ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 14/94 168/18639 0.0833333333333333 16.5239361702128 1.26079331258251e-13 3.30327847896617e-11 GO:0008083 growth factor activity 12/94 162/18639 0.0740740740740741 14.6879432624113 3.18150886016149e-11 4.16777660681156e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/94 68/18639 0.132352941176471 26.2438986232791 5.50587461000099e-11 4.80846382606753e-09 GO:0009055 electron transfer activity 10/94 116/18639 0.0862068965517241 17.0937270726339 3.42865804144355e-10 2.24577101714552e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 9/94 118/18639 0.076271186440678 15.1236025964659 8.13091651817258e-09 4.26060025552243e-07 GO:0015399 primary active transmembrane transporter activity 10/94 166/18639 0.0602409638554217 11.945014098949 1.13633302002711e-08 4.96198752078506e-07 GO:0015078 proton transmembrane transporter activity 10/94 185/18639 0.0540540540540541 10.718228867165 3.19685886001229e-08 1.19653860189031e-06 GO:0005131 growth hormone receptor binding 4/94 10/18639 0.4 79.3148936170213 1.24458413197654e-07 4.07601303222317e-06 GO:0051427 hormone receptor binding 5/94 34/18639 0.147058823529412 29.159887359199 7.26218458035835e-07 2.1141026222821e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 5/94 41/18639 0.121951219512195 24.1813700051894 1.90212194291585e-06 4.98355949043953e-05 GO:0003954 NADH dehydrogenase activity 5/94 44/18639 0.113636363636364 22.5326402321083 2.72380701372281e-06 6.48761306904887e-05 GO:0005179 hormone activity 7/94 132/18639 0.053030303030303 10.5152321083172 4.6713055198905e-06 0.000101990170517609 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/94 58/18639 0.0862068965517241 17.0937270726339 1.08702467384441e-05 0.000219077280420951 GO:0022804 active transmembrane transporter activity 11/94 457/18639 0.0240700218818381 4.7727780622934 1.88914979861846e-05 0.000347661316262983 GO:0048407 platelet-derived growth factor binding 3/94 11/18639 0.272727272727273 54.07833655706 1.99042738318502e-05 0.000347661316262983 GO:0004857 enzyme inhibitor activity 10/94 416/18639 0.0240384615384615 4.76652004909984 4.68509236759114e-05 0.000767183875193049 GO:0004129 cytochrome-c oxidase activity 3/94 15/18639 0.2 39.6574468085106 5.40894334408624e-05 0.000833613621265056 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/94 16/18639 0.1875 37.1788563829787 6.63284028891259e-05 0.000965446753163943 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/94 88/18639 0.0568181818181818 11.2663201160542 8.25056483577044e-05 0.00113770946682729 GO:0050840 extracellular matrix binding 4/94 67/18639 0.0597014925373134 11.838043823436 0.000364643593731947 0.00477683107788851 GO:0002020 protease binding 5/94 136/18639 0.0367647058823529 7.28997183979975 0.00062692077244055 0.00782158297044877 GO:0046332 SMAD binding 4/94 79/18639 0.0506329113924051 10.0398599515217 0.00068261781985423 0.00812935767280947 GO:0005178 integrin binding 5/94 161/18639 0.031055900621118 6.1579886348619 0.00133624108088363 0.0148429340727354 GO:0005539 glycosaminoglycan binding 6/94 242/18639 0.0247933884297521 4.91621241427818 0.00141496666065955 0.0148429340727354 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/94 44/18639 0.0681818181818182 13.519584139265 0.00141631050312361 0.0148429340727354 GO:0004859 phospholipase inhibitor activity 2/94 12/18639 0.166666666666667 33.0478723404255 0.00160709282252007 0.0160599090448518 GO:0030414 peptidase inhibitor activity 5/94 169/18639 0.029585798816568 5.86648621427672 0.00165502879469847 0.0160599090448518 GO:0008201 heparin binding 5/94 172/18639 0.0290697674418605 5.76416378030678 0.00178789306042322 0.0167295707796744 GO:0003735 structural constituent of ribosome 5/94 175/18639 0.0285714285714286 5.66534954407295 0.00192842354482909 0.0174223092670766 GO:0004222 metalloendopeptidase activity 4/94 110/18639 0.0363636363636364 7.21044487427466 0.00232940926220121 0.0203435075565572 GO:0055102 lipase inhibitor activity 2/94 16/18639 0.125 24.7859042553191 0.00288387600307811 0.0243734036389182 GO:0098641 cadherin binding involved in cell-cell adhesion 2/94 18/18639 0.111111111111111 22.031914893617 0.00365291162685111 0.0299082139448434 GO:0019838 growth factor binding 4/94 136/18639 0.0294117647058824 5.8319774718398 0.00498190827210767 0.0395533323421881 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/94 22/18639 0.0909090909090909 18.0261121856867 0.0054434095854637 0.0419462738644556 GO:0061134 peptidase regulator activity 5/94 226/18639 0.0221238938053097 4.38688570890604 0.00574499883581581 0.0430054198566783 GO:0005125 cytokine activity 5/94 234/18639 0.0213675213675214 4.23690671031097 0.00663577705493694 0.0474033227077926 GO:0098631 cell adhesion mediator activity 3/94 76/18639 0.0394736842105263 7.82712765957447 0.00669436236713101 0.0474033227077926 GO:0004866 endopeptidase inhibitor activity 4/94 161/18639 0.0248447204968944 4.92639090788952 0.00896025230013648 0.0617785816483094 GO:0043236 laminin binding 2/94 29/18639 0.0689655172413793 13.6749816581071 0.00935084350328609 0.0628184871246399 GO:0004867 serine-type endopeptidase inhibitor activity 3/94 95/18639 0.0315789473684211 6.26170212765958 0.0123080776326035 0.0806179084935528 GO:1901681 sulfur compound binding 5/94 275/18639 0.0181818181818182 3.60522243713733 0.0127568500585411 0.0815193833009215 GO:0005154 epidermal growth factor receptor binding 2/94 35/18639 0.0571428571428571 11.3306990881459 0.0134384120355478 0.0838253124297111 GO:0008237 metallopeptidase activity 4/94 184/18639 0.0217391304347826 4.31059204440333 0.0140775333851423 0.0838253124297111 GO:0061135 endopeptidase regulator activity 4/94 184/18639 0.0217391304347826 4.31059204440333 0.0140775333851423 0.0838253124297111 GO:0043394 proteoglycan binding 2/94 37/18639 0.0540540540540541 10.718228867165 0.0149443955782255 0.0870095920332239 GO:0071855 neuropeptide receptor binding 2/94 40/18639 0.05 9.91436170212766 0.0173325542919169 0.0987202005322226 GO:0031625 ubiquitin protein ligase binding 5/94 302/18639 0.0165562913907285 3.28290122587009 0.0184040899817541 0.102593012238715 GO:0044389 ubiquitin-like protein ligase binding 5/94 322/18639 0.015527950310559 3.07899431743095 0.0235152593182368 0.128354123778709 GO:0005006 epidermal growth factor receptor activity 2/94 50/18639 0.04 7.93148936170213 0.0263523592510103 0.140904451505402 GO:0045296 cadherin binding 5/94 334/18639 0.0149700598802395 2.96837176710409 0.0269837024769076 0.141394600978996 GO:0005544 calcium-dependent phospholipid binding 2/94 53/18639 0.0377358490566038 7.48253713368125 0.029357435044152 0.150816627089565 GO:0051087 protein-folding chaperone binding 3/94 134/18639 0.0223880597014925 4.4392664337885 0.0303205036087294 0.152768691259367 GO:0098632 cell-cell adhesion mediator activity 2/94 55/18639 0.0363636363636364 7.21044487427466 0.031433189821992 0.154088089448119 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5/94 349/18639 0.0143266475644699 2.84079131866122 0.0317586138557193 0.154088089448119 GO:0001786 phosphatidylserine binding 2/94 59/18639 0.0338983050847458 6.72160115398485 0.0357523794203108 0.169697136614535 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/94 60/18639 0.0333333333333333 6.60957446808511 0.03686615500536 0.169697136614535 GO:0140297 DNA-binding transcription factor binding 6/94 488/18639 0.0122950819672131 2.43795779560516 0.036918842698582 0.169697136614535 GO:0019843 rRNA binding 2/94 65/18639 0.0307692307692308 6.10114566284779 0.0426309036469065 0.192574081991198 GO:1990841 promoter-specific chromatin binding 2/94 68/18639 0.0294117647058824 5.8319774718398 0.0462408348090843 0.205340656270849 GO:0097110 scaffold protein binding 2/94 70/18639 0.0285714285714286 5.66534954407295 0.0487078624469681 0.208392544167422 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.208392544167422 GO:0015203 polyamine transmembrane transporter activity 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.208392544167422 GO:0005126 cytokine receptor binding 4/94 275/18639 0.0145454545454545 2.88417794970986 0.0504724428896715 0.209011171893834 GO:0005518 collagen binding 2/94 72/18639 0.0277777777777778 5.50797872340426 0.0512218242127916 0.209011171893834 GO:0019215 intermediate filament binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.209011171893834 GO:0042608 T cell receptor binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.209011171893834 GO:1990948 ubiquitin ligase inhibitor activity 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.209011171893834 GO:0044183 protein folding chaperone 2/94 75/18639 0.0266666666666667 5.28765957446809 0.0550782104755932 0.209011171893834 GO:0005049 nuclear export signal receptor activity 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.209011171893834 GO:0005095 GTPase inhibitor activity 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.209011171893834 GO:0008504 monoamine transmembrane transporter activity 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.209011171893834 GO:0008603 cAMP-dependent protein kinase regulator activity 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.209011171893834 GO:0070410 co-SMAD binding 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.209011171893834 GO:0019199 transmembrane receptor protein kinase activity 2/94 78/18639 0.0256410256410256 5.08428805237316 0.0590336897715409 0.209011171893834 GO:0048306 calcium-dependent protein binding 2/94 80/18639 0.025 4.95718085106383 0.0617238544544612 0.211038417299612 GO:0001664 G protein-coupled receptor binding 4/94 297/18639 0.0134680134680135 2.67053513862025 0.0633797837667477 0.211038417299612 GO:0004465 lipoprotein lipase activity 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.211038417299612 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.211038417299612 GO:0070700 BMP receptor binding 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.211038417299612 GO:0008191 metalloendopeptidase inhibitor activity 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.21578474447709 GO:0008559 ABC-type xenobiotic transporter activity 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.21578474447709 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.21578474447709 GO:0034236 protein kinase A catalytic subunit binding 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.21578474447709 GO:0031386 protein tag activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.220023568181509 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.220023568181509 GO:0140776 protein-containing complex destabilizing activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.220023568181509 GO:0141047 molecular tag activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.220023568181509 GO:0072341 modified amino acid binding 2/94 91/18639 0.021978021978022 4.35796118774842 0.0772286216126136 0.228851858723487 GO:0005521 lamin binding 1/94 16/18639 0.0625 12.3929521276596 0.0777397535358408 0.228851858723487 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.229653820907564 GO:0019198 transmembrane receptor protein phosphatase activity 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.229653820907564 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.229653820907564 GO:0030548 acetylcholine receptor regulator activity 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.229653820907564 GO:0048038 quinone binding 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.229653820907564 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/94 18/18639 0.0555555555555556 11.0159574468085 0.0870267629387879 0.237510540520442 GO:0099602 neurotransmitter receptor regulator activity 1/94 18/18639 0.0555555555555556 11.0159574468085 0.0870267629387879 0.237510540520442 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.244984731571078 GO:0043395 heparan sulfate proteoglycan binding 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.244984731571078 GO:0005326 neurotransmitter transmembrane transporter activity 1/94 20/18639 0.05 9.91436170212766 0.0962212386407146 0.2496036091472 GO:0043024 ribosomal small subunit binding 1/94 20/18639 0.05 9.91436170212766 0.0962212386407146 0.2496036091472 GO:0140939 histone H4 methyltransferase activity 1/94 20/18639 0.05 9.91436170212766 0.0962212386407146 0.2496036091472 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/94 484/18639 0.0103305785123967 2.04842183928257 0.0978982397765893 0.251464106092808 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/94 21/18639 0.0476190476190476 9.44224924012158 0.100784061755156 0.251480230284293 GO:0001846 opsonin binding 1/94 21/18639 0.0476190476190476 9.44224924012158 0.100784061755156 0.251480230284293 GO:0051428 peptide hormone receptor binding 1/94 21/18639 0.0476190476190476 9.44224924012158 0.100784061755156 0.251480230284293 GO:0001216 DNA-binding transcription activator activity 5/94 491/18639 0.010183299389002 2.01921826927244 0.102457634756797 0.253244342512082 GO:0004620 phospholipase activity 2/94 109/18639 0.018348623853211 3.63829787234043 0.104846650994741 0.255508447374482 GO:0008970 phospholipase A1 activity 1/94 22/18639 0.0454545454545455 9.01305609284333 0.105324092810855 0.255508447374482 GO:0005212 structural constituent of eye lens 1/94 23/18639 0.0434782608695652 8.62118408880666 0.109841444439784 0.264022554524986 GO:0004806 triacylglycerol lipase activity 1/94 24/18639 0.0416666666666667 8.26196808510638 0.11433622872334 0.265098158632876 GO:0030552 cAMP binding 1/94 24/18639 0.0416666666666667 8.26196808510638 0.11433622872334 0.265098158632876 GO:0035035 histone acetyltransferase binding 1/94 24/18639 0.0416666666666667 8.26196808510638 0.11433622872334 0.265098158632876 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/94 24/18639 0.0416666666666667 8.26196808510638 0.11433622872334 0.265098158632876 GO:0001848 complement binding 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.270676886826876 GO:0120020 cholesterol transfer activity 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.270676886826876 GO:0050681 nuclear androgen receptor binding 1/94 26/18639 0.0384615384615385 7.62643207855974 0.123258540842992 0.271982178939668 GO:0050750 low-density lipoprotein particle receptor binding 1/94 26/18639 0.0384615384615385 7.62643207855974 0.123258540842992 0.271982178939668 GO:0070412 R-SMAD binding 1/94 26/18639 0.0384615384615385 7.62643207855974 0.123258540842992 0.271982178939668 GO:0051082 unfolded protein binding 2/94 121/18639 0.0165289256198347 3.27747494285212 0.124522904266368 0.271982178939668 GO:0008395 steroid hydroxylase activity 1/94 27/18639 0.037037037037037 7.34397163120567 0.127686290112898 0.271982178939668 GO:0015252 proton channel activity 1/94 27/18639 0.037037037037037 7.34397163120567 0.127686290112898 0.271982178939668 GO:0023026 MHC class II protein complex binding 1/94 27/18639 0.037037037037037 7.34397163120567 0.127686290112898 0.271982178939668 GO:0035255 ionotropic glutamate receptor binding 1/94 27/18639 0.037037037037037 7.34397163120567 0.127686290112898 0.271982178939668 GO:0042277 peptide binding 3/94 249/18639 0.0120481927710843 2.3890028197898 0.131259013254334 0.277337592521255 GO:0016298 lipase activity 2/94 130/18639 0.0153846153846154 3.0505728314239 0.139815431277912 0.279769866913639 GO:0001968 fibronectin binding 1/94 30/18639 0.0333333333333333 6.60957446808511 0.140837228025623 0.279769866913639 GO:0033612 receptor serine/threonine kinase binding 1/94 30/18639 0.0333333333333333 6.60957446808511 0.140837228025623 0.279769866913639 GO:0005184 neuropeptide hormone activity 1/94 31/18639 0.032258064516129 6.39636238846946 0.145177133478123 0.279769866913639 GO:0017147 Wnt-protein binding 1/94 31/18639 0.032258064516129 6.39636238846946 0.145177133478123 0.279769866913639 GO:0047499 calcium-independent phospholipase A2 activity 1/94 31/18639 0.032258064516129 6.39636238846946 0.145177133478123 0.279769866913639 GO:0070325 lipoprotein particle receptor binding 1/94 31/18639 0.032258064516129 6.39636238846946 0.145177133478123 0.279769866913639 GO:0004175 endopeptidase activity 4/94 405/18639 0.00987654320987654 1.95839243498818 0.148211364911133 0.279769866913639 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0042910 xenobiotic transmembrane transporter activity 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0047498 calcium-dependent phospholipase A2 activity 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0071813 lipoprotein particle binding 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0071814 protein-lipid complex binding 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0120015 sterol transfer activity 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0140142 nucleocytoplasmic carrier activity 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0160041 neuropeptide activity 1/94 32/18639 0.03125 6.19647606382979 0.149495348732479 0.279769866913639 GO:0019956 chemokine binding 1/94 33/18639 0.0303030303030303 6.00870406189555 0.153791981033181 0.283757035427418 GO:0030296 protein tyrosine kinase activator activity 1/94 33/18639 0.0303030303030303 6.00870406189555 0.153791981033181 0.283757035427418 GO:0070851 growth factor receptor binding 2/94 139/18639 0.0143884892086331 2.85305372723098 0.155490345366536 0.284884408993233 GO:0004713 protein tyrosine kinase activity 2/94 140/18639 0.0142857142857143 2.83267477203647 0.157252809757227 0.285610964967249 GO:0019825 oxygen binding 1/94 34/18639 0.0294117647058824 5.8319774718398 0.158067137100195 0.285610964967249 GO:0020037 heme binding 2/94 142/18639 0.0140845070422535 2.79277794426131 0.160789210300315 0.287351904462536 GO:0004623 phospholipase A2 activity 1/94 35/18639 0.0285714285714286 5.66534954407295 0.162320923131509 0.287351904462536 GO:0016229 steroid dehydrogenase activity 1/94 35/18639 0.0285714285714286 5.66534954407295 0.162320923131509 0.287351904462536 GO:0019955 cytokine binding 2/94 144/18639 0.0138888888888889 2.75398936170213 0.164340360920734 0.28897432591431 GO:0055106 ubiquitin-protein transferase regulator activity 1/94 36/18639 0.0277777777777778 5.50797872340426 0.166553444805646 0.290913350260528 GO:0023023 MHC protein complex binding 1/94 37/18639 0.027027027027027 5.35911443358252 0.170764807284185 0.294344602029319 GO:0030551 cyclic nucleotide binding 1/94 37/18639 0.027027027027027 5.35911443358252 0.170764807284185 0.294344602029319 GO:0005109 frizzled binding 1/94 38/18639 0.0263157894736842 5.21808510638298 0.174955115214261 0.299596341085859 GO:0046906 tetrapyrrole binding 2/94 152/18639 0.0131578947368421 2.60904255319149 0.178679735952235 0.303987602723933 GO:0005506 iron ion binding 2/94 154/18639 0.012987012987013 2.57515888366952 0.182295187357799 0.307804626067878 GO:0140662 ATP-dependent protein folding chaperone 1/94 40/18639 0.025 4.95718085106383 0.183272983460263 0.307804626067878 GO:0042056 chemoattractant activity 1/94 42/18639 0.0238095238095238 4.72112462006079 0.191507876526116 0.319586392674156 GO:0048156 tau protein binding 1/94 43/18639 0.0232558139534884 4.61133102424542 0.195594463588898 0.324340186457539 GO:0001046 core promoter sequence-specific DNA binding 1/94 44/18639 0.0227272727272727 4.50652804642166 0.199660613321241 0.325796066260588 GO:0030547 signaling receptor inhibitor activity 1/94 44/18639 0.0227272727272727 4.50652804642166 0.199660613321241 0.325796066260588 GO:0042605 peptide antigen binding 1/94 45/18639 0.0222222222222222 4.4063829787234 0.203706426838197 0.325796066260588 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/94 46/18639 0.0217391304347826 4.31059204440333 0.207732004759957 0.325796066260588 GO:0030291 protein serine/threonine kinase inhibitor activity 1/94 46/18639 0.0217391304347826 4.31059204440333 0.207732004759957 0.325796066260588 GO:0140359 ABC-type transporter activity 1/94 47/18639 0.0212765957446809 4.21887732005432 0.211737447214244 0.325796066260588 GO:0005004 GPI-linked ephrin receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0005008 hepatocyte growth factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0005009 insulin receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0005011 macrophage colony-stimulating factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0005020 stem cell factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0008288 boss receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0035254 glutamate receptor binding 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0036332 placental growth factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0038062 protein tyrosine kinase collagen receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0060175 brain-derived neurotrophic factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.325796066260588 GO:0005007 fibroblast growth factor receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.325796066260588 GO:0005017 platelet-derived growth factor receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.325796066260588 GO:0005019 platelet-derived growth factor beta-receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.325796066260588 GO:0005319 lipid transporter activity 2/94 178/18639 0.0112359550561798 2.22794644991633 0.226383621862418 0.325796066260588 GO:0003743 translation initiation factor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.325796066260588 GO:0005010 insulin-like growth factor receptor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.325796066260588 GO:0005021 vascular endothelial growth factor receptor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.325796066260588 GO:0005030 neurotrophin receptor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.325796066260588 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/94 181/18639 0.0110497237569061 2.1910191606912 0.231960280637624 0.327991672019381 GO:0005003 ephrin receptor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.327991672019381 GO:0005005 transmembrane-ephrin receptor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.327991672019381 GO:0038064 collagen receptor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.327991672019381 GO:0051018 protein kinase A binding 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.327991672019381 GO:0140463 chromatin-protein adaptor activity 1/94 54/18639 0.0185185185185185 3.67198581560284 0.239220059711834 0.331617225632278 GO:0005543 phospholipid binding 4/94 497/18639 0.00804828973843058 1.59587311100646 0.242069250104982 0.333423072010294 GO:0140313 molecular sequestering activity 1/94 55/18639 0.0181818181818182 3.60522243713733 0.243067964709794 0.333423072010294 GO:0015026 coreceptor activity 1/94 61/18639 0.0163934426229508 3.25061039414022 0.265754337158727 0.362643939247846 GO:0005507 copper ion binding 1/94 63/18639 0.0158730158730159 3.14741641337386 0.273165934849185 0.370826294976614 GO:0038024 cargo receptor activity 1/94 65/18639 0.0153846153846154 3.0505728314239 0.280503506579581 0.376881634481283 GO:0120013 lipid transfer activity 1/94 65/18639 0.0153846153846154 3.0505728314239 0.280503506579581 0.376881634481283 GO:0016500 protein-hormone receptor activity 1/94 67/18639 0.0149253731343284 2.959510955859 0.287767783838935 0.382716545004066 GO:0042054 histone methyltransferase activity 1/94 67/18639 0.0149253731343284 2.959510955859 0.287767783838935 0.382716545004066 GO:0016279 protein-lysine N-methyltransferase activity 1/94 69/18639 0.0144927536231884 2.87372802960222 0.294959490965844 0.390299932490157 GO:0016278 lysine N-methyltransferase activity 1/94 70/18639 0.0142857142857143 2.83267477203647 0.298528355147277 0.393037331902446 GO:0003725 double-stranded RNA binding 1/94 75/18639 0.0133333333333333 2.64382978723404 0.316106329128744 0.414099291158655 GO:0000287 magnesium ion binding 2/94 230/18639 0.00869565217391304 1.72423681776133 0.323339874501197 0.421467896115988 GO:0001618 virus receptor activity 1/94 81/18639 0.0123456790123457 2.44799054373522 0.336625440238098 0.434462390849171 GO:0015101 organic cation transmembrane transporter activity 1/94 81/18639 0.0123456790123457 2.44799054373522 0.336625440238098 0.434462390849171 GO:0140272 exogenous protein binding 1/94 82/18639 0.0121951219512195 2.41813700051894 0.339985565715931 0.436648128517519 GO:0001540 amyloid-beta binding 1/94 83/18639 0.0120481927710843 2.3890028197898 0.343328851636214 0.436652451683117 GO:0008135 translation factor activity, RNA binding 1/94 83/18639 0.0120481927710843 2.3890028197898 0.343328851636214 0.436652451683117 GO:0004860 protein kinase inhibitor activity 1/94 84/18639 0.0119047619047619 2.36056231003039 0.346655381488887 0.436652451683117 GO:0180051 translation factor activity 1/94 84/18639 0.0119047619047619 2.36056231003039 0.346655381488887 0.436652451683117 GO:0016209 antioxidant activity 1/94 86/18639 0.0116279069767442 2.30566551212271 0.353258504905825 0.442840805192948 GO:0140104 molecular carrier activity 2/94 249/18639 0.00803212851405622 1.59266854652653 0.358257018469691 0.446968280185995 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/94 89/18639 0.0112359550561798 2.22794644991633 0.363039583334483 0.448420721995507 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/94 89/18639 0.0112359550561798 2.22794644991633 0.363039583334483 0.448420721995507 GO:0019210 kinase inhibitor activity 1/94 90/18639 0.0111111111111111 2.2031914893617 0.366267307278773 0.448420721995507 GO:0140793 histone H2AXY142 phosphatase activity 1/94 90/18639 0.0111111111111111 2.2031914893617 0.366267307278773 0.448420721995507 GO:0019887 protein kinase regulator activity 2/94 255/18639 0.00784313725490196 1.55519399249061 0.369157780430616 0.44985738824568 GO:0042562 hormone binding 1/94 94/18639 0.0106382978723404 2.10943866002716 0.379017173857401 0.459733794215922 GO:0008276 protein methyltransferase activity 1/94 95/18639 0.0105263157894737 2.08723404255319 0.382164781603824 0.461415542765907 GO:0004725 protein tyrosine phosphatase activity 1/94 98/18639 0.0102040816326531 2.0233391228832 0.391513204344328 0.466256634264609 GO:0008170 N-methyltransferase activity 1/94 98/18639 0.0102040816326531 2.0233391228832 0.391513204344328 0.466256634264609 GO:0042626 ATPase-coupled transmembrane transporter activity 1/94 98/18639 0.0102040816326531 2.0233391228832 0.391513204344328 0.466256634264609 GO:0016791 phosphatase activity 2/94 273/18639 0.00732600732600733 1.45265372924947 0.401413228786955 0.475883556299467 GO:0004497 monooxygenase activity 1/94 106/18639 0.00943396226415094 1.87063428342031 0.415763660931417 0.490676032270412 GO:0019207 kinase regulator activity 2/94 287/18639 0.00696864111498258 1.38179257172511 0.425971887501873 0.500469213118793 GO:0005200 structural constituent of cytoskeleton 1/94 112/18639 0.00892857142857143 1.7704217325228 0.433321669889049 0.504579011159693 GO:0043022 ribosome binding 1/94 112/18639 0.00892857142857143 1.7704217325228 0.433321669889049 0.504579011159693 GO:0001221 transcription coregulator binding 1/94 115/18639 0.00869565217391304 1.72423681776133 0.441903869330794 0.505584339583703 GO:0017124 SH3 domain binding 1/94 115/18639 0.00869565217391304 1.72423681776133 0.441903869330794 0.505584339583703 GO:0035401 histone H3Y41 kinase activity 1/94 115/18639 0.00869565217391304 1.72423681776133 0.441903869330794 0.505584339583703 GO:0140801 histone H2AXY142 kinase activity 1/94 115/18639 0.00869565217391304 1.72423681776133 0.441903869330794 0.505584339583703 GO:1990782 protein tyrosine kinase binding 1/94 117/18639 0.00854700854700855 1.69476268412439 0.447553765518622 0.509822115503822 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/94 122/18639 0.00819672131147541 1.62530519707011 0.461432130669246 0.52335592309672 GO:0031072 heat shock protein binding 1/94 131/18639 0.00763358778625954 1.51364300795842 0.485549420859115 0.548335983901242 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/94 132/18639 0.00757575757575758 1.50217601547389 0.488162256089245 0.548920648478035 GO:0044325 transmembrane transporter binding 1/94 136/18639 0.00735294117647059 1.45799436795995 0.498482949884589 0.555755459020266 GO:0140789 histone phosphatase activity 1/94 136/18639 0.00735294117647059 1.45799436795995 0.498482949884589 0.555755459020266 GO:0016922 nuclear receptor binding 1/94 137/18639 0.0072992700729927 1.44735207330331 0.501030785517235 0.556229092396253 GO:0030295 protein kinase activator activity 1/94 139/18639 0.00719424460431655 1.42652686361549 0.506088100503982 0.55947292123225 GO:0019209 kinase activator activity 1/94 148/18639 0.00675675675675676 1.33977860839563 0.52822559486046 0.58149204140101 GO:0042578 phosphoric ester hydrolase activity 2/94 363/18639 0.00550964187327824 1.09249164761737 0.5492343661736 0.602089556223779 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/94 167/18639 0.00598802395209581 1.18734870684164 0.571787415662622 0.621611215367664 GO:0016874 ligase activity 1/94 167/18639 0.00598802395209581 1.18734870684164 0.571787415662622 0.621611215367664 GO:0003823 antigen binding 1/94 174/18639 0.00574712643678161 1.13958180484226 0.586812484063728 0.634962825213869 GO:0004721 phosphoprotein phosphatase activity 1/94 175/18639 0.00571428571428571 1.13306990881459 0.588915902774695 0.634962825213869 GO:0043021 ribonucleoprotein complex binding 1/94 177/18639 0.00564971751412429 1.12026685899748 0.593091009311224 0.636843624752216 GO:0140597 protein carrier chaperone 1/94 188/18639 0.00531914893617021 1.05471933001358 0.615315199484405 0.658010539856792 GO:0016887 ATP hydrolysis activity 2/94 417/18639 0.00479616306954436 0.951017909076994 0.625070540050328 0.665725534525146 GO:0008168 methyltransferase activity 1/94 204/18639 0.00490196078431373 0.971996245306633 0.645513793882702 0.684715036426186 GO:0003779 actin binding 2/94 443/18639 0.00451467268623025 0.89520195956006 0.65796140244835 0.695104384844628 GO:0016741 transferase activity, transferring one-carbon groups 1/94 215/18639 0.00465116279069767 0.922266204849085 0.664902447778472 0.699616230192609 GO:0005085 guanyl-nucleotide exchange factor activity 1/94 230/18639 0.00434782608695652 0.862118408880666 0.689660785791364 0.72276450350935 GO:0030695 GTPase regulator activity 2/94 489/18639 0.00408997955010225 0.810990732280381 0.710522293071828 0.738074461112524 GO:0060589 nucleoside-triphosphatase regulator activity 2/94 490/18639 0.00408163265306122 0.809335649153278 0.711587225704061 0.738074461112524 GO:0033218 amide binding 1/94 247/18639 0.00404858299595142 0.80278232405892 0.715537836345729 0.738074461112524 GO:0042393 histone binding 1/94 247/18639 0.00404858299595142 0.80278232405892 0.715537836345729 0.738074461112524 GO:0008514 organic anion transmembrane transporter activity 1/94 269/18639 0.00371747211895911 0.737127264098711 0.745879854377605 0.76635498763503 GO:0030246 carbohydrate binding 1/94 280/18639 0.00357142857142857 0.708168693009118 0.759826919182057 0.777635362600386 GO:0005261 monoatomic cation channel activity 1/94 341/18639 0.00293255131964809 0.58148748986086 0.824486314816718 0.840526904599145 GO:0141003 histone H2AX kinase activity 1/94 354/18639 0.00282485875706215 0.560133429498738 0.835856735074778 0.847323897190339 GO:0140996 histone H3 kinase activity 1/94 357/18639 0.00280112044817927 0.555426425889505 0.83837537623626 0.847323897190339 GO:0035173 histone kinase activity 1/94 360/18639 0.00277777777777778 0.550797872340426 0.840855775837741 0.847323897190339 GO:0046982 protein heterodimerization activity 1/94 369/18639 0.002710027100271 0.537363777893098 0.848073227595768 0.851322550306863 GO:0005216 monoatomic ion channel activity 1/94 448/18639 0.00223214285714286 0.442605433130699 0.899010545719338 0.899010545719338