ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 70/755 334/18639 0.209580838323353 5.17400959670064 1.19055708207382e-30 1.10364641508243e-27 GO:0003735 structural constituent of ribosome 45/755 175/18639 0.257142857142857 6.34819299905393 6.15335498432304e-24 2.85208003523373e-21 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 21/755 68/18639 0.308823529411765 7.62405531749124 1.35550402432483e-13 4.18850743516373e-11 GO:0022853 active monoatomic ion transmembrane transporter activity 25/755 118/18639 0.211864406779661 5.23038500392861 7.68710553099609e-12 1.78148670680834e-09 GO:0015078 proton transmembrane transporter activity 29/755 185/18639 0.156756756756757 3.86991945587972 3.81669368327058e-10 7.07615008878365e-08 GO:0043236 laminin binding 12/755 29/18639 0.413793103448276 10.2154829869833 4.9231803683473e-10 7.60631366909659e-08 GO:0015399 primary active transmembrane transporter activity 27/755 166/18639 0.162650602409639 4.01542328253411 6.62853707235216e-10 7.8522736542183e-08 GO:0004857 enzyme inhibitor activity 46/755 416/18639 0.110576923076923 2.72985863474274 6.77650369296078e-10 7.8522736542183e-08 GO:0009055 electron transfer activity 22/755 116/18639 0.189655172413793 4.68209636903403 1.30424633039561e-09 1.34337372030748e-07 GO:0031625 ubiquitin protein ligase binding 37/755 302/18639 0.122516556291391 3.02461734134468 2.02810993607821e-09 1.8800579107445e-07 GO:0005518 collagen binding 17/755 72/18639 0.236111111111111 5.82897350993377 2.98743580240877e-09 2.51759362621176e-07 GO:0044389 ubiquitin-like protein ligase binding 38/755 322/18639 0.118012422360248 2.91342190777837 3.5324780291989e-09 2.72883927755615e-07 GO:0008137 NADH dehydrogenase (ubiquinone) activity 13/755 41/18639 0.317073170731707 7.82771765465999 4.39693533936967e-09 3.13535312276591e-07 GO:0003954 NADH dehydrogenase activity 13/755 44/18639 0.295454545454545 7.29400963275136 1.15761279009828e-08 7.66505040300792e-07 GO:0003779 actin binding 44/755 443/18639 0.0993227990970655 2.45202338062279 4.13424406726706e-08 2.55496283357105e-06 GO:0050840 extracellular matrix binding 15/755 67/18639 0.223880597014925 5.52703370564397 5.47689773897486e-08 2.99659913673809e-06 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 14/755 58/18639 0.241379310344828 5.95903174240694 5.49538137265884e-08 2.99659913673809e-06 GO:0005178 integrin binding 23/755 161/18639 0.142857142857143 3.52677388836329 1.45268233153769e-07 7.48131400741913e-06 GO:0048027 mRNA 5'-UTR binding 9/755 24/18639 0.375 9.25778145695364 2.11683256068143e-07 9.87399681463464e-06 GO:0098641 cadherin binding involved in cell-cell adhesion 8/755 18/18639 0.444444444444444 10.9721854304636 2.13031214986724e-07 9.87399681463464e-06 GO:0019843 rRNA binding 14/755 65/18639 0.215384615384615 5.31728986245543 2.54011634220052e-07 1.12127992819995e-05 GO:0005201 extracellular matrix structural constituent 23/755 168/18639 0.136904761904762 3.37982497634816 3.18003518325096e-07 1.33995118857893e-05 GO:0051015 actin filament binding 26/755 209/18639 0.124401913875598 3.07116195063215 3.76655439424715e-07 1.51808518411613e-05 GO:0031386 protein tag activity 7/755 15/18639 0.466666666666667 11.5207947019868 8.42539958403191e-07 3.12413816575903e-05 GO:0141047 molecular tag activity 7/755 15/18639 0.466666666666667 11.5207947019868 8.42539958403191e-07 3.12413816575903e-05 GO:0001968 fibronectin binding 9/755 30/18639 0.3 7.40622516556291 1.86100400131486e-06 6.50345490971459e-05 GO:0098631 cell adhesion mediator activity 14/755 76/18639 0.184210526315789 4.5476821192053 1.89421016787804e-06 6.50345490971459e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 15/755 88/18639 0.170454545454545 4.20808248043347 2.27879072898837e-06 7.54442502061507e-05 GO:0001618 virus receptor activity 14/755 81/18639 0.172839506172839 4.26696100073583 4.16672272215647e-06 0.00013319144701514 GO:0140272 exogenous protein binding 14/755 82/18639 0.170731707317073 4.21492489097076 4.83988448324742e-06 0.000149552430532345 GO:0043021 ribonucleoprotein complex binding 21/755 177/18639 0.11864406779661 2.92901560220002 1.03376812170884e-05 0.000304145786711902 GO:0098632 cell-cell adhesion mediator activity 11/755 55/18639 0.2 4.93748344370861 1.04990994334206e-05 0.000304145786711902 GO:0005200 structural constituent of cytoskeleton 16/755 112/18639 0.142857142857143 3.52677388836329 1.13024963979408e-05 0.000317497398814883 GO:0004129 cytochrome-c oxidase activity 6/755 15/18639 0.4 9.87496688741722 1.58342794903514e-05 0.000419382202501592 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/755 15/18639 0.4 9.87496688741722 1.58342794903514e-05 0.000419382202501592 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/755 16/18639 0.375 9.25778145695364 2.44675702163041e-05 0.000630039933069831 GO:0051082 unfolded protein binding 16/755 121/18639 0.132231404958678 3.264451863609 3.02882762831793e-05 0.000758844111202897 GO:0140311 protein sequestering activity 8/755 33/18639 0.242424242424242 5.9848284166165 3.93815173966206e-05 0.000960701753333351 GO:1990948 ubiquitin ligase inhibitor activity 5/755 11/18639 0.454545454545455 11.2215532811559 4.0555524166788e-05 0.000963973612887499 GO:0043022 ribosome binding 15/755 112/18639 0.133928571428571 3.30635052034059 4.58030670814753e-05 0.00106148607961319 GO:0050750 low-density lipoprotein particle receptor binding 7/755 26/18639 0.269230769230769 6.64661232806928 5.8285206894649e-05 0.00131781431198389 GO:0140313 molecular sequestering activity 10/755 55/18639 0.181818181818182 4.48862131246237 6.27171811003869e-05 0.00138425778285854 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 8/755 36/18639 0.222222222222222 5.48609271523179 7.70778514939743e-05 0.00158780374077587 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 8/755 36/18639 0.222222222222222 5.48609271523179 7.70778514939743e-05 0.00158780374077587 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 8/755 36/18639 0.222222222222222 5.48609271523179 7.70778514939743e-05 0.00158780374077587 GO:0044325 transmembrane transporter binding 16/755 136/18639 0.117647058823529 2.90440202571095 0.000126047947467738 0.00254014015875202 GO:0061134 peptidase regulator activity 22/755 226/18639 0.0973451327433628 2.40319990622985 0.000135465036440266 0.0026718316761729 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/755 39/18639 0.205128205128205 5.06408558329088 0.000140751544665936 0.00271826420636089 GO:0070325 lipoprotein particle receptor binding 7/755 31/18639 0.225806451612903 5.57457808160649 0.0001952740216284 0.00369426567448014 GO:0016859 cis-trans isomerase activity 8/755 42/18639 0.19047619047619 4.70236518448439 0.000242566753300753 0.00449718760619597 GO:0031072 heat shock protein binding 15/755 131/18639 0.114503816793893 2.82680349830646 0.000273863794588369 0.004977877207518 GO:0008200 ion channel inhibitor activity 8/755 43/18639 0.186046511627907 4.59300785461266 0.00028755713454141 0.0050679030316029 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/755 54/18639 0.166666666666667 4.11456953642384 0.000289750658764783 0.0050679030316029 GO:0071889 14-3-3 protein binding 7/755 33/18639 0.212121212121212 5.23672486453943 0.000295652272991624 0.00507536401968955 GO:0016248 channel inhibitor activity 8/755 44/18639 0.181818181818182 4.48862131246237 0.000339136973298359 0.00571599953177416 GO:0048306 calcium-dependent protein binding 11/755 80/18639 0.1375 3.39451986754967 0.000366882425724773 0.00607321444012259 GO:0141110 transporter inhibitor activity 8/755 45/18639 0.177777777777778 4.38887417218543 0.000398011076819208 0.00646582688986013 GO:0002020 protease binding 15/755 136/18639 0.110294117647059 2.72287689910401 0.00041152512028236 0.00646582688986013 GO:0019838 growth factor binding 15/755 136/18639 0.110294117647059 2.72287689910401 0.00041152512028236 0.00646582688986013 GO:0005528 FK506 binding 4/755 10/18639 0.4 9.87496688741722 0.00046121054642771 0.00712570294230813 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 5/755 18/18639 0.277777777777778 6.85761589403973 0.000593606679140309 0.00902087527152567 GO:0043394 proteoglycan binding 7/755 37/18639 0.189189189189189 4.67059244675139 0.000618990566215487 0.00925490733680252 GO:0019207 kinase regulator activity 24/755 287/18639 0.0836236933797909 2.06445300782242 0.000666621962413128 0.00980886601836459 GO:0016209 antioxidant activity 11/755 86/18639 0.127906976744186 3.1576929000462 0.000687914793702609 0.00996401584003623 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 4/755 11/18639 0.363636363636364 8.97724262492475 0.000701584844862522 0.0100056792490394 GO:0097718 disordered domain specific binding 6/755 28/18639 0.214285714285714 5.29016083254494 0.000759454352592221 0.0106668815886817 GO:0042288 MHC class I protein binding 5/755 20/18639 0.25 6.17185430463576 0.00100423024925639 0.0131167228535887 GO:0043024 ribosomal small subunit binding 5/755 20/18639 0.25 6.17185430463576 0.00100423024925639 0.0131167228535887 GO:0015036 disulfide oxidoreductase activity 7/755 40/18639 0.175 4.32029801324503 0.00100888941723903 0.0131167228535887 GO:0140662 ATP-dependent protein folding chaperone 7/755 40/18639 0.175 4.32029801324503 0.00100888941723903 0.0131167228535887 GO:0004859 phospholipase inhibitor activity 4/755 12/18639 0.333333333333333 8.22913907284768 0.00101877459057 0.0131167228535887 GO:0005527 macrolide binding 4/755 12/18639 0.333333333333333 8.22913907284768 0.00101877459057 0.0131167228535887 GO:0005080 protein kinase C binding 8/755 52/18639 0.153846153846154 3.79806418746816 0.00108311398134598 0.0137540638453113 GO:0042287 MHC protein binding 7/755 41/18639 0.170731707317073 4.21492489097076 0.00117470369618453 0.0147155449508522 GO:0015485 cholesterol binding 8/755 54/18639 0.148148148148148 3.65739514348786 0.00139488873691899 0.0172408247883188 GO:0044548 S100 protein binding 4/755 14/18639 0.285714285714286 7.05354777672659 0.00193099806302393 0.0235530947950419 GO:0004860 protein kinase inhibitor activity 10/755 84/18639 0.119047619047619 2.93897824030274 0.00206535472792418 0.0248647251011132 GO:0019903 protein phosphatase binding 14/755 144/18639 0.0972222222222222 2.40016556291391 0.00215937980683346 0.0256633984735208 GO:0015035 protein-disulfide reductase activity 6/755 34/18639 0.176470588235294 4.35660303856642 0.00220554504865946 0.0258802564570546 GO:0050431 transforming growth factor beta binding 5/755 24/18639 0.208333333333333 5.1432119205298 0.00240741086682785 0.0278958734193677 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/755 59/18639 0.135593220338983 3.34744640251431 0.00249025340111924 0.028499566701698 GO:0033218 amide binding 20/755 247/18639 0.0809716599190283 1.99898115129903 0.0026372239709914 0.0298134953793784 GO:0055106 ubiquitin-protein transferase regulator activity 6/755 36/18639 0.166666666666667 4.11456953642384 0.00298258281638204 0.0333114972383874 GO:0051087 protein-folding chaperone binding 13/755 134/18639 0.0970149253731343 2.39504793911239 0.00311829873440156 0.0344126538903601 GO:0003725 double-stranded RNA binding 9/755 75/18639 0.12 2.96249006622517 0.00322059784391485 0.0350701453979237 GO:0005159 insulin-like growth factor receptor binding 4/755 16/18639 0.25 6.17185430463576 0.0032913728690608 0.0350701453979237 GO:0055102 lipase inhibitor activity 4/755 16/18639 0.25 6.17185430463576 0.0032913728690608 0.0350701453979237 GO:0061135 endopeptidase regulator activity 16/755 184/18639 0.0869565217391304 2.14673193204722 0.00339172037349175 0.0355038873951097 GO:0023023 MHC protein complex binding 6/755 37/18639 0.162162162162162 4.00336495435833 0.00344005228415621 0.0355038873951097 GO:0019210 kinase inhibitor activity 10/755 90/18639 0.111111111111111 2.74304635761589 0.00344697935874852 0.0355038873951097 GO:0030414 peptidase inhibitor activity 15/755 169/18639 0.0887573964497041 2.19119087738548 0.00369512496996138 0.0376415477709253 GO:0015252 proton channel activity 5/755 27/18639 0.185185185185185 4.57174392935982 0.00413641195350673 0.04110030403073 GO:0023026 MHC class II protein complex binding 5/755 27/18639 0.185185185185185 4.57174392935982 0.00413641195350673 0.04110030403073 GO:0016018 cyclosporin A binding 4/755 17/18639 0.235294117647059 5.80880405142189 0.00416766836989064 0.04110030403073 GO:0046332 SMAD binding 9/755 79/18639 0.113924050632911 2.81249056920111 0.00457593138702254 0.0446514567975778 GO:0003746 translation elongation factor activity 4/755 18/18639 0.222222222222222 5.48609271523179 0.00518882885296217 0.0495880860484117 GO:0070064 proline-rich region binding 4/755 18/18639 0.222222222222222 5.48609271523179 0.00518882885296217 0.0495880860484117 GO:0140297 DNA-binding transcription factor binding 32/755 488/18639 0.0655737704918033 1.61884703072413 0.00527571441772925 0.0496208676046444 GO:0005544 calcium-dependent phospholipid binding 7/755 53/18639 0.132075471698113 3.26060227414719 0.00529931595777755 0.0496208676046444 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/755 128/18639 0.09375 2.31444536423841 0.00581138020081824 0.0538714944615851 GO:0004866 endopeptidase inhibitor activity 14/755 161/18639 0.0869565217391304 2.14673193204722 0.00591255892669066 0.0542667537132896 GO:0032934 sterol binding 8/755 68/18639 0.117647058823529 2.90440202571095 0.00604326799547859 0.0549226414883201 GO:0005525 GTP binding 26/755 378/18639 0.0687830687830688 1.69807631661936 0.00622133030004649 0.0550698806576843 GO:0008135 translation factor activity, RNA binding 9/755 83/18639 0.108433734939759 2.67694885502274 0.00633845102672429 0.0550698806576843 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/755 19/18639 0.210526315789474 5.19735099337748 0.00636480035819742 0.0550698806576843 GO:0005131 growth hormone receptor binding 3/755 10/18639 0.3 7.40622516556291 0.00641590842613798 0.0550698806576843 GO:0005522 profilin binding 3/755 10/18639 0.3 7.40622516556291 0.00641590842613798 0.0550698806576843 GO:0030957 Tat protein binding 3/755 10/18639 0.3 7.40622516556291 0.00641590842613798 0.0550698806576843 GO:0180051 translation factor activity 9/755 84/18639 0.107142857142857 2.64508041627247 0.00685122258258029 0.0572219169085119 GO:0019001 guanyl nucleotide binding 27/755 400/18639 0.0675 1.66640066225166 0.00685181529325223 0.0572219169085119 GO:0032561 guanyl ribonucleotide binding 27/755 400/18639 0.0675 1.66640066225166 0.00685181529325223 0.0572219169085119 GO:0097110 scaffold protein binding 8/755 70/18639 0.114285714285714 2.82141911069063 0.00719391336728849 0.0595424793881824 GO:0004601 peroxidase activity 7/755 57/18639 0.12280701754386 3.0317880794702 0.00791213973328752 0.064338188883838 GO:0016504 peptidase activator activity 7/755 57/18639 0.12280701754386 3.0317880794702 0.00791213973328752 0.064338188883838 GO:0019887 protein kinase regulator activity 19/755 255/18639 0.0745098039215686 1.8394546162836 0.00803721375998588 0.0647869317870166 GO:0050786 RAGE receptor binding 3/755 11/18639 0.272727272727273 6.73293196869356 0.00855877976911627 0.0672371936099219 GO:0050998 nitric-oxide synthase binding 3/755 11/18639 0.272727272727273 6.73293196869356 0.00855877976911627 0.0672371936099219 GO:0070990 snRNP binding 3/755 11/18639 0.272727272727273 6.73293196869356 0.00855877976911627 0.0672371936099219 GO:0001786 phosphatidylserine binding 7/755 59/18639 0.11864406779661 2.92901560220002 0.00952687833806099 0.0742135816754835 GO:0005516 calmodulin binding 16/755 207/18639 0.0772946859903382 1.90820616181975 0.01029233340803 0.0795082755770321 GO:0019902 phosphatase binding 15/755 190/18639 0.0789473684210526 1.94900662251656 0.0106174877850292 0.0813422411299346 GO:0044183 protein folding chaperone 8/755 75/18639 0.106666666666667 2.63332450331126 0.0107885916368859 0.0819756102245346 GO:0017166 vinculin binding 3/755 12/18639 0.25 6.17185430463576 0.0110721148286317 0.083445938586517 GO:0019888 protein phosphatase regulator activity 10/755 107/18639 0.0934579439252336 2.30723525406944 0.0115098476433581 0.086045393269298 GO:0017022 myosin binding 8/755 76/18639 0.105263157894737 2.59867549668874 0.01164311681154 0.0862504470645524 GO:0022804 active transmembrane transporter activity 29/755 457/18639 0.0634573304157549 1.56659759154868 0.0117233617369295 0.0862504470645524 GO:0043178 alcohol binding 9/755 92/18639 0.0978260869565217 2.41507342355312 0.0121760986638104 0.0888759327665533 GO:0017134 fibroblast growth factor binding 4/755 23/18639 0.173913043478261 4.29346386409444 0.0127943661508212 0.0919409102465989 GO:0070577 lysine-acetylated histone binding 4/755 23/18639 0.173913043478261 4.29346386409444 0.0127943661508212 0.0919409102465989 GO:0099106 ion channel regulator activity 13/755 160/18639 0.08125 2.00585264900662 0.0133740863733183 0.0953675236005079 GO:0140033 acetylation-dependent protein binding 4/755 24/18639 0.166666666666667 4.11456953642384 0.0148717572076199 0.105237549095142 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 23/755 349/18639 0.0659025787965616 1.62696445852862 0.0154888417119508 0.108773911113473 GO:0008191 metalloendopeptidase inhibitor activity 3/755 14/18639 0.214285714285714 5.29016083254494 0.01724872680612 0.119325147382636 GO:0008494 translation activator activity 3/755 14/18639 0.214285714285714 5.29016083254494 0.01724872680612 0.119325147382636 GO:0043531 ADP binding 5/755 38/18639 0.131578947368421 3.24834437086093 0.0178619821337078 0.122652277318127 GO:0001221 transcription coregulator binding 10/755 115/18639 0.0869565217391304 2.14673193204722 0.0183619195510384 0.125158083998622 GO:0001664 G protein-coupled receptor binding 20/755 297/18639 0.0673400673400673 1.66245233794903 0.0186292954570907 0.126053699917687 GO:0016247 channel regulator activity 13/755 168/18639 0.0773809523809524 1.91033585619678 0.0193299016348007 0.129846513155509 GO:0050681 nuclear androgen receptor binding 4/755 26/18639 0.153846153846154 3.79806418746816 0.0196347437748366 0.130010053423382 GO:0070412 R-SMAD binding 4/755 26/18639 0.153846153846154 3.79806418746816 0.0196347437748366 0.130010053423382 GO:0019208 phosphatase regulator activity 10/755 117/18639 0.0854700854700855 2.11003565970453 0.020465016361569 0.134546596930315 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/755 15/18639 0.2 4.93748344370861 0.0209235424547825 0.134695304552662 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/755 15/18639 0.2 4.93748344370861 0.0209235424547825 0.134695304552662 GO:0050780 dopamine receptor binding 3/755 15/18639 0.2 4.93748344370861 0.0209235424547825 0.134695304552662 GO:0141108 transporter regulator activity 13/755 170/18639 0.0764705882352941 1.88786131671212 0.0210898057616799 0.134829309938464 GO:0035255 ionotropic glutamate receptor binding 4/755 27/18639 0.148148148148148 3.65739514348786 0.02233010583072 0.141780877432037 GO:0016922 nuclear receptor binding 11/755 137/18639 0.0802919708029197 1.98220138251076 0.0235599048560743 0.148571644908713 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/755 16/18639 0.1875 4.62889072847682 0.0249925046668721 0.154950411132379 GO:0008142 oxysterol binding 3/755 16/18639 0.1875 4.62889072847682 0.0249925046668721 0.154950411132379 GO:0046875 ephrin receptor binding 4/755 28/18639 0.142857142857143 3.52677388836329 0.0252400346073239 0.154950411132379 GO:0051019 mitogen-activated protein kinase binding 4/755 28/18639 0.142857142857143 3.52677388836329 0.0252400346073239 0.154950411132379 GO:0008307 structural constituent of muscle 5/755 42/18639 0.119047619047619 2.93897824030274 0.026545895477962 0.161895033605729 GO:0030169 low-density lipoprotein particle binding 3/755 17/18639 0.176470588235294 4.35660303856642 0.0294549695876538 0.175030492357404 GO:0032977 membrane insertase activity 3/755 17/18639 0.176470588235294 4.35660303856642 0.0294549695876538 0.175030492357404 GO:0048038 quinone binding 3/755 17/18639 0.176470588235294 4.35660303856642 0.0294549695876538 0.175030492357404 GO:0051787 misfolded protein binding 3/755 17/18639 0.176470588235294 4.35660303856642 0.0294549695876538 0.175030492357404 GO:0072341 modified amino acid binding 8/755 91/18639 0.0879120879120879 2.17032239283895 0.0311356650500612 0.18383924523189 GO:0051721 protein phosphatase 2A binding 4/755 30/18639 0.133333333333333 3.29165562913907 0.0317153490334017 0.183916510421071 GO:0001046 core promoter sequence-specific DNA binding 5/755 44/18639 0.113636363636364 2.80538832028898 0.0317439500187394 0.183916510421071 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/755 44/18639 0.113636363636364 2.80538832028898 0.0317439500187394 0.183916510421071 GO:0019955 cytokine binding 11/755 144/18639 0.0763888888888889 1.88584437086093 0.0324130684055969 0.18662679758999 GO:0004867 serine-type endopeptidase inhibitor activity 8/755 95/18639 0.0842105263157895 2.07894039735099 0.0387821714071139 0.215650653273244 GO:0030515 snoRNA binding 4/755 32/18639 0.125 3.08592715231788 0.0390774248393447 0.215650653273244 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/755 32/18639 0.125 3.08592715231788 0.0390774248393447 0.215650653273244 GO:0051059 NF-kappaB binding 4/755 32/18639 0.125 3.08592715231788 0.0390774248393447 0.215650653273244 GO:0140142 nucleocytoplasmic carrier activity 4/755 32/18639 0.125 3.08592715231788 0.0390774248393447 0.215650653273244 GO:0005229 intracellularly calcium-gated chloride channel activity 3/755 19/18639 0.157894736842105 3.89801324503311 0.0395475847426661 0.215650653273244 GO:0050145 nucleoside monophosphate kinase activity 3/755 19/18639 0.157894736842105 3.89801324503311 0.0395475847426661 0.215650653273244 GO:0070003 threonine-type peptidase activity 3/755 19/18639 0.157894736842105 3.89801324503311 0.0395475847426661 0.215650653273244 GO:0141147 intracellularly calcium-gated channel activity 3/755 19/18639 0.157894736842105 3.89801324503311 0.0395475847426661 0.215650653273244 GO:0043495 protein-membrane adaptor activity 5/755 47/18639 0.106382978723404 2.62632098069607 0.0406595370850478 0.22041749051368 GO:0005507 copper ion binding 6/755 63/18639 0.0952380952380952 2.35118259224219 0.0417599399257801 0.225066652972083 GO:0019956 chemokine binding 4/755 33/18639 0.121212121212121 2.99241420830825 0.0430933635720908 0.230910682262013 GO:0042277 peptide binding 16/755 249/18639 0.0642570281124498 1.5863400622357 0.0470008040844017 0.245963565604116 GO:0008376 acetylgalactosaminyltransferase activity 4/755 34/18639 0.117647058823529 2.90440202571095 0.0473325898797605 0.245963565604116 GO:0051427 hormone receptor binding 4/755 34/18639 0.117647058823529 2.90440202571095 0.0473325898797605 0.245963565604116 GO:0001222 transcription corepressor binding 5/755 49/18639 0.102040816326531 2.51912420597378 0.047365045890884 0.245963565604116 GO:0035254 glutamate receptor binding 5/755 49/18639 0.102040816326531 2.51912420597378 0.047365045890884 0.245963565604116 GO:0120013 lipid transfer activity 6/755 65/18639 0.0923076923076923 2.2788385124809 0.0474945827865552 0.245963565604116 GO:1990782 protein tyrosine kinase binding 9/755 117/18639 0.0769230769230769 1.89903209373408 0.0481502578280114 0.247973827814259 GO:0003924 GTPase activity 20/755 331/18639 0.0604229607250755 1.49168684099958 0.0495275134128159 0.253657485821438 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/755 21/18639 0.142857142857143 3.52677388836329 0.0511583556916865 0.260570306187876 GO:0016229 steroid dehydrogenase activity 4/755 35/18639 0.114285714285714 2.82141911069063 0.0517943855831399 0.262368281068692 GO:0005048 signal sequence binding 5/755 51/18639 0.0980392156862745 2.42033502142579 0.0546870374750346 0.275515672496506 GO:1901681 sulfur compound binding 17/755 275/18639 0.0618181818181818 1.52613124623721 0.055937122231592 0.280290336803707 GO:0005548 phospholipid transporter activity 6/755 68/18639 0.0882352941176471 2.17830151928321 0.0569674353963698 0.283918347378682 GO:0008093 cytoskeletal anchor activity 3/755 22/18639 0.136363636363636 3.36646598434678 0.0575130432014273 0.285104764961086 GO:0005319 lipid transporter activity 12/755 178/18639 0.0674157303370786 1.66432026192425 0.0585715191450675 0.288437357410284 GO:0042975 peroxisome proliferator activated receptor binding 2/755 10/18639 0.2 4.93748344370861 0.0594299193801124 0.288437357410284 GO:0050815 phosphoserine residue binding 2/755 10/18639 0.2 4.93748344370861 0.0594299193801124 0.288437357410284 GO:0070513 death domain binding 2/755 10/18639 0.2 4.93748344370861 0.0594299193801124 0.288437357410284 GO:0004864 protein phosphatase inhibitor activity 5/755 53/18639 0.0943396226415094 2.32900162439085 0.0626266802879881 0.302369440765443 GO:0030246 carbohydrate binding 17/755 280/18639 0.0607142857142857 1.4988789025544 0.0639177858840034 0.30529601585441 GO:0004602 glutathione peroxidase activity 3/755 23/18639 0.130434782608696 3.22009789807083 0.0642208447590182 0.30529601585441 GO:0031681 G-protein beta-subunit binding 3/755 23/18639 0.130434782608696 3.22009789807083 0.0642208447590182 0.30529601585441 GO:0000146 microfilament motor activity 4/755 38/18639 0.105263157894737 2.59867549668874 0.0664998351958287 0.314517077686394 GO:0005539 glycosaminoglycan binding 15/755 242/18639 0.0619834710743802 1.53021181106672 0.0681446040260222 0.320660141787424 GO:0002162 dystroglycan binding 2/755 11/18639 0.181818181818182 4.48862131246237 0.0707346170714448 0.323009803079948 GO:0010854 adenylate cyclase regulator activity 2/755 11/18639 0.181818181818182 4.48862131246237 0.0707346170714448 0.323009803079948 GO:0034511 U3 snoRNA binding 2/755 11/18639 0.181818181818182 4.48862131246237 0.0707346170714448 0.323009803079948 GO:0048407 platelet-derived growth factor binding 2/755 11/18639 0.181818181818182 4.48862131246237 0.0707346170714448 0.323009803079948 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/755 11/18639 0.181818181818182 4.48862131246237 0.0707346170714448 0.323009803079948 GO:0140031 phosphorylation-dependent protein binding 2/755 11/18639 0.181818181818182 4.48862131246237 0.0707346170714448 0.323009803079948 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/755 39/18639 0.102564102564103 2.53204279164544 0.0718340226183719 0.325081554561838 GO:0005496 steroid binding 8/755 108/18639 0.0740740740740741 1.82869757174393 0.0718896641695543 0.325081554561838 GO:0019212 phosphatase inhibitor activity 5/755 56/18639 0.0892857142857143 2.20423368022706 0.0756865902187955 0.34058965598458 GO:0071949 FAD binding 4/755 40/18639 0.1 2.4687417218543 0.0773794027571025 0.346358623460528 GO:0019209 kinase activator activity 10/755 148/18639 0.0675675675675676 1.66806873098264 0.0784976328296804 0.346358623460528 GO:0005537 D-mannose binding 3/755 25/18639 0.12 2.96249006622517 0.0786507933227931 0.346358623460528 GO:0042974 nuclear retinoic acid receptor binding 3/755 25/18639 0.12 2.96249006622517 0.0786507933227931 0.346358623460528 GO:0035591 signaling adaptor activity 9/755 129/18639 0.0697674418604651 1.72237794547975 0.0788367524813069 0.346358623460528 GO:0140104 molecular carrier activity 15/755 249/18639 0.0602409638554217 1.48719380834597 0.0822657008640818 0.35642985088859 GO:0005049 nuclear export signal receptor activity 2/755 12/18639 0.166666666666667 4.11456953642384 0.0826671175200074 0.35642985088859 GO:0010853 cyclase activator activity 2/755 12/18639 0.166666666666667 4.11456953642384 0.0826671175200074 0.35642985088859 GO:0070008 serine-type exopeptidase activity 2/755 12/18639 0.166666666666667 4.11456953642384 0.0826671175200074 0.35642985088859 GO:0042562 hormone binding 7/755 94/18639 0.074468085106383 1.83842468648725 0.0868088271995259 0.372554550064632 GO:0031492 nucleosomal DNA binding 4/755 42/18639 0.0952380952380952 2.35118259224219 0.0890888066185777 0.378831760254227 GO:0051879 Hsp90 protein binding 4/755 42/18639 0.0952380952380952 2.35118259224219 0.0890888066185777 0.378831760254227 GO:0036002 pre-mRNA binding 5/755 59/18639 0.0847457627118644 2.09215400157144 0.0901019286255347 0.381390355414935 GO:0051020 GTPase binding 18/755 315/18639 0.0571428571428571 1.41070955534532 0.0905229968953258 0.381430991463487 GO:0001671 ATPase activator activity 3/755 27/18639 0.111111111111111 2.74304635761589 0.0943508430516655 0.392051639814141 GO:0004364 glutathione transferase activity 3/755 27/18639 0.111111111111111 2.74304635761589 0.0943508430516655 0.392051639814141 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/755 13/18639 0.153846153846154 3.79806418746816 0.0951581650034323 0.392051639814141 GO:0030955 potassium ion binding 2/755 13/18639 0.153846153846154 3.79806418746816 0.0951581650034323 0.392051639814141 GO:0031994 insulin-like growth factor I binding 2/755 13/18639 0.153846153846154 3.79806418746816 0.0951581650034323 0.392051639814141 GO:0030547 signaling receptor inhibitor activity 4/755 44/18639 0.0909090909090909 2.24431065623119 0.101594469165029 0.415507064804552 GO:0019789 SUMO transferase activity 3/755 28/18639 0.107142857142857 2.64508041627247 0.102644140064986 0.415507064804552 GO:0046625 sphingolipid binding 3/755 28/18639 0.107142857142857 2.64508041627247 0.102644140064986 0.415507064804552 GO:0051393 alpha-actinin binding 3/755 28/18639 0.107142857142857 2.64508041627247 0.102644140064986 0.415507064804552 GO:0032036 myosin heavy chain binding 2/755 14/18639 0.142857142857143 3.52677388836329 0.108143071369651 0.432106151550286 GO:0071933 Arp2/3 complex binding 2/755 14/18639 0.142857142857143 3.52677388836329 0.108143071369651 0.432106151550286 GO:1990825 sequence-specific mRNA binding 2/755 14/18639 0.142857142857143 3.52677388836329 0.108143071369651 0.432106151550286 GO:0043130 ubiquitin binding 7/755 100/18639 0.07 1.72811920529801 0.11111422463472 0.440580540276007 GO:0003785 actin monomer binding 3/755 29/18639 0.103448275862069 2.55387074674583 0.11121450531239 0.440580540276007 GO:0031267 small GTPase binding 16/755 283/18639 0.0565371024734982 1.39575503709077 0.113146373004217 0.446326330957061 GO:0030291 protein serine/threonine kinase inhibitor activity 4/755 46/18639 0.0869565217391304 2.14673193204722 0.114857500180094 0.449527559264656 GO:0016853 isomerase activity 11/755 180/18639 0.0611111111111111 1.50867549668874 0.114927757870252 0.449527559264656 GO:0031210 phosphatidylcholine binding 3/755 30/18639 0.1 2.4687417218543 0.120047744898944 0.463734460172153 GO:0098918 structural constituent of synapse 3/755 30/18639 0.1 2.4687417218543 0.120047744898944 0.463734460172153 GO:0005523 tropomyosin binding 2/755 15/18639 0.133333333333333 3.29165562913907 0.121561460433477 0.463734460172153 GO:0015929 hexosaminidase activity 2/755 15/18639 0.133333333333333 3.29165562913907 0.121561460433477 0.463734460172153 GO:0033130 acetylcholine receptor binding 2/755 15/18639 0.133333333333333 3.29165562913907 0.121561460433477 0.463734460172153 GO:0050700 CARD domain binding 2/755 15/18639 0.133333333333333 3.29165562913907 0.121561460433477 0.463734460172153 GO:0051117 ATPase binding 6/755 84/18639 0.0714285714285714 1.76338694418165 0.125091284454584 0.474189557546043 GO:0016887 ATP hydrolysis activity 22/755 417/18639 0.052757793764988 1.30245366620611 0.12532517971821 0.474189557546043 GO:0008237 metallopeptidase activity 11/755 184/18639 0.0597826086956522 1.47587820328246 0.128220375773231 0.483171903828396 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/755 16/18639 0.125 3.08592715231788 0.135357025542992 0.496624903266949 GO:0005024 transforming growth factor beta receptor activity 2/755 16/18639 0.125 3.08592715231788 0.135357025542992 0.496624903266949 GO:0005521 lamin binding 2/755 16/18639 0.125 3.08592715231788 0.135357025542992 0.496624903266949 GO:0008296 3'-5'-DNA exonuclease activity 2/755 16/18639 0.125 3.08592715231788 0.135357025542992 0.496624903266949 GO:0043023 ribosomal large subunit binding 2/755 16/18639 0.125 3.08592715231788 0.135357025542992 0.496624903266949 GO:0070411 I-SMAD binding 2/755 16/18639 0.125 3.08592715231788 0.135357025542992 0.496624903266949 GO:0050660 flavin adenine dinucleotide binding 6/755 86/18639 0.0697674418604651 1.72237794547975 0.135587444855022 0.496624903266949 GO:0060590 ATPase regulator activity 4/755 49/18639 0.0816326530612245 2.01529936477902 0.136076294962033 0.496624903266949 GO:0071813 lipoprotein particle binding 3/755 32/18639 0.09375 2.31444536423841 0.138445206754515 0.499372399460839 GO:0071814 protein-lipid complex binding 3/755 32/18639 0.09375 2.31444536423841 0.138445206754515 0.499372399460839 GO:0120015 sterol transfer activity 3/755 32/18639 0.09375 2.31444536423841 0.138445206754515 0.499372399460839 GO:1990841 promoter-specific chromatin binding 5/755 68/18639 0.0735294117647059 1.81525126606934 0.140953539806456 0.506449346513895 GO:0004197 cysteine-type endopeptidase activity 6/755 88/18639 0.0681818181818182 1.68323299217339 0.146483392777153 0.520922769903884 GO:0030296 protein tyrosine kinase activator activity 3/755 33/18639 0.0909090909090909 2.24431065623119 0.147980391072758 0.520922769903884 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/755 17/18639 0.117647058823529 2.90440202571095 0.14947729967037 0.520922769903884 GO:0030548 acetylcholine receptor regulator activity 2/755 17/18639 0.117647058823529 2.90440202571095 0.14947729967037 0.520922769903884 GO:0046965 nuclear retinoid X receptor binding 2/755 17/18639 0.117647058823529 2.90440202571095 0.14947729967037 0.520922769903884 GO:0070402 NADPH binding 2/755 17/18639 0.117647058823529 2.90440202571095 0.14947729967037 0.520922769903884 GO:0070492 oligosaccharide binding 2/755 17/18639 0.117647058823529 2.90440202571095 0.14947729967037 0.520922769903884 GO:1990226 histone methyltransferase binding 2/755 17/18639 0.117647058823529 2.90440202571095 0.14947729967037 0.520922769903884 GO:0003743 translation initiation factor activity 4/755 51/18639 0.0784313725490196 1.93626801714063 0.151035421050495 0.524381405669696 GO:0004222 metalloendopeptidase activity 7/755 110/18639 0.0636363636363636 1.57101745936183 0.158645722905025 0.54874845198865 GO:0008201 heparin binding 10/755 172/18639 0.0581395348837209 1.43531495456646 0.160953867291081 0.550401001743629 GO:0000900 mRNA regulatory element binding translation repressor activity 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0008308 voltage-gated monoatomic anion channel activity 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0017128 phospholipid scramblase activity 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0035615 clathrin adaptor activity 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0070628 proteasome binding 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0099602 neurotransmitter receptor regulator activity 2/755 18/18639 0.111111111111111 2.74304635761589 0.163873437412343 0.550401001743629 GO:0005246 calcium channel regulator activity 4/755 53/18639 0.0754716981132075 1.86320129951268 0.166586051016153 0.555486580186956 GO:0051018 protein kinase A binding 4/755 53/18639 0.0754716981132075 1.86320129951268 0.166586051016153 0.555486580186956 GO:0005154 epidermal growth factor receptor binding 3/755 35/18639 0.0857142857142857 2.11606433301798 0.167651074173362 0.557034214188912 GO:0003925 G protein activity 4/755 54/18639 0.0740740740740741 1.82869757174393 0.174566747785492 0.568623737827105 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/755 54/18639 0.0740740740740741 1.82869757174393 0.174566747785492 0.568623737827105 GO:0005484 SNAP receptor activity 3/755 36/18639 0.0833333333333333 2.05728476821192 0.177757764839654 0.568623737827105 GO:0016409 palmitoyltransferase activity 3/755 36/18639 0.0833333333333333 2.05728476821192 0.177757764839654 0.568623737827105 GO:0003756 protein disulfide isomerase activity 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0005520 insulin-like growth factor binding 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0031420 alkali metal ion binding 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0043395 heparan sulfate proteoglycan binding 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0097001 ceramide binding 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0140036 ubiquitin-modified protein reader activity 2/755 19/18639 0.105263157894737 2.59867549668874 0.178500008314657 0.568623737827105 GO:0048029 monosaccharide binding 5/755 74/18639 0.0675675675675676 1.66806873098264 0.180422389290179 0.572779297506835 GO:0017124 SH3 domain binding 7/755 115/18639 0.0608695652173913 1.50271235243306 0.185376750140504 0.586499137816544 GO:0030551 cyclic nucleotide binding 3/755 37/18639 0.0810810810810811 2.00168247717917 0.18802638574998 0.590849015560107 GO:0042805 actinin binding 3/755 37/18639 0.0810810810810811 2.00168247717917 0.18802638574998 0.590849015560107 GO:0010851 cyclase regulator activity 2/755 20/18639 0.1 2.4687417218543 0.193314800962711 0.597342734974776 GO:0015095 magnesium ion transmembrane transporter activity 2/755 20/18639 0.1 2.4687417218543 0.193314800962711 0.597342734974776 GO:0016408 C-acyltransferase activity 2/755 20/18639 0.1 2.4687417218543 0.193314800962711 0.597342734974776 GO:0016505 peptidase activator activity involved in apoptotic process 2/755 20/18639 0.1 2.4687417218543 0.193314800962711 0.597342734974776 GO:0061608 nuclear import signal receptor activity 2/755 20/18639 0.1 2.4687417218543 0.193314800962711 0.597342734974776 GO:0042162 telomeric DNA binding 3/755 38/18639 0.0789473684210526 1.94900662251656 0.19844294722605 0.611151535144678 GO:0042626 ATPase-coupled transmembrane transporter activity 6/755 98/18639 0.0612244897959184 1.51147452358427 0.206339231591777 0.63036368199262 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/755 21/18639 0.0952380952380952 2.35118259224219 0.208278637307029 0.63036368199262 GO:0001846 opsonin binding 2/755 21/18639 0.0952380952380952 2.35118259224219 0.208278637307029 0.63036368199262 GO:0072542 protein phosphatase activator activity 2/755 21/18639 0.0952380952380952 2.35118259224219 0.208278637307029 0.63036368199262 GO:0140312 cargo adaptor activity 2/755 21/18639 0.0952380952380952 2.35118259224219 0.208278637307029 0.63036368199262 GO:0019199 transmembrane receptor protein kinase activity 5/755 78/18639 0.0641025641025641 1.5825267447784 0.208761219386984 0.63036368199262 GO:0032182 ubiquitin-like protein binding 7/755 120/18639 0.0583333333333333 1.44009933774834 0.213813501079659 0.643523102275466 GO:0050997 quaternary ammonium group binding 3/755 40/18639 0.075 1.85155629139073 0.219665119715215 0.658995359145645 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/755 22/18639 0.0909090909090909 2.24431065623119 0.223355196717589 0.65909422827501 GO:0031683 G-protein beta/gamma-subunit complex binding 2/755 22/18639 0.0909090909090909 2.24431065623119 0.223355196717589 0.65909422827501 GO:0061133 endopeptidase activator activity 2/755 22/18639 0.0909090909090909 2.24431065623119 0.223355196717589 0.65909422827501 GO:0070034 telomerase RNA binding 2/755 22/18639 0.0909090909090909 2.24431065623119 0.223355196717589 0.65909422827501 GO:0140035 ubiquitin-like protein reader activity 2/755 22/18639 0.0909090909090909 2.24431065623119 0.223355196717589 0.65909422827501 GO:0005085 guanyl-nucleotide exchange factor activity 12/755 230/18639 0.0521739130434783 1.28803915922833 0.223964058151702 0.65909422827501 GO:0005126 cytokine receptor binding 14/755 275/18639 0.0509090909090909 1.25681396748946 0.226711574433389 0.665068447784024 GO:0017080 sodium channel regulator activity 3/755 41/18639 0.0731707317073171 1.80639638184461 0.230444023464503 0.672607078510122 GO:0030971 receptor tyrosine kinase binding 5/755 81/18639 0.0617283950617284 1.52391464311994 0.230898225765777 0.672607078510122 GO:0008238 exopeptidase activity 6/755 102/18639 0.0588235294117647 1.45220101285547 0.232416586378277 0.672607078510122 GO:0140597 protein carrier chaperone 10/755 188/18639 0.0531914893617021 1.31316049034803 0.232671318011844 0.672607078510122 GO:0015026 coreceptor activity 4/755 61/18639 0.0655737704918033 1.61884703072413 0.233634821230053 0.672607078510122 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 4/755 61/18639 0.0655737704918033 1.61884703072413 0.233634821230053 0.672607078510122 GO:0016874 ligase activity 9/755 167/18639 0.0538922155688623 1.33045961058016 0.236786016975753 0.679568537883971 GO:0099186 structural constituent of postsynapse 2/755 23/18639 0.0869565217391304 2.14673193204722 0.238510849285072 0.679874249543627 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/755 23/18639 0.0869565217391304 2.14673193204722 0.238510849285072 0.679874249543627 GO:0005253 monoatomic anion channel activity 6/755 103/18639 0.058252427184466 1.43810197389571 0.239092778156658 0.679874249543627 GO:0003713 transcription coactivator activity 13/755 256/18639 0.05078125 1.25365790562914 0.240062154588327 0.680543172181588 GO:0042056 chemoattractant activity 3/755 42/18639 0.0714285714285714 1.76338694418165 0.24131750168342 0.682016231891862 GO:0005254 chloride channel activity 5/755 83/18639 0.0602409638554217 1.48719380834597 0.24601481299763 0.693178515649858 GO:0048156 tau protein binding 3/755 43/18639 0.0697674418604651 1.72237794547975 0.252272982661934 0.699980177269967 GO:0005540 hyaluronic acid binding 2/755 24/18639 0.0833333333333333 2.05728476821192 0.25371449791015 0.699980177269967 GO:0030552 cAMP binding 2/755 24/18639 0.0833333333333333 2.05728476821192 0.25371449791015 0.699980177269967 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/755 24/18639 0.0833333333333333 2.05728476821192 0.25371449791015 0.699980177269967 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/755 24/18639 0.0833333333333333 2.05728476821192 0.25371449791015 0.699980177269967 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/755 24/18639 0.0833333333333333 2.05728476821192 0.25371449791015 0.699980177269967 GO:0070300 phosphatidic acid binding 2/755 24/18639 0.0833333333333333 2.05728476821192 0.25371449791015 0.699980177269967 GO:0001223 transcription coactivator binding 3/755 44/18639 0.0681818181818182 1.68323299217339 0.263298239747073 0.718458203013062 GO:0019205 nucleobase-containing compound kinase activity 3/755 44/18639 0.0681818181818182 1.68323299217339 0.263298239747073 0.718458203013062 GO:0000030 mannosyltransferase activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0008139 nuclear localization sequence binding 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0015662 P-type ion transporter activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0019211 phosphatase activator activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0019707 protein-cysteine S-acyltransferase activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0120020 cholesterol transfer activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0140358 P-type transmembrane transporter activity 2/755 25/18639 0.08 1.97499337748344 0.268937428743832 0.718458203013062 GO:0042605 peptide antigen binding 3/755 45/18639 0.0666666666666667 1.64582781456954 0.274381404877851 0.728801038171254 GO:0140303 intramembrane lipid transporter activity 3/755 45/18639 0.0666666666666667 1.64582781456954 0.274381404877851 0.728801038171254 GO:0016758 hexosyltransferase activity 10/755 197/18639 0.050761421319797 1.25316838672807 0.277503181790329 0.731694411624256 GO:0008235 metalloexopeptidase activity 4/755 66/18639 0.0606060606060606 1.49620710415412 0.278377619441508 0.731694411624256 GO:0004529 DNA exonuclease activity 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0005160 transforming growth factor beta receptor binding 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0005227 calcium-activated cation channel activity 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0008198 ferrous iron binding 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0019865 immunoglobulin binding 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0034237 protein kinase A regulatory subunit binding 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0070006 metalloaminopeptidase activity 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0097602 cullin family protein binding 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0120014 phospholipid transfer activity 2/755 26/18639 0.0769230769230769 1.89903209373408 0.284153169562818 0.731694411624256 GO:0004180 carboxypeptidase activity 3/755 46/18639 0.0652173913043478 1.61004894903542 0.285510979624206 0.733154232996229 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/755 67/18639 0.0597014925373134 1.47387565483839 0.287495049821745 0.734503722713315 GO:0016757 glycosyltransferase activity 13/755 267/18639 0.048689138576779 1.2020090780564 0.287621198861848 0.734503722713315 GO:0030145 manganese ion binding 4/755 68/18639 0.0588235294117647 1.45220101285547 0.2966538941977 0.747332900367274 GO:0005504 fatty acid binding 3/755 47/18639 0.0638297872340425 1.57579258841764 0.296675843942995 0.747332900367274 GO:0061749 forked DNA-dependent helicase activity 3/755 47/18639 0.0638297872340425 1.57579258841764 0.296675843942995 0.747332900367274 GO:0099095 ligand-gated monoatomic anion channel activity 3/755 47/18639 0.0638297872340425 1.57579258841764 0.296675843942995 0.747332900367274 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/755 47/18639 0.0638297872340425 1.57579258841764 0.296675843942995 0.747332900367274 GO:0008266 poly(U) RNA binding 2/755 27/18639 0.0740740740740741 1.82869757174393 0.299337355683711 0.751993844766395 GO:0009378 four-way junction helicase activity 3/755 48/18639 0.0625 1.54296357615894 0.307865262849596 0.767180372746172 GO:0036121 double-stranded DNA helicase activity 3/755 48/18639 0.0625 1.54296357615894 0.307865262849596 0.767180372746172 GO:0043138 3'-5' DNA helicase activity 3/755 48/18639 0.0625 1.54296357615894 0.307865262849596 0.767180372746172 GO:0046966 nuclear thyroid hormone receptor binding 2/755 28/18639 0.0714285714285714 1.76338694418165 0.314467603038997 0.773629851431247 GO:0016417 S-acyltransferase activity 2/755 29/18639 0.0689655172413793 1.70258049783055 0.329523388055783 0.773629851431247 GO:0000287 magnesium ion binding 11/755 230/18639 0.0478260869565217 1.18070256262597 0.329807078615731 0.773629851431247 GO:0048020 CCR chemokine receptor binding 3/755 50/18639 0.06 1.48124503311258 0.330276776686236 0.773629851431247 GO:0030295 protein kinase activator activity 7/755 139/18639 0.0503597122302158 1.2432512268331 0.333063272224591 0.773629851431247 GO:0070851 growth factor receptor binding 7/755 139/18639 0.0503597122302158 1.2432512268331 0.333063272224591 0.773629851431247 GO:0001094 TFIID-class transcription factor complex binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0004955 prostaglandin receptor activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0008140 cAMP response element binding protein binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0008190 eukaryotic initiation factor 4E binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0008239 dipeptidyl-peptidase activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0016868 intramolecular phosphotransferase activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0031996 thioesterase binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0032356 oxidized DNA binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0035374 chondroitin sulfate binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0043208 glycosphingolipid binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0043422 protein kinase B binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0047429 nucleoside triphosphate diphosphatase activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0051880 G-quadruplex DNA binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0140135 mechanosensitive monoatomic cation channel activity 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:1990763 arrestin family protein binding 1/755 10/18639 0.1 2.4687417218543 0.338733915788378 0.773629851431247 GO:0004713 protein tyrosine kinase activity 7/755 140/18639 0.05 1.23437086092715 0.339654935460073 0.773629851431247 GO:0008187 poly-pyrimidine tract binding 2/755 30/18639 0.0666666666666667 1.64582781456954 0.344485933995557 0.773629851431247 GO:0022839 monoatomic ion-gated channel activity 2/755 30/18639 0.0666666666666667 1.64582781456954 0.344485933995557 0.773629851431247 GO:0033612 receptor serine/threonine kinase binding 2/755 30/18639 0.0666666666666667 1.64582781456954 0.344485933995557 0.773629851431247 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/755 30/18639 0.0666666666666667 1.64582781456954 0.344485933995557 0.773629851431247 GO:0048019 receptor antagonist activity 2/755 30/18639 0.0666666666666667 1.64582781456954 0.344485933995557 0.773629851431247 GO:0070566 adenylyltransferase activity 2/755 30/18639 0.0666666666666667 1.64582781456954 0.344485933995557 0.773629851431247 GO:0031406 carboxylic acid binding 9/755 187/18639 0.0481283422459893 1.18816446506357 0.346738231607605 0.773629851431247 GO:0003678 DNA helicase activity 4/755 74/18639 0.0540540540540541 1.33445498478611 0.352139546617825 0.773629851431247 GO:0031491 nucleosome binding 4/755 74/18639 0.0540540540540541 1.33445498478611 0.352139546617825 0.773629851431247 GO:0043177 organic acid binding 9/755 189/18639 0.0476190476190476 1.1755912961211 0.35822135717855 0.773629851431247 GO:0070273 phosphatidylinositol-4-phosphate binding 2/755 31/18639 0.0645161290322581 1.59273659474471 0.359338103429735 0.773629851431247 GO:0017046 peptide hormone binding 3/755 53/18639 0.0566037735849057 1.39740097463451 0.363832367711558 0.773629851431247 GO:0005543 phospholipid binding 22/755 497/18639 0.0442655935613682 1.09280317667595 0.364847207123755 0.773629851431247 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0004954 prostanoid receptor activity 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0005536 D-glucose binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0008199 ferric iron binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0008432 JUN kinase binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0008503 benzodiazepine receptor activity 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0008526 phosphatidylinositol transfer activity 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0019215 intermediate filament binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0032794 GTPase activating protein binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0034056 estrogen response element binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0034713 type I transforming growth factor beta receptor binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0042608 T cell receptor binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0045294 alpha-catenin binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0048185 activin binding 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0097493 structural molecule activity conferring elasticity 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0180030 inositol phosphate kinase activity 1/755 11/18639 0.0909090909090909 2.24431065623119 0.365533845660071 0.773629851431247 GO:0031369 translation initiation factor binding 2/755 32/18639 0.0625 1.54296357615894 0.374064296541417 0.775710278381256 GO:0017069 snRNA binding 3/755 54/18639 0.0555555555555556 1.37152317880795 0.374965639471915 0.775710278381256 GO:0050661 NADP binding 3/755 54/18639 0.0555555555555556 1.37152317880795 0.374965639471915 0.775710278381256 GO:0140463 chromatin-protein adaptor activity 3/755 54/18639 0.0555555555555556 1.37152317880795 0.374965639471915 0.775710278381256 GO:0004175 endopeptidase activity 18/755 405/18639 0.0444444444444444 1.09721854304636 0.377017638187624 0.775710278381256 GO:0008374 O-acyltransferase activity 3/755 55/18639 0.0545454545454545 1.34658639373871 0.386059305068996 0.775710278381256 GO:0000340 RNA 7-methylguanosine cap binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0005025 transforming growth factor beta receptor activity, type I 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0005026 transforming growth factor beta receptor activity, type II 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0005095 GTPase inhibitor activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0005165 neurotrophin receptor binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0005247 voltage-gated chloride channel activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0008179 adenylate cyclase binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0008603 cAMP-dependent protein kinase regulator activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0016208 AMP binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0016361 activin receptor activity, type I 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0016362 activin receptor activity, type II 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0017002 activin receptor activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0035259 nuclear glucocorticoid receptor binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0035497 cAMP response element binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0045295 gamma-catenin binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0097371 MDM2/MDM4 family protein binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0097677 STAT family protein binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:1990459 transferrin receptor binding 1/755 12/18639 0.0833333333333333 2.05728476821192 0.391249002763713 0.775710278381256 GO:0016835 carbon-oxygen lyase activity 4/755 79/18639 0.0506329113924051 1.24999580853383 0.398459632940935 0.775710278381256 GO:0033293 monocarboxylic acid binding 4/755 79/18639 0.0506329113924051 1.24999580853383 0.398459632940935 0.775710278381256 GO:0015020 glucuronosyltransferase activity 2/755 34/18639 0.0588235294117647 1.45220101285547 0.40308347083957 0.775710278381256 GO:0004722 protein serine/threonine phosphatase activity 5/755 103/18639 0.0485436893203883 1.19841831157976 0.40550353442461 0.775710278381256 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0005035 death receptor activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0005172 vascular endothelial growth factor receptor binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0005542 folic acid binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0008253 5'-nucleotidase activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0008417 fucosyltransferase activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0017154 semaphorin receptor activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0019104 DNA N-glycosylase activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0019855 calcium channel inhibitor activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0031432 titin binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0039706 co-receptor binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0043560 insulin receptor substrate binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0045159 myosin II binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0070123 transforming growth factor beta receptor activity, type III 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0070700 BMP receptor binding 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0140333 glycerophospholipid flippase activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0140666 annealing activity 1/755 13/18639 0.0769230769230769 1.89903209373408 0.415923239243737 0.775710278381256 GO:0033192 calmodulin-dependent protein phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0140791 histone H2AXS140 phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/755 81/18639 0.0493827160493827 1.21913171449595 0.416854018163752 0.775710278381256 GO:0000175 3'-5'-RNA exonuclease activity 2/755 35/18639 0.0571428571428571 1.41070955534532 0.417352100940552 0.775710278381256 GO:0043015 gamma-tubulin binding 2/755 35/18639 0.0571428571428571 1.41070955534532 0.417352100940552 0.775710278381256 GO:0140566 histone reader activity 2/755 35/18639 0.0571428571428571 1.41070955534532 0.417352100940552 0.775710278381256 GO:0042393 histone binding 11/755 247/18639 0.0445344129554656 1.09943963321447 0.417561411987321 0.775710278381256 GO:0017116 single-stranded DNA helicase activity 3/755 58/18639 0.0517241379310345 1.27693537337292 0.419028459017334 0.776878763018138 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/755 82/18639 0.0487804878048781 1.20426425456308 0.426004304570694 0.780666544613254 GO:0033549 MAP kinase phosphatase activity 4/755 82/18639 0.0487804878048781 1.20426425456308 0.426004304570694 0.780666544613254 GO:0008013 beta-catenin binding 5/755 106/18639 0.0471698113207547 1.16450081219543 0.429643665775288 0.780666544613254 GO:0070063 RNA polymerase binding 3/755 59/18639 0.0508474576271186 1.25529240094287 0.42989135975868 0.780666544613254 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/755 36/18639 0.0555555555555556 1.37152317880795 0.431445885417076 0.780666544613254 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/755 130/18639 0.0461538461538462 1.13941925624045 0.431662798233934 0.780666544613254 GO:0001540 amyloid-beta binding 4/755 83/18639 0.0481927710843374 1.18975504667677 0.435117696549077 0.780666544613254 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/755 83/18639 0.0481927710843374 1.18975504667677 0.435117696549077 0.780666544613254 GO:0030165 PDZ domain binding 4/755 83/18639 0.0481927710843374 1.18975504667677 0.435117696549077 0.780666544613254 GO:0004065 arylsulfatase activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0004705 JUN kinase activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0008195 phosphatidate phosphatase activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0016530 metallochaperone activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0019992 diacylglycerol binding 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0031404 chloride ion binding 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0034236 protein kinase A catalytic subunit binding 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0042043 neurexin family protein binding 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0046030 inositol trisphosphate phosphatase activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0098821 BMP receptor activity 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0098847 sequence-specific single stranded DNA binding 1/755 14/18639 0.0714285714285714 1.76338694418165 0.439598636772512 0.780666544613254 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/755 60/18639 0.05 1.23437086092715 0.440680327211503 0.781091134464748 GO:0017018 myosin phosphatase activity 4/755 84/18639 0.0476190476190476 1.1755912961211 0.444190171332526 0.784920404304023 GO:0019213 deacetylase activity 2/755 37/18639 0.0540540540540541 1.33445498478611 0.445355571112338 0.784920404304023 GO:0005179 hormone activity 6/755 132/18639 0.0454545454545455 1.12215532811559 0.446091502075824 0.784920404304023 GO:0019905 syntaxin binding 3/755 61/18639 0.0491803278688525 1.2141352730431 0.451389577520888 0.784920404304023 GO:0005109 frizzled binding 2/755 38/18639 0.0526315789473684 1.29933774834437 0.459072939106021 0.784920404304023 GO:0005501 retinoid binding 2/755 38/18639 0.0526315789473684 1.29933774834437 0.459072939106021 0.784920404304023 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/755 38/18639 0.0526315789473684 1.29933774834437 0.459072939106021 0.784920404304023 GO:0019840 isoprenoid binding 2/755 38/18639 0.0526315789473684 1.29933774834437 0.459072939106021 0.784920404304023 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/755 86/18639 0.0465116279069767 1.14825196365316 0.46219705633505 0.784920404304023 GO:0004559 alpha-mannosidase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0004953 icosanoid receptor activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0008242 omega peptidase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0008252 nucleotidase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0016846 carbon-sulfur lyase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0017081 chloride channel regulator activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0030553 cGMP binding 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0051371 muscle alpha-actinin binding 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0061578 K63-linked deubiquitinase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0120283 protein serine/threonine kinase binding 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0140776 protein-containing complex destabilizing activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0141050 histone H3K deacetylase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0141051 histone H4K deacetylase activity 1/755 15/18639 0.0666666666666667 1.64582781456954 0.462315577939587 0.784920404304023 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/755 39/18639 0.0512820512820513 1.26602139582272 0.472590736304003 0.800056341506985 GO:0004536 DNA nuclease activity 3/755 64/18639 0.046875 1.15722268211921 0.482986282284433 0.800056341506985 GO:0000062 fatty-acyl-CoA binding 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0004707 MAP kinase activity 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0015923 mannosidase activity 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0017070 U6 snRNA binding 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0034450 ubiquitin-ubiquitin ligase activity 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0140327 flippase activity 1/755 16/18639 0.0625 1.54296357615894 0.484112814766026 0.800056341506985 GO:0004177 aminopeptidase activity 2/755 40/18639 0.05 1.23437086092715 0.485902610861308 0.800056341506985 GO:0004532 RNA exonuclease activity 2/755 40/18639 0.05 1.23437086092715 0.485902610861308 0.800056341506985 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/755 40/18639 0.05 1.23437086092715 0.485902610861308 0.800056341506985 GO:0030331 nuclear estrogen receptor binding 2/755 40/18639 0.05 1.23437086092715 0.485902610861308 0.800056341506985 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/755 40/18639 0.05 1.23437086092715 0.485902610861308 0.800056341506985 GO:0071855 neuropeptide receptor binding 2/755 40/18639 0.05 1.23437086092715 0.485902610861308 0.800056341506985 GO:0003727 single-stranded RNA binding 4/755 89/18639 0.0449438202247191 1.10954684128283 0.488808853326742 0.803414551478527 GO:0038024 cargo receptor activity 3/755 65/18639 0.0461538461538462 1.13941925624045 0.493325559691447 0.807173318006828 GO:0160215 deacylase activity 3/755 65/18639 0.0461538461538462 1.13941925624045 0.493325559691447 0.807173318006828 GO:0042169 SH2 domain binding 2/755 41/18639 0.0487804878048781 1.20426425456308 0.499003051240631 0.807173318006828 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/755 41/18639 0.0487804878048781 1.20426425456308 0.499003051240631 0.807173318006828 GO:0004659 prenyltransferase activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0005092 GDP-dissociation inhibitor activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0008429 phosphatidylethanolamine binding 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0008484 sulfuric ester hydrolase activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0016805 dipeptidase activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0017110 nucleoside diphosphate phosphatase activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0032183 SUMO binding 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0036041 long-chain fatty acid binding 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0045125 bioactive lipid receptor activity 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:1901567 fatty acid derivative binding 1/755 17/18639 0.0588235294117647 1.45220101285547 0.505027534459504 0.807173318006828 GO:0035198 miRNA binding 2/755 42/18639 0.0476190476190476 1.1755912961211 0.511887328718491 0.815325693680483 GO:0048487 beta-tubulin binding 2/755 42/18639 0.0476190476190476 1.1755912961211 0.511887328718491 0.815325693680483 GO:0051219 phosphoprotein binding 4/755 93/18639 0.043010752688172 1.06182439649648 0.523413828970864 0.823626830248835 GO:0000400 four-way junction DNA binding 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0008525 phosphatidylcholine transporter activity 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0017075 syntaxin-1 binding 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0031690 adrenergic receptor binding 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0034185 apolipoprotein binding 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0050811 GABA receptor binding 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:1990381 ubiquitin-specific protease binding 1/755 18/18639 0.0555555555555556 1.37152317880795 0.525095422521102 0.823626830248835 GO:0002039 p53 binding 3/755 69/18639 0.0434782608695652 1.07336596602361 0.533608943662884 0.835566707391037 GO:0016790 thiolester hydrolase activity 2/755 44/18639 0.0454545454545455 1.12215532811559 0.536992071894236 0.838227774931385 GO:0003712 transcription coregulator activity 20/755 495/18639 0.0404040404040404 0.997471402769416 0.537404936732565 0.838227774931385 GO:0008381 mechanosensitive monoatomic ion channel activity 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0015245 fatty acid transmembrane transporter activity 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0016918 retinal binding 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0030506 ankyrin binding 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0042577 lipid phosphatase activity 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0046624 sphingolipid transporter activity 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0120227 acyl-CoA binding 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:1990380 K48-linked deubiquitinase activity 1/755 19/18639 0.0526315789473684 1.29933774834437 0.544350723310349 0.838227774931385 GO:0015108 chloride transmembrane transporter activity 5/755 121/18639 0.0413223140495868 1.02014120737781 0.545867735026985 0.839169801608649 GO:0046915 transition metal ion transmembrane transporter activity 2/755 45/18639 0.0444444444444444 1.09721854304636 0.549206521522906 0.842904711012804 GO:0015085 calcium ion transmembrane transporter activity 6/755 147/18639 0.0408163265306122 1.00764968238951 0.550774934973136 0.843914652429913 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/755 122/18639 0.040983606557377 1.01177939420258 0.553232638088553 0.846281609749321 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/755 46/18639 0.0434782608695652 1.07336596602361 0.561192682518302 0.846980484422543 GO:0042379 chemokine receptor binding 3/755 72/18639 0.0416666666666667 1.02864238410596 0.562601852676158 0.846980484422543 GO:0000339 RNA cap binding 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0001972 retinoic acid binding 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0016004 phospholipase activator activity 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0030627 pre-mRNA 5'-splice site binding 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0030742 GTP-dependent protein binding 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0052745 inositol phosphate phosphatase activity 1/755 20/18639 0.05 1.23437086092715 0.562826298170751 0.846980484422543 GO:0008509 monoatomic anion transmembrane transporter activity 6/755 149/18639 0.0402684563758389 0.994124183297035 0.564077081412399 0.847486960241968 GO:0043539 protein serine/threonine kinase activator activity 3/755 73/18639 0.0410958904109589 1.01455139254286 0.57201946615741 0.858029199236114 GO:0140359 ABC-type transporter activity 2/755 47/18639 0.0425531914893617 1.05052839227843 0.572948986454982 0.858035073414811 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0005248 voltage-gated sodium channel activity 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0008373 sialyltransferase activity 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0019200 carbohydrate kinase activity 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0035613 RNA stem-loop binding 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0051428 peptide hormone receptor binding 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0070182 DNA polymerase binding 1/755 21/18639 0.0476190476190476 1.1755912961211 0.580553681213937 0.859449002860071 GO:0003684 damaged DNA binding 3/755 74/18639 0.0405405405405405 1.00084123858958 0.581310166983026 0.859449002860071 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/755 48/18639 0.0416666666666667 1.02864238410596 0.584474365742172 0.861379550147844 GO:0140693 molecular condensate scaffold activity 2/755 48/18639 0.0416666666666667 1.02864238410596 0.584474365742172 0.861379550147844 GO:0004674 protein serine/threonine kinase activity 17/755 433/18639 0.0392609699769053 0.969251946224554 0.587865147443467 0.865001574095387 GO:0003774 cytoskeletal motor activity 6/755 153/18639 0.0392156862745098 0.968134008570316 0.59010019944548 0.866887361749746 GO:0016763 pentosyltransferase activity 2/755 49/18639 0.0408163265306122 1.00764968238951 0.595768215723112 0.866887361749746 GO:0031490 chromatin DNA binding 5/755 128/18639 0.0390625 0.964352235099338 0.596136817060949 0.866887361749746 GO:0004407 histone deacetylase activity 1/755 22/18639 0.0454545454545455 1.12215532811559 0.597563132856621 0.866887361749746 GO:0033558 protein lysine deacetylase activity 1/755 22/18639 0.0454545454545455 1.12215532811559 0.597563132856621 0.866887361749746 GO:0033691 sialic acid binding 1/755 22/18639 0.0454545454545455 1.12215532811559 0.597563132856621 0.866887361749746 GO:0034062 5'-3' RNA polymerase activity 1/755 22/18639 0.0454545454545455 1.12215532811559 0.597563132856621 0.866887361749746 GO:0097747 RNA polymerase activity 1/755 22/18639 0.0454545454545455 1.12215532811559 0.597563132856621 0.866887361749746 GO:0140517 protein-RNA adaptor activity 1/755 22/18639 0.0454545454545455 1.12215532811559 0.597563132856621 0.866887361749746 GO:0005006 epidermal growth factor receptor activity 2/755 50/18639 0.04 0.987496688741722 0.606830359016315 0.873632584110407 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0005158 insulin receptor binding 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0005212 structural constituent of eye lens 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0008171 O-methyltransferase activity 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0042171 lysophosphatidic acid acyltransferase activity 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0043274 phospholipase binding 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0071617 lysophospholipid acyltransferase activity 1/755 23/18639 0.0434782608695652 1.07336596602361 0.613883691200782 0.873632584110407 GO:0004518 nuclease activity 8/755 209/18639 0.0382775119617225 0.944972907886815 0.614995961449089 0.873632584110407 GO:0005010 insulin-like growth factor receptor activity 2/755 51/18639 0.0392156862745098 0.968134008570316 0.617661011979697 0.873632584110407 GO:0016597 amino acid binding 2/755 51/18639 0.0392156862745098 0.968134008570316 0.617661011979697 0.873632584110407 GO:0030544 Hsp70 protein binding 2/755 51/18639 0.0392156862745098 0.968134008570316 0.617661011979697 0.873632584110407 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/755 132/18639 0.0378787878787879 0.935129440096327 0.623420554840166 0.873632584110407 GO:0000149 SNARE binding 4/755 106/18639 0.0377358490566038 0.931600649756341 0.627191417312073 0.873632584110407 GO:0030159 signaling receptor complex adaptor activity 2/755 52/18639 0.0384615384615385 0.94951604686704 0.62826075318445 0.873632584110407 GO:0005261 monoatomic cation channel activity 13/755 341/18639 0.0381231671554252 0.941162533258239 0.628352347381306 0.873632584110407 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0004622 lysophospholipase activity 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0005315 phosphate transmembrane transporter activity 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0015295 solute:proton symporter activity 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0019957 C-C chemokine binding 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0035035 histone acetyltransferase binding 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0050699 WW domain binding 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0060229 lipase activator activity 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0070840 dynein complex binding 1/755 24/18639 0.0416666666666667 1.02864238410596 0.629543221343853 0.873632584110407 GO:0000049 tRNA binding 3/755 80/18639 0.0375 0.925778145695364 0.634303111625188 0.878922248843871 GO:0008234 cysteine-type peptidase activity 7/755 187/18639 0.0374331550802139 0.924127917271665 0.637439788420779 0.880967957953081 GO:0016860 intramolecular oxidoreductase activity 2/755 53/18639 0.0377358490566038 0.931600649756341 0.63863049379123 0.880967957953081 GO:0140296 general transcription initiation factor binding 2/755 53/18639 0.0377358490566038 0.931600649756341 0.63863049379123 0.880967957953081 GO:0005216 monoatomic ion channel activity 17/755 448/18639 0.0379464285714286 0.9367993140965 0.643976056315308 0.882592267245093 GO:0001848 complement binding 1/755 25/18639 0.04 0.987496688741722 0.644568462702187 0.882592267245093 GO:0003707 nuclear steroid receptor activity 1/755 25/18639 0.04 0.987496688741722 0.644568462702187 0.882592267245093 GO:0017056 structural constituent of nuclear pore 1/755 25/18639 0.04 0.987496688741722 0.644568462702187 0.882592267245093 GO:0047617 fatty acyl-CoA hydrolase activity 1/755 25/18639 0.04 0.987496688741722 0.644568462702187 0.882592267245093 GO:0051287 NAD binding 2/755 54/18639 0.037037037037037 0.914348785871965 0.648771449726588 0.885520437630579 GO:0016779 nucleotidyltransferase activity 5/755 136/18639 0.0367647058823529 0.907625633034671 0.64957270505803 0.885520437630579 GO:0140789 histone phosphatase activity 5/755 136/18639 0.0367647058823529 0.907625633034671 0.64957270505803 0.885520437630579 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/755 26/18639 0.0384615384615385 0.94951604686704 0.658985074427762 0.8904944081553 GO:0005112 Notch binding 1/755 26/18639 0.0384615384615385 0.94951604686704 0.658985074427762 0.8904944081553 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/755 26/18639 0.0384615384615385 0.94951604686704 0.658985074427762 0.8904944081553 GO:0008157 protein phosphatase 1 binding 1/755 26/18639 0.0384615384615385 0.94951604686704 0.658985074427762 0.8904944081553 GO:0016289 acyl-CoA hydrolase activity 1/755 26/18639 0.0384615384615385 0.94951604686704 0.658985074427762 0.8904944081553 GO:0043548 phosphatidylinositol 3-kinase binding 1/755 26/18639 0.0384615384615385 0.94951604686704 0.658985074427762 0.8904944081553 GO:0015103 inorganic anion transmembrane transporter activity 6/755 165/18639 0.0363636363636364 0.897724262492474 0.662954074552656 0.893373948868687 GO:1902936 phosphatidylinositol bisphosphate binding 4/755 111/18639 0.036036036036036 0.889636656524074 0.663043448567052 0.893373948868687 GO:0170055 lipid transmembrane transporter activity 2/755 56/18639 0.0357142857142857 0.881693472090823 0.668373240008511 0.896123546592267 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0005044 scavenger receptor activity 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0005385 zinc ion transmembrane transporter activity 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0008320 protein transmembrane transporter activity 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/755 27/18639 0.037037037037037 0.914348785871965 0.672817678994841 0.896123546592267 GO:0016866 intramolecular transferase activity 1/755 28/18639 0.0357142857142857 0.881693472090823 0.686089904030243 0.907299261014835 GO:0045499 chemorepellent activity 1/755 28/18639 0.0357142857142857 0.881693472090823 0.686089904030243 0.907299261014835 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/755 28/18639 0.0357142857142857 0.881693472090823 0.686089904030243 0.907299261014835 GO:0020037 heme binding 5/755 142/18639 0.0352112676056338 0.869275254174051 0.686582991806742 0.907299261014835 GO:0008408 3'-5' exonuclease activity 2/755 58/18639 0.0344827586206897 0.851290248915277 0.687080993778224 0.907299261014835 GO:0061980 regulatory RNA binding 2/755 58/18639 0.0344827586206897 0.851290248915277 0.687080993778224 0.907299261014835 GO:0004879 nuclear receptor activity 2/755 59/18639 0.0338983050847458 0.836861600628578 0.696105191463121 0.912408788195036 GO:0045309 protein phosphorylated amino acid binding 2/755 59/18639 0.0338983050847458 0.836861600628578 0.696105191463121 0.912408788195036 GO:0070888 E-box binding 2/755 59/18639 0.0338983050847458 0.836861600628578 0.696105191463121 0.912408788195036 GO:0015631 tubulin binding 14/755 385/18639 0.0363636363636364 0.897724262492474 0.698366362027007 0.912408788195036 GO:0035250 UDP-galactosyltransferase activity 1/755 29/18639 0.0344827586206897 0.851290248915277 0.698824422457902 0.912408788195036 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/755 29/18639 0.0344827586206897 0.851290248915277 0.698824422457902 0.912408788195036 GO:0051861 glycolipid binding 1/755 29/18639 0.0344827586206897 0.851290248915277 0.698824422457902 0.912408788195036 GO:0106222 lncRNA binding 1/755 29/18639 0.0344827586206897 0.851290248915277 0.698824422457902 0.912408788195036 GO:0008194 UDP-glycosyltransferase activity 5/755 145/18639 0.0344827586206897 0.851290248915277 0.704064846086891 0.913922098445349 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/755 89/18639 0.0337078651685393 0.832160130962125 0.70467858917165 0.913922098445349 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/755 89/18639 0.0337078651685393 0.832160130962125 0.70467858917165 0.913922098445349 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/755 60/18639 0.0333333333333333 0.822913907284768 0.704912945402832 0.913922098445349 GO:0098531 ligand-modulated transcription factor activity 2/755 60/18639 0.0333333333333333 0.822913907284768 0.704912945402832 0.913922098445349 GO:0140030 modification-dependent protein binding 6/755 173/18639 0.0346820809248555 0.856211001799181 0.706744405658363 0.915016849225283 GO:0016769 transferase activity, transferring nitrogenous groups 1/755 30/18639 0.0333333333333333 0.822913907284768 0.711042991025569 0.91902187260314 GO:0140793 histone H2AXY142 phosphatase activity 3/755 90/18639 0.0333333333333333 0.822913907284768 0.711820608984956 0.91902187260314 GO:0016836 hydro-lyase activity 2/755 61/18639 0.0327868852459016 0.809423515362067 0.713506957873406 0.919446550269094 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 8/755 229/18639 0.0349344978165939 0.862442522918534 0.714133242927451 0.919446550269094 GO:0004721 phosphoprotein phosphatase activity 6/755 175/18639 0.0342857142857143 0.84642573320719 0.717065514367606 0.921941375615494 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/755 91/18639 0.032967032967033 0.813870897314606 0.718828820280079 0.922928416065974 GO:0005164 tumor necrosis factor receptor binding 1/755 31/18639 0.032258064516129 0.796368297372356 0.722766487278763 0.924144184424019 GO:0016411 acylglycerol O-acyltransferase activity 1/755 31/18639 0.032258064516129 0.796368297372356 0.722766487278763 0.924144184424019 GO:0047499 calcium-independent phospholipase A2 activity 1/755 31/18639 0.032258064516129 0.796368297372356 0.722766487278763 0.924144184424019 GO:0004540 RNA nuclease activity 4/755 121/18639 0.0330578512396694 0.816112965902249 0.7274699652455 0.928876939094461 GO:0008378 galactosyltransferase activity 1/755 32/18639 0.03125 0.77148178807947 0.734014945044484 0.930735670731904 GO:0022884 macromolecule transmembrane transporter activity 1/755 32/18639 0.03125 0.77148178807947 0.734014945044484 0.930735670731904 GO:0047498 calcium-dependent phospholipase A2 activity 1/755 32/18639 0.03125 0.77148178807947 0.734014945044484 0.930735670731904 GO:0046982 protein heterodimerization activity 13/755 369/18639 0.035230352303523 0.869746406073332 0.735541402746007 0.930735670731904 GO:0000510 H3-H4 histone complex chaperone activity 5/755 151/18639 0.033112582781457 0.817464146309372 0.736957909727311 0.930735670731904 GO:0140584 chromatin extrusion motor activity 5/755 151/18639 0.033112582781457 0.817464146309372 0.736957909727311 0.930735670731904 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/755 151/18639 0.033112582781457 0.817464146309372 0.736957909727311 0.930735670731904 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/755 151/18639 0.033112582781457 0.817464146309372 0.736957909727311 0.930735670731904 GO:0003730 mRNA 3'-UTR binding 9/755 262/18639 0.0343511450381679 0.848041049491937 0.738923369502808 0.93194824969946 GO:0015616 DNA translocase activity 5/755 152/18639 0.0328947368421053 0.812086092715232 0.742171786591094 0.932240170961984 GO:0046906 tetrapyrrole binding 5/755 152/18639 0.0328947368421053 0.812086092715232 0.742171786591094 0.932240170961984 GO:0140674 ATP-dependent histone chaperone activity 5/755 152/18639 0.0328947368421053 0.812086092715232 0.742171786591094 0.932240170961984 GO:0019239 deaminase activity 1/755 33/18639 0.0303030303030303 0.748103552077062 0.744807588484663 0.934285026421222 GO:0061775 cohesin loader activity 5/755 153/18639 0.0326797385620915 0.806778340475263 0.747309340210879 0.936156430237141 GO:0008175 tRNA methyltransferase activity 1/755 34/18639 0.0294117647058824 0.726100506427737 0.755162864776939 0.9383860263381 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/755 34/18639 0.0294117647058824 0.726100506427737 0.755162864776939 0.9383860263381 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/755 34/18639 0.0294117647058824 0.726100506427737 0.755162864776939 0.9383860263381 GO:0030332 cyclin binding 1/755 34/18639 0.0294117647058824 0.726100506427737 0.755162864776939 0.9383860263381 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/755 34/18639 0.0294117647058824 0.726100506427737 0.755162864776939 0.9383860263381 GO:0090482 vitamin transmembrane transporter activity 1/755 34/18639 0.0294117647058824 0.726100506427737 0.755162864776939 0.9383860263381 GO:0004386 helicase activity 5/755 155/18639 0.032258064516129 0.796368297372356 0.757356359551907 0.939851867877668 GO:0004519 endonuclease activity 4/755 127/18639 0.031496062992126 0.777556447828127 0.761466522567608 0.940644942663282 GO:0042826 histone deacetylase binding 4/755 127/18639 0.031496062992126 0.777556447828127 0.761466522567608 0.940644942663282 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/755 268/18639 0.0335820895522388 0.829055055846595 0.762301740173146 0.940644942663282 GO:0004725 protein tyrosine phosphatase activity 3/755 98/18639 0.0306122448979592 0.755737261792134 0.764215175123623 0.940644942663282 GO:1901981 phosphatidylinositol phosphate binding 6/755 185/18639 0.0324324324324324 0.800672990871666 0.764871207563662 0.940644942663282 GO:0004623 phospholipase A2 activity 1/755 35/18639 0.0285714285714286 0.705354777672658 0.765098475478009 0.940644942663282 GO:0061631 ubiquitin conjugating enzyme activity 1/755 35/18639 0.0285714285714286 0.705354777672658 0.765098475478009 0.940644942663282 GO:0140658 ATP-dependent chromatin remodeler activity 5/755 158/18639 0.0316455696202532 0.781247380333641 0.771860877733557 0.946468323179373 GO:0004190 aspartic-type endopeptidase activity 1/755 36/18639 0.0277777777777778 0.685761589403973 0.774631406622607 0.946468323179373 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/755 36/18639 0.0277777777777778 0.685761589403973 0.774631406622607 0.946468323179373 GO:0045505 dynein intermediate chain binding 1/755 36/18639 0.0277777777777778 0.685761589403973 0.774631406622607 0.946468323179373 GO:0030695 GTPase regulator activity 17/755 489/18639 0.0347648261758691 0.858253768333807 0.774940083379875 0.946468323179373 GO:0016798 hydrolase activity, acting on glycosyl bonds 4/755 130/18639 0.0307692307692308 0.759612837493632 0.77718614329583 0.947311992736205 GO:0060589 nucleoside-triphosphatase regulator activity 17/755 490/18639 0.0346938775510204 0.856502230031085 0.777674677963595 0.947311992736205 GO:0016791 phosphatase activity 9/755 273/18639 0.032967032967033 0.813870897314606 0.780628355615566 0.948514577941966 GO:0003689 DNA clamp loader activity 5/755 160/18639 0.03125 0.77148178807947 0.781157233407544 0.948514577941966 GO:0005262 calcium channel activity 4/755 131/18639 0.0305343511450382 0.753814266215055 0.782240713312526 0.948514577941966 GO:0022829 wide pore channel activity 1/755 37/18639 0.027027027027027 0.667227492393055 0.783777957609004 0.948514577941966 GO:0070001 aspartic-type peptidase activity 1/755 37/18639 0.027027027027027 0.667227492393055 0.783777957609004 0.948514577941966 GO:0035402 histone H3T11 kinase activity 8/755 247/18639 0.0323886639676113 0.799592460519613 0.787608403018846 0.951581264210568 GO:0140299 molecular sensor activity 2/755 71/18639 0.028169014084507 0.695420203339241 0.788365060316846 0.951581264210568 GO:0008083 growth factor activity 5/755 162/18639 0.0308641975308642 0.761957321559971 0.790158757708827 0.952429743895767 GO:0008017 microtubule binding 9/755 276/18639 0.0326086956521739 0.805024474517708 0.79112287249163 0.952429743895767 GO:0106310 protein serine kinase activity 12/755 361/18639 0.0332409972299169 0.820634367375392 0.797016814297257 0.958022966849644 GO:0001217 DNA-binding transcription repressor activity 9/755 278/18639 0.0323741007194245 0.799232931535566 0.797911870589073 0.958022966849644 GO:0140713 histone chaperone activity 5/755 164/18639 0.0304878048780488 0.752665159101922 0.798869205366531 0.958022966849644 GO:0000217 DNA secondary structure binding 1/755 39/18639 0.0256410256410256 0.63301069791136 0.800973848725576 0.959305888589934 GO:0061791 GTPase motor activity 1/755 40/18639 0.025 0.617185430463576 0.809052598414404 0.963693220101119 GO:1990606 membrane scission GTPase motor activity 1/755 40/18639 0.025 0.617185430463576 0.809052598414404 0.963693220101119 GO:0019003 GDP binding 2/755 75/18639 0.0266666666666667 0.658331125827815 0.813134065131794 0.963693220101119 GO:0001530 lipopolysaccharide binding 1/755 41/18639 0.024390243902439 0.602132127281538 0.816803837093748 0.963693220101119 GO:0001727 lipid kinase activity 1/755 41/18639 0.024390243902439 0.602132127281538 0.816803837093748 0.963693220101119 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/755 41/18639 0.024390243902439 0.602132127281538 0.816803837093748 0.963693220101119 GO:0140318 protein transporter activity 1/755 41/18639 0.024390243902439 0.602132127281538 0.816803837093748 0.963693220101119 GO:0035091 phosphatidylinositol binding 9/755 284/18639 0.0316901408450704 0.782347728756646 0.817295703191891 0.963693220101119 GO:0004620 phospholipase activity 3/755 109/18639 0.0275229357798165 0.679470198675497 0.823327431529942 0.963693220101119 GO:0004520 DNA endonuclease activity 1/755 42/18639 0.0238095238095238 0.587795648060549 0.824240825102901 0.963693220101119 GO:0019894 kinesin binding 1/755 42/18639 0.0238095238095238 0.587795648060549 0.824240825102901 0.963693220101119 GO:0003724 RNA helicase activity 2/755 77/18639 0.025974025974026 0.641231616066053 0.824521293921592 0.963693220101119 GO:0051540 metal cluster binding 2/755 77/18639 0.025974025974026 0.641231616066053 0.824521293921592 0.963693220101119 GO:0005245 voltage-gated calcium channel activity 1/755 43/18639 0.0232558139534884 0.574125981826582 0.831376286577725 0.963693220101119 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/755 43/18639 0.0232558139534884 0.574125981826582 0.831376286577725 0.963693220101119 GO:0008186 ATP-dependent activity, acting on RNA 2/755 79/18639 0.0253164556962025 0.624997904266913 0.835281086005208 0.963693220101119 GO:0003823 antigen binding 5/755 174/18639 0.028735632183908 0.709408540762731 0.838211088432829 0.963693220101119 GO:0003714 transcription corepressor activity 6/755 204/18639 0.0294117647058824 0.726100506427737 0.83873313703121 0.963693220101119 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/755 45/18639 0.0222222222222222 0.548609271523179 0.844790974504847 0.963693220101119 GO:0008009 chemokine activity 1/755 45/18639 0.0222222222222222 0.548609271523179 0.844790974504847 0.963693220101119 GO:0035401 histone H3Y41 kinase activity 3/755 115/18639 0.0260869565217391 0.644019579614166 0.849893780505832 0.963693220101119 GO:0101005 deubiquitinase activity 3/755 115/18639 0.0260869565217391 0.644019579614166 0.849893780505832 0.963693220101119 GO:0140801 histone H2AXY142 kinase activity 3/755 115/18639 0.0260869565217391 0.644019579614166 0.849893780505832 0.963693220101119 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/755 46/18639 0.0217391304347826 0.536682983011805 0.851093158771214 0.963693220101119 GO:0140938 histone H3 methyltransferase activity 1/755 47/18639 0.0212765957446809 0.525264196139214 0.857139771212872 0.963693220101119 GO:0008094 ATP-dependent activity, acting on DNA 6/755 210/18639 0.0285714285714286 0.705354777672658 0.857749214532901 0.963693220101119 GO:0004527 exonuclease activity 2/755 84/18639 0.0238095238095238 0.587795648060549 0.859616246988753 0.963693220101119 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/755 48/18639 0.0208333333333333 0.51432119205298 0.862941162818631 0.963693220101119 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/755 243/18639 0.0288065843621399 0.711160166789306 0.866603524201437 0.963693220101119 GO:0005004 GPI-linked ephrin receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0005008 hepatocyte growth factor receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0005009 insulin receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0005011 macrophage colony-stimulating factor receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0005020 stem cell factor receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0008288 boss receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0036332 placental growth factor receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0038062 protein tyrosine kinase collagen receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0060175 brain-derived neurotrophic factor receptor activity 1/755 49/18639 0.0204081632653061 0.503824841194756 0.868507265883121 0.963693220101119 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0004711 ribosomal protein S6 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0035175 histone H3S10 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0035979 histone H2AXS139 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0044022 histone H3S28 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0044023 histone H4S1 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0044024 histone H2AS1 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0044025 histone H2BS14 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0072354 histone H3T3 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0072371 histone H2AS121 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0140823 histone H2BS36 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0140855 histone H3S57 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0140995 histone H2A kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0140997 histone H4 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0140998 histone H2B kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:1990244 histone H2AT120 kinase activity 7/755 245/18639 0.0285714285714286 0.705354777672658 0.871886778060354 0.963693220101119 GO:0008081 phosphoric diester hydrolase activity 2/755 87/18639 0.0229885057471264 0.567526832610185 0.872592816946271 0.963693220101119 GO:0005007 fibroblast growth factor receptor activity 1/755 50/18639 0.02 0.493748344370861 0.873847610921219 0.963693220101119 GO:0005017 platelet-derived growth factor receptor activity 1/755 50/18639 0.02 0.493748344370861 0.873847610921219 0.963693220101119 GO:0005019 platelet-derived growth factor beta-receptor activity 1/755 50/18639 0.02 0.493748344370861 0.873847610921219 0.963693220101119 GO:0032813 tumor necrosis factor receptor superfamily binding 1/755 50/18639 0.02 0.493748344370861 0.873847610921219 0.963693220101119 GO:0042578 phosphoric ester hydrolase activity 11/755 363/18639 0.0303030303030303 0.748103552077062 0.874020157143056 0.963693220101119 GO:0004677 DNA-dependent protein kinase activity 7/755 246/18639 0.0284552845528455 0.702487481828461 0.874463020638849 0.963693220101119 GO:0140857 histone H3T45 kinase activity 7/755 246/18639 0.0284552845528455 0.702487481828461 0.874463020638849 0.963693220101119 GO:0005506 iron ion binding 4/755 154/18639 0.025974025974026 0.641231616066053 0.875085026957961 0.963693220101119 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/755 122/18639 0.0245901639344262 0.60706763652155 0.876431588413081 0.963693220101119 GO:0035403 histone H3T6 kinase activity 7/755 247/18639 0.0283400809716599 0.699643402954661 0.876996280319432 0.963693220101119 GO:0140097 catalytic activity, acting on DNA 10/755 336/18639 0.0297619047619048 0.734744560075686 0.878182862761573 0.963693220101119 GO:0005021 vascular endothelial growth factor receptor activity 1/755 51/18639 0.0196078431372549 0.484067004285158 0.87897134290005 0.963693220101119 GO:0005030 neurotrophin receptor activity 1/755 51/18639 0.0196078431372549 0.484067004285158 0.87897134290005 0.963693220101119 GO:0005272 sodium channel activity 1/755 51/18639 0.0196078431372549 0.484067004285158 0.87897134290005 0.963693220101119 GO:0004679 AMP-activated protein kinase activity 7/755 248/18639 0.0282258064516129 0.696822260200812 0.879487016402963 0.963693220101119 GO:0005003 ephrin receptor activity 1/755 53/18639 0.0188679245283019 0.465800324878171 0.888603712643442 0.970242216278529 GO:0005005 transmembrane-ephrin receptor activity 1/755 53/18639 0.0188679245283019 0.465800324878171 0.888603712643442 0.970242216278529 GO:0038064 collagen receptor activity 1/755 53/18639 0.0188679245283019 0.465800324878171 0.888603712643442 0.970242216278529 GO:0052689 carboxylic ester hydrolase activity 2/755 92/18639 0.0217391304347826 0.536682983011805 0.891789687901582 0.972483371404951 GO:0019783 ubiquitin-like protein peptidase activity 3/755 127/18639 0.0236220472440945 0.583167335871096 0.892754421861503 0.972483371404951 GO:0008236 serine-type peptidase activity 5/755 194/18639 0.0257731958762887 0.636273639653171 0.898012601855633 0.977063006948558 GO:0016298 lipase activity 3/755 130/18639 0.0230769230769231 0.569709628120224 0.901594436432813 0.977937937505364 GO:0030170 pyridoxal phosphate binding 1/755 56/18639 0.0178571428571429 0.440846736045412 0.901635803226002 0.977937937505364 GO:0008276 protein methyltransferase activity 2/755 95/18639 0.0210526315789474 0.519735099337748 0.901981592844753 0.977937937505364 GO:0070279 vitamin B6 binding 1/755 57/18639 0.0175438596491228 0.433112582781457 0.90563219608853 0.980748885250079 GO:0017171 serine hydrolase activity 5/755 198/18639 0.0252525252525253 0.623419626730885 0.907358465450788 0.98147175901153 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/755 167/18639 0.0239520958083832 0.591315382480073 0.910657550144597 0.982378259567079 GO:0008170 N-methyltransferase activity 2/755 98/18639 0.0204081632653061 0.503824841194756 0.911272081686807 0.982378259567079 GO:0016829 lyase activity 5/755 200/18639 0.025 0.617185430463576 0.911744612869497 0.982378259567079 GO:0015459 potassium channel regulator activity 1/755 59/18639 0.0169491525423729 0.418430800314289 0.913145069712231 0.982378259567079 GO:0001098 basal transcription machinery binding 1/755 60/18639 0.0166666666666667 0.411456953642384 0.916674427751374 0.982378259567079 GO:0001099 basal RNA polymerase II transcription machinery binding 1/755 60/18639 0.0166666666666667 0.411456953642384 0.916674427751374 0.982378259567079 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/755 60/18639 0.0166666666666667 0.411456953642384 0.916674427751374 0.982378259567079 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/755 60/18639 0.0166666666666667 0.411456953642384 0.916674427751374 0.982378259567079 GO:0140767 enzyme-substrate adaptor activity 3/755 139/18639 0.0215827338129496 0.532821954357044 0.924303540284289 0.989410371643806 GO:0004843 cysteine-type deubiquitinase activity 2/755 108/18639 0.0185185185185185 0.457174392935982 0.936612906021741 0.999112688081389 GO:0008173 RNA methyltransferase activity 1/755 67/18639 0.0149253731343284 0.368468913709598 0.937678574574767 0.999112688081389 GO:0016500 protein-hormone receptor activity 1/755 67/18639 0.0149253731343284 0.368468913709598 0.937678574574767 0.999112688081389 GO:0042054 histone methyltransferase activity 1/755 67/18639 0.0149253731343284 0.368468913709598 0.937678574574767 0.999112688081389 GO:0003777 microtubule motor activity 1/755 68/18639 0.0147058823529412 0.363050253213868 0.940212102261394 0.999414813249049 GO:0140223 general transcription initiation factor activity 1/755 68/18639 0.0147058823529412 0.363050253213868 0.940212102261394 0.999414813249049 GO:0016755 aminoacyltransferase activity 14/755 496/18639 0.0282258064516129 0.696822260200812 0.942496771112299 0.999414813249049 GO:0016279 protein-lysine N-methyltransferase activity 1/755 69/18639 0.0144927536231884 0.357788655341204 0.94264276635017 0.999414813249049 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/755 70/18639 0.0142857142857143 0.352677388836329 0.944974737885206 0.999414813249049 GO:0016278 lysine N-methyltransferase activity 1/755 70/18639 0.0142857142857143 0.352677388836329 0.944974737885206 0.999414813249049 GO:0019842 vitamin binding 3/755 150/18639 0.02 0.493748344370861 0.945508944141765 0.999414813249049 GO:0004521 RNA endonuclease activity 1/755 73/18639 0.0136986301369863 0.338183797514288 0.951417714565775 0.999986401102072 GO:0141003 histone H2AX kinase activity 9/755 354/18639 0.0254237288135593 0.627646200471433 0.952443237787544 0.999986401102072 GO:0035064 methylated histone binding 1/755 74/18639 0.0135135135135135 0.333613746196528 0.953393348816709 0.999986401102072 GO:0140098 catalytic activity, acting on RNA 10/755 387/18639 0.0258397932816537 0.637917757585092 0.954237306241894 0.999986401102072 GO:0045182 translation regulator activity 9/755 356/18639 0.0252808988764045 0.624120098221594 0.954424666722221 0.999986401102072 GO:0140996 histone H3 kinase activity 9/755 357/18639 0.0252100840336134 0.622371862652346 0.95538763426875 0.999986401102072 GO:0051536 iron-sulfur cluster binding 1/755 76/18639 0.0131578947368421 0.324834437086093 0.957107156407655 0.999986401102072 GO:0140034 methylation-dependent protein binding 1/755 76/18639 0.0131578947368421 0.324834437086093 0.957107156407655 0.999986401102072 GO:0035173 histone kinase activity 9/755 360/18639 0.025 0.617185430463576 0.95816892614781 0.999986401102072 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/755 484/18639 0.0268595041322314 0.663091784795578 0.958574668861656 0.999986401102072 GO:0003697 single-stranded DNA binding 2/755 121/18639 0.0165289256198347 0.408056482951125 0.95942345460481 0.999986401102072 GO:0008528 G protein-coupled peptide receptor activity 2/755 122/18639 0.0163934426229508 0.404711757681034 0.960806652374672 0.999986401102072 GO:0001216 DNA-binding transcription activator activity 13/755 491/18639 0.0264765784114053 0.653638337761832 0.963745649141884 0.999986401102072 GO:0015101 organic cation transmembrane transporter activity 1/755 81/18639 0.0123456790123457 0.304782928623988 0.965149434477541 0.999986401102072 GO:0005096 GTPase activator activity 6/755 271/18639 0.022140221402214 0.546584883067374 0.965642690264616 0.999986401102072 GO:0008168 methyltransferase activity 4/755 204/18639 0.0196078431372549 0.484067004285158 0.967801031949364 0.999986401102072 GO:0001653 peptide receptor activity 2/755 128/18639 0.015625 0.385740894039735 0.968202336350656 0.999986401102072 GO:0005244 voltage-gated monoatomic ion channel activity 3/755 173/18639 0.0173410404624277 0.42810550089959 0.973258241148614 0.999986401102072 GO:0022832 voltage-gated channel activity 3/755 175/18639 0.0171428571428571 0.423212866603595 0.974898201739836 0.999986401102072 GO:0019787 ubiquitin-like protein transferase activity 12/755 479/18639 0.0250521920668058 0.61847391779231 0.975103203315642 0.999986401102072 GO:0004252 serine-type endopeptidase activity 3/755 176/18639 0.0170454545454545 0.420808248043347 0.975681938228711 0.999986401102072 GO:0099094 ligand-gated monoatomic cation channel activity 2/755 136/18639 0.0147058823529412 0.363050253213868 0.97600054027993 0.999986401102072 GO:0016741 transferase activity, transferring one-carbon groups 4/755 215/18639 0.0186046511627907 0.459300785461266 0.976605279749161 0.999986401102072 GO:0140101 catalytic activity, acting on a tRNA 2/755 139/18639 0.0143884892086331 0.355214636238029 0.978418813335306 0.999986401102072 GO:0051213 dioxygenase activity 1/755 93/18639 0.010752688172043 0.265456099124119 0.978831574420725 0.999986401102072 GO:0016410 N-acyltransferase activity 1/755 94/18639 0.0106382978723404 0.262632098069607 0.979693332282924 0.999986401102072 GO:0004896 cytokine receptor activity 1/755 96/18639 0.0104166666666667 0.25716059602649 0.981313159043858 0.999986401102072 GO:0016407 acetyltransferase activity 1/755 96/18639 0.0104166666666667 0.25716059602649 0.981313159043858 0.999986401102072 GO:0030594 neurotransmitter receptor activity 1/755 97/18639 0.0103092783505155 0.254509455861268 0.982074015697144 0.999986401102072 GO:0015276 ligand-gated monoatomic ion channel activity 3/755 186/18639 0.0161290322580645 0.398184148686178 0.982339798270709 0.999986401102072 GO:0022834 ligand-gated channel activity 3/755 188/18639 0.0159574468085106 0.39394814710441 0.983443731900735 0.999986401102072 GO:0004497 monooxygenase activity 1/755 106/18639 0.00943396226415094 0.232900162439085 0.987670020217533 0.999986401102072 GO:0140375 immune receptor activity 2/755 156/18639 0.0128205128205128 0.31650534895568 0.988254168906454 0.999986401102072 GO:0004842 ubiquitin-protein transferase activity 10/755 449/18639 0.022271714922049 0.549831118453075 0.988262694492257 0.999986401102072 GO:0061630 ubiquitin protein ligase activity 7/755 353/18639 0.0198300283286119 0.48955218280397 0.989893320456403 0.999986401102072 GO:0022836 gated channel activity 6/755 318/18639 0.0188679245283019 0.465800324878171 0.990044321036042 0.999986401102072 GO:0015294 solute:monoatomic cation symporter activity 1/755 116/18639 0.00862068965517241 0.212822562228819 0.99186627795929 0.999986401102072 GO:0061659 ubiquitin-like protein ligase activity 7/755 372/18639 0.0188172043010753 0.464548173467208 0.993902312941486 0.999986401102072 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/755 181/18639 0.0110497237569061 0.272789140536387 0.995280000887775 0.999986401102072 GO:0015297 antiporter activity 1/755 135/18639 0.00740740740740741 0.182869757174393 0.996312466244342 0.999986401102072 GO:0005125 cytokine activity 3/755 234/18639 0.0128205128205128 0.31650534895568 0.996412287894119 0.999986401102072 GO:0022843 voltage-gated monoatomic cation channel activity 1/755 143/18639 0.00699300699300699 0.172639281248553 0.997357748217234 0.999986401102072 GO:0015293 symporter activity 1/755 146/18639 0.00684931506849315 0.169091898757144 0.997668303402213 0.999986401102072 GO:0046873 metal ion transmembrane transporter activity 8/755 450/18639 0.0177777777777778 0.438887417218543 0.998039763175283 0.999986401102072 GO:0015081 sodium ion transmembrane transporter activity 1/755 164/18639 0.00609756097560976 0.150533031820384 0.998899297227921 0.999986401102072 GO:0046943 carboxylic acid transmembrane transporter activity 1/755 188/18639 0.00531914893617021 0.131316049034803 0.999595893461216 0.999986401102072 GO:0005342 organic acid transmembrane transporter activity 1/755 189/18639 0.00529100529100529 0.130621255124566 0.999612429174011 0.999986401102072 GO:0015291 secondary active transmembrane transporter activity 2/755 287/18639 0.00696864111498258 0.172037750651868 0.999914974560998 0.999986401102072 GO:0030371 translation repressor activity 2/755 329/18639 0.0060790273556231 0.150075484611204 0.999983461667098 0.999986401102072 GO:0008514 organic anion transmembrane transporter activity 1/755 269/18639 0.00371747211895911 0.0917747851990448 0.999986401102072 0.999986401102072