ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/122 68/18639 0.117647058823529 17.9739633558341 1.42268309711204e-08 6.04640316272618e-06 GO:0015078 proton transmembrane transporter activity 10/122 185/18639 0.0540540540540541 8.25830748781569 3.83531988991008e-07 8.15005476605891e-05 GO:0009055 electron transfer activity 8/122 116/18639 0.0689655172413793 10.5364612775579 9.41575634718382e-07 0.000113948385619486 GO:0022853 active monoatomic ion transmembrane transporter activity 8/122 118/18639 0.0677966101694915 10.3578771881078 1.07245539406575e-06 0.000113948385619486 GO:0015399 primary active transmembrane transporter activity 8/122 166/18639 0.0481927710843374 7.36282836263085 1.36083668708878e-05 0.00115671118402546 GO:0031625 ubiquitin protein ligase binding 10/122 302/18639 0.033112582781457 5.05889697101292 2.99162785206481e-05 0.00211906972854591 GO:0044389 ubiquitin-like protein ligase binding 10/122 322/18639 0.031055900621118 4.74467976784441 5.13986546454994e-05 0.00312063260347675 GO:0008191 metalloendopeptidase inhibitor activity 3/122 14/18639 0.214285714285714 32.7382903981265 9.44774747898275e-05 0.00445356958568061 GO:0004129 cytochrome-c oxidase activity 3/122 15/18639 0.2 30.555737704918 0.000117533005702749 0.00445356958568061 GO:0005201 extracellular matrix structural constituent 7/122 168/18639 0.0416666666666667 6.36577868852459 0.000119771813663984 0.00445356958568061 GO:0140662 ATP-dependent protein folding chaperone 4/122 40/18639 0.1 15.277868852459 0.000133062937812607 0.00445356958568061 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/122 16/18639 0.1875 28.6460040983607 0.00014396556168161 0.00445356958568061 GO:0051082 unfolded protein binding 6/122 121/18639 0.0495867768595041 7.57580273675654 0.000144647424369689 0.00445356958568061 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/122 41/18639 0.0975609756097561 14.9052379048381 0.000146705821645949 0.00445356958568061 GO:0048306 calcium-dependent protein binding 5/122 80/18639 0.0625 9.54866803278689 0.000179731713805675 0.00509239855782747 GO:0003954 NADH dehydrogenase activity 4/122 44/18639 0.0909090909090909 13.8889716840537 0.000193702959831687 0.0051452348705292 GO:0031072 heat shock protein binding 6/122 131/18639 0.0458015267175573 6.99749718433237 0.000223062727113707 0.00557656817784268 GO:0002020 protease binding 6/122 136/18639 0.0441176470588235 6.7402362584378 0.000273151469145689 0.00644940968816211 GO:0005544 calcium-dependent phospholipid binding 4/122 53/18639 0.0754716981132075 11.5304670584596 0.0003993031978027 0.00893178205611302 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/122 58/18639 0.0689655172413793 10.5364612775579 0.000564166483131401 0.0119885377665423 GO:0004866 endopeptidase inhibitor activity 6/122 161/18639 0.0372670807453416 5.6936157214133 0.000670318769954311 0.0133572184503499 GO:0023026 MHC class II protein complex binding 3/122 27/18639 0.111111111111111 16.9754098360656 0.000713475778601567 0.0133572184503499 GO:0061134 peptidase regulator activity 7/122 226/18639 0.0309734513274336 4.73208327288554 0.000722861233783643 0.0133572184503499 GO:0022804 active transmembrane transporter activity 10/122 457/18639 0.0218818380743982 3.34307852351401 0.000849607901684109 0.0146787772429344 GO:0030414 peptidase inhibitor activity 6/122 169/18639 0.0355029585798817 5.42409545057717 0.000863457484878494 0.0146787772429344 GO:0061135 endopeptidase regulator activity 6/122 184/18639 0.0326086956521739 4.98191375623664 0.00133856530572454 0.0217474327199034 GO:0051427 hormone receptor binding 3/122 34/18639 0.0882352941176471 13.4804725168756 0.00141176580157994 0.0217474327199034 GO:0003725 double-stranded RNA binding 4/122 75/18639 0.0533333333333333 8.14819672131147 0.00148394246794635 0.0217474327199034 GO:0044183 protein folding chaperone 4/122 75/18639 0.0533333333333333 8.14819672131147 0.00148394246794635 0.0217474327199034 GO:0005154 epidermal growth factor receptor binding 3/122 35/18639 0.0857142857142857 13.0953161592506 0.00153678900245373 0.0217711775347612 GO:0004857 enzyme inhibitor activity 9/122 416/18639 0.0216346153846154 3.30530816519546 0.00166994369513743 0.0228943893688196 GO:0023023 MHC protein complex binding 3/122 37/18639 0.0810810810810811 12.3874612317235 0.00180715113995224 0.0230954333650244 GO:0005131 growth hormone receptor binding 2/122 10/18639 0.2 30.555737704918 0.00184763466920195 0.0230954333650244 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/122 10/18639 0.2 30.555737704918 0.00184763466920195 0.0230954333650244 GO:0001618 virus receptor activity 4/122 81/18639 0.0493827160493827 7.54462659380692 0.00197108353153867 0.0239345857401124 GO:0140272 exogenous protein binding 4/122 82/18639 0.0487804878048781 7.45261895241903 0.00206181173286137 0.0243408329573911 GO:0005126 cytokine receptor binding 7/122 275/18639 0.0254545454545455 3.88891207153502 0.002234364144444 0.025664993551046 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/122 88/18639 0.0454545454545455 6.94448584202683 0.00266753141896649 0.0292786678823468 GO:0004859 phospholipase inhibitor activity 2/122 12/18639 0.166666666666667 25.4631147540984 0.00268674834685065 0.0292786678823468 GO:0048156 tau protein binding 3/122 43/18639 0.0697674418604651 10.6589782691575 0.00278962000160605 0.0296397125170642 GO:0008009 chemokine activity 3/122 45/18639 0.0666666666666667 10.1852459016393 0.00317728185612499 0.0329352387525151 GO:0001664 G protein-coupled receptor binding 7/122 297/18639 0.0235690235690236 3.60084451068058 0.00342492536067265 0.0346569828163303 GO:0044548 S100 protein binding 2/122 14/18639 0.142857142857143 21.8255269320843 0.00367288800189945 0.0363018000187736 GO:0035254 glutamate receptor binding 3/122 49/18639 0.0612244897959184 9.35379725660756 0.00404782728756945 0.0387550154320228 GO:0031386 protein tag activity 2/122 15/18639 0.133333333333333 20.3704918032787 0.00421986569362201 0.0387550154320228 GO:0141047 molecular tag activity 2/122 15/18639 0.133333333333333 20.3704918032787 0.00421986569362201 0.0387550154320228 GO:0048020 CCR chemokine receptor binding 3/122 50/18639 0.06 9.16672131147541 0.0042858487654237 0.0387550154320228 GO:0055102 lipase inhibitor activity 2/122 16/18639 0.125 19.0973360655738 0.00480213714104207 0.0425189226029767 GO:0051787 misfolded protein binding 2/122 17/18639 0.117647058823529 17.9739633558341 0.00541922460445045 0.0470034787120702 GO:0140313 molecular sequestering activity 3/122 55/18639 0.0545454545454545 8.33338301043219 0.00560253747968717 0.047621568577341 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/122 18/18639 0.111111111111111 16.9754098360656 0.00607065499664682 0.0496159302610557 GO:0098641 cadherin binding involved in cell-cell adhesion 2/122 18/18639 0.111111111111111 16.9754098360656 0.00607065499664682 0.0496159302610557 GO:0019887 protein kinase regulator activity 6/122 255/18639 0.0235294117647059 3.59479267116683 0.00668129687420597 0.0535764371988215 GO:0001786 phosphatidylserine binding 3/122 59/18639 0.0508474576271186 7.76840789108086 0.00681234910654242 0.0536157105607505 GO:0015026 coreceptor activity 3/122 61/18639 0.0491803278688525 7.51370599301263 0.00747091316571361 0.0577297835532415 GO:0070182 DNA polymerase binding 2/122 21/18639 0.0952380952380952 14.5503512880562 0.00822634183177453 0.0624320585447174 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/122 22/18639 0.0909090909090909 13.8889716840537 0.00901050473717094 0.0671835879525904 GO:0019957 C-C chemokine binding 2/122 24/18639 0.0833333333333333 12.7315573770492 0.0106745222685864 0.0782184821405035 GO:0097110 scaffold protein binding 3/122 70/18639 0.0428571428571429 6.54765807962529 0.0108910917365425 0.0784527794581452 GO:0019207 kinase regulator activity 6/122 287/18639 0.0209059233449477 3.19397955103673 0.0115640150043942 0.0805775385809745 GO:0051087 protein-folding chaperone binding 4/122 134/18639 0.0298507462686567 4.56055786640568 0.0116818907799206 0.0805775385809745 GO:0042379 chemokine receptor binding 3/122 72/18639 0.0416666666666667 6.36577868852459 0.011754840922401 0.0805775385809745 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/122 26/18639 0.0769230769230769 11.7522068095839 0.0124631773430353 0.0827632870435937 GO:0070412 R-SMAD binding 2/122 26/18639 0.0769230769230769 11.7522068095839 0.0124631773430353 0.0827632870435937 GO:0070851 growth factor receptor binding 4/122 139/18639 0.0287769784172662 4.39650902229037 0.0132162595947474 0.0850200033429961 GO:0015252 proton channel activity 2/122 27/18639 0.0740740740740741 11.3169398907104 0.01340315346819 0.0850200033429961 GO:0035255 ionotropic glutamate receptor binding 2/122 27/18639 0.0740740740740741 11.3169398907104 0.01340315346819 0.0850200033429961 GO:0097718 disordered domain specific binding 2/122 28/18639 0.0714285714285714 10.9127634660422 0.014372988974794 0.0898311810924622 GO:0046332 SMAD binding 3/122 79/18639 0.0379746835443038 5.80172234903507 0.0150818361773884 0.0928953677592764 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/122 30/18639 0.0666666666666667 10.1852459016393 0.016400544502193 0.0989946572214537 GO:0005543 phospholipid binding 8/122 497/18639 0.0160965794768612 2.45921430220668 0.0165379309711134 0.0989946572214537 GO:0005125 cytokine activity 5/122 234/18639 0.0213675213675214 3.26450189155107 0.0189445159384773 0.111825267692401 GO:0019956 chemokine binding 2/122 33/18639 0.0606060606060606 9.25931445603577 0.0196553473879092 0.112885441079208 GO:0071889 14-3-3 protein binding 2/122 33/18639 0.0606060606060606 9.25931445603577 0.0196553473879092 0.112885441079208 GO:0005178 integrin binding 4/122 161/18639 0.0248447204968944 3.79574381427553 0.0214666575686548 0.12089191193166 GO:0008083 growth factor activity 4/122 162/18639 0.0246913580246914 3.77231329690346 0.0219019451559504 0.12089191193166 GO:0072341 modified amino acid binding 3/122 91/18639 0.032967032967033 5.03666006125023 0.0219027699264418 0.12089191193166 GO:0045296 cadherin binding 6/122 334/18639 0.0179640718562874 2.74452733876509 0.0226590286793008 0.123462656265421 GO:0004867 serine-type endopeptidase inhibitor activity 3/122 95/18639 0.0315789473684211 4.82459016393443 0.0244929763423589 0.131766011968386 GO:0000146 microfilament motor activity 2/122 38/18639 0.0526315789473684 8.04098360655738 0.0256222788674179 0.134437882946329 GO:0043531 ADP binding 2/122 38/18639 0.0526315789473684 8.04098360655738 0.0256222788674179 0.134437882946329 GO:0071855 neuropeptide receptor binding 2/122 40/18639 0.05 7.63893442622951 0.0281896746600971 0.146105021104162 GO:1901981 phosphatidylinositol phosphate binding 4/122 185/18639 0.0216216216216216 3.30332299512627 0.0334238202552391 0.170088117924891 GO:0016248 channel inhibitor activity 2/122 44/18639 0.0454545454545455 6.94448584202683 0.0336174162486844 0.170088117924891 GO:0141110 transporter inhibitor activity 2/122 45/18639 0.0444444444444444 6.79016393442623 0.0350332364529895 0.173674358457328 GO:0140597 protein carrier chaperone 4/122 188/18639 0.0212765957446809 3.25061039414022 0.0351435172407769 0.173674358457328 GO:1902936 phosphatidylinositol bisphosphate binding 3/122 111/18639 0.027027027027027 4.12915374390784 0.0364320364127121 0.177972591671295 GO:0005200 structural constituent of cytoskeleton 3/122 112/18639 0.0267857142857143 4.09228629976581 0.0372612817482316 0.179955053897709 GO:0140297 DNA-binding transcription factor binding 7/122 488/18639 0.014344262295082 2.19149758129535 0.0414816121825628 0.198086350309991 GO:0051015 actin filament binding 4/122 209/18639 0.0191387559808612 2.92399403874814 0.0486017768336281 0.227731520738619 GO:0015485 cholesterol binding 2/122 54/18639 0.037037037037037 5.65846994535519 0.0487613373816807 0.227731520738619 GO:0098632 cell-cell adhesion mediator activity 2/122 55/18639 0.0363636363636364 5.55558867362146 0.0503899713402464 0.232779758908747 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/122 128/18639 0.0234375 3.58075051229508 0.0518233736955143 0.235278435987752 GO:0170055 lipid transmembrane transporter activity 2/122 56/18639 0.0357142857142857 5.45638173302108 0.052038054077291 0.235278435987752 GO:0005179 hormone activity 3/122 132/18639 0.0227272727272727 3.47224292101341 0.0558356707071588 0.249707127397345 GO:0016887 ATP hydrolysis activity 6/122 417/18639 0.0143884892086331 2.19825451114518 0.0564044334826944 0.249707127397345 GO:0044325 transmembrane transporter binding 3/122 136/18639 0.0220588235294118 3.3701181292189 0.0599920090723057 0.259799284472905 GO:0030295 protein kinase activator activity 3/122 139/18639 0.0215827338129496 3.29738176671777 0.0632022088397246 0.259799284472905 GO:0005522 profilin binding 1/122 10/18639 0.1 15.277868852459 0.0635744131416049 0.259799284472905 GO:0005528 FK506 binding 1/122 10/18639 0.1 15.277868852459 0.0635744131416049 0.259799284472905 GO:0008140 cAMP response element binding protein binding 1/122 10/18639 0.1 15.277868852459 0.0635744131416049 0.259799284472905 GO:0008239 dipeptidyl-peptidase activity 1/122 10/18639 0.1 15.277868852459 0.0635744131416049 0.259799284472905 GO:0043208 glycosphingolipid binding 1/122 10/18639 0.1 15.277868852459 0.0635744131416049 0.259799284472905 GO:0070513 death domain binding 1/122 10/18639 0.1 15.277868852459 0.0635744131416049 0.259799284472905 GO:0019955 cytokine binding 3/122 144/18639 0.0208333333333333 3.18288934426229 0.0687261087600215 0.264513161701115 GO:0005536 D-glucose binding 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0010854 adenylate cyclase regulator activity 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0019215 intermediate filament binding 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0048407 platelet-derived growth factor binding 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0050998 nitric-oxide synthase binding 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/122 11/18639 0.0909090909090909 13.8889716840537 0.0697069979071174 0.264513161701115 GO:0050840 extracellular matrix binding 2/122 67/18639 0.0298507462686567 4.56055786640568 0.0713614772835461 0.26623878383087 GO:0032934 sterol binding 2/122 68/18639 0.0294117647058824 4.49349083895853 0.0732189327401359 0.26623878383087 GO:0019209 kinase activator activity 3/122 148/18639 0.0202702702702703 3.09686530793088 0.0732981603190957 0.26623878383087 GO:0005527 macrolide binding 1/122 12/18639 0.0833333333333333 12.7315573770492 0.0757997478671417 0.26623878383087 GO:0010853 cyclase activator activity 1/122 12/18639 0.0833333333333333 12.7315573770492 0.0757997478671417 0.26623878383087 GO:0015132 prostaglandin transmembrane transporter activity 1/122 12/18639 0.0833333333333333 12.7315573770492 0.0757997478671417 0.26623878383087 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/122 12/18639 0.0833333333333333 12.7315573770492 0.0757997478671417 0.26623878383087 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/122 12/18639 0.0833333333333333 12.7315573770492 0.0757997478671417 0.26623878383087 GO:0140900 chloride:bicarbonate antiporter activity 1/122 12/18639 0.0833333333333333 12.7315573770492 0.0757997478671417 0.26623878383087 GO:0005518 collagen binding 2/122 72/18639 0.0277777777777778 4.24385245901639 0.0808013963216268 0.275532715599206 GO:0140104 molecular carrier activity 4/122 249/18639 0.0160642570281124 2.45427612087695 0.0810290270248119 0.275532715599206 GO:0071714 icosanoid transmembrane transporter activity 1/122 13/18639 0.0769230769230769 11.7522068095839 0.081852919647901 0.275532715599206 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/122 13/18639 0.0769230769230769 11.7522068095839 0.081852919647901 0.275532715599206 GO:0043539 protein serine/threonine kinase activator activity 2/122 73/18639 0.0273972602739726 4.18571749382439 0.0827337991951932 0.275532715599206 GO:0005161 platelet-derived growth factor receptor binding 1/122 14/18639 0.0714285714285714 10.9127634660422 0.087866768236055 0.275532715599206 GO:0005545 1-phosphatidylinositol binding 1/122 14/18639 0.0714285714285714 10.9127634660422 0.087866768236055 0.275532715599206 GO:0032036 myosin heavy chain binding 1/122 14/18639 0.0714285714285714 10.9127634660422 0.087866768236055 0.275532715599206 GO:0042043 neurexin family protein binding 1/122 14/18639 0.0714285714285714 10.9127634660422 0.087866768236055 0.275532715599206 GO:0017022 myosin binding 2/122 76/18639 0.0263157894736842 4.02049180327869 0.0886150050486092 0.275532715599206 GO:0098631 cell adhesion mediator activity 2/122 76/18639 0.0263157894736842 4.02049180327869 0.0886150050486092 0.275532715599206 GO:0005523 tropomyosin binding 1/122 15/18639 0.0666666666666667 10.1852459016393 0.0938415469890862 0.275532715599206 GO:0033130 acetylcholine receptor binding 1/122 15/18639 0.0666666666666667 10.1852459016393 0.0938415469890862 0.275532715599206 GO:0050780 dopamine receptor binding 1/122 15/18639 0.0666666666666667 10.1852459016393 0.0938415469890862 0.275532715599206 GO:0140776 protein-containing complex destabilizing activity 1/122 15/18639 0.0666666666666667 10.1852459016393 0.0938415469890862 0.275532715599206 GO:0033293 monocarboxylic acid binding 2/122 79/18639 0.0253164556962025 3.86781489935671 0.0946167367576586 0.275532715599206 GO:0016874 ligase activity 3/122 167/18639 0.0179640718562874 2.74452733876509 0.0967719614682626 0.275532715599206 GO:0033192 calmodulin-dependent protein phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0140791 histone H2AXS140 phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/122 81/18639 0.0246913580246914 3.77231329690346 0.0986814595692212 0.275532715599206 GO:0005159 insulin-like growth factor receptor binding 1/122 16/18639 0.0625 9.54866803278689 0.0997775076456224 0.275532715599206 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/122 16/18639 0.0625 9.54866803278689 0.0997775076456224 0.275532715599206 GO:0005521 lamin binding 1/122 16/18639 0.0625 9.54866803278689 0.0997775076456224 0.275532715599206 GO:0008142 oxysterol binding 1/122 16/18639 0.0625 9.54866803278689 0.0997775076456224 0.275532715599206 GO:0008514 organic anion transmembrane transporter activity 4/122 269/18639 0.0148698884758364 2.27180205984521 0.100422449906142 0.275532715599206 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/122 82/18639 0.024390243902439 3.72630947620952 0.1007321468641 0.275532715599206 GO:0033549 MAP kinase phosphatase activity 2/122 82/18639 0.024390243902439 3.72630947620952 0.1007321468641 0.275532715599206 GO:0005525 GTP binding 5/122 378/18639 0.0132275132275132 2.02088212334114 0.102666950782817 0.275532715599206 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/122 83/18639 0.0240963855421687 3.68141418131543 0.102794726673765 0.275532715599206 GO:0004860 protein kinase inhibitor activity 2/122 84/18639 0.0238095238095238 3.63758782201405 0.104868958710864 0.275532715599206 GO:0017018 myosin phosphatase activity 2/122 84/18639 0.0238095238095238 3.63758782201405 0.104868958710864 0.275532715599206 GO:0051117 ATPase binding 2/122 84/18639 0.0238095238095238 3.63758782201405 0.104868958710864 0.275532715599206 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/122 17/18639 0.0588235294117647 8.98698167791707 0.105674900335696 0.275532715599206 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/122 17/18639 0.0588235294117647 8.98698167791707 0.105674900335696 0.275532715599206 GO:0030548 acetylcholine receptor regulator activity 1/122 17/18639 0.0588235294117647 8.98698167791707 0.105674900335696 0.275532715599206 GO:0048038 quinone binding 1/122 17/18639 0.0588235294117647 8.98698167791707 0.105674900335696 0.275532715599206 GO:1990226 histone methyltransferase binding 1/122 17/18639 0.0588235294117647 8.98698167791707 0.105674900335696 0.275532715599206 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/122 86/18639 0.0232558139534884 3.55299275638582 0.109051431239129 0.282602794369694 GO:0031690 adrenergic receptor binding 1/122 18/18639 0.0555555555555556 8.48770491803279 0.111533973590934 0.283843944767346 GO:0035615 clathrin adaptor activity 1/122 18/18639 0.0555555555555556 8.48770491803279 0.111533973590934 0.283843944767346 GO:0099602 neurotransmitter receptor regulator activity 1/122 18/18639 0.0555555555555556 8.48770491803279 0.111533973590934 0.283843944767346 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/122 89/18639 0.0224719101123595 3.43322895560877 0.115406672180919 0.28710927493849 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/122 89/18639 0.0224719101123595 3.43322895560877 0.115406672180919 0.28710927493849 GO:0035091 phosphatidylinositol binding 4/122 284/18639 0.0140845070422535 2.15181251443085 0.116251714723795 0.28710927493849 GO:0015245 fatty acid transmembrane transporter activity 1/122 19/18639 0.0526315789473684 8.04098360655738 0.11735497435469 0.28710927493849 GO:0097001 ceramide binding 1/122 19/18639 0.0526315789473684 8.04098360655738 0.11735497435469 0.28710927493849 GO:0019210 kinase inhibitor activity 2/122 90/18639 0.0222222222222222 3.39508196721311 0.117545914915994 0.28710927493849 GO:0140793 histone H2AXY142 phosphatase activity 2/122 90/18639 0.0222222222222222 3.39508196721311 0.117545914915994 0.28710927493849 GO:0043178 alcohol binding 2/122 92/18639 0.0217391304347826 3.32127583749109 0.121854304438497 0.289136535340586 GO:0019001 guanyl nucleotide binding 5/122 400/18639 0.0125 1.90973360655738 0.122346932543647 0.289136535340586 GO:0032561 guanyl ribonucleotide binding 5/122 400/18639 0.0125 1.90973360655738 0.122346932543647 0.289136535340586 GO:0000339 RNA cap binding 1/122 20/18639 0.05 7.63893442622951 0.123138147992109 0.289136535340586 GO:0001972 retinoic acid binding 1/122 20/18639 0.05 7.63893442622951 0.123138147992109 0.289136535340586 GO:0010851 cyclase regulator activity 1/122 20/18639 0.05 7.63893442622951 0.123138147992109 0.289136535340586 GO:0042288 MHC class I protein binding 1/122 20/18639 0.05 7.63893442622951 0.123138147992109 0.289136535340586 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/122 21/18639 0.0476190476190476 7.2751756440281 0.128883738300125 0.296084263662449 GO:0051428 peptide hormone receptor binding 1/122 21/18639 0.0476190476190476 7.2751756440281 0.128883738300125 0.296084263662449 GO:0072542 protein phosphatase activator activity 1/122 21/18639 0.0476190476190476 7.2751756440281 0.128883738300125 0.296084263662449 GO:0140312 cargo adaptor activity 1/122 21/18639 0.0476190476190476 7.2751756440281 0.128883738300125 0.296084263662449 GO:0004896 cytokine receptor activity 2/122 96/18639 0.0208333333333333 3.18288934426229 0.130584617573158 0.298378830476302 GO:0031683 G-protein beta/gamma-subunit complex binding 1/122 22/18639 0.0454545454545455 6.94448584202683 0.134591987517409 0.305193293177916 GO:0004725 protein tyrosine phosphatase activity 2/122 98/18639 0.0204081632653061 3.11793241886919 0.135003150864584 0.305193293177916 GO:0005212 structural constituent of eye lens 1/122 23/18639 0.0434782608695652 6.64255167498218 0.140263136334236 0.308869600736012 GO:0016493 C-C chemokine receptor activity 1/122 23/18639 0.0434782608695652 6.64255167498218 0.140263136334236 0.308869600736012 GO:0031681 G-protein beta-subunit binding 1/122 23/18639 0.0434782608695652 6.64255167498218 0.140263136334236 0.308869600736012 GO:0099186 structural constituent of postsynapse 1/122 23/18639 0.0434782608695652 6.64255167498218 0.140263136334236 0.308869600736012 GO:0140103 catalytic activity, acting on a glycoprotein 1/122 23/18639 0.0434782608695652 6.64255167498218 0.140263136334236 0.308869600736012 GO:0015149 hexose transmembrane transporter activity 1/122 24/18639 0.0416666666666667 6.36577868852459 0.145897423902308 0.316998069097408 GO:0055056 D-glucose transmembrane transporter activity 1/122 24/18639 0.0416666666666667 6.36577868852459 0.145897423902308 0.316998069097408 GO:0004722 protein serine/threonine phosphatase activity 2/122 103/18639 0.0194174757281553 2.96657647620563 0.146192050689628 0.316998069097408 GO:0019211 phosphatase activator activity 1/122 25/18639 0.04 6.11114754098361 0.1514950878445 0.323246341406079 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/122 25/18639 0.04 6.11114754098361 0.1514950878445 0.323246341406079 GO:0019707 protein-cysteine S-acyltransferase activity 1/122 25/18639 0.04 6.11114754098361 0.1514950878445 0.323246341406079 GO:0051020 GTPase binding 4/122 315/18639 0.0126984126984127 1.94004683840749 0.152115925367567 0.323246341406079 GO:0019888 protein phosphatase regulator activity 2/122 107/18639 0.0186915887850467 2.85567642102038 0.155276873854011 0.325073567675719 GO:0001637 G protein-coupled chemoattractant receptor activity 1/122 26/18639 0.0384615384615385 5.87610340479193 0.157056364264559 0.325073567675719 GO:0004950 chemokine receptor activity 1/122 26/18639 0.0384615384615385 5.87610340479193 0.157056364264559 0.325073567675719 GO:0015145 monosaccharide transmembrane transporter activity 1/122 26/18639 0.0384615384615385 5.87610340479193 0.157056364264559 0.325073567675719 GO:0050750 low-density lipoprotein particle receptor binding 1/122 26/18639 0.0384615384615385 5.87610340479193 0.157056364264559 0.325073567675719 GO:0005496 steroid binding 2/122 108/18639 0.0185185185185185 2.8292349726776 0.157565070449878 0.325073567675719 GO:0004222 metalloendopeptidase activity 2/122 110/18639 0.0181818181818182 2.77779433681073 0.162160570634862 0.332938369660949 GO:0003779 actin binding 5/122 443/18639 0.0112866817155756 1.72436443030011 0.165394300561057 0.33535231855169 GO:0045499 chemorepellent activity 1/122 28/18639 0.0357142857142857 5.45638173302108 0.168070691415317 0.33535231855169 GO:0046625 sphingolipid binding 1/122 28/18639 0.0357142857142857 5.45638173302108 0.168070691415317 0.33535231855169 GO:0051019 mitogen-activated protein kinase binding 1/122 28/18639 0.0357142857142857 5.45638173302108 0.168070691415317 0.33535231855169 GO:0051119 sugar transmembrane transporter activity 1/122 28/18639 0.0357142857142857 5.45638173302108 0.168070691415317 0.33535231855169 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/122 28/18639 0.0357142857142857 5.45638173302108 0.168070691415317 0.33535231855169 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/122 29/18639 0.0344827586206897 5.26823063877897 0.173524206844221 0.33719096240489 GO:0016417 S-acyltransferase activity 1/122 29/18639 0.0344827586206897 5.26823063877897 0.173524206844221 0.33719096240489 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/122 29/18639 0.0344827586206897 5.26823063877897 0.173524206844221 0.33719096240489 GO:0051861 glycolipid binding 1/122 29/18639 0.0344827586206897 5.26823063877897 0.173524206844221 0.33719096240489 GO:0097472 cyclin-dependent protein kinase activity 1/122 29/18639 0.0344827586206897 5.26823063877897 0.173524206844221 0.33719096240489 GO:0001221 transcription coregulator binding 2/122 115/18639 0.0173913043478261 2.65702066999287 0.173752519450991 0.33719096240489 GO:0019208 phosphatase regulator activity 2/122 117/18639 0.0170940170940171 2.61160151324086 0.178426966751284 0.342569649868032 GO:0051721 protein phosphatase 2A binding 1/122 30/18639 0.0333333333333333 5.09262295081967 0.17894226416636 0.342569649868032 GO:0098918 structural constituent of synapse 1/122 30/18639 0.0333333333333333 5.09262295081967 0.17894226416636 0.342569649868032 GO:0005164 tumor necrosis factor receptor binding 1/122 31/18639 0.032258064516129 4.92834479111581 0.184325092033075 0.348169618284698 GO:0005452 solute:inorganic anion antiporter activity 1/122 31/18639 0.032258064516129 4.92834479111581 0.184325092033075 0.348169618284698 GO:0070325 lipoprotein particle receptor binding 1/122 31/18639 0.032258064516129 4.92834479111581 0.184325092033075 0.348169618284698 GO:0015106 bicarbonate transmembrane transporter activity 1/122 32/18639 0.03125 4.77433401639344 0.189672917633461 0.353324081251487 GO:0043425 bHLH transcription factor binding 1/122 32/18639 0.03125 4.77433401639344 0.189672917633461 0.353324081251487 GO:0030296 protein tyrosine kinase activator activity 1/122 33/18639 0.0303030303030303 4.62965722801788 0.194985966703634 0.353324081251487 GO:0140311 protein sequestering activity 1/122 33/18639 0.0303030303030303 4.62965722801788 0.194985966703634 0.353324081251487 GO:0140416 transcription regulator inhibitor activity 1/122 33/18639 0.0303030303030303 4.62965722801788 0.194985966703634 0.353324081251487 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/122 349/18639 0.0114613180515759 1.75104514068298 0.195605168403267 0.353324081251487 GO:0008376 acetylgalactosaminyltransferase activity 1/122 34/18639 0.0294117647058824 4.49349083895853 0.200264463535955 0.353324081251487 GO:0090482 vitamin transmembrane transporter activity 1/122 34/18639 0.0294117647058824 4.49349083895853 0.200264463535955 0.353324081251487 GO:0042826 histone deacetylase binding 2/122 127/18639 0.015748031496063 2.40596359881244 0.202066711508104 0.353324081251487 GO:0016409 palmitoyltransferase activity 1/122 36/18639 0.0277777777777778 4.24385245901639 0.210718690492555 0.353324081251487 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/122 36/18639 0.0277777777777778 4.24385245901639 0.210718690492555 0.353324081251487 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/122 36/18639 0.0277777777777778 4.24385245901639 0.210718690492555 0.353324081251487 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/122 36/18639 0.0277777777777778 4.24385245901639 0.210718690492555 0.353324081251487 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/122 484/18639 0.0103305785123967 1.57829223682428 0.211248580208955 0.353324081251487 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/122 243/18639 0.0123456790123457 1.88615664845173 0.213138284943466 0.353324081251487 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0004711 ribosomal protein S6 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0035175 histone H3S10 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0035979 histone H2AXS139 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0044022 histone H3S28 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0044023 histone H4S1 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0044024 histone H2AS1 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0044025 histone H2BS14 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0072354 histone H3T3 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0072371 histone H2AS121 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0140823 histone H2BS36 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0140855 histone H3S57 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0140995 histone H2A kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0140997 histone H4 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0140998 histone H2B kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:1990244 histone H2AT120 kinase activity 3/122 245/18639 0.0122448979591837 1.87075945132151 0.216542987560508 0.353324081251487 GO:0004677 DNA-dependent protein kinase activity 3/122 246/18639 0.0121951219512195 1.86315473810476 0.21824972984205 0.353324081251487 GO:0140857 histone H3T45 kinase activity 3/122 246/18639 0.0121951219512195 1.86315473810476 0.21824972984205 0.353324081251487 GO:0001216 DNA-binding transcription activator activity 5/122 491/18639 0.010183299389002 1.55579112550499 0.219467754922497 0.353324081251487 GO:0033218 amide binding 3/122 247/18639 0.0121457489878543 1.85561160151324 0.219959328932094 0.353324081251487 GO:0035402 histone H3T11 kinase activity 3/122 247/18639 0.0121457489878543 1.85561160151324 0.219959328932094 0.353324081251487 GO:0035403 histone H3T6 kinase activity 3/122 247/18639 0.0121457489878543 1.85561160151324 0.219959328932094 0.353324081251487 GO:0005501 retinoid binding 1/122 38/18639 0.0263157894736842 4.02049180327869 0.221037364313457 0.353324081251487 GO:0019840 isoprenoid binding 1/122 38/18639 0.0263157894736842 4.02049180327869 0.221037364313457 0.353324081251487 GO:0004679 AMP-activated protein kinase activity 3/122 248/18639 0.0120967741935484 1.84812929666843 0.221671732179862 0.353324081251487 GO:0046982 protein heterodimerization activity 4/122 369/18639 0.010840108401084 1.65613754498201 0.222810789945704 0.353324081251487 GO:0042277 peptide binding 3/122 249/18639 0.0120481927710843 1.84070709065771 0.223386887120777 0.353324081251487 GO:0140789 histone phosphatase activity 2/122 136/18639 0.0147058823529412 2.24674541947927 0.223633359662706 0.353324081251487 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/122 39/18639 0.0256410256410256 3.91740226986129 0.226146414448061 0.355971207927503 GO:0004177 aminopeptidase activity 1/122 40/18639 0.025 3.81946721311475 0.231222228288778 0.361284731701216 GO:0015144 carbohydrate transmembrane transporter activity 1/122 40/18639 0.025 3.81946721311475 0.231222228288778 0.361284731701216 GO:0004713 protein tyrosine kinase activity 2/122 140/18639 0.0142857142857143 2.18255269320843 0.233279066939996 0.363163382598894 GO:0042287 MHC protein binding 1/122 41/18639 0.024390243902439 3.72630947620952 0.23626502027484 0.365136849515662 GO:0140828 metal cation:monoatomic cation antiporter activity 1/122 41/18639 0.024390243902439 3.72630947620952 0.23626502027484 0.365136849515662 GO:0008307 structural constituent of muscle 1/122 42/18639 0.0238095238095238 3.63758782201405 0.241275003473381 0.368855670777651 GO:0016859 cis-trans isomerase activity 1/122 42/18639 0.0238095238095238 3.63758782201405 0.241275003473381 0.368855670777651 GO:0051879 Hsp90 protein binding 1/122 42/18639 0.0238095238095238 3.63758782201405 0.241275003473381 0.368855670777651 GO:0019903 protein phosphatase binding 2/122 144/18639 0.0138888888888889 2.1219262295082 0.242950326674874 0.370085623071045 GO:0008200 ion channel inhibitor activity 1/122 43/18639 0.0232558139534884 3.55299275638582 0.246252389588144 0.373775948482005 GO:0001046 core promoter sequence-specific DNA binding 1/122 44/18639 0.0227272727272727 3.47224292101341 0.251197388968131 0.377239895093483 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/122 44/18639 0.0227272727272727 3.47224292101341 0.251197388968131 0.377239895093483 GO:0030547 signaling receptor inhibitor activity 1/122 44/18639 0.0227272727272727 3.47224292101341 0.251197388968131 0.377239895093483 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/122 45/18639 0.0222222222222222 3.39508196721311 0.256110210616203 0.380410989126675 GO:0042605 peptide antigen binding 1/122 45/18639 0.0222222222222222 3.39508196721311 0.256110210616203 0.380410989126675 GO:0000510 H3-H4 histone complex chaperone activity 2/122 151/18639 0.0132450331125828 2.02355878840517 0.259913459378111 0.380410989126675 GO:0140584 chromatin extrusion motor activity 2/122 151/18639 0.0132450331125828 2.02355878840517 0.259913459378111 0.380410989126675 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/122 151/18639 0.0132450331125828 2.02355878840517 0.259913459378111 0.380410989126675 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/122 151/18639 0.0132450331125828 2.02355878840517 0.259913459378111 0.380410989126675 GO:0030276 clathrin binding 1/122 46/18639 0.0217391304347826 3.32127583749109 0.260991062197618 0.380410989126675 GO:0030291 protein serine/threonine kinase inhibitor activity 1/122 46/18639 0.0217391304347826 3.32127583749109 0.260991062197618 0.380410989126675 GO:0015616 DNA translocase activity 2/122 152/18639 0.0131578947368421 2.01024590163934 0.262338934022562 0.380410989126675 GO:0140674 ATP-dependent histone chaperone activity 2/122 152/18639 0.0131578947368421 2.01024590163934 0.262338934022562 0.380410989126675 GO:0003774 cytoskeletal motor activity 2/122 153/18639 0.0130718954248366 1.99710703953713 0.264764623277185 0.380410989126675 GO:0061775 cohesin loader activity 2/122 153/18639 0.0130718954248366 1.99710703953713 0.264764623277185 0.380410989126675 GO:0001784 phosphotyrosine residue binding 1/122 47/18639 0.0212765957446809 3.25061039414022 0.265840150048524 0.380410989126675 GO:0005504 fatty acid binding 1/122 47/18639 0.0212765957446809 3.25061039414022 0.265840150048524 0.380410989126675 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/122 48/18639 0.0208333333333333 3.18288934426229 0.270657679184393 0.38343171217789 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/122 48/18639 0.0208333333333333 3.18288934426229 0.270657679184393 0.38343171217789 GO:0032266 phosphatidylinositol-3-phosphate binding 1/122 48/18639 0.0208333333333333 3.18288934426229 0.270657679184393 0.38343171217789 GO:0140375 immune receptor activity 2/122 156/18639 0.0128205128205128 1.95870113493064 0.272041927081205 0.38411235551333 GO:0004175 endopeptidase activity 4/122 405/18639 0.00987654320987654 1.50892531876138 0.273987111832702 0.385577889168538 GO:0001222 transcription corepressor binding 1/122 49/18639 0.0204081632653061 3.11793241886919 0.275443853308405 0.38634863912895 GO:0140658 ATP-dependent chromatin remodeler activity 2/122 158/18639 0.0126582278481013 1.93390744967836 0.276892631494366 0.386881755921984 GO:0030246 carbohydrate binding 3/122 280/18639 0.0107142857142857 1.63691451990632 0.277644554249894 0.386881755921984 GO:0005006 epidermal growth factor receptor activity 1/122 50/18639 0.02 3.0555737704918 0.280198874819775 0.387897465141382 GO:0032813 tumor necrosis factor receptor superfamily binding 1/122 50/18639 0.02 3.0555737704918 0.280198874819775 0.387897465141382 GO:0003689 DNA clamp loader activity 2/122 160/18639 0.0125 1.90973360655738 0.281741735729769 0.388767005471272 GO:0003743 translation initiation factor activity 1/122 51/18639 0.0196078431372549 2.99566055930569 0.284922944822034 0.390620166288272 GO:0030544 Hsp70 protein binding 1/122 51/18639 0.0196078431372549 2.99566055930569 0.284922944822034 0.390620166288272 GO:0140713 histone chaperone activity 2/122 164/18639 0.0121951219512195 1.86315473810476 0.291432051231008 0.398259233997359 GO:0003925 G protein activity 1/122 54/18639 0.0185185185185185 2.8292349726776 0.298911437546518 0.407171028709199 GO:0016247 channel regulator activity 2/122 168/18639 0.0119047619047619 1.81879391100703 0.301106888867641 0.408851206928906 GO:0141108 transporter regulator activity 2/122 170/18639 0.0117647058823529 1.79739633558341 0.305936718819978 0.4140863232436 GO:0016504 peptidase activator activity 1/122 57/18639 0.0175438596491228 2.68032786885246 0.31262848374741 0.42180033521476 GO:0004674 protein serine/threonine kinase activity 4/122 433/18639 0.0092378752886836 1.4113504713588 0.315083396094228 0.423767225759641 GO:0004721 phosphoprotein phosphatase activity 2/122 175/18639 0.0114285714285714 1.74604215456674 0.317983717123468 0.426318863651337 GO:0015459 potassium channel regulator activity 1/122 59/18639 0.0169491525423729 2.58946929702695 0.32162496182611 0.427158152425302 GO:0045309 protein phosphorylated amino acid binding 1/122 59/18639 0.0169491525423729 2.58946929702695 0.32162496182611 0.427158152425302 GO:0070063 RNA polymerase binding 1/122 59/18639 0.0169491525423729 2.58946929702695 0.32162496182611 0.427158152425302 GO:0005319 lipid transporter activity 2/122 178/18639 0.0112359550561798 1.71661447780438 0.325189772989727 0.430384180008757 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/122 60/18639 0.0166666666666667 2.54631147540984 0.326079308147811 0.430384180008757 GO:0019905 syntaxin binding 1/122 61/18639 0.0163934426229508 2.50456866433754 0.330504644517151 0.43487453225941 GO:0005216 monoatomic ion channel activity 4/122 448/18639 0.00892857142857143 1.36409543325527 0.337348942048491 0.44251018632904 GO:0005507 copper ion binding 1/122 63/18639 0.0158730158730159 2.42505854800937 0.33926903572889 0.442655006268976 GO:0008237 metallopeptidase activity 2/122 184/18639 0.0108695652173913 1.66063791874555 0.339542428338085 0.442655006268976 GO:0031406 carboxylic acid binding 2/122 187/18639 0.0106951871657754 1.63399666871219 0.34668514048616 0.450584662711369 GO:0043177 organic acid binding 2/122 189/18639 0.0105820105820106 1.61670569867291 0.351433243683872 0.45536319684648 GO:0019902 phosphatase binding 2/122 190/18639 0.0105263157894737 1.60819672131148 0.353802987353723 0.457040333207697 GO:1990841 promoter-specific chromatin binding 1/122 68/18639 0.0147058823529412 2.24674541947927 0.360685310291464 0.464518960223856 GO:0003924 GTPase activity 3/122 331/18639 0.00906344410876133 1.38470110445248 0.368827431962308 0.472438384160141 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/122 70/18639 0.0142857142857143 2.18255269320843 0.369057749508628 0.472438384160141 GO:0004521 RNA endonuclease activity 1/122 73/18639 0.0136986301369863 2.09285874691219 0.381412925529427 0.486788268318337 GO:0048029 monosaccharide binding 1/122 74/18639 0.0135135135135135 2.06457687195392 0.385477754953396 0.490471967103391 GO:0005261 monoatomic cation channel activity 3/122 341/18639 0.00879765395894428 1.34409403394068 0.386607315246202 0.490471967103391 GO:0003724 RNA helicase activity 1/122 77/18639 0.012987012987013 1.98413881200766 0.397513968559461 0.502807847136223 GO:0008094 ATP-dependent activity, acting on DNA 2/122 210/18639 0.00952380952380952 1.45503512880562 0.400498980457732 0.504811792049625 GO:0019199 transmembrane receptor protein kinase activity 1/122 78/18639 0.0128205128205128 1.95870113493064 0.401473848735937 0.504811792049625 GO:0008186 ATP-dependent activity, acting on RNA 1/122 79/18639 0.0126582278481013 1.93390744967836 0.40540791427412 0.50675989284265 GO:0015370 solute:sodium symporter activity 1/122 79/18639 0.0126582278481013 1.93390744967836 0.40540791427412 0.50675989284265 GO:0141003 histone H2AX kinase activity 3/122 354/18639 0.00847457627118644 1.29473464851348 0.409546769241725 0.51043219040391 GO:0140996 histone H3 kinase activity 3/122 357/18639 0.00840336134453781 1.28385452541672 0.414806368475123 0.515475750298033 GO:0035173 histone kinase activity 3/122 360/18639 0.00833333333333333 1.27315573770492 0.420051591601322 0.518102859154209 GO:0001540 amyloid-beta binding 1/122 83/18639 0.0120481927710843 1.84070709065771 0.420889352131608 0.518102859154209 GO:0008135 translation factor activity, RNA binding 1/122 83/18639 0.0120481927710843 1.84070709065771 0.420889352131608 0.518102859154209 GO:0106310 protein serine kinase activity 3/122 361/18639 0.00831024930747922 1.26962899050906 0.421796680629074 0.518102859154209 GO:0180051 translation factor activity 1/122 84/18639 0.0119047619047619 1.81879391100703 0.424696826751135 0.520161819507874 GO:0004197 cysteine-type endopeptidase activity 1/122 88/18639 0.0113636363636364 1.73612146050671 0.439680034678466 0.536965559592954 GO:0003727 single-stranded RNA binding 1/122 89/18639 0.0112359550561798 1.71661447780438 0.443364959252301 0.538386439559437 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/122 229/18639 0.00873362445414847 1.33431169017109 0.443377067872478 0.538386439559437 GO:0000287 magnesium ion binding 2/122 230/18639 0.00869565217391304 1.32851033499644 0.445588085879925 0.539529733615293 GO:0052689 carboxylic ester hydrolase activity 1/122 92/18639 0.0108695652173913 1.66063791874555 0.454276135365388 0.548486811165596 GO:0051219 phosphoprotein binding 1/122 93/18639 0.010752688172043 1.6427815970386 0.457865843214928 0.551254910386245 GO:0005539 glycosaminoglycan binding 2/122 242/18639 0.00826446280991736 1.26263378945942 0.471735616733486 0.566349257377772 GO:0005249 voltage-gated potassium channel activity 1/122 98/18639 0.0102040816326531 1.55896620943459 0.475466092932764 0.569219970412464 GO:0043130 ubiquitin binding 1/122 100/18639 0.01 1.5277868852459 0.482346446022652 0.575834942583222 GO:0008238 exopeptidase activity 1/122 102/18639 0.00980392156862745 1.49783027965284 0.489137279094723 0.582306284636576 GO:0000149 SNARE binding 1/122 106/18639 0.00943396226415094 1.44130838230745 0.502454991359809 0.596489864044466 GO:0003730 mRNA 3'-UTR binding 2/122 262/18639 0.00763358778625954 1.16624953072206 0.513645155591971 0.608075741299687 GO:0043022 ribosome binding 1/122 112/18639 0.00892857142857143 1.36409543325527 0.521788564018202 0.616000388077044 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/122 268/18639 0.00746268656716418 1.14013946660142 0.525790391538467 0.619005308597918 GO:0035401 histone H3Y41 kinase activity 1/122 115/18639 0.00869565217391304 1.32851033499644 0.531174039264224 0.621897979854808 GO:0140801 histone H2AXY142 kinase activity 1/122 115/18639 0.00869565217391304 1.32851033499644 0.531174039264224 0.621897979854808 GO:0015294 solute:monoatomic cation symporter activity 1/122 116/18639 0.00862068965517241 1.31705765969474 0.534261750730957 0.623794626540266 GO:0016791 phosphatase activity 2/122 273/18639 0.00732600732600733 1.11925779138894 0.535756167415921 0.623825674388401 GO:1990782 protein tyrosine kinase binding 1/122 117/18639 0.00854700854700855 1.30580075662043 0.537329291972161 0.623947948328329 GO:0008017 microtubule binding 2/122 276/18639 0.0072463768115942 1.10709194583036 0.541667204237984 0.627271285561698 GO:0001217 DNA-binding transcription repressor activity 2/122 278/18639 0.00719424460431655 1.09912725557259 0.545579206819525 0.62933654118501 GO:0032182 ubiquitin-like protein binding 1/122 120/18639 0.00833333333333333 1.27315573770492 0.54641219693475 0.62933654118501 GO:0004540 RNA nuclease activity 1/122 121/18639 0.00826446280991736 1.26263378945942 0.549400355689217 0.6293669842801 GO:0015108 chloride transmembrane transporter activity 1/122 121/18639 0.00826446280991736 1.26263378945942 0.549400355689217 0.6293669842801 GO:0031267 small GTPase binding 2/122 283/18639 0.00706713780918728 1.07970804611018 0.555258266364748 0.634367643024242 GO:0005267 potassium channel activity 1/122 124/18639 0.00806451612903226 1.23208619777895 0.558248186217426 0.636073670623072 GO:0015291 secondary active transmembrane transporter activity 2/122 287/18639 0.00696864111498258 1.06465985034558 0.562897158108277 0.639655861486678 GO:0004519 endonuclease activity 1/122 127/18639 0.0078740157480315 1.20298179940622 0.56692367983903 0.642513503817567 GO:0031490 chromatin DNA binding 1/122 128/18639 0.0078125 1.19358350409836 0.569777791283479 0.644030748126273 GO:0015297 antiporter activity 1/122 135/18639 0.00740740740740741 1.13169398907104 0.589240912883819 0.664263628582555 GO:0019838 growth factor binding 1/122 136/18639 0.00735294117647059 1.12337270973963 0.591949116981754 0.665551255865729 GO:0020037 heme binding 1/122 142/18639 0.00704225352112676 1.07590625721542 0.607830420897425 0.681604033987878 GO:0022843 voltage-gated monoatomic cation channel activity 1/122 143/18639 0.00699300699300699 1.0683824372349 0.610417039735643 0.68270326812539 GO:0008194 UDP-glycosyltransferase activity 1/122 145/18639 0.00689655172413793 1.05364612775579 0.615539622570859 0.68662556323521 GO:0015293 symporter activity 1/122 146/18639 0.00684931506849315 1.0464293734561 0.618075805443486 0.686791405173323 GO:0022836 gated channel activity 2/122 318/18639 0.00628930817610063 0.960872254871636 0.61892025454443 0.686791405173323 GO:0008509 monoatomic anion transmembrane transporter activity 1/122 149/18639 0.00671140939597315 1.02536032566839 0.625585218394166 0.692379473483126 GO:0046906 tetrapyrrole binding 1/122 152/18639 0.00657894736842105 1.00512295081967 0.632948167495485 0.698709016066445 GO:0004386 helicase activity 1/122 155/18639 0.00645161290322581 0.985668958223162 0.640167486232257 0.704847620851578 GO:0140097 catalytic activity, acting on DNA 2/122 336/18639 0.00595238095238095 0.909396955503513 0.648861760752793 0.712216998901223 GO:0015079 potassium ion transmembrane transporter activity 1/122 160/18639 0.00625 0.954866803278689 0.651888029582531 0.712216998901223 GO:0099106 ion channel regulator activity 1/122 160/18639 0.00625 0.954866803278689 0.651888029582531 0.712216998901223 GO:0015081 sodium ion transmembrane transporter activity 1/122 164/18639 0.00609756097560976 0.931577369052379 0.6609911857644 0.720310907563769 GO:0015103 inorganic anion transmembrane transporter activity 1/122 165/18639 0.00606060606060606 0.925931445603577 0.663229836662194 0.72090199637195 GO:0005244 voltage-gated monoatomic ion channel activity 1/122 173/18639 0.00578034682080925 0.883113806500521 0.680619114453131 0.737916131741277 GO:0003823 antigen binding 1/122 174/18639 0.00574712643678161 0.878038439796495 0.682729179872643 0.738320359913164 GO:0022832 voltage-gated channel activity 1/122 175/18639 0.00571428571428571 0.873021077283372 0.684825418164305 0.738707621116319 GO:0004252 serine-type endopeptidase activity 1/122 176/18639 0.00568181818181818 0.868060730253353 0.686907919192466 0.738952970831621 GO:0043021 ribonucleoprotein complex binding 1/122 177/18639 0.00564971751412429 0.863156432342317 0.688976772242269 0.738952970831621 GO:0042578 phosphoric ester hydrolase activity 2/122 363/18639 0.00550964187327824 0.841755859639615 0.690269010400362 0.738952970831621 GO:0016853 isomerase activity 1/122 180/18639 0.00555555555555556 0.848770491803279 0.695102327762486 0.74225751080165 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/122 181/18639 0.00552486187845304 0.844081152069559 0.697117470295287 0.742543671367161 GO:0015276 ligand-gated monoatomic ion channel activity 1/122 186/18639 0.00537634408602151 0.821390798519302 0.706996740731343 0.749664519340547 GO:0008234 cysteine-type peptidase activity 1/122 187/18639 0.0053475935828877 0.816998334356097 0.708933899872446 0.749664519340547 GO:0022834 ligand-gated channel activity 1/122 188/18639 0.00531914893617021 0.812652598535054 0.710858355986448 0.749664519340547 GO:0046943 carboxylic acid transmembrane transporter activity 1/122 188/18639 0.00531914893617021 0.812652598535054 0.710858355986448 0.749664519340547 GO:0005342 organic acid transmembrane transporter activity 1/122 189/18639 0.00529100529100529 0.808352849336456 0.712770191690185 0.749820127396853 GO:0015631 tubulin binding 2/122 385/18639 0.00519480519480519 0.793655524803066 0.720995323187694 0.75566318231485 GO:0008236 serine-type peptidase activity 1/122 194/18639 0.00515463917525773 0.787519013013351 0.722142918533719 0.75566318231485 GO:0140098 catalytic activity, acting on RNA 2/122 387/18639 0.00516795865633075 0.789553945863515 0.723658624005045 0.75566318231485 GO:0016758 hexosyltransferase activity 1/122 197/18639 0.0050761421319797 0.775526337688275 0.727620282289361 0.757937794051417 GO:0017171 serine hydrolase activity 1/122 198/18639 0.00505050505050505 0.771609538002981 0.729422165250032 0.757957017680351 GO:0003714 transcription corepressor activity 1/122 204/18639 0.00490196078431373 0.748915139826422 0.739987855693813 0.767060582121636 GO:0005516 calmodulin binding 1/122 207/18639 0.00483091787439614 0.738061297220242 0.745116206381191 0.770497293703178 GO:0004518 nuclease activity 1/122 209/18639 0.00478468899521531 0.730998509687034 0.748479243531142 0.77209630704062 GO:0005085 guanyl-nucleotide exchange factor activity 1/122 230/18639 0.00434782608695652 0.664255167498218 0.781240073240961 0.803939542681376 GO:0046873 metal ion transmembrane transporter activity 2/122 450/18639 0.00444444444444444 0.679016393442623 0.79720048204046 0.818382137360376 GO:0003713 transcription coactivator activity 1/122 256/18639 0.00390625 0.59679175204918 0.815992503276216 0.835654973234679 GO:0016757 glycosyltransferase activity 1/122 267/18639 0.00374531835205993 0.572204825934795 0.828991894816958 0.846926815618286 GO:0005096 GTPase activator activity 1/122 271/18639 0.003690036900369 0.56375899824572 0.833489557545053 0.849479764884047 GO:0003712 transcription coregulator activity 2/122 495/18639 0.00404040404040404 0.617287630402385 0.838667955990656 0.852712634679495 GO:0061630 ubiquitin protein ligase activity 1/122 353/18639 0.0028328611898017 0.432800817350114 0.903707942489717 0.9166488676805 GO:0061659 ubiquitin-like protein ligase activity 1/122 372/18639 0.00268817204301075 0.410695399259651 0.915213648279283 0.926109048854036 GO:0004842 ubiquitin-protein transferase activity 1/122 449/18639 0.0022271714922049 0.340264339698419 0.949444643793389 0.958465495515891 GO:0019787 ubiquitin-like protein transferase activity 1/122 479/18639 0.00208768267223382 0.318953420719395 0.958693494507249 0.963167635724533 GO:0030695 GTPase regulator activity 1/122 489/18639 0.00204498977505112 0.312430855878508 0.961386732091441 0.963167635724533 GO:0060589 nucleoside-triphosphatase regulator activity 1/122 490/18639 0.00204081632653061 0.311793241886919 0.961646281330275 0.963167635724533 GO:0016755 aminoacyltransferase activity 1/122 496/18639 0.00201612903225806 0.308021549444738 0.963167635724533 0.963167635724533