category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/1 69/9376 135.884057971014 FOS 11.6139596163847 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/1 71/9376 132.056338028169 FOS 11.4479840158942 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/1 78/9376 120.205128205128 FOS 10.9181101022626 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/1 78/9376 120.205128205128 FOS 10.9181101022626 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/1 87/9376 107.770114942529 FOS 10.3329625443301 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/1 90/9376 104.177777777778 FOS 10.1576462715423 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/1 91/9376 103.032967032967 FOS 10.1011369178408 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/1 93/9376 100.817204301075 FOS 9.99085603444846 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/1 94/9376 99.7446808510638 FOS 9.93703581814335 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/1 95/9376 98.6947368421053 FOS 9.88406479349995 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/1 97/9376 96.659793814433 FOS 9.7805824885041 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/1 99/9376 94.7070707070707 FOS 9.68024125252417 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/1 99/9376 94.7070707070707 FOS 9.68024125252417 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/1 103/9376 91.0291262135922 FOS 9.48836794257011 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/1 109/9376 86.0183486238532 FOS 9.22053949744012 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/1 109/9376 86.0183486238532 FOS 9.22053949744012 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/1 115/9376 81.5304347826087 FOS 8.97387512631019 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 1/1 115/9376 81.5304347826087 FOS 8.97387512631019 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/1 119/9376 78.7899159663865 FOS 8.81985918064379 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/1 122/9376 76.8524590163935 FOS 8.70933172042456 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/1 122/9376 76.8524590163935 FOS 8.70933172042456 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/1 130/9376 72.1230769230769 FOS 8.43344988264452 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/1 133/9376 70.4962406015038 FOS 8.33644052347906 Human Diseases Infectious disease: viral hsa05162 Measles 1/1 136/9376 68.9411764705882 FOS 8.2426437791881 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/1 137/9376 68.4379562043796 FOS 8.21206162935834 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/1 138/9376 67.9420289855072 FOS 8.18181086224237 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/1 139/9376 67.4532374100719 FOS 8.15188551257143 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/1 142/9376 66.0281690140845 FOS 8.06400452716171 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/1 142/9376 66.0281690140845 FOS 8.06400452716171 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/1 148/9376 63.3513513513514 FOS 7.89628718774535 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/1 154/9376 60.8831168831169 FOS 7.73841824167684 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/1 157/9376 59.7197452229299 FOS 7.66288100018067 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/1 163/9376 57.521472392638 FOS 7.51807637581835 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/1 196/9376 47.8367346938775 FOS 6.84373689543056 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/1 200/9376 46.88 FOS 6.77347768875044 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/1 214/9376 43.8130841121495 FOS 6.54317079955502 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/1 216/9376 43.4074074074074 FOS 6.51209700537449 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/1 217/9376 43.2073732718894 FOS 6.49672019344295 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/1 224/9376 41.8571428571429 FOS 6.39195923462774 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/1 226/9376 41.4867256637168 FOS 6.36291801485111 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/1 227/9376 41.3039647577093 FOS 6.34854036434433 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/1 238/9376 39.3949579831933 FOS 6.19636651459493 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/1 248/9376 37.8064516129032 FOS 6.06683209038319 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/1 300/9376 31.2533333333333 FOS 5.50030302195555