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0070628 proteasome binding 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1476 18/18639 0.111111111111111 1.40311653116531 0.422939109969314 0.823389176355355 GO:0015485 cholesterol binding 5/1476 54/18639 0.0925925925925926 1.16926377597109 0.427162212420938 0.826842631670609 GO:0050661 NADP binding 5/1476 54/18639 0.0925925925925926 1.16926377597109 0.427162212420938 0.826842631670609 GO:0015215 nucleotide transmembrane transporter activity 3/1476 30/18639 0.1 1.26280487804878 0.428001429757682 0.826842631670609 GO:0016769 transferase activity, transferring nitrogenous groups 3/1476 30/18639 0.1 1.26280487804878 0.428001429757682 0.826842631670609 GO:0019894 kinesin binding 4/1476 42/18639 0.0952380952380952 1.20267131242741 0.428355477905126 0.826842631670609 GO:0005253 monoatomic anion channel activity 9/1476 103/18639 0.087378640776699 1.10342173810088 0.430150857958629 0.8288985123651 GO:0015103 inorganic anion transmembrane transporter activity 14/1476 165/18639 0.0848484848484849 1.07147080561715 0.434464623800712 0.835792115277641 GO:0003774 cytoskeletal motor activity 13/1476 153/18639 0.0849673202614379 1.07297146500877 0.437797025015796 0.840777704556562 GO:0070325 lipoprotein particle receptor binding 3/1476 31/18639 0.0967741935483871 1.2220692368214 0.449462156325266 0.85689682545871 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1476 19/18639 0.105263157894737 1.32926829268293 0.450720180439515 0.85689682545871 GO:0005520 insulin-like growth factor binding 2/1476 19/18639 0.105263157894737 1.32926829268293 0.450720180439515 0.85689682545871 GO:0015245 fatty acid transmembrane transporter activity 2/1476 19/18639 0.105263157894737 1.32926829268293 0.450720180439515 0.85689682545871 GO:0031420 alkali metal ion binding 2/1476 19/18639 0.105263157894737 1.32926829268293 0.450720180439515 0.85689682545871 GO:0046624 sphingolipid transporter activity 2/1476 19/18639 0.105263157894737 1.32926829268293 0.450720180439515 0.85689682545871 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 14/1476 167/18639 0.0838323353293413 1.05863881992113 0.452674886594107 0.85749546605528 GO:0003777 microtubule motor activity 6/1476 68/18639 0.0882352941176471 1.11423959827834 0.454057070572003 0.85749546605528 GO:0005548 phospholipid transporter activity 6/1476 68/18639 0.0882352941176471 1.11423959827834 0.454057070572003 0.85749546605528 GO:1990841 promoter-specific chromatin binding 6/1476 68/18639 0.0882352941176471 1.11423959827834 0.454057070572003 0.85749546605528 GO:0019205 nucleobase-containing compound kinase activity 4/1476 44/18639 0.0909090909090909 1.1480044345898 0.46438078547082 0.874544793566997 GO:0000149 SNARE binding 9/1476 106/18639 0.0849056603773585 1.07219282098481 0.464626000458942 0.874544793566997 GO:0022804 active transmembrane transporter activity 37/1476 457/18639 0.0809628008752735 1.02240219885787 0.468967303999926 0.879927827274673 GO:0016410 N-acyltransferase activity 8/1476 94/18639 0.0851063829787234 1.0747275557862 0.46991394308142 0.879927827274673 GO:0022884 macromolecule transmembrane transporter activity 3/1476 32/18639 0.09375 1.18387957317073 0.470586952560112 0.879927827274673 GO:0042910 xenobiotic transmembrane transporter activity 3/1476 32/18639 0.09375 1.18387957317073 0.470586952560112 0.879927827274673 GO:0030742 GTP-dependent protein binding 2/1476 20/18639 0.1 1.26280487804878 0.477723254945302 0.890338085981802 GO:0140939 histone H4 methyltransferase activity 2/1476 20/18639 0.1 1.26280487804878 0.477723254945302 0.890338085981802 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1476 70/18639 0.0857142857142857 1.08240418118467 0.48244022768927 0.897655177749707 GO:0004518 nuclease activity 17/1476 209/18639 0.0813397129186603 1.02716186252772 0.490979521986546 0.899609348203386 GO:0019239 deaminase activity 3/1476 33/18639 0.0909090909090909 1.1480044345898 0.49133626245784 0.899609348203386 GO:0004540 RNA nuclease activity 10/1476 121/18639 0.0826446280991736 1.04364039508164 0.492109095826653 0.899609348203386 GO:0015108 chloride transmembrane transporter activity 10/1476 121/18639 0.0826446280991736 1.04364039508164 0.492109095826653 0.899609348203386 GO:0030276 clathrin binding 4/1476 46/18639 0.0869565217391304 1.09809119830329 0.499563876245072 0.899609348203386 GO:0004860 protein kinase inhibitor activity 7/1476 84/18639 0.0833333333333333 1.05233739837398 0.501627652599094 0.899609348203386 GO:0005123 death receptor binding 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0005248 voltage-gated sodium channel activity 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0008373 sialyltransferase activity 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0009975 cyclase activity 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0015125 bile acid transmembrane transporter activity 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0061891 calcium ion sensor activity 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0140312 cargo adaptor activity 2/1476 21/18639 0.0952380952380952 1.20267131242741 0.503897294050895 0.899609348203386 GO:0001786 phosphatidylserine binding 5/1476 59/18639 0.0847457627118644 1.07017362546507 0.505560946144184 0.899609348203386 GO:0015459 potassium channel regulator activity 5/1476 59/18639 0.0847457627118644 1.07017362546507 0.505560946144184 0.899609348203386 GO:0090482 vitamin transmembrane transporter activity 3/1476 34/18639 0.0882352941176471 1.11423959827834 0.511675576473379 0.899609348203386 GO:0099095 ligand-gated monoatomic anion channel activity 4/1476 47/18639 0.0851063829787234 1.0747275557862 0.516776045371488 0.899609348203386 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/1476 60/18639 0.0833333333333333 1.05233739837398 0.520750910690559 0.899609348203386 GO:1902936 phosphatidylinositol bisphosphate binding 9/1476 111/18639 0.0810810810810811 1.02389584706658 0.521064219810569 0.899609348203386 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/1476 86/18639 0.0813953488372093 1.0278644356211 0.527039126665538 0.899609348203386 GO:0016209 antioxidant activity 7/1476 86/18639 0.0813953488372093 1.0278644356211 0.527039126665538 0.899609348203386 GO:0008970 phospholipase A1 activity 2/1476 22/18639 0.0909090909090909 1.1480044345898 0.529204207400752 0.899609348203386 GO:0016881 acid-amino acid ligase activity 2/1476 22/18639 0.0909090909090909 1.1480044345898 0.529204207400752 0.899609348203386 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1476 22/18639 0.0909090909090909 1.1480044345898 0.529204207400752 0.899609348203386 GO:0061133 endopeptidase activator activity 2/1476 22/18639 0.0909090909090909 1.1480044345898 0.529204207400752 0.899609348203386 GO:0140784 metal ion sensor activity 2/1476 22/18639 0.0909090909090909 1.1480044345898 0.529204207400752 0.899609348203386 GO:0043015 gamma-tubulin binding 3/1476 35/18639 0.0857142857142857 1.08240418118467 0.531575143697048 0.899609348203386 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1476 48/18639 0.0833333333333333 1.05233739837398 0.533706102979208 0.899609348203386 GO:0036121 double-stranded DNA helicase activity 4/1476 48/18639 0.0833333333333333 1.05233739837398 0.533706102979208 0.899609348203386 GO:0016741 transferase activity, transferring one-carbon groups 17/1476 215/18639 0.0790697674418605 0.99849688031764 0.539368447254248 0.899609348203386 GO:0005004 GPI-linked ephrin receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0005008 hepatocyte growth factor receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0005009 insulin receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0005011 macrophage colony-stimulating factor receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0005020 stem cell factor receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0008288 boss receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0036332 placental growth factor receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0038062 protein tyrosine kinase collagen receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0060175 brain-derived neurotrophic factor receptor activity 4/1476 49/18639 0.0816326530612245 1.03086112493778 0.550334975369019 0.899609348203386 GO:0005539 glycosaminoglycan binding 19/1476 242/18639 0.0785123966942149 0.991458375327555 0.550399478947114 0.899609348203386 GO:0015179 L-amino acid transmembrane transporter activity 5/1476 62/18639 0.0806451612903226 1.0183910306845 0.550505468708155 0.899609348203386 GO:0004190 aspartic-type endopeptidase activity 3/1476 36/18639 0.0833333333333333 1.05233739837398 0.551009677185779 0.899609348203386 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/1476 36/18639 0.0833333333333333 1.05233739837398 0.551009677185779 0.899609348203386 GO:0045505 dynein intermediate chain binding 3/1476 36/18639 0.0833333333333333 1.05233739837398 0.551009677185779 0.899609348203386 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/1476 88/18639 0.0795454545454545 1.00450388026608 0.551939400719764 0.899609348203386 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1476 23/18639 0.0869565217391304 1.09809119830329 0.55361712529772 0.899609348203386 GO:0003887 DNA-directed DNA polymerase activity 2/1476 23/18639 0.0869565217391304 1.09809119830329 0.55361712529772 0.899609348203386 GO:0005158 insulin receptor binding 2/1476 23/18639 0.0869565217391304 1.09809119830329 0.55361712529772 0.899609348203386 GO:0008171 O-methyltransferase activity 2/1476 23/18639 0.0869565217391304 1.09809119830329 0.55361712529772 0.899609348203386 GO:0016849 phosphorus-oxygen lyase activity 2/1476 23/18639 0.0869565217391304 1.09809119830329 0.55361712529772 0.899609348203386 GO:0031681 G-protein beta-subunit binding 2/1476 23/18639 0.0869565217391304 1.09809119830329 0.55361712529772 0.899609348203386 GO:0008168 methyltransferase activity 16/1476 204/18639 0.0784313725490196 0.990435198469632 0.553826231804046 0.899609348203386 GO:0001094 TFIID-class transcription factor complex binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0004382 GDP phosphatase activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0005381 iron ion transmembrane transporter activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0005522 profilin binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0008190 eukaryotic initiation factor 4E binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0015187 glycine transmembrane transporter activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0015203 polyamine transmembrane transporter activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0015279 store-operated calcium channel activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0015643 toxic substance binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0019911 structural constituent of myelin sheath 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0030957 Tat protein binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0031419 cobalamin binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0031720 haptoglobin binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0031996 thioesterase binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0043121 neurotrophin binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0051864 histone H3K36 demethylase activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0051880 G-quadruplex DNA binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0070513 death domain binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0098505 G-rich strand telomeric DNA binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0141109 transporter activator activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:1905394 retromer complex binding 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:1990757 ubiquitin ligase activator activity 1/1476 10/18639 0.1 1.26280487804878 0.561857140348012 0.899609348203386 GO:0051536 iron-sulfur cluster binding 6/1476 76/18639 0.0789473684210526 0.996951219512195 0.564342534276595 0.899609348203386 GO:0005006 epidermal growth factor receptor activity 4/1476 50/18639 0.08 1.01024390243902 0.566645753535016 0.899609348203386 GO:0005007 fibroblast growth factor receptor activity 4/1476 50/18639 0.08 1.01024390243902 0.566645753535016 0.899609348203386 GO:0005017 platelet-derived growth factor receptor activity 4/1476 50/18639 0.08 1.01024390243902 0.566645753535016 0.899609348203386 GO:0005019 platelet-derived growth factor beta-receptor activity 4/1476 50/18639 0.08 1.01024390243902 0.566645753535016 0.899609348203386 GO:0015605 organophosphate ester transmembrane transporter activity 4/1476 50/18639 0.08 1.01024390243902 0.566645753535016 0.899609348203386 GO:0032813 tumor necrosis factor receptor superfamily binding 4/1476 50/18639 0.08 1.01024390243902 0.566645753535016 0.899609348203386 GO:0016874 ligase activity 13/1476 167/18639 0.0778443113772455 0.983021761355338 0.567423235984671 0.899609348203386 GO:0030551 cyclic nucleotide binding 3/1476 37/18639 0.0810810810810811 1.02389584706658 0.569958056972452 0.899609348203386 GO:0042805 actinin binding 3/1476 37/18639 0.0810810810810811 1.02389584706658 0.569958056972452 0.899609348203386 GO:0070001 aspartic-type peptidase activity 3/1476 37/18639 0.0810810810810811 1.02389584706658 0.569958056972452 0.899609348203386 GO:0019210 kinase inhibitor activity 7/1476 90/18639 0.0777777777777778 0.982181571815718 0.576255334974564 0.899609348203386 GO:0005540 hyaluronic acid binding 2/1476 24/18639 0.0833333333333333 1.05233739837398 0.577118862531491 0.899609348203386 GO:0030552 cAMP binding 2/1476 24/18639 0.0833333333333333 1.05233739837398 0.577118862531491 0.899609348203386 GO:0035035 histone acetyltransferase binding 2/1476 24/18639 0.0833333333333333 1.05233739837398 0.577118862531491 0.899609348203386 GO:0070300 phosphatidic acid binding 2/1476 24/18639 0.0833333333333333 1.05233739837398 0.577118862531491 0.899609348203386 GO:0051540 metal cluster binding 6/1476 77/18639 0.0779220779220779 0.984003801076972 0.577391001204565 0.899609348203386 GO:0005010 insulin-like growth factor receptor activity 4/1476 51/18639 0.0784313725490196 0.990435198469632 0.582623607623249 0.899609348203386 GO:0005021 vascular endothelial growth factor receptor activity 4/1476 51/18639 0.0784313725490196 0.990435198469632 0.582623607623249 0.899609348203386 GO:0005030 neurotrophin receptor activity 4/1476 51/18639 0.0784313725490196 0.990435198469632 0.582623607623249 0.899609348203386 GO:0016830 carbon-carbon lyase activity 4/1476 51/18639 0.0784313725490196 0.990435198469632 0.582623607623249 0.899609348203386 GO:0042887 amide transmembrane transporter activity 3/1476 38/18639 0.0789473684210526 0.996951219512195 0.588403034474932 0.899609348203386 GO:0120013 lipid transfer activity 5/1476 65/18639 0.0769230769230769 0.971388367729831 0.593373553538857 0.899609348203386 GO:0019955 cytokine binding 11/1476 144/18639 0.0763888888888889 0.964642615176152 0.594548649573946 0.899609348203386 GO:0005262 calcium channel activity 10/1476 131/18639 0.0763358778625954 0.963973189350214 0.595278791347128 0.899609348203386 GO:0002162 dystroglycan binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0008199 ferric iron binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0010854 adenylate cyclase regulator activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0015217 ADP transmembrane transporter activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0019206 nucleoside kinase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0032794 GTPase activating protein binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0034713 type I transforming growth factor beta receptor binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0035252 UDP-xylosyltransferase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0042285 xylosyltransferase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0045294 alpha-catenin binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0050998 nitric-oxide synthase binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0070990 snRNP binding 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0180030 inositol phosphate kinase activity 1/1476 11/18639 0.0909090909090909 1.1480044345898 0.596571771345185 0.899609348203386 GO:0000030 mannosyltransferase activity 2/1476 25/18639 0.08 1.01024390243902 0.599700554879127 0.899609348203386 GO:0004709 MAP kinase kinase kinase activity 2/1476 25/18639 0.08 1.01024390243902 0.599700554879127 0.899609348203386 GO:0005251 delayed rectifier potassium channel activity 2/1476 25/18639 0.08 1.01024390243902 0.599700554879127 0.899609348203386 GO:0120020 cholesterol transfer activity 2/1476 25/18639 0.08 1.01024390243902 0.599700554879127 0.899609348203386 GO:1901681 sulfur compound binding 21/1476 275/18639 0.0763636363636364 0.964323725055433 0.602058346723187 0.899609348203386 GO:0000217 DNA secondary structure binding 3/1476 39/18639 0.0769230769230769 0.971388367729831 0.606330941333545 0.899609348203386 GO:0004864 protein phosphatase inhibitor activity 4/1476 53/18639 0.0754716981132075 0.953060285319834 0.613531070750045 0.899609348203386 GO:0017046 peptide hormone binding 4/1476 53/18639 0.0754716981132075 0.953060285319834 0.613531070750045 0.899609348203386 GO:0038064 collagen receptor activity 4/1476 53/18639 0.0754716981132075 0.953060285319834 0.613531070750045 0.899609348203386 GO:0004435 phosphatidylinositol phospholipase C activity 2/1476 26/18639 0.0769230769230769 0.971388367729831 0.621360450591497 0.899609348203386 GO:0008198 ferrous iron binding 2/1476 26/18639 0.0769230769230769 0.971388367729831 0.621360450591497 0.899609348203386 GO:0015216 purine nucleotide transmembrane transporter activity 2/1476 26/18639 0.0769230769230769 0.971388367729831 0.621360450591497 0.899609348203386 GO:0034237 protein kinase A regulatory subunit binding 2/1476 26/18639 0.0769230769230769 0.971388367729831 0.621360450591497 0.899609348203386 GO:0043548 phosphatidylinositol 3-kinase binding 2/1476 26/18639 0.0769230769230769 0.971388367729831 0.621360450591497 0.899609348203386 GO:0051139 metal cation:proton antiporter activity 2/1476 26/18639 0.0769230769230769 0.971388367729831 0.621360450591497 0.899609348203386 GO:0001217 DNA-binding transcription repressor activity 21/1476 278/18639 0.0755395683453237 0.953917353921741 0.622263667533469 0.899609348203386 GO:0015085 calcium ion transmembrane transporter activity 11/1476 147/18639 0.0748299319727891 0.944956031192965 0.622286327014213 0.899609348203386 GO:0015144 carbohydrate transmembrane transporter activity 3/1476 40/18639 0.075 0.947103658536585 0.62373140510851 0.899609348203386 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1476 40/18639 0.075 0.947103658536585 0.62373140510851 0.899609348203386 GO:0050997 quaternary ammonium group binding 3/1476 40/18639 0.075 0.947103658536585 0.62373140510851 0.899609348203386 GO:0016829 lyase activity 15/1476 200/18639 0.075 0.947103658536585 0.62542081254079 0.899609348203386 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0004000 adenosine deaminase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0004859 phospholipase inhibitor activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0005165 neurotrophin receptor binding 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0005436 sodium:phosphate symporter activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0008179 adenylate cyclase binding 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0008504 monoamine transmembrane transporter activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0015132 prostaglandin transmembrane transporter activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0016273 arginine N-methyltransferase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0016274 protein-arginine N-methyltransferase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0016840 carbon-nitrogen lyase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0017166 vinculin binding 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0031543 peptidyl-proline dioxygenase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0042301 phosphate ion binding 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0043047 single-stranded telomeric DNA binding 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0070008 serine-type exopeptidase activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0140900 chloride:bicarbonate antiporter activity 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1476 12/18639 0.0833333333333333 1.05233739837398 0.628537632709502 0.899609348203386 GO:0005178 integrin binding 12/1476 161/18639 0.0745341614906832 0.941221027117103 0.629372677587812 0.899670011413308 GO:0008509 monoatomic anion transmembrane transporter activity 11/1476 149/18639 0.0738255033557047 0.932272057619905 0.640234970487136 0.90741007760601 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/1476 41/18639 0.0731707317073171 0.924003569303986 0.640597073755666 0.90741007760601 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/1476 41/18639 0.0731707317073171 0.924003569303986 0.640597073755666 0.90741007760601 GO:0042169 SH2 domain binding 3/1476 41/18639 0.0731707317073171 0.924003569303986 0.640597073755666 0.90741007760601 GO:0004364 glutathione transferase activity 2/1476 27/18639 0.0740740740740741 0.935411020776874 0.642102840894989 0.90741007760601 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/1476 27/18639 0.0740740740740741 0.935411020776874 0.642102840894989 0.90741007760601 GO:0005104 fibroblast growth factor receptor binding 2/1476 27/18639 0.0740740740740741 0.935411020776874 0.642102840894989 0.90741007760601 GO:0008395 steroid hydroxylase activity 2/1476 27/18639 0.0740740740740741 0.935411020776874 0.642102840894989 0.90741007760601 GO:0035255 ionotropic glutamate receptor binding 2/1476 27/18639 0.0740740740740741 0.935411020776874 0.642102840894989 0.90741007760601 GO:0004520 DNA endonuclease activity 3/1476 42/18639 0.0714285714285714 0.902003484320558 0.656923350359554 0.90741007760601 GO:0019212 phosphatase inhibitor activity 4/1476 56/18639 0.0714285714285714 0.902003484320558 0.657133772548022 0.90741007760601 GO:0170055 lipid transmembrane transporter activity 4/1476 56/18639 0.0714285714285714 0.902003484320558 0.657133772548022 0.90741007760601 GO:0005172 vascular endothelial growth factor receptor binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0005542 folic acid binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0008253 5'-nucleotidase activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0008417 fucosyltransferase activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0019855 calcium channel inhibitor activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0043560 insulin receptor substrate binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0045159 myosin II binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0051011 microtubule minus-end binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0061459 L-arginine transmembrane transporter activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0070700 BMP receptor binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0089720 caspase binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0097157 pre-mRNA intronic binding 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0140333 glycerophospholipid flippase activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0140666 annealing activity 1/1476 13/18639 0.0769230769230769 0.971388367729831 0.657972241294931 0.90741007760601 GO:0004857 enzyme inhibitor activity 31/1476 416/18639 0.0745192307692308 0.941032481238274 0.665867010783209 0.914777835528208 GO:0005200 structural constituent of cytoskeleton 8/1476 112/18639 0.0714285714285714 0.902003484320558 0.670566740563882 0.914777835528208 GO:0004601 peroxidase activity 4/1476 57/18639 0.0701754385964912 0.886178861788618 0.670907235426264 0.914777835528208 GO:0015932 nucleobase-containing compound transmembrane transporter activity 4/1476 57/18639 0.0701754385964912 0.886178861788618 0.670907235426264 0.914777835528208 GO:0016504 peptidase activator activity 4/1476 57/18639 0.0701754385964912 0.886178861788618 0.670907235426264 0.914777835528208 GO:0008375 acetylglucosaminyltransferase activity 3/1476 43/18639 0.0697674418604651 0.8810266591038 0.672708139228362 0.914777835528208 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1476 43/18639 0.0697674418604651 0.8810266591038 0.672708139228362 0.914777835528208 GO:0051861 glycolipid binding 2/1476 29/18639 0.0689655172413793 0.870899915895711 0.680876927258653 0.914777835528208 GO:0017116 single-stranded DNA helicase activity 4/1476 58/18639 0.0689655172413793 0.870899915895711 0.684294190086951 0.914777835528208 GO:0004065 arylsulfatase activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0004705 JUN kinase activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0005347 ATP transmembrane transporter activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0008191 metalloendopeptidase inhibitor activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0015386 potassium:proton antiporter activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0015926 glucosidase activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0019992 diacylglycerol binding 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0042813 Wnt receptor activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0043176 amine binding 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0071933 Arp2/3 complex binding 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0098599 palmitoyl hydrolase activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0098847 sequence-specific single stranded DNA binding 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:1901474 azole transmembrane transporter activity 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:1901612 cardiolipin binding 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:1990825 sequence-specific mRNA binding 1/1476 14/18639 0.0714285714285714 0.902003484320558 0.685075912069583 0.914777835528208 GO:0005201 extracellular matrix structural constituent 12/1476 168/18639 0.0714285714285714 0.902003484320558 0.687156529466713 0.916461350582168 GO:0003954 NADH dehydrogenase activity 3/1476 44/18639 0.0681818181818182 0.86100332594235 0.687951604137451 0.916461350582168 GO:0036002 pre-mRNA binding 4/1476 59/18639 0.0677966101694915 0.856138900372055 0.697292971464607 0.9220681790888 GO:0070888 E-box binding 4/1476 59/18639 0.0677966101694915 0.856138900372055 0.697292971464607 0.9220681790888 GO:0001968 fibronectin binding 2/1476 30/18639 0.0666666666666667 0.841869918699187 0.698939462794436 0.9220681790888 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1476 30/18639 0.0666666666666667 0.841869918699187 0.698939462794436 0.9220681790888 GO:0031210 phosphatidylcholine binding 2/1476 30/18639 0.0666666666666667 0.841869918699187 0.698939462794436 0.9220681790888 GO:0042605 peptide antigen binding 3/1476 45/18639 0.0666666666666667 0.841869918699187 0.70265593923986 0.9220681790888 GO:0003678 DNA helicase activity 5/1476 74/18639 0.0675675675675676 0.853246539222149 0.707034213153696 0.9220681790888 GO:0003684 damaged DNA binding 5/1476 74/18639 0.0675675675675676 0.853246539222149 0.707034213153696 0.9220681790888 GO:0000774 adenyl-nucleotide exchange factor activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0004089 carbonate dehydratase activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0005523 tropomyosin binding 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0008252 nucleotidase activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0015929 hexosaminidase activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0017081 chloride channel regulator activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0031386 protein tag activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0033130 acetylcholine receptor binding 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0047372 monoacylglycerol lipase activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0140776 protein-containing complex destabilizing activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0141047 molecular tag activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0141050 histone H3K deacetylase activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0141051 histone H4K deacetylase activity 1/1476 15/18639 0.0666666666666667 0.841869918699187 0.710033117641949 0.9220681790888 GO:0005164 tumor necrosis factor receptor binding 2/1476 31/18639 0.0645161290322581 0.8147128245476 0.716144794275069 0.925593343098622 GO:0005452 solute:inorganic anion antiporter activity 2/1476 31/18639 0.0645161290322581 0.8147128245476 0.716144794275069 0.925593343098622 GO:0008327 methyl-CpG binding 2/1476 31/18639 0.0645161290322581 0.8147128245476 0.716144794275069 0.925593343098622 GO:0017147 Wnt-protein binding 2/1476 31/18639 0.0645161290322581 0.8147128245476 0.716144794275069 0.925593343098622 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1476 46/18639 0.0652173913043478 0.823568398727465 0.71682515293717 0.925593343098622 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/1476 61/18639 0.0655737704918033 0.828068772491004 0.722125281666184 0.930615878479843 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 19/1476 268/18639 0.0708955223880597 0.895272115034583 0.726043638575491 0.930615878479843 GO:0015293 symporter activity 10/1476 146/18639 0.0684931506849315 0.864934847978617 0.728450689419599 0.930615878479843 GO:0005504 fatty acid binding 3/1476 47/18639 0.0638297872340425 0.806045666839647 0.730464864816649 0.930615878479843 GO:0061749 forked DNA-dependent helicase activity 3/1476 47/18639 0.0638297872340425 0.806045666839647 0.730464864816649 0.930615878479843 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/1476 47/18639 0.0638297872340425 0.806045666839647 0.730464864816649 0.930615878479843 GO:0015106 bicarbonate transmembrane transporter activity 2/1476 32/18639 0.0625 0.789253048780488 0.732515317056066 0.930615878479843 GO:0031369 translation initiation factor binding 2/1476 32/18639 0.0625 0.789253048780488 0.732515317056066 0.930615878479843 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1476 32/18639 0.0625 0.789253048780488 0.732515317056066 0.930615878479843 GO:0000062 fatty-acyl-CoA binding 1/1476 16/18639 0.0625 0.789253048780488 0.733013740406149 0.930615878479843 GO:0005159 insulin-like growth factor receptor binding 1/1476 16/18639 0.0625 0.789253048780488 0.733013740406149 0.930615878479843 GO:0055102 lipase inhibitor activity 1/1476 16/18639 0.0625 0.789253048780488 0.733013740406149 0.930615878479843 GO:0097027 ubiquitin-protein transferase activator activity 1/1476 16/18639 0.0625 0.789253048780488 0.733013740406149 0.930615878479843 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1476 16/18639 0.0625 0.789253048780488 0.733013740406149 0.930615878479843 GO:0140328 floppase activity 1/1476 16/18639 0.0625 0.789253048780488 0.733013740406149 0.930615878479843 GO:0046943 carboxylic acid transmembrane transporter activity 13/1476 188/18639 0.0691489361702128 0.873216139076284 0.734327884991475 0.93124262510092 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 6/1476 91/18639 0.0659340659340659 0.832618600911284 0.736422623031104 0.931816808406134 GO:0072341 modified amino acid binding 6/1476 91/18639 0.0659340659340659 0.832618600911284 0.736422623031104 0.931816808406134 GO:0005342 organic acid transmembrane transporter activity 13/1476 189/18639 0.0687830687830688 0.868595947864241 0.741117732907901 0.935505733620699 GO:0009378 four-way junction helicase activity 3/1476 48/18639 0.0625 0.789253048780488 0.743582115605811 0.935505733620699 GO:0043138 3'-5' DNA helicase activity 3/1476 48/18639 0.0625 0.789253048780488 0.743582115605811 0.935505733620699 GO:0008083 growth factor activity 11/1476 162/18639 0.0679012345679012 0.857460102378802 0.744843050568522 0.935505733620699 GO:0005507 copper ion binding 4/1476 63/18639 0.0634920634920635 0.801780874951607 0.745413269486072 0.935505733620699 GO:1901682 sulfur compound transmembrane transporter activity 4/1476 63/18639 0.0634920634920635 0.801780874951607 0.745413269486072 0.935505733620699 GO:0004659 prenyltransferase activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0008569 minus-end-directed microtubule motor activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0015278 intracellularly gated calcium channel activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0017110 nucleoside diphosphate phosphatase activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0019198 transmembrane receptor protein phosphatase activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0030169 low-density lipoprotein particle binding 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0032977 membrane insertase activity 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0036041 long-chain fatty acid binding 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:1901567 fatty acid derivative binding 1/1476 17/18639 0.0588235294117647 0.742826398852224 0.754174225782325 0.935505733620699 GO:0033293 monocarboxylic acid binding 5/1476 79/18639 0.0632911392405063 0.79924359370176 0.759683579644466 0.940103168188571 GO:0008175 tRNA methyltransferase activity 2/1476 34/18639 0.0588235294117647 0.742826398852224 0.762850236036717 0.940103168188571 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/1476 34/18639 0.0588235294117647 0.742826398852224 0.762850236036717 0.940103168188571 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1476 34/18639 0.0588235294117647 0.742826398852224 0.762850236036717 0.940103168188571 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/1476 34/18639 0.0588235294117647 0.742826398852224 0.762850236036717 0.940103168188571 GO:0019825 oxygen binding 2/1476 34/18639 0.0588235294117647 0.742826398852224 0.762850236036717 0.940103168188571 GO:0042562 hormone binding 6/1476 94/18639 0.0638297872340425 0.806045666839647 0.764240688606621 0.940795207774962 GO:0048306 calcium-dependent protein binding 5/1476 80/18639 0.0625 0.789253048780488 0.769308471535364 0.94318212819345 GO:0004620 phospholipase activity 7/1476 109/18639 0.0642201834862385 0.810975609756098 0.769457974560737 0.94318212819345 GO:0000400 four-way junction DNA binding 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:0004706 JUN kinase kinase kinase activity 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:0008409 5'-3' exonuclease activity 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:0016854 racemase and epimerase activity 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:0035615 clathrin adaptor activity 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:1901611 phosphatidylglycerol binding 1/1476 18/18639 0.0555555555555556 0.701558265582656 0.773658644359561 0.94318212819345 GO:0005343 organic acid:sodium symporter activity 2/1476 35/18639 0.0571428571428571 0.721602787456446 0.776866908299727 0.944051328608341 GO:0016229 steroid dehydrogenase activity 2/1476 35/18639 0.0571428571428571 0.721602787456446 0.776866908299727 0.944051328608341 GO:0034061 DNA polymerase activity 2/1476 35/18639 0.0571428571428571 0.721602787456446 0.776866908299727 0.944051328608341 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 12/1476 181/18639 0.0662983425414365 0.837218703678749 0.779086444475426 0.944687260483086 GO:0003743 translation initiation factor activity 3/1476 51/18639 0.0588235294117647 0.742826398852224 0.779887192134495 0.944687260483086 GO:0016597 amino acid binding 3/1476 51/18639 0.0588235294117647 0.742826398852224 0.779887192134495 0.944687260483086 GO:0004896 cytokine receptor activity 6/1476 96/18639 0.0625 0.789253048780488 0.781541988335174 0.944758807151249 GO:0016500 protein-hormone receptor activity 4/1476 67/18639 0.0597014925373134 0.753913360029123 0.787464828145596 0.944758807151249 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1476 67/18639 0.0597014925373134 0.753913360029123 0.787464828145596 0.944758807151249 GO:0055106 ubiquitin-protein transferase regulator activity 2/1476 36/18639 0.0555555555555556 0.701558265582656 0.790152627777018 0.944758807151249 GO:0003756 protein disulfide isomerase activity 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0008301 DNA binding, bending 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0022821 solute:potassium antiporter activity 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0043395 heparan sulfate proteoglycan binding 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0050145 nucleoside monophosphate kinase activity 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0120227 acyl-CoA binding 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0141147 intracellularly calcium-gated channel activity 1/1476 19/18639 0.0526315789473684 0.664634146341463 0.791599670132897 0.944758807151249 GO:0001540 amyloid-beta binding 5/1476 83/18639 0.0602409638554217 0.760725830149868 0.796417713907992 0.948248115574011 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/1476 68/18639 0.0588235294117647 0.742826398852224 0.79706442999334 0.948248115574011 GO:0061135 endopeptidase regulator activity 12/1476 184/18639 0.0652173913043478 0.823568398727465 0.797319425713951 0.948248115574011 GO:0042626 ATPase-coupled transmembrane transporter activity 6/1476 98/18639 0.0612244897959184 0.773145843703335 0.797865154513815 0.948248115574011 GO:0005246 calcium channel regulator activity 3/1476 53/18639 0.0566037735849057 0.714795213989876 0.801656072835845 0.950482498917581 GO:0043394 proteoglycan binding 2/1476 37/18639 0.0540540540540541 0.682597231377719 0.802735174680136 0.950482498917581 GO:0008514 organic anion transmembrane transporter activity 18/1476 269/18639 0.0669144981412639 0.844999546649741 0.804378276694402 0.950482498917581 GO:0001972 retinoic acid binding 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0010851 cyclase regulator activity 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0016004 phospholipase activator activity 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0016505 peptidase activator activity involved in apoptotic process 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0031418 L-ascorbic acid binding 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0140664 ATP-dependent DNA damage sensor activity 1/1476 20/18639 0.05 0.63140243902439 0.80811948145856 0.950482498917581 GO:0017069 snRNA binding 3/1476 54/18639 0.0555555555555556 0.701558265582656 0.811845219507579 0.95387611194731 GO:0031406 carboxylic acid binding 12/1476 187/18639 0.0641711229946524 0.810356071475153 0.814439169898219 0.954199438014453 GO:0005109 frizzled binding 2/1476 38/18639 0.0526315789473684 0.664634146341463 0.814642515802647 0.954199438014453 GO:0043531 ADP binding 2/1476 38/18639 0.0526315789473684 0.664634146341463 0.814642515802647 0.954199438014453 GO:0016298 lipase activity 8/1476 130/18639 0.0615384615384615 0.777110694183865 0.817182034524665 0.956187225964428 GO:0046982 protein heterodimerization activity 25/1476 369/18639 0.0677506775067751 0.855558860466653 0.820101866591092 0.956479243184085 GO:0015294 solute:monoatomic cation symporter activity 7/1476 116/18639 0.0603448275862069 0.762037426408747 0.821618359941693 0.956479243184085 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1476 21/18639 0.0476190476190476 0.601335656213705 0.823330590828943 0.956479243184085 GO:0015174 basic amino acid transmembrane transporter activity 1/1476 21/18639 0.0476190476190476 0.601335656213705 0.823330590828943 0.956479243184085 GO:0036122 BMP binding 1/1476 21/18639 0.0476190476190476 0.601335656213705 0.823330590828943 0.956479243184085 GO:0070182 DNA polymerase binding 1/1476 21/18639 0.0476190476190476 0.601335656213705 0.823330590828943 0.956479243184085 GO:1904047 S-adenosyl-L-methionine binding 1/1476 21/18639 0.0476190476190476 0.601335656213705 0.823330590828943 0.956479243184085 GO:0043177 organic acid binding 12/1476 189/18639 0.0634920634920635 0.801780874951607 0.825242561946629 0.95750710115609 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/1476 39/18639 0.0512820512820513 0.647592245153221 0.825902600909086 0.95750710115609 GO:0004866 endopeptidase inhibitor activity 10/1476 161/18639 0.062111801242236 0.784350855930919 0.829067833211568 0.960080292468356 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 8/1476 132/18639 0.0606060606060606 0.765336289726534 0.829813891551944 0.960080292468356 GO:0030170 pyridoxal phosphate binding 3/1476 56/18639 0.0535714285714286 0.676502613240418 0.830896339191868 0.96034960730892 GO:0005126 cytokine receptor binding 18/1476 275/18639 0.0654545454545455 0.826563192904656 0.831738910999708 0.96034960730892 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/1476 40/18639 0.05 0.63140243902439 0.836543190161747 0.962894682182605 GO:0140662 ATP-dependent protein folding chaperone 2/1476 40/18639 0.05 0.63140243902439 0.836543190161747 0.962894682182605 GO:0004407 histone deacetylase activity 1/1476 22/18639 0.0454545454545455 0.5740022172949 0.837336609087429 0.962894682182605 GO:0033558 protein lysine deacetylase activity 1/1476 22/18639 0.0454545454545455 0.5740022172949 0.837336609087429 0.962894682182605 GO:0070279 vitamin B6 binding 3/1476 57/18639 0.0526315789473684 0.664634146341463 0.839784622734401 0.964732334821402 GO:0051087 protein-folding chaperone binding 8/1476 134/18639 0.0597014925373134 0.753913360029123 0.84175419188301 0.966017196953707 GO:0042287 MHC protein binding 2/1476 41/18639 0.0487804878048781 0.61600237953599 0.846591708951803 0.967918151865342 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1476 41/18639 0.0487804878048781 0.61600237953599 0.846591708951803 0.967918151865342 GO:0048029 monosaccharide binding 4/1476 74/18639 0.0540540540540541 0.682597231377719 0.847505929599249 0.967918151865342 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/1476 58/18639 0.0517241379310345 0.653174936921783 0.848265919060626 0.967918151865342 GO:0005283 amino acid:sodium symporter activity 1/1476 23/18639 0.0434782608695652 0.549045599151644 0.850232949259688 0.967918151865342 GO:0043274 phospholipase binding 1/1476 23/18639 0.0434782608695652 0.549045599151644 0.850232949259688 0.967918151865342 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1476 23/18639 0.0434782608695652 0.549045599151644 0.850232949259688 0.967918151865342 GO:0099186 structural constituent of postsynapse 1/1476 23/18639 0.0434782608695652 0.549045599151644 0.850232949259688 0.967918151865342 GO:0015399 primary active transmembrane transporter activity 10/1476 166/18639 0.0602409638554217 0.760725830149868 0.855394109091715 0.971427663142791 GO:0008307 structural constituent of muscle 2/1476 42/18639 0.0476190476190476 0.601335656213705 0.856075126881415 0.971427663142791 GO:0051879 Hsp90 protein binding 2/1476 42/18639 0.0476190476190476 0.601335656213705 0.856075126881415 0.971427663142791 GO:0016757 glycosyltransferase activity 17/1476 267/18639 0.0636704119850187 0.804033068420572 0.856739287053687 0.971427663142791 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/1476 122/18639 0.0573770491803279 0.724560175929628 0.858561139382543 0.972521849500186 GO:0046873 metal ion transmembrane transporter activity 30/1476 450/18639 0.0666666666666667 0.841869918699187 0.862046019792076 0.972656047578039 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/1476 24/18639 0.0416666666666667 0.526168699186992 0.86210747476961 0.972656047578039 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/1476 24/18639 0.0416666666666667 0.526168699186992 0.86210747476961 0.972656047578039 GO:0060229 lipase activator activity 1/1476 24/18639 0.0416666666666667 0.526168699186992 0.86210747476961 0.972656047578039 GO:0061134 peptidase regulator activity 14/1476 226/18639 0.0619469026548673 0.782268508525793 0.864057340481372 0.972926598321466 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/1476 60/18639 0.05 0.63140243902439 0.864061683795628 0.972926598321466 GO:0005245 voltage-gated calcium channel activity 2/1476 43/18639 0.0465116279069767 0.5873511060692 0.865019857986442 0.973040177219635 GO:0005506 iron ion binding 9/1476 154/18639 0.0584415584415584 0.738002850807729 0.868846624985713 0.973838562224037 GO:0030414 peptidase inhibitor activity 10/1476 169/18639 0.0591715976331361 0.747221821330639 0.869583596041473 0.973838562224037 GO:0001848 complement binding 1/1476 25/18639 0.04 0.505121951219512 0.873041096431713 0.973838562224037 GO:0005537 D-mannose binding 1/1476 25/18639 0.04 0.505121951219512 0.873041096431713 0.973838562224037 GO:0015271 outward rectifier potassium channel activity 1/1476 25/18639 0.04 0.505121951219512 0.873041096431713 0.973838562224037 GO:0015662 P-type ion transporter activity 1/1476 25/18639 0.04 0.505121951219512 0.873041096431713 0.973838562224037 GO:0047617 fatty acyl-CoA hydrolase activity 1/1476 25/18639 0.04 0.505121951219512 0.873041096431713 0.973838562224037 GO:0140358 P-type transmembrane transporter activity 1/1476 25/18639 0.04 0.505121951219512 0.873041096431713 0.973838562224037 GO:0016790 thiolester hydrolase activity 2/1476 44/18639 0.0454545454545455 0.5740022172949 0.873451679598299 0.973838562224037 GO:0015078 proton transmembrane transporter activity 11/1476 185/18639 0.0594594594594595 0.750856954515491 0.875029554330875 0.97407963631792 GO:0004867 serine-type endopeptidase inhibitor activity 5/1476 95/18639 0.0526315789473684 0.664634146341463 0.880513047329833 0.97407963631792 GO:0140098 catalytic activity, acting on RNA 25/1476 387/18639 0.0645994832041344 0.815765425096111 0.881131152178668 0.97407963631792 GO:0051539 4 iron, 4 sulfur cluster binding 2/1476 45/18639 0.0444444444444444 0.561246612466125 0.881395667521947 0.97407963631792 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0005112 Notch binding 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0005227 calcium-activated cation channel activity 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0015145 monosaccharide transmembrane transporter activity 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0016289 acyl-CoA hydrolase activity 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0030247 polysaccharide binding 1/1476 26/18639 0.0384615384615385 0.485694183864916 0.883108322265322 0.97407963631792 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1476 63/18639 0.0476190476190476 0.601335656213705 0.885040729397622 0.974317388813095 GO:0022835 transmitter-gated channel activity 3/1476 63/18639 0.0476190476190476 0.601335656213705 0.885040729397622 0.974317388813095 GO:0000049 tRNA binding 4/1476 80/18639 0.05 0.63140243902439 0.886921566952741 0.975441839623412 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1476 46/18639 0.0434782608695652 0.549045599151644 0.888876145457619 0.976645135618971 GO:0004536 DNA nuclease activity 3/1476 64/18639 0.046875 0.591939786585366 0.891363134952297 0.977116917263769 GO:0005044 scavenger receptor activity 1/1476 27/18639 0.037037037037037 0.467705510388437 0.892377763856489 0.977116917263769 GO:0015252 proton channel activity 1/1476 27/18639 0.037037037037037 0.467705510388437 0.892377763856489 0.977116917263769 GO:0003735 structural constituent of ribosome 10/1476 175/18639 0.0571428571428571 0.721602787456446 0.894593096311514 0.977116917263769 GO:0019843 rRNA binding 3/1476 65/18639 0.0461538461538462 0.582833020637899 0.89737194831308 0.977116917263769 GO:0038024 cargo receptor activity 3/1476 65/18639 0.0461538461538462 0.582833020637899 0.89737194831308 0.977116917263769 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/1476 130/18639 0.0538461538461538 0.679971857410882 0.897864058895932 0.977116917263769 GO:0016866 intramolecular transferase activity 1/1476 28/18639 0.0357142857142857 0.451001742160279 0.900912602699591 0.977116917263769 GO:0046875 ephrin receptor binding 1/1476 28/18639 0.0357142857142857 0.451001742160279 0.900912602699591 0.977116917263769 GO:0050698 proteoglycan sulfotransferase activity 1/1476 28/18639 0.0357142857142857 0.451001742160279 0.900912602699591 0.977116917263769 GO:0051019 mitogen-activated protein kinase binding 1/1476 28/18639 0.0357142857142857 0.451001742160279 0.900912602699591 0.977116917263769 GO:0051119 sugar transmembrane transporter activity 1/1476 28/18639 0.0357142857142857 0.451001742160279 0.900912602699591 0.977116917263769 GO:0051959 dynein light intermediate chain binding 1/1476 28/18639 0.0357142857142857 0.451001742160279 0.900912602699591 0.977116917263769 GO:0031072 heat shock protein binding 7/1476 131/18639 0.0534351145038168 0.67478123254515 0.902057202888221 0.977116917263769 GO:0038187 pattern recognition receptor activity 2/1476 48/18639 0.0416666666666667 0.526168699186992 0.902539887306989 0.977116917263769 GO:0008235 metalloexopeptidase activity 3/1476 66/18639 0.0454545454545455 0.5740022172949 0.903079864501933 0.977116917263769 GO:0035254 glutamate receptor binding 2/1476 49/18639 0.0408163265306122 0.51543056246889 0.908767746768176 0.980470634350165 GO:0005416 amino acid:monoatomic cation symporter activity 1/1476 29/18639 0.0344827586206897 0.435449957947855 0.908771019679624 0.980470634350165 GO:0099604 ligand-gated calcium channel activity 1/1476 29/18639 0.0344827586206897 0.435449957947855 0.908771019679624 0.980470634350165 GO:0015081 sodium ion transmembrane transporter activity 9/1476 164/18639 0.0548780487804878 0.693002676977989 0.909845787393886 0.980697975965869 GO:0015171 amino acid transmembrane transporter activity 5/1476 102/18639 0.0490196078431373 0.61902199904352 0.914304537237366 0.982672476690552 GO:0019842 vitamin binding 8/1476 150/18639 0.0533333333333333 0.67349593495935 0.91491654973988 0.982672476690552 GO:0022839 monoatomic ion-gated channel activity 1/1476 30/18639 0.0333333333333333 0.420934959349593 0.9160065906067 0.982672476690552 GO:0048019 receptor antagonist activity 1/1476 30/18639 0.0333333333333333 0.420934959349593 0.9160065906067 0.982672476690552 GO:0098918 structural constituent of synapse 1/1476 30/18639 0.0333333333333333 0.420934959349593 0.9160065906067 0.982672476690552 GO:0030544 Hsp70 protein binding 2/1476 51/18639 0.0392156862745098 0.495217599234816 0.920120608725887 0.98609126016932 GO:0046906 tetrapyrrole binding 8/1476 152/18639 0.0526315789473684 0.664634146341463 0.921621008519807 0.98609126016932 GO:0047499 calcium-independent phospholipase A2 activity 1/1476 31/18639 0.032258064516129 0.4073564122738 0.922668650484421 0.98609126016932 GO:0072349 modified amino acid transmembrane transporter activity 1/1476 31/18639 0.032258064516129 0.4073564122738 0.922668650484421 0.98609126016932 GO:0008237 metallopeptidase activity 10/1476 184/18639 0.0543478260869565 0.686306998939555 0.924559345265389 0.98663675873394 GO:0005216 monoatomic ion channel activity 28/1476 448/18639 0.0625 0.789253048780488 0.925082351084213 0.98663675873394 GO:0047498 calcium-dependent phospholipase A2 activity 1/1476 32/18639 0.03125 0.394626524390244 0.92880262898211 0.98663675873394 GO:0071813 lipoprotein particle binding 1/1476 32/18639 0.03125 0.394626524390244 0.92880262898211 0.98663675873394 GO:0071814 protein-lipid complex binding 1/1476 32/18639 0.03125 0.394626524390244 0.92880262898211 0.98663675873394 GO:0015276 ligand-gated monoatomic ion channel activity 10/1476 186/18639 0.0537634408602151 0.678927353789667 0.930128286121638 0.98663675873394 GO:0016860 intramolecular oxidoreductase activity 2/1476 53/18639 0.0377358490566038 0.476530142659917 0.930133332022305 0.98663675873394 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1476 53/18639 0.0377358490566038 0.476530142659917 0.930133332022305 0.98663675873394 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/1476 33/18639 0.0303030303030303 0.382668144863267 0.934450359385851 0.986919896239897 GO:0019956 chemokine binding 1/1476 33/18639 0.0303030303030303 0.382668144863267 0.934450359385851 0.986919896239897 GO:0042923 neuropeptide binding 1/1476 33/18639 0.0303030303030303 0.382668144863267 0.934450359385851 0.986919896239897 GO:0022834 ligand-gated channel activity 10/1476 188/18639 0.0531914893617021 0.671704722366373 0.935339681566617 0.986919896239897 GO:0004521 RNA endonuclease activity 3/1476 73/18639 0.0410958904109589 0.51896090878717 0.935617452294387 0.986919896239897 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1476 73/18639 0.0410958904109589 0.51896090878717 0.935617452294387 0.986919896239897 GO:0030246 carbohydrate binding 16/1476 280/18639 0.0571428571428571 0.721602787456446 0.937347983218056 0.987827261794331 GO:0020037 heme binding 7/1476 142/18639 0.0492957746478873 0.622509446925455 0.939262312053152 0.988193992854269 GO:0003823 antigen binding 9/1476 174/18639 0.0517241379310345 0.653174936921783 0.939437284836789 0.988193992854269 GO:0004222 metalloendopeptidase activity 5/1476 110/18639 0.0454545454545455 0.5740022172949 0.942373827465755 0.988302607421142 GO:0044183 protein folding chaperone 3/1476 75/18639 0.04 0.505121951219512 0.942863313143438 0.988302607421142 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1476 56/18639 0.0357142857142857 0.451001742160279 0.942952630284745 0.988302607421142 GO:0004519 endonuclease activity 6/1476 127/18639 0.047244094488189 0.596600729786825 0.943023545230922 0.988302607421142 GO:0004623 phospholipase A2 activity 1/1476 35/18639 0.0285714285714286 0.360801393728223 0.944438111794997 0.988872008198636 GO:0004175 endopeptidase activity 24/1476 405/18639 0.0592592592592593 0.7483288166215 0.949509517195729 0.993265716144841 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/1476 130/18639 0.0461538461538462 0.582833020637899 0.950660590972983 0.993401980955365 GO:0019213 deacetylase activity 1/1476 37/18639 0.027027027027027 0.34129861568886 0.952904909975699 0.993401980955365 GO:0016758 hexosyltransferase activity 10/1476 197/18639 0.050761421319797 0.64101770459329 0.954829907842427 0.993401980955365 GO:0015370 solute:sodium symporter activity 3/1476 79/18639 0.0379746835443038 0.479546156221056 0.955137960754396 0.993401980955365 GO:0005179 hormone activity 6/1476 132/18639 0.0454545454545455 0.5740022172949 0.955226445280956 0.993401980955365 GO:0000146 microfilament motor activity 1/1476 38/18639 0.0263157894736842 0.332317073170732 0.956641731439836 0.993401980955365 GO:0005501 retinoid binding 1/1476 38/18639 0.0263157894736842 0.332317073170732 0.956641731439836 0.993401980955365 GO:0019840 isoprenoid binding 1/1476 38/18639 0.0263157894736842 0.332317073170732 0.956641731439836 0.993401980955365 GO:0009055 electron transfer activity 5/1476 116/18639 0.0431034482758621 0.544312447434819 0.957662705244938 0.993553172260517 GO:0033218 amide binding 13/1476 247/18639 0.0526315789473684 0.664634146341463 0.959732504419427 0.994245745057446 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/1476 39/18639 0.0256410256410256 0.32379612257661 0.960082234874856 0.994245745057446 GO:0008238 exopeptidase activity 4/1476 102/18639 0.0392156862745098 0.495217599234816 0.965554247148465 0.998324049935377 GO:0001530 lipopolysaccharide binding 1/1476 41/18639 0.024390243902439 0.308001189767995 0.966166357531417 0.998324049935377 GO:0051082 unfolded protein binding 5/1476 121/18639 0.0413223140495868 0.521820197540818 0.96746405432018 0.998324049935377 GO:0140375 immune receptor activity 7/1476 156/18639 0.0448717948717949 0.566643214509068 0.968242642318847 0.998324049935377 GO:0042056 chemoattractant activity 1/1476 42/18639 0.0238095238095238 0.300667828106852 0.968851509498491 0.998324049935377 GO:0160215 deacylase activity 2/1476 65/18639 0.0307692307692308 0.388555347091932 0.969297888131088 0.998324049935377 GO:0004497 monooxygenase activity 4/1476 106/18639 0.0377358490566038 0.476530142659917 0.972605158651779 0.999999958712008 GO:0008173 RNA methyltransferase activity 2/1476 67/18639 0.0298507462686567 0.376956680014561 0.97330159773991 0.999999958712008 GO:0030547 signaling receptor inhibitor activity 1/1476 44/18639 0.0227272727272727 0.28700110864745 0.973599784981513 0.999999958712008 GO:0140223 general transcription initiation factor activity 2/1476 68/18639 0.0294117647058824 0.371413199426112 0.975109450154156 0.999999958712008 GO:0008194 UDP-glycosyltransferase activity 6/1476 145/18639 0.0413793103448276 0.522539949537426 0.97667988014474 0.999999958712008 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1476 69/18639 0.0289855072463768 0.366030399434429 0.976798652614253 0.999999958712008 GO:0005261 monoatomic cation channel activity 18/1476 341/18639 0.0527859237536657 0.6665832200844 0.977992871981085 0.999999958712008 GO:0052689 carboxylic ester hydrolase activity 3/1476 92/18639 0.0326086956521739 0.411784199363733 0.98005980142664 0.999999958712008 GO:0022836 gated channel activity 16/1476 318/18639 0.050314465408805 0.635373523546556 0.983747844369337 0.999999958712008 GO:0030594 neurotransmitter receptor activity 3/1476 97/18639 0.0309278350515464 0.390558209705808 0.985529791526079 0.999999958712008 GO:0099094 ligand-gated monoatomic cation channel activity 5/1476 136/18639 0.0367647058823529 0.46426649928264 0.985685524492238 0.999999958712008 GO:0005249 voltage-gated potassium channel activity 3/1476 98/18639 0.0306122448979592 0.386572921851667 0.98643568397557 0.999999958712008 GO:0022853 active monoatomic ion transmembrane transporter activity 4/1476 118/18639 0.0338983050847458 0.428069450186027 0.986483770444332 0.999999958712008 GO:0008146 sulfotransferase activity 1/1476 53/18639 0.0188679245283019 0.238265071329959 0.987460655599845 0.999999958712008 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1476 53/18639 0.0188679245283019 0.238265071329959 0.987460655599845 0.999999958712008 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/1476 54/18639 0.0185185185185185 0.233852755194219 0.988456462784534 0.999999958712008 GO:0016853 isomerase activity 7/1476 180/18639 0.0388888888888889 0.491090785907859 0.990438652157804 0.999999958712008 GO:0005244 voltage-gated monoatomic ion channel activity 6/1476 173/18639 0.0346820809248555 0.437967009727901 0.994854201698599 0.999999958712008 GO:0001664 G protein-coupled receptor binding 13/1476 297/18639 0.0437710437710438 0.552742875913608 0.994879040577779 0.999999958712008 GO:0022832 voltage-gated channel activity 6/1476 175/18639 0.0342857142857143 0.432961672473868 0.995402620461062 0.999999958712008 GO:0015079 potassium ion transmembrane transporter activity 5/1476 160/18639 0.03125 0.394626524390244 0.996451702258489 0.999999958712008 GO:0016782 transferase activity, transferring sulphur-containing groups 1/1476 70/18639 0.0142857142857143 0.180400696864111 0.996930343181685 0.999999958712008 GO:0022843 voltage-gated monoatomic cation channel activity 4/1476 143/18639 0.027972027972028 0.353232133719939 0.99712795998126 0.999999958712008 GO:0005267 potassium channel activity 3/1476 124/18639 0.0241935483870968 0.30551730920535 0.997600478781307 0.999999958712008 GO:0004252 serine-type endopeptidase activity 5/1476 176/18639 0.0284090909090909 0.358751385809313 0.998661339808293 0.999999958712008 GO:0017171 serine hydrolase activity 6/1476 198/18639 0.0303030303030303 0.382668144863267 0.998789256167553 0.999999958712008 GO:0008236 serine-type peptidase activity 5/1476 194/18639 0.0257731958762887 0.32546517475484 0.999568331628927 0.999999958712008 GO:0140101 catalytic activity, acting on a tRNA 2/1476 139/18639 0.0143884892086331 0.181698543604141 0.999869373985929 0.999999958712008 GO:0008528 G protein-coupled peptide receptor activity 1/1476 122/18639 0.00819672131147541 0.103508596561375 0.999958889283964 0.999999958712008 GO:0001653 peptide receptor activity 1/1476 128/18639 0.0078125 0.098656631097561 0.999975026968649 0.999999958712008 GO:0005125 cytokine activity 4/1476 234/18639 0.0170940170940171 0.21586408171774 0.999994098498893 0.999999958712008 GO:0045182 translation regulator activity 9/1476 356/18639 0.0252808988764045 0.319248424225815 0.999996422501226 0.999999958712008 GO:0030371 translation repressor activity 5/1476 329/18639 0.0151975683890578 0.191915634961821 0.999999958712008 0.999999958712008