category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 13/88 205/9376 6.75654101995565 SLC2A1/MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/CD36/MT-CO2/GAPDH 8.11140448235451 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 10/88 138/9376 7.72068511198946 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2 7.74158671539153 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 11/88 227/9376 5.16299559471366 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2/FOS 6.18013464459044 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 8/88 110/9376 7.74876033057851 ID3/SMAD6/SMAD9/ID1/LTBP1/THBS1/BMP6/ID2 6.9301090857417 Human Diseases Neurodegenerative disease hsa05020 Prion disease 12/88 275/9376 4.64925619834711 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/HSPA6/MT-CO2/HSPA8 5.97849699096231 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 11/88 235/9376 4.98723404255319 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2/ACTB 6.02524451712844 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 7/88 89/9376 8.37997957099081 COL4A2/COL4A1/LAMA2/THBS1/CD36/FN1/COL6A1 6.80892124685945 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 11/88 268/9376 4.37313432835821 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2/GNAI2 5.45324981621642 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 7/88 116/9376 6.4294670846395 EZR/PECAM1/MYL12B/JAM3/ACTB/JAM2/GNAI2 5.72725574849428 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 9/88 203/9376 4.72369010300045 COL4A2/COL4A1/LAMA2/MYL12B/THBS1/FN1/ACTB/EMP1/COL6A1 5.22073589244437 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 5/88 52/9376 10.2447552447552 HSD17B2/SCARB1/CYP19A1/CGA/BMP6 6.50671564915042 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 12/88 362/9376 3.5318935208438 CSH1/COL4A2/CSH2/CSHL1/COL4A1/LAMA2/GNGT1/HSP90AB1/THBS1/FN1/HSP90B1/COL6A1 4.7819696642332 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 12/88 388/9376 3.29522024367385 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2/LRP6/GAPDH 4.49442944925313 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 9/88 233/9376 4.11548966055404 COL4A2/COL4A1/LAMA2/SPTAN1/THBS1/FN1/ACTB/COL6A1/VIM 4.68733276075856 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 7/88 149/9376 5.00549115314216 MT-ND4/GNGT1/MT-ND3/MT-ND2/MT-ND1/MT-ND5/GNAI2 4.79716351153526 NA NA hsa04518 Integrin signaling 7/88 154/9376 4.84297520661157 COL4A2/COL4A1/LAMA2/THBS1/FN1/ACTB/COL6A1 4.6803815097465 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 10/88 308/9376 3.45926800472255 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2 4.2716074280467 Cellular Processes Transport and catabolism hsa04145 Phagosome 7/88 155/9376 4.81173020527859 FCGR2B/SCARB1/FCGR2A/THBS1/CD36/ACTB/CALR 4.65762868311266 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 11/88 368/9376 3.18478260869565 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2/ACTB 4.16182506608818 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 7/88 157/9376 4.7504342790967 SLC2A1/PECAM1/BSG/THBS1/CD36/MERTK/CALR 4.61270147800354 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 7/88 170/9376 4.38716577540107 EZR/MYL12B/JAM3/MYL6/ACTB/JAM2/CTTN 4.33801749150783 Human Diseases Infectious disease: parasitic hsa05144 Malaria 4/88 50/9376 8.52363636363636 PECAM1/THBS1/CD36/CD81 5.19195553422367 NA NA hsa04517 IgSF CAM signaling 9/88 299/9376 3.20705381574947 EZR/SPTAN1/MYL12B/EPB41L3/JAM3/MYL6/SORBS1/ACTB/JAM2 3.77522830303463 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 6/88 139/9376 4.59908436886854 HSP90AB1/HSPA6/HSPA8/HSP90B1/FOS/GNAI2 4.16102022404239 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 5/88 103/9376 5.1721094439541 COL4A2/COL4A1/COL15A1/COL18A1/COL6A1 4.14409827402134 NA NA hsa04081 Hormone signaling 7/88 219/9376 3.40556247405562 CSH1/CSH2/CSHL1/SMAD9/GNGT1/CGA/GNAI2 3.50612957007362 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 11/88 480/9376 2.44166666666667 MT-ND4/MT-CYB/MT-CO3/MT-ATP6/MT-ND3/MT-ND2/MT-ND1/MT-ND5/MT-CO1/MT-CO2/LRP6 3.15612328652185 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 5/88 122/9376 4.36661698956781 CSH1/CSH2/CSHL1/FOS/GNAI2 3.64313067701815 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 6/88 174/9376 3.67398119122257 HSP90AB1/HSPA6/HSPA8/TUSC3/HSP90B1/CALR 3.46543477141353 Organismal Systems Immune system hsa04612 Antigen processing and presentation 4/88 82/9376 5.19733924611973 HSP90AB1/HSPA6/HSPA8/CALR 3.71574186043183 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 5/88 130/9376 4.0979020979021 COL4A2/COL4A1/GNGT1/FOS/GNAI2 3.46200978693018 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 7/88 248/9376 3.00733137829912 HSP90AB1/MYL12B/ACTB/HSP90B1/GAPDH/FOS/RHOB 3.11833643504164 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 4/88 87/9376 4.89864158829676 MT-CYB/MT-CO3/MT-CO1/MT-CO2 3.55593920259071 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 5/88 142/9376 3.75160051216389 PECAM1/HSP90AB1/ACTB/HSP90B1/FOS 3.21588484907414 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 6/88 200/9376 3.19636363636364 FCGR2A/EZR/ACTB/GAPDH/FOS/CTTN 3.05603561422927 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 4/88 93/9376 4.58260019550342 COL4A2/COL4A1/LAMA2/FN1 3.37957053650114 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 6/88 216/9376 2.95959595959596 HSP90AB1/HSPA6/CD36/HSPA8/HSP90B1/FOS 2.83603473053908 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 4/88 103/9376 4.13768755516328 COL4A2/COL4A1/LAMA2/FN1 3.11662140134247 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 5/88 157/9376 3.39316734221193 MT-CYB/MT-CO3/MT-CO1/MT-CO2/FOS 2.94338354308918 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 3/88 59/9376 5.4175654853621 CGA/FABP4/GNAI2 3.31311739842952 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 4/88 112/9376 3.8051948051948 LAMA2/HSPA6/HSPA8/GNAI2 2.90695718300897 Organismal Systems Immune system hsa04611 Platelet activation 4/88 126/9376 3.38239538239538 FCGR2A/MYL12B/ACTB/GNAI2 2.62056004856026 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 3/88 76/9376 4.20574162679426 FABP4/CD36/SORBS1 2.73123902613397 Organismal Systems Digestive system hsa04971 Gastric acid secretion 3/88 76/9376 4.20574162679426 EZR/ACTB/GNAI2 2.73123902613397 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 7/88 333/9376 2.23969423969424 COL4A2/COL4A1/LAMA2/THBS1/JAG1/FN1/COL6A1 2.24205522396211 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 3/88 78/9376 4.0979020979021 FN1/ACTB/CTTN 2.67415200596393 Human Diseases Infectious disease: viral hsa05162 Measles 4/88 136/9376 3.13368983957219 FCGR2B/HSPA6/HSPA8/FOS 2.43966743175602 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 4/88 138/9376 3.08827404479578 FCGR2A/FN1/ACTB/FOS 2.40549204938161 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 4/88 140/9376 3.04415584415584 GNGT1/JAG1/APLNR/GNAI2 2.3719303354569 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 5/88 204/9376 2.61140819964349 EZR/THBS1/FN1/ACTB/CTTN 2.26492852188921 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 4/88 144/9376 2.95959595959596 ID3/SMAD9/ID1/ID2 2.30656530092999 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 5/88 214/9376 2.48937977909941 GNGT1/BST2/FOS/CALR/GNAI2 2.14527547116138 Organismal Systems Nervous system hsa04727 GABAergic synapse 3/88 89/9376 3.59141981613892 GNGT1/GLUL/GNAI2 2.39089732917404 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 5/88 217/9376 2.45496439044826 HSP90AB1/JAG1/HSP90B1/FOS/GNAI2 2.11068815355872 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 3/88 91/9376 3.51248751248751 FCGR2B/CD81/FOS 2.34422625107583 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 4/88 154/9376 2.76741440377804 MYL6/ACTB/FOS/GNAI2 2.15254412291567 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 3/88 93/9376 3.43695014662757 MYL12B/SORBS1/ACTB 2.29884566098154 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 3/88 94/9376 3.40038684719536 HSP90AB1/HSP90B1/FOS 2.27661846555742 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 5/88 224/9376 2.37824675324675 SLC2A1/FDPS/FOS/CALR/ZFP36 2.03216446281366 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 4/88 157/9376 2.71453387376954 ID1/ACTB/BMP6/ID2 2.108724575632 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 2/88 43/9376 4.95560253699789 SCARB1/CD36 2.53047535847439 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 3/88 97/9376 3.29522024367385 GNGT1/FOS/GNAI2 2.21169642722829 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 3/88 101/9376 3.16471647164716 COL4A2/COL4A1/FN1 2.12897528807663 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 3/88 103/9376 3.10326566637246 FOS/CALR/GNAI2 2.0891445286636 NA NA hsa03272 Virion - Hepatitis viruses 2/88 48/9376 4.43939393939394 SCARB1/CD81 2.32527403726333 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 3/88 110/9376 2.90578512396694 EPAS1/SLC2A1/GAPDH 1.95699627133485 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 2/88 52/9376 4.0979020979021 SCARB1/CD36 2.18038958591047 Metabolism Energy metabolism hsa00920 Sulfur metabolism 1/88 10/9376 10.6545454545455 PAPSS2 2.97317605018343 Organismal Systems Nervous system hsa04725 Cholinergic synapse 3/88 115/9376 2.77944664031621 GNGT1/FOS/GNAI2 1.86883439494396 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 3/88 115/9376 2.77944664031621 LRP6/FOS/GNAI2 1.86883439494396 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 3/88 116/9376 2.75548589341693 GNGT1/GLUL/GNAI2 1.85176860228453 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 2/88 56/9376 3.8051948051948 HSPA6/HSPA8 2.04934442296085 Genetic Information Processing Information processing in viruses hsa03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus 1/88 12/9376 8.87878787878788 FCGR2B 2.65818497882564 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 2/88 62/9376 3.43695014662757 HSPA6/HSPA8 1.87387338836048 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/88 65/9376 3.27832167832168 KISS1/CGA 1.79407018309147 Metabolism Lipid metabolism hsa00140 Steroid hormone biosynthesis 2/88 66/9376 3.22865013774105 HSD17B2/CYP19A1 1.76849931024524 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 3/88 133/9376 2.40328092959672 GNGT1/FOS/GNAI2 1.58646259934704 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 6/88 370/9376 1.72776412776413 CSH1/KISS1/CSH2/CSHL1/CGA/APLNR 1.39024520734868 Cellular Processes Cell growth and death hsa04210 Apoptosis 3/88 137/9376 2.33311214333112 SPTAN1/ACTB/FOS 1.52996098218099 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 4/88 212/9376 2.01029159519726 ID1/THBS1/ACTB/GNAI2 1.44823153902199 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 2/88 70/9376 3.04415584415584 SLC2A1/CD36 1.67088811410112 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 2/88 70/9376 3.04415584415584 EPAS1/SLC2A1 1.67088811410112 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/88 70/9376 3.04415584415584 LAMA2/ACTB 1.67088811410112 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/88 71/9376 3.00128040973111 CGA/FOS 1.64757351002441 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 2/88 71/9376 3.00128040973111 JAM3/JAM2 1.64757351002441 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 5/88 298/9376 1.78767541183649 CSH1/CSH2/CSHL1/BMP6/CCL23 1.34501213432604 Metabolism Metabolism of other amino acids hsa00450 Selenocompound metabolism 1/88 17/9376 6.26737967914438 PAPSS2 2.11577865732635 Metabolism Energy metabolism hsa00910 Nitrogen metabolism 1/88 17/9376 6.26737967914438 GLUL 2.11577865732635 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 3/88 142/9376 2.25096030729834 FCGR2B/FCGR2A/FOS 1.46203792347391 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 2/88 73/9376 2.91905354919054 BST2/BICD1 1.60214892946157 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 2/88 75/9376 2.84121212121212 GLUL/GAPDH 1.55824415216477 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 2/88 75/9376 2.84121212121212 CGA/HSP90B1 1.55824415216477 Human Diseases Cancer: specific types hsa05224 Breast cancer 3/88 148/9376 2.15970515970516 JAG1/LRP6/FOS 1.38417348302679 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/88 78/9376 2.73193473193473 FOS/GNAI2 1.49503005299564 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/88 78/9376 2.73193473193473 FCGR2A/FOS 1.49503005299564 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 4/88 232/9376 1.83699059561129 EZR/MYL12B/FN1/ACTB 1.25649953720509 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 3/88 160/9376 1.99772727272727 PECAM1/JAM3/JAM2 1.23898621079286 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 2/88 86/9376 2.47780126849894 LAMA2/ACTB 1.34005700879435 Metabolism Amino acid metabolism hsa00220 Arginine biosynthesis 1/88 23/9376 4.63241106719368 GLUL 1.6976545116047 Metabolism Metabolism of terpenoids and polyketides hsa00900 Terpenoid backbone biosynthesis 1/88 23/9376 4.63241106719368 FDPS 1.6976545116047 Organismal Systems Digestive system hsa04976 Bile secretion 2/88 90/9376 2.36767676767677 SCARB1/SLC2A1 1.26898431964264 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 3/88 168/9376 1.9025974025974 CSH1/CSH2/CSHL1 1.14903150293341 Human Diseases Substance dependence hsa05032 Morphine addiction 2/88 91/9376 2.34165834165834 GNGT1/GNAI2 1.25180749709536 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/88 93/9376 2.29130009775171 JAG1/FOS 1.21812078546194 Organismal Systems Digestive system hsa04977 Vitamin digestion and absorption 1/88 26/9376 4.0979020979021 SCARB1 1.53962313450624 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 2/88 98/9376 2.17439703153989 FCGR2B/FCGR2A 1.13753998046196 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 2/88 99/9376 2.1524334251607 JAG1/FOS 1.12200692135057 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 2/88 99/9376 2.1524334251607 FCGR2B/FCGR2A 1.12200692135057 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 2/88 99/9376 2.1524334251607 LAMA2/ACTB 1.12200692135057 Organismal Systems Sensory system hsa04744 Phototransduction 1/88 29/9376 3.67398119122257 GNGT1 1.40374136136004 Organismal Systems Development and regeneration hsa04360 Axon guidance 3/88 184/9376 1.73715415019763 ABLIM3/MYL12B/GNAI2 0.98294244624957 Metabolism Carbohydrate metabolism hsa00630 Glyoxylate and dicarboxylate metabolism 1/88 31/9376 3.43695014662757 GLUL 1.32282900762055 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 2/88 105/9376 2.02943722943723 LAMA2/ACTB 1.03251673709142 Human Diseases Cancer: specific types hsa05215 Prostate cancer 2/88 106/9376 2.01029159519726 HSP90AB1/HSP90B1 1.01818261291788 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 3/88 193/9376 1.65614696184644 GNGT1/GNAI2/CCL23 0.89650632001443 Organismal Systems Immune system hsa04659 Th17 cell differentiation 2/88 109/9376 1.95496246872394 HSP90AB1/FOS 0.976103436905703 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 2/88 109/9376 1.95496246872394 SLC2A1/CD36 0.976103436905703 Cellular Processes Cell motility hsa04814 Motor proteins 3/88 194/9376 1.64761012183693 MYL12B/MYL6/ACTB 0.887179952619262 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 2/88 110/9376 1.93719008264463 HSP90AB1/GNAI2 0.962373708453477 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 3/88 196/9376 1.63079777365492 GNGT1/FOS/ZFP36 0.868685790959711 Organismal Systems Nervous system hsa04726 Serotonergic synapse 2/88 115/9376 1.85296442687747 GNGT1/GNAI2 0.895811777940706 Metabolism Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism 1/88 37/9376 2.87960687960688 GLUL 1.11502234617157 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 1/88 37/9376 2.87960687960688 IDO2 1.11502234617157 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 2/88 119/9376 1.79067990832697 JAG1/FOS 0.844899246860372 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/88 122/9376 1.74664679582712 SLC2A1/ACTB 0.807971876576402 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/88 41/9376 2.59866962305987 THBS1 0.998525961579464 Metabolism Amino acid metabolism hsa00380 Tryptophan metabolism 1/88 42/9376 2.53679653679654 IDO2 0.971567527401089 NA NA hsa04382 Cornified envelope formation 3/88 217/9376 1.47297863426896 COL4A2/COL4A1/S100A6 0.686140778971435 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/88 44/9376 2.42148760330579 TUSC3 0.919915466476565 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 3/88 226/9376 1.41432019308126 CGA/FOS/GNAI2 0.613685191727161 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 3/88 227/9376 1.40808970764918 GNGT1/CALR/GNAI2 0.605825608738591 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 4/88 323/9376 1.31944835350408 ZFPM2/EZR/THBS1/VIM 0.568684676247723 Human Diseases Substance dependence hsa05030 Cocaine addiction 1/88 49/9376 2.17439703153989 GNAI2 0.802246567090366 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 1/88 50/9376 2.13090909090909 AMD1 0.780424442312016 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/88 51/9376 2.0891265597148 ACTB 0.759110306130796 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 3/88 238/9376 1.34300993124523 FCGR2A/FOS/RPL38 0.521717575080335 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 1/88 54/9376 1.97306397306397 AMD1 0.697990633820597 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/88 54/9376 1.97306397306397 CGA 0.697990633820597 Metabolism Lipid metabolism hsa00600 Sphingolipid metabolism 1/88 55/9376 1.93719008264463 PSAP 0.678490304276679 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 1/88 56/9376 1.9025974025974 TUSC3 0.659395543498979 Cellular Processes Transport and catabolism hsa04144 Endocytosis 3/88 250/9376 1.27854545454545 HSPA6/PSD3/HSPA8 0.434501938966511 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 3/88 253/9376 1.26338483650737 MYL12B/ACTB/CTTN 0.413378668802704 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 2/88 155/9376 1.37478005865103 SCARB1/GNAI2 0.457951181490843 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 2/88 156/9376 1.36596736596737 SCARB1/CD81 0.448647311687095 Organismal Systems Nervous system hsa04730 Long-term depression 1/88 60/9376 1.77575757575758 GNAI2 0.586749572170525 Organismal Systems Digestive system hsa04978 Mineral absorption 1/88 61/9376 1.74664679582712 MT2A 0.569448645800148 Environmental Information Processing Signal transduction hsa04330 Notch signaling pathway 1/88 62/9376 1.71847507331378 JAG1 0.552465680082212 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 1/88 65/9376 1.63916083916084 SCARB1 0.503308823617435 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 1/88 67/9376 1.59023066485753 GAPDH 0.471925588648215 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/88 168/9376 1.26839826839827 HSP90AB1/GLUL 0.341678432526962 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 2/88 170/9376 1.25347593582888 ACTB/LRP6 0.324632189923384 Organismal Systems Endocrine system hsa04924 Renin secretion 1/88 69/9376 1.54413702239789 GNAI2 0.441564179196502 Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/88 69/9376 1.54413702239789 FOS 0.441564179196502 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/88 173/9376 1.23173935890699 FDPS/ACTB 0.299449789852463 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/88 71/9376 1.50064020486556 SLC2A1 0.412156904938929 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 2/88 180/9376 1.18383838383838 BST2/CALR 0.242403471728142 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/88 75/9376 1.42060606060606 THBS1 0.355964924819734 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/88 181/9376 1.17729784028127 FCGR2B/FCGR2A 0.23444055288666 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/88 187/9376 1.13952357802625 HSP90AB1/TXNIP 0.187585883661725 NA NA hsa04519 Cadherin signaling 4/88 404/9376 1.05490549054905 CDH13/ACTB/LRP6/VIM 0.109806411032594 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 3/88 300/9376 1.06545454545455 HSPA6/HSPA8/FOS 0.112155110073404 Human Diseases Substance dependence hsa05034 Alcoholism 2/88 191/9376 1.11565920990005 GNGT1/GNAI2 0.157189377985591 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 2/88 195/9376 1.09277389277389 FCGR2A/ACTB 0.12742773473524 Organismal Systems Endocrine system hsa04911 Insulin secretion 1/88 86/9376 1.23890063424947 SLC2A1 0.216632964225696 NA NA hsa04082 Neuroactive ligand signaling 2/88 199/9376 1.07080858839653 GNGT1/GNAI2 0.0982715893263361 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/88 87/9376 1.22466039707419 FOS 0.204912068763603 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/88 88/9376 1.21074380165289 CLU 0.19333074020885 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 1/88 89/9376 1.19713993871297 GNAI2 0.181885370331332 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/88 90/9376 1.18383838383838 FOS 0.170572486096721 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 2/88 205/9376 1.03946784922395 CALR/VIM 0.0556132038309493 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/88 93/9376 1.14565004887586 CGA 0.137395909942338 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/88 95/9376 1.12153110047847 FOS 0.115882463126587 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/88 98/9376 1.08719851576994 SCARB1 0.084461894283905 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/88 99/9376 1.07621671258035 FOS 0.0742044418104362 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/88 100/9376 1.06545454545455 CCL23 0.0640509111590347 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/88 100/9376 1.06545454545455 CD36 0.0640509111590347 Organismal Systems Endocrine system hsa04916 Melanogenesis 1/88 101/9376 1.05490549054905 GNAI2 0.0539989574106756 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 1/88 107/9376 0.995751911639762 SLC2A1 -0.00430164790677812 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/88 109/9376 0.977481234361968 FOS -0.0230172862851127 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/88 116/9376 0.918495297805643 GAPDH -0.085974970820353 Genetic Information Processing Transcription hsa03040 Spliceosome 2/88 243/9376 0.876917321361766 HSPA6/HSPA8 -0.189216592864638 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 1/88 117/9376 0.910644910644911 ACTB -0.0946664416821875 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/88 122/9376 0.873323397913562 CD36 -0.13708105690418 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/88 122/9376 0.873323397913562 FOS -0.13708105690418 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/88 125/9376 0.852363636363636 GNAI2 -0.16174090792852 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 1/88 128/9376 0.832386363636364 PAPSS2 -0.185847315977356 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/88 134/9376 0.795115332428765 MYL6 -0.232511665703527 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/88 138/9376 0.772068511198946 SORBS1 -0.262555283623355 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/88 143/9376 0.745073108709472 FCGR2A -0.29900477358893 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/88 150/9376 0.71030303030303 LRP6 -0.348135833768514 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/88 154/9376 0.69185360094451 IDO2 -0.375293263915157 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 1/88 154/9376 0.69185360094451 GNAI2 -0.375293263915157 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/88 158/9376 0.67433831990794 LRP6 -0.401830336973663 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/88 163/9376 0.653653095370887 FOS -0.434180633672424 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/88 166/9376 0.64184008762322 GNAI2 -0.45317618073023 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/88 178/9376 0.598569969356486 LRP6 -0.526306856695174 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/88 201/9376 0.530076888285843 ID2 -0.655522598462212 Genetic Information Processing Translation hsa03010 Ribosome 1/88 222/9376 0.47993447993448 RPL38 -0.763299478100361 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/88 238/9376 0.447669977081742 GNGT1 -0.840093110875462 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/88 250/9376 0.426181818181818 PSAP -0.895096683667304