category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/10	217/9376	12.9622119815668	MGST1/FOS/GNAI1	5.82540190027202
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	2/10	59/9376	31.7830508474576	MGST1/GPX3	7.75011557860346
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/10	78/9376	24.0410256410256	FOS/GNAI1	6.67671593237545
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/10	95/9376	19.7389473684211	FOS/IL18	5.99816169713102
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/10	97/9376	19.3319587628866	FOS/GNAI1	5.92997295803835
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/10	103/9376	18.2058252427184	FOS/GNAI1	5.73710173812424
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/10	115/9376	16.3060869565217	FOS/GNAI1	5.39625812853931
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/10	115/9376	16.3060869565217	FOS/GNAI1	5.39625812853931
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/10	116/9376	16.1655172413793	DLGAP1/GNAI1	5.37018552806487
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/10	122/9376	15.3704918032787	FOS/GNAI1	5.22029878357436
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/10	130/9376	14.4246153846154	FOS/GNAI1	5.03622523817308
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/10	133/9376	14.0992481203008	FOS/GNAI1	4.97134924278188
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/10	138/9376	13.5884057971014	FOS/IL18	4.86776787255026
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/10	139/9376	13.4906474820144	FOS/GNAI1	4.84769671557028
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/10	142/9376	13.2056338028169	MGST1/FOS	4.78870555842025
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/10	154/9376	12.1766233766234	FOS/GNAI1	4.56948209074243
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/10	200/9376	9.376	FOS/IL18	3.91231239470796
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/10	201/9376	9.32935323383085	DDX5/ELK4	3.90045106749451
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/10	214/9376	8.76261682242991	FOS/GNAI1	3.75343114656263
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/10	216/9376	8.68148148148148	FOS/IL18	3.73192311733216
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/10	224/9376	8.37142857142857	FOS/ELK4	3.64859977095016
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/10	226/9376	8.29734513274336	FOS/GNAI1	3.62841639803844
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/10	227/9376	8.26079295154185	MGST1/FOS	3.61841794771342
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/10	248/9376	7.56129032258064	FOS/IL18	3.4216520277221
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/10	300/9376	6.25066666666667	FOS/ELK4	3.02020480131235
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/10	37/9376	25.3405405405405	IL18	4.84718342447751
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/10	49/9376	19.134693877551	GNAI1	4.15858748245731
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/10	50/9376	18.752	IL18	4.11237913792335
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/10	56/9376	16.7428571428571	SMURF1	3.86080772294824
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/10	56/9376	16.7428571428571	IL18	3.86080772294824
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/10	59/9376	15.8915254237288	GNAI1	3.74917495174595
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/10	60/9376	15.6266666666667	GNAI1	3.71376835190402
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/10	66/9376	14.2060606060606	IL18	3.517863425627
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/10	69/9376	13.5884057971014	GNAI1	3.42924871189659
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/10	69/9376	13.5884057971014	FOS	3.42924871189659
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/10	70/9376	13.3942857142857	MGST1	3.40092896318855
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/10	71/9376	13.2056338028169	FOS	3.37318284588198
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/10	73/9376	12.8438356164384	MGST1	3.31933321804545
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/10	75/9376	12.5013333333333	MGST1	3.26755240410392
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/10	75/9376	12.5013333333333	GPX3	3.26755240410392
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/10	76/9376	12.3368421052632	GNAI1	3.24239545040033
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/10	78/9376	12.0205128205128	DCPS	3.19347040700531
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/10	78/9376	12.0205128205128	FOS	3.19347040700531
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/10	79/9376	11.8683544303797	MGST1	3.16967317553443
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/10	82/9376	11.4341463414634	MGST1	3.10078087768564
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/10	83/9376	11.2963855421687	IL18	3.07860829494085
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/10	87/9376	10.7770114942529	FOS	2.99357285507245
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/10	89/9376	10.5348314606742	GNAI1	2.95310482242529
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/10	89/9376	10.5348314606742	GNAI1	2.95310482242529
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/10	90/9376	10.4177777777778	FOS	2.93335020347351
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/10	91/9376	10.3032967032967	FOS	2.91390356919553
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/10	91/9376	10.3032967032967	GNAI1	2.91390356919553
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/10	93/9376	10.0817204301075	SMURF1	2.87590137907532
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/10	93/9376	10.0817204301075	FOS	2.87590137907532
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/10	94/9376	9.97446808510638	FOS	2.85733014932406
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/10	99/9376	9.47070707070707	FOS	2.76848416590419
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/10	99/9376	9.47070707070707	FOS	2.76848416590419
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/10	100/9376	9.376	IL18	2.75147049555261
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/10	101/9376	9.28316831683168	GNAI1	2.73469423867817
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/10	105/9376	8.92952380952381	SMURF1	2.66985101952106
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/10	109/9376	8.60183486238532	FOS	2.60837878921144
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/10	109/9376	8.60183486238532	FOS	2.60837878921144
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/10	110/9376	8.52363636363636	SMURF1	2.59350179527877
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/10	110/9376	8.52363636363636	GNAI1	2.59350179527877
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/10	112/9376	8.37142857142857	GNAI1	2.56430666545481
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/10	115/9376	8.15304347826087	GNAI1	2.52185088997639
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/10	116/9376	8.08275862068966	GNAI1	2.50804026253871
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/10	119/9376	7.87899159663865	FOS	2.46758254342078
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/10	122/9376	7.68524590163935	FOS	2.42851681946341
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/10	125/9376	7.5008	GNAI1	2.39076028338829
Organismal Systems	Immune system	hsa04611	Platelet activation	1/10	126/9376	7.44126984126984	GNAI1	2.37845238142504
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/10	136/9376	6.89411764705882	FOS	2.26235539828512
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/10	137/9376	6.84379562043796	FOS	2.25139335593716
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/10	140/9376	6.69714285714286	GNAI1	2.21915545793386
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/10	142/9376	6.60281690140845	SMURF1	2.19818494246432
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/10	142/9376	6.60281690140845	FOS	2.19818494246432
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/10	148/9376	6.33513513513514	FOS	2.1376226891942
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/10	149/9376	6.29261744966443	GNAI1	2.12785455669556
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/10	154/9376	6.08831168831169	GNAI1	2.08031964112582
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/10	155/9376	6.04903225806452	GNAI1	2.07106412055727
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/10	157/9376	5.97197452229299	FOS	2.05279402397619
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/10	163/9376	5.7521472392638	FOS	1.99982372498357
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/10	166/9376	5.64819277108434	GNAI1	1.97431716488593
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/10	170/9376	5.51529411764706	MGST1	1.94125944417248
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/10	173/9376	5.41965317919075	IL18	1.9171455797759
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/10	181/9376	5.18011049723757	IL18	1.85549481123672
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/10	184/9376	5.09565217391304	GNAI1	1.83330841514334
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/10	187/9376	5.01390374331551	IL18	1.81159950157066
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/10	191/9376	4.90890052356021	GNAI1	1.78336518116429
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/10	193/9376	4.8580310880829	GNAI1	1.76954106954638
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/10	196/9376	4.78367346938775	FOS	1.74915745877875
NA	NA	hsa04082	Neuroactive ligand signaling	1/10	199/9376	4.71155778894472	GNAI1	1.72918301394425
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/10	204/9376	4.59607843137255	DDX5	1.69676140639628
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/10	212/9376	4.42264150943396	GNAI1	1.64700669593709
NA	NA	hsa04081	Hormone signaling	1/10	219/9376	4.28127853881278	GNAI1	1.60545120271614
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/10	227/9376	4.13039647577093	GNAI1	1.56003385125904
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/10	238/9376	3.93949579831933	FOS	1.50087425094791
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/10	243/9376	3.85843621399177	DDX5	1.47514079922604
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/10	250/9376	3.7504	SMURF1	1.44023775972463
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/10	253/9376	3.70592885375494	IL18	1.42566129195269
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/10	268/9376	3.49850746268657	GNAI1	1.35595444303587
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/10	298/9376	3.14630872483221	IL18	1.23030785076557
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	1/10	308/9376	3.04415584415584	GPX3	1.19190644145115
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/10	368/9376	2.54782608695652	GPX3	0.989784033994081
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/10	480/9376	1.95333333333333	GPX3	0.700610386565012