ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005096 GTPase activator activity 43/946 271/18639 0.158671586715867 3.12629989936263 2.60843798054001e-11 2.57911644681846e-08 GO:0030695 GTPase regulator activity 61/946 489/18639 0.124744376278119 2.45783343493431 7.4023210021202e-11 2.57911644681846e-08 GO:0060589 nucleoside-triphosphatase regulator activity 61/946 490/18639 0.124489795918367 2.4528174483324 8.05285428728413e-11 2.57911644681846e-08 GO:0106310 protein serine kinase activity 50/946 361/18639 0.138504155124654 2.7289418048292 1.01740293760097e-10 2.57911644681846e-08 GO:0003712 transcription coregulator activity 60/946 495/18639 0.121212121212121 2.38823755525658 3.37356454164691e-10 6.84158889045993e-08 GO:0004674 protein serine/threonine kinase activity 52/946 433/18639 0.120092378752887 2.36617531456137 7.16310103648628e-09 1.21056407516618e-06 GO:0019787 ubiquitin-like protein transferase activity 52/946 479/18639 0.108559498956159 2.13894344719222 1.98539826499804e-07 2.87599120101145e-05 GO:0141003 histone H2AX kinase activity 42/946 354/18639 0.11864406779661 2.33763930196725 2.81804599827245e-07 3.57187330281032e-05 GO:0140996 histone H3 kinase activity 42/946 357/18639 0.117647058823529 2.31799527421962 3.54742425890392e-07 3.99676466503176e-05 GO:0035173 histone kinase activity 42/946 360/18639 0.116666666666667 2.29867864693446 4.45066538785186e-07 4.51297470328178e-05 GO:0016755 aminoacyltransferase activity 52/946 496/18639 0.104838709677419 2.0656328854941 5.87746230927326e-07 5.41795161963917e-05 GO:0003713 transcription coactivator activity 33/946 256/18639 0.12890625 2.53983466569767 8.32029003787455e-07 7.03064508200399e-05 GO:0004842 ubiquitin-protein transferase activity 48/946 449/18639 0.106904231625835 2.10632978147351 9.13929139770874e-07 7.12864729021282e-05 GO:0140857 histone H3T45 kinase activity 30/946 246/18639 0.121951219512195 2.402799979374 8.04132321896932e-06 0.000552328044400845 GO:0035091 phosphatidylinositol binding 33/946 284/18639 0.116197183098592 2.28942843105142 8.17053320119593e-06 0.000552328044400845 GO:0061659 ubiquitin-like protein ligase activity 39/946 372/18639 0.104838709677419 2.0656328854941 1.49650978829895e-05 0.000580548924338593 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 29/946 243/18639 0.119341563786008 2.35138203742855 1.71515554994265e-05 0.000580548924338593 GO:0031267 small GTPase binding 32/946 283/18639 0.113074204946996 2.22789651797787 1.94223658828449e-05 0.000580548924338593 GO:0004676 3-phosphoinositide-dependent protein kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0004711 ribosomal protein S6 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0035175 histone H3S10 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0035979 histone H2AXS139 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0044022 histone H3S28 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0044023 histone H4S1 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0044024 histone H2AS1 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0044025 histone H2BS14 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0072354 histone H3T3 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0072371 histone H2AS121 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0072518 Rho-dependent protein serine/threonine kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0140823 histone H2BS36 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0140855 histone H3S57 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0140995 histone H2A kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0140997 histone H4 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0140998 histone H2B kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:1990244 histone H2AT120 kinase activity 29/946 245/18639 0.118367346938776 2.33218708202097 2.00386709584327e-05 0.000580548924338593 GO:0004677 DNA-dependent protein kinase activity 29/946 246/18639 0.117886178861789 2.3227066467282 2.16420031448127e-05 0.00060958308857889 GO:0035402 histone H3T11 kinase activity 29/946 247/18639 0.117408906882591 2.31330297609367 2.33610653401774e-05 0.000623371585656312 GO:0035403 histone H3T6 kinase activity 29/946 247/18639 0.117408906882591 2.31330297609367 2.33610653401774e-05 0.000623371585656312 GO:0004679 AMP-activated protein kinase activity 29/946 248/18639 0.116935483870968 2.30397514151265 2.5203247848159e-05 0.000655284444052133 GO:0051020 GTPase binding 34/946 315/18639 0.107936507936508 2.12666868015705 2.86480472048079e-05 0.000726227996641881 GO:0140297 DNA-binding transcription factor binding 46/946 488/18639 0.0942622950819672 1.85724621356531 4.08050425962064e-05 0.00100917837055008 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 36/946 349/18639 0.103151862464183 2.0323970026109 4.44144371512423e-05 0.00107229141122285 GO:0061630 ubiquitin protein ligase activity 36/946 353/18639 0.101983002832861 2.00936700824704 5.63328953727373e-05 0.0013284082769292 GO:1901981 phosphatidylinositol phosphate binding 23/946 185/18639 0.124324324324324 2.44955716816182 6.58990954890301e-05 0.00151867460967901 GO:0000149 SNARE binding 16/946 106/18639 0.150943396226415 2.97403167258367 8.56805830392586e-05 0.00193066913781796 GO:0005543 phospholipid binding 45/946 497/18639 0.0905432595573441 1.7839702060141 0.000126607872060416 0.00279087787541873 GO:0070064 proline-rich region binding 6/946 18/18639 0.333333333333333 6.5676532769556 0.00018439810133557 0.00397829095221846 GO:0045295 gamma-catenin binding 5/946 12/18639 0.416666666666667 8.2095665961945 0.000195655167633296 0.00410128718365677 GO:0016922 nuclear receptor binding 18/946 137/18639 0.131386861313869 2.58871005077082 0.000198188433924243 0.00410128718365677 GO:0045296 cadherin binding 33/946 334/18639 0.0988023952095808 1.9466996240078 0.000205240856478825 0.00416228456939058 GO:0003714 transcription corepressor activity 23/946 204/18639 0.112745098039216 2.22141213779381 0.000287774636768348 0.00572163689574715 GO:0005154 epidermal growth factor receptor binding 8/946 35/18639 0.228571428571429 4.5035336756267 0.000295456902226234 0.00576140959341156 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/946 29/18639 0.241379310344828 4.75588685572647 0.000495342829279837 0.00930143757203249 GO:0097472 cyclin-dependent protein kinase activity 7/946 29/18639 0.241379310344828 4.75588685572647 0.000495342829279837 0.00930143757203249 GO:0004721 phosphoprotein phosphatase activity 20/946 175/18639 0.114285714285714 2.25176683781335 0.000586468759055202 0.0108123513033086 GO:0019902 phosphatase binding 21/946 190/18639 0.110526315789474 2.1776955602537 0.000674950016643455 0.012221416372794 GO:0045309 protein phosphorylated amino acid binding 10/946 59/18639 0.169491525423729 3.33948471709607 0.00070460541666102 0.0125345595174434 GO:0048156 tau protein binding 8/946 43/18639 0.186046511627907 3.66566694527755 0.00127090351757113 0.0222188994278815 GO:0030332 cyclin binding 7/946 34/18639 0.205882352941176 4.05649172988434 0.00136837203155809 0.0235174447457611 GO:0052742 phosphatidylinositol kinase activity 6/946 26/18639 0.230769230769231 4.54683688404619 0.0016143382681553 0.0268946614250819 GO:0043130 ubiquitin binding 13/946 100/18639 0.13 2.56138477801269 0.00161792341906311 0.0268946614250819 GO:0004713 protein tyrosine kinase activity 16/946 140/18639 0.114285714285714 2.25176683781335 0.00199491641848749 0.032185765017221 GO:0030276 clathrin binding 8/946 46/18639 0.173913043478261 3.42660170971597 0.00199970729396935 0.032185765017221 GO:0017124 SH3 domain binding 14/946 115/18639 0.121739130434783 2.39862119680118 0.00205789918104315 0.0326048401496523 GO:1990518 single-stranded 3'-5' DNA helicase activity 8/946 47/18639 0.170212765957447 3.35369529036031 0.00230463468696345 0.0359523011166298 GO:0005165 neurotrophin receptor binding 4/946 12/18639 0.333333333333333 6.5676532769556 0.00235142852031401 0.0361264927211879 GO:0017116 single-stranded DNA helicase activity 9/946 58/18639 0.155172413793103 3.05735583582416 0.00243720673661241 0.0368854870287311 GO:0051219 phosphoprotein binding 12/946 93/18639 0.129032258064516 2.5423173975312 0.00256688834016349 0.0382768349547908 GO:0032266 phosphatidylinositol-3-phosphate binding 8/946 48/18639 0.166666666666667 3.2838266384778 0.00264484801152258 0.0383125126240557 GO:0043138 3'-5' DNA helicase activity 8/946 48/18639 0.166666666666667 3.2838266384778 0.00264484801152258 0.0383125126240557 GO:0070063 RNA polymerase binding 9/946 59/18639 0.152542372881356 3.00553624538646 0.00274907497420367 0.0392614369555285 GO:0031994 insulin-like growth factor I binding 4/946 13/18639 0.307692307692308 6.06244917872825 0.00326109612927252 0.0446462810010394 GO:0043560 insulin receptor substrate binding 4/946 13/18639 0.307692307692308 6.06244917872825 0.00326109612927252 0.0446462810010394 GO:0000287 magnesium ion binding 22/946 230/18639 0.0956521739130435 1.88463094034378 0.00330223971901179 0.0446462810010394 GO:0005085 guanyl-nucleotide exchange factor activity 22/946 230/18639 0.0956521739130435 1.88463094034378 0.00330223971901179 0.0446462810010394 GO:0019905 syntaxin binding 9/946 61/18639 0.147540983606557 2.90699407340658 0.00346703334996756 0.0462575239061462 GO:0003779 actin binding 36/946 443/18639 0.0812641083521445 1.60114346255351 0.00375117287000507 0.0493985622101967 GO:0140789 histone phosphatase activity 15/946 136/18639 0.110294117647059 2.1731205695809 0.00382248882803804 0.0496923547644946 GO:0003678 DNA helicase activity 10/946 74/18639 0.135135135135135 2.66256213930633 0.00406663282152026 0.0513351007026086 GO:0001727 lipid kinase activity 7/946 41/18639 0.170731707317073 3.3639199711236 0.00420198556046993 0.0513351007026086 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 7/946 41/18639 0.170731707317073 3.3639199711236 0.00420198556046993 0.0513351007026086 GO:0017080 sodium channel regulator activity 7/946 41/18639 0.170731707317073 3.3639199711236 0.00420198556046993 0.0513351007026086 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/946 41/18639 0.170731707317073 3.3639199711236 0.00420198556046993 0.0513351007026086 GO:0005545 1-phosphatidylinositol binding 4/946 14/18639 0.285714285714286 5.62941709453337 0.00438385628152578 0.0529194079698469 GO:0005158 insulin receptor binding 5/946 23/18639 0.217391304347826 4.28325213714496 0.00521871663289349 0.061532310066907 GO:0044013 histone H2B acetyltransferase activity 5/946 23/18639 0.217391304347826 4.28325213714496 0.00521871663289349 0.061532310066907 GO:0003727 single-stranded RNA binding 11/946 89/18639 0.123595505617978 2.43519728246668 0.00531114851312039 0.061902351635679 GO:0035401 histone H3Y41 kinase activity 13/946 115/18639 0.11304347826087 2.22729111131538 0.00554986589640793 0.0632310563927824 GO:0140801 histone H2AXY142 kinase activity 13/946 115/18639 0.11304347826087 2.22729111131538 0.00554986589640793 0.0632310563927824 GO:0120283 protein serine/threonine kinase binding 4/946 15/18639 0.266666666666667 5.25412262156448 0.00574055060153613 0.0646768701106404 GO:0035591 signaling adaptor activity 14/946 129/18639 0.108527131782946 2.13830571807857 0.00588207803427504 0.0654881662062431 GO:0019199 transmembrane receptor protein kinase activity 10/946 78/18639 0.128205128205128 2.52602049113677 0.00594172711141456 0.0654881662062431 GO:0050699 WW domain binding 5/946 24/18639 0.208333333333333 4.10478329809725 0.00632118544610076 0.0689213122832922 GO:0016791 phosphatase activity 24/946 273/18639 0.0879120879120879 1.7321283367795 0.0064236670578013 0.0692935999639417 GO:0019903 protein phosphatase binding 15/946 144/18639 0.104166666666667 2.05239164904863 0.00649860714547785 0.0693640804791004 GO:0051539 4 iron, 4 sulfur cluster binding 7/946 45/18639 0.155555555555556 3.06490486257928 0.00711873043837901 0.0744164192218177 GO:0140303 intramembrane lipid transporter activity 7/946 45/18639 0.155555555555556 3.06490486257928 0.00711873043837901 0.0744164192218177 GO:0004708 MAP kinase kinase activity 4/946 16/18639 0.25 4.9257399577167 0.00735064167799816 0.0752883905201023 GO:0034450 ubiquitin-ubiquitin ligase activity 4/946 16/18639 0.25 4.9257399577167 0.00735064167799816 0.0752883905201023 GO:0042974 nuclear retinoic acid receptor binding 5/946 25/18639 0.2 3.94059196617336 0.0075772714286713 0.076833532286727 GO:0061631 ubiquitin conjugating enzyme activity 6/946 35/18639 0.171428571428571 3.37765025672002 0.00772020867878153 0.0775078376265789 GO:0016887 ATP hydrolysis activity 33/946 417/18639 0.079136690647482 1.55922703697507 0.00789772941054149 0.0777770393534058 GO:0032182 ubiquitin-like protein binding 13/946 120/18639 0.108333333333333 2.13448731501057 0.00790042904674634 0.0777770393534058 GO:0000993 RNA polymerase II complex binding 6/946 36/18639 0.166666666666667 3.2838266384778 0.00887545324258958 0.0865356691152484 GO:0061749 forked DNA-dependent helicase activity 7/946 47/18639 0.148936170212766 2.93448337906527 0.00904078605033236 0.0870176341519048 GO:0046965 nuclear retinoid X receptor binding 4/946 17/18639 0.235294117647059 4.63599054843925 0.00923205517068836 0.0870176341519048 GO:1990226 histone methyltransferase binding 4/946 17/18639 0.235294117647059 4.63599054843925 0.00923205517068836 0.0870176341519048 GO:0016779 nucleotidyltransferase activity 14/946 136/18639 0.102941176470588 2.02824586494217 0.00926815038304312 0.0870176341519048 GO:0009378 four-way junction helicase activity 7/946 48/18639 0.145833333333333 2.87334830866808 0.0101327754715925 0.0925642732269806 GO:0036121 double-stranded DNA helicase activity 7/946 48/18639 0.145833333333333 2.87334830866808 0.0101327754715925 0.0925642732269806 GO:0140693 molecular condensate scaffold activity 7/946 48/18639 0.145833333333333 2.87334830866808 0.0101327754715925 0.0925642732269806 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/946 60/18639 0.133333333333333 2.62706131078224 0.0105265254633245 0.0950294952460415 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/946 27/18639 0.185185185185185 3.64869626497533 0.0105900719554267 0.0950294952460415 GO:0004725 protein tyrosine phosphatase activity 11/946 98/18639 0.112244897959184 2.21155671570954 0.0108168266357521 0.0962128263916895 GO:0001222 transcription corepressor binding 7/946 49/18639 0.142857142857143 2.81470854726669 0.0113177296207791 0.0997928507432171 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.100197422514754 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.100197422514754 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.100197422514754 GO:0042975 peroxisome proliferator activated receptor binding 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.100197422514754 GO:0050815 phosphoserine residue binding 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.100197422514754 GO:0099122 RNA polymerase II C-terminal domain binding 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.100197422514754 GO:0045499 chemorepellent activity 5/946 28/18639 0.178571428571429 3.51838568408336 0.0123656291021187 0.101118934754422 GO:0046875 ephrin receptor binding 5/946 28/18639 0.178571428571429 3.51838568408336 0.0123656291021187 0.101118934754422 GO:0046966 nuclear thyroid hormone receptor binding 5/946 28/18639 0.178571428571429 3.51838568408336 0.0123656291021187 0.101118934754422 GO:0031490 chromatin DNA binding 13/946 128/18639 0.1015625 2.00108185782241 0.0132194950177704 0.107236543584153 GO:0001221 transcription coregulator binding 12/946 115/18639 0.104347826086957 2.05596102582958 0.0138506644699278 0.110759147446485 GO:0005520 insulin-like growth factor binding 4/946 19/18639 0.210526315789474 4.14799154334038 0.0138722009129227 0.110759147446485 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/946 89/18639 0.112359550561798 2.21381571133335 0.0146185877690357 0.114908899207769 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/946 89/18639 0.112359550561798 2.21381571133335 0.0146185877690357 0.114908899207769 GO:0030331 nuclear estrogen receptor binding 6/946 40/18639 0.15 2.95544397463002 0.014741620344155 0.114984638684409 GO:0019208 phosphatase regulator activity 12/946 117/18639 0.102564102564103 2.02081639290942 0.0157142640127909 0.115463739197806 GO:0140793 histone H2AXY142 phosphatase activity 10/946 90/18639 0.111111111111111 2.1892177589852 0.015723313072632 0.115463739197806 GO:0002162 dystroglycan binding 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0032050 clathrin heavy chain binding 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0034056 estrogen response element binding 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0043522 leucine zipper domain binding 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0047676 arachidonate-CoA ligase activity 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0097493 structural molecule activity conferring elasticity 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.115463739197806 GO:0034212 protein N-acetyltransferase activity 7/946 53/18639 0.132075471698113 2.60227771351071 0.0170694469604182 0.123631565841886 GO:0043021 ribonucleoprotein complex binding 16/946 177/18639 0.0903954802259887 1.78105851578457 0.0183092690766312 0.129294370826052 GO:0046332 SMAD binding 9/946 79/18639 0.113924050632911 2.24464099338989 0.0183913176680032 0.129294370826052 GO:0035198 miRNA binding 6/946 42/18639 0.142857142857143 2.81470854726669 0.0185021486930491 0.129294370826052 GO:0043175 RNA polymerase core enzyme binding 6/946 42/18639 0.142857142857143 2.81470854726669 0.0185021486930491 0.129294370826052 GO:0042578 phosphoric ester hydrolase activity 28/946 363/18639 0.0771349862258953 1.51978753516328 0.0185518667467981 0.129294370826052 GO:0008013 beta-catenin binding 11/946 106/18639 0.10377358490566 2.04464677490127 0.0186787470803018 0.129294370826052 GO:0003925 G protein activity 7/946 54/18639 0.12962962962963 2.55408738548273 0.0187801116067145 0.129294370826052 GO:0016878 acid-thiol ligase activity 5/946 31/18639 0.161290322580645 3.177896746914 0.01887136773398 0.129294370826052 GO:0051010 microtubule plus-end binding 4/946 21/18639 0.19047619047619 3.75294472968892 0.0197700608602242 0.134542561827298 GO:0005078 MAP-kinase scaffold activity 3/946 12/18639 0.25 4.9257399577167 0.0203200165924989 0.134669913887542 GO:0017166 vinculin binding 3/946 12/18639 0.25 4.9257399577167 0.0203200165924989 0.134669913887542 GO:0035497 cAMP response element binding 3/946 12/18639 0.25 4.9257399577167 0.0203200165924989 0.134669913887542 GO:0097677 STAT family protein binding 3/946 12/18639 0.25 4.9257399577167 0.0203200165924989 0.134669913887542 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/946 43/18639 0.13953488372093 2.74925020895816 0.0206078025757096 0.135690336440062 GO:0031683 G-protein beta/gamma-subunit complex binding 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0032931 histone H3K56 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0043992 histone H3K9 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0043993 histone H3K18 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0043994 histone H3K23 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0043999 histone H2AK5 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0044012 histone H2AK9 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0044014 histone H2BK5 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0044015 histone H2BK12 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0044016 histone H3K4 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0044017 histone H3K27 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0044018 histone H3K36 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0046972 histone H4K16 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0050321 tau-protein kinase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0140908 histone H3K122 acetyltransferase activity 4/946 22/18639 0.181818181818182 3.58235633288487 0.0232168533035602 0.139301119821361 GO:0030165 PDZ domain binding 9/946 83/18639 0.108433734939759 2.13646552382893 0.0245963248506127 0.146709843520713 GO:1902936 phosphatidylinositol bisphosphate binding 11/946 111/18639 0.0990990990990991 1.95254556882464 0.0253756563254667 0.149097227917383 GO:0004535 poly(A)-specific ribonuclease activity 3/946 13/18639 0.230769230769231 4.54683688404619 0.0254376927314668 0.149097227917383 GO:0046975 histone H3K36 methyltransferase activity 3/946 13/18639 0.230769230769231 4.54683688404619 0.0254376927314668 0.149097227917383 GO:0004386 helicase activity 14/946 155/18639 0.0903225806451613 1.77962217827184 0.0263156454868679 0.153356692664851 GO:0061980 regulatory RNA binding 7/946 58/18639 0.120689655172414 2.37794342786324 0.0268231326117059 0.153842796594505 GO:0042393 histone binding 20/946 247/18639 0.0809716599190283 1.59538136282322 0.0269574708280656 0.153842796594505 GO:0003887 DNA-directed DNA polymerase activity 4/946 23/18639 0.173913043478261 3.42660170971597 0.0270059347079111 0.153842796594505 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/946 23/18639 0.173913043478261 3.42660170971597 0.0270059347079111 0.153842796594505 GO:0052866 phosphatidylinositol phosphate phosphatase activity 5/946 34/18639 0.147058823529412 2.89749409277453 0.0272971054740617 0.154632765087701 GO:0031593 polyubiquitin modification-dependent protein binding 7/946 59/18639 0.11864406779661 2.33763930196725 0.0291503527936843 0.164213654071088 GO:0140030 modification-dependent protein binding 15/946 173/18639 0.0867052023121387 1.70834911828325 0.030340469000489 0.166400858950957 GO:0010485 histone H4 acetyltransferase activity 5/946 35/18639 0.142857142857143 2.81470854726669 0.0305599216066084 0.166400858950957 GO:0043495 protein-membrane adaptor activity 6/946 47/18639 0.127659574468085 2.51527146777023 0.0306389427738108 0.166400858950957 GO:0061733 protein-lysine-acetyltransferase activity 6/946 47/18639 0.127659574468085 2.51527146777023 0.0306389427738108 0.166400858950957 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.166400858950957 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.166400858950957 GO:0030215 semaphorin receptor binding 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.166400858950957 GO:0035035 histone acetyltransferase binding 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.166400858950957 GO:0043998 histone H2A acetyltransferase activity 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.166400858950957 GO:0004705 JUN kinase activity 3/946 14/18639 0.214285714285714 4.22206282090003 0.0311796481269052 0.166400858950957 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/946 60/18639 0.116666666666667 2.29867864693446 0.0316101035731657 0.167814895409372 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/946 36/18639 0.138888888888889 2.7365221987315 0.0340574165040308 0.179865730911912 GO:0005178 integrin binding 14/946 161/18639 0.0869565217391304 1.71330085485798 0.0348307401015059 0.182996738149881 GO:1990782 protein tyrosine kinase binding 11/946 117/18639 0.094017094017094 1.85241502683363 0.0355241604082414 0.185677828113179 GO:0004467 long-chain fatty acid-CoA ligase activity 3/946 15/18639 0.2 3.94059196617336 0.0375394225082475 0.193788731380913 GO:0050780 dopamine receptor binding 3/946 15/18639 0.2 3.94059196617336 0.0375394225082475 0.193788731380913 GO:0005319 lipid transporter activity 15/946 178/18639 0.0842696629213483 1.66036178350001 0.0376492900217356 0.193788731380913 GO:0019209 kinase activator activity 13/946 148/18639 0.0878378378378378 1.73066539054911 0.0382336352600022 0.195802556331526 GO:0051536 iron-sulfur cluster binding 8/946 76/18639 0.105263157894737 2.07399577167019 0.0384583547916612 0.19596367717962 GO:0008094 ATP-dependent activity, acting on DNA 17/946 210/18639 0.080952380952381 1.59500151011779 0.0391950079884064 0.19871869050122 GO:0005006 epidermal growth factor receptor activity 6/946 50/18639 0.12 2.36435517970402 0.0399558644605229 0.20019930864946 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.20019930864946 GO:0005160 transforming growth factor beta receptor binding 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.20019930864946 GO:0043548 phosphatidylinositol 3-kinase binding 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.20019930864946 GO:0050681 nuclear androgen receptor binding 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.20019930864946 GO:0051540 metal cluster binding 8/946 77/18639 0.103896103896104 2.0470607616485 0.0410904404108631 0.202260711536967 GO:0005010 insulin-like growth factor receptor activity 6/946 51/18639 0.117647058823529 2.31799527421962 0.0434188931693305 0.20796842920572 GO:0005021 vascular endothelial growth factor receptor activity 6/946 51/18639 0.117647058823529 2.31799527421962 0.0434188931693305 0.20796842920572 GO:0016830 carbon-carbon lyase activity 6/946 51/18639 0.117647058823529 2.31799527421962 0.0434188931693305 0.20796842920572 GO:0044325 transmembrane transporter binding 12/946 136/18639 0.0882352941176471 1.73849645566472 0.0439628805979544 0.20796842920572 GO:0003688 DNA replication origin binding 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0004707 MAP kinase activity 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0030275 LRR domain binding 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0043023 ribosomal large subunit binding 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0070411 I-SMAD binding 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0097027 ubiquitin-protein transferase activator activity 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.20796842920572 GO:0008266 poly(U) RNA binding 4/946 27/18639 0.148148148148148 2.91895701198027 0.0456714622040798 0.211465126369575 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/946 27/18639 0.148148148148148 2.91895701198027 0.0456714622040798 0.211465126369575 GO:0032451 demethylase activity 5/946 40/18639 0.125 2.46286997885835 0.050453173526197 0.224653988909018 GO:0030295 protein kinase activator activity 12/946 139/18639 0.0863309352517986 1.70097494942735 0.0504632555140111 0.224653988909018 GO:0070851 growth factor receptor binding 12/946 139/18639 0.0863309352517986 1.70097494942735 0.0504632555140111 0.224653988909018 GO:0017046 peptide hormone binding 6/946 53/18639 0.113207547169811 2.23052375443775 0.0508932907009109 0.224653988909018 GO:0036408 histone H3K14 acetyltransferase activity 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.224653988909018 GO:0050698 proteoglycan sulfotransferase activity 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.224653988909018 GO:0051019 mitogen-activated protein kinase binding 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.224653988909018 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.224653988909018 GO:0097718 disordered domain specific binding 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.224653988909018 GO:0141052 histone H3 demethylase activity 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.224653988909018 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.224653988909018 GO:0004659 prenyltransferase activity 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.224653988909018 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.224653988909018 GO:0015278 intracellularly gated calcium channel activity 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.224653988909018 GO:0016805 dipeptidase activity 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.224653988909018 GO:0038191 neuropilin binding 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.224653988909018 GO:0016500 protein-hormone receptor activity 7/946 67/18639 0.104477611940299 2.05851819128459 0.0527352519519499 0.226582819827446 GO:0140463 chromatin-protein adaptor activity 6/946 54/18639 0.111111111111111 2.1892177589852 0.0549074380876854 0.234920431311869 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/946 41/18639 0.121951219512195 2.402799979374 0.0551621677828214 0.235018647612525 GO:1990841 promoter-specific chromatin binding 7/946 68/18639 0.102941176470588 2.02824586494217 0.056332838044506 0.239002082749494 GO:0010484 histone H3 acetyltransferase activity 4/946 29/18639 0.137931034482759 2.7176496318437 0.0571248438667933 0.23935781686334 GO:0043236 laminin binding 4/946 29/18639 0.137931034482759 2.7176496318437 0.0571248438667933 0.23935781686334 GO:0099604 ligand-gated calcium channel activity 4/946 29/18639 0.137931034482759 2.7176496318437 0.0571248438667933 0.23935781686334 GO:0019783 ubiquitin-like protein peptidase activity 11/946 127/18639 0.0866141732283465 1.70655557590185 0.0582387280183258 0.24155749454855 GO:0140097 catalytic activity, acting on DNA 24/946 336/18639 0.0714285714285714 1.40735427363334 0.0583241949132563 0.24155749454855 GO:0043022 ribosome binding 10/946 112/18639 0.0892857142857143 1.75919284204168 0.0583644833968389 0.24155749454855 GO:0008080 N-acetyltransferase activity 7/946 69/18639 0.101449275362319 1.99885099733431 0.0600790703620707 0.245141724248169 GO:0004402 histone acetyltransferase activity 5/946 42/18639 0.119047619047619 2.34559045605557 0.0601162244165744 0.245141724248169 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.245141724248169 GO:0070628 proteasome binding 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.245141724248169 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 11/946 128/18639 0.0859375 1.69322311046512 0.0609390951297599 0.247168969846306 GO:0008187 poly-pyrimidine tract binding 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0031624 ubiquitin conjugating enzyme binding 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0032452 histone demethylase activity 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0043995 histone H4K5 acetyltransferase activity 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0043996 histone H4K8 acetyltransferase activity 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0043997 histone H4K12 acetyltransferase activity 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0070566 adenylyltransferase activity 4/946 30/18639 0.133333333333333 2.62706131078224 0.0633750595275248 0.250047900237005 GO:0099106 ion channel regulator activity 13/946 160/18639 0.08125 1.60086548625793 0.0638197378935686 0.250826411721235 GO:0008200 ion channel inhibitor activity 5/946 43/18639 0.116279069767442 2.29104184079847 0.065314700974583 0.255710837020182 GO:0101005 deubiquitinase activity 10/946 115/18639 0.0869565217391304 1.71330085485798 0.0673417146903134 0.262632687292222 GO:0015245 fatty acid transmembrane transporter activity 3/946 19/18639 0.157894736842105 3.11099365750529 0.0688835220809279 0.266595005305576 GO:0140036 ubiquitin-modified protein reader activity 3/946 19/18639 0.157894736842105 3.11099365750529 0.0688835220809279 0.266595005305576 GO:0140457 protein demethylase activity 4/946 31/18639 0.129032258064516 2.5423173975312 0.0699681990524945 0.268574899175478 GO:0008017 microtubule binding 20/946 276/18639 0.072463768115942 1.42775071238165 0.0700538517526798 0.268574899175478 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/946 86/18639 0.0930232558139535 1.83283347263877 0.0701896925853073 0.268574899175478 GO:0001046 core promoter sequence-specific DNA binding 5/946 44/18639 0.113636363636364 2.23897270805305 0.0707563198727201 0.26871501255033 GO:0016248 channel inhibitor activity 5/946 44/18639 0.113636363636364 2.23897270805305 0.0707563198727201 0.26871501255033 GO:0046915 transition metal ion transmembrane transporter activity 5/946 45/18639 0.111111111111111 2.1892177589852 0.0764391902158491 0.286672035398633 GO:0141110 transporter inhibitor activity 5/946 45/18639 0.111111111111111 2.1892177589852 0.0764391902158491 0.286672035398633 GO:0043539 protein serine/threonine kinase activator activity 7/946 73/18639 0.0958904109589041 1.8893249152886 0.0765603368933006 0.286672035398633 GO:0051059 NF-kappaB binding 4/946 32/18639 0.125 2.46286997885835 0.0768982185684697 0.286672035398633 GO:0120015 sterol transfer activity 4/946 32/18639 0.125 2.46286997885835 0.0768982185684697 0.286672035398633 GO:0001786 phosphatidylserine binding 6/946 59/18639 0.101694915254237 2.00369083025764 0.0777696820306692 0.287975085023756 GO:0004722 protein serine/threonine phosphatase activity 9/946 103/18639 0.087378640776699 1.72161784929904 0.0780449546334302 0.287975085023756 GO:0030742 GTP-dependent protein binding 3/946 20/18639 0.15 2.95544397463002 0.0780997518555552 0.287975085023756 GO:0003684 damaged DNA binding 7/946 74/18639 0.0945945945945946 1.86379349751443 0.0810551917724885 0.297789726294577 GO:0001098 basal transcription machinery binding 6/946 60/18639 0.1 1.97029598308668 0.082898524081503 0.301819491581296 GO:0001099 basal RNA polymerase II transcription machinery binding 6/946 60/18639 0.1 1.97029598308668 0.082898524081503 0.301819491581296 GO:0016874 ligase activity 13/946 167/18639 0.0778443113772455 1.53376334012736 0.0830450080386407 0.301819491581296 GO:0015631 tubulin binding 26/946 385/18639 0.0675324675324675 1.33058949507152 0.0850539783029399 0.308016907139932 GO:0003725 double-stranded RNA binding 7/946 75/18639 0.0933333333333333 1.83894291754757 0.0856992461247975 0.309249236905853 GO:0016247 channel regulator activity 13/946 168/18639 0.0773809523809524 1.52463379643612 0.086060904219306 0.309453038575802 GO:0035613 RNA stem-loop binding 3/946 21/18639 0.142857142857143 2.81470854726669 0.0878213670214437 0.310579425781729 GO:0015026 coreceptor activity 6/946 61/18639 0.0983606557377049 1.93799604893772 0.0882105417515795 0.310579425781729 GO:0031419 cobalamin binding 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.310579425781729 GO:0051880 G-quadruplex DNA binding 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.310579425781729 GO:1990757 ubiquitin ligase activator activity 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.310579425781729 GO:0001784 phosphotyrosine residue binding 5/946 47/18639 0.106382978723404 2.09605955647519 0.0885181992612622 0.310579425781729 GO:0140938 histone H3 methyltransferase activity 5/946 47/18639 0.106382978723404 2.09605955647519 0.0885181992612622 0.310579425781729 GO:0141108 transporter regulator activity 13/946 170/18639 0.0764705882352941 1.50669692824276 0.0922965910317642 0.322719804504169 GO:0019888 protein phosphatase regulator activity 9/946 107/18639 0.0841121495327103 1.65725830353085 0.0937224816300008 0.326579368978766 GO:0043178 alcohol binding 8/946 92/18639 0.0869565217391304 1.71330085485798 0.0951719888432064 0.330494509202093 GO:0005496 steroid binding 9/946 108/18639 0.0833333333333333 1.6419133192389 0.0979093807973182 0.332085903977904 GO:0008093 cytoskeletal anchor activity 3/946 22/18639 0.136363636363636 2.68676724966366 0.0980220797137411 0.332085903977904 GO:0070034 telomerase RNA binding 3/946 22/18639 0.136363636363636 2.68676724966366 0.0980220797137411 0.332085903977904 GO:0140035 ubiquitin-like protein reader activity 3/946 22/18639 0.136363636363636 2.68676724966366 0.0980220797137411 0.332085903977904 GO:0140517 protein-RNA adaptor activity 3/946 22/18639 0.136363636363636 2.68676724966366 0.0980220797137411 0.332085903977904 GO:0034061 DNA polymerase activity 4/946 35/18639 0.114285714285714 2.25176683781335 0.0996335894109035 0.332085903977904 GO:0140566 histone reader activity 4/946 35/18639 0.114285714285714 2.25176683781335 0.0996335894109035 0.332085903977904 GO:0051213 dioxygenase activity 8/946 93/18639 0.0860215053763441 1.6948782650208 0.0997710558847173 0.332085903977904 GO:0005004 GPI-linked ephrin receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0005008 hepatocyte growth factor receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0005009 insulin receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0005011 macrophage colony-stimulating factor receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0005020 stem cell factor receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0008288 boss receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0036332 placental growth factor receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0038062 protein tyrosine kinase collagen receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0060175 brain-derived neurotrophic factor receptor activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.332085903977904 GO:0000099 sulfur amino acid transmembrane transporter activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0008432 JUN kinase binding 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0032404 mismatch repair complex binding 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0034713 type I transforming growth factor beta receptor binding 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0099528 G protein-coupled neurotransmitter receptor activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.332149926925541 GO:0016410 N-acyltransferase activity 8/946 94/18639 0.0851063829787234 1.67684764518015 0.104492925729041 0.332149926925541 GO:0042562 hormone binding 8/946 94/18639 0.0851063829787234 1.67684764518015 0.104492925729041 0.332149926925541 GO:0005516 calmodulin binding 15/946 207/18639 0.072463768115942 1.42775071238165 0.105551571846724 0.334466543289307 GO:0005484 SNAP receptor activity 4/946 36/18639 0.111111111111111 2.1892177589852 0.107830611024263 0.336990655917799 GO:0005007 fibroblast growth factor receptor activity 5/946 50/18639 0.1 1.97029598308668 0.108366322131112 0.336990655917799 GO:0005017 platelet-derived growth factor receptor activity 5/946 50/18639 0.1 1.97029598308668 0.108366322131112 0.336990655917799 GO:0005019 platelet-derived growth factor beta-receptor activity 5/946 50/18639 0.1 1.97029598308668 0.108366322131112 0.336990655917799 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/946 23/18639 0.130434782608696 2.56995128228697 0.108674501464616 0.336990655917799 GO:0017134 fibroblast growth factor binding 3/946 23/18639 0.130434782608696 2.56995128228697 0.108674501464616 0.336990655917799 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/946 23/18639 0.130434782608696 2.56995128228697 0.108674501464616 0.336990655917799 GO:0120013 lipid transfer activity 6/946 65/18639 0.0923076923076923 1.81873475361847 0.111252377506274 0.343932654851714 GO:0003689 DNA clamp loader activity 12/946 160/18639 0.075 1.47772198731501 0.114198376505423 0.346479397801768 GO:0016407 acetyltransferase activity 8/946 96/18639 0.0833333333333333 1.6419133192389 0.114301213109513 0.346479397801768 GO:0005030 neurotrophin receptor activity 5/946 51/18639 0.0980392156862745 1.93166272851635 0.115425825279132 0.346479397801768 GO:0030551 cyclic nucleotide binding 4/946 37/18639 0.108108108108108 2.13004971144506 0.116320010019353 0.346479397801768 GO:0033192 calmodulin-dependent protein phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0140791 histone H2AXS140 phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/946 81/18639 0.0864197530864197 1.70272492365516 0.116642543149174 0.346479397801768 GO:0005315 phosphate transmembrane transporter activity 3/946 24/18639 0.125 2.46286997885835 0.119750446736664 0.346479397801768 GO:0030552 cAMP binding 3/946 24/18639 0.125 2.46286997885835 0.119750446736664 0.346479397801768 GO:0005025 transforming growth factor beta receptor activity, type I 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0005026 transforming growth factor beta receptor activity, type II 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0016361 activin receptor activity, type I 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0016362 activin receptor activity, type II 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0017002 activin receptor activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0034452 dynactin binding 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0070008 serine-type exopeptidase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:1990817 poly(A) RNA polymerase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.346479397801768 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/946 82/18639 0.0853658536585366 1.6819599855618 0.12229949570926 0.347371676888486 GO:0033549 MAP kinase phosphatase activity 7/946 82/18639 0.0853658536585366 1.6819599855618 0.12229949570926 0.347371676888486 GO:0030159 signaling receptor complex adaptor activity 5/946 52/18639 0.0961538461538462 1.89451536835258 0.12269834112636 0.347531055592538 GO:0042054 histone methyltransferase activity 6/946 67/18639 0.0895522388059701 1.76444416395822 0.123814367814666 0.348743802677975 GO:0050840 extracellular matrix binding 6/946 67/18639 0.0895522388059701 1.76444416395822 0.123814367814666 0.348743802677975 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/946 38/18639 0.105263157894737 2.07399577167019 0.125090640456581 0.351362629980534 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 7/946 83/18639 0.0843373493975904 1.6616954074225 0.128094204754147 0.354822130956413 GO:0005003 ephrin receptor activity 5/946 53/18639 0.0943396226415094 1.85876979536479 0.130178033879011 0.354822130956413 GO:0005005 transmembrane-ephrin receptor activity 5/946 53/18639 0.0943396226415094 1.85876979536479 0.130178033879011 0.354822130956413 GO:0005544 calcium-dependent phospholipid binding 5/946 53/18639 0.0943396226415094 1.85876979536479 0.130178033879011 0.354822130956413 GO:0038064 collagen receptor activity 5/946 53/18639 0.0943396226415094 1.85876979536479 0.130178033879011 0.354822130956413 GO:0032934 sterol binding 6/946 68/18639 0.0882352941176471 1.73849645566472 0.130344838437584 0.354822130956413 GO:0003707 nuclear steroid receptor activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0008139 nuclear localization sequence binding 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0015645 fatty acid ligase activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0015662 P-type ion transporter activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0017025 TBP-class protein binding 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0019211 phosphatase activator activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0120515 fatty acid-CoA ligase activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0140358 P-type transmembrane transporter activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.354822130956413 GO:0017018 myosin phosphatase activity 7/946 84/18639 0.0833333333333333 1.6419133192389 0.134024367229851 0.361438054178373 GO:0015485 cholesterol binding 5/946 54/18639 0.0925925925925926 1.82434813248767 0.137858706918942 0.36729522430471 GO:0017154 semaphorin receptor activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.36729522430471 GO:0070123 transforming growth factor beta receptor activity, type III 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.36729522430471 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.36729522430471 GO:0097157 pre-mRNA intronic binding 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.36729522430471 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.36729522430471 GO:0140852 histone ubiquitin ligase activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.36729522430471 GO:0008143 poly(A) binding 3/946 26/18639 0.115384615384615 2.27341844202309 0.143057765286237 0.375804424780978 GO:0050750 low-density lipoprotein particle receptor binding 3/946 26/18639 0.115384615384615 2.27341844202309 0.143057765286237 0.375804424780978 GO:0070412 R-SMAD binding 3/946 26/18639 0.115384615384615 2.27341844202309 0.143057765286237 0.375804424780978 GO:0004532 RNA exonuclease activity 4/946 40/18639 0.1 1.97029598308668 0.143428315966704 0.375804424780978 GO:0098632 cell-cell adhesion mediator activity 5/946 55/18639 0.0909090909090909 1.79117816644244 0.145733833027409 0.380861099715961 GO:0008238 exopeptidase activity 8/946 102/18639 0.0784313725490196 1.54533018281308 0.14654780074569 0.382003778807532 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/946 41/18639 0.0975609756097561 1.9222399834992 0.152970602256854 0.395694364001148 GO:0042169 SH2 domain binding 4/946 41/18639 0.0975609756097561 1.9222399834992 0.152970602256854 0.395694364001148 GO:0140318 protein transporter activity 4/946 41/18639 0.0975609756097561 1.9222399834992 0.152970602256854 0.395694364001148 GO:0061775 cohesin loader activity 11/946 153/18639 0.0718954248366013 1.41655266757866 0.155160990752997 0.396135633067433 GO:0005385 zinc ion transmembrane transporter activity 3/946 27/18639 0.111111111111111 2.1892177589852 0.155231053171506 0.396135633067433 GO:0016405 CoA-ligase activity 3/946 27/18639 0.111111111111111 2.1892177589852 0.155231053171506 0.396135633067433 GO:0005161 platelet-derived growth factor receptor binding 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.396135633067433 GO:0005313 L-glutamate transmembrane transporter activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.396135633067433 GO:0019992 diacylglycerol binding 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.396135633067433 GO:0032454 histone H3K9 demethylase activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.396135633067433 GO:0061665 SUMO ligase activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.396135633067433 GO:0098821 BMP receptor activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.396135633067433 GO:0019894 kinesin binding 4/946 42/18639 0.0952380952380952 1.87647236484446 0.162744747292673 0.409486783510596 GO:0048487 beta-tubulin binding 4/946 42/18639 0.0952380952380952 1.87647236484446 0.162744747292673 0.409486783510596 GO:0019789 SUMO transferase activity 3/946 28/18639 0.107142857142857 2.11103141045001 0.167712087425558 0.418867134604719 GO:0051393 alpha-actinin binding 3/946 28/18639 0.107142857142857 2.11103141045001 0.167712087425558 0.418867134604719 GO:0051959 dynein light intermediate chain binding 3/946 28/18639 0.107142857142857 2.11103141045001 0.167712087425558 0.418867134604719 GO:0140767 enzyme-substrate adaptor activity 10/946 139/18639 0.0719424460431655 1.41747912452279 0.169044497141538 0.421157543246976 GO:0008408 3'-5' exonuclease activity 5/946 58/18639 0.0862068965517241 1.69853101990231 0.170456326358602 0.421455487676573 GO:0005245 voltage-gated calcium channel activity 4/946 43/18639 0.0930232558139535 1.83283347263877 0.172737572556067 0.421455487676573 GO:0008375 acetylglucosaminyltransferase activity 4/946 43/18639 0.0930232558139535 1.83283347263877 0.172737572556067 0.421455487676573 GO:0035064 methylated histone binding 6/946 74/18639 0.0810810810810811 1.5975372835838 0.17277526523059 0.421455487676573 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0005041 low-density lipoprotein particle receptor activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0005523 tropomyosin binding 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0010181 FMN binding 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0030553 cGMP binding 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0034483 heparan sulfate sulfotransferase activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0051371 muscle alpha-actinin binding 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0140776 protein-containing complex destabilizing activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.421455487676573 GO:0051015 actin filament binding 14/946 209/18639 0.0669856459330144 1.31981549106285 0.177158554293659 0.425684298705617 GO:0004879 nuclear receptor activity 5/946 59/18639 0.0847457627118644 1.66974235854803 0.179038423055633 0.428568534299512 GO:0140658 ATP-dependent chromatin remodeler activity 11/946 158/18639 0.069620253164557 1.37172505151604 0.179932435348998 0.428568534299512 GO:0019003 GDP binding 6/946 75/18639 0.08 1.57623678646934 0.18034709297892 0.428568534299512 GO:0003785 actin monomer binding 3/946 29/18639 0.103448275862069 2.03823722388277 0.180472153990031 0.428568534299512 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/946 29/18639 0.103448275862069 2.03823722388277 0.180472153990031 0.428568534299512 GO:0004843 cysteine-type deubiquitinase activity 8/946 108/18639 0.0740740740740741 1.45947850599013 0.182725423724576 0.430387001378058 GO:0019205 nucleobase-containing compound kinase activity 4/946 44/18639 0.0909090909090909 1.79117816644244 0.182935697824401 0.430387001378058 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/946 44/18639 0.0909090909090909 1.79117816644244 0.182935697824401 0.430387001378058 GO:0043014 alpha-tubulin binding 4/946 44/18639 0.0909090909090909 1.79117816644244 0.182935697824401 0.430387001378058 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/946 60/18639 0.0833333333333333 1.6419133192389 0.187778413871463 0.437267875710168 GO:0098531 ligand-modulated transcription factor activity 5/946 60/18639 0.0833333333333333 1.6419133192389 0.187778413871463 0.437267875710168 GO:0098631 cell adhesion mediator activity 6/946 76/18639 0.0789473684210526 1.55549682875264 0.188048975206998 0.437267875710168 GO:0140034 methylation-dependent protein binding 6/946 76/18639 0.0789473684210526 1.55549682875264 0.188048975206998 0.437267875710168 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/946 45/18639 0.0888888888888889 1.75137420718816 0.193325601005723 0.437267875710168 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/946 30/18639 0.1 1.97029598308668 0.193482942263643 0.437267875710168 GO:0031210 phosphatidylcholine binding 3/946 30/18639 0.1 1.97029598308668 0.193482942263643 0.437267875710168 GO:0033612 receptor serine/threonine kinase binding 3/946 30/18639 0.1 1.97029598308668 0.193482942263643 0.437267875710168 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/946 30/18639 0.1 1.97029598308668 0.193482942263643 0.437267875710168 GO:0098918 structural constituent of synapse 3/946 30/18639 0.1 1.97029598308668 0.193482942263643 0.437267875710168 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0005024 transforming growth factor beta receptor activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0015923 mannosidase activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0055102 lipase inhibitor activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0140327 flippase activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0140328 floppase activity 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.437267875710168 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/946 31/18639 0.0967741935483871 1.9067380481484 0.206716664750552 0.462716772752891 GO:0070273 phosphatidylinositol-4-phosphate binding 3/946 31/18639 0.0967741935483871 1.9067380481484 0.206716664750552 0.462716772752891 GO:0070325 lipoprotein particle receptor binding 3/946 31/18639 0.0967741935483871 1.9067380481484 0.206716664750552 0.462716772752891 GO:0072349 modified amino acid transmembrane transporter activity 3/946 31/18639 0.0967741935483871 1.9067380481484 0.206716664750552 0.462716772752891 GO:0008276 protein methyltransferase activity 7/946 95/18639 0.0736842105263158 1.45179704016913 0.207379801565412 0.463178675743014 GO:0008429 phosphatidylethanolamine binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.472526070249777 GO:0008569 minus-end-directed microtubule motor activity 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.472526070249777 GO:0015085 calcium ion transmembrane transporter activity 10/946 147/18639 0.0680272108843537 1.34033740346033 0.213773522252964 0.474324620491259 GO:0070717 poly-purine tract binding 3/946 32/18639 0.09375 1.84715248414376 0.220146159183181 0.487397828409924 GO:0005262 calcium channel activity 9/946 131/18639 0.0687022900763359 1.35363846166261 0.221382166626719 0.489066485750531 GO:0019887 protein kinase regulator activity 16/946 255/18639 0.0627450980392157 1.23626414625047 0.225243008196758 0.492192532224133 GO:0008237 metallopeptidase activity 12/946 184/18639 0.0652173913043478 1.28497564114349 0.225572182062257 0.492192532224133 GO:0001618 virus receptor activity 6/946 81/18639 0.0740740740740741 1.45947850599013 0.228325229968399 0.492192532224133 GO:0030971 receptor tyrosine kinase binding 6/946 81/18639 0.0740740740740741 1.45947850599013 0.228325229968399 0.492192532224133 GO:0008170 N-methyltransferase activity 7/946 98/18639 0.0714285714285714 1.40735427363334 0.229616019984099 0.492192532224133 GO:0000400 four-way junction DNA binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0004706 JUN kinase kinase kinase activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0015172 acidic amino acid transmembrane transporter activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0016854 racemase and epimerase activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0017075 syntaxin-1 binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0017128 phospholipid scramblase activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0022851 GABA-gated chloride ion channel activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0030228 lipoprotein particle receptor activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0031690 adrenergic receptor binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0034185 apolipoprotein binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0050811 GABA receptor binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:1990381 ubiquitin-specific protease binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.492192532224133 GO:0019956 chemokine binding 3/946 33/18639 0.0909090909090909 1.79117816644244 0.233744974806432 0.49481712829587 GO:0140416 transcription regulator inhibitor activity 3/946 33/18639 0.0909090909090909 1.79117816644244 0.233744974806432 0.49481712829587 GO:0140272 exogenous protein binding 6/946 82/18639 0.0731707317073171 1.4416799876244 0.236695682673068 0.498154458064805 GO:0000510 H3-H4 histone complex chaperone activity 10/946 151/18639 0.0662251655629139 1.3048317768786 0.23777786755756 0.498154458064805 GO:0140584 chromatin extrusion motor activity 10/946 151/18639 0.0662251655629139 1.3048317768786 0.23777786755756 0.498154458064805 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 10/946 151/18639 0.0662251655629139 1.3048317768786 0.23777786755756 0.498154458064805 GO:0140849 ATP-dependent H2AZ histone chaperone activity 10/946 151/18639 0.0662251655629139 1.3048317768786 0.23777786755756 0.498154458064805 GO:0008235 metalloexopeptidase activity 5/946 66/18639 0.0757575757575758 1.49264847203536 0.243084147904891 0.507893945586945 GO:0015616 DNA translocase activity 10/946 152/18639 0.0657894736842105 1.29624735729387 0.243929340730614 0.507893945586945 GO:0140674 ATP-dependent histone chaperone activity 10/946 152/18639 0.0657894736842105 1.29624735729387 0.243929340730614 0.507893945586945 GO:0004890 GABA-A receptor activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.51557631986245 GO:0030506 ankyrin binding 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.51557631986245 GO:0042800 histone H3K4 methyltransferase activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.51557631986245 GO:0046624 sphingolipid transporter activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.51557631986245 GO:0050145 nucleoside monophosphate kinase activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.51557631986245 GO:1990380 K48-linked deubiquitinase activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.51557631986245 GO:0004527 exonuclease activity 6/946 84/18639 0.0714285714285714 1.40735427363334 0.253706886903155 0.518204004014428 GO:0051117 ATPase binding 6/946 84/18639 0.0714285714285714 1.40735427363334 0.253706886903155 0.518204004014428 GO:0002020 protease binding 9/946 136/18639 0.0661764705882353 1.30387234174854 0.253991508870977 0.518204004014428 GO:0019838 growth factor binding 9/946 136/18639 0.0661764705882353 1.30387234174854 0.253991508870977 0.518204004014428 GO:0000175 3'-5'-RNA exonuclease activity 3/946 35/18639 0.0857142857142857 1.68882512836001 0.261348743276155 0.532143826670726 GO:0005548 phospholipid transporter activity 5/946 68/18639 0.0735294117647059 1.44874704638727 0.262413618249371 0.532174817809725 GO:0030145 manganese ion binding 5/946 68/18639 0.0735294117647059 1.44874704638727 0.262413618249371 0.532174817809725 GO:0000339 RNA cap binding 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.542900817579443 GO:0015095 magnesium ion transmembrane transporter activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.542900817579443 GO:0043024 ribosomal small subunit binding 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.542900817579443 GO:0052745 inositol phosphate phosphatase activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.542900817579443 GO:0002039 p53 binding 5/946 69/18639 0.072463768115942 1.42775071238165 0.272208680897796 0.545493285435504 GO:0016279 protein-lysine N-methyltransferase activity 5/946 69/18639 0.072463768115942 1.42775071238165 0.272208680897796 0.545493285435504 GO:0031625 ubiquitin protein ligase binding 18/946 302/18639 0.0596026490066225 1.17434859919074 0.274306726290635 0.546299816510525 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/946 36/18639 0.0833333333333333 1.6419133192389 0.275304937117237 0.546299816510525 GO:0016409 palmitoyltransferase activity 3/946 36/18639 0.0833333333333333 1.6419133192389 0.275304937117237 0.546299816510525 GO:0045505 dynein intermediate chain binding 3/946 36/18639 0.0833333333333333 1.6419133192389 0.275304937117237 0.546299816510525 GO:0055106 ubiquitin-protein transferase regulator activity 3/946 36/18639 0.0833333333333333 1.6419133192389 0.275304937117237 0.546299816510525 GO:0044389 ubiquitin-like protein ligase binding 19/946 322/18639 0.0590062111801242 1.16259700865363 0.281573424146494 0.554319264582507 GO:0008146 sulfotransferase activity 4/946 53/18639 0.0754716981132075 1.48701583629183 0.281720485174297 0.554319264582507 GO:0016278 lysine N-methyltransferase activity 5/946 70/18639 0.0714285714285714 1.40735427363334 0.282079625763879 0.554319264582507 GO:0016782 transferase activity, transferring sulphur-containing groups 5/946 70/18639 0.0714285714285714 1.40735427363334 0.282079625763879 0.554319264582507 GO:0097110 scaffold protein binding 5/946 70/18639 0.0714285714285714 1.40735427363334 0.282079625763879 0.554319264582507 GO:0004197 cysteine-type endopeptidase activity 6/946 88/18639 0.0681818181818182 1.34338362483183 0.288650092699427 0.56096306153895 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.56096306153895 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.56096306153895 GO:0010314 phosphatidylinositol-5-phosphate binding 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.56096306153895 GO:0061891 calcium ion sensor activity 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.56096306153895 GO:0072542 protein phosphatase activator activity 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.56096306153895 GO:0042805 actinin binding 3/946 37/18639 0.0810810810810811 1.5975372835838 0.289333018919991 0.56096306153895 GO:0019207 kinase regulator activity 17/946 287/18639 0.0592334494773519 1.16707427569594 0.290301909130405 0.561767434843952 GO:0140299 molecular sensor activity 5/946 71/18639 0.0704225352112676 1.38753238245541 0.292018274837647 0.564012439400713 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/946 54/18639 0.0740740740740741 1.45947850599013 0.293229427434726 0.565274979883672 GO:0000146 microfilament motor activity 3/946 38/18639 0.0789473684210526 1.55549682875264 0.303410937073998 0.582686913244382 GO:0005109 frizzled binding 3/946 38/18639 0.0789473684210526 1.55549682875264 0.303410937073998 0.582686913244382 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.588354369537017 GO:0061133 endopeptidase activator activity 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.588354369537017 GO:0140784 metal ion sensor activity 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.588354369537017 GO:0072341 modified amino acid binding 6/946 91/18639 0.0659340659340659 1.29909625258462 0.31548245034488 0.601314294454339 GO:0042826 histone deacetylase binding 8/946 127/18639 0.062992125984252 1.24113132792862 0.316850103420943 0.601799741364901 GO:0000217 DNA secondary structure binding 3/946 39/18639 0.0769230769230769 1.51561229468206 0.317517615019943 0.601799741364901 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/946 39/18639 0.0769230769230769 1.51561229468206 0.317517615019943 0.601799741364901 GO:0140713 histone chaperone activity 10/946 164/18639 0.0609756097560976 1.201399989687 0.321510642283183 0.608230953871545 GO:0016917 GABA receptor activity 2/946 23/18639 0.0869565217391304 1.71330085485798 0.327095896787139 0.615352948686752 GO:0043274 phospholipase binding 2/946 23/18639 0.0869565217391304 1.71330085485798 0.327095896787139 0.615352948686752 GO:0099186 structural constituent of postsynapse 2/946 23/18639 0.0869565217391304 1.71330085485798 0.327095896787139 0.615352948686752 GO:0016504 peptidase activator activity 4/946 57/18639 0.0701754385964912 1.38266384778013 0.328063996965648 0.616031283191051 GO:0004177 aminopeptidase activity 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.619292495547169 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.619292495547169 GO:0050997 quaternary ammonium group binding 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.619292495547169 GO:0017022 myosin binding 5/946 76/18639 0.0657894736842105 1.29624735729387 0.342447211401807 0.638311530076162 GO:0004622 lysophospholipase activity 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.640125401313028 GO:0070300 phosphatidic acid binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.640125401313028 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.640125401313028 GO:0140033 acetylation-dependent protein binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.640125401313028 GO:0008307 structural constituent of muscle 3/946 42/18639 0.0714285714285714 1.40735427363334 0.359814282206071 0.66457501303635 GO:0004709 MAP kinase kinase kinase activity 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.66616540538748 GO:0017056 structural constituent of nuclear pore 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.66616540538748 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.66616540538748 GO:0019707 protein-cysteine S-acyltransferase activity 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.66616540538748 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.66616540538748 GO:0120020 cholesterol transfer activity 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.66616540538748 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/946 61/18639 0.0655737704918033 1.29199736595848 0.374795501310213 0.68352992505136 GO:0042626 ATPase-coupled transmembrane transporter activity 6/946 98/18639 0.0612244897959184 1.20630366311429 0.379257078872179 0.68961433486734 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 13/946 229/18639 0.0567685589519651 1.11850863668676 0.379491912086761 0.68961433486734 GO:0005112 Notch binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.691180727442234 GO:0008157 protein phosphatase 1 binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.691180727442234 GO:0008198 ferrous iron binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.691180727442234 GO:0070006 metalloaminopeptidase activity 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.691180727442234 GO:0015179 L-amino acid transmembrane transporter activity 4/946 62/18639 0.0645161290322581 1.2711586987656 0.386457235120078 0.69603487817364 GO:0001223 transcription coactivator binding 3/946 44/18639 0.0681818181818182 1.34338362483183 0.38781401135217 0.696715155848456 GO:0005507 copper ion binding 4/946 63/18639 0.0634920634920635 1.25098157656297 0.398090528609195 0.696715155848456 GO:0000182 rDNA binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0004955 prostaglandin receptor activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0005381 iron ion transmembrane transporter activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0005522 profilin binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0008140 cAMP response element binding protein binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0008239 dipeptidyl-peptidase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0015187 glycine transmembrane transporter activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0015203 polyamine transmembrane transporter activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0019531 oxalate transmembrane transporter activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0030957 Tat protein binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0032356 oxidized DNA binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0035256 G protein-coupled glutamate receptor binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0043422 protein kinase B binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0047429 nucleoside triphosphate diphosphatase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0051864 histone H3K36 demethylase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0070097 delta-catenin binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0140999 histone H3K4 trimethyltransferase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:1905394 retromer complex binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:1990763 arrestin family protein binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.696715155848456 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 26/946 484/18639 0.0537190082644628 1.05842346198871 0.411062277146975 0.704083022005123 GO:0004180 carboxypeptidase activity 3/946 46/18639 0.0652173913043478 1.28497564114349 0.415506903433007 0.707802150292488 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/946 46/18639 0.0652173913043478 1.28497564114349 0.415506903433007 0.707802150292488 GO:0003697 single-stranded DNA binding 7/946 121/18639 0.0578512396694215 1.13984065137246 0.416976359859821 0.707802150292488 GO:0038024 cargo receptor activity 4/946 65/18639 0.0615384615384615 1.21248983574565 0.42123489306475 0.707802150292488 GO:0099095 ligand-gated monoatomic anion channel activity 3/946 47/18639 0.0638297872340425 1.25763573388512 0.429203309806946 0.707802150292488 GO:0140359 ABC-type transporter activity 3/946 47/18639 0.0638297872340425 1.25763573388512 0.429203309806946 0.707802150292488 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0003953 NAD+ nucleosidase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0004016 adenylate cyclase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0004954 prostanoid receptor activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0005225 volume-sensitive anion channel activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0008172 S-methyltransferase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0008271 secondary active sulfate transmembrane transporter activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0008503 benzodiazepine receptor activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0010854 adenylate cyclase regulator activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0016594 glycine binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0019107 myristoyltransferase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0019206 nucleoside kinase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0032794 GTPase activating protein binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0045294 alpha-catenin binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0048185 activin binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0050786 RAGE receptor binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0050998 nitric-oxide synthase binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0070697 activin receptor binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0070990 snRNP binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0140537 transcription regulator activator activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0180030 inositol phosphate kinase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.707802150292488 GO:0016829 lyase activity 11/946 200/18639 0.055 1.08366279069767 0.436352182850009 0.707802150292488 GO:0016417 S-acyltransferase activity 2/946 29/18639 0.0689655172413793 1.35882481592185 0.436966613494179 0.707802150292488 GO:0106222 lncRNA binding 2/946 29/18639 0.0689655172413793 1.35882481592185 0.436966613494179 0.707802150292488 GO:0001216 DNA-binding transcription activator activity 26/946 491/18639 0.0529531568228106 1.04333392179743 0.440392803637409 0.712214199183943 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/946 48/18639 0.0625 1.23143498942918 0.442782878290883 0.714939233418719 GO:0001968 fibronectin binding 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.721856188500733 GO:0015215 nucleotide transmembrane transporter activity 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.721856188500733 GO:0051721 protein phosphatase 2A binding 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.721856188500733 GO:0003777 microtubule motor activity 4/946 68/18639 0.0588235294117647 1.15899763710981 0.455517767340551 0.721856188500733 GO:0016763 pentosyltransferase activity 3/946 49/18639 0.0612244897959184 1.20630366311429 0.456234112035376 0.721856188500733 GO:0004300 enoyl-CoA hydratase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0004859 phospholipase inhibitor activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0005049 nuclear export signal receptor activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0005095 GTPase inhibitor activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0005247 voltage-gated chloride channel activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0005436 sodium:phosphate symporter activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0008179 adenylate cyclase binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0015166 polyol transmembrane transporter activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0016273 arginine N-methyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0016274 protein-arginine N-methyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0031543 peptidyl-proline dioxygenase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0035197 siRNA binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0035259 nuclear glucocorticoid receptor binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0070410 co-SMAD binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0070679 inositol 1,4,5 trisphosphate binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0097371 MDM2/MDM4 family protein binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:1990459 transferrin receptor binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.721856188500733 GO:0015605 organophosphate ester transmembrane transporter activity 3/946 50/18639 0.06 1.18217758985201 0.469546373457741 0.728012267104205 GO:0017147 Wnt-protein binding 2/946 31/18639 0.0645161290322581 1.2711586987656 0.471437038058141 0.729827719986191 GO:0008234 cysteine-type peptidase activity 10/946 187/18639 0.053475935828877 1.05363421555437 0.478950777506511 0.735520773275048 GO:0005048 signal sequence binding 3/946 51/18639 0.0588235294117647 1.15899763710981 0.482709857521966 0.735520773275048 GO:0005272 sodium channel activity 3/946 51/18639 0.0588235294117647 1.15899763710981 0.482709857521966 0.735520773275048 GO:0016597 amino acid binding 3/946 51/18639 0.0588235294117647 1.15899763710981 0.482709857521966 0.735520773275048 GO:0005201 extracellular matrix structural constituent 9/946 168/18639 0.0535714285714286 1.05551570522501 0.482735866812054 0.735520773275048 GO:0046943 carboxylic acid transmembrane transporter activity 10/946 188/18639 0.0531914893617021 1.0480297782376 0.485747223832109 0.735520773275048 GO:0140597 protein carrier chaperone 10/946 188/18639 0.0531914893617021 1.0480297782376 0.485747223832109 0.735520773275048 GO:0015106 bicarbonate transmembrane transporter activity 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.735520773275048 GO:0043425 bHLH transcription factor binding 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.735520773275048 GO:0071813 lipoprotein particle binding 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.735520773275048 GO:0071814 protein-lipid complex binding 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.735520773275048 GO:0140142 nucleocytoplasmic carrier activity 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.735520773275048 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0008035 high-density lipoprotein particle binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0008253 5'-nucleotidase activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0008417 fucosyltransferase activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0045159 myosin II binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0061459 L-arginine transmembrane transporter activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0070700 BMP receptor binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0071837 HMG box domain binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0140333 glycerophospholipid flippase activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0140666 annealing activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.735520773275048 GO:0005342 organic acid transmembrane transporter activity 10/946 189/18639 0.0529100529100529 1.04248464713581 0.492523279145718 0.735520773275048 GO:0140104 molecular carrier activity 13/946 249/18639 0.0522088353413655 1.02866858554726 0.498891026950836 0.743934560776688 GO:0005518 collagen binding 4/946 72/18639 0.0555555555555556 1.0946088794926 0.500101089584081 0.744643913125195 GO:0030296 protein tyrosine kinase activator activity 2/946 33/18639 0.0606060606060606 1.19411877762829 0.50460555612357 0.749150854918448 GO:0071889 14-3-3 protein binding 2/946 33/18639 0.0606060606060606 1.19411877762829 0.50460555612357 0.749150854918448 GO:0046982 protein heterodimerization activity 19/946 369/18639 0.0514905149051491 1.0145155468468 0.507974939235908 0.750128927834393 GO:0005246 calcium channel regulator activity 3/946 53/18639 0.0566037735849057 1.11526187721888 0.508555268686835 0.750128927834393 GO:0140296 general transcription initiation factor binding 3/946 53/18639 0.0566037735849057 1.11526187721888 0.508555268686835 0.750128927834393 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 3/946 53/18639 0.0566037735849057 1.11526187721888 0.508555268686835 0.750128927834393 GO:0008201 heparin binding 9/946 172/18639 0.0523255813953488 1.03096882835931 0.511242340865194 0.750128927834393 GO:0003774 cytoskeletal motor activity 8/946 153/18639 0.0522875816993464 1.03022012187539 0.517125494151336 0.750128927834393 GO:0005347 ATP transmembrane transporter activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0008474 palmitoyl-(protein) hydrolase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0008494 translation activator activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0015926 glucosidase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0016530 metallochaperone activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0034236 protein kinase A catalytic subunit binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0046030 inositol trisphosphate phosphatase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0098599 palmitoyl hydrolase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:1901612 cardiolipin binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:1990825 sequence-specific mRNA binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.750128927834393 GO:0008376 acetylgalactosaminyltransferase activity 2/946 34/18639 0.0588235294117647 1.15899763710981 0.520675438107954 0.753159620886542 GO:0008374 O-acyltransferase activity 3/946 55/18639 0.0545454545454545 1.07470689986546 0.533707482255946 0.770834590902698 GO:1901681 sulfur compound binding 14/946 275/18639 0.0509090909090909 1.00305977320776 0.534414908683035 0.770834590902698 GO:0004089 carbonate dehydratase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0004559 alpha-mannosidase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0004953 icosanoid receptor activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0008252 nucleotidase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0015116 sulfate transmembrane transporter activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0017081 chloride channel regulator activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0033130 acetylcholine receptor binding 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0042809 nuclear vitamin D receptor binding 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0061578 K63-linked deubiquitinase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.772363661913051 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/946 56/18639 0.0535714285714286 1.05551570522501 0.546007159713886 0.775421932702914 GO:0170055 lipid transmembrane transporter activity 3/946 56/18639 0.0535714285714286 1.05551570522501 0.546007159713886 0.775421932702914 GO:0004190 aspartic-type endopeptidase activity 2/946 36/18639 0.0555555555555556 1.0946088794926 0.55175028221961 0.782482218420537 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/946 57/18639 0.0526315789473684 1.0369978858351 0.558115113199899 0.790403246906003 GO:0019001 guanyl nucleotide binding 20/946 400/18639 0.05 0.98514799154334 0.560502719112144 0.790481419765989 GO:0032561 guanyl ribonucleotide binding 20/946 400/18639 0.05 0.98514799154334 0.560502719112144 0.790481419765989 GO:0000062 fatty-acyl-CoA binding 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0005159 insulin-like growth factor receptor binding 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0008296 3'-5'-DNA exonuclease activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0015562 efflux transmembrane transporter activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0022858 alanine transmembrane transporter activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.790481419765989 GO:0019213 deacetylase activity 2/946 37/18639 0.0540540540540541 1.06502485572253 0.566745554408159 0.790481419765989 GO:0070001 aspartic-type peptidase activity 2/946 37/18639 0.0540540540540541 1.06502485572253 0.566745554408159 0.790481419765989 GO:0003730 mRNA 3'-UTR binding 13/946 262/18639 0.049618320610687 0.977627777867437 0.57380575327289 0.795556810218763 GO:0033293 monocarboxylic acid binding 4/946 79/18639 0.0506329113924051 0.997618219284395 0.573936553206097 0.795556810218763 GO:0043531 ADP binding 2/946 38/18639 0.0526315789473684 1.0369978858351 0.581375255371169 0.795556810218763 GO:0015459 potassium channel regulator activity 3/946 59/18639 0.0508474576271186 1.00184541512882 0.581737305246201 0.795556810218763 GO:0036002 pre-mRNA binding 3/946 59/18639 0.0508474576271186 1.00184541512882 0.581737305246201 0.795556810218763 GO:0070888 E-box binding 3/946 59/18639 0.0508474576271186 1.00184541512882 0.581737305246201 0.795556810218763 GO:0048306 calcium-dependent protein binding 4/946 80/18639 0.05 0.98514799154334 0.583974598537031 0.795556810218763 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0005092 GDP-dissociation inhibitor activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0016018 cyclosporin A binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0019198 transmembrane receptor protein phosphatase activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0030169 low-density lipoprotein particle binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0030548 acetylcholine receptor regulator activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0032183 SUMO binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0036041 long-chain fatty acid binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0045236 CXCR chemokine receptor binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0048038 quinone binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:0070402 NADPH binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:1901567 fatty acid derivative binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.795556810218763 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 6/946 122/18639 0.0491803278688525 0.968998024468859 0.590070608069976 0.797775462110608 GO:0061135 endopeptidase regulator activity 9/946 184/18639 0.0489130434782609 0.963731730857616 0.593309295710301 0.798335064112202 GO:0015101 organic cation transmembrane transporter activity 4/946 81/18639 0.0493827160493827 0.972985670660089 0.59387438431507 0.798335064112202 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/946 39/18639 0.0512820512820513 1.01040819645471 0.595637830525289 0.798335064112202 GO:0015171 amino acid transmembrane transporter activity 5/946 102/18639 0.0490196078431373 0.965831364258177 0.595706152702569 0.798335064112202 GO:0061134 peptidase regulator activity 11/946 226/18639 0.0486725663716814 0.958993620086438 0.600286074518231 0.798335064112202 GO:0019955 cytokine binding 7/946 144/18639 0.0486111111111111 0.957782769556025 0.600739238733982 0.798335064112202 GO:0033218 amide binding 12/946 247/18639 0.048582995951417 0.957228817693934 0.60361528489302 0.798335064112202 GO:0005253 monoatomic anion channel activity 5/946 103/18639 0.0485436893203883 0.95645436072169 0.604414947960755 0.798335064112202 GO:0016836 hydro-lyase activity 3/946 61/18639 0.0491803278688525 0.968998024468859 0.604542787333201 0.798335064112202 GO:0000900 mRNA regulatory element binding translation repressor activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0003746 translation elongation factor activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0004970 glutamate-gated receptor activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0008308 voltage-gated monoatomic anion channel activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0008409 5'-3' exonuclease activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0008525 phosphatidylcholine transporter activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0015280 ligand-gated sodium channel activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0035615 clathrin adaptor activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0098641 cadherin binding involved in cell-cell adhesion 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0099602 neurotransmitter receptor regulator activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:1901611 phosphatidylglycerol binding 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.798335064112202 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/946 40/18639 0.05 0.98514799154334 0.609532823521787 0.798535249420015 GO:0008514 organic anion transmembrane transporter activity 13/946 269/18639 0.0483271375464684 0.952187649818842 0.612239652794172 0.800734267635905 GO:0031406 carboxylic acid binding 9/946 187/18639 0.0481283422459893 0.948270793998937 0.612790721583296 0.800734267635905 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 8/946 167/18639 0.0479041916167665 0.943854363155296 0.617145463438141 0.805386743791859 GO:0043177 organic acid binding 9/946 189/18639 0.0476190476190476 0.938236182422229 0.625511138698185 0.806678478264678 GO:0022824 transmitter-gated monoatomic ion channel activity 3/946 63/18639 0.0476190476190476 0.938236182422229 0.626508950938406 0.806678478264678 GO:0022835 transmitter-gated channel activity 3/946 63/18639 0.0476190476190476 0.938236182422229 0.626508950938406 0.806678478264678 GO:1901682 sulfur compound transmembrane transporter activity 3/946 63/18639 0.0476190476190476 0.938236182422229 0.626508950938406 0.806678478264678 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0005229 intracellularly calcium-gated chloride channel activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0008381 mechanosensitive monoatomic ion channel activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0008574 plus-end-directed microtubule motor activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0043395 heparan sulfate proteoglycan binding 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0070003 threonine-type peptidase activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0120227 acyl-CoA binding 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0141147 intracellularly calcium-gated channel activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.806678478264678 GO:0004520 DNA endonuclease activity 2/946 42/18639 0.0476190476190476 0.938236182422229 0.636223093331162 0.81558813734235 GO:0019842 vitamin binding 7/946 150/18639 0.0466666666666667 0.919471458773784 0.643620341430043 0.820859566213805 GO:0005525 GTP binding 18/946 378/18639 0.0476190476190476 0.938236182422229 0.64418275202244 0.820859566213805 GO:0010851 cyclase regulator activity 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.820859566213805 GO:0016505 peptidase activator activity involved in apoptotic process 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.820859566213805 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.820859566213805 GO:0031418 L-ascorbic acid binding 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.820859566213805 GO:0061608 nuclear import signal receptor activity 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.820859566213805 GO:0140939 histone H4 methyltransferase activity 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.820859566213805 GO:0160215 deacylase activity 3/946 65/18639 0.0461538461538462 0.909367376809237 0.647620959537518 0.820859566213805 GO:0008081 phosphoric diester hydrolase activity 4/946 87/18639 0.0459770114942529 0.905883210614566 0.650231637652324 0.823139676129159 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/946 130/18639 0.0461538461538462 0.909367376809237 0.651756525709838 0.824041293104458 GO:0016790 thiolester hydrolase activity 2/946 44/18639 0.0454545454545455 0.895589083221219 0.661460499729301 0.831792771477766 GO:0004222 metalloendopeptidase activity 5/946 110/18639 0.0454545454545455 0.895589083221219 0.662250594369849 0.831792771477766 GO:0001846 opsonin binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0005248 voltage-gated sodium channel activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0009975 cyclase activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0015174 basic amino acid transmembrane transporter activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0036122 BMP binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0140312 cargo adaptor activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.831792771477766 GO:0005200 structural constituent of cytoskeleton 5/946 112/18639 0.0446428571428571 0.87959642102084 0.677727106145998 0.846324243389214 GO:0004407 histone deacetylase activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.847830909108435 GO:0008649 rRNA methyltransferase activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.847830909108435 GO:0008970 phospholipase A1 activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.847830909108435 GO:0033558 protein lysine deacetylase activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.847830909108435 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/946 91/18639 0.043956043956044 0.86606416838975 0.684784004495175 0.849903280976875 GO:0098960 postsynaptic neurotransmitter receptor activity 3/946 69/18639 0.0434782608695652 0.856650427428992 0.687256970600605 0.851929789962119 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/946 70/18639 0.0428571428571429 0.844412564180006 0.696626981256818 0.854283104660871 GO:0005504 fatty acid binding 2/946 47/18639 0.0425531914893617 0.838423822590077 0.696651760287207 0.854283104660871 GO:0000295 adenine nucleotide transmembrane transporter activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0005283 amino acid:sodium symporter activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0008171 O-methyltransferase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0016493 C-C chemokine receptor activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0016849 phosphorus-oxygen lyase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0031681 G-protein beta-subunit binding 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0070577 lysine-acetylated histone binding 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0140102 catalytic activity, acting on a rRNA 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0140103 catalytic activity, acting on a glycoprotein 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.854283104660871 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/946 48/18639 0.0416666666666667 0.82095665961945 0.707689537765308 0.858744297551011 GO:0038187 pattern recognition receptor activity 2/946 48/18639 0.0416666666666667 0.82095665961945 0.707689537765308 0.858744297551011 GO:0003924 GTPase activity 15/946 331/18639 0.0453172205438066 0.892883376021154 0.710987413084944 0.858744297551011 GO:0008168 methyltransferase activity 9/946 204/18639 0.0441176470588235 0.869248227832359 0.713337241260183 0.858744297551011 GO:0015295 solute:proton symporter activity 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0019957 C-C chemokine binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0048027 mRNA 5'-UTR binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0050431 transforming growth factor beta binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0070840 dynein complex binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0140612 DNA damage sensor activity 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.858744297551011 GO:0140101 catalytic activity, acting on a tRNA 6/946 139/18639 0.0431654676258993 0.850487474713675 0.713926472224361 0.858744297551011 GO:0004866 endopeptidase inhibitor activity 7/946 161/18639 0.0434782608695652 0.856650427428992 0.714815938793701 0.858795452531769 GO:0004867 serine-type endopeptidase inhibitor activity 4/946 95/18639 0.0421052631578947 0.829598308668076 0.716861507786893 0.860233809344272 GO:0035254 glutamate receptor binding 2/946 49/18639 0.0408163265306122 0.804202442076196 0.718389768647433 0.861048729797278 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/946 73/18639 0.0410958904109589 0.809710677980828 0.723456441873965 0.863732301170771 GO:0004896 cytokine receptor activity 4/946 96/18639 0.0416666666666667 0.82095665961945 0.724493870910969 0.863732301170771 GO:0000030 mannosyltransferase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0005251 delayed rectifier potassium channel activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0005537 D-mannose binding 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0008483 transaminase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0015271 outward rectifier potassium channel activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0047617 fatty acyl-CoA hydrolase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.863732301170771 GO:0030594 neurotransmitter receptor activity 4/946 97/18639 0.0412371134020619 0.812493188901724 0.731972201394953 0.864934505112815 GO:0031491 nucleosome binding 3/946 74/18639 0.0405405405405405 0.798768641791898 0.731977448980725 0.864934505112815 GO:0048029 monosaccharide binding 3/946 74/18639 0.0405405405405405 0.798768641791898 0.731977448980725 0.864934505112815 GO:0015103 inorganic anion transmembrane transporter activity 7/946 165/18639 0.0424242424242424 0.835883144339804 0.738181869482231 0.864934505112815 GO:0004518 nuclease activity 9/946 209/18639 0.0430622009569378 0.84845281568326 0.739421796147558 0.864934505112815 GO:0004540 RNA nuclease activity 5/946 121/18639 0.0413223140495868 0.814171893837471 0.741388444160309 0.864934505112815 GO:0001637 G protein-coupled chemoattractant receptor activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0004529 DNA exonuclease activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0004950 chemokine receptor activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0005227 calcium-activated cation channel activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0008066 glutamate receptor activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0015216 purine nucleotide transmembrane transporter activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0016289 acyl-CoA hydrolase activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0030247 polysaccharide binding 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.864934505112815 GO:0001664 G protein-coupled receptor binding 13/946 297/18639 0.0437710437710438 0.862419117175988 0.747023338924127 0.869668961732566 GO:0005080 protein kinase C binding 2/946 52/18639 0.0384615384615385 0.757806147341031 0.748524453539232 0.870380634139597 GO:0004175 endopeptidase activity 18/946 405/18639 0.0444444444444444 0.87568710359408 0.752510839630231 0.870380634139597 GO:0005044 scavenger receptor activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.870380634139597 GO:0005104 fibroblast growth factor receptor binding 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.870380634139597 GO:0008320 protein transmembrane transporter activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.870380634139597 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.870380634139597 GO:0035255 ionotropic glutamate receptor binding 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.870380634139597 GO:0003724 RNA helicase activity 3/946 77/18639 0.038961038961039 0.767647785618187 0.756299993061581 0.870380634139597 GO:0001217 DNA-binding transcription repressor activity 12/946 278/18639 0.0431654676258993 0.850487474713675 0.757689738101952 0.870380634139597 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.870380634139597 GO:0051018 protein kinase A binding 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.870380634139597 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.870380634139597 GO:0030414 peptidase inhibitor activity 7/946 169/18639 0.0414201183431953 0.816098927905726 0.760176842048531 0.871967554114491 GO:0140098 catalytic activity, acting on RNA 17/946 387/18639 0.0439276485788114 0.865504695412754 0.764178502304729 0.875567233149147 GO:0050661 NADP binding 2/946 54/18639 0.037037037037037 0.729739252995067 0.767039375775842 0.877565061305877 GO:0051537 2 iron, 2 sulfur cluster binding 1/946 28/18639 0.0357142857142857 0.703677136816672 0.76765306644804 0.877565061305877 GO:0016741 transferase activity, transferring one-carbon groups 9/946 215/18639 0.0418604651162791 0.824775062687448 0.768533117744928 0.87758173580333 GO:0008186 ATP-dependent activity, acting on RNA 3/946 79/18639 0.0379746835443038 0.748213664463297 0.77150402016489 0.8789944679182 GO:0016835 carbon-oxygen lyase activity 3/946 79/18639 0.0379746835443038 0.748213664463297 0.77150402016489 0.8789944679182 GO:0008509 monoatomic anion transmembrane transporter activity 6/946 149/18639 0.0402684563758389 0.793407778424167 0.773533126658745 0.879838695906334 GO:0008236 serine-type peptidase activity 8/946 194/18639 0.0412371134020619 0.812493188901724 0.773980391270661 0.879838695906334 GO:0004181 metallocarboxypeptidase activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.884089242804729 GO:0005416 amino acid:monoatomic cation symporter activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.884089242804729 GO:0016758 hexosyltransferase activity 8/946 197/18639 0.0406091370558376 0.800120196177332 0.788091442909098 0.89082583032438 GO:0005539 glycosaminoglycan binding 10/946 242/18639 0.0413223140495868 0.814171893837471 0.790072953268697 0.89082583032438 GO:0001965 G-protein alpha-subunit binding 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.89082583032438 GO:0016769 transferase activity, transferring nitrogenous groups 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.89082583032438 GO:0022839 monoatomic ion-gated channel activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.89082583032438 GO:0048019 receptor antagonist activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.89082583032438 GO:0017171 serine hydrolase activity 8/946 198/18639 0.0404040404040404 0.796079185085528 0.79264758160211 0.892058432568856 GO:0015291 secondary active transmembrane transporter activity 12/946 287/18639 0.0418118466898955 0.823817135785372 0.793730495682139 0.892286832174821 GO:0005254 chloride channel activity 3/946 83/18639 0.036144578313253 0.712155174609644 0.799580601973618 0.896016256400684 GO:0008135 translation factor activity, RNA binding 3/946 83/18639 0.036144578313253 0.712155174609644 0.799580601973618 0.896016256400684 GO:0005452 solute:inorganic anion antiporter activity 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.896016256400684 GO:0047499 calcium-independent phospholipase A2 activity 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.896016256400684 GO:0016757 glycosyltransferase activity 11/946 267/18639 0.0411985018726592 0.811732427488895 0.801466217510277 0.896016256400684 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 11/946 268/18639 0.041044776119403 0.808703575147518 0.805256794289456 0.899248541628807 GO:0180051 translation factor activity 3/946 84/18639 0.0357142857142857 0.703677136816672 0.80613108909328 0.899248541628807 GO:0022884 macromolecule transmembrane transporter activity 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.902166312609188 GO:0031369 translation initiation factor binding 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.902166312609188 GO:0047498 calcium-dependent phospholipase A2 activity 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.902166312609188 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/946 60/18639 0.0333333333333333 0.65676532769556 0.81562190943389 0.90584952482581 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/946 181/18639 0.0386740331491713 0.761992921635733 0.818053003418333 0.907271241818338 GO:0050660 flavin adenine dinucleotide binding 3/946 86/18639 0.0348837209302326 0.68731255223954 0.818691505191104 0.907271241818338 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/946 33/18639 0.0303030303030303 0.597059388814146 0.821003676971672 0.907849213139886 GO:0140311 protein sequestering activity 1/946 33/18639 0.0303030303030303 0.597059388814146 0.821003676971672 0.907849213139886 GO:0099094 ligand-gated monoatomic cation channel activity 5/946 136/18639 0.0367647058823529 0.724373523193633 0.826064794711188 0.912450655596018 GO:0015020 glucuronosyltransferase activity 1/946 34/18639 0.0294117647058824 0.579498818554906 0.830104532694815 0.914919561035373 GO:0016831 carboxy-lyase activity 1/946 34/18639 0.0294117647058824 0.579498818554906 0.830104532694815 0.914919561035373 GO:0015276 ligand-gated monoatomic ion channel activity 7/946 186/18639 0.0376344086021505 0.7415092409466 0.838711819294336 0.920438889958697 GO:0004623 phospholipase A2 activity 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.920438889958697 GO:0005343 organic acid:sodium symporter activity 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.920438889958697 GO:0043015 gamma-tubulin binding 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.920438889958697 GO:0004536 DNA nuclease activity 2/946 64/18639 0.03125 0.615717494714588 0.84276825767872 0.922449116139801 GO:0015294 solute:monoatomic cation symporter activity 4/946 116/18639 0.0344827586206897 0.679412407960924 0.84633100598447 0.922449116139801 GO:0022834 ligand-gated channel activity 7/946 188/18639 0.0372340425531915 0.733620844766317 0.846434483497696 0.922449116139801 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/946 36/18639 0.0277777777777778 0.5473044397463 0.846942926159916 0.922449116139801 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/946 36/18639 0.0277777777777778 0.5473044397463 0.846942926159916 0.922449116139801 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/946 36/18639 0.0277777777777778 0.5473044397463 0.846942926159916 0.922449116139801 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/946 36/18639 0.0277777777777778 0.5473044397463 0.846942926159916 0.922449116139801 GO:0019843 rRNA binding 2/946 65/18639 0.0307692307692308 0.606244917872825 0.848963410000663 0.923657615601579 GO:0052689 carboxylic ester hydrolase activity 3/946 92/18639 0.0326086956521739 0.642487820571744 0.852285709560879 0.92574956828955 GO:0015399 primary active transmembrane transporter activity 6/946 166/18639 0.036144578313253 0.712155174609644 0.852712127004378 0.92574956828955 GO:0043394 proteoglycan binding 1/946 37/18639 0.027027027027027 0.532512427861265 0.854726186486353 0.926853100417676 GO:0022853 active monoatomic ion transmembrane transporter activity 4/946 118/18639 0.0338983050847458 0.667896943419214 0.855556708077854 0.926853100417676 GO:0022843 voltage-gated monoatomic cation channel activity 5/946 143/18639 0.034965034965035 0.688914679400937 0.857103573490615 0.927537911973836 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/946 67/18639 0.0298507462686567 0.588148054652741 0.860691417506978 0.929982602321616 GO:0042162 telomeric DNA binding 1/946 38/18639 0.0263157894736842 0.518498942917548 0.862114049489466 0.929982602321616 GO:0042887 amide transmembrane transporter activity 1/946 38/18639 0.0263157894736842 0.518498942917548 0.862114049489466 0.929982602321616 GO:0008194 UDP-glycosyltransferase activity 5/946 145/18639 0.0344827586206897 0.679412407960924 0.865074092310513 0.93218398470017 GO:0140223 general transcription initiation factor activity 2/946 68/18639 0.0294117647058824 0.579498818554906 0.866237466153804 0.932446699235623 GO:0015108 chloride transmembrane transporter activity 4/946 121/18639 0.0330578512396694 0.651337515069977 0.868509485440036 0.932586617681921 GO:0015293 symporter activity 5/946 146/18639 0.0342465753424658 0.674758898317356 0.868917112796294 0.932586617681921 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/946 39/18639 0.0256410256410256 0.505204098227354 0.869126581567471 0.932586617681921 GO:0061791 GTPase motor activity 1/946 40/18639 0.025 0.49257399577167 0.875782831773771 0.936755054239033 GO:0071949 FAD binding 1/946 40/18639 0.025 0.49257399577167 0.875782831773771 0.936755054239033 GO:1990606 membrane scission GTPase motor activity 1/946 40/18639 0.025 0.49257399577167 0.875782831773771 0.936755054239033 GO:0005244 voltage-gated monoatomic ion channel activity 6/946 173/18639 0.0346820809248555 0.6833396473133 0.877968437444213 0.937578926320885 GO:0046873 metal ion transmembrane transporter activity 18/946 450/18639 0.04 0.788118393234672 0.879908364333063 0.937578926320885 GO:0005267 potassium channel activity 4/946 124/18639 0.032258064516129 0.6355793493828 0.880450987326093 0.937578926320885 GO:0001530 lipopolysaccharide binding 1/946 41/18639 0.024390243902439 0.4805599958748 0.882100883343318 0.937578926320885 GO:0004812 aminoacyl-tRNA ligase activity 1/946 41/18639 0.024390243902439 0.4805599958748 0.882100883343318 0.937578926320885 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/946 41/18639 0.024390243902439 0.4805599958748 0.882100883343318 0.937578926320885 GO:0022832 voltage-gated channel activity 6/946 175/18639 0.0342857142857143 0.675530051344005 0.88448011081056 0.939031567516657 GO:0016859 cis-trans isomerase activity 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.939031567516657 GO:0031492 nucleosomal DNA binding 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.939031567516657 GO:0042056 chemoattractant activity 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.939031567516657 GO:0051879 Hsp90 protein binding 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.939031567516657 GO:0042277 peptide binding 9/946 249/18639 0.036144578313253 0.712155174609644 0.890331836037047 0.940413001814131 GO:0004519 endonuclease activity 4/946 127/18639 0.031496062992126 0.620565663964309 0.891439583026649 0.940603264504706 GO:0022804 active transmembrane transporter activity 18/946 457/18639 0.0393873085339169 0.776046557889721 0.894013057485066 0.942338087619394 GO:0005126 cytokine receptor binding 10/946 275/18639 0.0363636363636364 0.716471266576975 0.896416668760847 0.943890448726375 GO:0030547 signaling receptor inhibitor activity 1/946 44/18639 0.0227272727272727 0.447794541610609 0.899193201407399 0.945158221355124 GO:0016853 isomerase activity 6/946 180/18639 0.0333333333333333 0.65676532769556 0.899484895076622 0.945158221355124 GO:0004857 enzyme inhibitor activity 16/946 416/18639 0.0384615384615385 0.757806147341031 0.901917130496074 0.946732888533147 GO:0031072 heat shock protein binding 4/946 131/18639 0.0305343511450382 0.601617094072269 0.904708911814508 0.948681320144685 GO:0015370 solute:sodium symporter activity 2/946 79/18639 0.0253164556962025 0.498809109642198 0.915154116415153 0.958642845087774 GO:0015297 antiporter activity 4/946 135/18639 0.0296296296296296 0.583791402396054 0.916522050087232 0.959084993589735 GO:0000049 tRNA binding 2/946 80/18639 0.025 0.49257399577167 0.918650110136894 0.960320836782279 GO:0015081 sodium ion transmembrane transporter activity 5/946 164/18639 0.0304878048780488 0.6006999948435 0.923711834184134 0.964617713555831 GO:0001540 amyloid-beta binding 2/946 83/18639 0.0240963855421687 0.474770116406429 0.928342083957136 0.968254586910581 GO:0003743 translation initiation factor activity 1/946 51/18639 0.0196078431372549 0.386332545703271 0.930059139695174 0.968254586910581 GO:0030544 Hsp70 protein binding 1/946 51/18639 0.0196078431372549 0.386332545703271 0.930059139695174 0.968254586910581 GO:0022836 gated channel activity 11/946 318/18639 0.0345911949685535 0.681548924967091 0.9339525227718 0.971310623682672 GO:0004864 protein phosphatase inhibitor activity 1/946 53/18639 0.0188679245283019 0.371753959072959 0.93699717475947 0.9734786221374 GO:0009055 electron transfer activity 3/946 116/18639 0.0258620689655172 0.509559305970693 0.938127424792891 0.973655280184229 GO:0051287 NAD binding 1/946 54/18639 0.0185185185185185 0.364869626497533 0.940203925683689 0.974812659144438 GO:0140313 molecular sequestering activity 1/946 55/18639 0.0181818181818182 0.358235633288487 0.943247621476169 0.976969446554479 GO:0019212 phosphatase inhibitor activity 1/946 56/18639 0.0178571428571429 0.351838568408336 0.946136544747991 0.977963767965813 GO:0030170 pyridoxal phosphate binding 1/946 56/18639 0.0178571428571429 0.351838568408336 0.946136544747991 0.977963767965813 GO:0004252 serine-type endopeptidase activity 5/946 176/18639 0.0284090909090909 0.559743177013261 0.947887424487972 0.978775813065992 GO:0070279 vitamin B6 binding 1/946 57/18639 0.0175438596491228 0.345665961945032 0.948878557806614 0.978802500117911 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/946 58/18639 0.0172413793103448 0.339706203980462 0.951481123962838 0.980489694815363 GO:0005506 iron ion binding 4/946 154/18639 0.025974025974026 0.511765190412125 0.956559523162085 0.984722189326248 GO:0140375 immune receptor activity 4/946 156/18639 0.0256410256410256 0.505204098227354 0.959533162091177 0.98678156831689 GO:0005249 voltage-gated potassium channel activity 2/946 98/18639 0.0204081632653061 0.402101221038098 0.962471269666188 0.987854591728475 GO:0005261 monoatomic cation channel activity 11/946 341/18639 0.032258064516129 0.6355793493828 0.96252498681236 0.987854591728475 GO:0015079 potassium ion transmembrane transporter activity 4/946 160/18639 0.025 0.49257399577167 0.964923220700719 0.989314606461607 GO:0008083 growth factor activity 4/946 162/18639 0.0246913580246914 0.486492835330045 0.967360615613945 0.990811782053071 GO:0051087 protein-folding chaperone binding 3/946 134/18639 0.0223880597014925 0.441111040989555 0.969114518677729 0.991192577106937 GO:0008173 RNA methyltransferase activity 1/946 67/18639 0.0149253731343284 0.29407402732637 0.969687412712112 0.991192577106937 GO:0030246 carbohydrate binding 8/946 280/18639 0.0285714285714286 0.562941709453337 0.975482085987618 0.995521936490994 GO:0042379 chemokine receptor binding 1/946 72/18639 0.0138888888888889 0.27365221987315 0.976660803103577 0.995521936490994 GO:0004620 phospholipase activity 2/946 109/18639 0.018348623853211 0.361522198731501 0.976906175542189 0.995521936490994 GO:0004521 RNA endonuclease activity 1/946 73/18639 0.0136986301369863 0.269903559326943 0.977849949452692 0.995521936490994 GO:0005216 monoatomic ion channel activity 14/946 448/18639 0.03125 0.615717494714588 0.98351900904354 0.999717224885755 GO:0015078 proton transmembrane transporter activity 4/946 185/18639 0.0216216216216216 0.426009942289012 0.986079529192877 0.999717224885755 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/946 122/18639 0.0163934426229508 0.32299934148962 0.98711858158789 0.999717224885755 GO:0004860 protein kinase inhibitor activity 1/946 84/18639 0.0119047619047619 0.234559045605557 0.987541413881752 0.999717224885755 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/946 88/18639 0.0113636363636364 0.223897270805305 0.989894538492561 0.999717224885755 GO:0019210 kinase inhibitor activity 1/946 90/18639 0.0111111111111111 0.21892177589852 0.990898933198779 0.999717224885755 GO:0016298 lipase activity 2/946 130/18639 0.0153846153846154 0.303122458936412 0.991047469226214 0.999717224885755 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/946 130/18639 0.0153846153846154 0.303122458936412 0.991047469226214 0.999717224885755 GO:0005179 hormone activity 2/946 132/18639 0.0151515151515152 0.298529694407073 0.991829909502041 0.999717224885755 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/946 132/18639 0.0151515151515152 0.298529694407073 0.991829909502041 0.999717224885755 GO:0046906 tetrapyrrole binding 2/946 152/18639 0.0131578947368421 0.259249471458774 0.99675766439515 0.999999415750326 GO:0051082 unfolded protein binding 1/946 121/18639 0.00826446280991736 0.162834378767494 0.998206264617131 0.999999415750326 GO:0008528 G protein-coupled peptide receptor activity 1/946 122/18639 0.00819672131147541 0.16149967074481 0.998297898361174 0.999999415750326 GO:0001653 peptide receptor activity 1/946 128/18639 0.0078125 0.153929373678647 0.998757427727655 0.999999415750326 GO:0003735 structural constituent of ribosome 2/946 175/18639 0.0114285714285714 0.225176683781335 0.998900189823768 0.999999415750326 GO:0045182 translation regulator activity 4/946 356/18639 0.0112359550561798 0.221381571133335 0.999989576595191 0.999999415750326 GO:0005125 cytokine activity 1/946 234/18639 0.00427350427350427 0.0842006830378923 0.999995296736235 0.999999415750326 GO:0030371 translation repressor activity 2/946 329/18639 0.0060790273556231 0.119774831798582 0.999999415750326 0.999999415750326