category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	15/81	268/9376	6.47871752349364	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/HSPA5/MT-ND4/MT-CO1/ERN1/DUSP1/UBC/GNAS/ATP5F1A	8.494508317079
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	14/81	275/9376	5.89288439955107	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/HSPA5/HSPA8/NCAM1/MT-ND4/MT-CO1/CAV1/ATP5F1A	7.68758968626756
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	10/81	138/9376	8.38790481302559	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/MT-ND4/MT-CO1/ATP5F1A	8.16159999862011
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	12/81	235/9376	5.91079590228526	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/MT-ND4/MT-CO1/ACTG1/GNAS/ATP5F1A	7.11692537509361
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	11/81	205/9376	6.21114122252334	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/MT-ND4/MT-CO1/COL1A2/ATP5F1A	7.04214360645856
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	14/81	368/9376	4.40365002683843	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/HSPA5/BCL2/MT-ND4/MT-CO1/ERN1/ACTG1/ATP5F1A	6.21810525940859
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	11/81	227/9376	5.60918039919508	MT-ND3/FOS/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/MT-ND4/MT-CO1/ATP5F1A	6.5622575579701
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	12/81	308/9376	4.50986050986051	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/MT-ND4/HIP1/MT-CO1/ERN1/ATP5F1A	5.84672826736892
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	15/81	480/9376	3.61728395061728	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/MT-ND1/MT-CYB/HSPA5/BCL2/MT-ND4/HIP1/MT-CO1/ERN1/UBC/ATP5F1A	5.49512434516564
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	8/81	142/9376	6.52130064336637	FOS/BCL2/ACTG1/CCL2/CAV1/DUSP1/HSP90AA1/HSP90AB1	6.18862380390936
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	9/81	216/9376	4.82304526748971	FOS/CD40LG/HSPA5/BCL2/HSPA8/ERN1/CCL2/HSP90AA1/HSP90AB1	5.30630280849533
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	12/81	388/9376	3.57999236349752	MT-ND3/MT-ND2/MT-CO2/MT-CO3/MT-ATP6/EIF2AK2/MT-ND1/MT-CYB/MT-ND4/MT-CO1/ERN1/ATP5F1A	4.84513856674556
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	7/81	139/9376	5.82929212185807	FOS/FKBP5/BCL2/HSPA8/GNAS/HSP90AA1/HSP90AB1	5.35462246090469
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/81	70/9376	8.26807760141093	CD40LG/HLA-C/ACTG1/CAV1/EIF4G3	5.69758092201617
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	5/81	82/9376	7.0581150255947	HSPA5/HSPA8/HLA-C/HSP90AA1/HSP90AB1	5.14335567392825
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	10/81	362/9376	3.19759907236887	CSH1/DDIT4/BCL2/CSH2/COL1A2/CCND3/GNG11/HSP90AA1/AREG/HSP90AB1	3.98058976569232
Human Diseases	Infectious disease: viral	hsa05162	Measles	6/81	136/9376	5.10675381263617	FOS/EIF2AK2/BCL2/HSPA8/MX1/CCND3	4.50334882368046
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/81	94/9376	6.15707906488048	FOS/FOSB/CCL2/HSP90AA1/HSP90AB1	4.6908374647421
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/81	157/9376	4.42368483132814	FOS/MT-CO2/MT-CO3/MT-CYB/MT-CO1/ERN1	4.03836108271485
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	6/81	168/9376	4.13403880070547	CSH1/BCL2/CSH2/IL12RB2/CCND3/CISH	3.82630693627838
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	6/81	174/9376	3.99148573861218	HSPA5/BCL2/HSPA8/ERN1/HSP90AA1/HSP90AB1	3.71812423592748
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	8/81	298/9376	3.10746540724169	CSH1/CCL4/CXCR4/CD40LG/CSH2/IL12RB2/CCL2/XCL2	3.45125419948007
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	6/81	180/9376	3.85843621399177	EIF2AK2/SP100/BCL2/HLA-C/BST2/CCL2	3.61467060370026
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	7/81	248/9376	3.26722421346077	FOS/BCL2/ANXA2/MYL12B/ACTG1/HSP90AA1/HSP90AB1	3.37781567228896
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	5/81	137/9376	4.22456519780121	FOS/BCL2/CTSW/ERN1/ACTG1	3.54913413295533
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/81	87/9376	5.32198098481623	MT-CO2/MT-CO3/MT-CYB/MT-CO1	3.78060624391681
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	6/81	196/9376	3.54346182917611	FOS/EIF2AK2/ZFP36/HLA-C/UBC/GNG11	3.35919619759525
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	6/81	203/9376	3.42127349023901	BCL2/MYL12B/ACTG1/CAV1/COL1A2/CCND3	3.25566431945466
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/81	204/9376	3.40450254175744	ACTG1/CAV1/LUM/COL1A2/TIMP3/DCN	3.24124419349647
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	6/81	205/9376	3.38789521228546	EIF2AK2/ISG15/BCL2/HLA-C/CCND3/VIM	3.22691331591786
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/81	50/9376	6.94518518518518	CD40LG/CCL2/KLRB1	3.93465025004985
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	5/81	149/9376	3.88433175905212	MT-ND3/MT-ND2/MT-ND1/MT-ND4/GNG11	3.3129244833302
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	6/81	214/9376	3.245413637937	FOS/CXCR4/BCL2/HLA-C/BST2/GNG11	3.10178398721267
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	4/81	100/9376	4.63012345679012	CCL4/CXCR4/CCL2/XCL2	3.40678303428981
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/81	217/9376	3.2005461682881	FOS/BCL2/CCND3/GNAS/HSP90AA1/HSP90AB1	3.06153883438391
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/81	54/9376	6.43072702331962	CD40LG/HLA-C/TG	3.73597322128642
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/81	227/9376	3.0595529450155	CCL4/CXCR4/HLA-C/CCL2/GNG11/GNAS	2.93226033891573
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/81	168/9376	3.44503233392122	EIF2AK2/BCL2/HSP90AA1/HSP90AB1/GLUL	2.98510796248017
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/81	173/9376	3.34546492542639	EIF2AK2/MX1/ACTG1/CCL2/CCND3	2.90663657393745
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	4/81	115/9376	4.02619431025228	FOS/BCL2/KCNQ5/GNG11	3.04803703135512
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/81	115/9376	4.02619431025228	FOS/BCL2/RUNX2/GNAS	3.04803703135512
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/81	122/9376	3.79518316130338	FOS/CSH1/CSH2/GNAS	2.90087416142185
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/81	69/9376	5.03274288781535	FOS/FOSB/GNAS	3.13851112875046
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	2/81	27/9376	8.57430269775949	FADS2/ELOVL6	3.67913234067832
Organismal Systems	Immune system	hsa04611	Platelet activation	4/81	126/9376	3.67470115618264	MYL12B/ACTG1/COL1A2/GNAS	2.82158489813964
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	7/81	333/9376	2.43324806287769	EIF2AK2/ISG15/MX1/HLA-C/COL1A2/CCND3/GNAS	2.48594013151502
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	3/81	73/9376	4.75697615423643	CXCR4/MX1/BST2	3.00809680750816
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	5/81	193/9376	2.9987846222734	CCL4/CXCR4/CCL2/XCL2/GNG11	2.61912250600548
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/81	130/9376	3.56163342830009	FOS/COL1A2/GNG11/GNAS	2.74546027521809
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/81	75/9376	4.63012345679012	HSPA5/TG/GNAS	2.94639287269473
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/81	76/9376	4.5692007797271	FADS2/UBC/FABP5	2.91635072434983
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/81	87/9376	3.99148573861218	FOS/BCL2/AREG	2.61676987976526
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/81	154/9376	3.00657367324034	FOS/ACTG1/MYL6/GNAS	2.3437234316453
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/81	39/9376	5.93605571383349	CD40LG/HLA-C	2.88344802598669
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/81	157/9376	2.94912322088543	ID2/ACTG1/CCND3/AREG	2.29906190213953
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/81	160/9376	2.89382716049383	CD40LG/NCAM1/HLA-C/SELPLG	2.25544660216859
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	3/81	97/9376	3.57999236349752	FOS/GNG11/GNAS	2.38427942378267
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/81	99/9376	3.50766928544706	FOS/BCL2/GNAS	2.34146424438787
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/81	238/9376	2.43178752982675	FOS/EIF2AK2/ISG15/MX1/CCL2	2.0885502457392
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/81	101/9376	3.43821048771544	BCL2/CCL2/COL1A2	2.29973806327589
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/81	169/9376	2.7397180217693	DDIT4/BCL2/ERN1/UBC	2.13042668687249
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/81	103/9376	3.37144911902193	FOS/CCL2/GNAS	2.25904948353947
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/81	105/9376	3.30723104056437	CCL4/CD40LG/BCL2	2.21935050053709
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/81	106/9376	3.27603074772886	BCL2/HSP90AA1/HSP90AB1	2.19985796336586
NA	NA	hsa03272	Virion - Hepatitis viruses	2/81	48/9376	4.82304526748971	CD9/DPP4	2.47878717770653
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/81	49/9376	4.72461577223482	FOSB/GNAS	2.44012447046008
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/81	109/9376	3.18586476384642	FOS/HSP90AA1/HSP90AB1	2.14274459037658
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/81	50/9376	4.63012345679012	CXCR4/CD40LG	2.4024930632209
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/81	51/9376	4.53933672234326	ACTG1/GNAS	2.3658434333522
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/81	112/9376	3.1005291005291	CD40LG/BCL2/HSPA8	2.08757405809738
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	3/81	115/9376	3.01964573268921	DUSP1/GNG11/GNAS	2.03422330238334
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	4/81	187/9376	2.47600184855087	BCL2/CCL2/HSP90AA1/HSP90AB1	1.90316757342375
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/81	116/9376	2.99361430395913	CXCR4/MYL12B/ACTG1	2.01682442771803
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	3/81	116/9376	2.99361430395913	GNG11/GNAS/GLUL	2.01682442771803
Cellular Processes	Cell motility	hsa04814	Motor proteins	4/81	194/9376	2.38666157566501	MYO1D/MYL12B/ACTG1/MYL6	1.82182288318901
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/81	57/9376	4.06151180420186	FADS2/ELOVL6	2.16417392840212
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/81	201/9376	2.30354400835329	RUNX2/ID2/DUSP6/ZBTB16	1.74391029140641
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/81	12/9376	9.64609053497942	NCAM1	2.79758409290219
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/81	205/9376	2.2585968081903	EIF2AK2/SP100/HLA-C/CCND3	1.70082119970158
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/81	133/9376	2.61097187412977	FOS/GNG11/GNAS	1.74666956420234
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/81	68/9376	3.40450254175744	DUSP6/ZBTB16	1.85761179563364
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/81	138/9376	2.51637144390768	FOS/ACTG1/CCL2	1.67517279766306
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	5/81	300/9376	1.92921810699588	FOS/HSPA8/DUSP6/DUSP1/AREG	1.5269840417034
NA	NA	hsa04081	Hormone signaling	4/81	219/9376	2.11421162410508	CSH1/CSH2/GNG11/GNAS	1.55745886789409
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/81	71/9376	3.26065032168319	FOS/CISH	1.78487508342564
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/81	224/9376	2.06701940035273	FOS/ZFP36/HLA-C/CCND3	1.50883506975001
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/81	75/9376	3.08674897119342	BCL2/CCND3	1.69371162413962
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/81	17/9376	6.80900508351489	GLUL	2.23776740747682
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/81	76/9376	3.0461338531514	ACTG1/GNAS	1.6718711871432
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/81	233/9376	1.98717744926615	ACTG1/COL1A2/VIM/DCN	1.42440102377237
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/81	78/9376	2.96802785691675	ACTG1/CAV1	1.62924809725573
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	3/81	154/9376	2.25493025493026	BCL2/CREM/GNAS	1.46578691965543
NA	NA	hsa04518	Integrin signaling	3/81	154/9376	2.25493025493026	ACTG1/COL1A2/CCND3	1.46578691965543
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/81	157/9376	2.21184241566407	HLA-C/CCND3/ZFP36L2	1.42941231185187
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/81	250/9376	1.85204938271605	CXCR4/HSPA8/HLA-C/CAV1	1.27467065822275
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/81	253/9376	1.83008832284195	BCL2/MYL12B/ACTG1/UBC	1.24945085411506
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/81	88/9376	2.6307519640853	CLU/TFPI	1.43473467167362
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/81	89/9376	2.60119295325288	GNG11/GLUL	1.4167864715793
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/81	23/9376	5.03274288781535	GLUL	1.80755880641798
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/81	170/9376	2.04270152505447	MYL12B/ACTG1/MYL6	1.28071481903743
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/81	91/9376	2.54402387735721	GNG11/GNAS	1.38161552552025
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/81	93/9376	2.4893136864463	MYL12B/ACTG1	1.34737017661367
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/81	93/9376	2.4893136864463	FOS/IL12RB2	1.34737017661367
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/81	95/9376	2.43690708252112	FOS/CCL2	1.31400359167586
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/81	26/9376	4.45204178537512	FADS2	1.64535783326255
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/81	100/9376	2.31506172839506	CD9/CD7	1.2341536145169
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/81	28/9376	4.13403880070547	ELOVL6	1.5503418955209
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/81	103/9376	2.24763274601462	COL1A2/DPP4	1.18849866434988
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/81	103/9376	2.24763274601462	COL1A2/GNAS	1.18849866434988
Human Diseases	Substance dependence	hsa05034	Alcoholism	3/81	191/9376	1.8181113050223	FOSB/GNG11/GNAS	1.06633324125605
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/81	105/9376	2.20482069370958	ACTG1/GNAS	1.15893006059234
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/81	31/9376	3.73397052966945	GLUL	1.42327386122954
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/81	31/9376	3.73397052966945	HSPA5	1.42327386122954
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/81	109/9376	2.12390984256428	FOS/CCL4	1.10173866885884
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/81	32/9376	3.61728395061728	BCL2	1.38440406843104
Human Diseases	Immune disease	hsa05310	Asthma	1/81	32/9376	3.61728395061728	CD40LG	1.38440406843104
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/81	110/9376	2.10460157126824	ID2/DCN	1.08782566753124
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/81	110/9376	2.10460157126824	HSP90AA1/HSP90AB1	1.08782566753124
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/81	200/9376	1.7362962962963	FOS/MYO1D/ACTG1	0.982526701775148
NA	NA	hsa04517	IgSF CAM signaling	4/81	299/9376	1.54853627317395	NCAM1/MYL12B/ACTG1/MYL6	0.899856438859665
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/81	119/9376	1.9454300238614	FOS/CCL2	0.968882673319375
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/81	37/9376	3.12846179512846	GLUL	1.21093263612269
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/81	38/9376	3.0461338531514	CD40LG	1.17978360024605
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/81	122/9376	1.89759158065169	FOS/CD40LG	0.931531163992898
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/81	323/9376	1.43347475442419	DDIT4/BCL2/TIMP3/VIM	0.740069081673394
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/81	44/9376	2.6307519640853	B4GALNT3	1.01211610157939
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/81	44/9376	2.6307519640853	HLA-C	1.01211610157939
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/81	44/9376	2.6307519640853	GNAS	1.01211610157939
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/81	134/9376	1.72765800626497	MYL6/GNAS	0.791954406924993
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/81	45/9376	2.57229080932785	HLA-C	0.986912133870995
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/81	232/9376	1.49680715197957	CXCR4/MYL12B/ACTG1	0.715265328295858
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/81	142/9376	1.63032516084159	FOS/FOSB	0.706508402014658
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/81	52/9376	2.22602089268756	GNAS	0.827564516346464
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/81	53/9376	2.18402049848591	GNAS	0.806905664986797
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/81	55/9376	2.10460157126824	PSAP	0.766936130611192
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/81	56/9376	2.06701940035273	BCL2	0.747587142817973
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/81	56/9376	2.06701940035273	HSPA8	0.747587142817973
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/81	155/9376	1.49358821186778	HLA-C/ACTG1	0.578422352917284
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/81	156/9376	1.48401392845837	EIF2AK2/MX1	0.569060116893241
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/81	59/9376	1.96191671897887	GNAS	0.691876981292552
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/81	60/9376	1.92921810699588	GNAS	0.674034303921989
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/81	61/9376	1.89759158065169	MT2A	0.656531712593874
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/81	163/9376	1.42028326895403	FOS/BCL2	0.505287807287232
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/81	62/9376	1.86698526483473	HSPA8	0.639356220414138
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/81	65/9376	1.78081671415005	GNAS	0.589672761198921
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/81	65/9376	1.78081671415005	KISS1	0.589672761198921
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/81	66/9376	1.75383464272353	IL12RB2	0.573689193987009
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/81	69/9376	1.67758096260512	GNAS	0.527332252743156
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/81	72/9376	1.6076817558299	ISG15	0.483182332349136
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/81	184/9376	1.25818572195384	CXCR4/MYL12B	0.33017149464123
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/81	75/9376	1.54337448559671	GLUL	0.441030375584515
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/81	75/9376	1.54337448559671	BCL2	0.441030375584515
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/81	78/9376	1.48401392845837	FOS	0.40069492370983
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/81	78/9376	1.48401392845837	FOS	0.40069492370983
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/81	80/9376	1.44691358024691	BCL2	0.374734724237528
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/81	195/9376	1.1872111427667	ACTG1/SELPLG	0.246608167960288
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/81	83/9376	1.39461549903317	CCL4	0.337084409892801
NA	NA	hsa04082	Neuroactive ligand signaling	2/81	199/9376	1.16334760220857	GNG11/GNAS	0.217416443241431
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/81	86/9376	1.34596612115992	AREG	0.300869657511819
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/81	86/9376	1.34596612115992	GNAS	0.300869657511819
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/81	86/9376	1.34596612115992	ACTG1	0.300869657511819
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/81	89/9376	1.30059647662644	COL1A2	0.265977326857172
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/81	89/9376	1.30059647662644	GNAS	0.265977326857172
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/81	90/9376	1.28614540466392	GNAS	0.254622713107579
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/81	90/9376	1.28614540466392	FOS	0.254622713107579
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/81	91/9376	1.27201193867861	FOS	0.243400327622186
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/81	212/9376	1.09201024924295	ACTG1/GNAS	0.126492579186021
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/81	93/9376	1.24465684322315	GNAS	0.221339088644174
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/81	93/9376	1.24465684322315	GNAS	0.221339088644174
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/81	93/9376	1.24465684322315	BCL2	0.221339088644174
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/81	98/9376	1.1811539430587	GNAS	0.168281779495523
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/81	99/9376	1.16922309514902	GNAS	0.158007209688912
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/81	99/9376	1.16922309514902	SELPLG	0.158007209688912
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/81	99/9376	1.16922309514902	FOS	0.158007209688912
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/81	99/9376	1.16922309514902	ACTG1	0.158007209688912
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/81	226/9376	1.02436359663498	FOS/GNAS	0.0346089579982029
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/81	101/9376	1.14607016257181	GNAS	0.137774451577414
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/81	102/9376	1.13483418058581	GNAS	0.127811517396579
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/81	105/9376	1.10241034685479	UBC	0.0985096206475975
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/81	107/9376	1.081804545979	GNAS	0.0794431282192301
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/81	110/9376	1.05230078563412	BCL2	0.0515064784667301
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/81	370/9376	0.938538538538539	CSH1/CSH2/KISS1	-0.112600734700194
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/81	117/9376	0.989342618972249	ACTG1	-0.0108284135233012
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/81	250/9376	0.926024691358025	CTSW/PSAP	-0.110667476875952
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/81	254/9376	0.911441625352386	CXCR4/GNAS	-0.133568765508121
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/81	120/9376	0.964609053497942	BCL2	-0.0364229047650202
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/81	122/9376	0.948795790325845	ACTG1	-0.0531403347215791
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/81	125/9376	0.926024691358025	BCL2	-0.0777232410660813
NA	NA	hsa04519	Cadherin signaling	3/81	404/9376	0.85955262192886	MYO1D/ACTG1/VIM	-0.26937862804706
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/81	133/9376	0.870323958043256	HLA-C	-0.140599100039797
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/81	140/9376	0.826807760141093	GNG11	-0.192732047506759
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/81	142/9376	0.815162580420796	UBC	-0.207177498301126
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/81	143/9376	0.809462142795476	CD40LG	-0.21432919280878
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/81	144/9376	0.803840877914952	ID2	-0.221434511211693
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/81	144/9376	0.803840877914952	ERN1	-0.221434511211693
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/81	148/9376	0.782115448782115	FOS	-0.249406032462629
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/81	149/9376	0.776866351810423	GNAS	-0.256289840384023
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/81	150/9376	0.771687242798354	BCL2	-0.263131313580819
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/81	155/9376	0.746794105933891	GNAS	-0.296724973361957
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/81	158/9376	0.732614471011095	CCND3	-0.316410976863355
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/81	158/9376	0.732614471011095	DDIT4	-0.316410976863355
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/81	170/9376	0.680900508351489	ACTG1	-0.391939052434214
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/81	178/9376	0.65029823831322	CCND3	-0.439708204593873
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/81	181/9376	0.639519814473774	BCL2	-0.457138994945303
NA	NA	hsa04382	Cornified envelope formation	1/81	217/9376	0.533424361381351	S100A6	-0.649129501299994
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/81	238/9376	0.486357505965349	GNG11	-0.749250943167509
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/81	243/9376	0.476350149875527	HSPA8	-0.772041848925391