category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/64	78/9376	9.39102564102564	FCGR1A/JAK2/HLA-DRA/TLR2/FCGR3A	6.1690987218529
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	5/64	93/9376	7.87634408602151	MAF/JAK2/HLA-DRA/RBPJ/NFATC2	5.52470433450882
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	4/64	66/9376	8.87878787878788	MAF/HLA-DRA/IL21R/TLR2	5.32489044428279
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	6/64	181/9376	4.85635359116022	FCGR1A/JAK2/HLA-DRA/MRC1/TLR2/FCGR3A	4.34304580660564
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	6/64	216/9376	4.06944444444444	CCL2/JAK2/GSK3B/NFATC2/TLR2/ATF6	3.78349406925786
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	5/64	155/9376	4.7258064516129	FCGR1A/HLA-DRA/MRC1/TLR2/FCGR3A	3.87749521017269
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/64	109/9376	5.37614678899083	JAK2/HLA-DRA/IL21R/NFATC2	3.8096904575249
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	4/64	115/9376	5.09565217391304	ITPR2/KCNQ3/JAK2/GNG2	3.66350835551997
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/64	196/9376	3.73724489795918	ITPR2/JAK2/GNG2/GSK3B/NFATC2	3.2105134343968
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/64	70/9376	6.27857142857143	DTNA/HLA-DRA/EIF4G3	3.67483665947185
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/64	138/9376	4.2463768115942	CCL2/GSK3B/SKAP2/NFATC2	3.18495744050054
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	5/64	214/9376	3.42289719626168	ITPR2/GNG2/NFATC2/TLR2/FBXW11	2.97235632906998
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/64	140/9376	4.18571428571429	ITPR2/MEF2A/MEF2C/GNG2	3.14835009921759
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	4/64	142/9376	4.12676056338028	ITPR2/FCGR1A/NFATC2/FCGR3A	3.11241861672384
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	4/64	143/9376	4.0979020979021	FCGR1A/HLA-DRA/C9/FCGR3A	3.09469911874415
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/64	227/9376	3.22687224669604	ITPR2/CCL2/GNG2/GSK3B/NFATC2	2.81562983915978
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	2/64	34/9376	8.61764705882353	PER3/FBXW11	3.68887989681906
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/64	90/9376	4.88333333333333	JAK2/NFATC2/TLR2	3.06877980314393
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/64	93/9376	4.7258064516129	FER/CTNND1/PTPRJ	2.99344808742347
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	4/64	166/9376	3.53012048192771	ITPR2/MEF2A/MEF2C/NFATC2	2.72658833786079
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/64	95/9376	4.62631578947368	CCL2/HLA-DRA/TLR2	2.94499240298687
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/64	98/9376	4.48469387755102	FCGR1A/PTPRC/FCGR3A	2.87478008495263
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/64	99/9376	4.43939393939394	FCGR1A/HLA-DRA/FCGR3A	2.85200237074629
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	4/64	178/9376	3.29213483146067	TLE4/GSK3B/NFATC2/FBXW11	2.559514539041
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	4/64	180/9376	3.25555555555556	CCL2/JAK2/HLA-DRA/TLR2	2.53305395932364
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/64	112/9376	3.92410714285714	JAK2/HLA-DRA/TLR2	2.5808167062076
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/64	193/9376	3.03626943005181	CCL2/JAK2/GNG2/GSK3B	2.36960384158013
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/64	115/9376	3.82173913043478	ITPR2/MEF2A/MEF2C	2.52400947211514
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	4/64	195/9376	3.00512820512821	HDAC9/FCGR1A/TLR2/FCGR3A	2.34567910677598
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	2/64	49/9376	5.97959183673469	ST6GAL1/GALNT1	2.89717640428224
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/64	50/9376	5.86	CCL2/TLR2	2.85645710961314
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	2/64	51/9376	5.74509803921569	ENPP2/LPCAT2	2.8168258605774
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/64	201/9376	2.91542288557214	BMP2K/MAF/FCGR1A/MEF2C	2.27569369296845
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/64	122/9376	3.60245901639344	GSK3B/PTPRC/NFATC2	2.39857447790611
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/64	122/9376	3.60245901639344	ITPR2/JAK2/GSK3B	2.39857447790611
NA	NA	hsa04517	IgSF CAM signaling	5/64	299/9376	2.44983277591973	KCNQ3/UNC5C/MTSS1/EPB41L2/GSK3B	2.11220701894781
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	2/64	56/9376	5.23214285714286	GSK3B/FBXW11	2.63330108372001
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/64	133/9376	3.30451127819549	ITPR2/GNG2/GSK3B	2.21897456107731
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	2/64	62/9376	4.7258064516129	TLE4/RBPJ	2.44006929463303
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/64	142/9376	3.09507042253521	WWP1/PIAS2/FBXW11	2.08546067224176
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/64	142/9376	3.09507042253521	MEF2A/CCL2/MEF2C	2.08546067224176
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	4/64	238/9376	2.46218487394958	CCL2/C9/TLR2/F13A1	1.89417164059236
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/64	71/9376	4.12676056338028	JAK2/GSK3B	2.19239979553055
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/64	154/9376	2.8538961038961	ITPR2/MEF2C/NFATC2	1.92303564700604
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/64	157/9376	2.79936305732484	JAK2/MERTK/NFATC2	1.88486764697137
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/64	157/9376	2.79936305732484	ITPR2/NFATC2/FBXW11	1.88486764697137
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/64	163/9376	2.69631901840491	JAK2/NFATC2/TLR2	1.81115216519393
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/64	79/9376	3.70886075949367	SYT1/NSF	2.00439335255976
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/64	80/9376	3.6625	JAK2/GSK3B	1.98262552876335
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/64	168/9376	2.61607142857143	JAK2/IL21R/PIAS2	1.75221211709172
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/64	173/9376	2.54046242774566	CCL2/JAK2/HLA-DRA	1.69536648033882
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/64	88/9376	3.32954545454545	C9/F13A1	1.82014322368334
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/64	89/9376	3.29213483146067	GNG2/NSF	1.80115705226405
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/64	91/9376	3.21978021978022	GSK3B/NFATC2	1.76398082856112
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/64	184/9376	2.38858695652174	UNC5C/GSK3B/NFATC2	1.57699794234373
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/64	21/9376	6.97619047619048	CHSY3	2.27282670762908
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/64	94/9376	3.11702127659574	CCL2/GSK3B	1.71010394600146
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/64	187/9376	2.35026737967914	ITPR2/CCL2/IFI16	1.5461819354597
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/64	97/9376	3.02061855670103	GNG2/PER3	1.65834069547627
Metabolism	Glycan biosynthesis and metabolism	hsa00515	Mannose type O-glycan biosynthesis	1/64	23/9376	6.3695652173913	LARGE1	2.13737986555397
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/64	100/9376	2.93	FCGR1A/HLA-DRA	1.60853709427095
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/64	101/9376	2.9009900990099	CCL2/JAK2	1.59234703740015
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/64	102/9376	2.87254901960784	ITPR2/SLC26A3	1.57635445011287
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/64	103/9376	2.84466019417476	CCL2/TLR2	1.56055471525763
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/64	103/9376	2.84466019417476	C9/TLR2	1.56055471525763
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/64	104/9376	2.81730769230769	LPCAT2/ETNK1	1.54494336866584
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/64	105/9376	2.79047619047619	ITPR2/NFATC2	1.52951609264612
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/64	205/9376	2.14390243902439	HLA-DRA/RBPJ/TLR2	1.37281403750038
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/64	205/9376	2.14390243902439	HDAC9/RBPJ/RASA2	1.37281403750038
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/64	109/9376	2.68807339449541	GSK3B/TBC1D4	1.469566130366
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/64	115/9376	2.54782608695652	ITPR2/GNG2	1.38451058871031
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/64	116/9376	2.52586206896552	ARHGAP5/CTNND1	1.37085941764831
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/64	116/9376	2.52586206896552	ITPR2/GNG2	1.37085941764831
Human Diseases	Immune disease	hsa05310	Asthma	1/64	32/9376	4.578125	HLA-DRA	1.68080845549628
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/64	122/9376	2.4016393442623	GSK3B/TBC1D4	1.29183066369116
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/64	36/9376	4.06944444444444	GALNT1	1.52964880253932
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/64	38/9376	3.85526315789474	PTPRC	1.46205983523791
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/64	133/9376	2.20300751879699	NFATC2/FCGR3A	1.15835539893106
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/64	362/9376	1.61878453038674	JAK2/GNG2/GSK3B/TLR2	0.995380429621115
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/64	39/9376	3.75641025641026	HLA-DRA	1.42996900094278
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/64	136/9376	2.15441176470588	GSK3B/TLR2	1.12421235580172
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/64	248/9376	1.77217741935484	EXOC4/PTPRC/TLR2	1.02166675980254
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/64	138/9376	2.1231884057971	ITPR2/FBXW11	1.10193840017318
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/64	253/9376	1.73715415019763	ITPR2/GSK3B/FBXW11	0.985380309473928
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/64	144/9376	2.03472222222222	JAK2/GSK3B	1.03731645216634
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/64	144/9376	2.03472222222222	ITPR2/RBPJ	1.03731645216634
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/64	44/9376	3.32954545454545	HLA-DRA	1.28399787099422
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/64	44/9376	3.32954545454545	NSF	1.28399787099422
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/64	45/9376	3.25555555555556	HLA-DRA	1.25733160448874
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/64	149/9376	1.96644295302013	ITPR2/GNG2	0.985810044996697
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/64	155/9376	1.89032258064516	ITPR2/GSK3B	0.926570283989319
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	3/64	275/9376	1.59818181818182	ITPR2/GSK3B/C9	0.834659113491056
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/64	50/9376	2.93	HLA-DRA	1.13435436657477
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/64	157/9376	1.86624203821656	GSK3B/FBXW11	0.907405309692411
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/64	160/9376	1.83125	HLA-DRA/PTPRC	0.879173437257626
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/64	54/9376	2.71296296296296	HLA-DRA	1.04651256014693
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/64	56/9376	2.61607142857143	ST6GAL1	1.00554324082979
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/64	56/9376	2.61607142857143	TLR2	1.00554324082979
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/64	298/9376	1.4748322147651	CCL2/IL21R/EDA	0.690569447469819
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/64	59/9376	2.48305084745763	GSK3B	0.947323129464126
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/64	300/9376	1.465	MEF2C/MAP4K4/RASA2	0.678610348545001
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/64	60/9376	2.44166666666667	NFATC2	0.928709491026655
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/64	60/9376	2.44166666666667	ITPR2	0.928709491026655
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/64	61/9376	2.4016393442623	SLC26A3	0.910466370635461
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/64	63/9376	2.32539682539683	GSK3B	0.875035234455376
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/64	65/9376	2.25384615384615	ITPR2	0.840924312125603
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/64	65/9376	2.25384615384615	ITPR2	0.840924312125603
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/64	67/9376	2.1865671641791	ITPR2	0.80803905803274
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/64	68/9376	2.15441176470588	FCGR1A	0.792029129717887
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/64	191/9376	1.53403141361257	HDAC9/GNG2	0.618155943589705
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/64	69/9376	2.1231884057971	ITPR2	0.77629437933808
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/64	70/9376	2.09285714285714	JAK2	0.760825451825701
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/64	75/9376	1.95333333333333	SESN3	0.687170851818105
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/64	75/9376	1.95333333333333	ITPR2	0.687170851818105
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/64	203/9376	1.44334975369458	ARHGAP5/GSK3B	0.529410968941342
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/64	76/9376	1.92763157894737	ITPR2	0.673123864633885
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/64	204/9376	1.43627450980392	ITPR2/TLR2	0.522272358774099
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/64	205/9376	1.42926829268293	GSK3B/TBC1D4	0.515171152665388
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/64	82/9376	1.78658536585366	HLA-DRA	0.593069508088287
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/64	83/9376	1.76506024096386	SFMBT2	0.580377880395076
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/64	83/9376	1.76506024096386	IFI16	0.580377880395076
NA	NA	hsa04081	Hormone signaling	2/64	219/9376	1.337899543379	JAK2/GNG2	0.419456758881081
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/64	86/9376	1.70348837209302	GSK3B	0.543315923565461
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/64	86/9376	1.70348837209302	SCN9A	0.543315923565461
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/64	86/9376	1.70348837209302	DTNA	0.543315923565461
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/64	87/9376	1.68390804597701	GSK3B	0.531284321127001
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/64	224/9376	1.30803571428571	HLA-DRA/NFATC2	0.386830952733215
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/64	89/9376	1.64606741573034	ITPR2	0.507679071103838
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/64	90/9376	1.62777777777778	SESN3	0.496097450293654
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/64	91/9376	1.60989010989011	GNG2	0.484658098936347
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/64	232/9376	1.26293103448276	C9/TMSB4X	0.336180001981194
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/64	93/9376	1.5752688172043	ITPR2	0.462191840338111
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/64	93/9376	1.5752688172043	ITPR2	0.462191840338111
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/64	238/9376	1.23109243697479	GNG2/RASA2	0.299366207564885
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/64	98/9376	1.49489795918367	ITPR2	0.408277698741442
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/64	98/9376	1.49489795918367	ITPR2	0.408277698741442
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/64	99/9376	1.47979797979798	ITPR2	0.39785642470029
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/64	99/9376	1.47979797979798	DTNA	0.39785642470029
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/64	388/9376	1.13273195876289	ITPR2/GSK3B/ATF6	0.221367558869671
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/64	100/9376	1.465	CCL2	0.387549092661136
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/64	101/9376	1.45049504950495	GSK3B	0.377353073967222
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/64	250/9376	1.172	WWP1/PSD3	0.228513762233693
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/64	105/9376	1.3952380952381	EDA	0.337632541727733
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/64	105/9376	1.3952380952381	DTNA	0.337632541727733
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/64	106/9376	1.38207547169811	GSK3B	0.327956592232637
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/64	254/9376	1.15354330708661	ITPR2/NFATC2	0.205663326634821
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/64	107/9376	1.36915887850467	ITPR2	0.318377895167132
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/64	109/9376	1.34403669724771	TLR2	0.299503966786549
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	2/64	268/9376	1.09328358208955	ITPR2/ATF6	0.128444420068327
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/64	119/9376	1.23109243697479	CCL2	0.210318861805334
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/64	120/9376	1.22083333333333	GSK3B	0.201835576508352
Organismal Systems	Immune system	hsa04611	Platelet activation	1/64	126/9376	1.16269841269841	ITPR2	0.152423476781477
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/64	130/9376	1.12692307692308	GNG2	0.120806267145719
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/64	134/9376	1.09328358208955	ITPR2	0.0901630871296143
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/64	137/9376	1.06934306569343	ITPR2	0.0677805330086855
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/64	138/9376	1.06159420289855	GSK3B	0.0604288800094968
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/64	139/9376	1.05395683453237	ITPR2	0.0531303323989724
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/64	144/9376	1.01736111111111	GSK3B	0.0174046384591668
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/64	148/9376	0.989864864864865	GSK3B	-0.0103029300192946
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	3/64	480/9376	0.915625	ITPR2/GSK3B/ATF6	-0.15732261585193
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/64	150/9376	0.976666666666667	GSK3B	-0.0238819525554171
NA	NA	hsa04518	Integrin signaling	1/64	154/9376	0.951298701298701	GSK3B	-0.0505175739143443
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/64	156/9376	0.939102564102564	GSK3B	-0.0635843135609881
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/64	157/9376	0.93312101910828	GSK3B	-0.0700570275865464
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/64	158/9376	0.927215189873418	GSK3B	-0.0764900749585073
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/64	158/9376	0.927215189873418	GSK3B	-0.0764900749585073
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/64	333/9376	0.87987987987988	RBPJ/GSK3B	-0.185027274112883
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/64	168/9376	0.872023809523809	JAK2	-0.138757128977797
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/64	169/9376	0.866863905325444	WDFY3	-0.14478855564113
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/64	170/9376	0.861764705882353	GSK3B	-0.150786360147396
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/64	174/9376	0.841954022988506	ATF6	-0.17445004939909
NA	NA	hsa04082	Neuroactive ligand signaling	1/64	199/9376	0.736180904522613	GNG2	-0.311843388522444
NA	NA	hsa04519	Cadherin signaling	2/64	404/9376	0.725247524752475	CTNND1/GSK3B	-0.467995638115122
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/64	212/9376	0.691037735849057	CTNND1	-0.377211540178587
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/64	217/9376	0.675115207373272	JAK2	-0.40141108564896
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/64	227/9376	0.645374449339207	PTPRJ	-0.448384178145129
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/64	233/9376	0.628755364806867	DTNA	-0.475716186315232
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/64	250/9376	0.586	AP3B1	-0.55002731142296
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/64	323/9376	0.453560371517028	ZEB2	-0.828516820587652
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/64	368/9376	0.398097826086956	ATF6	-0.976539408419339