category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	15/105	227/9376	5.90056639395846	MT-ND2/MT-ND3/MT-CYB/FOS/MT-CO2/MT-ND1/AKT3/MT-CO3/MT-CO1/MT-ND4/PRKD3/MAPK1/MT-ATP6/MT-ND5/HMOX1	7.95406964831507
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	14/105	268/9376	4.66467661691542	MT-ND2/MT-ND3/MT-CYB/MT-CO2/MT-ND1/MT-CO3/MT-CO1/MT-ND4/MT-ATP6/HSPA5/MT-ND5/SLC39A10/SNCA/PRKN	6.47751668512841
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	13/105	235/9376	4.93973657548126	MT-ND2/RPS6KA2/MT-ND3/MT-CYB/MT-CO2/MT-ND1/ADCY3/MT-CO3/MT-CO1/MT-ND4/MT-ATP6/MT-ND5/ADCY9	6.50910471378919
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	12/105	205/9376	5.22703832752613	MT-ND2/MT-ND3/MT-CYB/PLCB1/MT-CO2/MT-ND1/AKT3/MT-CO3/MT-CO1/MT-ND4/MT-ATP6/MT-ND5	6.51211058211746
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	10/105	138/9376	6.47066942719117	MT-ND2/MT-ND3/MT-CYB/MT-CO2/MT-ND1/MT-CO3/MT-CO1/MT-ND4/MT-ATP6/MT-ND5	6.88982251084823
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	16/105	388/9376	3.68227785959745	MT-ND2/MT-ND3/MT-CYB/PLCB1/MT-CO2/MT-ND1/AKT3/MT-CO3/MT-CO1/MT-ND4/EIF2AK2/MAPK1/MT-ATP6/MT-ND5/SLC39A10/SNCA	5.74255406821953
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	15/105	362/9376	3.70007892659826	CCND3/CSH1/DDIT4/AREG/ITGA1/AKT3/PDGFD/LPAR3/CSH2/MAPK1/ITGB1/IL2RA/HSP90AB1/COL9A2/COL4A4	5.5755660489649
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	9/105	149/9376	5.39367209971237	MT-ND2/MT-ND3/PLCB1/MT-ND1/ADCY3/MT-ND4/MAPK1/MT-ND5/ADCY9	5.75317405746958
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	12/105	275/9376	3.89651948051948	MT-ND2/MT-ND3/MT-CYB/MT-CO2/MT-ND1/MT-CO3/MT-CO1/MT-ND4/MAPK1/MT-ATP6/HSPA5/MT-ND5	5.18818245403713
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	8/105	122/9376	5.85542544886807	CSH1/FOS/PLCB1/AKT3/ADCY3/CSH2/MAPK1/ADCY9	5.74459552031225
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	16/105	480/9376	2.97650793650794	MT-ND2/MT-ND3/MT-CYB/PLCB1/MT-CO2/MT-ND1/MT-CO3/MT-CO1/MT-ND4/HIP1/MAPK1/MT-ATP6/HSPA5/MT-ND5/SNCA/PRKN	4.73084578579057
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	10/105	212/9376	4.21203953279425	PLCB1/AKT3/ADCY3/PRKD3/PDGFD/LPAR3/MAPK1/ITGB1/EVL/ADCY9	5.0341165856857
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	8/105	139/9376	5.13929427886263	FKBP5/FOS/PLCB1/AKT3/ADCY3/MAPK1/HSP90AB1/ADCY9	5.23221074958354
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	12/105	308/9376	3.47903525046382	MT-ND2/MT-ND3/MT-CYB/PLCB1/MT-CO2/MT-ND1/MT-CO3/MT-CO1/MT-ND4/HIP1/MT-ATP6/MT-ND5	4.70781406381058
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	6/105	75/9376	7.14361904761905	PLCB1/ADCY3/CGA/TG/HSPA5/ADCY9	5.68469390563393
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	13/105	368/9376	3.15445134575569	MT-ND2/MT-ND3/MT-CYB/MT-CO2/MT-ND1/MT-CO3/MT-CO1/MT-ND4/SRSF7/MT-ATP6/HSPA5/MT-ND5/PRKN	4.4870758255522
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	5/105	52/9376	8.58608058608059	ADCY3/CGA/FSHR/CYP19A1/ADCY9	5.83760880689498
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	5/105	59/9376	7.56739305891848	AKT3/ADCY3/CGA/PTGER3/ADCY9	5.38515198505352
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	7/105	130/9376	4.80820512820513	FOS/PLCB1/AKT3/ADCY3/MAPK1/ADCY9/COL4A4	4.65298939100926
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	9/105	217/9376	3.70348913759052	CCND3/RPS6KA2/FOS/AKT3/ADCY3/MAPK1/NOTCH2/HSP90AB1/ADCY9	4.28792779463477
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	5/105	65/9376	6.86886446886447	PLCB1/AKT3/CGA/MAPK1/KISS1	5.05277073030073
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	6/105	99/9376	5.41183261183261	FOS/AKT3/ADCY3/MAPK1/NOTCH2/ADCY9	4.69623523692094
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	11/105	333/9376	2.94969254969255	CCND3/HLA-C/ITGA1/AKT3/MAML2/EIF2AK2/MAPK1/ITGB1/NOTCH2/COL9A2/COL4A4	3.85521835191821
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	7/105	149/9376	4.19507829977629	PLCB1/AKT3/ADCY3/PDGFD/LPAR3/MAPK1/ADCY9	4.18370810763514
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	8/105	193/9376	3.70135701949173	PREX1/PLCB1/AKT3/ADCY3/CCL4/MAPK1/ADCY9/XCL2	4.03538843658946
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	6/105	110/9376	4.87064935064935	RPS6KA2/AKT3/ADCY3/MAPK1/HSP90AB1/ADCY9	4.34561273911094
NA	NA	hsa04518	Integrin signaling	7/105	154/9376	4.05887445887446	CCND3/ITGA1/AKT3/PDGFD/ITGB1/COL9A2/COL4A4	4.07311293467546
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	8/105	200/9376	3.57180952380952	FOS/WIPF3/MAPK1/ITGB1/TNFRSF10A/OCLN/MYO1F/ABI1	3.91240759063433
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	6/105	115/9376	4.65888198757764	FOS/PLCB1/AKT3/ADCY3/MAPK1/ADCY9	4.20131628409529
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	6/105	115/9376	4.65888198757764	FOS/PLCB1/ADCY3/MAPK1/RUNX2/ADCY9	4.20131628409529
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	8/105	203/9376	3.51902416138869	CCND3/ITGA1/AKT3/PDGFD/MAPK1/ITGB1/COL9A2/COL4A4	3.86137208381771
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	5/105	82/9376	5.44483159117306	HLA-C/KLRD1/HSPA5/KLRC1/HSP90AB1	4.30207423447549
Organismal Systems	Immune system	hsa04611	Platelet activation	6/105	126/9376	4.25215419501134	PLCB1/AKT3/ADCY3/MAPK1/ITGB1/ADCY9	3.91113252704873
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	5/105	87/9376	5.13191023535851	AREG/FOS/LEF1/AKT3/MAPK1	4.12043454995565
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	5/105	89/9376	5.01658640984484	ITGA1/CD44/ITGB1/COL9A2/COL4A4	4.05164505793036
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	5/105	89/9376	5.01658640984484	PLCB1/ADCY3/PDGFD/MAPK1/ADCY9	4.05164505793036
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	8/105	224/9376	3.1891156462585	CCND3/HLA-C/FOS/AKT3/ADCY3/MAPK1/IL2RA/ADCY9	3.5290003843036
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	8/105	226/9376	3.16089338390223	FOS/AKT3/ADCY3/CGA/PTGER3/FSHR/MAPK1/ADCY9	3.49940340075935
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	5/105	93/9376	4.80081925243216	FOS/MAML2/MAPK1/NOTCH2/IL2RA	3.92004916106642
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	5/105	93/9376	4.80081925243216	PLCB1/ADCY3/CGA/MAPK1/ADCY9	3.92004916106642
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	8/105	227/9376	3.14696874344451	HLA-C/PLCB1/AKT3/ADCY3/CCL4/PTGER3/MAPK1/ADCY9	3.4847275896856
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	6/105	138/9376	3.8824016563147	RPS6KA2/FOS/WIPF3/AKT3/MAPK1/ITGB1	3.6301290146094
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	5/105	97/9376	4.60284732449681	FOS/PLCB1/ADCY3/MAPK1/ADCY9	3.79575467563724
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	5/105	101/9376	4.42055634134842	LEF1/PLCB1/ADCY3/MAPK1/ADCY9	3.6780486821421
NA	NA	hsa04517	IgSF CAM signaling	9/105	299/9376	2.68781653129479	AKT3/SRGAP3/CASK/MAPK1/ROBO1/ITGB1/CD96/RASA1/TRIO	3.1565062958867
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	7/105	196/9376	3.1891156462585	HLA-C/FOS/LEF1/PREX1/AKT3/EIF2AK2/MAPK1	3.29603942116993
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	5/105	106/9376	4.21203953279425	LEF1/AKT3/PDGFD/MAPK1/HSP90AB1	3.53924758634117
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	5/105	110/9376	4.05887445887446	SMURF2/ID2/ACVR1B/MAPK1/DCN	3.43422578787611
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	7/105	205/9376	3.04910569105691	CCND3/HLA-C/RASA2/EIF2AK2/SP100/MAPK1/GTF2H2	3.1568208804055
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	4/105	71/9376	5.03071763916834	FOS/AKT3/CGA/MAPK1	3.62802573264176
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/105	157/9376	3.41255686988171	MT-CYB/FOS/MT-CO2/AKT3/MT-CO3/MT-CO1	3.24416157039692
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	7/105	216/9376	2.89382716049383	FOS/PLCB1/AKT3/MAPK1/HSPA5/TNFRSF10A/HSP90AB1	2.99665314018697
NA	NA	hsa04081	Hormone signaling	7/105	219/9376	2.85418569254186	CSH1/PLCB1/ADCY3/CGA/CSH2/FSHR/ADCY9	2.95471551843571
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/105	45/9376	5.95301587301587	HLA-C/KLRD1/KLRC1	3.54428697833031
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	6/105	180/9376	2.97650793650794	HLA-C/AKT3/SRSF5/EIF2AK2/SP100/SRSF7	2.84939285536363
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/105	87/9376	4.10552818828681	MT-CYB/MT-CO2/MT-CO3/MT-CO1	3.09690310631056
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/105	133/9376	3.35696383816685	HLA-C/KLRD1/MAPK1/KLRC1/TNFRSF10A	2.91332717949543
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	6/105	184/9376	2.91180124223603	SRGAP3/MAPK1/EPHA4/ROBO1/ITGB1/RASA1	2.78717116511314
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/105	134/9376	3.3319118692253	PLCB1/ADCY3/MAPK1/PLA2G6/ADCY9	2.89333384486745
Human Diseases	Infectious disease: viral	hsa05162	Measles	5/105	136/9376	3.28291316526611	CCND3/FOS/AKT3/EIF2AK2/IL2RA	2.85390727405121
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/105	300/9376	2.38120634920635	RPS6KA2/AREG/FOS/AKT3/RASA2/PDGFD/MAPK1/RASA1	2.58755117059894
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	4/105	93/9376	3.84065540194573	AKT3/ITGB1/FHIT/COL4A4	2.92976542311253
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/105	140/9376	3.1891156462585	PLCB1/AKT3/ADCY3/MAPK1/ADCY9	2.77720384543765
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	7/105	248/9376	2.52043010752688	FOS/LEF1/AKT3/MAPK1/TNFRSF10A/HSP90AB1/ABI1	2.58238792788108
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/105	54/9376	4.96084656084656	HLA-C/CGA/TG	3.10632825071031
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	4/105	98/9376	3.644703595724	PLCB1/ADCY3/PRKD3/ADCY9	2.80078554689654
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/105	99/9376	3.60788840788841	PLCB1/ADCY3/PLA2G6/ADCY9	2.77600229034887
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	4/105	99/9376	3.60788840788841	FOS/AKT3/PDGFD/MAPK1	2.77600229034887
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	5/105	148/9376	3.01673101673102	FOS/LEF1/AKT3/MAPK1/NOTCH2	2.63173429315464
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	4/105	100/9376	3.57180952380952	CCL4/TNFRSF10A/IL2RA/XCL2	2.75153744541659
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/105	100/9376	3.57180952380952	ITGA1/CD9/CD44/IL2RA	2.75153744541659
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/105	101/9376	3.53644507307874	PLCB1/AKT3/MAPK1/COL4A4	2.72738336322372
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/105	204/9376	2.62633053221289	CD44/AKT3/MAPK1/DCN/DDX5/ITGB1	2.49924523786742
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	3/105	59/9376	4.54043583535109	LEF1/AKT3/MAPK1	2.90309791048738
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/105	103/9376	3.46777623670827	FOS/PLCB1/AKT3/MAPK1	2.67997817679479
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	5/105	154/9376	2.89919604205318	PLCB1/AKT3/ADCY3/MAPK1/ADCY9	2.52891711260934
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	5/105	154/9376	2.89919604205318	FOS/PLCB1/ADCY3/MAPK1/ADCY9	2.52891711260934
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	2/105	24/9376	7.44126984126984	HS6ST2/XYLT1	3.36234181949743
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	5/105	155/9376	2.88049155145929	LEF1/PLCB1/ADCY3/MAPK1/ADCY9	2.51226369216685
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	4/105	105/9376	3.40172335600907	ITGA1/ADCY3/ITGB1/ADCY9	2.633730527457
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/105	157/9376	2.84379739156809	CCND3/HLA-C/AKT3/MAPK1/ZFP36L2	2.47935156099204
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	3/105	62/9376	4.32073732718894	AKT3/ADCY3/ADCY9	2.79176751235574
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/105	109/9376	3.27688947138488	FOS/AKT3/CCL4/MAPK1	2.54450092757103
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/105	109/9376	3.27688947138488	FOS/MAPK1/IL2RA/HSP90AB1	2.54450092757103
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	3/105	65/9376	4.12131868131868	PLCB1/ADCY3/ADCY9	2.68728435570082
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	5/105	166/9376	2.68961560527826	PLCB1/AKT3/ADCY3/MAPK1/ADCY9	2.33737900158674
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	3/105	67/9376	3.99829424307036	RPS6KA2/PLCB1/MAPK1	2.6210610354379
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/105	168/9376	2.65759637188209	CCND3/CSH1/AKT3/CSH2/IL2RA	2.30710717718898
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	3/105	68/9376	3.93949579831933	LEF1/AKT3/MAPK1	2.58890497450569
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	4/105	116/9376	3.07914614121511	PLCB1/ADCY3/MAPK1/ADCY9	2.39786934186911
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/105	173/9376	2.58078722818607	CCND3/AKT3/EIF2AK2/MAPK1/TNFRSF10A	2.23330869184819
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	6/105	232/9376	2.30935960591133	ITGA1/AKT3/PDGFD/MAPK1/ITGB1/PIP4K2A	2.14907622502234
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	4/105	122/9376	2.92771272443404	PLCB1/AKT3/MAPK1/NOTCH2	2.2807331711404
Human Diseases	Cancer: specific types	hsa05218	Melanoma	3/105	73/9376	3.66966731898239	AKT3/PDGFD/MAPK1	2.43682343053593
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	3/105	73/9376	3.66966731898239	AKT3/MAPK1/FHIT	2.43682343053593
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	7/105	298/9376	2.09753914988814	CSH1/CCL4/CSH2/ACVR1B/TNFRSF10A/IL2RA/XCL2	2.04903822730611
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	6/105	238/9376	2.25114045618247	AKT3/RASA2/PDGFD/MAPK1/PLA2G6/RASA1	2.08058741058199
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	4/105	125/9376	2.85744761904762	PLCB1/AKT3/MAPK1/ABCC1	2.22481671393824
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/105	76/9376	3.52481203007519	PLCB1/ADCY3/ADCY9	2.35185948078818
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/105	78/9376	3.43443223443223	FOS/MAPK1/ITGB1	2.29756188262183
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/105	78/9376	3.43443223443223	FOS/MAPK1/ITGB1	2.29756188262183
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/105	80/9376	3.34857142857143	AKT3/PDGFD/MAPK1	2.24500703553609
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/105	37/9376	4.82676962676963	LEF1/MAPK1	2.48198978532772
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/105	137/9376	2.60716023635732	FOS/AKT3/MAPK1/TNFRSF10A	2.01661956326535
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	4/105	138/9376	2.58826777087647	RPS6KA2/ADCY3/MAPK1/ADCY9	2.00028226648999
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	7/105	323/9376	1.93519091847265	DDIT4/CD44/ABCB1/MAPK1/HMOX1/NOTCH2/ABCC1	1.8202132815916
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/105	86/9376	3.11495016611296	AREG/AKT3/MAPK1	2.09680722556312
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/105	86/9376	3.11495016611296	PLCB1/ADCY3/ADCY9	2.09680722556312
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/105	86/9376	3.11495016611296	ITGA1/LEF1/ITGB1	2.09680722556312
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/105	142/9376	2.51535881958417	FOS/AKT3/HMOX1/HSP90AB1	1.93634043803906
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	3/105	89/9376	3.0099518459069	ADCY3/GPHN/ADCY9	2.0274956473453
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	4/105	144/9376	2.48042328042328	AKT3/ID2/ACVR1B/MAPK1	1.9051810420889
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/105	90/9376	2.97650793650794	AKT3/ADCY3/ADCY9	2.00503738556474
Organismal Systems	Digestive system	hsa04976	Bile secretion	3/105	90/9376	2.97650793650794	ADCY3/ABCB1/ADCY9	2.00503738556474
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/105	90/9376	2.97650793650794	FOS/AKT3/MAPK1	2.00503738556474
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	5/105	205/9376	2.17793263646922	CCND3/HLA-C/CD44/AKT3/EIF2AK2	1.81470499972071
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/105	91/9376	2.94379905808477	FOS/AKT3/MAPK1	1.98288764448934
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/105	93/9376	2.88049155145929	SMURF2/LEF1/MAPK1	1.93948168515864
Organismal Systems	Digestive system	hsa04970	Salivary secretion	3/105	93/9376	2.88049155145929	PLCB1/ADCY3/ADCY9	1.93948168515864
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/105	44/9376	4.05887445887446	ADCY3/ADCY9	2.16430081799291
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	4/105	150/9376	2.38120634920635	LEF1/AKT3/ABCB1/MAPK1	1.81474023286217
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/105	94/9376	2.84984802431611	FOS/MAPK1/HSP90AB1	1.91821018243648
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/105	45/9376	3.96867724867725	ABCB1/ABCC1	2.12433078857579
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/105	98/9376	2.733527696793	AKT3/MAPK1/PLA2G6	1.83583495941576
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/105	156/9376	2.28962148962149	AKT3/EIF2AK2/MAPK1/OCLN	1.72852671950514
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/105	157/9376	2.27503791325447	CCND3/AREG/LEF1/ID2	1.71454155158716
NA	NA	hsa03272	Virion - Hepatitis viruses	2/105	48/9376	3.72063492063492	CD9/OCLN	2.01100715280794
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	2/105	48/9376	3.72063492063492	PLCB1/AKT3	2.01100715280794
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	4/105	158/9376	2.26063893911995	RPS6KA2/DDIT4/AKT3/MAPK1	1.70066160292282
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	3/105	102/9376	2.62633053221289	PLCB1/ADCY3/ADCY9	1.7574879365073
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/105	51/9376	3.50177404295051	ADCY3/ADCY9	1.90645143802245
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/105	53/9376	3.3696316262354	PLCB1/ADCY9	1.84101754512548
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	5/105	233/9376	1.91620682607807	ITGA1/DCN/ITGB1/COL9A2/COL4A4	1.50710711777587
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	7/105	370/9376	1.68936936936937	CSH1/CGA/PTGER3/LPAR3/CSH2/FSHR/KISS1	1.43980564012462
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/105	170/9376	2.10106442577031	LEF1/AKT3/MAPK1/HMOX1	1.54176685119794
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/105	110/9376	2.43532467532468	AKT3/MAPK1/HMOX1	1.61145188540646
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/105	112/9376	2.39183673469388	AKT3/MAPK1/ITGB1	1.57693949355313
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/105	116/9376	2.30935960591133	TXK/ITGB1/OCLN	1.51007819713033
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/105	60/9376	2.97650793650794	AKT3/MAPK1	1.63446808556025
Organismal Systems	Nervous system	hsa04730	Long-term depression	2/105	60/9376	2.97650793650794	PLCB1/MAPK1	1.63446808556025
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/105	119/9376	2.25114045618247	FOS/AKT3/MAPK1	1.46171065745711
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/105	120/9376	2.23238095238095	RPS6KA2/AKT3/MAPK1	1.44590887858514
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	2/105	62/9376	2.88049155145929	MAML2/NOTCH2	1.58094263513086
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/105	253/9376	1.76472802559759	PLCB1/CD44/AKT3/MAPK1/ITGB1	1.31224651108897
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	5/105	254/9376	1.75778027746532	PLCB1/ADCY3/PTGER3/PDGFD/ADCY9	1.3029631082232
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/105	122/9376	2.19578454332553	FOS/AKT3/MAPK1	1.41476758384744
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	2/105	63/9376	2.83476946334089	PHYKPL/ACAT1	1.55497701502387
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	4/105	187/9376	1.9100585688821	PLCB1/TXNIP/MAPK1/HSP90AB1	1.33774401897152
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	3/105	128/9376	2.09285714285714	ADCY3/FHIT/ADCY9	1.3248340045186
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/105	17/9376	5.25266106442577	PCDH9	1.86761565304206
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/105	69/9376	2.58826777087647	AKT3/MAPK1	1.40916033085132
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/105	70/9376	2.5512925170068	AKT3/MAPK1	1.38636693126391
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/105	133/9376	2.01417830290011	FOS/PLCB1/AKT3	1.25357596363949
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/105	201/9376	1.77701966358683	ID2/DDX5/RUNX2/JMJD1C	1.18506998556252
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/105	71/9376	2.51535881958417	AKT3/MAPK1	1.36396574600333
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/105	75/9376	2.38120634920635	AKT3/MAPK1	1.2780309545396
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/105	75/9376	2.38120634920635	CCND3/TNFRSF10A	1.2780309545396
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/105	76/9376	2.34987468671679	AKT3/MAPK1	1.25740670672277
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/105	21/9376	4.25215419501134	XYLT1	1.58772717229304
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/105	142/9376	1.88651911468813	FOS/AKT3/MAPK1	1.13280286403471
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/105	77/9376	2.31935683364255	AKT3/MAPK1	1.23710484215489
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/105	77/9376	2.31935683364255	AKT3/MAPK1	1.23710484215489
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/105	78/9376	2.28962148962149	PLCB1/PIP4K2A	1.21711548822609
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/105	214/9376	1.66906987093903	HLA-C/FOS/AKT3/MAPK1	1.05365932155541
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/105	23/9376	3.8824016563147	ACAT1	1.47285484159376
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/105	26/9376	3.43443223443223	PLA2G6	1.32280417102512
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/105	26/9376	3.43443223443223	ABCC1	1.32280417102512
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/105	88/9376	2.02943722943723	CLU/TFPI	1.03251673709142
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	1/105	27/9376	3.30723104056437	ACAT1	1.27763672032541
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/105	160/9376	1.67428571428571	HLA-C/ITGB1/OCLN	0.915481798441906
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/105	28/9376	3.1891156462585	GPHN	1.23454056871824
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/105	91/9376	1.96253270538985	ADCY3/ADCY9	0.981888637612041
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/105	163/9376	1.64347063978966	FOS/AKT3/MAPK1	0.881939917313133
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/105	30/9376	2.97650793650794	PLA2G6	1.15388704853622
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/105	30/9376	2.97650793650794	ABCC1	1.15388704853622
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/105	168/9376	1.59455782312925	EIF2AK2/TNFRSF10A/HSP90AB1	0.827528730313201
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/105	169/9376	1.58512256973795	DDIT4/AKT3/MAPK1	0.816860937077725
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/105	31/9376	2.88049155145929	ACAT1	1.11603953080574
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/105	31/9376	2.88049155145929	HSPA5	1.11603953080574
NA	NA	hsa04981	Folate transport and metabolism	1/105	31/9376	2.88049155145929	ABCC1	1.11603953080574
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	2/105	98/9376	1.822351797862	PLCB1/PIP4K2A	0.87088437193498
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/105	99/9376	1.8039442039442	ITGA1/ITGB1	0.855769343776809
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/105	250/9376	1.42872380952381	SMURF2/HLA-C/WIPF3/IL2RA	0.731180115796511
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/105	174/9376	1.53957307060755	HSPA5/PRKN/HSP90AB1	0.764540987817068
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/105	103/9376	1.73388811835414	COL9A2/COL4A4	0.796994521683849
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/105	103/9376	1.73388811835414	PLCB1/COL4A4	0.796994521683849
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/105	178/9376	1.50497592295345	CCND3/LEF1/PLCB1	0.72385398119282
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/105	105/9376	1.70086167800454	SMURF2/PRKN	0.768565118987131
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/105	105/9376	1.70086167800454	AKT3/MAPK1	0.768565118987131
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/105	107/9376	1.66906987093903	PLCB1/AKT3	0.740736795563092
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/105	37/9376	2.41338481338481	PLCB1	0.916701816858447
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/105	109/9376	1.63844473569244	RPS6KA2/AKT3	0.713483567203712
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/105	38/9376	2.34987468671679	MAPK1	0.887309873415416
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/105	39/9376	2.28962148962149	HLA-C	0.858831337251681
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/105	115/9376	1.55296066252588	PLCB1/MAPK1	0.634937842713028
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/105	41/9376	2.17793263646922	MAPK1	0.804400291253703
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/105	195/9376	1.37377289377289	PLCB1/AKT3/MAPK1	0.561302675177462
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/105	42/9376	2.12607709750567	ACAT1	0.77835168490298
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/105	42/9376	2.12607709750567	HMOX1	0.77835168490298
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/105	43/9376	2.0766334440753	ACAT1	0.753023376596579
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/105	43/9376	2.0766334440753	ACAT1	0.753023376596579
NA	NA	hsa04082	Neuroactive ligand signaling	3/105	199/9376	1.34615936826992	PLCB1/ADCY3/ADCY9	0.525253867887803
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/105	44/9376	2.02943722943723	B4GALNT3	0.728376357937607
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/105	44/9376	2.02943722943723	GTF2H2	0.728376357937607
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/105	44/9376	2.02943722943723	HLA-C	0.728376357937607
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/105	122/9376	1.46385636221702	AKT3/TBC1D1	0.548801996554477
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/105	46/9376	1.94120082815735	HMOX1	0.680984758448689
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/105	47/9376	1.89989868287741	ACAT1	0.658175930044101
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/105	47/9376	1.89989868287741	MAPK1	0.658175930044101
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/105	48/9376	1.86031746031746	ACAT1	0.635919414715229
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/105	51/9376	1.75088702147526	PLA2G6	0.572205809680396
NA	NA	hsa04382	Cornified envelope formation	3/105	217/9376	1.23449637919684	S100A6/OCLN/COL4A4	0.371928086604224
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/105	133/9376	1.34278553526674	AKT3/MAPK1	0.423700355711519
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/105	52/9376	1.71721611721612	OSBPL5	0.551909128145841
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/105	138/9376	1.29413388543823	AKT3/MAPK1	0.370435518370571
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/105	56/9376	1.59455782312925	MGAT5	0.474894513764706
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/105	56/9376	1.59455782312925	SMURF2	0.474894513764706
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/105	142/9376	1.25767940979209	SMURF2/PRKN	0.329265290030365
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/105	57/9376	1.56658312447786	ACAT1	0.456597368502624
NA	NA	hsa04519	Cadherin signaling	5/105	404/9376	1.10513908533711	LEF1/PCDH9/MAPK1/EVL/MYO1F	0.229893790936265
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/105	144/9376	1.24021164021164	LEF1/AKT3	0.309132306328935
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/105	144/9376	1.24021164021164	PLCB1/AKT3	0.309132306328935
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/105	61/9376	1.46385636221702	HMOX1	0.386788900468385
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	3/105	238/9376	1.12557022809124	FOS/EIF2AK2/MAPK1	0.208817350937321
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/105	63/9376	1.41738473167045	PLA2G6	0.353735811030806
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/105	63/9376	1.41738473167045	GTF2H2	0.353735811030806
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/105	63/9376	1.41738473167045	LEF1	0.353735811030806
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/105	243/9376	1.10241034685479	SRSF5/SRSF7/DDX5	0.17213026692913
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/105	155/9376	1.15219662058372	HLA-C/ITGB1	0.203328775216379
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/105	66/9376	1.35295815295815	CYP19A1	0.306222672620386
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/105	157/9376	1.13751895662724	MAPK1/PLA2G6	0.184921532777396
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/105	69/9376	1.29413388543823	PLCB1	0.260964688019829
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/105	69/9376	1.29413388543823	FOS	0.260964688019829
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/105	70/9376	1.2756462585034	AKT3	0.246340940426301
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/105	70/9376	1.2756462585034	HLA-C	0.246340940426301
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/105	73/9376	1.2232224396608	ELL2	0.203753354329618
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/105	170/9376	1.05053221288515	ITGB1/OCLN	0.070757794839755
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/105	78/9376	1.14481074481074	CNOT7	0.136669093830349
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/105	78/9376	1.14481074481074	ITGB1	0.136669093830349
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/105	181/9376	0.986687713759537	AKT3/MAPK1	-0.0192456713419509
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/105	83/9376	1.0758462421113	CCL4	0.0738604829181633
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/105	86/9376	1.03831672203765	PLCB1	0.0379880249264236
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/105	194/9376	0.920569464899362	KIF26B/MYO1F	-0.118969793077199
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/105	95/9376	0.939949874686717	FOS	-0.06260302681013
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/105	104/9376	0.858608058608059	PLA2G6	-0.15430202051839
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/105	105/9376	0.850430839002268	CCL4	-0.164017585247804
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/105	116/9376	0.769786535303777	ACAT1	-0.265504092347219
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/105	154/9376	0.579839208410637	GPHN	-0.559474531522888
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/105	158/9376	0.565159734779988	CCND3	-0.586620101534151
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/105	191/9376	0.467514335577163	MAPK1	-0.791228679568921
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/105	250/9376	0.357180952380952	OSBPL5	-1.09631537888309
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/105	449/9376	0.198875808675363	ADCY3	-1.85134452685539