ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 70/768 334/18639 0.209580838323353 5.08642870508982 3.44546304297481e-30 3.24218072343929e-27 GO:0003735 structural constituent of ribosome 46/768 175/18639 0.262857142857143 6.37941964285714 1.41992021464619e-24 6.68072460991033e-22 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 20/768 68/18639 0.294117647058824 7.13809742647059 1.98095501147018e-12 6.21359555264479e-10 GO:0022853 active monoatomic ion transmembrane transporter activity 24/768 118/18639 0.203389830508475 4.93617584745763 7.12988894816561e-11 1.67730637505596e-08 GO:0004857 enzyme inhibitor activity 47/768 416/18639 0.112980769230769 2.74199030949519 3.75705149226818e-10 7.07077090844871e-08 GO:0043236 laminin binding 12/768 29/18639 0.413793103448276 10.0425646551724 5.98334256818993e-10 9.38387559444453e-08 GO:0031625 ubiquitin protein ligase binding 38/768 302/18639 0.125827814569536 3.05378207781457 9.19325260221695e-10 1.13123279120648e-07 GO:0015399 primary active transmembrane transporter activity 27/768 166/18639 0.162650602409639 3.94745387801205 9.61728196562367e-10 1.13123279120648e-07 GO:0044389 ubiquitin-like protein ligase binding 39/768 322/18639 0.12111801242236 2.93947738742236 1.67827232748733e-09 1.75472695573953e-07 GO:0015078 proton transmembrane transporter activity 28/768 185/18639 0.151351351351351 3.67322635135135 2.53514255985134e-09 2.38556914882012e-07 GO:0005518 collagen binding 17/768 72/18639 0.236111111111111 5.73030598958333 3.85850540406293e-09 3.30077598656656e-07 GO:0009055 electron transfer activity 21/768 116/18639 0.181034482758621 4.39362203663793 9.97492356206857e-09 7.8220025599221e-07 GO:0019843 rRNA binding 15/768 65/18639 0.230769230769231 5.60066105769231 4.43460124906217e-08 3.14786032355455e-06 GO:0005178 integrin binding 24/768 161/18639 0.149068322981366 3.61781832298137 4.68332035385374e-08 3.14786032355455e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 12/768 41/18639 0.292682926829268 7.10327743902439 5.77108775009987e-08 3.62039571522932e-06 GO:0003779 actin binding 44/768 443/18639 0.0993227990970655 2.4105177765237 6.74944398254456e-08 3.79042519266417e-06 GO:0050840 extracellular matrix binding 15/768 67/18639 0.223880597014925 5.43347714552239 6.84773945539754e-08 3.79042519266417e-06 GO:0005201 extracellular matrix structural constituent 24/768 168/18639 0.142857142857143 3.46707589285714 1.07162426298959e-07 5.60221350818444e-06 GO:0003954 NADH dehydrogenase activity 12/768 44/18639 0.272727272727273 6.61896306818182 1.37514903120739e-07 6.81060651771658e-06 GO:0098641 cadherin binding involved in cell-cell adhesion 8/768 18/18639 0.444444444444444 10.7864583333333 2.42800500486947e-07 1.14237635479108e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/768 58/18639 0.224137931034483 5.43972252155173 5.05510436244984e-07 2.22862710682506e-05 GO:0051015 actin filament binding 26/768 209/18639 0.124401913875598 3.01917613636364 5.21039281085562e-07 2.22862710682506e-05 GO:0031386 protein tag activity 7/768 15/18639 0.466666666666667 11.32578125 9.45161660215976e-07 3.70582134276347e-05 GO:0141047 molecular tag activity 7/768 15/18639 0.466666666666667 11.32578125 9.45161660215976e-07 3.70582134276347e-05 GO:0001968 fibronectin binding 9/768 30/18639 0.3 7.280859375 2.14255428688274e-06 8.06457433582662e-05 GO:0098631 cell adhesion mediator activity 14/768 76/18639 0.184210526315789 4.470703125 2.31260919847141e-06 8.36986636831384e-05 GO:0005200 structural constituent of cytoskeleton 17/768 112/18639 0.151785714285714 3.68376813616071 3.27063085917268e-06 0.000110024174145529 GO:0048027 mRNA 5'-UTR binding 8/768 24/18639 0.333333333333333 8.08984375 3.27383302452159e-06 0.000110024174145529 GO:0001618 virus receptor activity 14/768 81/18639 0.172839506172839 4.1947337962963 5.07033205968039e-06 0.000164523533384801 GO:0140272 exogenous protein binding 14/768 82/18639 0.170731707317073 4.14357850609756 5.88560060882961e-06 0.000184611672430289 GO:0051082 unfolded protein binding 17/768 121/18639 0.140495867768595 3.40976885330579 9.5150278439227e-06 0.000288827135520363 GO:0098632 cell-cell adhesion mediator activity 11/768 55/18639 0.2 4.85390625 1.23228811584688e-05 0.000362369724066222 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/768 88/18639 0.159090909090909 3.86106178977273 1.37006221391193e-05 0.000390675316148825 GO:0004129 cytochrome-c oxidase activity 6/768 15/18639 0.4 9.7078125 1.7451148906332e-05 0.000469186603453098 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/768 15/18639 0.4 9.7078125 1.7451148906332e-05 0.000469186603453098 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/768 16/18639 0.375 9.10107421875 2.69495362835912e-05 0.000704430934523869 GO:0043021 ribonucleoprotein complex binding 20/768 177/18639 0.112994350282486 2.74231991525424 4.3289067782243e-05 0.0010459436011678 GO:1990948 ubiquitin ligase inhibitor activity 5/768 11/18639 0.454545454545455 11.0316051136364 4.40209276393492e-05 0.0010459436011678 GO:0071889 14-3-3 protein binding 8/768 33/18639 0.242424242424242 5.88352272727273 4.44609394757831e-05 0.0010459436011678 GO:0140311 protein sequestering activity 8/768 33/18639 0.242424242424242 5.88352272727273 4.44609394757831e-05 0.0010459436011678 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 10/768 54/18639 0.185185185185185 4.49435763888889 6.14166592267793e-05 0.0014095872276195 GO:0050750 low-density lipoprotein particle receptor binding 7/768 26/18639 0.269230769230769 6.53410456730769 6.49379932449875e-05 0.00145492027722698 GO:0140313 molecular sequestering activity 10/768 55/18639 0.181818181818182 4.41264204545455 7.23263876864038e-05 0.00158277048402107 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 8/768 36/18639 0.222222222222222 5.39322916666667 8.68560601516489e-05 0.00177677288266743 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 8/768 36/18639 0.222222222222222 5.39322916666667 8.68560601516489e-05 0.00177677288266743 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 8/768 36/18639 0.222222222222222 5.39322916666667 8.68560601516489e-05 0.00177677288266743 GO:0044325 transmembrane transporter binding 16/768 136/18639 0.117647058823529 2.85523897058824 0.000153261264414098 0.00306848616624822 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/768 39/18639 0.205128205128205 4.97836538461538 0.000158310968282769 0.00310355460737678 GO:0015036 disulfide oxidoreductase activity 8/768 40/18639 0.2 4.85390625 0.000190817641344329 0.00359118801010027 GO:0140662 ATP-dependent protein folding chaperone 8/768 40/18639 0.2 4.85390625 0.000190817641344329 0.00359118801010027 GO:0043022 ribosome binding 14/768 112/18639 0.125 3.03369140625 0.000205776004285035 0.00379676902023957 GO:0070325 lipoprotein particle receptor binding 7/768 31/18639 0.225806451612903 5.48021673387097 0.000216894044296708 0.00392494799390774 GO:0016859 cis-trans isomerase activity 8/768 42/18639 0.19047619047619 4.62276785714286 0.000272319963209782 0.00483496387510198 GO:0008200 ion channel inhibitor activity 8/768 43/18639 0.186046511627907 4.51526162790698 0.000322628826999902 0.0056165230109976 GO:0031072 heat shock protein binding 15/768 131/18639 0.114503816793893 2.77895395992366 0.000328277115414313 0.0056165230109976 GO:0019207 kinase regulator activity 25/768 287/18639 0.0871080139372822 2.11407066637631 0.000364096781571295 0.00611812627604623 GO:0016248 channel inhibitor activity 8/768 44/18639 0.181818181818182 4.41264204545455 0.000380264104697172 0.00627769337754453 GO:0015035 protein-disulfide reductase activity 7/768 34/18639 0.205882352941176 4.99666819852941 0.000398483096809342 0.00646504472582053 GO:0048306 calcium-dependent protein binding 11/768 80/18639 0.1375 3.337060546875 0.000423775719197636 0.00675886358923687 GO:0141110 transporter inhibitor activity 8/768 45/18639 0.177777777777778 4.31458333333333 0.000446002072357987 0.00699479916814776 GO:0002020 protease binding 15/768 136/18639 0.110294117647059 2.67678653492647 0.00049169960194285 0.0072365619808459 GO:0019838 growth factor binding 15/768 136/18639 0.110294117647059 2.67678653492647 0.00049169960194285 0.0072365619808459 GO:0005528 FK506 binding 4/768 10/18639 0.4 9.7078125 0.000492178498165927 0.0072365619808459 GO:0030957 Tat protein binding 4/768 10/18639 0.4 9.7078125 0.000492178498165927 0.0072365619808459 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 5/768 18/18639 0.277777777777778 6.74153645833333 0.00064167263454637 0.00928944537089437 GO:0023023 MHC protein complex binding 7/768 37/18639 0.189189189189189 4.59153293918919 0.000685007895261771 0.00962078252897502 GO:0043394 proteoglycan binding 7/768 37/18639 0.189189189189189 4.59153293918919 0.000685007895261771 0.00962078252897502 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/768 11/18639 0.363636363636364 8.82528409090909 0.000748268538466828 0.0103547160984895 GO:0016209 antioxidant activity 11/768 86/18639 0.127906976744186 3.10424236918605 0.000791586381939889 0.0107954026870353 GO:0097718 disordered domain specific binding 6/768 28/18639 0.214285714285714 5.20061383928571 0.00083045281157646 0.0111636585099064 GO:0042288 MHC class I protein binding 5/768 20/18639 0.25 6.0673828125 0.00108427802003916 0.0138091814130409 GO:0043024 ribosomal small subunit binding 5/768 20/18639 0.25 6.0673828125 0.00108427802003916 0.0138091814130409 GO:0004859 phospholipase inhibitor activity 4/768 12/18639 0.333333333333333 8.08984375 0.0010859505043199 0.0138091814130409 GO:0005527 macrolide binding 4/768 12/18639 0.333333333333333 8.08984375 0.0010859505043199 0.0138091814130409 GO:0061134 peptidase regulator activity 20/768 226/18639 0.0884955752212389 2.14774612831858 0.00111990581741305 0.0140510849891424 GO:0019210 kinase inhibitor activity 11/768 90/18639 0.122222222222222 2.96627604166667 0.00116043556304517 0.0143680245371777 GO:0005080 protein kinase C binding 8/768 52/18639 0.153846153846154 3.73377403846154 0.00120850041708283 0.0147688167853889 GO:0042287 MHC protein binding 7/768 41/18639 0.170731707317073 4.14357850609756 0.00129684245544022 0.0156452403919134 GO:0019888 protein phosphatase regulator activity 12/768 107/18639 0.11214953271028 2.72181658878505 0.00151010207619316 0.0179874184012375 GO:0044548 S100 protein binding 4/768 14/18639 0.285714285714286 6.93415178571429 0.0020560106602262 0.0239844151412476 GO:0140297 DNA-binding transcription factor binding 34/768 488/18639 0.069672131147541 1.69090996413934 0.00206454583043682 0.0239844151412476 GO:0004860 protein kinase inhibitor activity 10/768 84/18639 0.119047619047619 2.88922991071429 0.00233883855117035 0.0268395984957476 GO:0050431 transforming growth factor beta binding 5/768 24/18639 0.208333333333333 5.05615234375 0.00259328474987905 0.0294009752968216 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/768 59/18639 0.135593220338983 3.29078389830508 0.00276672423880058 0.0309938989132303 GO:0019208 phosphatase regulator activity 12/768 117/18639 0.102564102564103 2.48918269230769 0.0032184149018682 0.035517180159961 GO:0055106 ubiquitin-protein transferase regulator activity 6/768 36/18639 0.166666666666667 4.044921875 0.00324599096042152 0.035517180159961 GO:0005159 insulin-like growth factor receptor binding 4/768 16/18639 0.25 6.0673828125 0.00350054244910164 0.0372766304191358 GO:0055102 lipase inhibitor activity 4/768 16/18639 0.25 6.0673828125 0.00350054244910164 0.0372766304191358 GO:0051087 protein-folding chaperone binding 13/768 134/18639 0.0970149253731343 2.3545067630597 0.00360386406152097 0.0372766304191358 GO:0003725 double-stranded RNA binding 9/768 75/18639 0.12 2.91234375 0.00360486011492174 0.0372766304191358 GO:0044183 protein folding chaperone 9/768 75/18639 0.12 2.91234375 0.00360486011492174 0.0372766304191358 GO:0005525 GTP binding 27/768 378/18639 0.0714285714285714 1.73353794642857 0.00407863958321541 0.041717389650062 GO:0030414 peptidase inhibitor activity 15/768 169/18639 0.0887573964497041 2.15410040680473 0.00432319582013786 0.043600685604447 GO:0016018 cyclosporin A binding 4/768 17/18639 0.235294117647059 5.71047794117647 0.00443006385368218 0.043600685604447 GO:0015252 proton channel activity 5/768 27/18639 0.185185185185185 4.49435763888889 0.00444810395114443 0.043600685604447 GO:0023026 MHC class II protein complex binding 5/768 27/18639 0.185185185185185 4.49435763888889 0.00444810395114443 0.043600685604447 GO:0019001 guanyl nucleotide binding 28/768 400/18639 0.07 1.6988671875 0.00460142119471153 0.0441830341247301 GO:0032561 guanyl ribonucleotide binding 28/768 400/18639 0.07 1.6988671875 0.00460142119471153 0.0441830341247301 GO:0046332 SMAD binding 9/768 79/18639 0.113924050632911 2.76488330696203 0.00510948086117688 0.0485658736400752 GO:0003746 translation elongation factor activity 4/768 18/18639 0.222222222222222 5.39322916666667 0.00551246134486384 0.0513586745100681 GO:0070064 proline-rich region binding 4/768 18/18639 0.222222222222222 5.39322916666667 0.00551246134486384 0.0513586745100681 GO:0005544 calcium-dependent phospholipid binding 7/768 53/18639 0.132075471698113 3.20540978773585 0.00580850000695888 0.0535862598681206 GO:0015485 cholesterol binding 7/768 54/18639 0.12962962962963 3.14605034722222 0.00644207935027735 0.0583424038587608 GO:0099106 ion channel regulator activity 14/768 160/18639 0.0875 2.123583984375 0.00647798822515221 0.0583424038587608 GO:0019903 protein phosphatase binding 13/768 144/18639 0.0902777777777778 2.19099934895833 0.00660746747504947 0.0583424038587608 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/768 128/18639 0.09375 2.2752685546875 0.00662739841616712 0.0583424038587608 GO:0005131 growth hormone receptor binding 3/768 10/18639 0.3 7.280859375 0.00672838942727117 0.0583424038587608 GO:0005522 profilin binding 3/768 10/18639 0.3 7.280859375 0.00672838942727117 0.0583424038587608 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/768 19/18639 0.210526315789474 5.109375 0.00675804678066412 0.0583424038587608 GO:0004866 endopeptidase inhibitor activity 14/768 161/18639 0.0869565217391304 2.11039402173913 0.00683479555235493 0.0584053241588185 GO:0033218 amide binding 19/768 247/18639 0.0769230769230769 1.86688701923077 0.0068894696935482 0.0584053241588185 GO:0008135 translation factor activity, RNA binding 9/768 83/18639 0.108433734939759 2.6316359186747 0.00706044318614975 0.0591020541075006 GO:0008307 structural constituent of muscle 6/768 42/18639 0.142857142857143 3.46707589285714 0.00709727110961484 0.0591020541075006 GO:0180051 translation factor activity 9/768 84/18639 0.107142857142857 2.60030691964286 0.00762703574234729 0.0629564967855158 GO:0097110 scaffold protein binding 8/768 70/18639 0.114285714285714 2.77366071428571 0.00794000518814171 0.0649699554960117 GO:0022804 active transmembrane transporter activity 30/768 457/18639 0.0656455142231947 1.59318585886214 0.00839056213811638 0.0680648187238579 GO:0004601 peroxidase activity 7/768 57/18639 0.12280701754386 2.98046875 0.00865197480314428 0.0695855409381091 GO:0002162 dystroglycan binding 3/768 11/18639 0.272727272727273 6.61896306818182 0.00897093476057279 0.0697656992537107 GO:0050786 RAGE receptor binding 3/768 11/18639 0.272727272727273 6.61896306818182 0.00897093476057279 0.0697656992537107 GO:0050998 nitric-oxide synthase binding 3/768 11/18639 0.272727272727273 6.61896306818182 0.00897093476057279 0.0697656992537107 GO:0070990 snRNP binding 3/768 11/18639 0.272727272727273 6.61896306818182 0.00897093476057279 0.0697656992537107 GO:0061135 endopeptidase regulator activity 15/768 184/18639 0.0815217391304348 1.97849439538043 0.00930412013097687 0.0716767666313402 GO:0140142 nucleocytoplasmic carrier activity 5/768 32/18639 0.15625 3.7921142578125 0.00936901412928252 0.0716767666313402 GO:0019887 protein kinase regulator activity 19/768 255/18639 0.0745098039215686 1.80831801470588 0.00953576555452492 0.0723641563452254 GO:0016247 channel regulator activity 14/768 168/18639 0.0833333333333333 2.0224609375 0.00979272762221645 0.0737196535400454 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 24/768 349/18639 0.0687679083094556 1.66896489971347 0.0101947703387508 0.0761371340378137 GO:0001786 phosphatidylserine binding 7/768 59/18639 0.11864406779661 2.87943591101695 0.0104055134632478 0.077099119440285 GO:0141108 transporter regulator activity 14/768 170/18639 0.0823529411764706 1.99866727941176 0.0108000925273635 0.0793975552206954 GO:0005049 nuclear export signal receptor activity 3/768 12/18639 0.25 6.0673828125 0.0115992628459904 0.0839608179852075 GO:0017166 vinculin binding 3/768 12/18639 0.25 6.0673828125 0.0115992628459904 0.0839608179852075 GO:0005516 calmodulin binding 16/768 207/18639 0.0772946859903382 1.87590579710145 0.0119609551180892 0.0859180058482588 GO:0017134 fibroblast growth factor binding 4/768 23/18639 0.173913043478261 4.22078804347826 0.0135551497715942 0.0966317873868954 GO:0005048 signal sequence binding 6/768 51/18639 0.117647058823529 2.85523897058824 0.0178638567482901 0.125824121335757 GO:0008191 metalloendopeptidase inhibitor activity 3/768 14/18639 0.214285714285714 5.20061383928571 0.0180512820194764 0.125824121335757 GO:0008494 translation activator activity 3/768 14/18639 0.214285714285714 5.20061383928571 0.0180512820194764 0.125824121335757 GO:0043531 ADP binding 5/768 38/18639 0.131578947368421 3.193359375 0.0190891688693408 0.132080205191542 GO:0001221 transcription coregulator binding 10/768 115/18639 0.0869565217391304 2.11039402173913 0.0204070393631386 0.140168058691339 GO:0050681 nuclear androgen receptor binding 4/768 26/18639 0.153846153846154 3.73377403846154 0.0207685720066125 0.140598750059154 GO:0070412 R-SMAD binding 4/768 26/18639 0.153846153846154 3.73377403846154 0.0207685720066125 0.140598750059154 GO:0051020 GTPase binding 21/768 315/18639 0.0666666666666667 1.61796875 0.0211704809370987 0.14210444764044 GO:0032934 sterol binding 7/768 68/18639 0.102941176470588 2.49833409926471 0.0215751920870252 0.14210444764044 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/768 15/18639 0.2 4.85390625 0.0218858531131167 0.14210444764044 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/768 15/18639 0.2 4.85390625 0.0218858531131167 0.14210444764044 GO:0050780 dopamine receptor binding 3/768 15/18639 0.2 4.85390625 0.0218858531131167 0.14210444764044 GO:0001664 G protein-coupled receptor binding 20/768 297/18639 0.0673400673400673 1.63431186868687 0.0218970721656363 0.14210444764044 GO:1990782 protein tyrosine kinase binding 10/768 117/18639 0.0854700854700855 2.07431891025641 0.0227175482700434 0.1464192665898 GO:0071949 FAD binding 5/768 40/18639 0.125 3.03369140625 0.02340606189408 0.149830641104281 GO:0035255 ionotropic glutamate receptor binding 4/768 27/18639 0.148148148148148 3.59548611111111 0.0236069142771287 0.150095313072825 GO:0031267 small GTPase binding 19/768 283/18639 0.0671378091872792 1.62940315812721 0.0257010943568453 0.162313622750278 GO:0019902 phosphatase binding 14/768 190/18639 0.0736842105263158 1.78828125 0.0258920306044111 0.162429338658339 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/768 16/18639 0.1875 4.550537109375 0.0261286171125048 0.162828004654748 GO:0046875 ephrin receptor binding 4/768 28/18639 0.142857142857143 3.46707589285714 0.0266689750148084 0.164022911692384 GO:0051019 mitogen-activated protein kinase binding 4/768 28/18639 0.142857142857143 3.46707589285714 0.0266689750148084 0.164022911692384 GO:0042277 peptide binding 17/768 249/18639 0.0682730923694779 1.65695594879518 0.0292277892889778 0.178593180006027 GO:0030169 low-density lipoprotein particle binding 3/768 17/18639 0.176470588235294 4.28285845588235 0.0307783070965382 0.183306246695206 GO:0032977 membrane insertase activity 3/768 17/18639 0.176470588235294 4.28285845588235 0.0307783070965382 0.183306246695206 GO:0048038 quinone binding 3/768 17/18639 0.176470588235294 4.28285845588235 0.0307783070965382 0.183306246695206 GO:0051787 misfolded protein binding 3/768 17/18639 0.176470588235294 4.28285845588235 0.0307783070965382 0.183306246695206 GO:0051721 protein phosphatase 2A binding 4/768 30/18639 0.133333333333333 3.2359375 0.0334752987493522 0.195974061865265 GO:0001046 core promoter sequence-specific DNA binding 5/768 44/18639 0.113636363636364 2.75790127840909 0.0338131578169898 0.195974061865265 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/768 44/18639 0.113636363636364 2.75790127840909 0.0338131578169898 0.195974061865265 GO:0003924 GTPase activity 21/768 331/18639 0.0634441087613293 1.53975878021148 0.033842635781004 0.195974061865265 GO:0072341 modified amino acid binding 8/768 91/18639 0.0879120879120879 2.13358516483517 0.0339466228310714 0.195974061865265 GO:0043178 alcohol binding 8/768 92/18639 0.0869565217391304 2.11039402173913 0.0358948436335899 0.205335484626073 GO:0019955 cytokine binding 11/768 144/18639 0.0763888888888889 1.85392252604167 0.0360046280162614 0.205335484626073 GO:1901681 sulfur compound binding 18/768 275/18639 0.0654545454545455 1.58855113636364 0.0363380884603332 0.205988802657672 GO:0017022 myosin binding 7/768 76/18639 0.0921052631578947 2.2353515625 0.0368416274379862 0.207592643228413 GO:0030515 snoRNA binding 4/768 32/18639 0.125 3.03369140625 0.0412024618335781 0.219474928586169 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/768 32/18639 0.125 3.03369140625 0.0412024618335781 0.219474928586169 GO:0051059 NF-kappaB binding 4/768 32/18639 0.125 3.03369140625 0.0412024618335781 0.219474928586169 GO:0003756 protein disulfide isomerase activity 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0005229 intracellularly calcium-gated chloride channel activity 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0050145 nucleoside monophosphate kinase activity 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0070003 threonine-type peptidase activity 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0140036 ubiquitin-modified protein reader activity 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0141147 intracellularly calcium-gated channel activity 3/768 19/18639 0.157894736842105 3.83203125 0.0412827442717873 0.219474928586169 GO:0004867 serine-type endopeptidase inhibitor activity 8/768 95/18639 0.0842105263157895 2.04375 0.0421874648157798 0.223024743773308 GO:0005539 glycosaminoglycan binding 16/768 242/18639 0.0661157024793388 1.60459710743802 0.0430990371946611 0.226570916202101 GO:0005507 copper ion binding 6/768 63/18639 0.0952380952380952 2.31138392857143 0.0447548373757974 0.233968344281252 GO:0019956 chemokine binding 4/768 33/18639 0.121212121212121 2.94176136363636 0.0454129959291094 0.234800160270835 GO:0030296 protein tyrosine kinase activator activity 4/768 33/18639 0.121212121212121 2.94176136363636 0.0454129959291094 0.234800160270835 GO:0008376 acetylgalactosaminyltransferase activity 4/768 34/18639 0.117647058823529 2.85523897058824 0.0498544010815181 0.253196735838008 GO:0051427 hormone receptor binding 4/768 34/18639 0.117647058823529 2.85523897058824 0.0498544010815181 0.253196735838008 GO:0001222 transcription corepressor binding 5/768 49/18639 0.102040816326531 2.47648278061224 0.050316460788212 0.253196735838008 GO:0035254 glutamate receptor binding 5/768 49/18639 0.102040816326531 2.47648278061224 0.050316460788212 0.253196735838008 GO:0060590 ATPase regulator activity 5/768 49/18639 0.102040816326531 2.47648278061224 0.050316460788212 0.253196735838008 GO:0120013 lipid transfer activity 6/768 65/18639 0.0923076923076923 2.24026442307692 0.0508450315987844 0.25449561028966 GO:0140104 molecular carrier activity 16/768 249/18639 0.0642570281124498 1.55948795180723 0.0532520040429693 0.262838217044065 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/768 21/18639 0.142857142857143 3.46707589285714 0.0533497337464573 0.262838217044065 GO:0072542 protein phosphatase activator activity 3/768 21/18639 0.142857142857143 3.46707589285714 0.0533497337464573 0.262838217044065 GO:0016229 steroid dehydrogenase activity 4/768 35/18639 0.114285714285714 2.77366071428571 0.0545255867964582 0.267232172788891 GO:0016922 nuclear receptor binding 10/768 137/18639 0.072992700729927 1.77149863138686 0.0569784774702971 0.277806980826682 GO:0051117 ATPase binding 7/768 84/18639 0.0833333333333333 2.0224609375 0.0579160496541408 0.280922694456425 GO:0008093 cytoskeletal anchor activity 3/768 22/18639 0.136363636363636 3.30948153409091 0.0599469836435466 0.287806691880497 GO:0140035 ubiquitin-like protein reader activity 3/768 22/18639 0.136363636363636 3.30948153409091 0.0599469836435466 0.287806691880497 GO:0005548 phospholipid transporter activity 6/768 68/18639 0.0882352941176471 2.14142922794118 0.0608867680394665 0.289708557406872 GO:0042975 peroxisome proliferator activated receptor binding 2/768 10/18639 0.2 4.85390625 0.0612667406205818 0.289708557406872 GO:0050815 phosphoserine residue binding 2/768 10/18639 0.2 4.85390625 0.0612667406205818 0.289708557406872 GO:0050660 flavin adenine dinucleotide binding 7/768 86/18639 0.0813953488372093 1.9754269622093 0.0641456331653588 0.301805204043013 GO:0030551 cyclic nucleotide binding 4/768 37/18639 0.108108108108108 2.62373310810811 0.0645500712408969 0.302048134116333 GO:0005319 lipid transporter activity 12/768 178/18639 0.0674157303370786 1.6361481741573 0.0648392381418695 0.302048134116333 GO:0004864 protein phosphatase inhibitor activity 5/768 53/18639 0.0943396226415094 2.28957841981132 0.0663877435539417 0.307113751022455 GO:0004602 glutathione peroxidase activity 3/768 23/18639 0.130434782608696 3.1655910326087 0.0669057587243394 0.307113751022455 GO:0031681 G-protein beta-subunit binding 3/768 23/18639 0.130434782608696 3.1655910326087 0.0669057587243394 0.307113751022455 GO:0016853 isomerase activity 12/768 180/18639 0.0666666666666667 1.61796875 0.0692735755686451 0.316439002961626 GO:0000146 microfilament motor activity 4/768 38/18639 0.105263157894737 2.5546875 0.069898412696374 0.317750755300908 GO:0030246 carbohydrate binding 17/768 280/18639 0.0607142857142857 1.47350725446429 0.0722695797582275 0.319012265087465 GO:0010854 adenylate cyclase regulator activity 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0034511 U3 snoRNA binding 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0048407 platelet-derived growth factor binding 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0097493 structural molecule activity conferring elasticity 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0140031 phosphorylation-dependent protein binding 2/768 11/18639 0.181818181818182 4.41264204545455 0.0728880308116949 0.319012265087465 GO:0030552 cAMP binding 3/768 24/18639 0.125 3.03369140625 0.0742140781455397 0.323312257106263 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/768 39/18639 0.102564102564103 2.48918269230769 0.0754666815737326 0.327254135303606 GO:0019212 phosphatase inhibitor activity 5/768 56/18639 0.0892857142857143 2.16692243303571 0.08010571692894 0.345777429496021 GO:0005537 D-mannose binding 3/768 25/18639 0.12 2.91234375 0.0818591445388253 0.348549570185677 GO:0019211 phosphatase activator activity 3/768 25/18639 0.12 2.91234375 0.0818591445388253 0.348549570185677 GO:0042974 nuclear retinoic acid receptor binding 3/768 25/18639 0.12 2.91234375 0.0818591445388253 0.348549570185677 GO:0016504 peptidase activator activity 5/768 57/18639 0.087719298245614 2.12890625 0.0849896644691478 0.356433108207712 GO:0010853 cyclase activator activity 2/768 12/18639 0.166666666666667 4.044921875 0.0851457844048359 0.356433108207712 GO:0070008 serine-type exopeptidase activity 2/768 12/18639 0.166666666666667 4.044921875 0.0851457844048359 0.356433108207712 GO:0035591 signaling adaptor activity 9/768 129/18639 0.0697674418604651 1.69322311046512 0.0855145469894266 0.356433108207712 GO:0019209 kinase activator activity 10/768 148/18639 0.0675675675675676 1.63983319256757 0.0856045509616821 0.356433108207712 GO:0017080 sodium channel regulator activity 4/768 41/18639 0.0975609756097561 2.36775914634146 0.0872478436110978 0.361674981665388 GO:0042562 hormone binding 7/768 94/18639 0.074468085106383 1.80730551861702 0.0929717175769619 0.382341079642518 GO:0031492 nucleosomal DNA binding 4/768 42/18639 0.0952380952380952 2.31138392857143 0.0934521236108175 0.382341079642518 GO:0051879 Hsp90 protein binding 4/768 42/18639 0.0952380952380952 2.31138392857143 0.0934521236108175 0.382341079642518 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/768 13/18639 0.153846153846154 3.73377403846154 0.0979679772291577 0.392837671552039 GO:0030955 potassium ion binding 2/768 13/18639 0.153846153846154 3.73377403846154 0.0979679772291577 0.392837671552039 GO:0031994 insulin-like growth factor I binding 2/768 13/18639 0.153846153846154 3.73377403846154 0.0979679772291577 0.392837671552039 GO:0001671 ATPase activator activity 3/768 27/18639 0.111111111111111 2.69661458333333 0.0981050508126771 0.392837671552039 GO:0004364 glutathione transferase activity 3/768 27/18639 0.111111111111111 2.69661458333333 0.0981050508126771 0.392837671552039 GO:0030547 signaling receptor inhibitor activity 4/768 44/18639 0.0909090909090909 2.20632102272727 0.106463766719289 0.421779052495061 GO:0019789 SUMO transferase activity 3/768 28/18639 0.107142857142857 2.60030691964286 0.106677379908421 0.421779052495061 GO:0051393 alpha-actinin binding 3/768 28/18639 0.107142857142857 2.60030691964286 0.106677379908421 0.421779052495061 GO:0042626 ATPase-coupled transmembrane transporter activity 7/768 98/18639 0.0714285714285714 1.73353794642857 0.109699642030412 0.431913653349864 GO:0032036 myosin heavy chain binding 2/768 14/18639 0.142857142857143 3.46707589285714 0.111287426430771 0.434528913989028 GO:1990825 sequence-specific mRNA binding 2/768 14/18639 0.142857142857143 3.46707589285714 0.111287426430771 0.434528913989028 GO:0003785 actin monomer binding 3/768 29/18639 0.103448275862069 2.5106411637931 0.115529650859005 0.449228931645967 GO:0030971 receptor tyrosine kinase binding 6/768 81/18639 0.0740740740740741 1.79774305555556 0.116898206157423 0.452679884749528 GO:0043130 ubiquitin binding 7/768 100/18639 0.07 1.6988671875 0.118624549975865 0.457482383308561 GO:0004180 carboxypeptidase activity 4/768 46/18639 0.0869565217391304 2.11039402173913 0.120243330097301 0.459955177323416 GO:0030291 protein serine/threonine kinase inhibitor activity 4/768 46/18639 0.0869565217391304 2.11039402173913 0.120243330097301 0.459955177323416 GO:0098918 structural constituent of synapse 3/768 30/18639 0.1 2.426953125 0.124646801093411 0.468781136534309 GO:0005523 tropomyosin binding 2/768 15/18639 0.133333333333333 3.2359375 0.125041514633487 0.468781136534309 GO:0015929 hexosaminidase activity 2/768 15/18639 0.133333333333333 3.2359375 0.125041514633487 0.468781136534309 GO:0033130 acetylcholine receptor binding 2/768 15/18639 0.133333333333333 3.2359375 0.125041514633487 0.468781136534309 GO:0050700 CARD domain binding 2/768 15/18639 0.133333333333333 3.2359375 0.125041514633487 0.468781136534309 GO:0043495 protein-membrane adaptor activity 4/768 47/18639 0.0851063829787234 2.0654920212766 0.127406471794516 0.475751944280315 GO:0008238 exopeptidase activity 7/768 102/18639 0.0686274509803922 1.66555606617647 0.127912958664501 0.475755312661247 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0005024 transforming growth factor beta receptor activity 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0005521 lamin binding 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0008142 oxysterol binding 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0008296 3'-5'-DNA exonuclease activity 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0043023 ribosomal large subunit binding 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0070411 I-SMAD binding 2/768 16/18639 0.125 3.03369140625 0.139171928565056 0.503695326075838 GO:0016887 ATP hydrolysis activity 22/768 417/18639 0.052757793764988 1.28040692446043 0.141685272124349 0.510826977275909 GO:0071813 lipoprotein particle binding 3/768 32/18639 0.09375 2.2752685546875 0.143614759762403 0.511899579304626 GO:0071814 protein-lipid complex binding 3/768 32/18639 0.09375 2.2752685546875 0.143614759762403 0.511899579304626 GO:0120015 sterol transfer activity 3/768 32/18639 0.09375 2.2752685546875 0.143614759762403 0.511899579304626 GO:1990841 promoter-specific chromatin binding 5/768 68/18639 0.0735294117647059 1.78452435661765 0.148273631440456 0.526511272397996 GO:0008429 phosphatidylethanolamine binding 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0008484 sulfuric ester hydrolase activity 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0030548 acetylcholine receptor regulator activity 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0046965 nuclear retinoid X receptor binding 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0070402 NADPH binding 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0070492 oligosaccharide binding 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:1990226 histone methyltransferase binding 2/768 17/18639 0.117647058823529 2.85523897058824 0.153624411427525 0.527593325377012 GO:0004197 cysteine-type endopeptidase activity 6/768 88/18639 0.0681818181818182 1.65474076704545 0.154930960804288 0.530145578606673 GO:0005085 guanyl-nucleotide exchange factor activity 13/768 230/18639 0.0565217391304348 1.37175611413043 0.155796430528585 0.531175511331153 GO:0003743 translation initiation factor activity 4/768 51/18639 0.0784313725490196 1.90349264705882 0.157733409886331 0.534335814595044 GO:0005496 steroid binding 7/768 108/18639 0.0648148148148148 1.57302517361111 0.157859039805975 0.534335814595044 GO:0000900 mRNA regulatory element binding translation repressor activity 2/768 18/18639 0.111111111111111 2.69661458333333 0.168348528325107 0.560263191893511 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/768 18/18639 0.111111111111111 2.69661458333333 0.168348528325107 0.560263191893511 GO:0017128 phospholipid scramblase activity 2/768 18/18639 0.111111111111111 2.69661458333333 0.168348528325107 0.560263191893511 GO:0099602 neurotransmitter receptor regulator activity 2/768 18/18639 0.111111111111111 2.69661458333333 0.168348528325107 0.560263191893511 GO:0004222 metalloendopeptidase activity 7/768 110/18639 0.0636363636363636 1.54442471590909 0.168495731462129 0.560263191893511 GO:0003713 transcription coactivator activity 14/768 256/18639 0.0546875 1.32723999023438 0.172842018615168 0.565926704790253 GO:0008201 heparin binding 10/768 172/18639 0.0581395348837209 1.41101925872093 0.173270383085101 0.565926704790253 GO:0005154 epidermal growth factor receptor binding 3/768 35/18639 0.0857142857142857 2.08024553571429 0.173671353153016 0.565926704790253 GO:0140566 histone reader activity 3/768 35/18639 0.0857142857142857 2.08024553571429 0.173671353153016 0.565926704790253 GO:0005246 calcium channel regulator activity 4/768 53/18639 0.0754716981132075 1.83166273584906 0.173807457687973 0.565926704790253 GO:0051018 protein kinase A binding 4/768 53/18639 0.0754716981132075 1.83166273584906 0.173807457687973 0.565926704790253 GO:0003925 G protein activity 4/768 54/18639 0.0740740740740741 1.79774305555556 0.182047785441322 0.577326698382887 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/768 54/18639 0.0740740740740741 1.79774305555556 0.182047785441322 0.577326698382887 GO:0140463 chromatin-protein adaptor activity 4/768 54/18639 0.0740740740740741 1.79774305555556 0.182047785441322 0.577326698382887 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/768 19/18639 0.105263157894737 2.5546875 0.183297444096086 0.577326698382887 GO:0005520 insulin-like growth factor binding 2/768 19/18639 0.105263157894737 2.5546875 0.183297444096086 0.577326698382887 GO:0030506 ankyrin binding 2/768 19/18639 0.105263157894737 2.5546875 0.183297444096086 0.577326698382887 GO:0031420 alkali metal ion binding 2/768 19/18639 0.105263157894737 2.5546875 0.183297444096086 0.577326698382887 GO:0043395 heparan sulfate proteoglycan binding 2/768 19/18639 0.105263157894737 2.5546875 0.183297444096086 0.577326698382887 GO:1990380 K48-linked deubiquitinase activity 2/768 19/18639 0.105263157894737 2.5546875 0.183297444096086 0.577326698382887 GO:0005484 SNAP receptor activity 3/768 36/18639 0.0833333333333333 2.0224609375 0.184057395871271 0.577326698382887 GO:0016409 palmitoyltransferase activity 3/768 36/18639 0.0833333333333333 2.0224609375 0.184057395871271 0.577326698382887 GO:0042805 actinin binding 3/768 37/18639 0.0810810810810811 1.96779983108108 0.194602159809245 0.608210025616239 GO:0017124 SH3 domain binding 7/768 115/18639 0.0608695652173913 1.47727581521739 0.196391515939116 0.608210025616239 GO:0010851 cyclase regulator activity 2/768 20/18639 0.1 2.426953125 0.198427712926871 0.608210025616239 GO:0015095 magnesium ion transmembrane transporter activity 2/768 20/18639 0.1 2.426953125 0.198427712926871 0.608210025616239 GO:0016408 C-acyltransferase activity 2/768 20/18639 0.1 2.426953125 0.198427712926871 0.608210025616239 GO:0016505 peptidase activator activity involved in apoptotic process 2/768 20/18639 0.1 2.426953125 0.198427712926871 0.608210025616239 GO:0061608 nuclear import signal receptor activity 2/768 20/18639 0.1 2.426953125 0.198427712926871 0.608210025616239 GO:0042162 telomeric DNA binding 3/768 38/18639 0.0789473684210526 1.916015625 0.20529105241892 0.627204156903259 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/768 21/18639 0.0952380952380952 2.31138392857143 0.213699079156388 0.648680108019875 GO:0001846 opsonin binding 2/768 21/18639 0.0952380952380952 2.31138392857143 0.213699079156388 0.648680108019875 GO:0019199 transmembrane receptor protein kinase activity 5/768 78/18639 0.0641025641025641 1.55573918269231 0.218538075387196 0.661235784370904 GO:0036002 pre-mRNA binding 4/768 59/18639 0.0677966101694915 1.64539194915254 0.224996665535991 0.67859571240182 GO:0032182 ubiquitin-like protein binding 7/768 120/18639 0.0583333333333333 1.41572265625 0.225959097397735 0.679321120291593 GO:0008237 metallopeptidase activity 10/768 184/18639 0.0543478260869565 1.31899626358696 0.228623699925406 0.679996547867255 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/768 22/18639 0.0909090909090909 2.20632102272727 0.229074288707672 0.679996547867255 GO:0031683 G-protein beta/gamma-subunit complex binding 2/768 22/18639 0.0909090909090909 2.20632102272727 0.229074288707672 0.679996547867255 GO:0070034 telomerase RNA binding 2/768 22/18639 0.0909090909090909 2.20632102272727 0.229074288707672 0.679996547867255 GO:0015026 coreceptor activity 4/768 61/18639 0.0655737704918033 1.59144467213115 0.242857699335392 0.714572344362755 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/768 61/18639 0.0655737704918033 1.59144467213115 0.242857699335392 0.714572344362755 GO:0070577 lysine-acetylated histone binding 2/768 23/18639 0.0869565217391304 2.11039402173913 0.244518910610847 0.714572344362755 GO:0099186 structural constituent of postsynapse 2/768 23/18639 0.0869565217391304 2.11039402173913 0.244518910610847 0.714572344362755 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/768 23/18639 0.0869565217391304 2.11039402173913 0.244518910610847 0.714572344362755 GO:0005126 cytokine receptor binding 14/768 275/18639 0.0509090909090909 1.23553977272727 0.24550212952529 0.715224470226928 GO:0140597 protein carrier chaperone 10/768 188/18639 0.0531914893617021 1.29093251329787 0.248439842684032 0.719334072850447 GO:0042056 chemoattractant activity 3/768 42/18639 0.0714285714285714 1.73353794642857 0.249206065620877 0.719334072850447 GO:0048487 beta-tubulin binding 3/768 42/18639 0.0714285714285714 1.73353794642857 0.249206065620877 0.719334072850447 GO:0016874 ligase activity 9/768 167/18639 0.0538922155688623 1.30793880988024 0.251794578283594 0.724583174816093 GO:0005254 chloride channel activity 5/768 83/18639 0.0602409638554217 1.46201995481928 0.256933506291138 0.731471836406991 GO:0005540 hyaluronic acid binding 2/768 24/18639 0.0833333333333333 2.0224609375 0.260001168107693 0.731471836406991 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/768 24/18639 0.0833333333333333 2.0224609375 0.260001168107693 0.731471836406991 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/768 24/18639 0.0833333333333333 2.0224609375 0.260001168107693 0.731471836406991 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/768 24/18639 0.0833333333333333 2.0224609375 0.260001168107693 0.731471836406991 GO:0070300 phosphatidic acid binding 2/768 24/18639 0.0833333333333333 2.0224609375 0.260001168107693 0.731471836406991 GO:0140033 acetylation-dependent protein binding 2/768 24/18639 0.0833333333333333 2.0224609375 0.260001168107693 0.731471836406991 GO:0048156 tau protein binding 3/768 43/18639 0.0697674418604651 1.69322311046512 0.260407083099194 0.731471836406991 GO:0001223 transcription coactivator binding 3/768 44/18639 0.0681818181818182 1.65474076704545 0.271671228200163 0.751413808407233 GO:0019205 nucleobase-containing compound kinase activity 3/768 44/18639 0.0681818181818182 1.65474076704545 0.271671228200163 0.751413808407233 GO:0000030 mannosyltransferase activity 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0008139 nuclear localization sequence binding 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0015662 P-type ion transporter activity 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0019707 protein-cysteine S-acyltransferase activity 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0120020 cholesterol transfer activity 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0140358 P-type transmembrane transporter activity 2/768 25/18639 0.08 1.9415625 0.275491778852811 0.751413808407233 GO:0042605 peptide antigen binding 3/768 45/18639 0.0666666666666667 1.61796875 0.282986286158155 0.76693820540267 GO:0140303 intramembrane lipid transporter activity 3/768 45/18639 0.0666666666666667 1.61796875 0.282986286158155 0.76693820540267 GO:0008235 metalloexopeptidase activity 4/768 66/18639 0.0606060606060606 1.47088068181818 0.288719889154911 0.76693820540267 GO:0004529 DNA exonuclease activity 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0005160 transforming growth factor beta receptor binding 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0005227 calcium-activated cation channel activity 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0008198 ferrous iron binding 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0019865 immunoglobulin binding 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0034237 protein kinase A regulatory subunit binding 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0070006 metalloaminopeptidase activity 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0097602 cullin family protein binding 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0120014 phospholipid transfer activity 2/768 26/18639 0.0769230769230769 1.86688701923077 0.290963803750004 0.76693820540267 GO:0016758 hexosyltransferase activity 10/768 197/18639 0.050761421319797 1.23195590101523 0.29500586235301 0.775420437078721 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/768 67/18639 0.0597014925373134 1.44892723880597 0.298045080416897 0.781226798530085 GO:0005504 fatty acid binding 3/768 47/18639 0.0638297872340425 1.54911901595745 0.305722307753022 0.787234059987432 GO:0061749 forked DNA-dependent helicase activity 3/768 47/18639 0.0638297872340425 1.54911901595745 0.305722307753022 0.787234059987432 GO:0099095 ligand-gated monoatomic anion channel activity 3/768 47/18639 0.0638297872340425 1.54911901595745 0.305722307753022 0.787234059987432 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/768 47/18639 0.0638297872340425 1.54911901595745 0.305722307753022 0.787234059987432 GO:0008266 poly(U) RNA binding 2/768 27/18639 0.0740740740740741 1.79774305555556 0.30639250398499 0.787234059987432 GO:0008320 protein transmembrane transporter activity 2/768 27/18639 0.0740740740740741 1.79774305555556 0.30639250398499 0.787234059987432 GO:0030145 manganese ion binding 4/768 68/18639 0.0588235294117647 1.42761948529412 0.307405795977925 0.787234059987432 GO:0016757 glycosyltransferase activity 13/768 267/18639 0.048689138576779 1.18166257022472 0.308282365669278 0.787234059987432 GO:0009378 four-way junction helicase activity 3/768 48/18639 0.0625 1.516845703125 0.317120889249122 0.787234059987432 GO:0036121 double-stranded DNA helicase activity 3/768 48/18639 0.0625 1.516845703125 0.317120889249122 0.787234059987432 GO:0043138 3'-5' DNA helicase activity 3/768 48/18639 0.0625 1.516845703125 0.317120889249122 0.787234059987432 GO:0045499 chemorepellent activity 2/768 28/18639 0.0714285714285714 1.73353794642857 0.321755205837033 0.787234059987432 GO:0046625 sphingolipid binding 2/768 28/18639 0.0714285714285714 1.73353794642857 0.321755205837033 0.787234059987432 GO:0046966 nuclear thyroid hormone receptor binding 2/768 28/18639 0.0714285714285714 1.73353794642857 0.321755205837033 0.787234059987432 GO:0016417 S-acyltransferase activity 2/768 29/18639 0.0689655172413793 1.67376077586207 0.337031172872443 0.787234059987432 GO:0051219 phosphoprotein binding 5/768 93/18639 0.0537634408602151 1.30481350806452 0.337544116999628 0.787234059987432 GO:0048020 CCR chemokine receptor binding 3/768 50/18639 0.06 1.456171875 0.339926386884469 0.787234059987432 GO:0001094 TFIID-class transcription factor complex binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0004955 prostaglandin receptor activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0008140 cAMP response element binding protein binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0008190 eukaryotic initiation factor 4E binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0008239 dipeptidyl-peptidase activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0016868 intramolecular phosphotransferase activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0031996 thioesterase binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0032356 oxidized DNA binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0035374 chondroitin sulfate binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0043208 glycosphingolipid binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0043422 protein kinase B binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0047429 nucleoside triphosphate diphosphatase activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0051880 G-quadruplex DNA binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0070513 death domain binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0140135 mechanosensitive monoatomic cation channel activity 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:1990763 arrestin family protein binding 1/768 10/18639 0.1 2.426953125 0.343526212550499 0.787234059987432 GO:0030295 protein kinase activator activity 7/768 139/18639 0.0503597122302158 1.22220660971223 0.348852817000038 0.787234059987432 GO:0070851 growth factor receptor binding 7/768 139/18639 0.0503597122302158 1.22220660971223 0.348852817000038 0.787234059987432 GO:0000287 magnesium ion binding 11/768 230/18639 0.0478260869565217 1.16071671195652 0.349986494288012 0.787234059987432 GO:0008187 poly-pyrimidine tract binding 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0022839 monoatomic ion-gated channel activity 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0031210 phosphatidylcholine binding 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0033612 receptor serine/threonine kinase binding 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0048019 receptor antagonist activity 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0070566 adenylyltransferase activity 2/768 30/18639 0.0666666666666667 1.61796875 0.352201485142374 0.787234059987432 GO:0004713 protein tyrosine kinase activity 7/768 140/18639 0.05 1.2134765625 0.355597203546822 0.787234059987432 GO:0003678 DNA helicase activity 4/768 74/18639 0.0540540540540541 1.31186655405405 0.363969553333385 0.787234059987432 GO:0003684 damaged DNA binding 4/768 74/18639 0.0540540540540541 1.31186655405405 0.363969553333385 0.787234059987432 GO:0031491 nucleosome binding 4/768 74/18639 0.0540540540540541 1.31186655405405 0.363969553333385 0.787234059987432 GO:0048029 monosaccharide binding 4/768 74/18639 0.0540540540540541 1.31186655405405 0.363969553333385 0.787234059987432 GO:0031406 carboxylic acid binding 9/768 187/18639 0.0481283422459893 1.16805230614973 0.365236015990793 0.787234059987432 GO:0070273 phosphatidylinositol-4-phosphate binding 2/768 31/18639 0.0645161290322581 1.56577620967742 0.367248925025878 0.787234059987432 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0004954 prostanoid receptor activity 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0005536 D-glucose binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0008199 ferric iron binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0008432 JUN kinase binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0008503 benzodiazepine receptor activity 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0008526 phosphatidylinositol transfer activity 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0019215 intermediate filament binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0032794 GTPase activating protein binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0034713 type I transforming growth factor beta receptor binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0042608 T cell receptor binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0045294 alpha-catenin binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0048185 activin binding 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0180030 inositol phosphate kinase activity 1/768 11/18639 0.0909090909090909 2.20632102272727 0.370590030724379 0.787234059987432 GO:0016860 intramolecular oxidoreductase activity 3/768 53/18639 0.0566037735849057 1.37374705188679 0.374009721248414 0.787234059987432 GO:0017046 peptide hormone binding 3/768 53/18639 0.0566037735849057 1.37374705188679 0.374009721248414 0.787234059987432 GO:0043177 organic acid binding 9/768 189/18639 0.0476190476190476 1.15569196428571 0.376989574937256 0.787234059987432 GO:0022884 macromolecule transmembrane transporter activity 2/768 32/18639 0.0625 1.516845703125 0.382157869376776 0.787234059987432 GO:0031369 translation initiation factor binding 2/768 32/18639 0.0625 1.516845703125 0.382157869376776 0.787234059987432 GO:0017069 snRNA binding 3/768 54/18639 0.0555555555555556 1.34830729166667 0.385301599825301 0.787234059987432 GO:0050661 NADP binding 3/768 54/18639 0.0555555555555556 1.34830729166667 0.385301599825301 0.787234059987432 GO:0003712 transcription coregulator activity 22/768 495/18639 0.0444444444444444 1.07864583333333 0.388200578144326 0.787234059987432 GO:0005543 phospholipid binding 22/768 497/18639 0.0442655935613682 1.07430520623742 0.395533356290274 0.787234059987432 GO:0000340 RNA 7-methylguanosine cap binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0005025 transforming growth factor beta receptor activity, type I 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0005026 transforming growth factor beta receptor activity, type II 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0005095 GTPase inhibitor activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0005165 neurotrophin receptor binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0005247 voltage-gated chloride channel activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0008179 adenylate cyclase binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0008603 cAMP-dependent protein kinase regulator activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0016208 AMP binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0016361 activin receptor activity, type I 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0016362 activin receptor activity, type II 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0017002 activin receptor activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0035259 nuclear glucocorticoid receptor binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0035497 cAMP response element binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0045295 gamma-catenin binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0097371 MDM2/MDM4 family protein binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0097677 STAT family protein binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:1990459 transferrin receptor binding 1/768 12/18639 0.0833333333333333 2.0224609375 0.396539507662519 0.787234059987432 GO:0008374 O-acyltransferase activity 3/768 55/18639 0.0545454545454545 1.32379261363636 0.396545105668483 0.787234059987432 GO:0004175 endopeptidase activity 18/768 405/18639 0.0444444444444444 1.07864583333333 0.404887366435532 0.791109919380716 GO:0016835 carbon-oxygen lyase activity 4/768 79/18639 0.0506329113924051 1.22883702531646 0.411000708781495 0.791109919380716 GO:0033293 monocarboxylic acid binding 4/768 79/18639 0.0506329113924051 1.22883702531646 0.411000708781495 0.791109919380716 GO:0015020 glucuronosyltransferase activity 2/768 34/18639 0.0588235294117647 1.42761948529412 0.411505145696988 0.791109919380716 GO:0030332 cyclin binding 2/768 34/18639 0.0588235294117647 1.42761948529412 0.411505145696988 0.791109919380716 GO:0004722 protein serine/threonine phosphatase activity 5/768 103/18639 0.0485436893203883 1.17813258495146 0.41980905445819 0.791109919380716 GO:0005253 monoatomic anion channel activity 5/768 103/18639 0.0485436893203883 1.17813258495146 0.41980905445819 0.791109919380716 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0005035 death receptor activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0005172 vascular endothelial growth factor receptor binding 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0005542 folic acid binding 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0008253 5'-nucleotidase activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0008417 fucosyltransferase activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0017154 semaphorin receptor activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0019104 DNA N-glycosylase activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0019855 calcium channel inhibitor activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0031432 titin binding 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0039706 co-receptor binding 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0045159 myosin II binding 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0070123 transforming growth factor beta receptor activity, type III 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0070700 BMP receptor binding 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0140333 glycerophospholipid flippase activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0140666 annealing activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/768 13/18639 0.0769230769230769 1.86688701923077 0.421420468531966 0.791109919380716 GO:0000175 3'-5'-RNA exonuclease activity 2/768 35/18639 0.0571428571428571 1.38683035714286 0.425919314942077 0.791109919380716 GO:0043015 gamma-tubulin binding 2/768 35/18639 0.0571428571428571 1.38683035714286 0.425919314942077 0.791109919380716 GO:0033192 calmodulin-dependent protein phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0140791 histone H2AXS140 phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/768 81/18639 0.0493827160493827 1.19849537037037 0.429629765973053 0.791109919380716 GO:0017116 single-stranded DNA helicase activity 3/768 58/18639 0.0517241379310345 1.25532058189655 0.429910955585459 0.791109919380716 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/768 82/18639 0.0487804878048781 1.18387957317073 0.438886638068239 0.791109919380716 GO:0033549 MAP kinase phosphatase activity 4/768 82/18639 0.0487804878048781 1.18387957317073 0.438886638068239 0.791109919380716 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/768 36/18639 0.0555555555555556 1.34830729166667 0.440146486652125 0.791109919380716 GO:0045309 protein phosphorylated amino acid binding 3/768 59/18639 0.0508474576271186 1.23404396186441 0.440888506838109 0.791109919380716 GO:0070063 RNA polymerase binding 3/768 59/18639 0.0508474576271186 1.23404396186441 0.440888506838109 0.791109919380716 GO:0008013 beta-catenin binding 5/768 106/18639 0.0471698113207547 1.14478920990566 0.444256915747111 0.791109919380716 GO:0004065 arylsulfatase activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0004705 JUN kinase activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0008195 phosphatidate phosphatase activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0016530 metallochaperone activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0019992 diacylglycerol binding 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0031404 chloride ion binding 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0034236 protein kinase A catalytic subunit binding 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0042043 neurexin family protein binding 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0046030 inositol trisphosphate phosphatase activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0071933 Arp2/3 complex binding 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0098821 BMP receptor activity 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0098847 sequence-specific single stranded DNA binding 1/768 14/18639 0.0714285714285714 1.73353794642857 0.445276856385904 0.791109919380716 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/768 130/18639 0.0461538461538462 1.12013221153846 0.447825005504291 0.791109919380716 GO:0001540 amyloid-beta binding 4/768 83/18639 0.0481927710843374 1.16961596385542 0.448099454867079 0.791109919380716 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/768 83/18639 0.0481927710843374 1.16961596385542 0.448099454867079 0.791109919380716 GO:0030165 PDZ domain binding 4/768 83/18639 0.0481927710843374 1.16961596385542 0.448099454867079 0.791109919380716 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/768 60/18639 0.05 1.2134765625 0.45178339424618 0.792319984919955 GO:0019213 deacetylase activity 2/768 37/18639 0.0540540540540541 1.31186655405405 0.454177591043146 0.792319984919955 GO:0017018 myosin phosphatase activity 4/768 84/18639 0.0476190476190476 1.15569196428571 0.457264211703313 0.792319984919955 GO:0005179 hormone activity 6/768 132/18639 0.0454545454545455 1.10316051136364 0.462416089395487 0.792319984919955 GO:0019905 syntaxin binding 3/768 61/18639 0.0491803278688525 1.19358350409836 0.462589895707083 0.792319984919955 GO:0005109 frizzled binding 2/768 38/18639 0.0526315789473684 1.27734375 0.468004620966714 0.792319984919955 GO:0005501 retinoid binding 2/768 38/18639 0.0526315789473684 1.27734375 0.468004620966714 0.792319984919955 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/768 38/18639 0.0526315789473684 1.27734375 0.468004620966714 0.792319984919955 GO:0019840 isoprenoid binding 2/768 38/18639 0.0526315789473684 1.27734375 0.468004620966714 0.792319984919955 GO:0000774 adenyl-nucleotide exchange factor activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0004559 alpha-mannosidase activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0004953 icosanoid receptor activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0008242 omega peptidase activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0008252 nucleotidase activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0016846 carbon-sulfur lyase activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0017081 chloride channel regulator activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0030553 cGMP binding 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0051371 muscle alpha-actinin binding 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0120283 protein serine/threonine kinase binding 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0140776 protein-containing complex destabilizing activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0141050 histone H3K deacetylase activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0141051 histone H4K deacetylase activity 1/768 15/18639 0.0666666666666667 1.61796875 0.46815080936822 0.792319984919955 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/768 86/18639 0.0465116279069767 1.12881540697674 0.475434355997156 0.803202385984424 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/768 39/18639 0.0512820512820513 1.24459134615385 0.481620559938464 0.806972833129613 GO:0000062 fatty-acyl-CoA binding 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0004707 MAP kinase activity 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0015923 mannosidase activity 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0017070 U6 snRNA binding 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0022858 alanine transmembrane transporter activity 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0034450 ubiquitin-ubiquitin ligase activity 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0140327 flippase activity 1/768 16/18639 0.0625 1.516845703125 0.490082734755097 0.806972833129613 GO:0140789 histone phosphatase activity 6/768 136/18639 0.0441176470588235 1.07071461397059 0.491282734959348 0.806972833129613 GO:0004536 DNA nuclease activity 3/768 64/18639 0.046875 1.13763427734375 0.494427184893744 0.806972833129613 GO:0004177 aminopeptidase activity 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0004532 RNA exonuclease activity 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0030331 nuclear estrogen receptor binding 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0050997 quaternary ammonium group binding 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0071855 neuropeptide receptor binding 2/768 40/18639 0.05 1.2134765625 0.495019314280944 0.806972833129613 GO:0003727 single-stranded RNA binding 4/768 89/18639 0.0449438202247191 1.0907654494382 0.502238491229502 0.806972833129613 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/768 89/18639 0.0449438202247191 1.0907654494382 0.502238491229502 0.806972833129613 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/768 89/18639 0.0449438202247191 1.0907654494382 0.502238491229502 0.806972833129613 GO:0038024 cargo receptor activity 3/768 65/18639 0.0461538461538462 1.12013221153846 0.504829949968131 0.806972833129613 GO:0160215 deacylase activity 3/768 65/18639 0.0461538461538462 1.12013221153846 0.504829949968131 0.806972833129613 GO:0008234 cysteine-type peptidase activity 8/768 187/18639 0.0427807486631016 1.03826871657754 0.507812514878672 0.806972833129613 GO:0042169 SH2 domain binding 2/768 41/18639 0.0487804878048781 1.18387957317073 0.508195649164647 0.806972833129613 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/768 41/18639 0.0487804878048781 1.18387957317073 0.508195649164647 0.806972833129613 GO:0140318 protein transporter activity 2/768 41/18639 0.0487804878048781 1.18387957317073 0.508195649164647 0.806972833129613 GO:0140793 histone H2AXY142 phosphatase activity 4/768 90/18639 0.0444444444444444 1.07864583333333 0.511040002318771 0.806972833129613 GO:0004659 prenyltransferase activity 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0005092 GDP-dissociation inhibitor activity 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0016805 dipeptidase activity 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0017110 nucleoside diphosphate phosphatase activity 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0032183 SUMO binding 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0036041 long-chain fatty acid binding 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0045125 bioactive lipid receptor activity 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:1901567 fatty acid derivative binding 1/768 17/18639 0.0588235294117647 1.42761948529412 0.51111137996307 0.806972833129613 GO:0019894 kinesin binding 2/768 42/18639 0.0476190476190476 1.15569196428571 0.521145128341835 0.819555312310565 GO:0035198 miRNA binding 2/768 42/18639 0.0476190476190476 1.15569196428571 0.521145128341835 0.819555312310565 GO:0015631 tubulin binding 16/768 385/18639 0.0415584415584416 1.0086038961039 0.522356352579153 0.819555312310565 GO:0000400 four-way junction DNA binding 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0008308 voltage-gated monoatomic anion channel activity 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0008525 phosphatidylcholine transporter activity 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0015172 acidic amino acid transmembrane transporter activity 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0017075 syntaxin-1 binding 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0031690 adrenergic receptor binding 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0034185 apolipoprotein binding 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0035615 clathrin adaptor activity 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0050811 GABA receptor binding 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:1990381 ubiquitin-specific protease binding 1/768 18/18639 0.0555555555555556 1.34830729166667 0.531273900647656 0.819555312310565 GO:0002039 p53 binding 3/768 69/18639 0.0434782608695652 1.05519701086957 0.545287236577371 0.837027748589574 GO:0016790 thiolester hydrolase activity 2/768 44/18639 0.0454545454545455 1.10316051136364 0.546349430196057 0.837027748589574 GO:0008381 mechanosensitive monoatomic ion channel activity 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0015245 fatty acid transmembrane transporter activity 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0016918 retinal binding 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0042577 lipid phosphatase activity 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0046624 sphingolipid transporter activity 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0097001 ceramide binding 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0120227 acyl-CoA binding 1/768 19/18639 0.0526315789473684 1.27734375 0.550605926011633 0.837027748589574 GO:0046915 transition metal ion transmembrane transporter activity 2/768 45/18639 0.0444444444444444 1.07864583333333 0.55859887875596 0.847408648373979 GO:0015108 chloride transmembrane transporter activity 5/768 121/18639 0.0413223140495868 1.00287319214876 0.561199294369936 0.847408648373979 GO:0015085 calcium ion transmembrane transporter activity 6/768 147/18639 0.0408163265306122 0.990593112244898 0.56762791902085 0.847408648373979 GO:0042393 histone binding 10/768 247/18639 0.0404858299595142 0.982572115384615 0.568056566562392 0.847408648373979 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/768 122/18639 0.040983606557377 0.994652920081967 0.568565882461941 0.847408648373979 GO:0000339 RNA cap binding 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0001972 retinoic acid binding 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0016004 phospholipase activator activity 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0030627 pre-mRNA 5'-splice site binding 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0030742 GTP-dependent protein binding 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0052745 inositol phosphate phosphatase activity 1/768 20/18639 0.05 1.2134765625 0.569141621437146 0.847408648373979 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/768 46/18639 0.0434782608695652 1.05519701086957 0.570610625704715 0.848253710565777 GO:0042379 chemokine receptor binding 3/768 72/18639 0.0416666666666667 1.01123046875 0.574330901785601 0.852437505647083 GO:0004725 protein tyrosine phosphatase activity 4/768 98/18639 0.0408163265306122 0.990593112244898 0.578667751786353 0.857521818001509 GO:0140359 ABC-type transporter activity 2/768 47/18639 0.0425531914893617 1.0327460106383 0.582383439835902 0.857586704016559 GO:0004721 phosphoprotein phosphatase activity 7/768 175/18639 0.04 0.97078125 0.585683074814707 0.857586704016559 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0005248 voltage-gated sodium channel activity 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0008373 sialyltransferase activity 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0035613 RNA stem-loop binding 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0051428 peptide hormone receptor binding 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0070182 DNA polymerase binding 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0140312 cargo adaptor activity 1/768 21/18639 0.0476190476190476 1.15569196428571 0.586913748551184 0.857586704016559 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/768 48/18639 0.0416666666666667 1.01123046875 0.59391659420924 0.865132376394575 GO:0140693 molecular condensate scaffold activity 2/768 48/18639 0.0416666666666667 1.01123046875 0.59391659420924 0.865132376394575 GO:0019003 GDP binding 3/768 75/18639 0.04 0.97078125 0.602188938315288 0.868143974094935 GO:0004407 histone deacetylase activity 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0033558 protein lysine deacetylase activity 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0033691 sialic acid binding 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0034062 5'-3' RNA polymerase activity 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0061133 endopeptidase activator activity 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0097747 RNA polymerase activity 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0140517 protein-RNA adaptor activity 1/768 22/18639 0.0454545454545455 1.10316051136364 0.603953722829447 0.868143974094935 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 9/768 229/18639 0.0393013100436681 0.953824372270742 0.605082776382191 0.868143974094935 GO:0016763 pentosyltransferase activity 2/768 49/18639 0.0408163265306122 0.990593112244898 0.605209826786692 0.868143974094935 GO:0003774 cytoskeletal motor activity 6/768 153/18639 0.0392156862745098 0.951746323529412 0.606846609908111 0.86916691008148 GO:0031490 chromatin DNA binding 5/768 128/18639 0.0390625 0.948028564453125 0.611370908032586 0.872487982627592 GO:0004674 protein serine/threonine kinase activity 17/768 433/18639 0.0392609699769053 0.952845337759815 0.616243625361906 0.872487982627592 GO:0005006 epidermal growth factor receptor activity 2/768 50/18639 0.04 0.97078125 0.616263303449285 0.872487982627592 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0005158 insulin receptor binding 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0005212 structural constituent of eye lens 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0005283 amino acid:sodium symporter activity 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0008171 O-methyltransferase activity 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0042171 lysophosphatidic acid acyltransferase activity 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0043274 phospholipase binding 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0071617 lysophospholipid acyltransferase activity 1/768 23/18639 0.0434782608695652 1.05519701086957 0.620291668839383 0.872487982627592 GO:0005010 insulin-like growth factor receptor activity 2/768 51/18639 0.0392156862745098 0.951746323529412 0.627077583265711 0.873286090843039 GO:0016597 amino acid binding 2/768 51/18639 0.0392156862745098 0.951746323529412 0.627077583265711 0.873286090843039 GO:0030544 Hsp70 protein binding 2/768 51/18639 0.0392156862745098 0.951746323529412 0.627077583265711 0.873286090843039 GO:0004518 nuclease activity 8/768 209/18639 0.0382775119617225 0.928977272727273 0.634163079658963 0.873286090843039 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0004622 lysophospholipase activity 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0005315 phosphate transmembrane transporter activity 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0015295 solute:proton symporter activity 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0019957 C-C chemokine binding 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0035035 histone acetyltransferase binding 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0050699 WW domain binding 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0060229 lipase activator activity 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0070840 dynein complex binding 1/768 24/18639 0.0416666666666667 1.01123046875 0.635956473219021 0.873286090843039 GO:0030695 GTPase regulator activity 19/768 489/18639 0.0388548057259714 0.942987921779141 0.637188186113762 0.873286090843039 GO:0030159 signaling receptor complex adaptor activity 2/768 52/18639 0.0384615384615385 0.933443509615385 0.637653585890313 0.873286090843039 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/768 132/18639 0.0378787878787879 0.919300426136364 0.638491849628067 0.873286090843039 GO:0000149 SNARE binding 4/768 106/18639 0.0377358490566038 0.915831367924528 0.640631001679379 0.873767040088692 GO:0060589 nucleoside-triphosphatase regulator activity 19/768 490/18639 0.0387755102040816 0.941063456632653 0.64070059262614 0.873767040088692 GO:0000049 tRNA binding 3/768 80/18639 0.0375 0.910107421875 0.645873524912968 0.878864076313785 GO:0140296 general transcription initiation factor binding 2/768 53/18639 0.0377358490566038 0.915831367924528 0.647992560974309 0.878864076313785 GO:0001848 complement binding 1/768 25/18639 0.04 0.97078125 0.650975835484281 0.878864076313785 GO:0003707 nuclear steroid receptor activity 1/768 25/18639 0.04 0.97078125 0.650975835484281 0.878864076313785 GO:0017056 structural constituent of nuclear pore 1/768 25/18639 0.04 0.97078125 0.650975835484281 0.878864076313785 GO:0047617 fatty acyl-CoA hydrolase activity 1/768 25/18639 0.04 0.97078125 0.650975835484281 0.878864076313785 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/768 25/18639 0.04 0.97078125 0.650975835484281 0.878864076313785 GO:0005261 monoatomic cation channel activity 13/768 341/18639 0.0381231671554252 0.925231396627566 0.652577274967487 0.879763919404592 GO:0051287 NAD binding 2/768 54/18639 0.037037037037037 0.898871527777778 0.65809605948004 0.884349031165517 GO:0008083 growth factor activity 6/768 162/18639 0.037037037037037 0.898871527777778 0.661815557576886 0.884349031165517 GO:0046982 protein heterodimerization activity 14/768 369/18639 0.037940379403794 0.920795223577236 0.662413595759123 0.884349031165517 GO:0016779 nucleotidyltransferase activity 5/768 136/18639 0.0367647058823529 0.892262178308823 0.664411934328496 0.884349031165517 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/768 26/18639 0.0384615384615385 0.933443509615385 0.665376316753651 0.884349031165517 GO:0005112 Notch binding 1/768 26/18639 0.0384615384615385 0.933443509615385 0.665376316753651 0.884349031165517 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/768 26/18639 0.0384615384615385 0.933443509615385 0.665376316753651 0.884349031165517 GO:0008157 protein phosphatase 1 binding 1/768 26/18639 0.0384615384615385 0.933443509615385 0.665376316753651 0.884349031165517 GO:0016289 acyl-CoA hydrolase activity 1/768 26/18639 0.0384615384615385 0.933443509615385 0.665376316753651 0.884349031165517 GO:0043548 phosphatidylinositol 3-kinase binding 1/768 26/18639 0.0384615384615385 0.933443509615385 0.665376316753651 0.884349031165517 GO:1902936 phosphatidylinositol bisphosphate binding 4/768 111/18639 0.036036036036036 0.874577702702703 0.676192628794866 0.891368991176383 GO:0170055 lipid transmembrane transporter activity 2/768 56/18639 0.0357142857142857 0.866768973214286 0.677604177537233 0.891368991176383 GO:0015103 inorganic anion transmembrane transporter activity 6/768 165/18639 0.0363636363636364 0.882528409090909 0.6790300835081 0.891368991176383 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/768 27/18639 0.037037037037037 0.898871527777778 0.679183386475523 0.891368991176383 GO:0005044 scavenger receptor activity 1/768 27/18639 0.037037037037037 0.898871527777778 0.679183386475523 0.891368991176383 GO:0005385 zinc ion transmembrane transporter activity 1/768 27/18639 0.037037037037037 0.898871527777778 0.679183386475523 0.891368991176383 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/768 27/18639 0.037037037037037 0.898871527777778 0.679183386475523 0.891368991176383 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/768 27/18639 0.037037037037037 0.898871527777778 0.679183386475523 0.891368991176383 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/768 27/18639 0.037037037037037 0.898871527777778 0.679183386475523 0.891368991176383 GO:0016866 intramolecular transferase activity 1/768 28/18639 0.0357142857142857 0.866768973214286 0.692421467239912 0.905030626725921 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/768 28/18639 0.0357142857142857 0.866768973214286 0.692421467239912 0.905030626725921 GO:0016791 phosphatase activity 10/768 273/18639 0.0366300366300366 0.888993818681319 0.69247826912079 0.905030626725921 GO:0008408 3'-5' exonuclease activity 2/768 58/18639 0.0344827586206897 0.836880387931034 0.696195393999937 0.907368235116262 GO:0061980 regulatory RNA binding 2/768 58/18639 0.0344827586206897 0.836880387931034 0.696195393999937 0.907368235116262 GO:0020037 heme binding 5/768 142/18639 0.0352112676056338 0.854560959507042 0.700960287590158 0.908971879586955 GO:0005416 amino acid:monoatomic cation symporter activity 1/768 29/18639 0.0344827586206897 0.836880387931034 0.705113977753035 0.908971879586955 GO:0035250 UDP-galactosyltransferase activity 1/768 29/18639 0.0344827586206897 0.836880387931034 0.705113977753035 0.908971879586955 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/768 29/18639 0.0344827586206897 0.836880387931034 0.705113977753035 0.908971879586955 GO:0051861 glycolipid binding 1/768 29/18639 0.0344827586206897 0.836880387931034 0.705113977753035 0.908971879586955 GO:0106222 lncRNA binding 1/768 29/18639 0.0344827586206897 0.836880387931034 0.705113977753035 0.908971879586955 GO:0004879 nuclear receptor activity 2/768 59/18639 0.0338983050847458 0.822695974576271 0.705153530391581 0.908971879586955 GO:0070888 E-box binding 2/768 59/18639 0.0338983050847458 0.822695974576271 0.705153530391581 0.908971879586955 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/768 60/18639 0.0333333333333333 0.808984375 0.713890431637974 0.91771980351275 GO:0098531 ligand-modulated transcription factor activity 2/768 60/18639 0.0333333333333333 0.808984375 0.713890431637974 0.91771980351275 GO:0016769 transferase activity, transferring nitrogenous groups 1/768 30/18639 0.0333333333333333 0.808984375 0.717283374049955 0.920701538336912 GO:0008194 UDP-glycosyltransferase activity 5/768 145/18639 0.0344827586206897 0.836880387931034 0.718166768479589 0.920701538336912 GO:0140030 modification-dependent protein binding 6/768 173/18639 0.0346820809248555 0.841717846820809 0.722098580864622 0.923623583334805 GO:0016836 hydro-lyase activity 2/768 61/18639 0.0327868852459016 0.795722336065574 0.722409093872919 0.923623583334805 GO:0005164 tumor necrosis factor receptor binding 1/768 31/18639 0.032258064516129 0.78288810483871 0.728951189017424 0.927819994452848 GO:0016411 acylglycerol O-acyltransferase activity 1/768 31/18639 0.032258064516129 0.78288810483871 0.728951189017424 0.927819994452848 GO:0047499 calcium-independent phospholipase A2 activity 1/768 31/18639 0.032258064516129 0.78288810483871 0.728951189017424 0.927819994452848 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/768 91/18639 0.032967032967033 0.800094436813187 0.729635277253037 0.927819994452848 GO:0052689 carboxylic ester hydrolase activity 3/768 92/18639 0.0326086956521739 0.791397758152174 0.736417620882522 0.934858958588834 GO:0004540 RNA nuclease activity 4/768 121/18639 0.0330578512396694 0.802298553719008 0.73975227642197 0.934858958588834 GO:0008509 monoatomic anion transmembrane transporter activity 5/768 149/18639 0.0335570469798658 0.81441380033557 0.739996263293561 0.934858958588834 GO:0008378 galactosyltransferase activity 1/768 32/18639 0.03125 0.7584228515625 0.740138070296154 0.934858958588834 GO:0047498 calcium-dependent phospholipase A2 activity 1/768 32/18639 0.03125 0.7584228515625 0.740138070296154 0.934858958588834 GO:0000510 H3-H4 histone complex chaperone activity 5/768 151/18639 0.033112582781457 0.803626862582781 0.750435874727134 0.941182280377602 GO:0140584 chromatin extrusion motor activity 5/768 151/18639 0.033112582781457 0.803626862582781 0.750435874727134 0.941182280377602 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/768 151/18639 0.033112582781457 0.803626862582781 0.750435874727134 0.941182280377602 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/768 151/18639 0.033112582781457 0.803626862582781 0.750435874727134 0.941182280377602 GO:0019239 deaminase activity 1/768 33/18639 0.0303030303030303 0.735440340909091 0.750863816628855 0.941182280377602 GO:0015616 DNA translocase activity 5/768 152/18639 0.0328947368421053 0.79833984375 0.755537584202581 0.941182280377602 GO:0046906 tetrapyrrole binding 5/768 152/18639 0.0328947368421053 0.79833984375 0.755537584202581 0.941182280377602 GO:0140674 ATP-dependent histone chaperone activity 5/768 152/18639 0.0328947368421053 0.79833984375 0.755537584202581 0.941182280377602 GO:0005216 monoatomic ion channel activity 16/768 448/18639 0.0357142857142857 0.866768973214286 0.756366580782778 0.941182280377602 GO:0003730 mRNA 3'-UTR binding 9/768 262/18639 0.0343511450381679 0.833686187977099 0.75670535360063 0.941182280377602 GO:0061775 cohesin loader activity 5/768 153/18639 0.0326797385620915 0.79312193627451 0.760560927928745 0.941182280377602 GO:0008175 tRNA methyltransferase activity 1/768 34/18639 0.0294117647058824 0.713809742647059 0.761147412717699 0.941182280377602 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/768 34/18639 0.0294117647058824 0.713809742647059 0.761147412717699 0.941182280377602 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/768 34/18639 0.0294117647058824 0.713809742647059 0.761147412717699 0.941182280377602 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/768 34/18639 0.0294117647058824 0.713809742647059 0.761147412717699 0.941182280377602 GO:0090482 vitamin transmembrane transporter activity 1/768 34/18639 0.0294117647058824 0.713809742647059 0.761147412717699 0.941182280377602 GO:0004386 helicase activity 5/768 155/18639 0.032258064516129 0.78288810483871 0.770373826851824 0.948389079680774 GO:0004623 phospholipase A2 activity 1/768 35/18639 0.0285714285714286 0.693415178571429 0.771007062652276 0.948389079680774 GO:0005343 organic acid:sodium symporter activity 1/768 35/18639 0.0285714285714286 0.693415178571429 0.771007062652276 0.948389079680774 GO:0061631 ubiquitin conjugating enzyme activity 1/768 35/18639 0.0285714285714286 0.693415178571429 0.771007062652276 0.948389079680774 GO:0004519 endonuclease activity 4/768 127/18639 0.031496062992126 0.76439468503937 0.773093703123975 0.948476107744017 GO:0042826 histone deacetylase binding 4/768 127/18639 0.031496062992126 0.76439468503937 0.773093703123975 0.948476107744017 GO:1901981 phosphatidylinositol phosphate binding 6/768 185/18639 0.0324324324324324 0.787119932432432 0.778853208000085 0.951312265376346 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/768 268/18639 0.0335820895522388 0.815021571828358 0.779316232780625 0.951312265376346 GO:0004190 aspartic-type endopeptidase activity 1/768 36/18639 0.0277777777777778 0.674153645833333 0.780460221966566 0.951312265376346 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/768 36/18639 0.0277777777777778 0.674153645833333 0.780460221966566 0.951312265376346 GO:0045505 dynein intermediate chain binding 1/768 36/18639 0.0277777777777778 0.674153645833333 0.780460221966566 0.951312265376346 GO:0140658 ATP-dependent chromatin remodeler activity 5/768 158/18639 0.0316455696202532 0.768023140822785 0.784514475353297 0.955016974524518 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/768 130/18639 0.0307692307692308 0.746754807692308 0.788459257782386 0.958579020120446 GO:0070001 aspartic-type peptidase activity 1/768 37/18639 0.027027027027027 0.655933277027027 0.789523628381106 0.95863449587951 GO:0005262 calcium channel activity 4/768 131/18639 0.0305343511450382 0.741054389312977 0.793392704854095 0.961056465027373 GO:0003689 DNA clamp loader activity 5/768 160/18639 0.03125 0.7584228515625 0.793560970591147 0.961056465027373 GO:0140299 molecular sensor activity 2/768 71/18639 0.028169014084507 0.683648767605634 0.796325412151593 0.963164797987981 GO:0035402 histone H3T11 kinase activity 8/768 247/18639 0.0323886639676113 0.786057692307692 0.802816619062667 0.969442515296806 GO:0000217 DNA secondary structure binding 1/768 39/18639 0.0256410256410256 0.622295673076923 0.806544720003822 0.969442515296806 GO:0008017 microtubule binding 9/768 276/18639 0.0326086956521739 0.791397758152174 0.807048204086826 0.969442515296806 GO:0043539 protein serine/threonine kinase activator activity 2/768 73/18639 0.0273972602739726 0.664918664383562 0.808834786604621 0.969442515296806 GO:0140713 histone chaperone activity 5/768 164/18639 0.0304878048780488 0.739924733231707 0.810759218057353 0.969442515296806 GO:0001217 DNA-binding transcription repressor activity 9/768 278/18639 0.0323741007194245 0.785704249100719 0.813556292658247 0.969442515296806 GO:0061791 GTPase motor activity 1/768 40/18639 0.025 0.60673828125 0.814532550919793 0.969442515296806 GO:1990606 membrane scission GTPase motor activity 1/768 40/18639 0.025 0.60673828125 0.814532550919793 0.969442515296806 GO:0035064 methylated histone binding 2/768 74/18639 0.027027027027027 0.655933277027027 0.814829149358085 0.969442515296806 GO:0106310 protein serine kinase activity 12/768 361/18639 0.0332409972299169 0.806743421052632 0.814947067943622 0.969442515296806 GO:0042578 phosphoric ester hydrolase activity 12/768 363/18639 0.0330578512396694 0.802298553719008 0.820538480336474 0.969442515296806 GO:0001530 lipopolysaccharide binding 1/768 41/18639 0.024390243902439 0.591939786585366 0.822190973463672 0.969442515296806 GO:0001727 lipid kinase activity 1/768 41/18639 0.024390243902439 0.591939786585366 0.822190973463672 0.969442515296806 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/768 41/18639 0.024390243902439 0.591939786585366 0.822190973463672 0.969442515296806 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/768 41/18639 0.024390243902439 0.591939786585366 0.822190973463672 0.969442515296806 GO:0140034 methylation-dependent protein binding 2/768 76/18639 0.0263157894736842 0.638671875 0.826315759468403 0.969442515296806 GO:0004843 cysteine-type deubiquitinase activity 3/768 108/18639 0.0277777777777778 0.674153645833333 0.827452505277842 0.969442515296806 GO:0004520 DNA endonuclease activity 1/768 42/18639 0.0238095238095238 0.577845982142857 0.829533555052009 0.969442515296806 GO:0003724 RNA helicase activity 2/768 77/18639 0.025974025974026 0.630377435064935 0.831815379449709 0.969442515296806 GO:0051540 metal cluster binding 2/768 77/18639 0.025974025974026 0.630377435064935 0.831815379449709 0.969442515296806 GO:0035091 phosphatidylinositol binding 9/768 284/18639 0.0316901408450704 0.769104863556338 0.832083754271758 0.969442515296806 GO:0004620 phospholipase activity 3/768 109/18639 0.0275229357798165 0.66796875 0.832127533230747 0.969442515296806 GO:0005245 voltage-gated calcium channel activity 1/768 43/18639 0.0232558139534884 0.564407703488372 0.836573304996627 0.969442515296806 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/768 43/18639 0.0232558139534884 0.564407703488372 0.836573304996627 0.969442515296806 GO:0008186 ATP-dependent activity, acting on RNA 2/768 79/18639 0.0253164556962025 0.614418512658228 0.842345518491586 0.969442515296806 GO:0043014 alpha-tubulin binding 1/768 44/18639 0.0227272727272727 0.551580255681818 0.84332269743385 0.969442515296806 GO:0003823 antigen binding 5/768 174/18639 0.028735632183908 0.697400323275862 0.848767822264178 0.969442515296806 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/768 45/18639 0.0222222222222222 0.539322916666667 0.849793693312892 0.969442515296806 GO:0008009 chemokine activity 1/768 45/18639 0.0222222222222222 0.539322916666667 0.849793693312892 0.969442515296806 GO:0003714 transcription corepressor activity 6/768 204/18639 0.0294117647058824 0.713809742647059 0.85017131149476 0.969442515296806 GO:0015101 organic cation transmembrane transporter activity 2/768 81/18639 0.0246913580246914 0.599247685185185 0.852274215571164 0.969442515296806 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/768 46/18639 0.0217391304347826 0.527598505434783 0.855997761481963 0.969442515296806 GO:0035401 histone H3Y41 kinase activity 3/768 115/18639 0.0260869565217391 0.633118206521739 0.857946555437011 0.969442515296806 GO:0101005 deubiquitinase activity 3/768 115/18639 0.0260869565217391 0.633118206521739 0.857946555437011 0.969442515296806 GO:0140801 histone H2AXY142 kinase activity 3/768 115/18639 0.0260869565217391 0.633118206521739 0.857946555437011 0.969442515296806 GO:0001784 phosphotyrosine residue binding 1/768 47/18639 0.0212765957446809 0.516373005319149 0.861945898909051 0.969442515296806 GO:0140938 histone H3 methyltransferase activity 1/768 47/18639 0.0212765957446809 0.516373005319149 0.861945898909051 0.969442515296806 GO:0004527 exonuclease activity 2/768 84/18639 0.0238095238095238 0.577845982142857 0.866101373357038 0.969442515296806 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/768 48/18639 0.0208333333333333 0.505615234375 0.867648650072877 0.969442515296806 GO:0008094 ATP-dependent activity, acting on DNA 6/768 210/18639 0.0285714285714286 0.693415178571429 0.868358893518882 0.969442515296806 GO:0005004 GPI-linked ephrin receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0005008 hepatocyte growth factor receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0005009 insulin receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0005011 macrophage colony-stimulating factor receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0005020 stem cell factor receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0008288 boss receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0036332 placental growth factor receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0038062 protein tyrosine kinase collagen receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0060175 brain-derived neurotrophic factor receptor activity 1/768 49/18639 0.0204081632653061 0.495296556122449 0.873116125558006 0.969442515296806 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/768 243/18639 0.0288065843621399 0.699122299382716 0.877519431993381 0.969442515296806 GO:0005007 fibroblast growth factor receptor activity 1/768 50/18639 0.02 0.485390625 0.878358019886755 0.969442515296806 GO:0005017 platelet-derived growth factor receptor activity 1/768 50/18639 0.02 0.485390625 0.878358019886755 0.969442515296806 GO:0005019 platelet-derived growth factor beta-receptor activity 1/768 50/18639 0.02 0.485390625 0.878358019886755 0.969442515296806 GO:0032813 tumor necrosis factor receptor superfamily binding 1/768 50/18639 0.02 0.485390625 0.878358019886755 0.969442515296806 GO:0008081 phosphoric diester hydrolase activity 2/768 87/18639 0.0229885057471264 0.55792025862069 0.878731713192271 0.969442515296806 GO:0003697 single-stranded DNA binding 3/768 121/18639 0.0247933884297521 0.601723915289256 0.880221076393249 0.969442515296806 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0004711 ribosomal protein S6 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0035175 histone H3S10 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0035979 histone H2AXS139 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0044022 histone H3S28 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0044023 histone H4S1 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0044024 histone H2AS1 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0044025 histone H2BS14 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0072354 histone H3T3 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0072371 histone H2AS121 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0140823 histone H2BS36 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0140855 histone H3S57 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0140995 histone H2A kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0140997 histone H4 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0140998 histone H2B kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:1990244 histone H2AT120 kinase activity 7/768 245/18639 0.0285714285714286 0.693415178571429 0.882525581383993 0.969442515296806 GO:0005506 iron ion binding 4/768 154/18639 0.025974025974026 0.630377435064935 0.883277989299105 0.969442515296806 GO:0005021 vascular endothelial growth factor receptor activity 1/768 51/18639 0.0196078431372549 0.475873161764706 0.883383628619176 0.969442515296806 GO:0005030 neurotrophin receptor activity 1/768 51/18639 0.0196078431372549 0.475873161764706 0.883383628619176 0.969442515296806 GO:0005272 sodium channel activity 1/768 51/18639 0.0196078431372549 0.475873161764706 0.883383628619176 0.969442515296806 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/768 122/18639 0.0245901639344262 0.59679175204918 0.883616014326756 0.969442515296806 GO:0004677 DNA-dependent protein kinase activity 7/768 246/18639 0.0284552845528455 0.690596417682927 0.884963996429284 0.969442515296806 GO:0140857 histone H3T45 kinase activity 7/768 246/18639 0.0284552845528455 0.690596417682927 0.884963996429284 0.969442515296806 GO:0035403 histone H3T6 kinase activity 7/768 247/18639 0.0283400809716599 0.687800480769231 0.887359961602477 0.970936888218524 GO:0004679 AMP-activated protein kinase activity 7/768 248/18639 0.0282258064516129 0.685027091733871 0.889713972119912 0.971265686991008 GO:0140097 catalytic activity, acting on DNA 10/768 336/18639 0.0297619047619048 0.722307477678571 0.890240954501284 0.971265686991008 GO:0005003 ephrin receptor activity 1/768 53/18639 0.0188679245283019 0.457915683962264 0.89282127443913 0.971265686991008 GO:0005005 transmembrane-ephrin receptor activity 1/768 53/18639 0.0188679245283019 0.457915683962264 0.89282127443913 0.971265686991008 GO:0038064 collagen receptor activity 1/768 53/18639 0.0188679245283019 0.457915683962264 0.89282127443913 0.971265686991008 GO:0019783 ubiquitin-like protein peptidase activity 3/768 127/18639 0.0236220472440945 0.573296013779528 0.899335001151882 0.977221981621155 GO:0030170 pyridoxal phosphate binding 1/768 56/18639 0.0178571428571429 0.433384486607143 0.905566816174591 0.981795371004539 GO:0008236 serine-type peptidase activity 5/768 194/18639 0.0257731958762887 0.625503382731959 0.905931296358624 0.981795371004539 GO:0008276 protein methyltransferase activity 2/768 95/18639 0.0210526315789474 0.5109375 0.907224573945961 0.981795371004539 GO:0016298 lipase activity 3/768 130/18639 0.0230769230769231 0.560066105769231 0.907822881116066 0.981795371004539 GO:0070279 vitamin B6 binding 1/768 57/18639 0.0175438596491228 0.42578125 0.909469559820822 0.981795371004539 GO:0016407 acetyltransferase activity 2/768 96/18639 0.0208333333333333 0.505615234375 0.910310072248482 0.981795371004539 GO:0017171 serine hydrolase activity 5/768 198/18639 0.0252525252525253 0.612866950757576 0.914782361858816 0.981795371004539 GO:0008170 N-methyltransferase activity 2/768 98/18639 0.0204081632653061 0.495296556122449 0.916194786485784 0.981795371004539 GO:0015459 potassium channel regulator activity 1/768 59/18639 0.0169491525423729 0.411347987288136 0.916798413257271 0.981795371004539 GO:0031593 polyubiquitin modification-dependent protein binding 1/768 59/18639 0.0169491525423729 0.411347987288136 0.916798413257271 0.981795371004539 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/768 167/18639 0.0239520958083832 0.581306137724551 0.91725094337364 0.981795371004539 GO:0016829 lyase activity 5/768 200/18639 0.025 0.60673828125 0.918927078622826 0.981795371004539 GO:0001098 basal transcription machinery binding 1/768 60/18639 0.0166666666666667 0.4044921875 0.920237531589801 0.981795371004539 GO:0001099 basal RNA polymerase II transcription machinery binding 1/768 60/18639 0.0166666666666667 0.4044921875 0.920237531589801 0.981795371004539 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/768 60/18639 0.0166666666666667 0.4044921875 0.920237531589801 0.981795371004539 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/768 60/18639 0.0166666666666667 0.4044921875 0.920237531589801 0.981795371004539 GO:0015179 L-amino acid transmembrane transporter activity 1/768 62/18639 0.0161290322580645 0.391444052419355 0.926695689105931 0.987565847620251 GO:0140767 enzyme-substrate adaptor activity 3/768 139/18639 0.0215827338129496 0.523802832733813 0.929534339953649 0.989470377710841 GO:0005096 GTPase activator activity 7/768 271/18639 0.025830258302583 0.626888261070111 0.933425103383757 0.992489290716514 GO:0008173 RNA methyltransferase activity 1/768 67/18639 0.0149253731343284 0.362231809701493 0.940647475460877 0.996789723433204 GO:0016500 protein-hormone receptor activity 1/768 67/18639 0.0149253731343284 0.362231809701493 0.940647475460877 0.996789723433204 GO:0042054 histone methyltransferase activity 1/768 67/18639 0.0149253731343284 0.362231809701493 0.940647475460877 0.996789723433204 GO:0003777 microtubule motor activity 1/768 68/18639 0.0147058823529412 0.356904871323529 0.943101855110137 0.997144770402965 GO:0140223 general transcription initiation factor activity 1/768 68/18639 0.0147058823529412 0.356904871323529 0.943101855110137 0.997144770402965 GO:0016279 protein-lysine N-methyltransferase activity 1/768 69/18639 0.0144927536231884 0.351732336956522 0.945454866540615 0.998510695190481 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/768 70/18639 0.0142857142857143 0.346707589285714 0.947710691123103 0.998651467353685 GO:0016278 lysine N-methyltransferase activity 1/768 70/18639 0.0142857142857143 0.346707589285714 0.947710691123103 0.998651467353685 GO:0019842 vitamin binding 3/768 150/18639 0.02 0.485390625 0.949661615857619 0.999487103984926 GO:0016755 aminoacyltransferase activity 14/768 496/18639 0.0282258064516129 0.685027091733871 0.950628010697671 0.999487103984926 GO:0004521 RNA endonuclease activity 1/768 73/18639 0.0136986301369863 0.332459332191781 0.953934315784299 0.99998679142419 GO:0015294 solute:monoatomic cation symporter activity 2/768 116/18639 0.0172413793103448 0.418440193965517 0.955027973929266 0.99998679142419 GO:0140375 immune receptor activity 3/768 156/18639 0.0192307692307692 0.466721754807692 0.958242019721951 0.99998679142419 GO:0141003 histone H2AX kinase activity 9/768 354/18639 0.0254237288135593 0.617021980932203 0.958283217170497 0.99998679142419 GO:0051536 iron-sulfur cluster binding 1/768 76/18639 0.0131578947368421 0.3193359375 0.959418035495768 0.99998679142419 GO:0045182 translation regulator activity 9/768 356/18639 0.0252808988764045 0.613555565308989 0.960076147755766 0.99998679142419 GO:0140098 catalytic activity, acting on RNA 10/768 387/18639 0.0258397932816537 0.627119670542636 0.960158358671259 0.99998679142419 GO:0140996 histone H3 kinase activity 9/768 357/18639 0.0252100840336134 0.611836922268908 0.960946533963725 0.99998679142419 GO:0035173 histone kinase activity 9/768 360/18639 0.025 0.60673828125 0.963456725848502 0.99998679142419 GO:0008528 G protein-coupled peptide receptor activity 2/768 122/18639 0.0163934426229508 0.397861168032787 0.963604770417555 0.99998679142419 GO:0015370 solute:sodium symporter activity 1/768 79/18639 0.0126582278481013 0.307209256329114 0.964249714019254 0.99998679142419 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/768 484/18639 0.0268595041322314 0.651867574896694 0.964681084114406 0.99998679142419 GO:0001216 DNA-binding transcription activator activity 13/768 491/18639 0.0264765784114053 0.642574147148676 0.969238471521791 0.99998679142419 GO:0001653 peptide receptor activity 2/768 128/18639 0.015625 0.37921142578125 0.970598545358913 0.99998679142419 GO:0008168 methyltransferase activity 4/768 204/18639 0.0196078431372549 0.475873161764706 0.970932436333948 0.99998679142419 GO:0099094 ligand-gated monoatomic cation channel activity 2/768 136/18639 0.0147058823529412 0.356904871323529 0.977935693766652 0.99998679142419 GO:0004252 serine-type endopeptidase activity 3/768 176/18639 0.0170454545454545 0.413685191761364 0.977942913662942 0.99998679142419 GO:0019787 ubiquitin-like protein transferase activity 12/768 479/18639 0.0250521920668058 0.608004958246347 0.979025986128877 0.99998679142419 GO:0016741 transferase activity, transferring one-carbon groups 4/768 215/18639 0.0186046511627907 0.451526162790698 0.979043236304432 0.99998679142419 GO:0140101 catalytic activity, acting on a tRNA 2/768 139/18639 0.0143884892086331 0.349201888489209 0.980201581058008 0.99998679142419 GO:0051213 dioxygenase activity 1/768 93/18639 0.010752688172043 0.260962701612903 0.980219250988754 0.99998679142419 GO:0016410 N-acyltransferase activity 1/768 94/18639 0.0106382978723404 0.258186502659574 0.981038382620407 0.99998679142419 GO:0004896 cytokine receptor activity 1/768 96/18639 0.0104166666666667 0.2528076171875 0.982576410258448 0.99998679142419 GO:0030594 neurotransmitter receptor activity 1/768 97/18639 0.0103092783505155 0.250201353092784 0.983298047367951 0.99998679142419 GO:0015276 ligand-gated monoatomic ion channel activity 3/768 186/18639 0.0161290322580645 0.391444052419355 0.984095171738427 0.99998679142419 GO:0015293 symporter activity 2/768 146/18639 0.0136986301369863 0.332459332191781 0.984646022847326 0.99998679142419 GO:0022834 ligand-gated channel activity 3/768 188/18639 0.0159574468085106 0.387279753989362 0.985110602126994 0.99998679142419 GO:0015171 amino acid transmembrane transporter activity 1/768 102/18639 0.00980392156862745 0.237936580882353 0.986482383508606 0.99998679142419 GO:0004497 monooxygenase activity 1/768 106/18639 0.00943396226415094 0.228957841981132 0.988587305444332 0.99998679142419 GO:0004842 ubiquitin-protein transferase activity 10/768 449/18639 0.022271714922049 0.540524081291759 0.990213650186305 0.99998679142419 GO:0015081 sodium ion transmembrane transporter activity 2/768 164/18639 0.0121951219512195 0.295969893292683 0.992078515022769 0.99998679142419 GO:0005244 voltage-gated monoatomic ion channel activity 2/768 173/18639 0.0115606936416185 0.280572615606936 0.994332155449963 0.99998679142419 GO:0022832 voltage-gated channel activity 2/768 175/18639 0.0114285714285714 0.277366071428571 0.994740177412792 0.99998679142419 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/768 181/18639 0.0110497237569061 0.268171616022099 0.995799078804688 0.99998679142419 GO:0046873 metal ion transmembrane transporter activity 9/768 450/18639 0.02 0.485390625 0.995880363375658 0.99998679142419 GO:0015297 antiporter activity 1/768 135/18639 0.00740740740740741 0.179774305555556 0.996658499291709 0.99998679142419 GO:0046943 carboxylic acid transmembrane transporter activity 2/768 188/18639 0.0106382978723404 0.258186502659574 0.996772038537424 0.99998679142419 GO:0005125 cytokine activity 3/768 234/18639 0.0128205128205128 0.311147836538462 0.99687826911372 0.99998679142419 GO:0061630 ubiquitin protein ligase activity 6/768 353/18639 0.0169971671388102 0.412513279036827 0.996884719419052 0.99998679142419 GO:0005342 organic acid transmembrane transporter activity 2/768 189/18639 0.0105820105820106 0.256820436507937 0.996891581934442 0.99998679142419 GO:0022836 gated channel activity 5/768 318/18639 0.0157232704402516 0.381596403301887 0.997151773395359 0.99998679142419 GO:0022843 voltage-gated monoatomic cation channel activity 1/768 143/18639 0.00699300699300699 0.169717001748252 0.997619689700106 0.99998679142419 GO:0061659 ubiquitin-like protein ligase activity 6/768 372/18639 0.0161290322580645 0.391444052419355 0.998233146286279 0.99998679142419 GO:0015291 secondary active transmembrane transporter activity 3/768 287/18639 0.0104529616724739 0.253688479965157 0.99952541584972 0.99998679142419 GO:0008514 organic anion transmembrane transporter activity 2/768 269/18639 0.00743494423791822 0.180442611524164 0.999857784205894 0.99998679142419 GO:0030371 translation repressor activity 2/768 329/18639 0.0060790273556231 0.1475351443769 0.99998679142419 0.99998679142419