ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/187 68/18639 0.132352941176471 13.1921201635734 2.51394222993268e-08 1.37261245754324e-05 GO:0009055 electron transfer activity 10/187 116/18639 0.0862068965517241 8.59256868891757 2.64040071399402e-07 7.20829394920366e-05 GO:0015399 primary active transmembrane transporter activity 11/187 166/18639 0.0662650602409639 6.60489014883062 9.43804904857081e-07 0.000171772492683989 GO:0022853 active monoatomic ion transmembrane transporter activity 9/187 118/18639 0.076271186440678 7.60223873833046 2.96641575469162e-06 0.000404915750515406 GO:0015078 proton transmembrane transporter activity 10/187 185/18639 0.0540540540540541 5.38777279953751 1.80206577463125e-05 0.00196785582589733 GO:0008137 NADH dehydrogenase (ubiquinone) activity 5/187 41/18639 0.121951219512195 12.1553410721273 5.38626494095525e-05 0.00490150109626927 GO:0003954 NADH dehydrogenase activity 5/187 44/18639 0.113636363636364 11.3265678172095 7.61794925665099e-05 0.00594200042018777 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/187 58/18639 0.0862068965517241 8.59256868891757 0.000286966876363527 0.0195854893118107 GO:0004129 cytochrome-c oxidase activity 3/187 15/18639 0.2 19.9347593582888 0.000413716162654029 0.0250987805343444 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/187 16/18639 0.1875 18.6888368983957 0.000505439362542159 0.0275969891948019 GO:0046332 SMAD binding 5/187 79/18639 0.0632911392405063 6.30846815135721 0.00119149437510035 0.0591414480731629 GO:0005201 extracellular matrix structural constituent 7/187 168/18639 0.0416666666666667 4.15307486631016 0.00155609731571962 0.0708024278652427 GO:0005096 GTPase activator activity 9/187 271/18639 0.033210332103321 3.31019989344278 0.00170348636942705 0.071546427515936 GO:0016651 oxidoreductase activity, acting on NAD(P)H 5/187 88/18639 0.0568181818181818 5.66328390860476 0.00192652711148286 0.0751345573478316 GO:0070412 R-SMAD binding 3/187 26/18639 0.115384615384615 11.5008227067051 0.00217990354483072 0.0780589654928174 GO:0022804 active transmembrane transporter activity 12/187 457/18639 0.0262582056892779 2.61725505798102 0.00228744221224373 0.0780589654928174 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/187 349/18639 0.0286532951289398 2.85598271608722 0.00282927953908314 0.0908698016670232 GO:0031625 ubiquitin protein ligase binding 9/187 302/18639 0.0298013245033113 2.97041116265892 0.00351882593744919 0.100350713509809 GO:0140297 DNA-binding transcription factor binding 12/187 488/18639 0.0245901639344262 2.45099500306829 0.00388472066483759 0.100350713509809 GO:0030695 GTPase regulator activity 12/187 489/18639 0.0245398773006135 2.44598274334832 0.00394828526426559 0.100350713509809 GO:0060589 nucleoside-triphosphatase regulator activity 12/187 490/18639 0.0244897959183673 2.44099094183128 0.004012685661575 0.100350713509809 GO:0005131 growth hormone receptor binding 2/187 10/18639 0.2 19.9347593582888 0.00427308014452888 0.100350713509809 GO:0019887 protein kinase regulator activity 8/187 255/18639 0.0313725490196078 3.12702107581 0.00429747997436552 0.100350713509809 GO:1990841 promoter-specific chromatin binding 4/187 68/18639 0.0588235294117647 5.86316451714376 0.00484695954562822 0.100350713509809 GO:0004222 metalloendopeptidase activity 5/187 110/18639 0.0454545454545455 4.53062712688381 0.00504617941372594 0.100350713509809 GO:0005154 epidermal growth factor receptor binding 3/187 35/18639 0.0857142857142857 8.54346829640947 0.00513676454144729 0.100350713509809 GO:0004016 adenylate cyclase activity 2/187 11/18639 0.181818181818182 18.1225085075352 0.0051883121273139 0.100350713509809 GO:0003779 actin binding 11/187 443/18639 0.0248306997742664 2.47497012348958 0.00523259791079637 0.100350713509809 GO:0044389 ubiquitin-like protein ligase binding 9/187 322/18639 0.0279503105590062 2.78591357491613 0.00532998295198617 0.100350713509809 GO:0023023 MHC protein complex binding 3/187 37/18639 0.0810810810810811 8.08165919930626 0.00600957789539837 0.107088478722066 GO:0017124 SH3 domain binding 5/187 115/18639 0.0434782608695652 4.33364333875843 0.00608011509227845 0.107088478722066 GO:0019208 phosphatase regulator activity 5/187 117/18639 0.0427350427350427 4.25956396544632 0.0065325757018326 0.111462072912519 GO:0003725 double-stranded RNA binding 4/187 75/18639 0.0533333333333333 5.31593582887701 0.00685320483728228 0.113389389125943 GO:0008559 ABC-type xenobiotic transporter activity 2/187 14/18639 0.142857142857143 14.2391138273491 0.0084163422424071 0.129942137316696 GO:0042043 neurexin family protein binding 2/187 14/18639 0.142857142857143 14.2391138273491 0.0084163422424071 0.129942137316696 GO:0019207 kinase regulator activity 8/187 287/18639 0.0278745644599303 2.7783636736291 0.00856761344945249 0.129942137316696 GO:0048156 tau protein binding 3/187 43/18639 0.0697674418604651 6.95398582265887 0.00913566044433629 0.134812718989395 GO:0031072 heat shock protein binding 5/187 131/18639 0.0381679389312977 3.80434338898641 0.0103791839469949 0.149132485133137 GO:0005521 lamin binding 2/187 16/18639 0.125 12.4592245989305 0.0109535263601466 0.149515634816001 GO:0015562 efflux transmembrane transporter activity 2/187 16/18639 0.125 12.4592245989305 0.0109535263601466 0.149515634816001 GO:0051087 protein-folding chaperone binding 5/187 134/18639 0.0373134328358209 3.7191715220688 0.0113694141222712 0.151407319774637 GO:0004674 protein serine/threonine kinase activity 10/187 433/18639 0.023094688221709 2.30193526077238 0.0122651093459448 0.154148265042662 GO:0051787 misfolded protein binding 2/187 17/18639 0.117647058823529 11.7263290342875 0.0123327658529733 0.154148265042662 GO:0016922 nuclear receptor binding 5/187 137/18639 0.0364963503649635 3.63772980990671 0.0124222045089325 0.154148265042662 GO:0004713 protein tyrosine kinase activity 5/187 140/18639 0.0357142857142857 3.55977845683728 0.0135392429472366 0.164276147759805 GO:0046624 sphingolipid transporter activity 2/187 19/18639 0.105263157894737 10.4919786096257 0.0153046165691669 0.181659144494894 GO:0015631 tubulin binding 9/187 385/18639 0.0233766233766234 2.33003680811167 0.0159364401745185 0.185133964580576 GO:0005516 calmodulin binding 6/187 207/18639 0.0289855072463768 2.88909555917229 0.0182632585568785 0.206707563036118 GO:0009975 cyclase activity 2/187 21/18639 0.0952380952380952 9.49274255156608 0.0185506787340106 0.206707563036118 GO:0016849 phosphorus-oxygen lyase activity 2/187 23/18639 0.0869565217391304 8.66728667751686 0.022058939315809 0.23616040914572 GO:0140103 catalytic activity, acting on a glycoprotein 2/187 23/18639 0.0869565217391304 8.66728667751686 0.022058939315809 0.23616040914572 GO:0008083 growth factor activity 5/187 162/18639 0.0308641975308642 3.07635175282234 0.0238386691695235 0.250306026279997 GO:0019211 phosphatase activator activity 2/187 25/18639 0.08 7.97390374331551 0.0258177512117782 0.256413533234999 GO:0141003 histone H2AX kinase activity 8/187 354/18639 0.0225988700564972 2.25251518172754 0.0267656583858393 0.256413533234999 GO:0004435 phosphatidylinositol phospholipase C activity 2/187 26/18639 0.0769230769230769 7.66721513780337 0.0277875718506905 0.256413533234999 GO:0008198 ferrous iron binding 2/187 26/18639 0.0769230769230769 7.66721513780337 0.0277875718506905 0.256413533234999 GO:0050681 nuclear androgen receptor binding 2/187 26/18639 0.0769230769230769 7.66721513780337 0.0277875718506905 0.256413533234999 GO:0140996 histone H3 kinase activity 8/187 357/18639 0.0224089635854342 2.23358648272143 0.0279504531368584 0.256413533234999 GO:0001221 transcription coregulator binding 4/187 115/18639 0.0347826086956522 3.46691467100674 0.0286913414476325 0.256413533234999 GO:0035401 histone H3Y41 kinase activity 4/187 115/18639 0.0347826086956522 3.46691467100674 0.0286913414476325 0.256413533234999 GO:0140801 histone H2AXY142 kinase activity 4/187 115/18639 0.0347826086956522 3.46691467100674 0.0286913414476325 0.256413533234999 GO:0035173 histone kinase activity 8/187 360/18639 0.0222222222222222 2.21497326203209 0.0291711953507301 0.256413533234999 GO:0106310 protein serine kinase activity 8/187 361/18639 0.0221606648199446 2.20883760202646 0.0295861769117306 0.256413533234999 GO:0046966 nuclear thyroid hormone receptor binding 2/187 28/18639 0.0714285714285714 7.11955691367456 0.0319011490679143 0.272156677985644 GO:0051082 unfolded protein binding 4/187 121/18639 0.0330578512396694 3.29500154682459 0.0336860252233762 0.281621937651514 GO:0004629 phospholipase C activity 2/187 29/18639 0.0689655172413793 6.87405495113406 0.0340422122435896 0.281621937651514 GO:0005518 collagen binding 3/187 72/18639 0.0416666666666667 4.15307486631016 0.035789147805649 0.286750477751584 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/187 30/18639 0.0666666666666667 6.64491978609626 0.0362376977378376 0.286750477751584 GO:0070566 adenylyltransferase activity 2/187 30/18639 0.0666666666666667 6.64491978609626 0.0362376977378376 0.286750477751584 GO:0008237 metallopeptidase activity 5/187 184/18639 0.0271739130434783 2.70852708672402 0.0381917029786819 0.297281696358397 GO:0033218 amide binding 6/187 247/18639 0.0242914979757085 2.42122583299054 0.0386575099660187 0.297281696358397 GO:0042910 xenobiotic transmembrane transporter activity 2/187 32/18639 0.0625 6.22961229946524 0.040786776703815 0.309299723337264 GO:0030296 protein tyrosine kinase activator activity 2/187 33/18639 0.0606060606060606 6.04083616917842 0.0431378410559714 0.316689152457681 GO:0140416 transcription regulator inhibitor activity 2/187 33/18639 0.0606060606060606 6.04083616917842 0.0431378410559714 0.316689152457681 GO:0019199 transmembrane receptor protein kinase activity 3/187 78/18639 0.0384615384615385 3.83360756890169 0.0437291592448483 0.316689152457681 GO:0005179 hormone activity 4/187 132/18639 0.0303030303030303 3.02041808458921 0.0440812739684685 0.316689152457681 GO:0051427 hormone receptor binding 2/187 34/18639 0.0588235294117647 5.86316451714376 0.0455382689458749 0.322907725252568 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/187 36/18639 0.0555555555555556 5.53743315508021 0.0504823729132083 0.339001255266106 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/187 36/18639 0.0555555555555556 5.53743315508021 0.0504823729132083 0.339001255266106 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/187 36/18639 0.0555555555555556 5.53743315508021 0.0504823729132083 0.339001255266106 GO:0001540 amyloid-beta binding 3/187 83/18639 0.036144578313253 3.60266735390761 0.0509589592384861 0.339001255266106 GO:0030295 protein kinase activator activity 4/187 139/18639 0.0287769784172662 2.86831069903436 0.0515331578518073 0.339001255266106 GO:0070851 growth factor receptor binding 4/187 139/18639 0.0287769784172662 2.86831069903436 0.0515331578518073 0.339001255266106 GO:0004860 protein kinase inhibitor activity 3/187 84/18639 0.0357142857142857 3.55977845683728 0.0524703803160057 0.341057472054037 GO:0003714 transcription corepressor activity 5/187 204/18639 0.0245098039215686 2.44298521547656 0.0550214489125967 0.353431895367974 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/187 39/18639 0.0512820512820513 5.11147675853558 0.0582389884698243 0.357719413394897 GO:0030331 nuclear estrogen receptor binding 2/187 40/18639 0.05 4.98368983957219 0.0609107366540113 0.357719413394897 GO:0140662 ATP-dependent protein folding chaperone 2/187 40/18639 0.05 4.98368983957219 0.0609107366540113 0.357719413394897 GO:0019210 kinase inhibitor activity 3/187 90/18639 0.0333333333333333 3.32245989304813 0.0619855743600117 0.357719413394897 GO:0019209 kinase activator activity 4/187 148/18639 0.027027027027027 2.69388639976875 0.0620624630531379 0.357719413394897 GO:0003712 transcription coregulator activity 9/187 495/18639 0.0181818181818182 1.81225085075352 0.0623380560210966 0.357719413394897 GO:0005543 phospholipid binding 9/187 497/18639 0.0181086519114688 1.80495809079073 0.063597471000936 0.357719413394897 GO:0043178 alcohol binding 3/187 92/18639 0.0326086956521739 3.25023250406882 0.0653238556531398 0.357719413394897 GO:0016859 cis-trans isomerase activity 2/187 42/18639 0.0476190476190476 4.74637127578304 0.0663768956297208 0.357719413394897 GO:0051213 dioxygenase activity 3/187 93/18639 0.032258064516129 3.21528376746593 0.0670235109563081 0.357719413394897 GO:0051219 phosphoprotein binding 3/187 93/18639 0.032258064516129 3.21528376746593 0.0670235109563081 0.357719413394897 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/187 43/18639 0.0465116279069767 4.63599054843925 0.0691691510046176 0.357719413394897 GO:0001046 core promoter sequence-specific DNA binding 2/187 44/18639 0.0454545454545455 4.53062712688381 0.071999448853375 0.357719413394897 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/187 44/18639 0.0454545454545455 4.53062712688381 0.071999448853375 0.357719413394897 GO:0043014 alpha-tubulin binding 2/187 44/18639 0.0454545454545455 4.53062712688381 0.071999448853375 0.357719413394897 GO:0140375 immune receptor activity 4/187 156/18639 0.0256410256410256 2.55573837926779 0.0723018976063128 0.357719413394897 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/187 45/18639 0.0444444444444444 4.42994652406417 0.0748667543548632 0.357719413394897 GO:0008009 chemokine activity 2/187 45/18639 0.0444444444444444 4.42994652406417 0.0748667543548632 0.357719413394897 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/187 46/18639 0.0434782608695652 4.33364333875843 0.0777700494231163 0.357719413394897 GO:0030291 protein serine/threonine kinase inhibitor activity 2/187 46/18639 0.0434782608695652 4.33364333875843 0.0777700494231163 0.357719413394897 GO:0001784 phosphotyrosine residue binding 2/187 47/18639 0.0425531914893617 4.24143816133804 0.0807083324786922 0.357719413394897 GO:0140359 ABC-type transporter activity 2/187 47/18639 0.0425531914893617 4.24143816133804 0.0807083324786922 0.357719413394897 GO:0005085 guanyl-nucleotide exchange factor activity 5/187 230/18639 0.0217391304347826 2.16682166937921 0.0823896564632647 0.357719413394897 GO:0001222 transcription corepressor binding 2/187 49/18639 0.0408163265306122 4.06831823638546 0.0866859374148363 0.357719413394897 GO:0016763 pentosyltransferase activity 2/187 49/18639 0.0408163265306122 4.06831823638546 0.0866859374148363 0.357719413394897 GO:0035254 glutamate receptor binding 2/187 49/18639 0.0408163265306122 4.06831823638546 0.0866859374148363 0.357719413394897 GO:0005006 epidermal growth factor receptor activity 2/187 50/18639 0.04 3.98695187165775 0.0897233366512705 0.357719413394897 GO:0048020 CCR chemokine receptor binding 2/187 50/18639 0.04 3.98695187165775 0.0897233366512705 0.357719413394897 GO:0030544 Hsp70 protein binding 2/187 51/18639 0.0392156862745098 3.9087763447625 0.0927918781492233 0.357719413394897 GO:0019888 protein phosphatase regulator activity 3/187 107/18639 0.0280373831775701 2.79459243340497 0.0928510858328531 0.357719413394897 GO:0004955 prostaglandin receptor activity 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0005522 profilin binding 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0005528 FK506 binding 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0019911 structural constituent of myelin sheath 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0042975 peroxisome proliferator activated receptor binding 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0140940 histone H2A methyltransferase activity 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:1990259 histone H2AQ104 methyltransferase activity 1/187 10/18639 0.1 9.96737967914439 0.0959389758827129 0.357719413394897 GO:0004620 phospholipase activity 3/187 109/18639 0.0275229357798165 2.74331550802139 0.0968337043066692 0.357719413394897 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/187 243/18639 0.0205761316872428 2.05090116854823 0.0983478908697311 0.357719413394897 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0004711 ribosomal protein S6 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0035175 histone H3S10 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0035979 histone H2AXS139 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0044022 histone H3S28 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0044023 histone H4S1 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0044024 histone H2AS1 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0044025 histone H2BS14 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0072354 histone H3T3 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0072371 histone H2AS121 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0140823 histone H2BS36 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0140855 histone H3S57 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0140995 histone H2A kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0140997 histone H4 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0140998 histone H2B kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:1990244 histone H2AT120 kinase activity 5/187 245/18639 0.0204081632653061 2.03415911819273 0.10093282473436 0.357719413394897 GO:0015485 cholesterol binding 2/187 54/18639 0.037037037037037 3.69162210338681 0.102175208197488 0.357719413394897 GO:0004677 DNA-dependent protein kinase activity 5/187 246/18639 0.0203252032520325 2.02589017868788 0.102238026723783 0.357719413394897 GO:0140857 histone H3T45 kinase activity 5/187 246/18639 0.0203252032520325 2.02589017868788 0.102238026723783 0.357719413394897 GO:0035402 histone H3T11 kinase activity 5/187 247/18639 0.0202429149797571 2.01768819415878 0.103551673764233 0.357719413394897 GO:0035403 histone H3T6 kinase activity 5/187 247/18639 0.0202429149797571 2.01768819415878 0.103551673764233 0.357719413394897 GO:0005319 lipid transporter activity 4/187 178/18639 0.0224719101123595 2.23986060205492 0.104529172480168 0.357719413394897 GO:0004679 AMP-activated protein kinase activity 5/187 248/18639 0.0201612903225806 2.00955235466621 0.104873731308895 0.357719413394897 GO:0002162 dystroglycan binding 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0004954 prostanoid receptor activity 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0008046 axon guidance receptor activity 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0019107 myristoyltransferase activity 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0035252 UDP-xylosyltransferase activity 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0042285 xylosyltransferase activity 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0048185 activin binding 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0070990 snRNP binding 1/187 11/18639 0.0909090909090909 9.06125425376762 0.105014042258252 0.357719413394897 GO:0042277 peptide binding 5/187 249/18639 0.0200803212851406 2.00148186328201 0.106204164175209 0.357719413394897 GO:0000340 RNA 7-methylguanosine cap binding 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0005025 transforming growth factor beta receptor activity, type I 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0005026 transforming growth factor beta receptor activity, type II 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0005527 macrolide binding 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0016273 arginine N-methyltransferase activity 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0016274 protein-arginine N-methyltransferase activity 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0016361 activin receptor activity, type I 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0016362 activin receptor activity, type II 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0017002 activin receptor activity 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0035197 siRNA binding 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0036009 protein-glutamine N-methyltransferase activity 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0045295 gamma-catenin binding 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0070679 inositol 1,4,5 trisphosphate binding 1/187 12/18639 0.0833333333333333 8.30614973262032 0.113998494378594 0.357719413394897 GO:0061980 regulatory RNA binding 2/187 58/18639 0.0344827586206897 3.43702747556703 0.115068060507934 0.358821950725408 GO:0045309 protein phosphorylated amino acid binding 2/187 59/18639 0.0338983050847458 3.37877277259132 0.118353784737957 0.358821950725408 GO:0140597 protein carrier chaperone 4/187 188/18639 0.0212765957446809 2.12071908066902 0.121015234974874 0.358821950725408 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/187 60/18639 0.0333333333333333 3.32245989304813 0.121662879552056 0.358821950725408 GO:0004535 poly(A)-specific ribonuclease activity 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0005035 death receptor activity 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0030955 potassium ion binding 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0035673 oligopeptide transmembrane transporter activity 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0070123 transforming growth factor beta receptor activity, type III 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0140333 glycerophospholipid flippase activity 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0140666 annealing activity 1/187 13/18639 0.0769230769230769 7.66721513780337 0.122893232208153 0.358821950725408 GO:0004857 enzyme inhibitor activity 7/187 416/18639 0.0168269230769231 1.67720331139449 0.126143206658537 0.365078672814552 GO:0016757 glycosyltransferase activity 5/187 267/18639 0.0187265917602996 1.86655050171243 0.131540433035954 0.365078672814552 GO:0004705 JUN kinase activity 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0005161 platelet-derived growth factor receptor binding 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0032454 histone H3K9 demethylase activity 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0044548 S100 protein binding 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0070742 C2H2 zinc finger domain binding 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0098821 BMP receptor activity 1/187 14/18639 0.0714285714285714 7.11955691367456 0.131699146820902 0.365078672814552 GO:0005507 copper ion binding 2/187 63/18639 0.0317460317460317 3.16424751718869 0.131722524806716 0.365078672814552 GO:0042826 histone deacetylase binding 3/187 127/18639 0.0236220472440945 2.35449913680576 0.135569390557558 0.369910102784269 GO:0031490 chromatin DNA binding 3/187 128/18639 0.0234375 2.33610461229947 0.137860292875889 0.369910102784269 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/187 128/18639 0.0234375 2.33610461229947 0.137860292875889 0.369910102784269 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/187 15/18639 0.0666666666666667 6.64491978609626 0.140417120487721 0.369910102784269 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/187 15/18639 0.0666666666666667 6.64491978609626 0.140417120487721 0.369910102784269 GO:0004953 icosanoid receptor activity 1/187 15/18639 0.0666666666666667 6.64491978609626 0.140417120487721 0.369910102784269 GO:0005523 tropomyosin binding 1/187 15/18639 0.0666666666666667 6.64491978609626 0.140417120487721 0.369910102784269 GO:0034483 heparan sulfate sulfotransferase activity 1/187 15/18639 0.0666666666666667 6.64491978609626 0.140417120487721 0.369910102784269 GO:0016298 lipase activity 3/187 130/18639 0.0230769230769231 2.30016454134101 0.142481578816125 0.369910102784269 GO:0005126 cytokine receptor binding 5/187 275/18639 0.0181818181818182 1.81225085075352 0.143605939788029 0.369910102784269 GO:0008017 microtubule binding 5/187 276/18639 0.0181159420289855 1.80568472448268 0.145147104050921 0.369910102784269 GO:0016500 protein-hormone receptor activity 2/187 67/18639 0.0298507462686567 2.97533721765504 0.145415977024736 0.369910102784269 GO:0050840 extracellular matrix binding 2/187 67/18639 0.0298507462686567 2.97533721765504 0.145415977024736 0.369910102784269 GO:0005548 phospholipid transporter activity 2/187 68/18639 0.0294117647058824 2.93158225857188 0.14888459281454 0.369910102784269 GO:0032934 sterol binding 2/187 68/18639 0.0294117647058824 2.93158225857188 0.14888459281454 0.369910102784269 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0004707 MAP kinase activity 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0005024 transforming growth factor beta receptor activity 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0008142 oxysterol binding 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0030275 LRR domain binding 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0070411 I-SMAD binding 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0140327 flippase activity 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0140328 floppase activity 1/187 16/18639 0.0625 6.22961229946524 0.149048026762892 0.369910102784269 GO:0002020 protease binding 3/187 136/18639 0.0220588235294118 2.19868669392891 0.156646179347008 0.380732880049073 GO:0016779 nucleotidyltransferase activity 3/187 136/18639 0.0220588235294118 2.19868669392891 0.156646179347008 0.380732880049073 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/187 17/18639 0.0588235294117647 5.86316451714376 0.157592730569763 0.380732880049073 GO:0045125 bioactive lipid receptor activity 1/187 17/18639 0.0588235294117647 5.86316451714376 0.157592730569763 0.380732880049073 GO:0048038 quinone binding 1/187 17/18639 0.0588235294117647 5.86316451714376 0.157592730569763 0.380732880049073 GO:1990226 histone methyltransferase binding 1/187 17/18639 0.0588235294117647 5.86316451714376 0.157592730569763 0.380732880049073 GO:0051015 actin filament binding 4/187 209/18639 0.0191387559808612 1.90763247447739 0.158919333517795 0.382246502646327 GO:0008094 ATP-dependent activity, acting on DNA 4/187 210/18639 0.019047619047619 1.89854851031322 0.160824792121958 0.385126160689085 GO:0042379 chemokine receptor binding 2/187 72/18639 0.0277777777777778 2.76871657754011 0.162919337396881 0.385126160689085 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/187 18/18639 0.0555555555555556 5.53743315508021 0.166052088285553 0.385126160689085 GO:0008525 phosphatidylcholine transporter activity 1/187 18/18639 0.0555555555555556 5.53743315508021 0.166052088285553 0.385126160689085 GO:0035615 clathrin adaptor activity 1/187 18/18639 0.0555555555555556 5.53743315508021 0.166052088285553 0.385126160689085 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/187 18/18639 0.0555555555555556 5.53743315508021 0.166052088285553 0.385126160689085 GO:0050811 GABA receptor binding 1/187 18/18639 0.0555555555555556 5.53743315508021 0.166052088285553 0.385126160689085 GO:1990381 ubiquitin-specific protease binding 1/187 18/18639 0.0555555555555556 5.53743315508021 0.166052088285553 0.385126160689085 GO:0043539 protein serine/threonine kinase activator activity 2/187 73/18639 0.0273972602739726 2.73078895319024 0.166464787404073 0.385126160689085 GO:0020037 heme binding 3/187 142/18639 0.0211267605633803 2.10578443925586 0.171226765694131 0.393541791374555 GO:0044183 protein folding chaperone 2/187 75/18639 0.0266666666666667 2.6579679144385 0.173595335617396 0.393541791374555 GO:0008301 DNA binding, bending 1/187 19/18639 0.0526315789473684 5.24598930481283 0.174426947825352 0.393541791374555 GO:0031420 alkali metal ion binding 1/187 19/18639 0.0526315789473684 5.24598930481283 0.174426947825352 0.393541791374555 GO:0034987 immunoglobulin receptor binding 1/187 19/18639 0.0526315789473684 5.24598930481283 0.174426947825352 0.393541791374555 GO:0050145 nucleoside monophosphate kinase activity 1/187 19/18639 0.0526315789473684 5.24598930481283 0.174426947825352 0.393541791374555 GO:0098631 cell adhesion mediator activity 2/187 76/18639 0.0263157894736842 2.62299465240642 0.177179201866991 0.398106354812251 GO:0008194 UDP-glycosyltransferase activity 3/187 145/18639 0.0206896551724138 2.06221648534022 0.178659038924969 0.399786210053415 GO:0000339 RNA cap binding 1/187 20/18639 0.05 4.98368983957219 0.18271814872528 0.403903276129567 GO:0016408 C-acyltransferase activity 1/187 20/18639 0.05 4.98368983957219 0.18271814872528 0.403903276129567 GO:0140939 histone H4 methyltransferase activity 1/187 20/18639 0.05 4.98368983957219 0.18271814872528 0.403903276129567 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0051010 microtubule plus-end binding 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0070182 DNA polymerase binding 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0072542 protein phosphatase activator activity 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0140312 cargo adaptor activity 1/187 21/18639 0.0476190476190476 4.74637127578304 0.190926522224844 0.408508946047411 GO:0048306 calcium-dependent protein binding 2/187 80/18639 0.025 2.4918449197861 0.191624746024682 0.408508946047411 GO:0000510 H3-H4 histone complex chaperone activity 3/187 151/18639 0.0198675496688742 1.98027410843928 0.193779884663516 0.408508946047411 GO:0140584 chromatin extrusion motor activity 3/187 151/18639 0.0198675496688742 1.98027410843928 0.193779884663516 0.408508946047411 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/187 151/18639 0.0198675496688742 1.98027410843928 0.193779884663516 0.408508946047411 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/187 151/18639 0.0198675496688742 1.98027410843928 0.193779884663516 0.408508946047411 GO:0015616 DNA translocase activity 3/187 152/18639 0.0197368421052632 1.96724598930481 0.196330890322881 0.409147580596539 GO:0046906 tetrapyrrole binding 3/187 152/18639 0.0197368421052632 1.96724598930481 0.196330890322881 0.409147580596539 GO:0140674 ATP-dependent histone chaperone activity 3/187 152/18639 0.0197368421052632 1.96724598930481 0.196330890322881 0.409147580596539 GO:0061775 cohesin loader activity 3/187 153/18639 0.0196078431372549 1.95438817238125 0.198890180851603 0.411677570743457 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/187 22/18639 0.0454545454545455 4.53062712688381 0.199052891348485 0.411677570743457 GO:0005506 iron ion binding 3/187 154/18639 0.0194805194805195 1.94169734009306 0.20145755802347 0.415078591248358 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/187 23/18639 0.0434782608695652 4.33364333875843 0.207098070986334 0.420355192410924 GO:0005212 structural constituent of eye lens 1/187 23/18639 0.0434782608695652 4.33364333875843 0.207098070986334 0.420355192410924 GO:0043274 phospholipase binding 1/187 23/18639 0.0434782608695652 4.33364333875843 0.207098070986334 0.420355192410924 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/187 23/18639 0.0434782608695652 4.33364333875843 0.207098070986334 0.420355192410924 GO:0005125 cytokine activity 4/187 234/18639 0.0170940170940171 1.70382558617853 0.20885818371199 0.422357660395357 GO:0140658 ATP-dependent chromatin remodeler activity 3/187 158/18639 0.0189873417721519 1.89254044540716 0.211804000156891 0.422672403889727 GO:0004622 lysophospholipase activity 1/187 24/18639 0.0416666666666667 4.15307486631016 0.21506286797417 0.422672403889727 GO:0005540 hyaluronic acid binding 1/187 24/18639 0.0416666666666667 4.15307486631016 0.21506286797417 0.422672403889727 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/187 24/18639 0.0416666666666667 4.15307486631016 0.21506286797417 0.422672403889727 GO:0035035 histone acetyltransferase binding 1/187 24/18639 0.0416666666666667 4.15307486631016 0.21506286797417 0.422672403889727 GO:0070840 dynein complex binding 1/187 24/18639 0.0416666666666667 4.15307486631016 0.21506286797417 0.422672403889727 GO:0003689 DNA clamp loader activity 3/187 160/18639 0.01875 1.86888368983957 0.217020654601369 0.422672403889727 GO:0008081 phosphoric diester hydrolase activity 2/187 87/18639 0.0229885057471264 2.29135165037802 0.217242302805623 0.422672403889727 GO:0005178 integrin binding 3/187 161/18639 0.0186335403726708 1.85727571661075 0.21963916537202 0.422672403889727 GO:0004175 endopeptidase activity 6/187 405/18639 0.0148148148148148 1.47664884135472 0.222409356013608 0.422672403889727 GO:0000030 mannosyltransferase activity 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0008483 transaminase activity 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0019707 protein-cysteine S-acyltransferase activity 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0042974 nuclear retinoic acid receptor binding 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0047617 fatty acyl-CoA hydrolase activity 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/187 25/18639 0.04 3.98695187165775 0.222948081172603 0.422672403889727 GO:0003727 single-stranded RNA binding 2/187 89/18639 0.0224719101123595 2.23986060205492 0.22462016710023 0.424368897012891 GO:0140713 histone chaperone activity 3/187 164/18639 0.0182926829268293 1.82330116081909 0.22753314911331 0.427091382521464 GO:0016289 acyl-CoA hydrolase activity 1/187 26/18639 0.0384615384615385 3.83360756890169 0.23075450154548 0.427091382521464 GO:0043548 phosphatidylinositol 3-kinase binding 1/187 26/18639 0.0384615384615385 3.83360756890169 0.23075450154548 0.427091382521464 GO:0050750 low-density lipoprotein particle receptor binding 1/187 26/18639 0.0384615384615385 3.83360756890169 0.23075450154548 0.427091382521464 GO:0052742 phosphatidylinositol kinase activity 1/187 26/18639 0.0384615384615385 3.83360756890169 0.23075450154548 0.427091382521464 GO:0097602 cullin family protein binding 1/187 26/18639 0.0384615384615385 3.83360756890169 0.23075450154548 0.427091382521464 GO:0052689 carboxylic ester hydrolase activity 2/187 92/18639 0.0217391304347826 2.16682166937921 0.235721190290235 0.42974148541811 GO:0005385 zinc ion transmembrane transporter activity 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0008395 steroid hydroxylase activity 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0015252 proton channel activity 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0016405 CoA-ligase activity 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0023026 MHC class II protein complex binding 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0035255 ionotropic glutamate receptor binding 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/187 27/18639 0.037037037037037 3.69162210338681 0.238482912237523 0.42974148541811 GO:0140104 molecular carrier activity 4/187 249/18639 0.0160642570281124 1.6011854906256 0.240739814578468 0.432381377499486 GO:0016887 ATP hydrolysis activity 6/187 417/18639 0.0143884892086331 1.43415534951718 0.241974463138016 0.433173956961826 GO:0046875 ephrin receptor binding 1/187 28/18639 0.0357142857142857 3.55977845683728 0.246134088651212 0.433380788412776 GO:0050698 proteoglycan sulfotransferase activity 1/187 28/18639 0.0357142857142857 3.55977845683728 0.246134088651212 0.433380788412776 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/187 28/18639 0.0357142857142857 3.55977845683728 0.246134088651212 0.433380788412776 GO:0097718 disordered domain specific binding 1/187 28/18639 0.0357142857142857 3.55977845683728 0.246134088651212 0.433380788412776 GO:0141052 histone H3 demethylase activity 1/187 28/18639 0.0357142857142857 3.55977845683728 0.246134088651212 0.433380788412776 GO:0004867 serine-type endopeptidase inhibitor activity 2/187 95/18639 0.0210526315789474 2.09839572192513 0.246852427099585 0.433380788412776 GO:0004896 cytokine receptor activity 2/187 96/18639 0.0208333333333333 2.07653743315508 0.250567531367741 0.436987394301294 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/187 29/18639 0.0344827586206897 3.43702747556703 0.253708798522913 0.436987394301294 GO:0016417 S-acyltransferase activity 1/187 29/18639 0.0344827586206897 3.43702747556703 0.253708798522913 0.436987394301294 GO:0043236 laminin binding 1/187 29/18639 0.0344827586206897 3.43702747556703 0.253708798522913 0.436987394301294 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/187 29/18639 0.0344827586206897 3.43702747556703 0.253708798522913 0.436987394301294 GO:0097472 cyclin-dependent protein kinase activity 1/187 29/18639 0.0344827586206897 3.43702747556703 0.253708798522913 0.436987394301294 GO:0003713 transcription coactivator activity 4/187 256/18639 0.015625 1.55740307486631 0.255991340204933 0.439532301106583 GO:0042626 ATPase-coupled transmembrane transporter activity 2/187 98/18639 0.0204081632653061 2.03415911819273 0.258002289080626 0.441546315452167 GO:0001968 fibronectin binding 1/187 30/18639 0.0333333333333333 3.32245989304813 0.26120780199826 0.441546315452167 GO:0016769 transferase activity, transferring nitrogenous groups 1/187 30/18639 0.0333333333333333 3.32245989304813 0.26120780199826 0.441546315452167 GO:0031624 ubiquitin conjugating enzyme binding 1/187 30/18639 0.0333333333333333 3.32245989304813 0.26120780199826 0.441546315452167 GO:0032452 histone demethylase activity 1/187 30/18639 0.0333333333333333 3.32245989304813 0.26120780199826 0.441546315452167 GO:0043021 ribonucleoprotein complex binding 3/187 177/18639 0.0169491525423729 1.68938638629566 0.262297899138901 0.442020533734074 GO:0016878 acid-thiol ligase activity 1/187 31/18639 0.032258064516129 3.21528376746593 0.268631851706806 0.444463609187624 GO:0047499 calcium-independent phospholipase A2 activity 1/187 31/18639 0.032258064516129 3.21528376746593 0.268631851706806 0.444463609187624 GO:0070273 phosphatidylinositol-4-phosphate binding 1/187 31/18639 0.032258064516129 3.21528376746593 0.268631851706806 0.444463609187624 GO:0070325 lipoprotein particle receptor binding 1/187 31/18639 0.032258064516129 3.21528376746593 0.268631851706806 0.444463609187624 GO:0072349 modified amino acid transmembrane transporter activity 1/187 31/18639 0.032258064516129 3.21528376746593 0.268631851706806 0.444463609187624 GO:0140457 protein demethylase activity 1/187 31/18639 0.032258064516129 3.21528376746593 0.268631851706806 0.444463609187624 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/187 181/18639 0.0165745856353591 1.65205188052117 0.273136477641129 0.449808968025134 GO:0015106 bicarbonate transmembrane transporter activity 1/187 32/18639 0.03125 3.11480614973262 0.275981692835934 0.449808968025134 GO:0043425 bHLH transcription factor binding 1/187 32/18639 0.03125 3.11480614973262 0.275981692835934 0.449808968025134 GO:0047498 calcium-dependent phospholipase A2 activity 1/187 32/18639 0.03125 3.11480614973262 0.275981692835934 0.449808968025134 GO:0051059 NF-kappaB binding 1/187 32/18639 0.03125 3.11480614973262 0.275981692835934 0.449808968025134 GO:0019956 chemokine binding 1/187 33/18639 0.0303030303030303 3.02041808458921 0.283258063204058 0.458805679703457 GO:0071889 14-3-3 protein binding 1/187 33/18639 0.0303030303030303 3.02041808458921 0.283258063204058 0.458805679703457 GO:1901981 phosphatidylinositol phosphate binding 3/187 185/18639 0.0162162162162162 1.61633183986125 0.28402256362595 0.458805679703457 GO:0004497 monooxygenase activity 2/187 106/18639 0.0188679245283019 1.88063767531026 0.287745155228484 0.461023501627527 GO:0008013 beta-catenin binding 2/187 106/18639 0.0188679245283019 1.88063767531026 0.287745155228484 0.461023501627527 GO:0008376 acetylgalactosaminyltransferase activity 1/187 34/18639 0.0294117647058824 2.93158225857188 0.290461693333094 0.461023501627527 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/187 34/18639 0.0294117647058824 2.93158225857188 0.290461693333094 0.461023501627527 GO:0019825 oxygen binding 1/187 34/18639 0.0294117647058824 2.93158225857188 0.290461693333094 0.461023501627527 GO:0090482 vitamin transmembrane transporter activity 1/187 34/18639 0.0294117647058824 2.93158225857188 0.290461693333094 0.461023501627527 GO:0005496 steroid binding 2/187 108/18639 0.0185185185185185 1.8458110516934 0.295167304413786 0.465713116150174 GO:0000175 3'-5'-RNA exonuclease activity 1/187 35/18639 0.0285714285714286 2.84782276546982 0.297593306520233 0.465713116150174 GO:0004623 phospholipase A2 activity 1/187 35/18639 0.0285714285714286 2.84782276546982 0.297593306520233 0.465713116150174 GO:0043015 gamma-tubulin binding 1/187 35/18639 0.0285714285714286 2.84782276546982 0.297593306520233 0.465713116150174 GO:0019902 phosphatase binding 3/187 190/18639 0.0157894736842105 1.57379679144385 0.29768109438903 0.465713116150174 GO:0000993 RNA polymerase II complex binding 1/187 36/18639 0.0277777777777778 2.76871657754011 0.304653618909005 0.472559306603172 GO:0016409 palmitoyltransferase activity 1/187 36/18639 0.0277777777777778 2.76871657754011 0.304653618909005 0.472559306603172 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/187 36/18639 0.0277777777777778 2.76871657754011 0.304653618909005 0.472559306603172 GO:1902936 phosphatidylinositol bisphosphate binding 2/187 111/18639 0.018018018018018 1.7959242665125 0.306279417443775 0.473735302901703 GO:0030246 carbohydrate binding 4/187 280/18639 0.0142857142857143 1.42391138273491 0.309539442721759 0.476752703547622 GO:0005200 structural constituent of cytoskeleton 2/187 112/18639 0.0178571428571429 1.77988922841864 0.309976574650926 0.476752703547622 GO:0016758 hexosyltransferase activity 3/187 197/18639 0.0152284263959391 1.51787507804229 0.316863104912688 0.483199590895627 GO:0000146 microfilament motor activity 1/187 38/18639 0.0263157894736842 2.62299465240642 0.318563170518816 0.483199590895627 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/187 38/18639 0.0263157894736842 2.62299465240642 0.318563170518816 0.483199590895627 GO:0042887 amide transmembrane transporter activity 1/187 38/18639 0.0263157894736842 2.62299465240642 0.318563170518816 0.483199590895627 GO:0035091 phosphatidylinositol binding 4/187 284/18639 0.0140845070422535 1.40385629283724 0.318593136854259 0.483199590895627 GO:0016829 lyase activity 3/187 200/18639 0.015 1.49510695187166 0.325094189622034 0.49081750983739 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/187 39/18639 0.0256410256410256 2.55573837926779 0.325413806888526 0.49081750983739 GO:1990782 protein tyrosine kinase binding 2/187 117/18639 0.0170940170940171 1.70382558617853 0.328397476332772 0.493953228864169 GO:0004532 RNA exonuclease activity 1/187 40/18639 0.025 2.4918449197861 0.33219593689454 0.494220658159179 GO:0032451 demethylase activity 1/187 40/18639 0.025 2.4918449197861 0.33219593689454 0.494220658159179 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/187 40/18639 0.025 2.4918449197861 0.33219593689454 0.494220658159179 GO:0071855 neuropeptide receptor binding 1/187 40/18639 0.025 2.4918449197861 0.33219593689454 0.494220658159179 GO:0001727 lipid kinase activity 1/187 41/18639 0.024390243902439 2.43106821442546 0.33891024195399 0.500121600288861 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/187 41/18639 0.024390243902439 2.43106821442546 0.33891024195399 0.500121600288861 GO:0042287 MHC protein binding 1/187 41/18639 0.024390243902439 2.43106821442546 0.33891024195399 0.500121600288861 GO:0004540 RNA nuclease activity 2/187 121/18639 0.0165289256198347 1.6475007734123 0.343039821462028 0.501793453780168 GO:0004520 DNA endonuclease activity 1/187 42/18639 0.0238095238095238 2.37318563789152 0.345557396742387 0.501793453780168 GO:0019894 kinesin binding 1/187 42/18639 0.0238095238095238 2.37318563789152 0.345557396742387 0.501793453780168 GO:0035198 miRNA binding 1/187 42/18639 0.0238095238095238 2.37318563789152 0.345557396742387 0.501793453780168 GO:0043175 RNA polymerase core enzyme binding 1/187 42/18639 0.0238095238095238 2.37318563789152 0.345557396742387 0.501793453780168 GO:0048487 beta-tubulin binding 1/187 42/18639 0.0238095238095238 2.37318563789152 0.345557396742387 0.501793453780168 GO:0001664 G protein-coupled receptor binding 4/187 297/18639 0.0134680134680135 1.3424080375952 0.348139950130786 0.504202686396311 GO:0004518 nuclease activity 3/187 209/18639 0.0143540669856459 1.43072435585805 0.349775866532525 0.504638807915838 GO:0008200 ion channel inhibitor activity 1/187 43/18639 0.0232558139534884 2.31799527421962 0.352138069259953 0.504638807915838 GO:0008375 acetylglucosaminyltransferase activity 1/187 43/18639 0.0232558139534884 2.31799527421962 0.352138069259953 0.504638807915838 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/187 43/18639 0.0232558139534884 2.31799527421962 0.352138069259953 0.504638807915838 GO:0001223 transcription coactivator binding 1/187 44/18639 0.0227272727272727 2.26531356344191 0.358652920897315 0.508635051454374 GO:0016248 channel inhibitor activity 1/187 44/18639 0.0227272727272727 2.26531356344191 0.358652920897315 0.508635051454374 GO:0016790 thiolester hydrolase activity 1/187 44/18639 0.0227272727272727 2.26531356344191 0.358652920897315 0.508635051454374 GO:0019205 nucleobase-containing compound kinase activity 1/187 44/18639 0.0227272727272727 2.26531356344191 0.358652920897315 0.508635051454374 GO:0004519 endonuclease activity 2/187 127/18639 0.015748031496063 1.56966609120384 0.364808221459963 0.511143649100774 GO:0042605 peptide antigen binding 1/187 45/18639 0.0222222222222222 2.21497326203209 0.365102606500553 0.511143649100774 GO:0046915 transition metal ion transmembrane transporter activity 1/187 45/18639 0.0222222222222222 2.21497326203209 0.365102606500553 0.511143649100774 GO:0140303 intramembrane lipid transporter activity 1/187 45/18639 0.0222222222222222 2.21497326203209 0.365102606500553 0.511143649100774 GO:0141110 transporter inhibitor activity 1/187 45/18639 0.0222222222222222 2.21497326203209 0.365102606500553 0.511143649100774 GO:0030276 clathrin binding 1/187 46/18639 0.0217391304347826 2.16682166937921 0.371487774435607 0.518752748956116 GO:0061749 forked DNA-dependent helicase activity 1/187 47/18639 0.0212765957446809 2.12071908066902 0.377809066652061 0.519715506763718 GO:0140938 histone H3 methyltransferase activity 1/187 47/18639 0.0212765957446809 2.12071908066902 0.377809066652061 0.519715506763718 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/187 47/18639 0.0212765957446809 2.12071908066902 0.377809066652061 0.519715506763718 GO:0009378 four-way junction helicase activity 1/187 48/18639 0.0208333333333333 2.07653743315508 0.384067118746299 0.519715506763718 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/187 48/18639 0.0208333333333333 2.07653743315508 0.384067118746299 0.519715506763718 GO:0032266 phosphatidylinositol-3-phosphate binding 1/187 48/18639 0.0208333333333333 2.07653743315508 0.384067118746299 0.519715506763718 GO:0036121 double-stranded DNA helicase activity 1/187 48/18639 0.0208333333333333 2.07653743315508 0.384067118746299 0.519715506763718 GO:0043138 3'-5' DNA helicase activity 1/187 48/18639 0.0208333333333333 2.07653743315508 0.384067118746299 0.519715506763718 GO:0051020 GTPase binding 4/187 315/18639 0.0126984126984127 1.26569900687548 0.389096520792378 0.519715506763718 GO:0005004 GPI-linked ephrin receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0005008 hepatocyte growth factor receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0005009 insulin receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0005011 macrophage colony-stimulating factor receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0005020 stem cell factor receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0008288 boss receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0036332 placental growth factor receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0038062 protein tyrosine kinase collagen receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0060175 brain-derived neurotrophic factor receptor activity 1/187 49/18639 0.0204081632653061 2.03415911819273 0.390262560024038 0.519715506763718 GO:0005007 fibroblast growth factor receptor activity 1/187 50/18639 0.02 1.99347593582888 0.396396013562257 0.523484387258154 GO:0005017 platelet-derived growth factor receptor activity 1/187 50/18639 0.02 1.99347593582888 0.396396013562257 0.523484387258154 GO:0005019 platelet-derived growth factor beta-receptor activity 1/187 50/18639 0.02 1.99347593582888 0.396396013562257 0.523484387258154 GO:0019838 growth factor binding 2/187 136/18639 0.0147058823529412 1.46579112928594 0.396927722206732 0.523484387258154 GO:0003743 translation initiation factor activity 1/187 51/18639 0.0196078431372549 1.95438817238125 0.402468096270518 0.52571191522417 GO:0005010 insulin-like growth factor receptor activity 1/187 51/18639 0.0196078431372549 1.95438817238125 0.402468096270518 0.52571191522417 GO:0005021 vascular endothelial growth factor receptor activity 1/187 51/18639 0.0196078431372549 1.95438817238125 0.402468096270518 0.52571191522417 GO:0005030 neurotrophin receptor activity 1/187 51/18639 0.0196078431372549 1.95438817238125 0.402468096270518 0.52571191522417 GO:0000287 magnesium ion binding 3/187 230/18639 0.0130434782608696 1.30009300162753 0.406856527080664 0.52992763502029 GO:0004864 protein phosphatase inhibitor activity 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0005003 ephrin receptor activity 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0005005 transmembrane-ephrin receptor activity 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0005544 calcium-dependent phospholipid binding 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0008146 sulfotransferase activity 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0017046 peptide hormone binding 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0038064 collagen receptor activity 1/187 53/18639 0.0188679245283019 1.88063767531026 0.414430586362021 0.52992763502029 GO:0019955 cytokine binding 2/187 144/18639 0.0138888888888889 1.38435828877005 0.424843638176073 0.541117546761492 GO:0008374 O-acyltransferase activity 1/187 55/18639 0.0181818181818182 1.81225085075352 0.426154844519124 0.541117546761492 GO:0140313 molecular sequestering activity 1/187 55/18639 0.0181818181818182 1.81225085075352 0.426154844519124 0.541117546761492 GO:0019212 phosphatase inhibitor activity 1/187 56/18639 0.0178571428571429 1.77988922841864 0.431929115078472 0.543424194533311 GO:0030170 pyridoxal phosphate binding 1/187 56/18639 0.0178571428571429 1.77988922841864 0.431929115078472 0.543424194533311 GO:0170055 lipid transmembrane transporter activity 1/187 56/18639 0.0178571428571429 1.77988922841864 0.431929115078472 0.543424194533311 GO:0045296 cadherin binding 4/187 334/18639 0.0119760479041916 1.19369816516699 0.431952564885452 0.543424194533311 GO:0140097 catalytic activity, acting on DNA 4/187 336/18639 0.0119047619047619 1.18659281894576 0.436422974320929 0.547786078113166 GO:0070279 vitamin B6 binding 1/187 57/18639 0.0175438596491228 1.74866310160428 0.437645590108356 0.548060761924684 GO:0005539 glycosaminoglycan binding 3/187 242/18639 0.012396694214876 1.23562558005922 0.438841930850498 0.548301359826938 GO:0008408 3'-5' exonuclease activity 1/187 58/18639 0.0172413793103448 1.71851373778351 0.443304845013626 0.551354089698041 GO:0017116 single-stranded DNA helicase activity 1/187 58/18639 0.0172413793103448 1.71851373778351 0.443304845013626 0.551354089698041 GO:0001786 phosphatidylserine binding 1/187 59/18639 0.0169491525423729 1.68938638629566 0.448907449501138 0.552034836548696 GO:0015459 potassium channel regulator activity 1/187 59/18639 0.0169491525423729 1.68938638629566 0.448907449501138 0.552034836548696 GO:0031593 polyubiquitin modification-dependent protein binding 1/187 59/18639 0.0169491525423729 1.68938638629566 0.448907449501138 0.552034836548696 GO:0036002 pre-mRNA binding 1/187 59/18639 0.0169491525423729 1.68938638629566 0.448907449501138 0.552034836548696 GO:0070063 RNA polymerase binding 1/187 59/18639 0.0169491525423729 1.68938638629566 0.448907449501138 0.552034836548696 GO:0042393 histone binding 3/187 247/18639 0.0121457489878543 1.21061291649527 0.45198131990889 0.552592780177176 GO:0001098 basal transcription machinery binding 1/187 60/18639 0.0166666666666667 1.66122994652406 0.454453967635868 0.552592780177176 GO:0001099 basal RNA polymerase II transcription machinery binding 1/187 60/18639 0.0166666666666667 1.66122994652406 0.454453967635868 0.552592780177176 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/187 60/18639 0.0166666666666667 1.66122994652406 0.454453967635868 0.552592780177176 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/187 60/18639 0.0166666666666667 1.66122994652406 0.454453967635868 0.552592780177176 GO:0003774 cytoskeletal motor activity 2/187 153/18639 0.0130718954248366 1.30292544825417 0.455433610036134 0.552592780177176 GO:0015026 coreceptor activity 1/187 61/18639 0.0163934426229508 1.63399666871219 0.45994495789649 0.556829150801515 GO:0004386 helicase activity 2/187 155/18639 0.0129032258064516 1.28611350698637 0.462105368503936 0.558206927440595 GO:1901682 sulfur compound transmembrane transporter activity 1/187 63/18639 0.0158730158730159 1.58212375859435 0.4707625611082 0.567409179613857 GO:0004536 DNA nuclease activity 1/187 64/18639 0.015625 1.55740307486631 0.476090263577664 0.572566704655076 GO:0120013 lipid transfer activity 1/187 65/18639 0.0153846153846154 1.53344302756067 0.481364617317151 0.575667445825526 GO:0160215 deacylase activity 1/187 65/18639 0.0153846153846154 1.53344302756067 0.481364617317151 0.575667445825526 GO:0004866 endopeptidase inhibitor activity 2/187 161/18639 0.0124223602484472 1.23818381107384 0.481831543484002 0.575667445825526 GO:0003730 mRNA 3'-UTR binding 3/187 262/18639 0.0114503816793893 1.14130301669592 0.490607834836682 0.583692277693601 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/187 67/18639 0.0149253731343284 1.48766860882752 0.491755398789481 0.583692277693601 GO:0042054 histone methyltransferase activity 1/187 67/18639 0.0149253731343284 1.48766860882752 0.491755398789481 0.583692277693601 GO:0003777 microtubule motor activity 1/187 68/18639 0.0147058823529412 1.46579112928594 0.496872873505524 0.585945116488156 GO:0030145 manganese ion binding 1/187 68/18639 0.0147058823529412 1.46579112928594 0.496872873505524 0.585945116488156 GO:0140223 general transcription initiation factor activity 1/187 68/18639 0.0147058823529412 1.46579112928594 0.496872873505524 0.585945116488156 GO:0016874 ligase activity 2/187 167/18639 0.0119760479041916 1.19369816516699 0.501109584293928 0.589373645342861 GO:0016279 protein-lysine N-methyltransferase activity 1/187 69/18639 0.0144927536231884 1.44454777958614 0.501939093561228 0.589373645342861 GO:0016278 lysine N-methyltransferase activity 1/187 70/18639 0.0142857142857143 1.42391138273491 0.506954569571139 0.591611787540929 GO:0016782 transferase activity, transferring sulphur-containing groups 1/187 70/18639 0.0142857142857143 1.42391138273491 0.506954569571139 0.591611787540929 GO:0030414 peptidase inhibitor activity 2/187 169/18639 0.0118343195266272 1.17957155966206 0.507433221479274 0.591611787540929 GO:0008514 organic anion transmembrane transporter activity 3/187 269/18639 0.0111524163568773 1.11160368168896 0.508179355964644 0.591611787540929 GO:0004521 RNA endonuclease activity 1/187 73/18639 0.0136986301369863 1.36539447659512 0.52170156387521 0.606061816757159 GO:0003823 antigen binding 2/187 174/18639 0.0114942528735632 1.14567582518901 0.523013656042489 0.606296085348618 GO:0003678 DNA helicase activity 1/187 74/18639 0.0135135135135135 1.34694319988438 0.526519069399035 0.607778883492333 GO:0031491 nucleosome binding 1/187 74/18639 0.0135135135135135 1.34694319988438 0.526519069399035 0.607778883492333 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/187 484/18639 0.0103305785123967 1.02968798338268 0.536654460665114 0.618171593930701 GO:0003724 RNA helicase activity 1/187 77/18639 0.012987012987013 1.29446489339537 0.540683909913232 0.620806968652306 GO:0016853 isomerase activity 2/187 180/18639 0.0111111111111111 1.10748663101604 0.541271768971415 0.620806968652306 GO:0031267 small GTPase binding 3/187 283/18639 0.0106007067137809 1.05661268683509 0.542353340745696 0.620806968652306 GO:0001216 DNA-binding transcription activator activity 5/187 491/18639 0.010183299389002 1.01500811396582 0.549461592779541 0.626808179539525 GO:0008186 ATP-dependent activity, acting on RNA 1/187 79/18639 0.0126582278481013 1.26169363027144 0.549892157508118 0.626808179539525 GO:0061135 endopeptidase regulator activity 2/187 184/18639 0.0108695652173913 1.08341083468961 0.553174045983219 0.629235477305911 GO:0001618 virus receptor activity 1/187 81/18639 0.0123456790123457 1.23054070112894 0.558916768066512 0.634446061048474 GO:0140272 exogenous protein binding 1/187 82/18639 0.0121951219512195 1.21553410721273 0.563361350692418 0.637855382589642 GO:0046943 carboxylic acid transmembrane transporter activity 2/187 188/18639 0.0106382978723404 1.06035954033451 0.564858165341159 0.637855382589642 GO:0005342 organic acid transmembrane transporter activity 2/187 189/18639 0.0105820105820106 1.05474917239623 0.567744929577396 0.637855382589642 GO:0008135 translation factor activity, RNA binding 1/187 83/18639 0.0120481927710843 1.2008891179692 0.567761384502868 0.637855382589642 GO:0030165 PDZ domain binding 1/187 83/18639 0.0120481927710843 1.2008891179692 0.567761384502868 0.637855382589642 GO:0004527 exonuclease activity 1/187 84/18639 0.0119047619047619 1.18659281894576 0.572117313641582 0.640114863213737 GO:0180051 translation factor activity 1/187 84/18639 0.0119047619047619 1.18659281894576 0.572117313641582 0.640114863213737 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/187 86/18639 0.0116279069767442 1.15899763710981 0.580698612500439 0.648387407822577 GO:0017171 serine hydrolase activity 2/187 198/18639 0.0101010101010101 1.0068060281964 0.593105703225688 0.658363502256066 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/187 89/18639 0.0112359550561798 1.11993030102746 0.593250628406565 0.658363502256066 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/187 89/18639 0.0112359550561798 1.11993030102746 0.593250628406565 0.658363502256066 GO:0140793 histone H2AXY142 phosphatase activity 1/187 90/18639 0.0111111111111111 1.10748663101604 0.597351012907264 0.661569275958147 GO:0072341 modified amino acid binding 1/187 91/18639 0.010989010989011 1.09531644825762 0.601410280823936 0.664716626173824 GO:0042562 hormone binding 1/187 94/18639 0.0106382978723404 1.06035954033451 0.613345465785284 0.676538634987404 GO:0008276 protein methyltransferase activity 1/187 95/18639 0.0105263157894737 1.04919786096257 0.617244327898961 0.679466538372647 GO:0016407 acetyltransferase activity 1/187 96/18639 0.0104166666666667 1.03826871657754 0.621104083651921 0.682339697533097 GO:0004725 protein tyrosine phosphatase activity 1/187 98/18639 0.0102040816326531 1.01707955909637 0.628707832831027 0.687924803057596 GO:0008170 N-methyltransferase activity 1/187 98/18639 0.0102040816326531 1.01707955909637 0.628707832831027 0.687924803057596 GO:0043130 ubiquitin binding 1/187 100/18639 0.01 0.996737967914439 0.636159788345298 0.694686488873065 GO:0000149 SNARE binding 1/187 106/18639 0.00943396226415094 0.940318837655131 0.657634739264246 0.716703727820914 GO:0061134 peptidase regulator activity 2/187 226/18639 0.00884955752212389 0.88206899815437 0.664866634856113 0.723141798070593 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/187 229/18639 0.00873362445414847 0.870513509095579 0.671922242190115 0.729362911005572 GO:0043022 ribosome binding 1/187 112/18639 0.00892857142857143 0.88994461420932 0.677848551754426 0.734335931067295 GO:0015294 solute:monoatomic cation symporter activity 1/187 116/18639 0.00862068965517241 0.859256868891757 0.690660361907545 0.745463841825105 GO:0061630 ubiquitin protein ligase activity 3/187 353/18639 0.0084985835694051 0.847086091711988 0.690851106160262 0.745463841825105 GO:0032182 ubiquitin-like protein binding 1/187 120/18639 0.00833333333333333 0.830614973262032 0.702965269016707 0.75703952047953 GO:0003697 single-stranded DNA binding 1/187 121/18639 0.00826446280991736 0.823750386706148 0.705964647746329 0.758773026908456 GO:0042578 phosphoric ester hydrolase activity 3/187 363/18639 0.00826446280991736 0.823750386706148 0.708834357150236 0.758976292804619 GO:0008528 G protein-coupled peptide receptor activity 1/187 122/18639 0.00819672131147541 0.816998334356097 0.708933899872446 0.758976292804619 GO:0046982 protein heterodimerization activity 3/187 369/18639 0.00813008130081301 0.810356071475153 0.719236206416103 0.76849896028022 GO:0061659 ubiquitin-like protein ligase activity 3/187 372/18639 0.00806451612903226 0.803820941866483 0.724328807860463 0.772428767757447 GO:0001653 peptide receptor activity 1/187 128/18639 0.0078125 0.778701537433155 0.726133401639507 0.772843737417487 GO:0035591 signaling adaptor activity 1/187 129/18639 0.00775193798449612 0.772665091406541 0.728900029800785 0.774279019982935 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/187 130/18639 0.00769230769230769 0.766721513780337 0.731638857160442 0.775679254387575 GO:0044325 transmembrane transporter binding 1/187 136/18639 0.00735294117647059 0.73289556464297 0.747503373509353 0.789193574581123 GO:0140789 histone phosphatase activity 1/187 136/18639 0.00735294117647059 0.73289556464297 0.747503373509353 0.789193574581123 GO:0140098 catalytic activity, acting on RNA 3/187 387/18639 0.00775193798449612 0.772665091406541 0.748722109217989 0.789193574581123 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/187 268/18639 0.00746268656716418 0.74383430441376 0.753073514551347 0.7922507494124 GO:1901681 sulfur compound binding 2/187 275/18639 0.00727272727272727 0.72490034030141 0.765670454491836 0.803953977216428 GO:0019903 protein phosphatase binding 1/187 144/18639 0.00694444444444444 0.692179144385027 0.767214054233608 0.804028548198752 GO:0001217 DNA-binding transcription repressor activity 2/187 278/18639 0.00719424460431655 0.717077674758589 0.770897103069345 0.805843494193272 GO:0015293 symporter activity 1/187 146/18639 0.00684931506849315 0.682697238297561 0.771897705976339 0.805843494193272 GO:0019842 vitamin binding 1/187 150/18639 0.00666666666666667 0.664491978609626 0.780985652131127 0.813775126075563 GO:0099106 ion channel regulator activity 1/187 160/18639 0.00625 0.622961229946524 0.802160480423994 0.834246899640954 GO:0015103 inorganic anion transmembrane transporter activity 1/187 165/18639 0.00606060606060606 0.604083616917842 0.81197124002659 0.842844671206308 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/187 167/18639 0.00598802395209581 0.596849082583496 0.81575865613246 0.845169309769114 GO:0016247 channel regulator activity 1/187 168/18639 0.00595238095238095 0.59329640947288 0.817623810490582 0.845497349484579 GO:0141108 transporter regulator activity 1/187 170/18639 0.00588235294117647 0.586316451714376 0.821297961916486 0.847691280163329 GO:0008201 heparin binding 1/187 172/18639 0.00581395348837209 0.579498818554906 0.824898481756888 0.848988635560987 GO:0140030 modification-dependent protein binding 1/187 173/18639 0.00578034682080925 0.576149114401409 0.826671589674334 0.848988635560987 GO:0003735 structural constituent of ribosome 1/187 175/18639 0.00571428571428571 0.569564553093965 0.830164405206724 0.848988635560987 GO:0004721 phosphoprotein phosphatase activity 1/187 175/18639 0.00571428571428571 0.569564553093965 0.830164405206724 0.848988635560987 GO:0004842 ubiquitin-protein transferase activity 3/187 449/18639 0.0066815144766147 0.665971916201184 0.831763695559255 0.848988635560987 GO:0004252 serine-type endopeptidase activity 1/187 176/18639 0.00568181818181818 0.566328390860476 0.831884468910491 0.848988635560987 GO:0008236 serine-type peptidase activity 1/187 194/18639 0.00515463917525773 0.513782457687855 0.860044224919598 0.876089826130785 GO:0019787 ubiquitin-like protein transferase activity 3/187 479/18639 0.00626304801670146 0.624261775311757 0.862748279673024 0.877207748047432 GO:0008168 methyltransferase activity 1/187 204/18639 0.00490196078431373 0.488597043095313 0.873606308017081 0.886596736389082 GO:0016755 aminoacyltransferase activity 3/187 496/18639 0.00604838709677419 0.602865706399862 0.877999669185875 0.889402262292185 GO:0016741 transferase activity, transferring one-carbon groups 1/187 215/18639 0.00465116279069767 0.463599054843925 0.887018964600989 0.896874730874333 GO:0016791 phosphatase activity 1/187 273/18639 0.00366300366300366 0.365105482752542 0.9375353063442 0.946200142816882 GO:0015291 secondary active transmembrane transporter activity 1/187 287/18639 0.00348432055749129 0.347295459203637 0.945876209588057 0.952856845821179 GO:0003924 GTPase activity 1/187 331/18639 0.00302114803625378 0.301129295442429 0.965529669477266 0.970864087540676 GO:0005261 monoatomic cation channel activity 1/187 341/18639 0.00293255131964809 0.292298524315085 0.968893797550509 0.972455907100327 GO:0005216 monoatomic ion channel activity 1/187 448/18639 0.00223214285714286 0.22248615355233 0.989669908377454 0.989881205259811 GO:0046873 metal ion transmembrane transporter activity 1/187 450/18639 0.00222222222222222 0.221497326203209 0.989881205259811 0.989881205259811