ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030695 GTPase regulator activity 17/204 489/18639 0.0347648261758691 3.17638036809816 2.86113089582957e-05 0.0085722265088549 GO:0060589 nucleoside-triphosphatase regulator activity 17/204 490/18639 0.0346938775510204 3.16989795918367 2.93569400988181e-05 0.0085722265088549 GO:0005096 GTPase activator activity 12/204 271/18639 0.044280442804428 4.0457998697634 4.6080252588782e-05 0.00897028917061623 GO:0050321 tau-protein kinase activity 4/204 22/18639 0.181818181818182 16.6122994652406 8.73197558087226e-05 0.00898673107358442 GO:0004674 protein serine/threonine kinase activity 15/204 433/18639 0.0346420323325635 3.16516098356202 8.87989036632861e-05 0.00898673107358442 GO:0141003 histone H2AX kinase activity 13/204 354/18639 0.0367231638418079 3.35530907278166 0.00014887075351513 0.00898673107358442 GO:0004713 protein tyrosine kinase activity 8/204 140/18639 0.0571428571428571 5.22100840336134 0.000156033587171828 0.00898673107358442 GO:0140996 histone H3 kinase activity 13/204 357/18639 0.0364145658263305 3.32711319822046 0.000161757885024763 0.00898673107358442 GO:0008013 beta-catenin binding 7/204 106/18639 0.0660377358490566 6.03371254162042 0.000165632313302668 0.00898673107358442 GO:0035173 histone kinase activity 13/204 360/18639 0.0361111111111111 3.29938725490196 0.00017559414445378 0.00898673107358442 GO:0106310 protein serine kinase activity 13/204 361/18639 0.03601108033241 3.29024767801858 0.000180426912959545 0.00898673107358442 GO:0098631 cell adhesion mediator activity 6/204 76/18639 0.0789473684210526 7.21323529411765 0.000184658857676392 0.00898673107358442 GO:0030165 PDZ domain binding 6/204 83/18639 0.072289156626506 6.60489014883062 0.000299257664880805 0.0134435750992608 GO:0098632 cell-cell adhesion mediator activity 5/204 55/18639 0.0909090909090909 8.30614973262032 0.000333564232638343 0.0139143937043423 GO:0098641 cadherin binding involved in cell-cell adhesion 3/204 18/18639 0.166666666666667 15.2279411764706 0.00093378573844008 0.0363553914166004 GO:0048156 tau protein binding 4/204 43/18639 0.0930232558139535 8.49931600547196 0.00123119707729231 0.0449386933211695 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/204 45/18639 0.0888888888888889 8.12156862745098 0.00146136033677747 0.0502020256869437 GO:0017124 SH3 domain binding 6/204 115/18639 0.0521739130434783 4.76700767263427 0.0016719840443629 0.0542465934393298 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/204 24/18639 0.125 11.4209558823529 0.00220695256802374 0.0644430149862932 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/204 24/18639 0.125 11.4209558823529 0.00220695256802374 0.0644430149862932 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/204 26/18639 0.115384615384615 10.5424208144796 0.00278983861500773 0.0698910644210794 GO:0046875 ephrin receptor binding 3/204 28/18639 0.107142857142857 9.78939075630252 0.00345923690582775 0.0698910644210794 GO:0141052 histone H3 demethylase activity 3/204 28/18639 0.107142857142857 9.78939075630252 0.00345923690582775 0.0698910644210794 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/204 29/18639 0.103448275862069 9.45182555780933 0.00382756957780314 0.0698910644210794 GO:0097472 cyclin-dependent protein kinase activity 3/204 29/18639 0.103448275862069 9.45182555780933 0.00382756957780314 0.0698910644210794 GO:0032452 histone demethylase activity 3/204 30/18639 0.1 9.13676470588235 0.00421891323731207 0.0698910644210794 GO:0140457 protein demethylase activity 3/204 31/18639 0.0967741935483871 8.84203036053131 0.00463368109642633 0.0698910644210794 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 8/204 243/18639 0.0329218106995885 3.0079883805374 0.00541642381980317 0.0698910644210794 GO:0004676 3-phosphoinositide-dependent protein kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0004711 ribosomal protein S6 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0035175 histone H3S10 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0035979 histone H2AXS139 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0044022 histone H3S28 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0044023 histone H4S1 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0044024 histone H2AS1 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0044025 histone H2BS14 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0072354 histone H3T3 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0072371 histone H2AS121 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0072518 Rho-dependent protein serine/threonine kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0140823 histone H2BS36 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0140855 histone H3S57 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0140995 histone H2A kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0140997 histone H4 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0140998 histone H2B kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:1990244 histone H2AT120 kinase activity 8/204 245/18639 0.0326530612244898 2.98343337334934 0.00568376167193705 0.0698910644210794 GO:0004677 DNA-dependent protein kinase activity 8/204 246/18639 0.032520325203252 2.9713055954089 0.00582114793173849 0.0698910644210794 GO:0140857 histone H3T45 kinase activity 8/204 246/18639 0.032520325203252 2.9713055954089 0.00582114793173849 0.0698910644210794 GO:0035402 histone H3T11 kinase activity 8/204 247/18639 0.0323886639676113 2.95927601809955 0.00596105115836697 0.0698910644210794 GO:0035403 histone H3T6 kinase activity 8/204 247/18639 0.0323886639676113 2.95927601809955 0.00596105115836697 0.0698910644210794 GO:0030332 cyclin binding 3/204 34/18639 0.0882352941176471 8.06185121107266 0.00602233585613824 0.0698910644210794 GO:0004679 AMP-activated protein kinase activity 8/204 248/18639 0.032258064516129 2.94734345351044 0.00610350048882714 0.0698910644210794 GO:0061775 cohesin loader activity 6/204 153/18639 0.0392156862745098 3.58304498269896 0.00682264962528359 0.0766236034839541 GO:0097110 scaffold protein binding 4/204 70/18639 0.0571428571428571 5.22100840336134 0.00727709655584203 0.0791583139586688 GO:0034452 dynactin binding 2/204 12/18639 0.166666666666667 15.2279411764706 0.0073194331400139 0.0791583139586688 GO:0042805 actinin binding 3/204 37/18639 0.0810810810810811 7.40818759936407 0.00763463646849686 0.0810659581382212 GO:0005518 collagen binding 4/204 72/18639 0.0555555555555556 5.07598039215686 0.00802871635502072 0.0837280419880733 GO:0004535 poly(A)-specific ribonuclease activity 2/204 13/18639 0.153846153846154 14.0565610859729 0.00858828228321987 0.0846159413826124 GO:0070700 BMP receptor binding 2/204 13/18639 0.153846153846154 14.0565610859729 0.00858828228321987 0.0846159413826124 GO:0035401 histone H3Y41 kinase activity 5/204 115/18639 0.0434782608695652 3.97250639386189 0.00869341863519991 0.0846159413826124 GO:0140801 histone H2AXY142 kinase activity 5/204 115/18639 0.0434782608695652 3.97250639386189 0.00869341863519991 0.0846159413826124 GO:0003725 double-stranded RNA binding 4/204 75/18639 0.0533333333333333 4.87294117647059 0.00924885876404732 0.0885464511180924 GO:0032451 demethylase activity 3/204 40/18639 0.075 6.85257352941176 0.00947840726160394 0.08928048130285 GO:0032454 histone H3K9 demethylase activity 2/204 14/18639 0.142857142857143 13.0525210084034 0.00994796138764179 0.0922160230219493 GO:0005201 extracellular matrix structural constituent 6/204 168/18639 0.0357142857142857 3.26313025210084 0.010557561779472 0.0960875578522251 GO:0042056 chemoattractant activity 3/204 42/18639 0.0714285714285714 6.52626050420168 0.0108393670585846 0.0960875578522251 GO:0046332 SMAD binding 4/204 79/18639 0.0506329113924051 4.62620997766195 0.0110550551217413 0.0960875578522251 GO:0033130 acetylcholine receptor binding 2/204 15/18639 0.133333333333333 12.1823529411765 0.0113963502527763 0.0960875578522251 GO:0051371 muscle alpha-actinin binding 2/204 15/18639 0.133333333333333 12.1823529411765 0.0113963502527763 0.0960875578522251 GO:0120283 protein serine/threonine kinase binding 2/204 15/18639 0.133333333333333 12.1823529411765 0.0113963502527763 0.0960875578522251 GO:0045296 cadherin binding 9/204 334/18639 0.0269461077844311 2.46200246565692 0.0115173442631092 0.0960875578522251 GO:0005085 guanyl-nucleotide exchange factor activity 7/204 230/18639 0.0304347826086957 2.78075447570332 0.0135376597992315 0.111352018630299 GO:0046965 nuclear retinoid X receptor binding 2/204 17/18639 0.117647058823529 10.7491349480969 0.0145509516184244 0.118024385349443 GO:0017075 syntaxin-1 binding 2/204 18/18639 0.111111111111111 10.1519607843137 0.0162530973534225 0.13002477882738 GO:0001664 G protein-coupled receptor binding 8/204 297/18639 0.0269360269360269 2.46108140225787 0.0168155545631605 0.132706538714672 GO:0005539 glycosaminoglycan binding 7/204 242/18639 0.0289256198347107 2.64286582401556 0.0174274575220929 0.13570180257203 GO:0070851 growth factor receptor binding 5/204 139/18639 0.0359712230215827 3.2866060093102 0.0184950446575123 0.142119816841936 GO:0140297 DNA-binding transcription factor binding 11/204 488/18639 0.0225409836065574 2.05951663452266 0.0188851020342782 0.143043837802768 GO:0051213 dioxygenase activity 4/204 93/18639 0.043010752688172 3.92979127134725 0.019105170117493 0.143043837802768 GO:0003712 transcription coregulator activity 11/204 495/18639 0.0222222222222222 2.03039215686274 0.0207270200773474 0.15322252816672 GO:0140463 chromatin-protein adaptor activity 3/204 54/18639 0.0555555555555556 5.07598039215686 0.0212935447747138 0.155442876855411 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/204 21/18639 0.0952380952380952 8.70168067226891 0.0218352203805143 0.157429243237288 GO:0008093 cytoskeletal anchor activity 2/204 22/18639 0.0909090909090909 8.30614973262032 0.0238480998513206 0.1651404133031 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/204 22/18639 0.0909090909090909 8.30614973262032 0.0238480998513206 0.1651404133031 GO:0031683 G-protein beta/gamma-subunit complex binding 2/204 22/18639 0.0909090909090909 8.30614973262032 0.0238480998513206 0.1651404133031 GO:0000510 H3-H4 histone complex chaperone activity 5/204 151/18639 0.033112582781457 3.02541877678224 0.0253770645180076 0.1651404133031 GO:0140584 chromatin extrusion motor activity 5/204 151/18639 0.033112582781457 3.02541877678224 0.0253770645180076 0.1651404133031 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/204 151/18639 0.033112582781457 3.02541877678224 0.0253770645180076 0.1651404133031 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/204 151/18639 0.033112582781457 3.02541877678224 0.0253770645180076 0.1651404133031 GO:0005158 insulin receptor binding 2/204 23/18639 0.0869565217391304 7.94501278772378 0.0259339503668704 0.1651404133031 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/204 23/18639 0.0869565217391304 7.94501278772378 0.0259339503668704 0.1651404133031 GO:0015616 DNA translocase activity 5/204 152/18639 0.0328947368421053 3.00551470588235 0.0260152705888445 0.1651404133031 GO:0140674 ATP-dependent histone chaperone activity 5/204 152/18639 0.0328947368421053 3.00551470588235 0.0260152705888445 0.1651404133031 GO:0004879 nuclear receptor activity 3/204 59/18639 0.0508474576271186 4.64581256231306 0.0268280979615277 0.166676693718427 GO:0070888 E-box binding 3/204 59/18639 0.0508474576271186 4.64581256231306 0.0268280979615277 0.166676693718427 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/204 60/18639 0.05 4.56838235294118 0.028018458173475 0.167399131606031 GO:0098531 ligand-modulated transcription factor activity 3/204 60/18639 0.05 4.56838235294118 0.028018458173475 0.167399131606031 GO:0035035 histone acetyltransferase binding 2/204 24/18639 0.0833333333333333 7.61397058823529 0.0280909501667655 0.167399131606031 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/204 24/18639 0.0833333333333333 7.61397058823529 0.0280909501667655 0.167399131606031 GO:0015026 coreceptor activity 3/204 61/18639 0.0491803278688525 4.49349083895853 0.029236543106696 0.172466072467783 GO:0140658 ATP-dependent chromatin remodeler activity 5/204 158/18639 0.0316455696202532 2.89138123603872 0.0300601302721669 0.175300079575547 GO:0042974 nuclear retinoic acid receptor binding 2/204 25/18639 0.08 7.30941176470588 0.0303173082827572 0.175300079575547 GO:0003689 DNA clamp loader activity 5/204 160/18639 0.03125 2.85523897058824 0.0314915736195235 0.179669605921013 GO:0140097 catalytic activity, acting on DNA 8/204 336/18639 0.0238095238095238 2.17542016806723 0.0320171881483484 0.179669605921013 GO:0005178 integrin binding 5/204 161/18639 0.031055900621118 2.83750456704421 0.0322230618256312 0.179669605921013 GO:0008143 poly(A) binding 2/204 26/18639 0.0769230769230769 7.02828054298643 0.032611264088403 0.179669605921013 GO:0050750 low-density lipoprotein particle receptor binding 2/204 26/18639 0.0769230769230769 7.02828054298643 0.032611264088403 0.179669605921013 GO:0140713 histone chaperone activity 5/204 164/18639 0.0304878048780488 2.78559899569584 0.0344810081265434 0.188195408840199 GO:0008266 poly(U) RNA binding 2/204 27/18639 0.0740740740740741 6.76797385620915 0.0349710868548165 0.189102914103822 GO:0050840 extracellular matrix binding 3/204 67/18639 0.0447761194029851 4.09108867427568 0.0371233146915987 0.196745261103241 GO:0035091 phosphatidylinositol binding 7/204 284/18639 0.0246478873239437 2.25201946975973 0.037155823125193 0.196745261103241 GO:0051393 alpha-actinin binding 2/204 28/18639 0.0714285714285714 6.52626050420168 0.037395075312431 0.196745261103241 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 8/204 349/18639 0.0229226361031519 2.09438732513063 0.0386887884637153 0.201734396989373 GO:1990782 protein tyrosine kinase binding 4/204 117/18639 0.0341880341880342 3.1236802413273 0.0397360793547381 0.204305521190532 GO:0099604 ligand-gated calcium channel activity 2/204 29/18639 0.0689655172413793 6.30121703853955 0.0398815572186997 0.204305521190532 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/204 484/18639 0.0206611570247934 1.88776130286825 0.0408436554249962 0.206277686667817 GO:0008201 heparin binding 5/204 172/18639 0.0290697674418605 2.65603625170999 0.0409729651600458 0.206277686667817 GO:0001968 fibronectin binding 2/204 30/18639 0.0666666666666667 6.09117647058823 0.042428888931656 0.206487259467393 GO:0008187 poly-pyrimidine tract binding 2/204 30/18639 0.0666666666666667 6.09117647058823 0.042428888931656 0.206487259467393 GO:0031624 ubiquitin conjugating enzyme binding 2/204 30/18639 0.0666666666666667 6.09117647058823 0.042428888931656 0.206487259467393 GO:0033612 receptor serine/threonine kinase binding 2/204 30/18639 0.0666666666666667 6.09117647058823 0.042428888931656 0.206487259467393 GO:0001216 DNA-binding transcription activator activity 10/204 491/18639 0.0203665987780041 1.86084820893734 0.0442712287405539 0.213672707309781 GO:0070325 lipoprotein particle receptor binding 2/204 31/18639 0.0645161290322581 5.89468690702087 0.045035454989258 0.215579555030547 GO:0042578 phosphoric ester hydrolase activity 8/204 363/18639 0.0220385674931129 2.01361205639281 0.0468535968794439 0.222459354289392 GO:0070717 poly-purine tract binding 2/204 32/18639 0.0625 5.71047794117647 0.0476996676944439 0.224650047851252 GO:0030296 protein tyrosine kinase activator activity 2/204 33/18639 0.0606060606060606 5.53743315508021 0.0504199667058222 0.23487016109013 GO:0046982 protein heterodimerization activity 8/204 369/18639 0.021680216802168 1.98087039693926 0.0506740416050624 0.23487016109013 GO:0031490 chromatin DNA binding 4/204 128/18639 0.03125 2.85523897058824 0.0522162120674247 0.240112345254929 GO:0019199 transmembrane receptor protein kinase activity 3/204 78/18639 0.0384615384615385 3.51414027149321 0.0540952919410305 0.246809769480952 GO:0003779 actin binding 9/204 443/18639 0.0203160270880361 1.85622759261718 0.0553959149776656 0.249852722346828 GO:0000175 3'-5'-RNA exonuclease activity 2/204 35/18639 0.0571428571428571 5.22100840336134 0.0560227166429659 0.249852722346828 GO:0140597 protein carrier chaperone 5/204 188/18639 0.0265957446808511 2.42999061326658 0.0560457305264288 0.249852722346828 GO:0140104 molecular carrier activity 6/204 249/18639 0.0240963855421687 2.20163004961021 0.0565067040610956 0.249999357361211 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/204 36/18639 0.0555555555555556 5.07598039215686 0.0589021800579833 0.258301121885167 GO:0030971 receptor tyrosine kinase binding 3/204 81/18639 0.037037037037037 3.38398692810457 0.0592677231722814 0.258301121885167 GO:0002020 protease binding 4/204 136/18639 0.0294117647058824 2.68728373702422 0.0624861842221528 0.268323026365715 GO:0140789 histone phosphatase activity 4/204 136/18639 0.0294117647058824 2.68728373702422 0.0624861842221528 0.268323026365715 GO:0016922 nuclear receptor binding 4/204 137/18639 0.0291970802919708 2.66766852726492 0.063839649928265 0.272133982175962 GO:0004527 exonuclease activity 3/204 84/18639 0.0357142857142857 3.26313025210084 0.0646638614424412 0.272295289152393 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/204 38/18639 0.0526315789473684 4.80882352941176 0.0648100088907236 0.272295289152393 GO:0008081 phosphoric diester hydrolase activity 3/204 87/18639 0.0344827586206897 3.15060851926978 0.0702781071605898 0.291617390987216 GO:0004532 RNA exonuclease activity 2/204 40/18639 0.05 4.56838235294118 0.0709069683564805 0.291617390987216 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/204 40/18639 0.05 4.56838235294118 0.0709069683564805 0.291617390987216 GO:0019955 cytokine binding 4/204 144/18639 0.0277777777777778 2.53799019607843 0.0737404890619522 0.294539374670641 GO:0042169 SH2 domain binding 2/204 41/18639 0.0487804878048781 4.45695839311334 0.0740229374765806 0.294539374670641 GO:0003727 single-stranded RNA binding 3/204 89/18639 0.0337078651685393 3.07980832782551 0.0741391919119592 0.294539374670641 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/204 89/18639 0.0337078651685393 3.07980832782551 0.0741391919119592 0.294539374670641 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/204 89/18639 0.0337078651685393 3.07980832782551 0.0741391919119592 0.294539374670641 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/204 268/18639 0.0223880597014925 2.04554433713784 0.0747969319319093 0.295144650325912 GO:0140793 histone H2AXY142 phosphatase activity 3/204 90/18639 0.0333333333333333 3.04558823529412 0.0761045293158637 0.298288893425936 GO:0016791 phosphatase activity 6/204 273/18639 0.021978021978022 2.00808015513898 0.0801113172223476 0.311900061719007 GO:0008094 ATP-dependent activity, acting on DNA 5/204 210/18639 0.0238095238095238 2.17542016806723 0.0813408279011033 0.314589692014863 GO:1901681 sulfur compound binding 6/204 275/18639 0.0218181818181818 1.99347593582888 0.0822951375992208 0.316186581302269 GO:0001217 DNA-binding transcription repressor activity 6/204 278/18639 0.0215827338129496 1.97196360558612 0.0856327897245145 0.326859798687036 GO:0051539 4 iron, 4 sulfur cluster binding 2/204 45/18639 0.0444444444444444 4.06078431372549 0.0869059425680063 0.329565392595557 GO:0004386 helicase activity 4/204 155/18639 0.0258064516129032 2.35787476280835 0.0907675287006139 0.341988624265539 GO:0004725 protein tyrosine phosphatase activity 3/204 98/18639 0.0306122448979592 2.79696878751501 0.0926308739156254 0.34677198953029 GO:0005543 phospholipid binding 9/204 497/18639 0.0181086519114688 1.65454491655817 0.096558316472995 0.355986395472463 GO:0001222 transcription corepressor binding 2/204 49/18639 0.0408163265306122 3.72929171668667 0.10039922833927 0.355986395472463 GO:0035254 glutamate receptor binding 2/204 49/18639 0.0408163265306122 3.72929171668667 0.10039922833927 0.355986395472463 GO:0008083 growth factor activity 4/204 162/18639 0.0246913580246914 2.25599128540305 0.102497573328034 0.355986395472463 GO:0061134 peptidase regulator activity 5/204 226/18639 0.0221238938053097 2.02140812077043 0.102973268666152 0.355986395472463 GO:0005131 growth hormone receptor binding 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0030957 Tat protein binding 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0035256 G protein-coupled glutamate receptor binding 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0043422 protein kinase B binding 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0047429 nucleoside triphosphate diphosphatase activity 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:1905394 retromer complex binding 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:1990757 ubiquitin ligase activator activity 1/204 10/18639 0.1 9.13676470588235 0.104235742509916 0.355986395472463 GO:0005021 vascular endothelial growth factor receptor activity 2/204 51/18639 0.0392156862745098 3.58304498269896 0.107350807481489 0.364493439355753 GO:0000149 SNARE binding 3/204 106/18639 0.0283018867924528 2.58587680355161 0.110495218675633 0.36516573607543 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0015173 aromatic amino acid transmembrane transporter activity 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0034056 estrogen response element binding 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0034713 type I transforming growth factor beta receptor binding 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0048185 activin binding 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0050786 RAGE receptor binding 1/204 11/18639 0.0909090909090909 8.30614973262032 0.114044959780193 0.36516573607543 GO:0140296 general transcription initiation factor binding 2/204 53/18639 0.0377358490566038 3.44783573806881 0.114426934420897 0.36516573607543 GO:0005496 steroid binding 3/204 108/18639 0.0277777777777778 2.53799019607843 0.115154803542077 0.365491332981375 GO:0003925 G protein activity 2/204 54/18639 0.037037037037037 3.38398692810457 0.118008987868827 0.368716386449825 GO:0140030 modification-dependent protein binding 4/204 173/18639 0.023121387283237 2.11254675280517 0.122249166783886 0.368716386449825 GO:0005025 transforming growth factor beta receptor activity, type I 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0005026 transforming growth factor beta receptor activity, type II 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0016361 activin receptor activity, type I 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0016362 activin receptor activity, type II 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0017002 activin receptor activity 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0017166 vinculin binding 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0035197 siRNA binding 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0035497 cAMP response element binding 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0045295 gamma-catenin binding 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0070679 inositol 1,4,5 trisphosphate binding 1/204 12/18639 0.0833333333333333 7.61397058823529 0.123747280383845 0.368716386449825 GO:0005200 structural constituent of cytoskeleton 3/204 112/18639 0.0267857142857143 2.44734768907563 0.12469121287092 0.369642986378769 GO:0004721 phosphoprotein phosphatase activity 4/204 175/18639 0.0228571428571429 2.08840336134454 0.126004675518163 0.371650154053572 GO:0016504 peptidase activator activity 2/204 57/18639 0.0350877192982456 3.20588235294118 0.128918546805114 0.378023380186388 GO:0008408 3'-5' exonuclease activity 2/204 58/18639 0.0344827586206897 3.15060851926978 0.132606155191348 0.378023380186388 GO:0061980 regulatory RNA binding 2/204 58/18639 0.0344827586206897 3.15060851926978 0.132606155191348 0.378023380186388 GO:0017154 semaphorin receptor activity 1/204 13/18639 0.0769230769230769 7.02828054298643 0.133343863558897 0.378023380186388 GO:0043560 insulin receptor substrate binding 1/204 13/18639 0.0769230769230769 7.02828054298643 0.133343863558897 0.378023380186388 GO:0046974 histone H3K9 methyltransferase activity 1/204 13/18639 0.0769230769230769 7.02828054298643 0.133343863558897 0.378023380186388 GO:0070123 transforming growth factor beta receptor activity, type III 1/204 13/18639 0.0769230769230769 7.02828054298643 0.133343863558897 0.378023380186388 GO:0071837 HMG box domain binding 1/204 13/18639 0.0769230769230769 7.02828054298643 0.133343863558897 0.378023380186388 GO:0042393 histone binding 5/204 247/18639 0.0202429149797571 1.84954751131222 0.135221198819034 0.381493623721333 GO:0031593 polyubiquitin modification-dependent protein binding 2/204 59/18639 0.0338983050847458 3.09720837487537 0.136317665971341 0.382738062150305 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/204 60/18639 0.0333333333333333 3.04558823529412 0.140052121412647 0.383489551184546 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/204 60/18639 0.0333333333333333 3.04558823529412 0.140052121412647 0.383489551184546 GO:0005545 1-phosphatidylinositol binding 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0008195 phosphatidate phosphatase activity 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0016530 metallochaperone activity 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0019992 diacylglycerol binding 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0034236 protein kinase A catalytic subunit binding 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0098821 BMP receptor activity 1/204 14/18639 0.0714285714285714 6.52626050420168 0.142835856033609 0.383489551184546 GO:0061135 endopeptidase regulator activity 4/204 184/18639 0.0217391304347826 1.98625319693095 0.143490041071883 0.383489551184546 GO:0019905 syntaxin binding 2/204 61/18639 0.0327868852459016 2.99566055930569 0.143808581694205 0.383489551184546 GO:0004540 RNA nuclease activity 3/204 121/18639 0.0247933884297521 2.26531356344191 0.147127778958972 0.390557376872907 GO:0004089 carbonate dehydratase activity 1/204 15/18639 0.0666666666666667 6.09117647058823 0.152224392160812 0.398650426107238 GO:0004559 alpha-mannosidase activity 1/204 15/18639 0.0666666666666667 6.09117647058823 0.152224392160812 0.398650426107238 GO:0140776 protein-containing complex destabilizing activity 1/204 15/18639 0.0666666666666667 6.09117647058823 0.152224392160812 0.398650426107238 GO:0004708 MAP kinase kinase activity 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0005024 transforming growth factor beta receptor activity 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0008142 oxysterol binding 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0015923 mannosidase activity 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0043023 ribosomal large subunit binding 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0070411 I-SMAD binding 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0097027 ubiquitin-protein transferase activator activity 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/204 16/18639 0.0625 5.71047794117647 0.161510594050803 0.408321155522375 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/204 128/18639 0.0234375 2.14142922794118 0.165414436170662 0.415359224476877 GO:0032934 sterol binding 2/204 68/18639 0.0294117647058824 2.68728373702422 0.17064463072153 0.415359224476877 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:0008429 phosphatidylethanolamine binding 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:0015278 intracellularly gated calcium channel activity 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:0019198 transmembrane receptor protein phosphatase activity 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:0030548 acetylcholine receptor regulator activity 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:1990226 histone methyltransferase binding 1/204 17/18639 0.0588235294117647 5.37456747404844 0.170695571702826 0.415359224476877 GO:0016887 ATP hydrolysis activity 7/204 417/18639 0.0167865707434053 1.53374947101143 0.174036773079097 0.416633996471922 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0004706 JUN kinase kinase kinase activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0004970 glutamate-gated receptor activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0015280 ligand-gated sodium channel activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0017128 phospholipid scramblase activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0031690 adrenergic receptor binding 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0034185 apolipoprotein binding 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0070628 proteasome binding 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0099602 neurotransmitter receptor regulator activity 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:1990381 ubiquitin-specific protease binding 1/204 18/18639 0.0555555555555556 5.07598039215686 0.179780423135144 0.416633996471922 GO:0005126 cytokine receptor binding 5/204 275/18639 0.0181818181818182 1.66122994652406 0.184202191890715 0.425193992348529 GO:0003714 transcription corepressor activity 4/204 204/18639 0.0196078431372549 1.79152249134948 0.185420073085305 0.425635061606222 GO:0019838 growth factor binding 3/204 136/18639 0.0220588235294118 2.01546280276817 0.187079099446989 0.425635061606222 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/204 19/18639 0.0526315789473684 4.80882352941176 0.188766234513719 0.425635061606222 GO:0042577 lipid phosphatase activity 1/204 19/18639 0.0526315789473684 4.80882352941176 0.188766234513719 0.425635061606222 GO:0043395 heparan sulfate proteoglycan binding 1/204 19/18639 0.0526315789473684 4.80882352941176 0.188766234513719 0.425635061606222 GO:0050145 nucleoside monophosphate kinase activity 1/204 19/18639 0.0526315789473684 4.80882352941176 0.188766234513719 0.425635061606222 GO:0061630 ubiquitin protein ligase activity 6/204 353/18639 0.0169971671388102 1.55299116813864 0.191304906644936 0.427861783350914 GO:0005516 calmodulin binding 4/204 207/18639 0.0193236714975845 1.76555839727195 0.192029605548914 0.427861783350914 GO:0004518 nuclease activity 4/204 209/18639 0.0191387559808612 1.74866310160428 0.196477039215906 0.427861783350914 GO:0000339 RNA cap binding 1/204 20/18639 0.05 4.56838235294118 0.197654080279519 0.427861783350914 GO:0016004 phospholipase activator activity 1/204 20/18639 0.05 4.56838235294118 0.197654080279519 0.427861783350914 GO:0052745 inositol phosphate phosphatase activity 1/204 20/18639 0.05 4.56838235294118 0.197654080279519 0.427861783350914 GO:0031267 small GTPase binding 5/204 283/18639 0.0176678445229682 1.61426938266473 0.199269780498109 0.427861783350914 GO:0051536 iron-sulfur cluster binding 2/204 76/18639 0.0263157894736842 2.40441176470588 0.202208710831334 0.427861783350914 GO:0003724 RNA helicase activity 2/204 77/18639 0.025974025974026 2.37318563789152 0.206203029108362 0.427861783350914 GO:0051540 metal cluster binding 2/204 77/18639 0.025974025974026 2.37318563789152 0.206203029108362 0.427861783350914 GO:0051010 microtubule plus-end binding 1/204 21/18639 0.0476190476190476 4.35084033613445 0.206445023274469 0.427861783350914 GO:0051428 peptide hormone receptor binding 1/204 21/18639 0.0476190476190476 4.35084033613445 0.206445023274469 0.427861783350914 GO:0061891 calcium ion sensor activity 1/204 21/18639 0.0476190476190476 4.35084033613445 0.206445023274469 0.427861783350914 GO:0072542 protein phosphatase activator activity 1/204 21/18639 0.0476190476190476 4.35084033613445 0.206445023274469 0.427861783350914 GO:0008186 ATP-dependent activity, acting on RNA 2/204 79/18639 0.0253164556962025 2.31310498883098 0.214216555612285 0.427861783350914 GO:0032931 histone H3K56 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0043992 histone H3K9 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0043993 histone H3K18 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0043994 histone H3K23 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0043999 histone H2AK5 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0044012 histone H2AK9 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0044014 histone H2BK5 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0044015 histone H2BK12 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0044016 histone H3K4 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0044017 histone H3K27 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0044018 histone H3K36 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0046972 histone H4K16 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0061133 endopeptidase activator activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0140784 metal ion sensor activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0140908 histone H3K122 acetyltransferase activity 1/204 22/18639 0.0454545454545455 4.15307486631016 0.215140114866048 0.427861783350914 GO:0015085 calcium ion transmembrane transporter activity 3/204 147/18639 0.0204081632653061 1.86464585834334 0.217961708270851 0.427861783350914 GO:0019209 kinase activator activity 3/204 148/18639 0.0202702702702703 1.85204689984102 0.220821715452469 0.427861783350914 GO:0033192 calmodulin-dependent protein phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0140791 histone H2AXS140 phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/204 81/18639 0.0246913580246914 2.25599128540305 0.222258929815966 0.427861783350914 GO:0004842 ubiquitin-protein transferase activity 7/204 449/18639 0.0155902004454343 1.42443993187475 0.222577234983395 0.427861783350914 GO:0003887 DNA-directed DNA polymerase activity 1/204 23/18639 0.0434782608695652 3.97250639386189 0.223740395070556 0.427861783350914 GO:0043274 phospholipase binding 1/204 23/18639 0.0434782608695652 3.97250639386189 0.223740395070556 0.427861783350914 GO:0044013 histone H2B acetyltransferase activity 1/204 23/18639 0.0434782608695652 3.97250639386189 0.223740395070556 0.427861783350914 GO:0070577 lysine-acetylated histone binding 1/204 23/18639 0.0434782608695652 3.97250639386189 0.223740395070556 0.427861783350914 GO:0061659 ubiquitin-like protein ligase activity 6/204 372/18639 0.0161290322580645 1.47367172675522 0.223796794610518 0.427861783350914 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/204 82/18639 0.024390243902439 2.22847919655667 0.226289356840903 0.427861783350914 GO:0033549 MAP kinase phosphatase activity 2/204 82/18639 0.024390243902439 2.22847919655667 0.226289356840903 0.427861783350914 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/204 83/18639 0.0240963855421687 2.20163004961021 0.230325127855071 0.427861783350914 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0030552 cAMP binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0043998 histone H2A acetyltransferase activity 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0050431 transforming growth factor beta binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0050699 WW domain binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0060229 lipase activator activity 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0070300 phosphatidic acid binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0070840 dynein complex binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0140033 acetylation-dependent protein binding 1/204 24/18639 0.0416666666666667 3.80698529411765 0.232246892675068 0.427861783350914 GO:0017018 myosin phosphatase activity 2/204 84/18639 0.0238095238095238 2.17542016806723 0.234365646548062 0.430407350893297 GO:0003707 nuclear steroid receptor activity 1/204 25/18639 0.04 3.65470588235294 0.240660625358081 0.433783349410862 GO:0004709 MAP kinase kinase kinase activity 1/204 25/18639 0.04 3.65470588235294 0.240660625358081 0.433783349410862 GO:0015662 P-type ion transporter activity 1/204 25/18639 0.04 3.65470588235294 0.240660625358081 0.433783349410862 GO:0017025 TBP-class protein binding 1/204 25/18639 0.04 3.65470588235294 0.240660625358081 0.433783349410862 GO:0019211 phosphatase activator activity 1/204 25/18639 0.04 3.65470588235294 0.240660625358081 0.433783349410862 GO:0140358 P-type transmembrane transporter activity 1/204 25/18639 0.04 3.65470588235294 0.240660625358081 0.433783349410862 GO:0005160 transforming growth factor beta receptor binding 1/204 26/18639 0.0384615384615385 3.51414027149321 0.248982599808868 0.440623752389028 GO:0008066 glutamate receptor activity 1/204 26/18639 0.0384615384615385 3.51414027149321 0.248982599808868 0.440623752389028 GO:0008157 protein phosphatase 1 binding 1/204 26/18639 0.0384615384615385 3.51414027149321 0.248982599808868 0.440623752389028 GO:0008198 ferrous iron binding 1/204 26/18639 0.0384615384615385 3.51414027149321 0.248982599808868 0.440623752389028 GO:0030247 polysaccharide binding 1/204 26/18639 0.0384615384615385 3.51414027149321 0.248982599808868 0.440623752389028 GO:0043548 phosphatidylinositol 3-kinase binding 1/204 26/18639 0.0384615384615385 3.51414027149321 0.248982599808868 0.440623752389028 GO:0140098 catalytic activity, acting on RNA 6/204 387/18639 0.0155038759689922 1.41655266757866 0.250645547731474 0.442226585725622 GO:0005044 scavenger receptor activity 1/204 27/18639 0.037037037037037 3.38398692810457 0.257213811845562 0.44839661527704 GO:0005104 fibroblast growth factor receptor binding 1/204 27/18639 0.037037037037037 3.38398692810457 0.257213811845562 0.44839661527704 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/204 27/18639 0.037037037037037 3.38398692810457 0.257213811845562 0.44839661527704 GO:0035255 ionotropic glutamate receptor binding 1/204 27/18639 0.037037037037037 3.38398692810457 0.257213811845562 0.44839661527704 GO:0004866 endopeptidase inhibitor activity 3/204 161/18639 0.0186335403726708 1.70250274022653 0.258611431928836 0.449491298352501 GO:0051020 GTPase binding 5/204 315/18639 0.0158730158730159 1.45028011204482 0.263216599134882 0.455786658749039 GO:0036408 histone H3K14 acetyltransferase activity 1/204 28/18639 0.0357142857142857 3.26313025210084 0.265355246531975 0.455786658749039 GO:0046966 nuclear thyroid hormone receptor binding 1/204 28/18639 0.0357142857142857 3.26313025210084 0.265355246531975 0.455786658749039 GO:0097718 disordered domain specific binding 1/204 28/18639 0.0357142857142857 3.26313025210084 0.265355246531975 0.455786658749039 GO:0043178 alcohol binding 2/204 92/18639 0.0217391304347826 1.98625319693095 0.26679312170997 0.456912560347867 GO:0019787 ubiquitin-like protein transferase activity 7/204 479/18639 0.0146137787056367 1.33522657497237 0.271884915591962 0.462812176589007 GO:0010484 histone H3 acetyltransferase activity 1/204 29/18639 0.0344827586206897 3.15060851926978 0.273407878293163 0.462812176589007 GO:0043236 laminin binding 1/204 29/18639 0.0344827586206897 3.15060851926978 0.273407878293163 0.462812176589007 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/204 29/18639 0.0344827586206897 3.15060851926978 0.273407878293163 0.462812176589007 GO:0042562 hormone binding 2/204 94/18639 0.0212765957446809 1.94399249061327 0.274909307539593 0.464008773419429 GO:0004867 serine-type endopeptidase inhibitor activity 2/204 95/18639 0.0210526315789474 1.92352941176471 0.278966072744643 0.46418542339374 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0031210 phosphatidylcholine binding 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0043995 histone H4K5 acetyltransferase activity 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0043996 histone H4K8 acetyltransferase activity 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0043997 histone H4K12 acetyltransferase activity 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0070566 adenylyltransferase activity 1/204 30/18639 0.0333333333333333 3.04558823529412 0.281372671029767 0.46418542339374 GO:0030414 peptidase inhibitor activity 3/204 169/18639 0.0177514792899408 1.62191089453533 0.282286023786449 0.464380388426158 GO:0005164 tumor necrosis factor receptor binding 1/204 31/18639 0.032258064516129 2.94734345351044 0.289250578231117 0.474500948558911 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/204 32/18639 0.03125 2.85523897058824 0.297042543087139 0.483211267863201 GO:0043425 bHLH transcription factor binding 1/204 32/18639 0.03125 2.85523897058824 0.297042543087139 0.483211267863201 GO:0051059 NF-kappaB binding 1/204 32/18639 0.03125 2.85523897058824 0.297042543087139 0.483211267863201 GO:0016755 aminoacyltransferase activity 7/204 496/18639 0.0141129032258065 1.28946276091082 0.30104394993067 0.488360185443086 GO:0019956 chemokine binding 1/204 33/18639 0.0303030303030303 2.76871657754011 0.304749498599055 0.490285694715835 GO:0140311 protein sequestering activity 1/204 33/18639 0.0303030303030303 2.76871657754011 0.304749498599055 0.490285694715835 GO:0140416 transcription regulator inhibitor activity 1/204 33/18639 0.0303030303030303 2.76871657754011 0.304749498599055 0.490285694715835 GO:0015171 amino acid transmembrane transporter activity 2/204 102/18639 0.0196078431372549 1.79152249134948 0.307296764118135 0.493025577596129 GO:0004722 protein serine/threonine phosphatase activity 2/204 103/18639 0.0194174757281553 1.77412906910337 0.311329419693297 0.495721366115005 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/204 34/18639 0.0294117647058824 2.68728373702422 0.312372367688907 0.495721366115005 GO:0051427 hormone receptor binding 1/204 34/18639 0.0294117647058824 2.68728373702422 0.312372367688907 0.495721366115005 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/204 34/18639 0.0294117647058824 2.68728373702422 0.312372367688907 0.495721366115005 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/204 181/18639 0.0165745856353591 1.51438089047774 0.318109947802598 0.500881085715327 GO:0005154 epidermal growth factor receptor binding 1/204 35/18639 0.0285714285714286 2.61050420168067 0.319912063307906 0.500881085715327 GO:0010485 histone H4 acetyltransferase activity 1/204 35/18639 0.0285714285714286 2.61050420168067 0.319912063307906 0.500881085715327 GO:0016229 steroid dehydrogenase activity 1/204 35/18639 0.0285714285714286 2.61050420168067 0.319912063307906 0.500881085715327 GO:0034061 DNA polymerase activity 1/204 35/18639 0.0285714285714286 2.61050420168067 0.319912063307906 0.500881085715327 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/204 36/18639 0.0277777777777778 2.53799019607843 0.327369488543617 0.505836559853348 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/204 36/18639 0.0277777777777778 2.53799019607843 0.327369488543617 0.505836559853348 GO:0045505 dynein intermediate chain binding 1/204 36/18639 0.0277777777777778 2.53799019607843 0.327369488543617 0.505836559853348 GO:0055106 ubiquitin-protein transferase regulator activity 1/204 36/18639 0.0277777777777778 2.53799019607843 0.327369488543617 0.505836559853348 GO:0019888 protein phosphatase regulator activity 2/204 107/18639 0.0186915887850467 1.70780648708081 0.327407910316037 0.505836559853348 GO:1901981 phosphatidylinositol phosphate binding 3/204 185/18639 0.0162162162162162 1.48163751987281 0.330083251661485 0.508624324459913 GO:0030551 cyclic nucleotide binding 1/204 37/18639 0.027027027027027 2.46939586645469 0.334745536726013 0.513100770204702 GO:0043394 proteoglycan binding 1/204 37/18639 0.027027027027027 2.46939586645469 0.334745536726013 0.513100770204702 GO:0005109 frizzled binding 1/204 38/18639 0.0263157894736842 2.40441176470588 0.342041091532372 0.521545685260849 GO:0042162 telomeric DNA binding 1/204 38/18639 0.0263157894736842 2.40441176470588 0.342041091532372 0.521545685260849 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/204 39/18639 0.0256410256410256 2.34276018099548 0.349257027091073 0.531161728701007 GO:0030331 nuclear estrogen receptor binding 1/204 40/18639 0.025 2.28419117647059 0.356394208084268 0.537814515558689 GO:0050997 quaternary ammonium group binding 1/204 40/18639 0.025 2.28419117647059 0.356394208084268 0.537814515558689 GO:0071855 neuropeptide receptor binding 1/204 40/18639 0.025 2.28419117647059 0.356394208084268 0.537814515558689 GO:0001221 transcription coregulator binding 2/204 115/18639 0.0173913043478261 1.58900255754476 0.359242212448468 0.540715082654396 GO:0001727 lipid kinase activity 1/204 41/18639 0.024390243902439 2.22847919655667 0.36345348984946 0.544248302748935 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/204 41/18639 0.024390243902439 2.22847919655667 0.36345348984946 0.544248302748935 GO:0019208 phosphatase regulator activity 2/204 117/18639 0.0170940170940171 1.56184012066365 0.367118718650041 0.544923072020951 GO:0004402 histone acetyltransferase activity 1/204 42/18639 0.0238095238095238 2.17542016806723 0.370435718479996 0.544923072020951 GO:0004520 DNA endonuclease activity 1/204 42/18639 0.0238095238095238 2.17542016806723 0.370435718479996 0.544923072020951 GO:0008307 structural constituent of muscle 1/204 42/18639 0.0238095238095238 2.17542016806723 0.370435718479996 0.544923072020951 GO:0035198 miRNA binding 1/204 42/18639 0.0238095238095238 2.17542016806723 0.370435718479996 0.544923072020951 GO:0048487 beta-tubulin binding 1/204 42/18639 0.0238095238095238 2.17542016806723 0.370435718479996 0.544923072020951 GO:0051879 Hsp90 protein binding 1/204 42/18639 0.0238095238095238 2.17542016806723 0.370435718479996 0.544923072020951 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/204 43/18639 0.0232558139534884 2.12482900136799 0.377341730924481 0.552299676340593 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/204 43/18639 0.0232558139534884 2.12482900136799 0.377341730924481 0.552299676340593 GO:0001046 core promoter sequence-specific DNA binding 1/204 44/18639 0.0227272727272727 2.07653743315508 0.384172355085129 0.554805824346476 GO:0001223 transcription coactivator binding 1/204 44/18639 0.0227272727272727 2.07653743315508 0.384172355085129 0.554805824346476 GO:0019205 nucleobase-containing compound kinase activity 1/204 44/18639 0.0227272727272727 2.07653743315508 0.384172355085129 0.554805824346476 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/204 44/18639 0.0227272727272727 2.07653743315508 0.384172355085129 0.554805824346476 GO:0043014 alpha-tubulin binding 1/204 44/18639 0.0227272727272727 2.07653743315508 0.384172355085129 0.554805824346476 GO:0019207 kinase regulator activity 4/204 287/18639 0.0139372822299652 1.27341668374667 0.384754039144388 0.554805824346476 GO:0046915 transition metal ion transmembrane transporter activity 1/204 45/18639 0.0222222222222222 2.03039215686274 0.390928409915063 0.56093904518525 GO:0140303 intramembrane lipid transporter activity 1/204 45/18639 0.0222222222222222 2.03039215686274 0.390928409915063 0.56093904518525 GO:0030276 clathrin binding 1/204 46/18639 0.0217391304347826 1.98625319693095 0.397610705514575 0.566647060851272 GO:0030291 protein serine/threonine kinase inhibitor activity 1/204 46/18639 0.0217391304347826 1.98625319693095 0.397610705514575 0.566647060851272 GO:0001784 phosphotyrosine residue binding 1/204 47/18639 0.0212765957446809 1.94399249061327 0.40422004322635 0.566647060851272 GO:0061733 protein-lysine-acetyltransferase activity 1/204 47/18639 0.0212765957446809 1.94399249061327 0.40422004322635 0.566647060851272 GO:0061749 forked DNA-dependent helicase activity 1/204 47/18639 0.0212765957446809 1.94399249061327 0.40422004322635 0.566647060851272 GO:0140938 histone H3 methyltransferase activity 1/204 47/18639 0.0212765957446809 1.94399249061327 0.40422004322635 0.566647060851272 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/204 47/18639 0.0212765957446809 1.94399249061327 0.40422004322635 0.566647060851272 GO:0042826 histone deacetylase binding 2/204 127/18639 0.015748031496063 1.43886058360352 0.405899370034787 0.566647060851272 GO:0009378 four-way junction helicase activity 1/204 48/18639 0.0208333333333333 1.90349264705882 0.410757215729675 0.566647060851272 GO:0032266 phosphatidylinositol-3-phosphate binding 1/204 48/18639 0.0208333333333333 1.90349264705882 0.410757215729675 0.566647060851272 GO:0036121 double-stranded DNA helicase activity 1/204 48/18639 0.0208333333333333 1.90349264705882 0.410757215729675 0.566647060851272 GO:0043138 3'-5' DNA helicase activity 1/204 48/18639 0.0208333333333333 1.90349264705882 0.410757215729675 0.566647060851272 GO:0140693 molecular condensate scaffold activity 1/204 48/18639 0.0208333333333333 1.90349264705882 0.410757215729675 0.566647060851272 GO:0005004 GPI-linked ephrin receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0005008 hepatocyte growth factor receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0005009 insulin receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0005011 macrophage colony-stimulating factor receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0005020 stem cell factor receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0008288 boss receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0036332 placental growth factor receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0038062 protein tyrosine kinase collagen receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0060175 brain-derived neurotrophic factor receptor activity 1/204 49/18639 0.0204081632653061 1.86464585834334 0.417223007133642 0.566647060851272 GO:0005262 calcium channel activity 2/204 131/18639 0.0152671755725191 1.39492590929502 0.421095916519639 0.567415194386463 GO:0005006 epidermal growth factor receptor activity 1/204 50/18639 0.02 1.82735294117647 0.423618193069346 0.567415194386463 GO:0005007 fibroblast growth factor receptor activity 1/204 50/18639 0.02 1.82735294117647 0.423618193069346 0.567415194386463 GO:0005017 platelet-derived growth factor receptor activity 1/204 50/18639 0.02 1.82735294117647 0.423618193069346 0.567415194386463 GO:0005019 platelet-derived growth factor beta-receptor activity 1/204 50/18639 0.02 1.82735294117647 0.423618193069346 0.567415194386463 GO:0032813 tumor necrosis factor receptor superfamily binding 1/204 50/18639 0.02 1.82735294117647 0.423618193069346 0.567415194386463 GO:0003743 translation initiation factor activity 1/204 51/18639 0.0196078431372549 1.79152249134948 0.429943540781103 0.56781196809692 GO:0005010 insulin-like growth factor receptor activity 1/204 51/18639 0.0196078431372549 1.79152249134948 0.429943540781103 0.56781196809692 GO:0005030 neurotrophin receptor activity 1/204 51/18639 0.0196078431372549 1.79152249134948 0.429943540781103 0.56781196809692 GO:0005048 signal sequence binding 1/204 51/18639 0.0196078431372549 1.79152249134948 0.429943540781103 0.56781196809692 GO:0005272 sodium channel activity 1/204 51/18639 0.0196078431372549 1.79152249134948 0.429943540781103 0.56781196809692 GO:0016830 carbon-carbon lyase activity 1/204 51/18639 0.0196078431372549 1.79152249134948 0.429943540781103 0.56781196809692 GO:0005080 protein kinase C binding 1/204 52/18639 0.0192307692307692 1.75707013574661 0.436199809216688 0.56781196809692 GO:0016779 nucleotidyltransferase activity 2/204 136/18639 0.0147058823529412 1.34364186851211 0.43980920892441 0.56781196809692 GO:0044325 transmembrane transporter binding 2/204 136/18639 0.0147058823529412 1.34364186851211 0.43980920892441 0.56781196809692 GO:0099094 ligand-gated monoatomic cation channel activity 2/204 136/18639 0.0147058823529412 1.34364186851211 0.43980920892441 0.56781196809692 GO:0004864 protein phosphatase inhibitor activity 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0005003 ephrin receptor activity 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0005005 transmembrane-ephrin receptor activity 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0005544 calcium-dependent phospholipid binding 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0017046 peptide hormone binding 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0034212 protein N-acetyltransferase activity 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0038064 collagen receptor activity 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0051018 protein kinase A binding 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/204 53/18639 0.0188679245283019 1.72391786903441 0.442387749116607 0.56781196809692 GO:0015485 cholesterol binding 1/204 54/18639 0.0185185185185185 1.69199346405229 0.448508103102414 0.573148210529125 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/204 54/18639 0.0185185185185185 1.69199346405229 0.448508103102414 0.573148210529125 GO:0030295 protein kinase activator activity 2/204 139/18639 0.0143884892086331 1.31464240372408 0.45087838691754 0.574919165851187 GO:0140313 molecular sequestering activity 1/204 55/18639 0.0181818181818182 1.66122994652406 0.454561605764083 0.578352892736872 GO:0019212 phosphatase inhibitor activity 1/204 56/18639 0.0178571428571429 1.63156512605042 0.46054898374644 0.583428647522605 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/204 56/18639 0.0178571428571429 1.63156512605042 0.46054898374644 0.583428647522605 GO:0000287 magnesium ion binding 3/204 230/18639 0.0130434782608696 1.19175191815857 0.46215264120699 0.584192949058186 GO:0017116 single-stranded DNA helicase activity 1/204 58/18639 0.0172413793103448 1.57530425963489 0.472328233038947 0.595766064999449 GO:0001786 phosphatidylserine binding 1/204 59/18639 0.0169491525423729 1.54860418743769 0.478121518678043 0.599190916111539 GO:0036002 pre-mRNA binding 1/204 59/18639 0.0169491525423729 1.54860418743769 0.478121518678043 0.599190916111539 GO:0045309 protein phosphorylated amino acid binding 1/204 59/18639 0.0169491525423729 1.54860418743769 0.478121518678043 0.599190916111539 GO:0004857 enzyme inhibitor activity 5/204 416/18639 0.0120192307692308 1.09816883484163 0.479665689140505 0.599838891773136 GO:0001098 basal transcription machinery binding 1/204 60/18639 0.0166666666666667 1.52279411764706 0.483851508462203 0.602493136336731 GO:0001099 basal RNA polymerase II transcription machinery binding 1/204 60/18639 0.0166666666666667 1.52279411764706 0.483851508462203 0.602493136336731 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/204 61/18639 0.0163934426229508 1.49783027965284 0.489518890575003 0.606961851583443 GO:0016836 hydro-lyase activity 1/204 61/18639 0.0163934426229508 1.49783027965284 0.489518890575003 0.606961851583443 GO:0003924 GTPase activity 4/204 331/18639 0.0120845921450151 1.10414074995557 0.491495151907371 0.608121120156578 GO:0015179 L-amino acid transmembrane transporter activity 1/204 62/18639 0.0161290322580645 1.47367172675522 0.495124345754392 0.611316316956797 GO:0022824 transmitter-gated monoatomic ion channel activity 1/204 63/18639 0.0158730158730159 1.45028011204482 0.500668547372851 0.615558803506831 GO:0022835 transmitter-gated channel activity 1/204 63/18639 0.0158730158730159 1.45028011204482 0.500668547372851 0.615558803506831 GO:0004536 DNA nuclease activity 1/204 64/18639 0.015625 1.42761948529412 0.506152161516689 0.620993408247366 GO:0038024 cargo receptor activity 1/204 65/18639 0.0153846153846154 1.40565610859729 0.5115758470645 0.626331854686936 GO:0016500 protein-hormone receptor activity 1/204 67/18639 0.0149253731343284 1.36369622475856 0.522246032312663 0.63539933931374 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/204 67/18639 0.0149253731343284 1.36369622475856 0.522246032312663 0.63539933931374 GO:0042054 histone methyltransferase activity 1/204 67/18639 0.0149253731343284 1.36369622475856 0.522246032312663 0.63539933931374 GO:0005548 phospholipid transporter activity 1/204 68/18639 0.0147058823529412 1.34364186851211 0.527493814425964 0.637474573822576 GO:0030145 manganese ion binding 1/204 68/18639 0.0147058823529412 1.34364186851211 0.527493814425964 0.637474573822576 GO:1990841 promoter-specific chromatin binding 1/204 68/18639 0.0147058823529412 1.34364186851211 0.527493814425964 0.637474573822576 GO:0019887 protein kinase regulator activity 3/204 255/18639 0.0117647058823529 1.07491349480969 0.530711750233431 0.637474573822576 GO:0002039 p53 binding 1/204 69/18639 0.0144927536231884 1.32416879795396 0.532684232920235 0.637474573822576 GO:0008080 N-acetyltransferase activity 1/204 69/18639 0.0144927536231884 1.32416879795396 0.532684232920235 0.637474573822576 GO:0016279 protein-lysine N-methyltransferase activity 1/204 69/18639 0.0144927536231884 1.32416879795396 0.532684232920235 0.637474573822576 GO:0098960 postsynaptic neurotransmitter receptor activity 1/204 69/18639 0.0144927536231884 1.32416879795396 0.532684232920235 0.637474573822576 GO:0016278 lysine N-methyltransferase activity 1/204 70/18639 0.0142857142857143 1.30525210084034 0.537817911783146 0.642301964174555 GO:0140299 molecular sensor activity 1/204 71/18639 0.0140845070422535 1.28686826843413 0.54289546824802 0.647042762156824 GO:0004521 RNA endonuclease activity 1/204 73/18639 0.0136986301369863 1.25161160354553 0.552884649580923 0.656269584055404 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/204 73/18639 0.0136986301369863 1.25161160354553 0.552884649580923 0.656269584055404 GO:0003678 DNA helicase activity 1/204 74/18639 0.0135135135135135 1.23469793322735 0.557797475794727 0.659420497700649 GO:0035064 methylated histone binding 1/204 74/18639 0.0135135135135135 1.23469793322735 0.557797475794727 0.659420497700649 GO:0019003 GDP binding 1/204 75/18639 0.0133333333333333 1.21823529411765 0.562656582443683 0.663821099287093 GO:0017022 myosin binding 1/204 76/18639 0.0131578947368421 1.20220588235294 0.567462554065181 0.666797045420656 GO:0140034 methylation-dependent protein binding 1/204 76/18639 0.0131578947368421 1.20220588235294 0.567462554065181 0.666797045420656 GO:0016835 carbon-oxygen lyase activity 1/204 79/18639 0.0126582278481013 1.15655249441549 0.581567409606786 0.681998729338078 GO:0048306 calcium-dependent protein binding 1/204 80/18639 0.0125 1.14209558823529 0.586166560923608 0.68601457230338 GO:0001618 virus receptor activity 1/204 81/18639 0.0123456790123457 1.12799564270152 0.590715406312453 0.68857843769755 GO:0015101 organic cation transmembrane transporter activity 1/204 81/18639 0.0123456790123457 1.12799564270152 0.590715406312453 0.68857843769755 GO:0140272 exogenous protein binding 1/204 82/18639 0.0121951219512195 1.11423959827834 0.595214493342966 0.692230729971429 GO:0005525 GTP binding 4/204 378/18639 0.0105820105820106 0.966853408029879 0.596219275985666 0.692230729971429 GO:0008135 translation factor activity, RNA binding 1/204 83/18639 0.0120481927710843 1.1008150248051 0.599664363653794 0.694849183281381 GO:0004860 protein kinase inhibitor activity 1/204 84/18639 0.0119047619047619 1.08771008403361 0.604065553016514 0.69580726422415 GO:0051117 ATPase binding 1/204 84/18639 0.0119047619047619 1.08771008403361 0.604065553016514 0.69580726422415 GO:0180051 translation factor activity 1/204 84/18639 0.0119047619047619 1.08771008403361 0.604065553016514 0.69580726422415 GO:0015276 ligand-gated monoatomic ion channel activity 2/204 186/18639 0.010752688172043 0.982447817836812 0.606467695509386 0.697199083026538 GO:0022834 ligand-gated channel activity 2/204 188/18639 0.0106382978723404 0.971996245306633 0.612297693137155 0.69888831595306 GO:0046943 carboxylic acid transmembrane transporter activity 2/204 188/18639 0.0106382978723404 0.971996245306633 0.612297693137155 0.69888831595306 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/204 86/18639 0.0116279069767442 1.06241450068399 0.61272400302734 0.69888831595306 GO:0016209 antioxidant activity 1/204 86/18639 0.0116279069767442 1.06241450068399 0.61272400302734 0.69888831595306 GO:0005342 organic acid transmembrane transporter activity 2/204 189/18639 0.0105820105820106 0.966853408029879 0.6151880142792 0.700330994812968 GO:0019902 phosphatase binding 2/204 190/18639 0.0105263157894737 0.961764705882353 0.618061896438516 0.702233750039092 GO:0004197 cysteine-type endopeptidase activity 1/204 88/18639 0.0113636363636364 1.03826871657754 0.621194014592854 0.704421950528595 GO:0019210 kinase inhibitor activity 1/204 90/18639 0.0111111111111111 1.01519607843137 0.629479669034765 0.712434354101362 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/204 91/18639 0.010989010989011 1.00404007756949 0.633554613641855 0.714277788352979 GO:0072341 modified amino acid binding 1/204 91/18639 0.010989010989011 1.00404007756949 0.633554613641855 0.714277788352979 GO:0019001 guanyl nucleotide binding 4/204 400/18639 0.01 0.913676470588235 0.640638108644584 0.719150818984776 GO:0032561 guanyl ribonucleotide binding 4/204 400/18639 0.01 0.913676470588235 0.640638108644584 0.719150818984776 GO:0051219 phosphoprotein binding 1/204 93/18639 0.010752688172043 0.982447817836812 0.641571192964158 0.719150818984776 GO:0016410 N-acyltransferase activity 1/204 94/18639 0.0106382978723404 0.971996245306633 0.645513793882702 0.721234395718713 GO:0016829 lyase activity 2/204 200/18639 0.01 0.913676470588235 0.645899981097409 0.721234395718713 GO:0008276 protein methyltransferase activity 1/204 95/18639 0.0105263157894737 0.961764705882353 0.649413237724596 0.723773532120542 GO:0004896 cytokine receptor activity 1/204 96/18639 0.0104166666666667 0.951746323529412 0.653269994600361 0.72530356814945 GO:0016407 acetyltransferase activity 1/204 96/18639 0.0104166666666667 0.951746323529412 0.653269994600361 0.72530356814945 GO:0030594 neurotransmitter receptor activity 1/204 97/18639 0.0103092783505155 0.941934505761067 0.657084529524674 0.728154393249354 GO:0008170 N-methyltransferase activity 1/204 98/18639 0.0102040816326531 0.932322929171669 0.660857302471333 0.729566473805782 GO:0042626 ATPase-coupled transmembrane transporter activity 1/204 98/18639 0.0102040816326531 0.932322929171669 0.660857302471333 0.729566473805782 GO:0051015 actin filament binding 2/204 209/18639 0.00956937799043062 0.874331550802139 0.6695673811081 0.737787453900246 GO:1902936 phosphatidylinositol bisphosphate binding 1/204 111/18639 0.00900900900900901 0.823131955484897 0.706303453865227 0.77680078541863 GO:0043022 ribosome binding 1/204 112/18639 0.00892857142857143 0.81578256302521 0.709537159360234 0.778890415538302 GO:0005261 monoatomic cation channel activity 3/204 341/18639 0.00879765395894428 0.803820941866483 0.724217336196609 0.793513929341125 GO:0022853 active monoatomic ion transmembrane transporter activity 1/204 118/18639 0.00847457627118644 0.774302093718844 0.72820870350744 0.795384015511824 GO:0005125 cytokine activity 2/204 234/18639 0.00854700854700855 0.780920060331825 0.728648027908948 0.795384015511824 GO:0003697 single-stranded DNA binding 1/204 121/18639 0.00826446280991736 0.755104521147302 0.737091575392488 0.803099776173905 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/204 122/18639 0.00819672131147541 0.748915139826422 0.739987855693813 0.804754018110218 GO:0005267 potassium channel activity 1/204 124/18639 0.00806451612903226 0.736835863377609 0.745685507805444 0.809443004755352 GO:0004519 endonuclease activity 1/204 127/18639 0.0078740157480315 0.71943029180176 0.753999854489606 0.815436879670241 GO:0019783 ubiquitin-like protein peptidase activity 1/204 127/18639 0.0078740157480315 0.71943029180176 0.753999854489606 0.815436879670241 GO:0035591 signaling adaptor activity 1/204 129/18639 0.00775193798449612 0.70827633378933 0.759391909297109 0.819582876638305 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/204 130/18639 0.00769230769230769 0.702828054298643 0.762043667833218 0.819582876638305 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/204 130/18639 0.00769230769230769 0.702828054298643 0.762043667833218 0.819582876638305 GO:0031072 heat shock protein binding 1/204 131/18639 0.00763358778625954 0.697462954647508 0.764666342843323 0.820659316890987 GO:0005179 hormone activity 1/204 132/18639 0.00757575757575758 0.692179144385027 0.76726025175082 0.820659316890987 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/204 132/18639 0.00757575757575758 0.692179144385027 0.76726025175082 0.820659316890987 GO:0051087 protein-folding chaperone binding 1/204 134/18639 0.00746268656716418 0.68184811237928 0.772363023751555 0.823814333982932 GO:0003713 transcription coactivator activity 2/204 256/18639 0.0078125 0.713809742647059 0.773031258600423 0.823814333982932 GO:0003730 mRNA 3'-UTR binding 2/204 262/18639 0.00763358778625954 0.697462954647508 0.783988858589866 0.831630957326299 GO:0140101 catalytic activity, acting on a tRNA 1/204 139/18639 0.00719424460431655 0.65732120186204 0.784638112134916 0.831630957326299 GO:0140767 enzyme-substrate adaptor activity 1/204 139/18639 0.00719424460431655 0.65732120186204 0.784638112134916 0.831630957326299 GO:0020037 heme binding 1/204 142/18639 0.00704225352112676 0.643434134217067 0.791684620668074 0.837579381286513 GO:0008514 organic anion transmembrane transporter activity 2/204 269/18639 0.00743494423791822 0.679313361032145 0.796185947822214 0.837860431975998 GO:0015631 tubulin binding 3/204 385/18639 0.00779220779220779 0.711955691367456 0.796187790613155 0.837860431975998 GO:0019903 protein phosphatase binding 1/204 144/18639 0.00694444444444444 0.634497549019608 0.796254348881299 0.837860431975998 GO:0046906 tetrapyrrole binding 1/204 152/18639 0.00657894736842105 0.601102941176471 0.813557067415527 0.853592819061898 GO:0030246 carbohydrate binding 2/204 280/18639 0.00714285714285714 0.652626050420168 0.814128767495681 0.853592819061898 GO:0005506 iron ion binding 1/204 154/18639 0.00649350649350649 0.59329640947288 0.817649188929983 0.855747538234965 GO:0140375 immune receptor activity 1/204 156/18639 0.00641025641025641 0.585690045248869 0.821651925622197 0.858398433923726 GO:0015079 potassium ion transmembrane transporter activity 1/204 160/18639 0.00625 0.571047794117647 0.829396974656693 0.864942559284837 GO:0015081 sodium ion transmembrane transporter activity 1/204 164/18639 0.00609756097560976 0.557119799139168 0.8368072598327 0.871114865850796 GO:0015399 primary active transmembrane transporter activity 1/204 166/18639 0.00602409638554217 0.550407512402551 0.840391390772937 0.8732892743975 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/204 167/18639 0.00598802395209581 0.547111659034871 0.842153971635944 0.873566464361263 GO:0031625 ubiquitin protein ligase binding 2/204 302/18639 0.00662251655629139 0.605083755356447 0.845848777672699 0.875843415178823 GO:0043021 ribonucleoprotein complex binding 1/204 177/18639 0.00564971751412429 0.516201395812562 0.858748629466133 0.887626901961454 GO:0005319 lipid transporter activity 1/204 178/18639 0.00561797752808989 0.513301387970919 0.860309418090817 0.887669081563669 GO:0022836 gated channel activity 2/204 318/18639 0.00628930817610063 0.574639289678135 0.865754727027241 0.891712099795253 GO:0044389 ubiquitin-like protein ligase binding 2/204 322/18639 0.0062111801242236 0.567500913408842 0.870350648165757 0.891933713080377 GO:0005216 monoatomic ion channel activity 3/204 448/18639 0.00669642857142857 0.611836922268908 0.871499661696366 0.891933713080377 GO:0046873 metal ion transmembrane transporter activity 3/204 450/18639 0.00666666666666667 0.609117647058824 0.873428672112971 0.891933713080377 GO:0008234 cysteine-type peptidase activity 1/204 187/18639 0.0053475935828877 0.488597043095313 0.873606308017081 0.891933713080377 GO:0031406 carboxylic acid binding 1/204 187/18639 0.0053475935828877 0.488597043095313 0.873606308017081 0.891933713080377 GO:0043177 organic acid binding 1/204 189/18639 0.00529100529100529 0.483426704014939 0.876385678512624 0.893209836389829 GO:0008168 methyltransferase activity 1/204 204/18639 0.00490196078431373 0.44788062283737 0.895380981439071 0.910979953241145 GO:0016741 transferase activity, transferring one-carbon groups 1/204 215/18639 0.00465116279069767 0.424965800273598 0.907437094616959 0.921640457837051 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/204 229/18639 0.00436681222707424 0.398985358335474 0.920801817289195 0.933590731418212 GO:0033218 amide binding 1/204 247/18639 0.00404858299595142 0.369909502262443 0.935201008596447 0.946353355820697 GO:0042277 peptide binding 1/204 249/18639 0.00401606425702811 0.366938341601701 0.936630547370484 0.946353355820697 GO:0008017 microtubule binding 1/204 276/18639 0.0036231884057971 0.331042199488491 0.953120363459044 0.961351109257482 GO:0015291 secondary active transmembrane transporter activity 1/204 287/18639 0.00348432055749129 0.318354170936667 0.958542715128165 0.965153354542842 GO:0022804 active transmembrane transporter activity 2/204 457/18639 0.00437636761487965 0.399858411635989 0.961995479665839 0.966962754087521 GO:0030371 translation repressor activity 1/204 329/18639 0.00303951367781155 0.277713212944752 0.974089427279761 0.977436813627802 GO:0045182 translation regulator activity 1/204 356/18639 0.00280898876404494 0.256650693985459 0.980857187013054 0.982539617865564 GO:0004175 endopeptidase activity 1/204 405/18639 0.00246913580246914 0.225599128540305 0.988961493582761 0.988961493582761