category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	20/148	275/9376	4.60737100737101	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/EGR1/HSPA5/MT-ND4L/MT-ND6/HSPA8/TNF/C1QA/TUBB4B/IL6/CAV1	7.68909635440908
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	12/148	94/9376	8.08740655549166	FOS/FOSB/JUN/S100A8/CCL2/JUND/HSP90B1/NFKBIA/TNF/HSP90AB1/IL6/FOSL1	8.74567216631261
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	14/148	142/9376	6.2459078797107	FOS/HMOX1/DUSP1/ACTB/JUN/CCL2/ACTG1/CTSL/KLF2/HSP90B1/TNF/MGST1/HSP90AB1/CAV1	7.97687157278817
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	17/148	227/9376	4.74437433027741	FOS/MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/HMOX1/MT-ND5/JUN/MT-ND4L/MT-ND6/NFKBIA/MGST1	7.23216085564832
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	16/148	205/9376	4.94449571522742	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/MT-ND4L/MT-ND6/CAMK2D/PDK4/COL1A2/COL1A1	7.23140650237125
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	17/148	268/9376	4.01855586930214	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/DUSP1/MT-ND5/UBC/HSPA5/MT-ND4L/MT-ND6/CAMK2D/TUBB4B	6.34918245494574
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	12/148	138/9376	5.50881316098707	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/MT-ND4L/MT-ND6	6.75733587747504
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	16/148	248/9376	4.0871839581517	FOS/ACTB/S100A10/AHNAK/JUN/ACTG1/RHOB/HSP90B1/NFKBIA/FLNA/TNF/HSP90AB1/TUBB4B/ANXA2/IL6/DYNC1I1	6.23969320276206
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	15/148	235/9376	4.04370327774583	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/ACTB/ACTG1/MT-ND4L/PPARG/MT-ND6	5.98414477105494
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	12/148	155/9376	4.90462074978204	ACTB/HLA-C/MARCO/OLR1/CALR/CLEC7A/ACTG1/CTSL/MSR1/ITGA5/TUBB4B/DYNC1I1	6.20752387958934
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	14/148	216/9376	4.10610610610611	FOS/HSPA5/CCL3/JUN/OLR1/CCL2/PPARG/HSP90B1/HSPA8/NFKBIA/CAMK2D/TNF/HSP90AB1/IL6	5.84868361860871
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	11/148	137/9376	5.08660485302821	FOS/ACTB/MCL1/JUN/ACTG1/CTSL/NFKBIA/GADD45G/TNF/CTSZ/LMNA	6.10201329308666
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	9/148	103/9376	5.53555497244818	FOS/CCL3/JUN/CALR/CCL2/NFKBIA/TNF/C1QA/IL6	5.86140351652627
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	11/148	157/9376	4.43862971251506	FOS/MT-CO1/MT-CO3/MT-CO2/MT-CYB/JUN/NR1H3/PPARG/TNF/SOCS3/IL6	5.50244909194662
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	10/148	138/9376	4.5906776341559	FOS/ACTB/JUN/CCL2/ACTG1/FN1/NFKBIA/ITGA5/TNF/IL6	5.38133072615877
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	17/148	368/9376	2.92655699177438	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/ACTB/HSPA5/ACTG1/MT-ND4L/MT-ND6/TNF/TUBB4B	4.77479009717942
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	13/148	233/9376	3.53462475350887	FMNL2/ACTB/VIM/ACTG1/FN1/TPM4/PLEC/SNTB1/ITGA5/VCAN/LMNA/COL1A2/COL1A1	4.96146549705494
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	12/148	204/9376	3.72655007949126	ACTB/ACTG1/CTSL/FN1/FLNA/CAMK2D/ITGA5/TNF/CDKN1A/COL1A2/CAV1/COL1A1	4.98608000293636
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	8/148	99/9376	5.11930111930112	ACTB/ACTG1/TPM4/SNTB1/ITGA5/TNF/IL6/LMNA	5.21795178546184
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	8/148	101/9376	5.01792881990902	EGR1/JUN/CCL2/FN1/TNF/IL6/COL1A2/COL1A1	5.14124937126014
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	12/148	224/9376	3.39382239382239	FOS/ZFP36/EGR1/HLA-C/JUN/CALR/EGR2/NFKBIA/TNF/CDKN1A/IL6/FOSL1	4.59219828268323
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	7/148	82/9376	5.40804218852999	HLA-C/HSPA5/CALR/CTSL/HSPA8/TNF/HSP90AB1	5.07708036042969
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	14/148	308/9376	2.87960687960688	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/MT-ND4L/PPARG/MT-ND6/TUBB4B	4.24765593770936
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	11/148	203/9376	3.43283184662495	ACTB/JUN/ACTG1/FN1/FLNB/EMP1/FLNA/ITGA5/COL1A2/CAV1/COL1A1	4.43779378304157
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	12/148	238/9376	3.19418578242108	FOS/ISG15/C5AR1/JUN/CCL2/NFKBIA/MX1/TNF/RPL35/C1QA/IL6/RPL8	4.34209180272292
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	16/148	388/9376	2.61242685984954	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/APOE/MT-ND4L/MT-ND6/TNF/TUBB4B/IL6	4.10796805702888
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	9/148	142/9376	4.01522649409973	FOS/FOSB/JUN/JUND/PPARG/NFKBIA/TNF/SOCS3/FOSL1	4.58492124867971
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	18/148	480/9376	2.37567567567568	MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/UBC/HSPA5/MT-ND4L/MT-ND6/CAMK2D/TNF/TUBB4B/IL6	3.9183388736594
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	7/148	95/9376	4.66799431009957	FOS/CCL3/JUN/CCL2/CTSL/TNF/IL6	4.55046493984272
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	4/148	30/9376	8.44684684684685	ABCC3/DHFR/TNF/IL6	5.17348106791074
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	7/148	105/9376	4.22342342342342	ACTB/ACTG1/TPM4/SNTB1/ITGA5/TNF/LMNA	4.20640823907793
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/148	78/9376	4.87318087318087	FOS/JUN/ITGA5/TNF/C1QA/IL6	4.34993744862122
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	10/148	205/9376	3.09030982201714	ISG15/HLA-C/JUN/CALR/VIM/NFKBIA/GADD45G/TNF/CDKN1A/IL6	3.83214512834975
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	9/148	173/9376	3.29573504139978	ACTB/CCL2/ACTG1/NFKBIA/MX1/TNF/SOCS3/IL6/PABPN1	3.85960452357321
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	7/148	109/9376	4.06843540788495	FOS/CCL3/JUN/CCL4/NFKBIA/TNF/IL6	4.08059371225637
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	14/148	362/9376	2.45005226220696	CSH1/MCL1/CSH2/FN1/CSHL1/HSP90B1/ITGA5/NR4A1/CDKN1A/HSP90AB1/IL6/SGK1/COL1A2/COL1A1	3.56321367596365
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	5/148	56/9376	5.65637065637066	HSPA8/NFKBIA/EEF1A1/TNF/IL6	4.42584605816942
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	7/148	115/9376	3.85616921269095	FOS/EGR1/NR4A2/JUND/MAFB/CDKN1A/SGK1	3.90271299531355
Organismal Systems	Digestive system	hsa04978	Mineral absorption	5/148	61/9376	5.19273371732388	HMOX1/FTH1/FTL/SLC26A3/MT2A	4.16038452091615
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	7/148	119/9376	3.72655007949126	FOS/JUN/CCL2/NFKBIA/TNF/SOCS3/IL6	3.79065736610932
NA	NA	hsa04518	Integrin signaling	8/148	154/9376	3.29097929097929	ACTB/ACTG1/FN1/FLNB/FLNA/ITGA5/COL1A2/COL1A1	3.63020932395415
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	8/148	154/9376	3.29097929097929	FOS/ACTB/JUN/ACTG1/CAMK2D/RGS2/CDKN1A/MYL6	3.63020932395415
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	8/148	157/9376	3.22809433637459	CALR/STAB1/NR1H3/PPARG/CAMK2D/C1QA/SGK1/SIGLEC10	3.56536663815094
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	4/148	42/9376	6.03346203346203	HMOX1/FTH1/FTL/SLC7A11	4.14018976162967
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/148	70/9376	4.52509652509652	ACTB/HLA-C/ACTG1/SNTB1/CAV1	3.74887717959295
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	6/148	105/9376	3.62007722007722	JUN/CLEC7A/EGR2/NFKBIA/TNF/IL6	3.41907126611629
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	7/148	139/9376	3.19035582344935	FOS/JUN/HSP90B1/HSPA8/FKBP5/GABBR1/HSP90AB1	3.29472599939257
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	5/148	76/9376	4.1678520625889	UBC/OLR1/NR1H3/PPARG/FABP5	3.511501973663
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	8/148	180/9376	2.81561561561562	HLA-C/CALR/CCL2/NFKBIA/ITGA5/TNF/SOCS3/IL6	3.11475135593254
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	5/148	78/9376	4.06098406098406	ACTB/ACTG1/FN1/ITGA5/CAV1	3.43776591707997
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/148	78/9376	4.06098406098406	FOS/JUN/NFKBIA/EEF1A1/TNF	3.43776591707997
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	7/148	149/9376	2.97623798294939	MT-ND3/MT-ND2/MT-ND1/MT-ND4/MT-ND5/MT-ND4L/MT-ND6	3.07939087825593
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	8/148	187/9376	2.71021823963	TXNIP/JUN/CCL2/NFKBIA/TNF/HSP90AB1/IL6/GABARAPL1	2.99158202018432
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	9/148	227/9376	2.51172758661745	HLA-C/CCL3/CALR/CCL2/CCL4/NFKBIA/TNF/CDKN1A/IL6	2.91986220179232
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/148	86/9376	3.68321810182275	ACTB/ACTG1/SNTB1/ITGA5/LMNA	3.16562922561398
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/148	87/9376	3.64088226157192	MT-CO1/MT-CO3/MT-CO2/MT-CYB/TPM4	3.13391264934388
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	8/148	196/9376	2.5857694429123	FOS/ZFP36/UBC/HLA-C/JUN/NFKBIA/CDKN1A/IL6	2.84124996236627
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	8/148	200/9376	2.53405405405405	FOS/ACTB/JUN/ACTG1/NFKBIA/TNF/TUBB4B/IL6	2.77710091203432
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	7/148	163/9376	2.72061018073288	FOS/JUN/EGR2/NFKBIA/TNF/CDKN1A/IL6	2.80632818363313
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	7/148	168/9376	2.63963963963964	CSH1/MCL1/CSH2/CSHL1/CDKN1A/SOCS3/IL6	2.71570816307475
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	9/148	250/9376	2.28064864864865	VAMP8/PSAP/CTSL/SLC11A1/LAPTM5/SLC36A1/GAA/CTSZ/CD68	2.5990968964587
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	7/148	170/9376	2.60858505564388	HMOX1/ACTB/ACTG1/GADD45G/CDKN1A/MGST1/TXNRD1	2.68037592215963
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	6/148	133/9376	2.85795570006096	KLF2/GADD45G/CDKN1A/IL6/SGK1/GABARAPL1	2.73286011083625
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	7/148	174/9376	2.54861758310034	HSPA5/CALR/HSP90B1/HSPA8/DNAJA1/RPN1/HSP90AB1	2.61120157250057
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	3/148	37/9376	5.13659605551497	PPARG/GADD45G/CDKN1A	3.19268807993734
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	10/148	300/9376	2.11171171171171	FOS/DUSP1/DUSP6/JUN/JUND/HSPA8/FLNA/GADD45G/TNF/NR4A1	2.47838212215399
Human Diseases	Infectious disease: viral	hsa05162	Measles	6/148	136/9376	2.79491255961844	FOS/JUN/HSPA8/NFKBIA/MX1/IL6	2.67017341743703
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/148	100/9376	3.16756756756757	CCL3/CCL2/CCL4/TNF/IL6	2.75965617774708
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	5/148	103/9376	3.07530831802676	FN1/TNF/IL6/COL1A2/COL1A1	2.68196936142356
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	4/148	69/9376	3.67254210732472	FOS/FOSB/JUN/CAMK2D	2.82167472399606
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	8/148	226/9376	2.24252571155226	FOS/JUN/CGA/NFKBIA/GABBR1/CAMK2D/CRH/SUCNR1	2.39448300996248
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/148	109/9376	2.90602529134639	FOS/JUN/NFKBIA/HSP90AB1/IL6	2.5347494033224
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	5/148	109/9376	2.90602529134639	NR1H3/NFKBIA/TNF/SOCS3/IL6	2.5347494033224
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	4/148	75/9376	3.37873873873874	HSPA5/CGA/HSP90B1/TG	2.61923977855073
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/148	45/9376	4.22342342342342	HLA-C/TNF/IL6	2.7448727933985
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	3/148	46/9376	4.13160987074031	HMOX1/FTH1/FTL	2.69630148075774
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	6/148	156/9376	2.43659043659044	NR1H3/NFKBIA/MX1/TNF/CDKN1A/SOCS3	2.29135570122396
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	6/148	157/9376	2.42107075228094	HLA-C/ZFP36L1/ZFP36L2/GADD45G/CDKN1A/IL6	2.27397833562049
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	5/148	122/9376	2.59636685866194	FOS/CSH1/CSH2/CSHL1/SOCS3	2.24755627103517
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/148	50/9376	3.80108108108108	CCL2/TNF/IL6	2.51492871630913
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	4/148	87/9376	2.91270580925753	FOS/JUN/GADD45G/CDKN1A	2.26979181061172
Organismal Systems	Immune system	hsa04611	Platelet activation	5/148	126/9376	2.51394251394251	ACTB/ACTG1/VAMP8/COL1A2/COL1A1	2.16663868929396
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	6/148	168/9376	2.26254826254826	GLUL/FTH1/FTL/CAMK2D/TNF/HSP90AB1	2.09113791834877
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	4/148	88/9376	2.87960687960688	C5AR1/TFPI/CLU/C1QA	2.2434167680413
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/148	89/9376	2.84725174612815	FN1/ITGA5/COL1A2/COL1A1	2.21741034468481
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/148	54/9376	3.51951951951952	HLA-C/CGA/TG	2.35137968047785
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	5/148	130/9376	2.43659043659044	FOS/JUN/NFKBIA/COL1A2/COL1A1	2.08876896247437
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	4/148	93/9376	2.72478930543447	EGR1/JUN/CGA/CAMK2D	2.11687908808668
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	4/148	93/9376	2.72478930543447	FN1/NFKBIA/GADD45G/CDKN1A	2.11687908808668
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/148	100/9376	2.53405405405405	CD9/ITGA5/TNF/IL6	1.95309332479956
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	5/148	144/9376	2.1996996996997	C5AR1/NFKBIA/TNF/C1QA/IL6	1.83725146037116
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	4/148	103/9376	2.46024665442141	SLC36A1/SLC7A8/COL1A2/COL1A1	1.88711082264789
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	9/148	333/9376	1.71219868517166	ISG15/HLA-C/FN1/ITGA5/MX1/TNF/CDKN1A/COL1A2/COL1A1	1.67582907837672
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	3/148	65/9376	2.92390852390852	CGA/KISS1/GABBR1	1.97108628804025
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/148	105/9376	2.41338481338481	CCL4/NFKBIA/GADD45G/TNF	1.844397320193
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/148	105/9376	2.41338481338481	UBC/JUN/GABARAPL1/CITED2	1.844397320193
NA	NA	hsa04981	Folate transport and metabolism	2/148	31/9376	4.0871839581517	ABCC3/DHFR	2.18030075857654
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/148	66/9376	2.87960687960688	JUN/TNF/IL6	1.94055902137838
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	4/148	106/9376	2.39061703212647	HSP90B1/NFKBIA/CDKN1A/HSP90AB1	1.82340571985286
Cellular Processes	Cell motility	hsa04814	Motor proteins	6/148	194/9376	1.95932014488716	ACTB/ACTG1/TPM4/MYL6/TUBB4B/DYNC1I1	1.70985187160929
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	4/148	110/9376	2.3036855036855	HMOX1/CAMK2D/CDKN1A/IL6	1.74174965843486
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	3/148	70/9376	2.71505791505792	NFKBIA/TNF/SOCS3	1.82393345364205
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	8/148	298/9376	1.70070741882822	CSH1/CCL3/CSH2/CCL2/CCL4/CSHL1/TNF/IL6	1.55672701274031
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	3/148	71/9376	2.67681766273316	FOS/CGA/SOCS3	1.7960545730825
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	3/148	72/9376	2.63963963963964	ISG15/NFKBIA/TNF	1.76865248870299
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/148	253/9376	1.7528041875868	ACTB/UBC/JUN/ACTG1/NFKBIA/ITGA5/TNF	1.53722044657505
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/148	37/9376	3.42439737034332	TNF/IL6	1.8711869569684
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/148	76/9376	2.50071123755334	ACTB/ACTG1/CAMK2D	1.66350901760865
Human Diseases	Cancer: specific types	hsa05214	Glioma	3/148	76/9376	2.50071123755334	CAMK2D/GADD45G/CDKN1A	1.66350901760865
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	3/148	77/9376	2.46823446823447	NFKBIA/GADD45G/CDKN1A	1.63826954173447
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	6/148	214/9376	1.77620611265471	FOS/HLA-C/JUN/CALR/NFKBIA/TNF	1.45462653102325
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	2/148	39/9376	3.24878724878725	DHFR/MAT2A	1.78213129688202
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/148	39/9376	3.24878724878725	HLA-C/TNF	1.78213129688202
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	4/148	122/9376	2.07709348692955	FOS/JUN/NFKBIA/TNF	1.516461086563
NA	NA	hsa04382	Cornified envelope formation	6/148	217/9376	1.7516502677793	S100A10/S100A8/S100A6/S100A4/S100A11/PLEC	1.41867970810225
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/148	217/9376	1.7516502677793	FOS/KLF4/JUN/HSP90B1/MGST1/HSP90AB1	1.41867970810225
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/148	83/9376	2.28980788016933	CCL4/NFKBIA/IL6	1.49468200712738
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/148	44/9376	2.87960687960688	HLA-C/TNF	1.5825910381319
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/148	86/9376	2.20993086109365	JUN/CAMK2D/CDKN1A	1.4274622298681
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	3/148	89/9376	2.13543880959611	GLUL/GABBR1/GABARAPL1	1.36296190675267
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/148	47/9376	2.69580218516389	TNF/SOCS3	1.47594194756988
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/148	90/9376	2.11171171171171	FOS/JUN/NFKBIA	1.34202868574339
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/148	91/9376	2.08850608850609	FOS/JUN/NFKBIA	1.32136654728703
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/148	49/9376	2.5857694429123	FOSB/JUN	1.40938550145308
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/148	93/9376	2.04359197907585	FOS/JUN/NFKBIA	1.2808277683773
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/148	51/9376	2.48436671966084	ACTB/ACTG1	1.34606049790794
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/148	52/9376	2.43659043659044	CGA/CYP19A1	1.31551623867318
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/148	98/9376	1.93932708218423	NR4A2/CAMK2D/NR4A1	1.18376474218719
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/148	99/9376	1.91973791973792	FOS/JUN/CDKN1A	1.16503940388501
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	4/148	148/9376	1.71219868517166	FOS/JUN/GADD45G/CDKN1A	1.10596385927443
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	5/148	201/9376	1.57590426247143	DUSP6/PPARG/GADD45G/CDKN1A/IL6	1.04522066639042
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	5/148	205/9376	1.54515491100857	HLA-C/JUN/EGR2/NFKBIA/CDKN1A	0.999427316665167
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	4/148	155/9376	1.63487358326068	CAMK2D/CRH/NR4A1/CDKN1A	1.00931516302348
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	8/148	370/9376	1.36975894813733	CSH1/C5AR1/CGA/CSH2/KISS1/CSHL1/GABBR1/CRH	0.919001639949558
Metabolism	Metabolism of other amino acids	hsa00450	Selenocompound metabolism	1/148	17/9376	3.72655007949126	TXNRD1	1.42490502803072
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/148	17/9376	3.72655007949126	GLUL	1.42490502803072
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/148	59/9376	2.14750343563903	GADD45G/CDKN1A	1.1197076762049
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/148	160/9376	1.58378378378378	HLA-C/ALCAM/SIGLEC1/VCAN	0.943199340334158
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/148	112/9376	1.6969111969112	HSPA8/NFKBIA/TNF	0.939614874611959
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/148	63/9376	2.01115401115401	GADD45G/CDKN1A	1.01977763995832
NA	NA	hsa04081	Hormone signaling	5/148	219/9376	1.44637788473405	CSH1/CGA/CSH2/CSHL1/CRH	0.846468542874686
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/148	169/9376	1.49944026867104	UBC/VAMP8/CTSL/GABARAPL1	0.829718052393998
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	4/148	170/9376	1.4906200317965	ACTB/JUN/ACTG1/MYL6	0.817517305375037
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/148	120/9376	1.58378378378378	JUN/NFKBIA/CAMK2D	0.815067694588951
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/148	70/9376	1.81003861003861	JUN/CDKN1A	0.861461590666594
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/148	23/9376	2.75440658049354	GLUL	1.06679605609243
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/148	71/9376	1.78454510848877	JUN/NFKBIA	0.840333365521688
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	4/148	181/9376	1.40002986411826	CLEC7A/CAMK2D/TNF/IL6	0.688206132592361
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/148	73/9376	1.73565346168086	GADD45G/CDKN1A	0.799071986206915
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/148	73/9376	1.73565346168086	GADD45G/CDKN1A	0.799071986206915
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/148	75/9376	1.68936936936937	GLUL/MAT2A	0.759067671014626
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/148	75/9376	1.68936936936937	CDKN1A/MGST1	0.759067671014626
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/148	75/9376	1.68936936936937	GADD45G/CDKN1A	0.759067671014626
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/148	77/9376	1.64548964548965	GADD45G/CDKN1A	0.720243291238273
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/148	78/9376	1.62439362439362	BTG2/BTG1	0.701251322456203
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/148	28/9376	2.26254826254826	B3GNT5	0.847286633853201
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/148	28/9376	2.26254826254826	DHFR	0.847286633853201
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/148	193/9376	1.31298137515754	CCL3/CCL2/CCL4/NFKBIA	0.556374939046285
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	4/148	195/9376	1.2995148995149	ACTB/C5AR1/CLEC7A/ACTG1	0.535246019722284
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/148	82/9376	1.54515491100857	UPP1/MGST1	0.627896733673599
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/148	31/9376	2.04359197907585	GLUL	0.737029090092098
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/148	31/9376	2.04359197907585	HSPA5	0.737029090092098
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/148	32/9376	1.97972972972973	GAA	0.703035999687594
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/148	32/9376	1.97972972972973	GABARAPL1	0.703035999687594
Human Diseases	Immune disease	hsa05310	Asthma	1/148	32/9376	1.97972972972973	TNF	0.703035999687594
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/148	323/9376	1.1768052882604	HMOX1/MCL1/VIM/ITGA5/CDKN1A/MARCKS	0.409508532007597
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/148	33/9376	1.91973791973792	VAMP8	0.670255815439374
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/148	93/9376	1.36239465271723	ACTB/ACTG1	0.444776448667917
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/148	36/9376	1.75975975975976	GAA	0.578384709131443
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/148	37/9376	1.71219868517166	GLUL	0.549685833999454
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/148	38/9376	1.66714082503556	SGK1	0.521849274683268
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/148	97/9376	1.30621342992477	FOS/CAMK2D	0.383903628433041
NA	NA	hsa04519	Cadherin signaling	7/148	404/9376	1.0976719293551	ACTB/VIM/ACTG1/CDH23/LHFPL2/NFKBIA/FMN1	0.25414321504835
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/148	99/9376	1.27982527982528	C5AR1/C1QA	0.354456927569646
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/148	99/9376	1.27982527982528	FOS/JUN	0.354456927569646
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/148	41/9376	1.54515491100857	CDKN1A	0.443013947025052
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/148	232/9376	1.09226467847158	ACTB/ACTG1/FN1/ITGA5	0.180207996924041
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/148	44/9376	1.43980343980344	RPN1	0.370305615458313
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/148	44/9376	1.43980343980344	DYNC1I1	0.370305615458313
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/148	45/9376	1.40780780780781	ABCC3	0.347264510288351
NA	NA	hsa04517	IgSF CAM signaling	5/148	299/9376	1.05938714634367	ACTB/ACTG1/ITGA5/MYL6/TUBB4B	0.132165951397354
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/148	110/9376	1.15184275184275	EMP3/TNF	0.202864924408734
NA	NA	hsa03272	Virion - Hepatitis viruses	1/148	48/9376	1.31981981981982	CD9	0.281315995867227
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/148	178/9376	1.06771940479806	JUN/CAMK2D/FOSL1	0.115515199859284
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/148	115/9376	1.10176263219741	FOS/CAMK2D	0.139050006333479
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/148	50/9376	1.26702702702703	IL6	0.239748125406543
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/148	116/9376	1.09226467847158	ACTB/ACTG1	0.126625646840746
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/148	117/9376	1.08292908292908	ACTB/ACTG1	0.114309007658638
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/148	52/9376	1.21829521829522	APOE	0.199897547121105
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/148	122/9376	1.03854674346478	ACTB/ACTG1	0.0542707176186677
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/148	54/9376	1.17317317317317	MAT2A	0.161616481812741
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/148	55/9376	1.15184275184275	PSAP	0.143023321481149
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/148	56/9376	1.13127413127413	RPN1	0.124775096167297
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/148	59/9376	1.07375171781951	UPP1	0.0719652438598759
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/148	59/9376	1.07375171781951	MGST1	0.0719652438598759
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/148	59/9376	1.07375171781951	CGA	0.0719652438598759
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/148	60/9376	1.05585585585586	CRH	0.0549657678088917
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/148	133/9376	0.952651900020321	HLA-C/TNF	-0.0696441436973474
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/148	133/9376	0.952651900020321	FOS/CAMK2D	-0.0696441436973474
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/148	62/9376	1.02179598953792	HSPA8	0.0218055488132918
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/148	65/9376	0.974636174636175	NR4A1	-0.0259857928615638
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/148	66/9376	0.95986895986896	CYP19A1	-0.0414324148355297
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/148	140/9376	0.905019305019305	EGR1/KLF2	-0.143390408406269
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/148	67/9376	0.945542557482856	CAMK2D	-0.0566507717880401
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/148	142/9376	0.892272554244385	UBC/SOCS3	-0.163809205072132
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/148	68/9376	0.931637519872814	DUSP6	-0.0716484471272175
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/148	143/9376	0.886032886032886	TNF/C1QA	-0.173915726199907
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/148	69/9376	0.918135526831179	TNF	-0.0864326567954237
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/148	70/9376	0.905019305019305	MGST1	-0.101010272308857
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/148	73/9376	0.867826730840429	MGST1	-0.143567538538434
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/148	73/9376	0.867826730840429	MX1	-0.143567538538434
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/148	150/9376	0.844684684684685	GADD45G/CDKN1A	-0.242837576538564
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/148	154/9376	0.822744822744823	DHFR/MAT2A	-0.280872638056817
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/148	154/9376	0.822744822744823	TPM4/CAMK2D	-0.280872638056817
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/148	157/9376	0.807023584093648	ACTB/ACTG1	-0.308798269440408
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/148	158/9376	0.801915839890523	GADD45G/CDKN1A	-0.317996721815796
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	2/148	158/9376	0.801915839890523	TNF/SGK1	-0.317996721815796
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/148	79/9376	0.801915839890523	MGST1	-0.223900251551635
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/148	80/9376	0.791891891891892	IL6	-0.236727460952303
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/148	85/9376	0.745310015898251	UPP1	-0.298712091104837
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/148	86/9376	0.736643620364551	GABBR1	-0.310704765877783
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/148	86/9376	0.736643620364551	CAMK2D	-0.310704765877783
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/148	89/9376	0.711812936532038	TUBB4B	-0.345934969111603
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/148	250/9376	0.760216216216216	HLA-C/HSPA8/CAV1	-0.486645020795661
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/148	90/9376	0.703903903903904	PPARG	-0.357439298796052
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/148	90/9376	0.703903903903904	ABCC3	-0.357439298796052
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/148	91/9376	0.696168696168696	GABBR1	-0.368828916200444
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/148	98/9376	0.646442360728075	MARCKS	-0.44556265398825
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/148	99/9376	0.63991263991264	CAMK2D	-0.456125548745719
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/148	101/9376	0.627241102488627	CAMK2D	-0.476973717893132
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/148	102/9376	0.621091679915209	SLC26A3	-0.487262943841927
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/148	103/9376	0.615061663605353	PABPN1	-0.497464793679146
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/148	191/9376	0.663364935616245	FOSB/CRH	-0.595249661350771
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/148	107/9376	0.592068704218237	CAMK2D	-0.53743404660391
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/148	108/9376	0.586586586586587	EEF1A1	-0.54722525409628
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/148	110/9376	0.575921375921376	HSP90AB1	-0.566577442604328
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/148	115/9376	0.550881316098707	DUSP1	-0.613682591462536
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/148	116/9376	0.546132339235788	GLUL	-0.62289585870145
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/148	212/9376	0.597654258031617	ACTB/ACTG1	-0.750390803261643
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/148	122/9376	0.519273371732388	PPARG	-0.6768244668535
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/148	125/9376	0.506810810810811	TNF	-0.702970203575319
Genetic Information Processing	Translation	hsa03010	Ribosome	2/148	222/9376	0.570732895057219	RPL35/RPL8	-0.819712099474722
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/148	134/9376	0.472771278741428	MYL6	-0.778450820759483
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/148	138/9376	0.45906776341559	CAMK2D	-0.810692454764401
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/148	138/9376	0.45906776341559	SOCS3	-0.810692454764401
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/148	144/9376	0.43993993993994	KLF4	-0.857690606656373
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/148	166/9376	0.381634646694888	RGS2	-1.01796320449639
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/148	184/9376	0.344300822561692	CAMK2D	-1.13755196634991
NA	NA	hsa04082	Neuroactive ligand signaling	1/148	199/9376	0.318348499253022	GABBR1	-1.23083906181511
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/148	243/9376	0.260705149594039	HSPA8	-1.47868882940781
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/148	254/9376	0.249414769099808	CAMK2D	-1.53579957112317
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	2/148	449/9376	0.282188647444772	CAMK2D/RGS2	-1.97398309334426