ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005131 growth hormone receptor binding 4/91 10/18639 0.4 81.9296703296703 1.09163502931117e-07 4.14821311138243e-05 GO:0005179 hormone activity 7/91 132/18639 0.053030303030303 10.8618881118881 3.75935827085139e-06 0.000714278071461765 GO:0051427 hormone receptor binding 4/91 34/18639 0.117647058823529 24.0969618616677 2.20407660584788e-05 0.00279183036740731 GO:0030215 semaphorin receptor binding 3/91 24/18639 0.125 25.603021978022 0.000211540302582683 0.0200963287453549 GO:0045499 chemorepellent activity 3/91 28/18639 0.107142857142857 21.9454474097331 0.000337590816186926 0.0256569020302064 GO:0061134 peptidase regulator activity 6/91 226/18639 0.0265486725663717 5.43780997763299 0.000840601236908415 0.0509272625965555 GO:0005178 integrin binding 5/91 161/18639 0.031055900621118 6.36099924919801 0.0011557520332735 0.0509272625965555 GO:0008083 growth factor activity 5/91 162/18639 0.0308641975308642 6.32173382173382 0.00118802509759277 0.0509272625965555 GO:0004867 serine-type endopeptidase inhibitor activity 4/91 95/18639 0.0421052631578947 8.62417582417582 0.00120617200886579 0.0509272625965555 GO:0030414 peptidase inhibitor activity 5/91 169/18639 0.029585798816568 6.05988685870343 0.00143297299391683 0.0544529737688395 GO:0031994 insulin-like growth factor I binding 2/91 13/18639 0.153846153846154 31.5114116652578 0.00177562325830236 0.0613397125595359 GO:0030159 signaling receptor complex adaptor activity 3/91 52/18639 0.0576923076923077 11.8167793744717 0.00209280176468648 0.0662720558817385 GO:0005520 insulin-like growth factor binding 2/91 19/18639 0.105263157894737 21.5604395604396 0.00381930086163516 0.107266682556237 GO:0038024 cargo receptor activity 3/91 65/18639 0.0461538461538462 9.45342349957735 0.00395193040996662 0.107266682556237 GO:0045296 cadherin binding 6/91 334/18639 0.0179640718562874 3.67947621241034 0.00589436697373934 0.14932396333473 GO:0004866 endopeptidase inhibitor activity 4/91 161/18639 0.0248447204968944 5.08879939935841 0.00801025413087649 0.183419572233403 GO:0097718 disordered domain specific binding 2/91 28/18639 0.0714285714285714 14.6302982731554 0.00820561244202066 0.183419572233403 GO:0005201 extracellular matrix structural constituent 4/91 168/18639 0.0238095238095238 4.87676609105181 0.00927076199493251 0.195716086559686 GO:0042562 hormone binding 3/91 94/18639 0.0319148936170213 6.53694178162263 0.0109592675599287 0.219185351198574 GO:0061135 endopeptidase regulator activity 4/91 184/18639 0.0217391304347826 4.4526994744386 0.0126204762784398 0.239789049290356 GO:0005109 frizzled binding 2/91 38/18639 0.0526315789473684 10.7802197802198 0.0147870001131362 0.250875915998552 GO:0008013 beta-catenin binding 3/91 106/18639 0.0283018867924528 5.79691063653328 0.0151282565645542 0.250875915998552 GO:0001664 G protein-coupled receptor binding 5/91 297/18639 0.0168350168350168 3.44821844821845 0.0151845949157018 0.250875915998552 GO:0004857 enzyme inhibitor activity 6/91 416/18639 0.0144230769230769 2.95419484361792 0.0161988068351035 0.256481108222472 GO:0017124 SH3 domain binding 3/91 115/18639 0.0260869565217391 5.34323936932633 0.0187664196782295 0.285249579109089 GO:0003924 GTPase activity 5/91 331/18639 0.0151057401812689 3.09402078284254 0.0230583011849524 0.336156037168522 GO:0035591 signaling adaptor activity 3/91 129/18639 0.0232558139534884 4.76335292614362 0.0253084238976355 0.336156037168522 GO:0005010 insulin-like growth factor receptor activity 2/91 51/18639 0.0392156862745098 8.03232062055591 0.0257459554737535 0.336156037168522 GO:0019838 growth factor binding 3/91 136/18639 0.0220588235294118 4.5181803490627 0.0289831247715432 0.336156037168522 GO:0170055 lipid transmembrane transporter activity 2/91 56/18639 0.0357142857142857 7.31514913657771 0.0306143616372206 0.336156037168522 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 6/91 484/18639 0.012396694214876 2.53914267550631 0.0311383188986649 0.336156037168522 GO:0001216 DNA-binding transcription activator activity 6/91 491/18639 0.0122199592668024 2.50294308542781 0.0330610006959913 0.336156037168522 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/91 60/18639 0.0333333333333333 6.82747252747253 0.0347497485121332 0.336156037168522 GO:0003713 transcription coactivator activity 4/91 256/18639 0.015625 3.20037774725275 0.0367328313702077 0.336156037168522 GO:0016500 protein-hormone receptor activity 2/91 67/18639 0.0298507462686567 6.1141545022142 0.0424709184252882 0.336156037168522 GO:0005126 cytokine receptor binding 4/91 275/18639 0.0145454545454545 2.97926073926074 0.0457439536475693 0.336156037168522 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/91 10/18639 0.1 20.4824175824176 0.0477748606318629 0.336156037168522 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/91 10/18639 0.1 20.4824175824176 0.0477748606318629 0.336156037168522 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/91 10/18639 0.1 20.4824175824176 0.0477748606318629 0.336156037168522 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/91 10/18639 0.1 20.4824175824176 0.0477748606318629 0.336156037168522 GO:0000099 sulfur amino acid transmembrane transporter activity 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0008503 benzodiazepine receptor activity 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0015173 aromatic amino acid transmembrane transporter activity 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0034056 estrogen response element binding 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0042608 T cell receptor binding 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0050786 RAGE receptor binding 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0097493 structural molecule activity conferring elasticity 1/91 11/18639 0.0909090909090909 18.6203796203796 0.052426344215657 0.336156037168522 GO:0019199 transmembrane receptor protein kinase activity 2/91 78/18639 0.0256410256410256 5.25190194420964 0.0557468521959867 0.336156037168522 GO:0008603 cAMP-dependent protein kinase regulator activity 1/91 12/18639 0.0833333333333333 17.0686813186813 0.0570553544516662 0.336156037168522 GO:0015132 prostaglandin transmembrane transporter activity 1/91 12/18639 0.0833333333333333 17.0686813186813 0.0570553544516662 0.336156037168522 GO:0016208 AMP binding 1/91 12/18639 0.0833333333333333 17.0686813186813 0.0570553544516662 0.336156037168522 GO:0097371 MDM2/MDM4 family protein binding 1/91 12/18639 0.0833333333333333 17.0686813186813 0.0570553544516662 0.336156037168522 GO:0033192 calmodulin-dependent protein phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0140791 histone H2AXS140 phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/91 81/18639 0.0246913580246914 5.05738705738706 0.0595901470256956 0.336156037168522 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/91 82/18639 0.024390243902439 4.9957116054677 0.0608911527847916 0.336156037168522 GO:0033549 MAP kinase phosphatase activity 2/91 82/18639 0.024390243902439 4.9957116054677 0.0608911527847916 0.336156037168522 GO:0071714 icosanoid transmembrane transporter activity 1/91 13/18639 0.0769230769230769 15.7557058326289 0.0616619987177793 0.336156037168522 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/91 83/18639 0.0240963855421687 4.93552230901629 0.0622019036427998 0.336156037168522 GO:0017018 myosin phosphatase activity 2/91 84/18639 0.0238095238095238 4.87676609105181 0.063522275855503 0.336156037168522 GO:0051117 ATPase binding 2/91 84/18639 0.0238095238095238 4.87676609105181 0.063522275855503 0.336156037168522 GO:0003779 actin binding 5/91 443/18639 0.0112866817155756 2.31178528018257 0.0657463382057989 0.336156037168522 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/91 14/18639 0.0714285714285714 14.6302982731554 0.0662463838845723 0.336156037168522 GO:0034236 protein kinase A catalytic subunit binding 1/91 14/18639 0.0714285714285714 14.6302982731554 0.0662463838845723 0.336156037168522 GO:0044548 S100 protein binding 1/91 14/18639 0.0714285714285714 14.6302982731554 0.0662463838845723 0.336156037168522 GO:0005041 low-density lipoprotein particle receptor activity 1/91 15/18639 0.0666666666666667 13.6549450549451 0.0708086163176731 0.336156037168522 GO:0033130 acetylcholine receptor binding 1/91 15/18639 0.0666666666666667 13.6549450549451 0.0708086163176731 0.336156037168522 GO:0050780 dopamine receptor binding 1/91 15/18639 0.0666666666666667 13.6549450549451 0.0708086163176731 0.336156037168522 GO:0120283 protein serine/threonine kinase binding 1/91 15/18639 0.0666666666666667 13.6549450549451 0.0708086163176731 0.336156037168522 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/91 16/18639 0.0625 12.801510989011 0.0753488018801245 0.336156037168522 GO:0003714 transcription corepressor activity 3/91 204/18639 0.0147058823529412 3.01212023270847 0.0780927527448499 0.336156037168522 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/91 17/18639 0.0588235294117647 12.0484809308339 0.0798670459347295 0.336156037168522 GO:0030169 low-density lipoprotein particle binding 1/91 17/18639 0.0588235294117647 12.0484809308339 0.0798670459347295 0.336156037168522 GO:0030548 acetylcholine receptor regulator activity 1/91 17/18639 0.0588235294117647 12.0484809308339 0.0798670459347295 0.336156037168522 GO:0038191 neuropilin binding 1/91 17/18639 0.0588235294117647 12.0484809308339 0.0798670459347295 0.336156037168522 GO:0022851 GABA-gated chloride ion channel activity 1/91 18/18639 0.0555555555555556 11.3791208791209 0.0843634533463896 0.336156037168522 GO:0030228 lipoprotein particle receptor activity 1/91 18/18639 0.0555555555555556 11.3791208791209 0.0843634533463896 0.336156037168522 GO:0034185 apolipoprotein binding 1/91 18/18639 0.0555555555555556 11.3791208791209 0.0843634533463896 0.336156037168522 GO:0070064 proline-rich region binding 1/91 18/18639 0.0555555555555556 11.3791208791209 0.0843634533463896 0.336156037168522 GO:0099602 neurotransmitter receptor regulator activity 1/91 18/18639 0.0555555555555556 11.3791208791209 0.0843634533463896 0.336156037168522 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/91 19/18639 0.0526315789473684 10.7802197802198 0.0888381284844316 0.336156037168522 GO:0004890 GABA-A receptor activity 1/91 19/18639 0.0526315789473684 10.7802197802198 0.0888381284844316 0.336156037168522 GO:0015245 fatty acid transmembrane transporter activity 1/91 19/18639 0.0526315789473684 10.7802197802198 0.0888381284844316 0.336156037168522 GO:0043395 heparan sulfate proteoglycan binding 1/91 19/18639 0.0526315789473684 10.7802197802198 0.0888381284844316 0.336156037168522 GO:0004722 protein serine/threonine phosphatase activity 2/91 103/18639 0.0194174757281553 3.97716846260536 0.0902796299757272 0.336156037168522 GO:0140297 DNA-binding transcription factor binding 5/91 488/18639 0.0102459016393443 2.09860835885426 0.0905234906203483 0.336156037168522 GO:0015095 magnesium ion transmembrane transporter activity 1/91 20/18639 0.05 10.2412087912088 0.093291175224921 0.336156037168522 GO:0016408 C-acyltransferase activity 1/91 20/18639 0.05 10.2412087912088 0.093291175224921 0.336156037168522 GO:0003712 transcription coregulator activity 5/91 495/18639 0.0101010101010101 2.06893106893107 0.0947626862287695 0.336156037168522 GO:0072542 protein phosphatase activator activity 1/91 21/18639 0.0476190476190476 9.75353218210361 0.09772269695297 0.336156037168522 GO:0005496 steroid binding 2/91 108/18639 0.0185185185185185 3.79304029304029 0.0977921013929886 0.336156037168522 GO:0004222 metalloendopeptidase activity 2/91 110/18639 0.0181818181818182 3.72407592407592 0.100845559201065 0.336156037168522 GO:0008093 cytoskeletal anchor activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0031683 G-protein beta/gamma-subunit complex binding 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0032931 histone H3K56 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0043992 histone H3K9 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0043993 histone H3K18 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0043994 histone H3K23 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0043999 histone H2AK5 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0044012 histone H2AK9 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0044014 histone H2BK5 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0044015 histone H2BK12 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0044016 histone H3K4 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0044017 histone H3K27 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0044018 histone H3K36 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0046972 histone H4K16 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0140908 histone H3K122 acetyltransferase activity 1/91 22/18639 0.0454545454545455 9.31018981018981 0.102132796565027 0.336156037168522 GO:0000287 magnesium ion binding 3/91 230/18639 0.0130434782608696 2.67161968466316 0.102671595024318 0.336156037168522 GO:0005158 insulin receptor binding 1/91 23/18639 0.0434782608695652 8.90539894887721 0.106521576471165 0.336156037168522 GO:0016917 GABA receptor activity 1/91 23/18639 0.0434782608695652 8.90539894887721 0.106521576471165 0.336156037168522 GO:0044013 histone H2B acetyltransferase activity 1/91 23/18639 0.0434782608695652 8.90539894887721 0.106521576471165 0.336156037168522 GO:0070577 lysine-acetylated histone binding 1/91 23/18639 0.0434782608695652 8.90539894887721 0.106521576471165 0.336156037168522 GO:0099186 structural constituent of postsynapse 1/91 23/18639 0.0434782608695652 8.90539894887721 0.106521576471165 0.336156037168522 GO:0001221 transcription coregulator binding 2/91 115/18639 0.0173913043478261 3.56215957955088 0.108593340944963 0.336156037168522 GO:0015149 hexose transmembrane transporter activity 1/91 24/18639 0.0416666666666667 8.53434065934066 0.110889138597354 0.336156037168522 GO:0043998 histone H2A acetyltransferase activity 1/91 24/18639 0.0416666666666667 8.53434065934066 0.110889138597354 0.336156037168522 GO:0050699 WW domain binding 1/91 24/18639 0.0416666666666667 8.53434065934066 0.110889138597354 0.336156037168522 GO:0055056 D-glucose transmembrane transporter activity 1/91 24/18639 0.0416666666666667 8.53434065934066 0.110889138597354 0.336156037168522 GO:0140033 acetylation-dependent protein binding 1/91 24/18639 0.0416666666666667 8.53434065934066 0.110889138597354 0.336156037168522 GO:0003707 nuclear steroid receptor activity 1/91 25/18639 0.04 8.19296703296703 0.115235584387719 0.336156037168522 GO:0004709 MAP kinase kinase kinase activity 1/91 25/18639 0.04 8.19296703296703 0.115235584387719 0.336156037168522 GO:0015645 fatty acid ligase activity 1/91 25/18639 0.04 8.19296703296703 0.115235584387719 0.336156037168522 GO:0019211 phosphatase activator activity 1/91 25/18639 0.04 8.19296703296703 0.115235584387719 0.336156037168522 GO:0120515 fatty acid-CoA ligase activity 1/91 25/18639 0.04 8.19296703296703 0.115235584387719 0.336156037168522 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/91 26/18639 0.0384615384615385 7.87785291631446 0.119561014806797 0.336156037168522 GO:0015145 monosaccharide transmembrane transporter activity 1/91 26/18639 0.0384615384615385 7.87785291631446 0.119561014806797 0.336156037168522 GO:0030507 spectrin binding 1/91 26/18639 0.0384615384615385 7.87785291631446 0.119561014806797 0.336156037168522 GO:0034237 protein kinase A regulatory subunit binding 1/91 26/18639 0.0384615384615385 7.87785291631446 0.119561014806797 0.336156037168522 GO:0050750 low-density lipoprotein particle receptor binding 1/91 26/18639 0.0384615384615385 7.87785291631446 0.119561014806797 0.336156037168522 GO:0005044 scavenger receptor activity 1/91 27/18639 0.037037037037037 7.58608058608058 0.123865530341776 0.336156037168522 GO:0008395 steroid hydroxylase activity 1/91 27/18639 0.037037037037037 7.58608058608058 0.123865530341776 0.336156037168522 GO:0016405 CoA-ligase activity 1/91 27/18639 0.037037037037037 7.58608058608058 0.123865530341776 0.336156037168522 GO:0035255 ionotropic glutamate receptor binding 1/91 27/18639 0.037037037037037 7.58608058608058 0.123865530341776 0.336156037168522 GO:0036408 histone H3K14 acetyltransferase activity 1/91 28/18639 0.0357142857142857 7.31514913657771 0.12814923100473 0.336156037168522 GO:0046875 ephrin receptor binding 1/91 28/18639 0.0357142857142857 7.31514913657771 0.12814923100473 0.336156037168522 GO:0046966 nuclear thyroid hormone receptor binding 1/91 28/18639 0.0357142857142857 7.31514913657771 0.12814923100473 0.336156037168522 GO:0051119 sugar transmembrane transporter activity 1/91 28/18639 0.0357142857142857 7.31514913657771 0.12814923100473 0.336156037168522 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/91 128/18639 0.015625 3.20037774725275 0.129426080182248 0.336156037168522 GO:0003785 actin monomer binding 1/91 29/18639 0.0344827586206897 7.06290261462675 0.132412216334835 0.336156037168522 GO:0010484 histone H3 acetyltransferase activity 1/91 29/18639 0.0344827586206897 7.06290261462675 0.132412216334835 0.336156037168522 GO:0043236 laminin binding 1/91 29/18639 0.0344827586206897 7.06290261462675 0.132412216334835 0.336156037168522 GO:0001968 fibronectin binding 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0031624 ubiquitin conjugating enzyme binding 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0043995 histone H4K5 acetyltransferase activity 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0043996 histone H4K8 acetyltransferase activity 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0043997 histone H4K12 acetyltransferase activity 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0051721 protein phosphatase 2A binding 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0098918 structural constituent of synapse 1/91 30/18639 0.0333333333333333 6.82747252747253 0.136654585400581 0.336156037168522 GO:0051087 protein-folding chaperone binding 2/91 134/18639 0.0149253731343284 3.0570772511071 0.13933524285636 0.336156037168522 GO:0005452 solute:inorganic anion antiporter activity 1/91 31/18639 0.032258064516129 6.60723147819922 0.140876436801975 0.336156037168522 GO:0016878 acid-thiol ligase activity 1/91 31/18639 0.032258064516129 6.60723147819922 0.140876436801975 0.336156037168522 GO:0070325 lipoprotein particle receptor binding 1/91 31/18639 0.032258064516129 6.60723147819922 0.140876436801975 0.336156037168522 GO:0140789 histone phosphatase activity 2/91 136/18639 0.0147058823529412 3.01212023270847 0.142674750118725 0.336156037168522 GO:0016922 nuclear receptor binding 2/91 137/18639 0.0145985401459854 2.9901339536376 0.144350968861345 0.336156037168522 GO:0008514 organic anion transmembrane transporter activity 3/91 269/18639 0.0111524163568773 2.28428448874546 0.144399721282221 0.336156037168522 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/91 32/18639 0.03125 6.40075549450549 0.145077868672731 0.336156037168522 GO:0042910 xenobiotic transmembrane transporter activity 1/91 32/18639 0.03125 6.40075549450549 0.145077868672731 0.336156037168522 GO:0071813 lipoprotein particle binding 1/91 32/18639 0.03125 6.40075549450549 0.145077868672731 0.336156037168522 GO:0071814 protein-lipid complex binding 1/91 32/18639 0.03125 6.40075549450549 0.145077868672731 0.336156037168522 GO:0016791 phosphatase activity 3/91 273/18639 0.010989010989011 2.25081511894699 0.148963080661562 0.339962389075349 GO:0030296 protein tyrosine kinase activator activity 1/91 33/18639 0.0303030303030303 6.20679320679321 0.149258978682446 0.339962389075349 GO:0004713 protein tyrosine kinase activity 2/91 140/18639 0.0142857142857143 2.92605965463108 0.149404523619956 0.339962389075349 GO:0019825 oxygen binding 1/91 34/18639 0.0294117647058824 6.02424046541694 0.153419864038777 0.344967741625653 GO:0090482 vitamin transmembrane transporter activity 1/91 34/18639 0.0294117647058824 6.02424046541694 0.153419864038777 0.344967741625653 GO:0019903 protein phosphatase binding 2/91 144/18639 0.0138888888888889 2.84478021978022 0.156197762253208 0.348099047477013 GO:0010485 histone H4 acetyltransferase activity 1/91 35/18639 0.0285714285714286 5.85211930926217 0.157560621489595 0.348099047477013 GO:0016229 steroid dehydrogenase activity 1/91 35/18639 0.0285714285714286 5.85211930926217 0.157560621489595 0.348099047477013 GO:0000993 RNA polymerase II complex binding 1/91 36/18639 0.0277777777777778 5.68956043956044 0.161681347325139 0.351079497048873 GO:0016409 palmitoyltransferase activity 1/91 36/18639 0.0277777777777778 5.68956043956044 0.161681347325139 0.351079497048873 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/91 36/18639 0.0277777777777778 5.68956043956044 0.161681347325139 0.351079497048873 GO:0043394 proteoglycan binding 1/91 37/18639 0.027027027027027 5.53578853578854 0.165782137380152 0.357938705707147 GO:0015144 carbohydrate transmembrane transporter activity 1/91 40/18639 0.025 5.1206043956044 0.17796584442173 0.379927083596952 GO:0071855 neuropeptide receptor binding 1/91 40/18639 0.025 5.1206043956044 0.17796584442173 0.379927083596952 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/91 41/18639 0.024390243902439 4.9957116054677 0.181987840666562 0.379974612380733 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/91 41/18639 0.024390243902439 4.9957116054677 0.181987840666562 0.379974612380733 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/91 41/18639 0.024390243902439 4.9957116054677 0.181987840666562 0.379974612380733 GO:0140318 protein transporter activity 1/91 41/18639 0.024390243902439 4.9957116054677 0.181987840666562 0.379974612380733 GO:0004402 histone acetyltransferase activity 1/91 42/18639 0.0238095238095238 4.87676609105181 0.185990373546405 0.382034280798022 GO:0042056 chemoattractant activity 1/91 42/18639 0.0238095238095238 4.87676609105181 0.185990373546405 0.382034280798022 GO:0043175 RNA polymerase core enzyme binding 1/91 42/18639 0.0238095238095238 4.87676609105181 0.185990373546405 0.382034280798022 GO:0008200 ion channel inhibitor activity 1/91 43/18639 0.0232558139534884 4.76335292614362 0.189973536207441 0.382324053504867 GO:0015103 inorganic anion transmembrane transporter activity 2/91 165/18639 0.0121212121212121 2.48271728271728 0.192715537261333 0.382324053504867 GO:0001223 transcription coactivator binding 1/91 44/18639 0.0227272727272727 4.6550949050949 0.19393742135506 0.382324053504867 GO:0016248 channel inhibitor activity 1/91 44/18639 0.0227272727272727 4.6550949050949 0.19393742135506 0.382324053504867 GO:0141110 transporter inhibitor activity 1/91 45/18639 0.0222222222222222 4.55164835164835 0.197882121255931 0.382324053504867 GO:0051020 GTPase binding 3/91 315/18639 0.00952380952380952 1.95070643642072 0.199413543520918 0.382324053504867 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/91 46/18639 0.0217391304347826 4.4526994744386 0.20180772774005 0.382324053504867 GO:0030291 protein serine/threonine kinase inhibitor activity 1/91 46/18639 0.0217391304347826 4.4526994744386 0.20180772774005 0.382324053504867 GO:0001784 phosphotyrosine residue binding 1/91 47/18639 0.0212765957446809 4.35796118774842 0.205714332202786 0.382324053504867 GO:0061733 protein-lysine-acetyltransferase activity 1/91 47/18639 0.0212765957446809 4.35796118774842 0.205714332202786 0.382324053504867 GO:0099095 ligand-gated monoatomic anion channel activity 1/91 47/18639 0.0212765957446809 4.35796118774842 0.205714332202786 0.382324053504867 GO:0032266 phosphatidylinositol-3-phosphate binding 1/91 48/18639 0.0208333333333333 4.26717032967033 0.209602025606914 0.382324053504867 GO:0038187 pattern recognition receptor activity 1/91 48/18639 0.0208333333333333 4.26717032967033 0.209602025606914 0.382324053504867 GO:0004721 phosphoprotein phosphatase activity 2/91 175/18639 0.0114285714285714 2.34084772370487 0.210485467733498 0.382324053504867 GO:0001222 transcription corepressor binding 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005004 GPI-linked ephrin receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005008 hepatocyte growth factor receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005009 insulin receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005011 macrophage colony-stimulating factor receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005020 stem cell factor receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0008288 boss receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0035254 glutamate receptor binding 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0036332 placental growth factor receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0038062 protein tyrosine kinase collagen receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0060175 brain-derived neurotrophic factor receptor activity 1/91 49/18639 0.0204081632653061 4.18008522090155 0.213470898484638 0.382324053504867 GO:0005319 lipid transporter activity 2/91 178/18639 0.0112359550561798 2.3013952339795 0.215850440703882 0.382324053504867 GO:0005006 epidermal growth factor receptor activity 1/91 50/18639 0.02 4.09648351648352 0.217321040939608 0.382324053504867 GO:0005007 fibroblast growth factor receptor activity 1/91 50/18639 0.02 4.09648351648352 0.217321040939608 0.382324053504867 GO:0005017 platelet-derived growth factor receptor activity 1/91 50/18639 0.02 4.09648351648352 0.217321040939608 0.382324053504867 GO:0005019 platelet-derived growth factor beta-receptor activity 1/91 50/18639 0.02 4.09648351648352 0.217321040939608 0.382324053504867 GO:0005021 vascular endothelial growth factor receptor activity 1/91 51/18639 0.0196078431372549 4.01616031027796 0.221152542648926 0.385495257828403 GO:0005030 neurotrophin receptor activity 1/91 51/18639 0.0196078431372549 4.01616031027796 0.221152542648926 0.385495257828403 GO:0008237 metallopeptidase activity 2/91 184/18639 0.0108695652173913 2.2263497372193 0.226617632997165 0.386350189150783 GO:0005003 ephrin receptor activity 1/91 53/18639 0.0188679245283019 3.86460709102219 0.228759980418227 0.386350189150783 GO:0005005 transmembrane-ephrin receptor activity 1/91 53/18639 0.0188679245283019 3.86460709102219 0.228759980418227 0.386350189150783 GO:0017046 peptide hormone binding 1/91 53/18639 0.0188679245283019 3.86460709102219 0.228759980418227 0.386350189150783 GO:0034212 protein N-acetyltransferase activity 1/91 53/18639 0.0188679245283019 3.86460709102219 0.228759980418227 0.386350189150783 GO:0038064 collagen receptor activity 1/91 53/18639 0.0188679245283019 3.86460709102219 0.228759980418227 0.386350189150783 GO:0051018 protein kinase A binding 1/91 53/18639 0.0188679245283019 3.86460709102219 0.228759980418227 0.386350189150783 GO:0003925 G protein activity 1/91 54/18639 0.0185185185185185 3.79304029304029 0.232536093717589 0.3892674696594 GO:0050661 NADP binding 1/91 54/18639 0.0185185185185185 3.79304029304029 0.232536093717589 0.3892674696594 GO:0046943 carboxylic acid transmembrane transporter activity 2/91 188/18639 0.0106382978723404 2.17898059387421 0.23381862402689 0.389697706711484 GO:0005342 organic acid transmembrane transporter activity 2/91 189/18639 0.0105820105820106 2.16745159602302 0.235621245287656 0.390987219254625 GO:0019902 phosphatase binding 2/91 190/18639 0.0105263157894737 2.15604395604396 0.23742471313495 0.392266917353396 GO:0030170 pyridoxal phosphate binding 1/91 56/18639 0.0178571428571429 3.65757456828885 0.240033549101578 0.394860383803461 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/91 349/18639 0.00859598853868195 1.76066626782959 0.24284893968207 0.39584156004059 GO:0016504 peptidase activator activity 1/91 57/18639 0.0175438596491228 3.59340659340659 0.243755065919732 0.39584156004059 GO:0070279 vitamin B6 binding 1/91 57/18639 0.0175438596491228 3.59340659340659 0.243755065919732 0.39584156004059 GO:0141003 histone H2AX kinase activity 3/91 354/18639 0.00847457627118644 1.73579810020488 0.249373865332708 0.398471147294227 GO:0004879 nuclear receptor activity 1/91 59/18639 0.0169491525423729 3.47159620040976 0.251144111543507 0.398471147294227 GO:0015459 potassium channel regulator activity 1/91 59/18639 0.0169491525423729 3.47159620040976 0.251144111543507 0.398471147294227 GO:0045309 protein phosphorylated amino acid binding 1/91 59/18639 0.0169491525423729 3.47159620040976 0.251144111543507 0.398471147294227 GO:0070063 RNA polymerase binding 1/91 59/18639 0.0169491525423729 3.47159620040976 0.251144111543507 0.398471147294227 GO:0140996 histone H3 kinase activity 3/91 357/18639 0.00840336134453781 1.7212115615477 0.253302190458656 0.398471147294227 GO:0001098 basal transcription machinery binding 1/91 60/18639 0.0166666666666667 3.41373626373626 0.254811812611835 0.398471147294227 GO:0001099 basal RNA polymerase II transcription machinery binding 1/91 60/18639 0.0166666666666667 3.41373626373626 0.254811812611835 0.398471147294227 GO:0098531 ligand-modulated transcription factor activity 1/91 60/18639 0.0166666666666667 3.41373626373626 0.254811812611835 0.398471147294227 GO:0035173 histone kinase activity 3/91 360/18639 0.00833333333333333 1.70686813186813 0.257239871522916 0.400619472043886 GO:0042578 phosphoric ester hydrolase activity 3/91 363/18639 0.00826446280991736 1.69276178367087 0.261186365528248 0.404860648649849 GO:0015179 L-amino acid transmembrane transporter activity 1/91 62/18639 0.0161290322580645 3.30361573909961 0.262093998862797 0.404860648649849 GO:0022824 transmitter-gated monoatomic ion channel activity 1/91 63/18639 0.0158730158730159 3.25117739403454 0.265708653871866 0.405499150487186 GO:0022835 transmitter-gated channel activity 1/91 63/18639 0.0158730158730159 3.25117739403454 0.265708653871866 0.405499150487186 GO:1901682 sulfur compound transmembrane transporter activity 1/91 63/18639 0.0158730158730159 3.25117739403454 0.265708653871866 0.405499150487186 GO:0046982 protein heterodimerization activity 3/91 369/18639 0.00813008130081301 1.66523720182257 0.269103647878192 0.409037544774852 GO:0051015 actin filament binding 2/91 209/18639 0.00956937799043062 1.96003996003996 0.271786879175605 0.411470175644342 GO:0050840 extracellular matrix binding 1/91 67/18639 0.0149253731343284 3.0570772511071 0.279992982397013 0.422104019065049 GO:0005525 GTP binding 3/91 378/18639 0.00793650793650794 1.62558869701727 0.281032412693309 0.422104019065049 GO:1990841 promoter-specific chromatin binding 1/91 68/18639 0.0147058823529412 3.01212023270847 0.283520908231703 0.424165138299398 GO:0002039 p53 binding 1/91 69/18639 0.0144927536231884 2.9684663162924 0.287031736800489 0.426062734313225 GO:0008080 N-acetyltransferase activity 1/91 69/18639 0.0144927536231884 2.9684663162924 0.287031736800489 0.426062734313225 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/91 70/18639 0.0142857142857143 2.92605965463108 0.290525550045031 0.429570852206661 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/91 73/18639 0.0136986301369863 2.80581062772844 0.300905711435808 0.439679007703268 GO:0003684 damaged DNA binding 1/91 74/18639 0.0135135135135135 2.76789426789427 0.304332275060679 0.439679007703268 GO:0048029 monosaccharide binding 1/91 74/18639 0.0135135135135135 2.76789426789427 0.304332275060679 0.439679007703268 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/91 229/18639 0.00873362445414847 1.78885743077883 0.307925599681512 0.439679007703268 GO:0019001 guanyl nucleotide binding 3/91 400/18639 0.0075 1.53618131868132 0.310379578892496 0.439679007703268 GO:0032561 guanyl ribonucleotide binding 3/91 400/18639 0.0075 1.53618131868132 0.310379578892496 0.439679007703268 GO:0098631 cell adhesion mediator activity 1/91 76/18639 0.0131578947368421 2.69505494505495 0.311135647735463 0.439679007703268 GO:0048306 calcium-dependent protein binding 1/91 80/18639 0.0125 2.5603021978022 0.32454559149541 0.439679007703268 GO:0001618 virus receptor activity 1/91 81/18639 0.0123456790123457 2.52869352869353 0.327857534551281 0.439679007703268 GO:0015101 organic cation transmembrane transporter activity 1/91 81/18639 0.0123456790123457 2.52869352869353 0.327857534551281 0.439679007703268 GO:0140272 exogenous protein binding 1/91 82/18639 0.0121951219512195 2.49785580273385 0.331153415807657 0.439679007703268 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/91 243/18639 0.00823045267489712 1.68579568579569 0.333040078706329 0.439679007703268 GO:0005254 chloride channel activity 1/91 83/18639 0.0120481927710843 2.46776115450814 0.334433312297473 0.439679007703268 GO:0030165 PDZ domain binding 1/91 83/18639 0.0120481927710843 2.46776115450814 0.334433312297473 0.439679007703268 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0004711 ribosomal protein S6 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0035175 histone H3S10 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0035979 histone H2AXS139 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0044022 histone H3S28 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0044023 histone H4S1 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0044024 histone H2AS1 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0044025 histone H2BS14 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0072354 histone H3T3 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0072371 histone H2AS121 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0140823 histone H2BS36 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0140855 histone H3S57 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0140995 histone H2A kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0140997 histone H4 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0140998 histone H2B kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:1990244 histone H2AT120 kinase activity 2/91 245/18639 0.00816326530612245 1.67203408836062 0.336609103641159 0.439679007703268 GO:0004860 protein kinase inhibitor activity 1/91 84/18639 0.0119047619047619 2.4383830455259 0.33769730068834 0.439679007703268 GO:0004677 DNA-dependent protein kinase activity 2/91 246/18639 0.00813008130081301 1.66523720182257 0.338391597223447 0.439679007703268 GO:0140857 histone H3T45 kinase activity 2/91 246/18639 0.00813008130081301 1.66523720182257 0.338391597223447 0.439679007703268 GO:0035402 histone H3T11 kinase activity 2/91 247/18639 0.00809716599190283 1.65849535080304 0.340172705959897 0.439679007703268 GO:0035403 histone H3T6 kinase activity 2/91 247/18639 0.00809716599190283 1.65849535080304 0.340172705959897 0.439679007703268 GO:0042393 histone binding 2/91 247/18639 0.00809716599190283 1.65849535080304 0.340172705959897 0.439679007703268 GO:0004679 AMP-activated protein kinase activity 2/91 248/18639 0.00806451612903226 1.65180786954981 0.341952401046748 0.440481058975472 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/91 86/18639 0.0116279069767442 2.38167646307181 0.344177858027345 0.441849952872942 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/91 89/18639 0.0112359550561798 2.3013952339795 0.353781279167585 0.44911176615076 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/91 89/18639 0.0112359550561798 2.3013952339795 0.353781279167585 0.44911176615076 GO:0019887 protein kinase regulator activity 2/91 255/18639 0.00784313725490196 1.60646412411118 0.354368329004039 0.44911176615076 GO:0004674 protein serine/threonine kinase activity 3/91 433/18639 0.0069284064665127 1.41910514427835 0.354561920645337 0.44911176615076 GO:0019210 kinase inhibitor activity 1/91 90/18639 0.0111111111111111 2.27582417582418 0.35695140874148 0.449144156694578 GO:0140793 histone H2AXY142 phosphatase activity 1/91 90/18639 0.0111111111111111 2.27582417582418 0.35695140874148 0.449144156694578 GO:0051219 phosphoprotein binding 1/91 93/18639 0.010752688172043 2.20241049273307 0.366369803266598 0.45947368066438 GO:0016410 N-acyltransferase activity 1/91 94/18639 0.0106382978723404 2.17898059387421 0.369478848230619 0.461848560288274 GO:0004896 cytokine receptor activity 1/91 96/18639 0.0104166666666667 2.13358516483516 0.375651745427367 0.466495631576469 GO:0016407 acetyltransferase activity 1/91 96/18639 0.0104166666666667 2.13358516483516 0.375651745427367 0.466495631576469 GO:0030594 neurotransmitter receptor activity 1/91 97/18639 0.0103092783505155 2.11158944148635 0.378715742146674 0.468768671061029 GO:0004725 protein tyrosine phosphatase activity 1/91 98/18639 0.0102040816326531 2.09004261045077 0.381764866699832 0.470306479883327 GO:0005096 GTPase activator activity 2/91 271/18639 0.00738007380073801 1.51161753375775 0.382433427063021 0.470306479883327 GO:0015171 amino acid transmembrane transporter activity 1/91 102/18639 0.00980392156862745 2.00808015513898 0.393814065957082 0.4827398227861 GO:0005253 monoatomic anion channel activity 1/91 103/18639 0.00970873786407767 1.98858423130268 0.396789893760821 0.484742708311374 GO:0030246 carbohydrate binding 2/91 280/18639 0.00714285714285714 1.46302982731554 0.39799927629776 0.484742708311374 GO:0031267 small GTPase binding 2/91 283/18639 0.00706713780918728 1.44752067720266 0.403148942994191 0.48944600107921 GO:0004497 monooxygenase activity 1/91 106/18639 0.00943396226415094 1.93230354551109 0.405630961060682 0.490890971984264 GO:0019888 protein phosphatase regulator activity 1/91 107/18639 0.00934579439252336 1.9142446338708 0.408549408292294 0.492853254447847 GO:0019207 kinase regulator activity 2/91 287/18639 0.00696864111498258 1.42734617299077 0.409983408082865 0.493018022378129 GO:1902936 phosphatidylinositol bisphosphate binding 1/91 111/18639 0.00900900900900901 1.84526284526285 0.420082142962017 0.503568499449736 GO:0005200 structural constituent of cytoskeleton 1/91 112/18639 0.00892857142857143 1.82878728414443 0.422930401003384 0.5053885295009 GO:0030695 GTPase regulator activity 3/91 489/18639 0.00613496932515337 1.25659003573114 0.428577335875569 0.509096648861261 GO:0060589 nucleoside-triphosphatase regulator activity 3/91 490/18639 0.00612244897959184 1.25402556627046 0.429876826639324 0.509096648861261 GO:0035401 histone H3Y41 kinase activity 1/91 115/18639 0.00869565217391304 1.78107978977544 0.431392423508753 0.509096648861261 GO:0140801 histone H2AXY142 kinase activity 1/91 115/18639 0.00869565217391304 1.78107978977544 0.431392423508753 0.509096648861261 GO:0009055 electron transfer activity 1/91 116/18639 0.00862068965517241 1.76572565365669 0.434185734319631 0.510502806717089 GO:0031625 ubiquitin protein ligase binding 2/91 302/18639 0.00662251655629139 1.35645149552434 0.435270814148255 0.510502806717089 GO:0019208 phosphatase regulator activity 1/91 117/18639 0.00854700854700855 1.75063398140321 0.436965472924442 0.510913476034732 GO:0015108 chloride transmembrane transporter activity 1/91 121/18639 0.00826446280991736 1.69276178367087 0.447950004959022 0.522150312528921 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/91 122/18639 0.00819672131147541 1.67888668708341 0.450662854594443 0.523706069559292 GO:0044389 ubiquitin-like protein ligase binding 2/91 322/18639 0.0062111801242236 1.2721998498396 0.468077040893327 0.542284376644709 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/91 132/18639 0.00757575757575758 1.5516983016983 0.477076505435135 0.551030614180399 GO:0015297 antiporter activity 1/91 135/18639 0.00740740740740741 1.51721611721612 0.484752787560391 0.558200179614996 GO:0044325 transmembrane transporter binding 1/91 136/18639 0.00735294117647059 1.50606011635423 0.487286698948848 0.559422796376321 GO:0030295 protein kinase activator activity 1/91 139/18639 0.00719424460431655 1.47355522175666 0.494814719155324 0.56465343327034 GO:0140767 enzyme-substrate adaptor activity 1/91 139/18639 0.00719424460431655 1.47355522175666 0.494814719155324 0.56465343327034 GO:0020037 heme binding 1/91 142/18639 0.00704225352112676 1.44242377340969 0.502233404605668 0.571403274701059 GO:0019955 cytokine binding 1/91 144/18639 0.00694444444444444 1.42239010989011 0.507119229879409 0.5752397234453 GO:0061630 ubiquitin protein ligase activity 2/91 353/18639 0.0056657223796034 1.16047691685085 0.516658757625095 0.582684367469434 GO:0019209 kinase activator activity 1/91 148/18639 0.00675675675675676 1.38394713394713 0.516749031150524 0.582684367469434 GO:0008509 monoatomic anion transmembrane transporter activity 1/91 149/18639 0.00671140939597315 1.37465889814883 0.519127260460205 0.583634198150526 GO:0019842 vitamin binding 1/91 150/18639 0.00666666666666667 1.36549450549451 0.521493913748367 0.584565449039468 GO:0046906 tetrapyrrole binding 1/91 152/18639 0.00657894736842105 1.34752747252747 0.526192714887632 0.58809774016853 GO:0106310 protein serine kinase activity 2/91 361/18639 0.00554016620498615 1.13475997686524 0.528720639099177 0.58919015500788 GO:0005506 iron ion binding 1/91 154/18639 0.00649350649350649 1.3300271157414 0.530845877178456 0.589828752420507 GO:0140375 immune receptor activity 1/91 156/18639 0.00641025641025641 1.31297548605241 0.53545383902704 0.593214165685934 GO:0099106 ion channel regulator activity 1/91 160/18639 0.00625 1.2801510989011 0.544535894239126 0.600263457375494 GO:0061659 ubiquitin-like protein ligase activity 2/91 372/18639 0.00537634408602151 1.10120524636654 0.544976033669857 0.600263457375494 GO:0016874 ligase activity 1/91 167/18639 0.00598802395209581 1.22649207080345 0.560008870430439 0.615038643825337 GO:0016247 channel regulator activity 1/91 168/18639 0.00595238095238095 1.21919152276295 0.562176431755191 0.615639896446607 GO:0141108 transporter regulator activity 1/91 170/18639 0.00588235294117647 1.20484809308339 0.566479920950208 0.61857002862379 GO:0008201 heparin binding 1/91 172/18639 0.00581395348837209 1.19083823153591 0.570741570272346 0.621437812903987 GO:0140030 modification-dependent protein binding 1/91 173/18639 0.00578034682080925 1.18395477355015 0.572856830850957 0.621958844923896 GO:0016853 isomerase activity 1/91 180/18639 0.00555555555555556 1.13791208791209 0.587377757750667 0.635907544003572 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/91 181/18639 0.00552486187845304 1.13162528079655 0.589411921250569 0.636296960440955 GO:0004175 endopeptidase activity 2/91 405/18639 0.00493827160493827 1.01147741147741 0.591402555236762 0.636637311586316 GO:1901981 phosphatidylinositol phosphate binding 1/91 185/18639 0.00540540540540541 1.10715770715771 0.597449867899482 0.64133036667176 GO:0015276 ligand-gated monoatomic ion channel activity 1/91 186/18639 0.00537634408602151 1.10120524636654 0.599434915153256 0.6416486415725 GO:0031406 carboxylic acid binding 1/91 187/18639 0.0053475935828877 1.09531644825762 0.601410280823936 0.641954794137909 GO:0022834 ligand-gated channel activity 1/91 188/18639 0.00531914893617021 1.08949029693711 0.603376011608947 0.642248975942296 GO:0043177 organic acid binding 1/91 189/18639 0.00529100529100529 1.08372579801151 0.605332153982996 0.642531336629996 GO:0005516 calmodulin binding 1/91 207/18639 0.00483091787439614 0.989488772097468 0.638954773934316 0.676330958482005 GO:0004842 ubiquitin-protein transferase activity 2/91 449/18639 0.0044543429844098 0.912357130619937 0.647769599757416 0.683756799743939 GO:0005085 guanyl-nucleotide exchange factor activity 1/91 230/18639 0.00434782608695652 0.890539894887721 0.677822923863921 0.713497814593601 GO:0019787 ubiquitin-like protein transferase activity 2/91 479/18639 0.00417536534446764 0.85521576544541 0.682606681380038 0.716186672501139 GO:0005125 cytokine activity 1/91 234/18639 0.00427350427350427 0.875316990701606 0.684146742415561 0.716186672501139 GO:0005539 glycosaminoglycan binding 1/91 242/18639 0.00413223140495868 0.846380891835437 0.696428371012651 0.727040607101119 GO:0016755 aminoacyltransferase activity 2/91 496/18639 0.00403225806451613 0.825903934774903 0.701086300790841 0.729898066576766 GO:0033218 amide binding 1/91 247/18639 0.00404858299595142 0.829247675401522 0.703863284153069 0.730787016333788 GO:0003730 mRNA 3'-UTR binding 1/91 262/18639 0.00381679389312977 0.781771663451053 0.725104353429124 0.750789248782199 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/91 268/18639 0.00373134328358209 0.764269312776776 0.733172431743027 0.757080228430299 GO:1901681 sulfur compound binding 1/91 275/18639 0.00363636363636364 0.744815184815185 0.742289575727312 0.763663015559344 GO:0008017 microtubule binding 1/91 276/18639 0.0036231884057971 0.742116579073101 0.743566620413045 0.763663015559344 GO:0001217 DNA-binding transcription repressor activity 1/91 278/18639 0.00359712230215827 0.73677761087833 0.746101963120907 0.764201471660229 GO:0035091 phosphatidylinositol binding 1/91 284/18639 0.00352112676056338 0.721211886704844 0.753560183977797 0.769765779332158 GO:0015291 secondary active transmembrane transporter activity 1/91 287/18639 0.00348432055749129 0.713673086495386 0.757207620685668 0.771417951368778 GO:0022836 gated channel activity 1/91 318/18639 0.00314465408805031 0.644101181837031 0.791907711256199 0.804612113041058 GO:0015631 tubulin binding 1/91 385/18639 0.0025974025974026 0.532010846296561 0.851027598160295 0.862374632802433 GO:0016887 ATP hydrolysis activity 1/91 417/18639 0.00239808153477218 0.491185073918887 0.873061955460916 0.882349848604117 GO:0005216 monoatomic ion channel activity 1/91 448/18639 0.00223214285714286 0.457196821036107 0.891324086046018 0.897130432127082 GO:0046873 metal ion transmembrane transporter activity 1/91 450/18639 0.00222222222222222 0.455164835164835 0.892408693010624 0.897130432127082 GO:0022804 active transmembrane transporter activity 1/91 457/18639 0.00218818380743982 0.448192944910669 0.89612118472751 0.898485620571118 GO:0005543 phospholipid binding 1/91 497/18639 0.00201207243460765 0.412121078117054 0.915029153824965 0.915029153824965