ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/139 68/18639 0.132352941176471 17.7476724502751 1.86485771395863e-09 7.75780809006792e-07 GO:0005201 extracellular matrix structural constituent 12/139 168/18639 0.0714285714285714 9.57810894141829 4.79895603872358e-09 9.98182856054505e-07 GO:0009055 electron transfer activity 10/139 116/18639 0.0862068965517241 11.5597866534359 1.59944412131626e-08 2.21789584822521e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 9/139 118/18639 0.076271186440678 10.2274722594806 2.47035086452972e-07 2.56916489911091e-05 GO:0015078 proton transmembrane transporter activity 10/139 185/18639 0.0540540540540541 7.2482986583706 1.28189778720289e-06 0.00010665389589528 GO:0015399 primary active transmembrane transporter activity 9/139 166/18639 0.0542168674698795 7.27013088324521 4.32292843917831e-06 0.000299723038449696 GO:0030169 low-density lipoprotein particle binding 4/139 17/18639 0.235294117647059 31.5514176893779 6.53737286417589e-06 0.000388506730213882 GO:0008137 NADH dehydrogenase (ubiquinone) activity 5/139 41/18639 0.121951219512195 16.3528689243727 1.29586082896712e-05 0.000673847631062905 GO:0003954 NADH dehydrogenase activity 5/139 44/18639 0.113636363636364 15.23790058862 1.84452980523726e-05 0.000767324398978701 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/139 44/18639 0.113636363636364 15.23790058862 1.84452980523726e-05 0.000767324398978701 GO:0050431 transforming growth factor beta binding 4/139 24/18639 0.166666666666667 22.3489208633094 2.80274133959462e-05 0.00105994581570124 GO:0005131 growth hormone receptor binding 3/139 10/18639 0.3 40.2280575539568 4.68737053016e-05 0.00162495511712213 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/139 58/18639 0.0862068965517241 11.5597866534359 7.15802434729145e-05 0.00229056779113326 GO:0071813 lipoprotein particle binding 4/139 32/18639 0.125 16.761690647482 9.05596646657286e-05 0.00251152136672954 GO:0071814 protein-lipid complex binding 4/139 32/18639 0.125 16.761690647482 9.05596646657286e-05 0.00251152136672954 GO:0140416 transcription regulator inhibitor activity 4/139 33/18639 0.121212121212121 16.2537606278614 0.000102456813826271 0.00266387715948303 GO:0051427 hormone receptor binding 4/139 34/18639 0.117647058823529 15.775708844689 0.000115448723229625 0.00282509816844259 GO:0004129 cytochrome-c oxidase activity 3/139 15/18639 0.2 26.8187050359712 0.000172932573088929 0.00397479650529765 GO:0045296 cadherin binding 10/139 334/18639 0.029940119760479 4.0147762029897 0.000206330574060962 0.00397479650529765 GO:0005178 integrin binding 7/139 161/18639 0.0434782608695652 5.8301532686894 0.000206950271397706 0.00397479650529765 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/139 16/18639 0.1875 25.142535971223 0.00021167972713984 0.00397479650529765 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/139 16/18639 0.1875 25.142535971223 0.00021167972713984 0.00397479650529765 GO:0140662 ATP-dependent protein folding chaperone 4/139 40/18639 0.1 13.4093525179856 0.000219760383706361 0.00397479650529765 GO:0044183 protein folding chaperone 5/139 75/18639 0.0666666666666667 8.93956834532374 0.00024363479146708 0.00422300305209606 GO:0051082 unfolded protein binding 6/139 121/18639 0.0495867768595041 6.64926571139782 0.000293868566274504 0.00488152387345312 GO:0030228 lipoprotein particle receptor activity 3/139 18/18639 0.166666666666667 22.3489208633094 0.00030509524209082 0.00488152387345312 GO:0015245 fatty acid transmembrane transporter activity 3/139 19/18639 0.157894736842105 21.1726618705036 0.000360327375703534 0.00555171067750631 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/139 88/18639 0.0568181818181818 7.61895029431001 0.000511855445214563 0.00760470947175922 GO:0019838 growth factor binding 6/139 136/18639 0.0441176470588235 5.91589081675836 0.000548607197804272 0.00786967566505438 GO:0170055 lipid transmembrane transporter activity 4/139 56/18639 0.0714285714285714 9.57810894141829 0.000805441508834997 0.011168788922512 GO:0023026 MHC class II protein complex binding 3/139 27/18639 0.111111111111111 14.8992805755396 0.00104124674826556 0.0139728595896281 GO:0097718 disordered domain specific binding 3/139 28/18639 0.107142857142857 14.3671634121274 0.00115986400472128 0.0150782320613767 GO:0008083 growth factor activity 6/139 162/18639 0.037037037037037 4.96642685851319 0.00136345552842061 0.0171878030249386 GO:0005200 structural constituent of cytoskeleton 5/139 112/18639 0.0446428571428571 5.98631808838643 0.00152021206963159 0.0186002417931394 GO:0005518 collagen binding 4/139 72/18639 0.0555555555555556 7.44964028776978 0.00205809917233185 0.0244619787340014 GO:0022804 active transmembrane transporter activity 10/139 457/18639 0.0218818380743982 2.93421280481086 0.00227558526682972 0.0262956519722545 GO:0098631 cell adhesion mediator activity 4/139 76/18639 0.0526315789473684 7.05755395683453 0.00250846951421794 0.0281126620580453 GO:0023023 MHC protein complex binding 3/139 37/18639 0.0810810810810811 10.8724479875559 0.00261962460961147 0.0281126620580453 GO:0042277 peptide binding 7/139 249/18639 0.0281124497991968 3.76969749501604 0.00267532259990958 0.0281126620580453 GO:0033293 monocarboxylic acid binding 4/139 79/18639 0.0506329113924051 6.78954557872689 0.00288768397980266 0.0281126620580453 GO:0019864 IgG binding 2/139 11/18639 0.181818181818182 24.380640941792 0.00290587612619218 0.0281126620580453 GO:0034713 type I transforming growth factor beta receptor binding 2/139 11/18639 0.181818181818182 24.380640941792 0.00290587612619218 0.0281126620580453 GO:0048407 platelet-derived growth factor binding 2/139 11/18639 0.181818181818182 24.380640941792 0.00290587612619218 0.0281126620580453 GO:0001540 amyloid-beta binding 4/139 83/18639 0.0481927710843374 6.46233856288463 0.0034518952594812 0.032636100635095 GO:0048156 tau protein binding 3/139 43/18639 0.0697674418604651 9.35536222185043 0.0040275563972867 0.0369063338902233 GO:0008035 high-density lipoprotein particle binding 2/139 13/18639 0.153846153846154 20.6297731045933 0.00408098884363046 0.0369063338902233 GO:0019955 cytokine binding 5/139 144/18639 0.0347222222222222 4.65602517985612 0.00451210487984515 0.0399369282982039 GO:0019763 immunoglobulin receptor activity 2/139 14/18639 0.142857142857143 19.1562178828366 0.0047379695373586 0.0402243944396159 GO:0044548 S100 protein binding 2/139 14/18639 0.142857142857143 19.1562178828366 0.0047379695373586 0.0402243944396159 GO:0005041 low-density lipoprotein particle receptor activity 2/139 15/18639 0.133333333333333 17.8791366906475 0.00544028291647702 0.0452631538650888 GO:0070411 I-SMAD binding 2/139 16/18639 0.125 16.761690647482 0.00618722622923948 0.0504683551247769 GO:0098632 cell-cell adhesion mediator activity 3/139 55/18639 0.0545454545454545 7.31419228253761 0.0080243160269271 0.0641945282154168 GO:0001786 phosphatidylserine binding 3/139 59/18639 0.0508474576271186 6.8183148396537 0.00973126249133907 0.0763812301206991 GO:0001846 opsonin binding 2/139 21/18639 0.0952380952380952 12.7708119218911 0.0105673392509245 0.0802665587455127 GO:0033218 amide binding 6/139 247/18639 0.0242914979757085 3.25733259546209 0.0106121652187577 0.0802665587455127 GO:0140297 DNA-binding transcription factor binding 9/139 488/18639 0.0184426229508197 2.47303632503833 0.0110037935522706 0.0817424663882961 GO:0008093 cytoskeletal anchor activity 2/139 22/18639 0.0909090909090909 12.190320470896 0.0115677374905004 0.0844241894043539 GO:0038024 cargo receptor activity 3/139 65/18639 0.0461538461538462 6.18893193137797 0.0126599349546686 0.0907083925398264 GO:0004857 enzyme inhibitor activity 8/139 416/18639 0.0192307692307692 2.57872163807416 0.0128648922111773 0.0907083925398264 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/139 24/18639 0.0833333333333333 11.1744604316547 0.0136876687108489 0.0936758704978318 GO:0050840 extracellular matrix binding 3/139 67/18639 0.0447761194029851 6.00418769462042 0.0137361252412686 0.0936758704978318 GO:0001848 complement binding 2/139 25/18639 0.08 10.7274820143885 0.0148059244901322 0.0991085906989159 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/139 70/18639 0.0428571428571429 5.74686536485098 0.0154453027875341 0.0991085906989159 GO:0005160 transforming growth factor beta receptor binding 2/139 26/18639 0.0769230769230769 10.3148865522966 0.015962200905835 0.0991085906989159 GO:0019865 immunoglobulin binding 2/139 26/18639 0.0769230769230769 10.3148865522966 0.015962200905835 0.0991085906989159 GO:0050750 low-density lipoprotein particle receptor binding 2/139 26/18639 0.0769230769230769 10.3148865522966 0.015962200905835 0.0991085906989159 GO:0070412 R-SMAD binding 2/139 26/18639 0.0769230769230769 10.3148865522966 0.015962200905835 0.0991085906989159 GO:0031072 heat shock protein binding 4/139 131/18639 0.0305343511450382 4.09445878411774 0.0167549749666966 0.100825195966199 GO:0005044 scavenger receptor activity 2/139 27/18639 0.0740740740740741 9.93285371702638 0.0171558772384406 0.100825195966199 GO:0005179 hormone activity 4/139 132/18639 0.0303030303030303 4.06344015696534 0.0171812457822248 0.100825195966199 GO:0005126 cytokine receptor binding 6/139 275/18639 0.0218181818181818 2.92567691301504 0.0172081464269234 0.100825195966199 GO:0051087 protein-folding chaperone binding 4/139 134/18639 0.0298507462686567 4.00279179641362 0.0180540111862696 0.103190111112059 GO:0003779 actin binding 8/139 443/18639 0.018058690744921 2.4215535021193 0.0181078800749527 0.103190111112059 GO:0003714 transcription corepressor activity 5/139 204/18639 0.0245098039215686 3.2866060093102 0.0184950446575123 0.103972142939529 GO:0033612 receptor serine/threonine kinase binding 2/139 30/18639 0.0666666666666667 8.93956834532374 0.0209552035256454 0.116231528888913 GO:0046332 SMAD binding 3/139 79/18639 0.0379746835443038 5.09215918404517 0.0212629716203552 0.116386792027208 GO:0070325 lipoprotein particle receptor binding 2/139 31/18639 0.0645161290322581 8.65119517289394 0.0222924118278847 0.120436926238962 GO:0001618 virus receptor activity 3/139 81/18639 0.037037037037037 4.96642685851319 0.0226972013574936 0.121051740573299 GO:0140272 exogenous protein binding 3/139 82/18639 0.0365853658536585 4.90586067731181 0.0234336378968935 0.123397384368452 GO:0001664 G protein-coupled receptor binding 6/139 297/18639 0.0202020202020202 2.70896010464356 0.0240549892776908 0.125085944243992 GO:0031625 ubiquitin protein ligase binding 6/139 302/18639 0.0198675496688742 2.66410977178522 0.0258333612625697 0.132675040558383 GO:0061134 peptidase regulator activity 5/139 226/18639 0.0221238938053097 2.96667091105876 0.0272884376122137 0.138438903008304 GO:0072341 modified amino acid binding 3/139 91/18639 0.032967032967033 4.42066566526998 0.0306400862638055 0.153569588984856 GO:0043394 proteoglycan binding 2/139 37/18639 0.0540540540540541 7.2482986583706 0.0310180138290606 0.153613020867729 GO:0004866 endopeptidase inhibitor activity 4/139 161/18639 0.0248447204968944 3.3315161535368 0.0325695340043457 0.159399131127151 GO:0042562 hormone binding 3/139 94/18639 0.0319148936170213 4.27958059084647 0.0332725164488373 0.160946126078097 GO:0044389 ubiquitin-like protein ligase binding 6/139 322/18639 0.0186335403726708 2.4986371151526 0.0338179542196648 0.161704240866443 GO:0005539 glycosaminoglycan binding 5/139 242/18639 0.0206611570247934 2.77052737974909 0.0351183849628376 0.166014183460687 GO:0030414 peptidase inhibitor activity 4/139 169/18639 0.0236686390532544 3.1738112468605 0.0378772537211191 0.177044242112197 GO:0019894 kinesin binding 2/139 42/18639 0.0476190476190476 6.38540596094553 0.0391478438907076 0.180950033983715 GO:0008201 heparin binding 4/139 172/18639 0.0232558139534884 3.11845407395014 0.0399883884510874 0.182804061490685 GO:0005319 lipid transporter activity 4/139 178/18639 0.0224719101123595 3.01333764449115 0.0444086110257253 0.20080415420328 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/139 349/18639 0.0171919770773639 2.305332811115 0.046913466273589 0.209849483546377 GO:0005504 fatty acid binding 2/139 47/18639 0.0425531914893617 5.70610745446196 0.0479874366065283 0.212369932216125 GO:0061135 endopeptidase regulator activity 4/139 184/18639 0.0217391304347826 2.9150766343447 0.0490925563062882 0.213271539344335 GO:0004222 metalloendopeptidase activity 3/139 110/18639 0.0272727272727273 3.6570961412688 0.049216509079462 0.213271539344335 GO:0038187 pattern recognition receptor activity 2/139 48/18639 0.0416666666666667 5.58723021582734 0.0498349780823506 0.2137252668274 GO:0031406 carboxylic acid binding 4/139 187/18639 0.0213903743315508 2.86831069903436 0.0515331578518073 0.218752996595427 GO:0043177 organic acid binding 4/139 189/18639 0.0211640211640212 2.83795820486468 0.0531966358643259 0.22353333858141 GO:0140313 molecular sequestering activity 2/139 55/18639 0.0363636363636364 4.8761281883584 0.0634528647299529 0.263963917276604 GO:0005522 profilin binding 1/139 10/18639 0.1 13.4093525179856 0.0721381470780178 0.288552588312071 GO:0019911 structural constituent of myelin sheath 1/139 10/18639 0.1 13.4093525179856 0.0721381470780178 0.288552588312071 GO:0030957 Tat protein binding 1/139 10/18639 0.1 13.4093525179856 0.0721381470780178 0.288552588312071 GO:0043208 glycosphingolipid binding 1/139 10/18639 0.1 13.4093525179856 0.0721381470780178 0.288552588312071 GO:0015026 coreceptor activity 2/139 61/18639 0.0327868852459016 4.39650902229036 0.0759972590696614 0.293656532643315 GO:0005114 type II transforming growth factor beta receptor binding 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0019215 intermediate filament binding 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0042608 T cell receptor binding 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0048185 activin binding 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0050998 nitric-oxide synthase binding 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0070697 activin receptor binding 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/139 11/18639 0.0909090909090909 12.190320470896 0.0790613741732001 0.293656532643315 GO:0002020 protease binding 3/139 136/18639 0.0220588235294118 2.95794540837918 0.0815666124981892 0.300280626542006 GO:0004859 phospholipase inhibitor activity 1/139 12/18639 0.0833333333333333 11.1744604316547 0.0859333125986846 0.300405529756746 GO:0005049 nuclear export signal receptor activity 1/139 12/18639 0.0833333333333333 11.1744604316547 0.0859333125986846 0.300405529756746 GO:0015132 prostaglandin transmembrane transporter activity 1/139 12/18639 0.0833333333333333 11.1744604316547 0.0859333125986846 0.300405529756746 GO:0034452 dynactin binding 1/139 12/18639 0.0833333333333333 11.1744604316547 0.0859333125986846 0.300405529756746 GO:0070410 co-SMAD binding 1/139 12/18639 0.0833333333333333 11.1744604316547 0.0859333125986846 0.300405529756746 GO:1990459 transferrin receptor binding 1/139 12/18639 0.0833333333333333 11.1744604316547 0.0859333125986846 0.300405529756746 GO:0020037 heme binding 3/139 142/18639 0.0211267605633803 2.83296179957442 0.0900674280255687 0.312233750488638 GO:0035325 Toll-like receptor binding 1/139 13/18639 0.0769230769230769 10.3148865522966 0.0927543395782726 0.313705733858223 GO:0070700 BMP receptor binding 1/139 13/18639 0.0769230769230769 10.3148865522966 0.0927543395782726 0.313705733858223 GO:0071714 icosanoid transmembrane transporter activity 1/139 13/18639 0.0769230769230769 10.3148865522966 0.0927543395782726 0.313705733858223 GO:0097110 scaffold protein binding 2/139 70/18639 0.0285714285714286 3.83124357656732 0.0961138472080721 0.316048313785272 GO:0005125 cytokine activity 4/139 234/18639 0.0170940170940171 2.29219701162147 0.0980801331480907 0.316048313785272 GO:0005545 1-phosphatidylinositol binding 1/139 14/18639 0.0714285714285714 9.57810894141829 0.0995248295814198 0.316048313785272 GO:0008191 metalloendopeptidase inhibitor activity 1/139 14/18639 0.0714285714285714 9.57810894141829 0.0995248295814198 0.316048313785272 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/139 14/18639 0.0714285714285714 9.57810894141829 0.0995248295814198 0.316048313785272 GO:0032036 myosin heavy chain binding 1/139 14/18639 0.0714285714285714 9.57810894141829 0.0995248295814198 0.316048313785272 GO:0034236 protein kinase A catalytic subunit binding 1/139 14/18639 0.0714285714285714 9.57810894141829 0.0995248295814198 0.316048313785272 GO:0043176 amine binding 1/139 14/18639 0.0714285714285714 9.57810894141829 0.0995248295814198 0.316048313785272 GO:0046906 tetrapyrrole binding 3/139 152/18639 0.0197368421052632 2.64658273381295 0.10501441903585 0.327392475605717 GO:0048029 monosaccharide binding 2/139 74/18639 0.027027027027027 3.6241493291853 0.105491004526783 0.327392475605717 GO:0005523 tropomyosin binding 1/139 15/18639 0.0666666666666667 8.93956834532374 0.106245154343201 0.327392475605717 GO:0140776 protein-containing complex destabilizing activity 1/139 15/18639 0.0666666666666667 8.93956834532374 0.106245154343201 0.327392475605717 GO:0003725 double-stranded RNA binding 2/139 75/18639 0.0266666666666667 3.5758273381295 0.107872977306415 0.329964401172564 GO:0005024 transforming growth factor beta receptor activity 1/139 16/18639 0.0625 8.38084532374101 0.112915682884132 0.335010208561448 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/139 16/18639 0.0625 8.38084532374101 0.112915682884132 0.335010208561448 GO:0055102 lipase inhibitor activity 1/139 16/18639 0.0625 8.38084532374101 0.112915682884132 0.335010208561448 GO:0019199 transmembrane receptor protein kinase activity 2/139 78/18639 0.0256410256410256 3.43829551743221 0.11510376423503 0.335010208561448 GO:0004659 prenyltransferase activity 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0019198 transmembrane receptor protein phosphatase activity 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0036041 long-chain fatty acid binding 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0048038 quinone binding 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0051787 misfolded protein binding 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:1990226 histone methyltransferase binding 1/139 17/18639 0.0588235294117647 7.88785442234448 0.119536781529845 0.335010208561448 GO:0048306 calcium-dependent protein binding 2/139 80/18639 0.025 3.3523381294964 0.119991637201095 0.335010208561448 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/139 18/18639 0.0555555555555556 7.44964028776978 0.126108813930626 0.342884095393076 GO:0034185 apolipoprotein binding 1/139 18/18639 0.0555555555555556 7.44964028776978 0.126108813930626 0.342884095393076 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/139 18/18639 0.0555555555555556 7.44964028776978 0.126108813930626 0.342884095393076 GO:0098641 cadherin binding involved in cell-cell adhesion 1/139 18/18639 0.0555555555555556 7.44964028776978 0.126108813930626 0.342884095393076 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/139 19/18639 0.0526315789473684 7.05755395683453 0.132632141080814 0.355967552836249 GO:0097001 ceramide binding 1/139 19/18639 0.0526315789473684 7.05755395683453 0.132632141080814 0.355967552836249 GO:0001972 retinoic acid binding 1/139 20/18639 0.05 6.70467625899281 0.139107121338051 0.368589569914836 GO:0015095 magnesium ion transmembrane transporter activity 1/139 20/18639 0.05 6.70467625899281 0.139107121338051 0.368589569914836 GO:0008514 organic anion transmembrane transporter activity 4/139 269/18639 0.0148698884758364 1.99395576475622 0.141971493911337 0.373717221876799 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/139 21/18639 0.0476190476190476 6.38540596094553 0.145534110442407 0.373717221876799 GO:0036122 BMP binding 1/139 21/18639 0.0476190476190476 6.38540596094553 0.145534110442407 0.373717221876799 GO:0070182 DNA polymerase binding 1/139 21/18639 0.0476190476190476 6.38540596094553 0.145534110442407 0.373717221876799 GO:0072542 protein phosphatase activator activity 1/139 21/18639 0.0476190476190476 6.38540596094553 0.145534110442407 0.373717221876799 GO:1901681 sulfur compound binding 4/139 275/18639 0.0145454545454545 1.95045127534336 0.150176526042009 0.383272606340342 GO:0031683 G-protein beta/gamma-subunit complex binding 1/139 22/18639 0.0454545454545455 6.09516023544801 0.151913461535356 0.385341463406756 GO:0030246 carbohydrate binding 4/139 280/18639 0.0142857142857143 1.91562178828366 0.157150912977816 0.385586702356094 GO:0005158 insulin receptor binding 1/139 23/18639 0.0434782608695652 5.8301532686894 0.158245525178617 0.385586702356094 GO:0005212 structural constituent of eye lens 1/139 23/18639 0.0434782608695652 5.8301532686894 0.158245525178617 0.385586702356094 GO:0017134 fibroblast growth factor binding 1/139 23/18639 0.0434782608695652 5.8301532686894 0.158245525178617 0.385586702356094 GO:0031681 G-protein beta-subunit binding 1/139 23/18639 0.0434782608695652 5.8301532686894 0.158245525178617 0.385586702356094 GO:0099186 structural constituent of postsynapse 1/139 23/18639 0.0434782608695652 5.8301532686894 0.158245525178617 0.385586702356094 GO:0008237 metallopeptidase activity 3/139 184/18639 0.016304347826087 2.18630747575852 0.158498380055029 0.385586702356094 GO:0015149 hexose transmembrane transporter activity 1/139 24/18639 0.0416666666666667 5.58723021582734 0.164530649372868 0.388196604938508 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/139 24/18639 0.0416666666666667 5.58723021582734 0.164530649372868 0.388196604938508 GO:0019957 C-C chemokine binding 1/139 24/18639 0.0416666666666667 5.58723021582734 0.164530649372868 0.388196604938508 GO:0055056 D-glucose transmembrane transporter activity 1/139 24/18639 0.0416666666666667 5.58723021582734 0.164530649372868 0.388196604938508 GO:0070840 dynein complex binding 1/139 24/18639 0.0416666666666667 5.58723021582734 0.164530649372868 0.388196604938508 GO:0046943 carboxylic acid transmembrane transporter activity 3/139 188/18639 0.0159574468085106 2.13979029542324 0.165695816139666 0.388196604938508 GO:0005342 organic acid transmembrane transporter activity 3/139 189/18639 0.0158730158730159 2.12846865364851 0.167510319047333 0.388196604938508 GO:0005537 D-mannose binding 1/139 25/18639 0.04 5.36374100719425 0.170769179576315 0.388196604938508 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/139 25/18639 0.04 5.36374100719425 0.170769179576315 0.388196604938508 GO:0019211 phosphatase activator activity 1/139 25/18639 0.04 5.36374100719425 0.170769179576315 0.388196604938508 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/139 25/18639 0.04 5.36374100719425 0.170769179576315 0.388196604938508 GO:0019707 protein-cysteine S-acyltransferase activity 1/139 25/18639 0.04 5.36374100719425 0.170769179576315 0.388196604938508 GO:0005112 Notch binding 1/139 26/18639 0.0384615384615385 5.15744327614831 0.176961458723134 0.393668271811891 GO:0015145 monosaccharide transmembrane transporter activity 1/139 26/18639 0.0384615384615385 5.15744327614831 0.176961458723134 0.393668271811891 GO:0034237 protein kinase A regulatory subunit binding 1/139 26/18639 0.0384615384615385 5.15744327614831 0.176961458723134 0.393668271811891 GO:0050681 nuclear androgen receptor binding 1/139 26/18639 0.0384615384615385 5.15744327614831 0.176961458723134 0.393668271811891 GO:0008395 steroid hydroxylase activity 1/139 27/18639 0.037037037037037 4.96642685851319 0.183107827241776 0.400909769118835 GO:0015252 proton channel activity 1/139 27/18639 0.037037037037037 4.96642685851319 0.183107827241776 0.400909769118835 GO:0035255 ionotropic glutamate receptor binding 1/139 27/18639 0.037037037037037 4.96642685851319 0.183107827241776 0.400909769118835 GO:0046625 sphingolipid binding 1/139 28/18639 0.0357142857142857 4.78905447070915 0.189208623073142 0.409486778886455 GO:0051119 sugar transmembrane transporter activity 1/139 28/18639 0.0357142857142857 4.78905447070915 0.189208623073142 0.409486778886455 GO:0019888 protein phosphatase regulator activity 2/139 107/18639 0.0186915887850467 2.50642103139918 0.189978241166072 0.409486778886455 GO:0003785 actin monomer binding 1/139 29/18639 0.0344827586206897 4.62391466137435 0.19526418168863 0.410442803043852 GO:0016417 S-acyltransferase activity 1/139 29/18639 0.0344827586206897 4.62391466137435 0.19526418168863 0.410442803043852 GO:0043236 laminin binding 1/139 29/18639 0.0344827586206897 4.62391466137435 0.19526418168863 0.410442803043852 GO:0051861 glycolipid binding 1/139 29/18639 0.0344827586206897 4.62391466137435 0.19526418168863 0.410442803043852 GO:0016887 ATP hydrolysis activity 5/139 417/18639 0.0119904076738609 1.60783603333161 0.201139140747566 0.410442803043852 GO:0001965 G-protein alpha-subunit binding 1/139 30/18639 0.0333333333333333 4.46978417266187 0.201274836108043 0.410442803043852 GO:0001968 fibronectin binding 1/139 30/18639 0.0333333333333333 4.46978417266187 0.201274836108043 0.410442803043852 GO:0016769 transferase activity, transferring nitrogenous groups 1/139 30/18639 0.0333333333333333 4.46978417266187 0.201274836108043 0.410442803043852 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/139 30/18639 0.0333333333333333 4.46978417266187 0.201274836108043 0.410442803043852 GO:0070566 adenylyltransferase activity 1/139 30/18639 0.0333333333333333 4.46978417266187 0.201274836108043 0.410442803043852 GO:0098918 structural constituent of synapse 1/139 30/18639 0.0333333333333333 4.46978417266187 0.201274836108043 0.410442803043852 GO:0051015 actin filament binding 3/139 209/18639 0.0143540669856459 1.92478744277305 0.204925706046599 0.415849237636025 GO:0017147 Wnt-protein binding 1/139 31/18639 0.032258064516129 4.32559758644697 0.207240916917382 0.418505929308887 GO:0001221 transcription coregulator binding 2/139 115/18639 0.0173913043478261 2.33206130747576 0.211682050339108 0.420264004507973 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/139 32/18639 0.03125 4.1904226618705 0.213162752286496 0.420264004507973 GO:0042910 xenobiotic transmembrane transporter activity 1/139 32/18639 0.03125 4.1904226618705 0.213162752286496 0.420264004507973 GO:0043425 bHLH transcription factor binding 1/139 32/18639 0.03125 4.1904226618705 0.213162752286496 0.420264004507973 GO:0140142 nucleocytoplasmic carrier activity 1/139 32/18639 0.03125 4.1904226618705 0.213162752286496 0.420264004507973 GO:0019208 phosphatase regulator activity 2/139 117/18639 0.0170940170940171 2.29219701162147 0.217147983536345 0.423818222708992 GO:0019956 chemokine binding 1/139 33/18639 0.0303030303030303 4.06344015696534 0.219040667986618 0.423818222708992 GO:0071889 14-3-3 protein binding 1/139 33/18639 0.0303030303030303 4.06344015696534 0.219040667986618 0.423818222708992 GO:0140311 protein sequestering activity 1/139 33/18639 0.0303030303030303 4.06344015696534 0.219040667986618 0.423818222708992 GO:0016831 carboxy-lyase activity 1/139 34/18639 0.0294117647058824 3.94392721117224 0.224874987407765 0.429119242025827 GO:0019825 oxygen binding 1/139 34/18639 0.0294117647058824 3.94392721117224 0.224874987407765 0.429119242025827 GO:0090482 vitamin transmembrane transporter activity 1/139 34/18639 0.0294117647058824 3.94392721117224 0.224874987407765 0.429119242025827 GO:0016229 steroid dehydrogenase activity 1/139 35/18639 0.0285714285714286 3.83124357656732 0.230666031576017 0.438160133039375 GO:0003924 GTPase activity 4/139 331/18639 0.0120845921450151 1.62046556108587 0.234232603593881 0.442912559522974 GO:0016409 palmitoyltransferase activity 1/139 36/18639 0.0277777777777778 3.72482014388489 0.23641411917067 0.443010241328823 GO:0045505 dynein intermediate chain binding 1/139 36/18639 0.0277777777777778 3.72482014388489 0.23641411917067 0.443010241328823 GO:0042826 histone deacetylase binding 2/139 127/18639 0.015748031496063 2.11170905795049 0.244637310015883 0.452094728479822 GO:0005085 guanyl-nucleotide exchange factor activity 3/139 230/18639 0.0130434782608696 1.74904598060682 0.246028954827172 0.452094728479822 GO:0000146 microfilament motor activity 1/139 38/18639 0.0263157894736842 3.52877697841727 0.247782687724518 0.452094728479822 GO:0005109 frizzled binding 1/139 38/18639 0.0263157894736842 3.52877697841727 0.247782687724518 0.452094728479822 GO:0005501 retinoid binding 1/139 38/18639 0.0263157894736842 3.52877697841727 0.247782687724518 0.452094728479822 GO:0019840 isoprenoid binding 1/139 38/18639 0.0263157894736842 3.52877697841727 0.247782687724518 0.452094728479822 GO:0015144 carbohydrate transmembrane transporter activity 1/139 40/18639 0.025 3.3523381294964 0.258983196212124 0.466393981057331 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/139 40/18639 0.025 3.3523381294964 0.258983196212124 0.466393981057331 GO:0071855 neuropeptide receptor binding 1/139 40/18639 0.025 3.3523381294964 0.258983196212124 0.466393981057331 GO:0001530 lipopolysaccharide binding 1/139 41/18639 0.024390243902439 3.27057378487454 0.264521200176128 0.472278194305877 GO:0042287 MHC protein binding 1/139 41/18639 0.024390243902439 3.27057378487454 0.264521200176128 0.472278194305877 GO:0140789 histone phosphatase activity 2/139 136/18639 0.0147058823529412 1.97196360558612 0.269496739282926 0.475964128402105 GO:0008307 structural constituent of muscle 1/139 42/18639 0.0238095238095238 3.19270298047276 0.270018111305041 0.475964128402105 GO:0031492 nucleosomal DNA binding 1/139 42/18639 0.0238095238095238 3.19270298047276 0.270018111305041 0.475964128402105 GO:0001046 core promoter sequence-specific DNA binding 1/139 44/18639 0.0227272727272727 3.047580117724 0.2808898637311 0.490967156773688 GO:0001223 transcription coactivator binding 1/139 44/18639 0.0227272727272727 3.047580117724 0.2808898637311 0.490967156773688 GO:0140104 molecular carrier activity 3/139 249/18639 0.0120481927710843 1.61558464072116 0.28423803393131 0.492377333564982 GO:0008009 chemokine activity 1/139 45/18639 0.0222222222222222 2.97985611510791 0.286265303846259 0.492377333564982 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/139 46/18639 0.0217391304347826 2.9150766343447 0.29160084879438 0.492377333564982 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/139 46/18639 0.0217391304347826 2.9150766343447 0.29160084879438 0.492377333564982 GO:0046982 protein heterodimerization activity 4/139 369/18639 0.010840108401084 1.45358834883313 0.296574737619386 0.492377333564982 GO:0043495 protein-membrane adaptor activity 1/139 47/18639 0.0212765957446809 2.85305372723098 0.296896792537595 0.492377333564982 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/139 48/18639 0.0208333333333333 2.79361510791367 0.302153426887706 0.492377333564982 GO:0005004 GPI-linked ephrin receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0005008 hepatocyte growth factor receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0005009 insulin receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0005011 macrophage colony-stimulating factor receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0005020 stem cell factor receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0008288 boss receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0035254 glutamate receptor binding 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0036332 placental growth factor receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0038062 protein tyrosine kinase collagen receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0060175 brain-derived neurotrophic factor receptor activity 1/139 49/18639 0.0204081632653061 2.73660255469094 0.307371041521809 0.492377333564982 GO:0003712 transcription coregulator activity 5/139 495/18639 0.0101010101010101 1.35448005232178 0.310065690760884 0.492377333564982 GO:0005006 epidermal growth factor receptor activity 1/139 50/18639 0.02 2.68187050359712 0.312549923997789 0.492377333564982 GO:0005007 fibroblast growth factor receptor activity 1/139 50/18639 0.02 2.68187050359712 0.312549923997789 0.492377333564982 GO:0005017 platelet-derived growth factor receptor activity 1/139 50/18639 0.02 2.68187050359712 0.312549923997789 0.492377333564982 GO:0005019 platelet-derived growth factor beta-receptor activity 1/139 50/18639 0.02 2.68187050359712 0.312549923997789 0.492377333564982 GO:0048020 CCR chemokine receptor binding 1/139 50/18639 0.02 2.68187050359712 0.312549923997789 0.492377333564982 GO:0005543 phospholipid binding 5/139 497/18639 0.0100603621730382 1.34902942836877 0.312990341251091 0.492377333564982 GO:0005010 insulin-like growth factor receptor activity 1/139 51/18639 0.0196078431372549 2.62928480744816 0.317690359769714 0.492377333564982 GO:0005021 vascular endothelial growth factor receptor activity 1/139 51/18639 0.0196078431372549 2.62928480744816 0.317690359769714 0.492377333564982 GO:0005030 neurotrophin receptor activity 1/139 51/18639 0.0196078431372549 2.62928480744816 0.317690359769714 0.492377333564982 GO:0016830 carbon-carbon lyase activity 1/139 51/18639 0.0196078431372549 2.62928480744816 0.317690359769714 0.492377333564982 GO:0005506 iron ion binding 2/139 154/18639 0.012987012987013 1.74147435298514 0.319081027817032 0.492377333564982 GO:0030159 signaling receptor complex adaptor activity 1/139 52/18639 0.0192307692307692 2.57872163807416 0.322792632203112 0.492377333564982 GO:0140375 immune receptor activity 2/139 156/18639 0.0128205128205128 1.7191477587161 0.32455296073313 0.492377333564982 GO:0004864 protein phosphatase inhibitor activity 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0005003 ephrin receptor activity 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0005005 transmembrane-ephrin receptor activity 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0005544 calcium-dependent phospholipid binding 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0017046 peptide hormone binding 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0038064 collagen receptor activity 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0051018 protein kinase A binding 1/139 53/18639 0.0188679245283019 2.53006651282747 0.327857022590144 0.492377333564982 GO:0015485 cholesterol binding 1/139 54/18639 0.0185185185185185 2.48321342925659 0.332883810164661 0.492810195830957 GO:0050661 NADP binding 1/139 54/18639 0.0185185185185185 2.48321342925659 0.332883810164661 0.492810195830957 GO:0051287 NAD binding 1/139 54/18639 0.0185185185185185 2.48321342925659 0.332883810164661 0.492810195830957 GO:0140463 chromatin-protein adaptor activity 1/139 54/18639 0.0185185185185185 2.48321342925659 0.332883810164661 0.492810195830957 GO:0008017 microtubule binding 3/139 276/18639 0.0108695652173913 1.45753831717235 0.339246095295215 0.500448140577339 GO:0019212 phosphatase inhibitor activity 1/139 56/18639 0.0178571428571429 2.39452723535457 0.342825683609607 0.503941640924369 GO:0016504 peptidase activator activity 1/139 57/18639 0.0175438596491228 2.35251798561151 0.347741317790217 0.509367564087078 GO:0031267 small GTPase binding 3/139 283/18639 0.0106007067137809 1.42148613264865 0.353514215853335 0.515532503453963 GO:0016874 ligase activity 2/139 167/18639 0.0119760479041916 1.60591048119588 0.354428596124599 0.515532503453963 GO:0004879 nuclear receptor activity 1/139 59/18639 0.0169491525423729 2.2727716132179 0.357463336827503 0.516335930973061 GO:0070063 RNA polymerase binding 1/139 59/18639 0.0169491525423729 2.2727716132179 0.357463336827503 0.516335930973061 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/139 60/18639 0.0166666666666667 2.23489208633094 0.362270258042841 0.519670439123524 GO:0098531 ligand-modulated transcription factor activity 1/139 60/18639 0.0166666666666667 2.23489208633094 0.362270258042841 0.519670439123524 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/139 61/18639 0.0163934426229508 2.19825451114518 0.367041474692394 0.524705338391876 GO:0004721 phosphoprotein phosphatase activity 2/139 175/18639 0.0114285714285714 1.53249743062693 0.375869604797556 0.534521446246263 GO:0005507 copper ion binding 1/139 63/18639 0.0158730158730159 2.12846865364851 0.376477845553257 0.534521446246263 GO:0019843 rRNA binding 1/139 65/18639 0.0153846153846154 2.06297731045932 0.385774532736631 0.545857842239586 GO:0016500 protein-hormone receptor activity 1/139 67/18639 0.0149253731343284 2.00139589820681 0.394933589173887 0.556923298631651 GO:0032934 sterol binding 1/139 68/18639 0.0147058823529412 1.97196360558612 0.39946213920107 0.559515992955034 GO:1990841 promoter-specific chromatin binding 1/139 68/18639 0.0147058823529412 1.97196360558612 0.39946213920107 0.559515992955034 GO:0140597 protein carrier chaperone 2/139 188/18639 0.0106382978723404 1.42652686361549 0.410070948616744 0.572448035652905 GO:0042379 chemokine receptor binding 1/139 72/18639 0.0138888888888889 1.86241007194245 0.417242298991756 0.579697656420637 GO:0051020 GTPase binding 3/139 315/18639 0.00952380952380952 1.27708119218911 0.418051194534113 0.579697656420637 GO:0031491 nucleosome binding 1/139 74/18639 0.0135135135135135 1.81207466459265 0.425935386076517 0.588668174776848 GO:0019003 GDP binding 1/139 75/18639 0.0133333333333333 1.78791366906475 0.430233526735573 0.592639560006617 GO:0017022 myosin binding 1/139 76/18639 0.0131578947368421 1.76438848920863 0.434499716122761 0.596540864379764 GO:0030971 receptor tyrosine kinase binding 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0033192 calmodulin-dependent protein phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0140791 histone H2AXS140 phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/139 81/18639 0.0123456790123457 1.6554756195044 0.455359587091912 0.60714611612255 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/139 82/18639 0.0121951219512195 1.63528689243727 0.459438960806441 0.608236615760111 GO:0033549 MAP kinase phosphatase activity 1/139 82/18639 0.0121951219512195 1.63528689243727 0.459438960806441 0.608236615760111 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/139 83/18639 0.0120481927710843 1.61558464072116 0.4634879980672 0.608236615760111 GO:0005254 chloride channel activity 1/139 83/18639 0.0120481927710843 1.61558464072116 0.4634879980672 0.608236615760111 GO:0030165 PDZ domain binding 1/139 83/18639 0.0120481927710843 1.61558464072116 0.4634879980672 0.608236615760111 GO:0017018 myosin phosphatase activity 1/139 84/18639 0.0119047619047619 1.59635149023638 0.467506922849947 0.609664200330966 GO:0051117 ATPase binding 1/139 84/18639 0.0119047619047619 1.59635149023638 0.467506922849947 0.609664200330966 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/139 89/18639 0.0112359550561798 1.50666882224557 0.487157584496458 0.631331947509429 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/139 89/18639 0.0112359550561798 1.50666882224557 0.487157584496458 0.631331947509429 GO:0019210 kinase inhibitor activity 1/139 90/18639 0.0111111111111111 1.48992805755396 0.49100044680131 0.632372092474752 GO:0140793 histone H2AXY142 phosphatase activity 1/139 90/18639 0.0111111111111111 1.48992805755396 0.49100044680131 0.632372092474752 GO:0030695 GTPase regulator activity 4/139 489/18639 0.0081799591002045 1.09687955157347 0.496976748056231 0.63625108863804 GO:0060589 nucleoside-triphosphatase regulator activity 4/139 490/18639 0.00816326530612245 1.09464102187638 0.498575137688227 0.63625108863804 GO:0043178 alcohol binding 1/139 92/18639 0.0108695652173913 1.45753831717235 0.498600612730772 0.63625108863804 GO:0051213 dioxygenase activity 1/139 93/18639 0.010752688172043 1.44186586214899 0.502358337151456 0.639085835642219 GO:0004867 serine-type endopeptidase inhibitor activity 1/139 95/18639 0.0105263157894737 1.41151079136691 0.509790109348951 0.646563065515743 GO:0004725 protein tyrosine phosphatase activity 1/139 98/18639 0.0102040816326531 1.36830127734547 0.520731651787166 0.65843272687982 GO:0004722 protein serine/threonine phosphatase activity 1/139 103/18639 0.00970873786407767 1.30187888524132 0.538431310251617 0.676699169379676 GO:0005253 monoatomic anion channel activity 1/139 103/18639 0.00970873786407767 1.30187888524132 0.538431310251617 0.676699169379676 GO:0004497 monooxygenase activity 1/139 106/18639 0.00943396226415094 1.26503325641374 0.548737990907831 0.685281481081753 GO:0008013 beta-catenin binding 1/139 106/18639 0.00943396226415094 1.26503325641374 0.548737990907831 0.685281481081753 GO:0015631 tubulin binding 3/139 385/18639 0.00779220779220779 1.04488461179109 0.550201958368523 0.685281481081753 GO:0005496 steroid binding 1/139 108/18639 0.00925925925925926 1.2416067146283 0.555481839650324 0.689792374013537 GO:0017124 SH3 domain binding 1/139 115/18639 0.00869565217391304 1.16603065373788 0.578306891784785 0.711762328350505 GO:0035401 histone H3Y41 kinase activity 1/139 115/18639 0.00869565217391304 1.16603065373788 0.578306891784785 0.711762328350505 GO:0140801 histone H2AXY142 kinase activity 1/139 115/18639 0.00869565217391304 1.16603065373788 0.578306891784785 0.711762328350505 GO:1990782 protein tyrosine kinase binding 1/139 117/18639 0.00854700854700855 1.14609850581074 0.584611900866804 0.715366242907093 GO:0004175 endopeptidase activity 3/139 405/18639 0.00740740740740741 0.993285371702638 0.58467433314522 0.715366242907093 GO:0015108 chloride transmembrane transporter activity 1/139 121/18639 0.00826446280991736 1.10821095189964 0.596942492149505 0.727657893383344 GO:0008528 G protein-coupled peptide receptor activity 1/139 122/18639 0.00819672131147541 1.09912725557259 0.599967926515594 0.727657893383344 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/139 122/18639 0.00819672131147541 1.09912725557259 0.599967926515594 0.727657893383344 GO:0016791 phosphatase activity 2/139 273/18639 0.00732600732600733 0.982370147837774 0.606676724210157 0.733655573463445 GO:0001653 peptide receptor activity 1/139 128/18639 0.0078125 1.04760566546763 0.61765283389692 0.740471408936941 GO:0031490 chromatin DNA binding 1/139 128/18639 0.0078125 1.04760566546763 0.61765283389692 0.740471408936941 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/139 128/18639 0.0078125 1.04760566546763 0.61765283389692 0.740471408936941 GO:0035591 signaling adaptor activity 1/139 129/18639 0.00775193798449612 1.03948469131671 0.620523897377462 0.741775693416737 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/139 132/18639 0.00757575757575758 1.01586003924133 0.629009290329545 0.749764655521749 GO:0019207 kinase regulator activity 2/139 287/18639 0.00696864111498258 0.934449652821297 0.633932747080761 0.753474350815991 GO:0016779 nucleotidyltransferase activity 1/139 136/18639 0.00735294117647059 0.98598180279306 0.640030792801817 0.756400027856693 GO:0044325 transmembrane transporter binding 1/139 136/18639 0.00735294117647059 0.98598180279306 0.640030792801817 0.756400027856693 GO:0016922 nuclear receptor binding 1/139 137/18639 0.0072992700729927 0.978784855327417 0.642734987786444 0.757444064926801 GO:0004713 protein tyrosine kinase activity 1/139 140/18639 0.00714285714285714 0.957810894141829 0.650727151153738 0.764696313220212 GO:0019903 protein phosphatase binding 1/139 144/18639 0.00694444444444444 0.931205035971223 0.661107889959221 0.774706710487426 GO:0008509 monoatomic anion transmembrane transporter activity 1/139 149/18639 0.00671140939597315 0.899956544831249 0.67365403580669 0.787191232852762 GO:0003774 cytoskeletal motor activity 1/139 153/18639 0.0065359477124183 0.876428269149386 0.683358032858543 0.796293954255333 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/139 484/18639 0.00619834710743802 0.831158213924728 0.703703065216837 0.817710824386046 GO:0015103 inorganic anion transmembrane transporter activity 1/139 165/18639 0.00606060606060606 0.812688031393067 0.710784163404806 0.823638473471864 GO:0001216 DNA-binding transcription activator activity 3/139 491/18639 0.00610997963340122 0.819308707819895 0.712895190710743 0.823789998154637 GO:0003735 structural constituent of ribosome 1/139 175/18639 0.00571428571428571 0.766248715313464 0.731827773733793 0.843325079981324 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/139 181/18639 0.00552486187845304 0.74084820541357 0.743716721156655 0.85301867340872 GO:0141003 histone H2AX kinase activity 2/139 354/18639 0.00564971751412429 0.7575905377393 0.744340813575397 0.85301867340872 GO:0140996 histone H3 kinase activity 2/139 357/18639 0.00560224089635854 0.751224230699474 0.748549907428988 0.855485608490272 GO:0035173 histone kinase activity 2/139 360/18639 0.00555555555555556 0.744964028776978 0.752699860065355 0.85787162133476 GO:0042578 phosphoric ester hydrolase activity 2/139 363/18639 0.00550964187327824 0.738807301266425 0.756791199924014 0.860177975869917 GO:0019902 phosphatase binding 1/139 190/18639 0.00526315789473684 0.705755395683453 0.760575862503739 0.862124138423857 GO:0005525 GTP binding 2/139 378/18639 0.00529100529100529 0.70948955121617 0.77638758255461 0.877116721637269 GO:0016829 lyase activity 1/139 200/18639 0.005 0.670467625899281 0.778019399721519 0.877116721637269 GO:0005516 calmodulin binding 1/139 207/18639 0.00483091787439614 0.647794807632155 0.78947322310975 0.881730194440858 GO:0019001 guanyl nucleotide binding 2/139 400/18639 0.005 0.670467625899281 0.802646507973905 0.881730194440858 GO:0032561 guanyl ribonucleotide binding 2/139 400/18639 0.005 0.670467625899281 0.802646507973905 0.881730194440858 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/139 229/18639 0.00436681222707424 0.585561245326883 0.821786602492549 0.881730194440858 GO:0000287 magnesium ion binding 1/139 230/18639 0.00434782608695652 0.58301532686894 0.823132157204854 0.881730194440858 GO:0004674 protein serine/threonine kinase activity 2/139 433/18639 0.0046189376443418 0.619369631315733 0.836943336253321 0.881730194440858 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/139 243/18639 0.00411522633744856 0.551825206501465 0.839733254534091 0.881730194440858 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0004711 ribosomal protein S6 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0035175 histone H3S10 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0035979 histone H2AXS139 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0044022 histone H3S28 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0044023 histone H4S1 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0044024 histone H2AS1 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0044025 histone H2BS14 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0072354 histone H3T3 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0072371 histone H2AS121 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0140823 histone H2BS36 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0140855 histone H3S57 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0140995 histone H2A kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0140997 histone H4 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0140998 histone H2B kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:1990244 histone H2AT120 kinase activity 1/139 245/18639 0.00408163265306122 0.547320510938188 0.842146117751279 0.881730194440858 GO:0004677 DNA-dependent protein kinase activity 1/139 246/18639 0.0040650406504065 0.545095630812423 0.84333898986352 0.881730194440858 GO:0140857 histone H3T45 kinase activity 1/139 246/18639 0.0040650406504065 0.545095630812423 0.84333898986352 0.881730194440858 GO:0035402 histone H3T11 kinase activity 1/139 247/18639 0.00404858299595142 0.542888765910349 0.844522912030049 0.881730194440858 GO:0035403 histone H3T6 kinase activity 1/139 247/18639 0.00404858299595142 0.542888765910349 0.844522912030049 0.881730194440858 GO:0042393 histone binding 1/139 247/18639 0.00404858299595142 0.542888765910349 0.844522912030049 0.881730194440858 GO:0004679 AMP-activated protein kinase activity 1/139 248/18639 0.00403225806451613 0.540699698305871 0.845697950918035 0.881730194440858 GO:0005216 monoatomic ion channel activity 2/139 448/18639 0.00446428571428571 0.598631808838643 0.850689206948192 0.882360054735427 GO:0004842 ubiquitin-protein transferase activity 2/139 449/18639 0.0044543429844098 0.597298553139671 0.851567330842533 0.882360054735427 GO:0019887 protein kinase regulator activity 1/139 255/18639 0.00392156862745098 0.525856961489632 0.853679988753663 0.882360054735427 GO:0003713 transcription coactivator activity 1/139 256/18639 0.00390625 0.523802832733813 0.854786303024945 0.882360054735427 GO:0003730 mRNA 3'-UTR binding 1/139 262/18639 0.00381679389312977 0.511807348014718 0.861251933452823 0.886833674050431 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/139 268/18639 0.00373134328358209 0.500348974551702 0.867431661283658 0.890991533565436 GO:0005096 GTPase activator activity 1/139 271/18639 0.003690036900369 0.494810056014229 0.870418256738371 0.891857130057051 GO:0019787 ubiquitin-like protein transferase activity 2/139 479/18639 0.00417536534446764 0.55988945795347 0.875829528126747 0.894328341162422 GO:0001217 DNA-binding transcription repressor activity 1/139 278/18639 0.00359712230215827 0.482350809999482 0.877129719216991 0.894328341162422 GO:0035091 phosphatidylinositol binding 1/139 284/18639 0.00352112676056338 0.472160299929071 0.882606942508521 0.897712684800843 GO:0015291 secondary active transmembrane transporter activity 1/139 287/18639 0.00348432055749129 0.467224826410648 0.885253946259986 0.898208882058912 GO:0016755 aminoacyltransferase activity 2/139 496/18639 0.00403225806451613 0.540699698305871 0.887913414432549 0.898715280788176 GO:0005261 monoatomic cation channel activity 1/139 341/18639 0.00293255131964809 0.393236144222452 0.923936640203726 0.932906898846481 GO:0061630 ubiquitin protein ligase activity 1/139 353/18639 0.0028328611898017 0.379868343285711 0.930589819563193 0.937349551908688 GO:0106310 protein serine kinase activity 1/139 361/18639 0.00277008310249307 0.371450208254449 0.934700919081478 0.939216382458683 GO:0061659 ubiquitin-like protein ligase activity 1/139 372/18639 0.00268817204301075 0.360466465537248 0.939961698637015 0.942226666585538 GO:0046873 metal ion transmembrane transporter activity 1/139 450/18639 0.00222222222222222 0.297985611510791 0.966953370740208 0.966953370740208