ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 11/216 68/18639 0.161764705882353 13.9589460784314 3.37240131558784e-10 1.87842753278243e-07 GO:0009055 electron transfer activity 12/216 116/18639 0.103448275862069 8.92672413793103 1.03195421179845e-08 2.87399247985869e-06 GO:0015078 proton transmembrane transporter activity 14/216 185/18639 0.0756756756756757 6.53018018018018 3.44336248966307e-08 6.39317635580776e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 11/216 118/18639 0.0932203389830508 8.0441384180791 1.26919085721316e-07 1.76734826866932e-05 GO:0140313 molecular sequestering activity 8/216 55/18639 0.145454545454545 12.5515151515152 2.17891098443181e-07 2.42730683665703e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/216 41/18639 0.170731707317073 14.7327235772358 4.097463241929e-07 3.80381170959076e-05 GO:0031625 ubiquitin protein ligase binding 16/216 302/18639 0.0529801324503311 4.57174392935982 5.01326873421618e-07 3.82795288840408e-05 GO:0015399 primary active transmembrane transporter activity 12/216 166/18639 0.072289156626506 6.23795180722892 5.49795746988019e-07 3.82795288840408e-05 GO:0003954 NADH dehydrogenase activity 7/216 44/18639 0.159090909090909 13.7282196969697 6.78131751502477e-07 4.19688206207644e-05 GO:0044389 ubiquitin-like protein ligase binding 16/216 322/18639 0.0496894409937888 4.28778467908903 1.17041259673805e-06 6.51919816383093e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/216 58/18639 0.120689655172414 10.4145114942529 4.6377936652507e-06 0.000234841006504058 GO:0022804 active transmembrane transporter activity 18/216 457/18639 0.0393873085339169 3.39879649890591 6.71279537568555e-06 0.000311585585354738 GO:0044548 S100 protein binding 4/216 14/18639 0.285714285714286 24.6547619047619 1.60296247327886e-05 0.000686807767397175 GO:0042277 peptide binding 12/216 249/18639 0.0481927710843374 4.15863453815261 3.53509941424615e-05 0.00140646455266793 GO:0048306 calcium-dependent protein binding 7/216 80/18639 0.0875 7.55052083333333 3.95045908028723e-05 0.00146693713847999 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/216 88/18639 0.0795454545454545 6.86410984848485 7.30096430180521e-05 0.00254164819756594 GO:0051082 unfolded protein binding 8/216 121/18639 0.0661157024793388 5.70523415977961 8.37507149828852e-05 0.00273949261781929 GO:1901682 sulfur compound transmembrane transporter activity 6/216 63/18639 0.0952380952380952 8.21825396825397 8.85293844178587e-05 0.00273949261781929 GO:0038024 cargo receptor activity 6/216 65/18639 0.0923076923076923 7.96538461538462 0.000105572600578443 0.003094944132747 GO:0005131 growth hormone receptor binding 3/216 10/18639 0.3 25.8875 0.000173444065710565 0.00460039736194213 GO:0030957 Tat protein binding 3/216 10/18639 0.3 25.8875 0.000173444065710565 0.00460039736194213 GO:0050750 low-density lipoprotein particle receptor binding 4/216 26/18639 0.153846153846154 13.275641025641 0.000214653479074362 0.00543463581110999 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13/216 349/18639 0.0372492836676218 3.21430276981853 0.000227564932850694 0.00551102902599288 GO:0046332 SMAD binding 6/216 79/18639 0.0759493670886076 6.55379746835443 0.000310601661867525 0.0072085469025088 GO:0001540 amyloid-beta binding 6/216 83/18639 0.072289156626506 6.23795180722892 0.000405908047619829 0.00904363130096978 GO:0070325 lipoprotein particle receptor binding 4/216 31/18639 0.129032258064516 11.1344086021505 0.000431755194119791 0.00924952473556628 GO:0071813 lipoprotein particle binding 4/216 32/18639 0.125 10.7864583333333 0.000488986008801275 0.00972732881793966 GO:0071814 protein-lipid complex binding 4/216 32/18639 0.125 10.7864583333333 0.000488986008801275 0.00972732881793966 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/216 484/18639 0.0309917355371901 2.67432851239669 0.000544587860874497 0.00990773156119893 GO:0045296 cadherin binding 12/216 334/18639 0.0359281437125748 3.10029940119761 0.000545372971807052 0.00990773156119893 GO:0140311 protein sequestering activity 4/216 33/18639 0.121212121212121 10.459595959596 0.00055141773500389 0.00990773156119893 GO:0051427 hormone receptor binding 4/216 34/18639 0.117647058823529 10.1519607843137 0.000619310140085477 0.0100444151958074 GO:0004129 cytochrome-c oxidase activity 3/216 15/18639 0.2 17.2583333333333 0.000630066301004849 0.0100444151958074 GO:0005041 low-density lipoprotein particle receptor activity 3/216 15/18639 0.2 17.2583333333333 0.000630066301004849 0.0100444151958074 GO:0001216 DNA-binding transcription activator activity 15/216 491/18639 0.0305498981670061 2.6362016293279 0.000631157148749118 0.0100444151958074 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/216 16/18639 0.1875 16.1796875 0.000768861930695349 0.0114143963205162 GO:0022858 alanine transmembrane transporter activity 3/216 16/18639 0.1875 16.1796875 0.000768861930695349 0.0114143963205162 GO:0005201 extracellular matrix structural constituent 8/216 168/18639 0.0476190476190476 4.10912698412698 0.000778720036229114 0.0114143963205162 GO:0030169 low-density lipoprotein particle binding 3/216 17/18639 0.176470588235294 15.2279411764706 0.000925671255116124 0.0132204843358893 GO:0030228 lipoprotein particle receptor activity 3/216 18/18639 0.166666666666667 14.3819444444444 0.00110135574480737 0.0149623207282367 GO:0098641 cadherin binding involved in cell-cell adhesion 3/216 18/18639 0.166666666666667 14.3819444444444 0.00110135574480737 0.0149623207282367 GO:0140662 ATP-dependent protein folding chaperone 4/216 40/18639 0.1 8.62916666666667 0.00115601342660203 0.0152432148866569 GO:0004857 enzyme inhibitor activity 13/216 416/18639 0.03125 2.69661458333333 0.00117676524259649 0.0152432148866569 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/216 41/18639 0.0975609756097561 8.41869918699187 0.00126947750780822 0.0160507594765029 GO:0034987 immunoglobulin receptor binding 3/216 19/18639 0.157894736842105 13.625 0.00129673999361334 0.0160507594765029 GO:0005126 cytokine receptor binding 10/216 275/18639 0.0363636363636364 3.13787878787879 0.00143209209575294 0.0173407673333562 GO:0048156 tau protein binding 4/216 43/18639 0.0930232558139535 8.02713178294574 0.00151935398546633 0.0180059610618031 GO:0046943 carboxylic acid transmembrane transporter activity 8/216 188/18639 0.0425531914893617 3.67198581560284 0.00160295811613216 0.0184645043237652 GO:0030547 signaling receptor inhibitor activity 4/216 44/18639 0.0909090909090909 7.84469696969697 0.00165628885041386 0.0184645043237652 GO:0005342 organic acid transmembrane transporter activity 8/216 189/18639 0.0423280423280423 3.65255731922399 0.00165749589979939 0.0184645043237652 GO:0140297 DNA-binding transcription factor binding 14/216 488/18639 0.0286885245901639 2.4755806010929 0.00172353384753543 0.0188236931975928 GO:0044183 protein folding chaperone 5/216 75/18639 0.0666666666666667 5.75277777777778 0.00178375615084041 0.0191067726157329 GO:0005200 structural constituent of cytoskeleton 6/216 112/18639 0.0535714285714286 4.62276785714286 0.001950376296177 0.0204973508862375 GO:0033218 amide binding 9/216 247/18639 0.0364372469635627 3.14423076923077 0.00242064701852411 0.0249685257281098 GO:0004860 protein kinase inhibitor activity 5/216 84/18639 0.0595238095238095 5.13640873015873 0.00293427954467196 0.0297162492069506 GO:0070412 R-SMAD binding 3/216 26/18639 0.115384615384615 9.95673076923077 0.00327795077213152 0.0326039032156653 GO:0005044 scavenger receptor activity 3/216 27/18639 0.111111111111111 9.58796296296296 0.00365648103453046 0.0357308760742714 GO:0019210 kinase inhibitor activity 5/216 90/18639 0.0555555555555556 4.79398148148148 0.00395084594600252 0.0379417446883345 GO:0031072 heat shock protein binding 6/216 131/18639 0.0458015267175573 3.95229007633588 0.00425325200074143 0.0401535824476776 GO:0005179 hormone activity 6/216 132/18639 0.0454545454545455 3.92234848484848 0.00441373404466454 0.0409741643813025 GO:0004879 nuclear receptor activity 4/216 59/18639 0.0677966101694915 5.85028248587571 0.00485255888575421 0.0434864394611874 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/216 30/18639 0.1 8.62916666666667 0.00494767644031187 0.0434864394611874 GO:0048019 receptor antagonist activity 3/216 30/18639 0.1 8.62916666666667 0.00494767644031187 0.0434864394611874 GO:0002020 protease binding 6/216 136/18639 0.0441176470588235 3.80698529411765 0.005100635249169 0.0434864394611874 GO:0044325 transmembrane transporter binding 6/216 136/18639 0.0441176470588235 3.80698529411765 0.005100635249169 0.0434864394611874 GO:0098531 ligand-modulated transcription factor activity 4/216 60/18639 0.0666666666666667 5.75277777777778 0.00515279174944052 0.0434864394611874 GO:0015187 glycine transmembrane transporter activity 2/216 10/18639 0.2 17.2583333333333 0.00565810776201685 0.0456748699049766 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/216 10/18639 0.2 17.2583333333333 0.00565810776201685 0.0456748699049766 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/216 10/18639 0.2 17.2583333333333 0.00565810776201685 0.0456748699049766 GO:0015179 L-amino acid transmembrane transporter activity 4/216 62/18639 0.0645161290322581 5.56720430107527 0.00579005901645115 0.0460723267451899 GO:0015171 amino acid transmembrane transporter activity 5/216 102/18639 0.0490196078431373 4.22998366013072 0.00669990975972436 0.0496447649712708 GO:0000099 sulfur amino acid transmembrane transporter activity 2/216 11/18639 0.181818181818182 15.6893939393939 0.0068629208308579 0.0496447649712708 GO:0008199 ferric iron binding 2/216 11/18639 0.181818181818182 15.6893939393939 0.0068629208308579 0.0496447649712708 GO:0048407 platelet-derived growth factor binding 2/216 11/18639 0.181818181818182 15.6893939393939 0.0068629208308579 0.0496447649712708 GO:0050786 RAGE receptor binding 2/216 11/18639 0.181818181818182 15.6893939393939 0.0068629208308579 0.0496447649712708 GO:0050998 nitric-oxide synthase binding 2/216 11/18639 0.181818181818182 15.6893939393939 0.0068629208308579 0.0496447649712708 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/216 11/18639 0.181818181818182 15.6893939393939 0.0068629208308579 0.0496447649712708 GO:0005154 epidermal growth factor receptor binding 3/216 35/18639 0.0857142857142857 7.39642857142857 0.00764522797665342 0.0545947690127686 GO:0001664 G protein-coupled receptor binding 9/216 297/18639 0.0303030303030303 2.61489898989899 0.00797554933343636 0.0555165304188071 GO:1990841 promoter-specific chromatin binding 4/216 68/18639 0.0588235294117647 5.07598039215686 0.00801127400946974 0.0555165304188071 GO:0004859 phospholipase inhibitor activity 2/216 12/18639 0.166666666666667 14.3819444444444 0.00817299011551558 0.0555165304188071 GO:0035259 nuclear glucocorticoid receptor binding 2/216 12/18639 0.166666666666667 14.3819444444444 0.00817299011551558 0.0555165304188071 GO:0097110 scaffold protein binding 4/216 70/18639 0.0571428571428571 4.93095238095238 0.00886008820821801 0.0591745444344709 GO:0043394 proteoglycan binding 3/216 37/18639 0.0810810810810811 6.99662162162162 0.00892398874774785 0.0591745444344709 GO:0004222 metalloendopeptidase activity 5/216 110/18639 0.0454545454545455 3.92234848484848 0.00914392262374807 0.0599195870756197 GO:0051015 actin filament binding 7/216 209/18639 0.0334928229665072 2.89015151515152 0.0111373541876746 0.0721337939829624 GO:0005178 integrin binding 6/216 161/18639 0.0372670807453416 3.21583850931677 0.0112826415169 0.0722348428150953 GO:0008307 structural constituent of muscle 3/216 42/18639 0.0714285714285714 6.16369047619048 0.012640396669446 0.0777913395113688 GO:0017081 chloride channel regulator activity 2/216 15/18639 0.133333333333333 11.5055555555556 0.0127091775503313 0.0777913395113688 GO:0031386 protein tag activity 2/216 15/18639 0.133333333333333 11.5055555555556 0.0127091775503313 0.0777913395113688 GO:0141047 molecular tag activity 2/216 15/18639 0.133333333333333 11.5055555555556 0.0127091775503313 0.0777913395113688 GO:0008514 organic anion transmembrane transporter activity 8/216 269/18639 0.0297397769516729 2.56629491945477 0.0133974349417278 0.0798434308830283 GO:0033293 monocarboxylic acid binding 4/216 79/18639 0.0506329113924051 4.36919831223629 0.0134005101529373 0.0798434308830283 GO:0008200 ion channel inhibitor activity 3/216 43/18639 0.0697674418604651 6.0203488372093 0.0134744748707445 0.0798434308830283 GO:0016248 channel inhibitor activity 3/216 44/18639 0.0681818181818182 5.88352272727273 0.0143392201893052 0.0828519520466582 GO:0055102 lipase inhibitor activity 2/216 16/18639 0.125 10.7864583333333 0.014414936924565 0.0828519520466582 GO:0003779 actin binding 11/216 443/18639 0.0248306997742664 2.14268246802107 0.0145491372423584 0.0828519520466582 GO:0015101 organic cation transmembrane transporter activity 4/216 81/18639 0.0493827160493827 4.26131687242798 0.0145771836635054 0.0828519520466582 GO:0008009 chemokine activity 3/216 45/18639 0.0666666666666667 5.75277777777778 0.0152347667796771 0.0848576509628013 GO:0141110 transporter inhibitor activity 3/216 45/18639 0.0666666666666667 5.75277777777778 0.0152347667796771 0.0848576509628013 GO:0030291 protein serine/threonine kinase inhibitor activity 3/216 46/18639 0.0652173913043478 5.62771739130435 0.016161230785937 0.0868357948464789 GO:0036041 long-chain fatty acid binding 2/216 17/18639 0.117647058823529 10.1519607843137 0.0162135056804916 0.0868357948464789 GO:0046965 nuclear retinoid X receptor binding 2/216 17/18639 0.117647058823529 10.1519607843137 0.0162135056804916 0.0868357948464789 GO:0051787 misfolded protein binding 2/216 17/18639 0.117647058823529 10.1519607843137 0.0162135056804916 0.0868357948464789 GO:0030246 carbohydrate binding 8/216 280/18639 0.0285714285714286 2.46547619047619 0.0166676117964546 0.0884177121011927 GO:0005504 fatty acid binding 3/216 47/18639 0.0638297872340425 5.50797872340426 0.0171187108590984 0.0899539806463943 GO:0051087 protein-folding chaperone binding 5/216 134/18639 0.0373134328358209 3.21983830845771 0.0200058082676134 0.104066074649382 GO:0048020 CCR chemokine receptor binding 3/216 50/18639 0.06 5.1775 0.0201779821582285 0.104066074649382 GO:0031406 carboxylic acid binding 6/216 187/18639 0.0320855614973262 2.76871657754011 0.0219903981975548 0.11237295225723 GO:0043177 organic acid binding 6/216 189/18639 0.0317460317460317 2.73941798941799 0.023025195094269 0.116591215159162 GO:0072542 protein phosphatase activator activity 2/216 21/18639 0.0952380952380952 8.21825396825397 0.0242893094070549 0.121884192249816 GO:0098632 cell-cell adhesion mediator activity 3/216 55/18639 0.0545454545454545 4.70681818181818 0.0259015868067728 0.128814141530111 GO:0099186 structural constituent of postsynapse 2/216 23/18639 0.0869565217391304 7.5036231884058 0.0288246776514512 0.14208270311379 GO:0015459 potassium channel regulator activity 3/216 59/18639 0.0508474576271186 4.38771186440678 0.0310418856805513 0.149857699777085 GO:0005540 hyaluronic acid binding 2/216 24/18639 0.0833333333333333 7.19097222222222 0.0312091439392134 0.149857699777085 GO:0035035 histone acetyltransferase binding 2/216 24/18639 0.0833333333333333 7.19097222222222 0.0312091439392134 0.149857699777085 GO:0019211 phosphatase activator activity 2/216 25/18639 0.08 6.90333333333333 0.0336686787693916 0.158366593186376 GO:0042974 nuclear retinoic acid receptor binding 2/216 25/18639 0.08 6.90333333333333 0.0336686787693916 0.158366593186376 GO:0005516 calmodulin binding 6/216 207/18639 0.0289855072463768 2.5012077294686 0.0338341554563352 0.158366593186376 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/216 26/18639 0.0769230769230769 6.63782051282051 0.03620123943583 0.166645374923614 GO:0008198 ferrous iron binding 2/216 26/18639 0.0769230769230769 6.63782051282051 0.03620123943583 0.166645374923614 GO:0099106 ion channel regulator activity 5/216 160/18639 0.03125 2.69661458333333 0.0387855079031016 0.175725892683896 GO:0023026 MHC class II protein complex binding 2/216 27/18639 0.0740740740740741 6.39197530864197 0.0388048201079339 0.175725892683896 GO:0008083 growth factor activity 5/216 162/18639 0.0308641975308642 2.66332304526749 0.0405606484972049 0.182195816233412 GO:0005416 amino acid:monoatomic cation symporter activity 2/216 29/18639 0.0689655172413793 5.95114942528736 0.0442171990900261 0.197031839145156 GO:0016247 channel regulator activity 5/216 168/18639 0.0297619047619048 2.56820436507936 0.0461785684088747 0.2041385920932 GO:0001965 G-protein alpha-subunit binding 2/216 30/18639 0.0666666666666667 5.75277777777778 0.0470221649935771 0.204619889854863 GO:0098918 structural constituent of synapse 2/216 30/18639 0.0666666666666667 5.75277777777778 0.0470221649935771 0.204619889854863 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/216 70/18639 0.0428571428571429 3.69821428571429 0.0477044761413771 0.205510477647379 GO:0141108 transporter regulator activity 5/216 170/18639 0.0294117647058824 2.53799019607843 0.0481491874889214 0.205510477647379 GO:0061134 peptidase regulator activity 6/216 226/18639 0.0265486725663717 2.29092920353982 0.0483337030014483 0.205510477647379 GO:0019207 kinase regulator activity 7/216 287/18639 0.024390243902439 2.10467479674797 0.0502587750460096 0.212076800762328 GO:0042379 chemokine receptor binding 3/216 72/18639 0.0416666666666667 3.59548611111111 0.0511217136728543 0.214096199366766 GO:0071889 14-3-3 protein binding 2/216 33/18639 0.0606060606060606 5.22979797979798 0.0558099011885333 0.231985932552336 GO:0003725 double-stranded RNA binding 3/216 75/18639 0.04 3.45166666666667 0.0564637730629743 0.232965345156124 GO:0098631 cell adhesion mediator activity 3/216 76/18639 0.0394736842105263 3.40625 0.0583012402917914 0.238777873842116 GO:0015035 protein-disulfide reductase activity 2/216 34/18639 0.0588235294117647 5.07598039215686 0.0588574377483004 0.239296297998564 GO:0008237 metallopeptidase activity 5/216 184/18639 0.0271739130434783 2.34488224637681 0.063321595578429 0.255580643023079 GO:0023023 MHC protein complex binding 2/216 37/18639 0.0540540540540541 4.66441441441441 0.0683306860799336 0.273814331989374 GO:0015297 antiporter activity 4/216 135/18639 0.0296296296296296 2.55679012345679 0.0721739449836682 0.287149195399308 GO:0016922 nuclear receptor binding 4/216 137/18639 0.0291970802919708 2.51946472019465 0.0752814213864378 0.297388310015928 GO:0019887 protein kinase regulator activity 6/216 255/18639 0.0235294117647059 2.03039215686274 0.0769143274070191 0.299313438013993 GO:0016209 antioxidant activity 3/216 86/18639 0.0348837209302326 3.01017441860465 0.0781751506317954 0.299313438013993 GO:0015036 disulfide oxidoreductase activity 2/216 40/18639 0.05 4.31458333333333 0.0782651992257823 0.299313438013993 GO:0071855 neuropeptide receptor binding 2/216 40/18639 0.05 4.31458333333333 0.0782651992257823 0.299313438013993 GO:0070851 growth factor receptor binding 4/216 139/18639 0.0287769784172662 2.48321342925659 0.0784555869839193 0.299313438013993 GO:0017080 sodium channel regulator activity 2/216 41/18639 0.0487804878048781 4.20934959349594 0.0816717821146962 0.307372855661391 GO:0042287 MHC protein binding 2/216 41/18639 0.0487804878048781 4.20934959349594 0.0816717821146962 0.307372855661391 GO:0035198 miRNA binding 2/216 42/18639 0.0476190476190476 4.10912698412698 0.0851233513869587 0.313998057765139 GO:0042056 chemoattractant activity 2/216 42/18639 0.0476190476190476 4.10912698412698 0.0851233513869587 0.313998057765139 GO:0048487 beta-tubulin binding 2/216 42/18639 0.0476190476190476 4.10912698412698 0.0851233513869587 0.313998057765139 GO:0072341 modified amino acid binding 3/216 91/18639 0.032967032967033 2.84478021978022 0.0890810611188761 0.326435204231671 GO:0003924 GTPase activity 7/216 331/18639 0.0211480362537764 1.82489929506546 0.0912170568856119 0.331165331819143 GO:0001046 core promoter sequence-specific DNA binding 2/216 44/18639 0.0454545454545455 3.92234848484848 0.0921555232171762 0.331165331819143 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/216 44/18639 0.0454545454545455 3.92234848484848 0.0921555232171762 0.331165331819143 GO:0042605 peptide antigen binding 2/216 45/18639 0.0444444444444444 3.83518518518519 0.0957332328189203 0.341816735129094 GO:0004867 serine-type endopeptidase inhibitor activity 3/216 95/18639 0.0315789473684211 2.725 0.0982382545311673 0.34852680110739 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/216 46/18639 0.0434782608695652 3.7518115942029 0.0993501420022377 0.350240690476243 GO:0005506 iron ion binding 4/216 154/18639 0.025974025974026 2.24134199134199 0.104314327924466 0.362712326856982 GO:0038187 pattern recognition receptor activity 2/216 48/18639 0.0416666666666667 3.59548611111111 0.106696071562726 0.362712326856982 GO:0004955 prostaglandin receptor activity 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0005381 iron ion transmembrane transporter activity 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0005522 profilin binding 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0005528 FK506 binding 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0019531 oxalate transmembrane transporter activity 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0043208 glycosphingolipid binding 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0070513 death domain binding 1/216 10/18639 0.1 8.62916666666667 0.110050957340808 0.362712326856982 GO:0015291 secondary active transmembrane transporter activity 6/216 287/18639 0.0209059233449477 1.80400696864112 0.117474366089415 0.372477538180189 GO:0004866 endopeptidase inhibitor activity 4/216 161/18639 0.0248447204968944 2.14389233954451 0.117556875979157 0.372477538180189 GO:0002162 dystroglycan binding 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0004954 prostanoid receptor activity 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0008271 secondary active sulfate transmembrane transporter activity 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0010854 adenylate cyclase regulator activity 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0015173 aromatic amino acid transmembrane transporter activity 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0019215 intermediate filament binding 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0097493 structural molecule activity conferring elasticity 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/216 11/18639 0.0909090909090909 7.84469696969697 0.120369760991803 0.372477538180189 GO:0005080 protein kinase C binding 2/216 52/18639 0.0384615384615385 3.31891025641026 0.121799418450137 0.372959965955649 GO:0008013 beta-catenin binding 3/216 106/18639 0.0283018867924528 2.44221698113208 0.125233614885014 0.372959965955649 GO:0005544 calcium-dependent phospholipid binding 2/216 53/18639 0.0377358490566038 3.2562893081761 0.125653577037058 0.372959965955649 GO:0019888 protein phosphatase regulator activity 3/216 107/18639 0.0280373831775701 2.41939252336449 0.127809463799731 0.372959965955649 GO:0015485 cholesterol binding 2/216 54/18639 0.037037037037037 3.19598765432099 0.129536623708479 0.372959965955649 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/216 54/18639 0.037037037037037 3.19598765432099 0.129536623708479 0.372959965955649 GO:0004875 complement receptor activity 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0005049 nuclear export signal receptor activity 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0005527 macrolide binding 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0016208 AMP binding 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0035497 cAMP response element binding 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0097677 STAT family protein binding 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0140900 chloride:bicarbonate antiporter activity 1/216 12/18639 0.0833333333333333 7.19097222222222 0.130569467435101 0.372959965955649 GO:0030414 peptidase inhibitor activity 4/216 169/18639 0.0236686390532544 2.04240631163708 0.133535453787525 0.376701022630391 GO:0005125 cytokine activity 5/216 234/18639 0.0213675213675214 1.84383903133903 0.136482278828275 0.376701022630391 GO:0170055 lipid transmembrane transporter activity 2/216 56/18639 0.0357142857142857 3.08184523809524 0.137384689924671 0.376701022630391 GO:0046982 protein heterodimerization activity 7/216 369/18639 0.018970189701897 1.63696928635953 0.138143032046922 0.376701022630391 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0005172 vascular endothelial growth factor receptor binding 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0005542 folic acid binding 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0031432 titin binding 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0035325 Toll-like receptor binding 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0039706 co-receptor binding 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0071714 icosanoid transmembrane transporter activity 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0071837 HMG box domain binding 1/216 13/18639 0.0769230769230769 6.63782051282051 0.140651444942699 0.376701022630391 GO:0004601 peroxidase activity 2/216 57/18639 0.0350877192982456 3.02777777777778 0.141347421417867 0.376701022630391 GO:0016504 peptidase activator activity 2/216 57/18639 0.0350877192982456 3.02777777777778 0.141347421417867 0.376701022630391 GO:0061980 regulatory RNA binding 2/216 58/18639 0.0344827586206897 2.97557471264368 0.145334464147217 0.377899525674433 GO:0001221 transcription coregulator binding 3/216 115/18639 0.0260869565217391 2.25108695652174 0.149069200606281 0.377899525674433 GO:0017124 SH3 domain binding 3/216 115/18639 0.0260869565217391 2.25108695652174 0.149069200606281 0.377899525674433 GO:0001786 phosphatidylserine binding 2/216 59/18639 0.0338983050847458 2.92514124293785 0.149344730058327 0.377899525674433 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/216 59/18639 0.0338983050847458 2.92514124293785 0.149344730058327 0.377899525674433 GO:0070063 RNA polymerase binding 2/216 59/18639 0.0338983050847458 2.92514124293785 0.149344730058327 0.377899525674433 GO:0005161 platelet-derived growth factor receptor binding 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:0005313 L-glutamate transmembrane transporter activity 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:0005545 1-phosphatidylinositol binding 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:0008559 ABC-type xenobiotic transporter activity 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:0015926 glucosidase activity 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:0061665 SUMO ligase activity 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:1990825 sequence-specific mRNA binding 1/216 14/18639 0.0714285714285714 6.16369047619048 0.150617046139541 0.377899525674433 GO:0019208 phosphatase regulator activity 3/216 117/18639 0.0256410256410256 2.21260683760684 0.154553614938282 0.383607114837625 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/216 61/18639 0.0327868852459016 2.8292349726776 0.157430687539139 0.383607114837625 GO:0004953 icosanoid receptor activity 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0005523 tropomyosin binding 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0015116 sulfate transmembrane transporter activity 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0033130 acetylcholine receptor binding 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0045504 dynein heavy chain binding 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0048531 beta-1,3-galactosyltransferase activity 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0120283 protein serine/threonine kinase binding 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0140161 monocarboxylate:sodium symporter activity 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0140776 protein-containing complex destabilizing activity 1/216 15/18639 0.0666666666666667 5.75277777777778 0.160467608181628 0.383607114837625 GO:0061135 endopeptidase regulator activity 4/216 184/18639 0.0217391304347826 1.87590579710145 0.165690009207275 0.394398868070307 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/216 16/18639 0.0625 5.39322916666667 0.170204452932098 0.398335631441927 GO:0008142 oxysterol binding 1/216 16/18639 0.0625 5.39322916666667 0.170204452932098 0.398335631441927 GO:0015378 sodium:chloride symporter activity 1/216 16/18639 0.0625 5.39322916666667 0.170204452932098 0.398335631441927 GO:0016722 oxidoreductase activity, acting on metal ions 1/216 16/18639 0.0625 5.39322916666667 0.170204452932098 0.398335631441927 GO:0008429 phosphatidylethanolamine binding 1/216 17/18639 0.0588235294117647 5.07598039215686 0.179828887135323 0.412200370923354 GO:0030548 acetylcholine receptor regulator activity 1/216 17/18639 0.0588235294117647 5.07598039215686 0.179828887135323 0.412200370923354 GO:0048038 quinone binding 1/216 17/18639 0.0588235294117647 5.07598039215686 0.179828887135323 0.412200370923354 GO:0070402 NADPH binding 1/216 17/18639 0.0588235294117647 5.07598039215686 0.179828887135323 0.412200370923354 GO:1990226 histone methyltransferase binding 1/216 17/18639 0.0588235294117647 5.07598039215686 0.179828887135323 0.412200370923354 GO:0031490 chromatin DNA binding 3/216 128/18639 0.0234375 2.0224609375 0.18576825426778 0.41521105055939 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/216 128/18639 0.0234375 2.0224609375 0.18576825426778 0.41521105055939 GO:0032934 sterol binding 2/216 68/18639 0.0294117647058824 2.53799019607843 0.186313121843868 0.41521105055939 GO:0000900 mRNA regulatory element binding translation repressor activity 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0003746 translation elongation factor activity 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0015172 acidic amino acid transmembrane transporter activity 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0015373 monoatomic anion:sodium symporter activity 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0050811 GABA receptor binding 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0099602 neurotransmitter receptor regulator activity 1/216 18/18639 0.0555555555555556 4.79398148148148 0.189342202589022 0.41521105055939 GO:0004175 endopeptidase activity 7/216 405/18639 0.0172839506172839 1.49146090534979 0.191469195005238 0.4182287906585 GO:0015245 fatty acid transmembrane transporter activity 1/216 19/18639 0.0526315789473684 4.54166666666667 0.198745676314427 0.425774391181291 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/216 19/18639 0.0526315789473684 4.54166666666667 0.198745676314427 0.425774391181291 GO:0030506 ankyrin binding 1/216 19/18639 0.0526315789473684 4.54166666666667 0.198745676314427 0.425774391181291 GO:0043395 heparan sulfate proteoglycan binding 1/216 19/18639 0.0526315789473684 4.54166666666667 0.198745676314427 0.425774391181291 GO:0097001 ceramide binding 1/216 19/18639 0.0526315789473684 4.54166666666667 0.198745676314427 0.425774391181291 GO:0005518 collagen binding 2/216 72/18639 0.0277777777777778 2.39699074074074 0.203134488736326 0.433509234582887 GO:0005096 GTPase activator activity 5/216 271/18639 0.018450184501845 1.59209717097171 0.206861818273356 0.434002239301731 GO:0001972 retinoic acid binding 1/216 20/18639 0.05 4.31458333333333 0.208040570724528 0.434002239301731 GO:0010851 cyclase regulator activity 1/216 20/18639 0.05 4.31458333333333 0.208040570724528 0.434002239301731 GO:0016004 phospholipase activator activity 1/216 20/18639 0.05 4.31458333333333 0.208040570724528 0.434002239301731 GO:0042288 MHC class I protein binding 1/216 20/18639 0.05 4.31458333333333 0.208040570724528 0.434002239301731 GO:0043024 ribosomal small subunit binding 1/216 20/18639 0.05 4.31458333333333 0.208040570724528 0.434002239301731 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/216 21/18639 0.0476190476190476 4.10912698412698 0.217228133790402 0.444838494563433 GO:0001846 opsonin binding 1/216 21/18639 0.0476190476190476 4.10912698412698 0.217228133790402 0.444838494563433 GO:0015125 bile acid transmembrane transporter activity 1/216 21/18639 0.0476190476190476 4.10912698412698 0.217228133790402 0.444838494563433 GO:0051428 peptide hormone receptor binding 1/216 21/18639 0.0476190476190476 4.10912698412698 0.217228133790402 0.444838494563433 GO:0070182 DNA polymerase binding 1/216 21/18639 0.0476190476190476 4.10912698412698 0.217228133790402 0.444838494563433 GO:0015377 chloride:monoatomic cation symporter activity 1/216 22/18639 0.0454545454545455 3.92234848484848 0.22630959920566 0.4583798063911 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/216 22/18639 0.0454545454545455 3.92234848484848 0.22630959920566 0.4583798063911 GO:0033691 sialic acid binding 1/216 22/18639 0.0454545454545455 3.92234848484848 0.22630959920566 0.4583798063911 GO:0020037 heme binding 3/216 142/18639 0.0211267605633803 1.82306338028169 0.227571414088887 0.459265498722862 GO:0031267 small GTPase binding 5/216 283/18639 0.0176678445229682 1.52458775029446 0.231901369358751 0.460028712171847 GO:0004602 glutathione peroxidase activity 1/216 23/18639 0.0434782608695652 3.7518115942029 0.235286186549033 0.460028712171847 GO:0005212 structural constituent of eye lens 1/216 23/18639 0.0434782608695652 3.7518115942029 0.235286186549033 0.460028712171847 GO:0005283 amino acid:sodium symporter activity 1/216 23/18639 0.0434782608695652 3.7518115942029 0.235286186549033 0.460028712171847 GO:0016917 GABA receptor activity 1/216 23/18639 0.0434782608695652 3.7518115942029 0.235286186549033 0.460028712171847 GO:0070577 lysine-acetylated histone binding 1/216 23/18639 0.0434782608695652 3.7518115942029 0.235286186549033 0.460028712171847 GO:0033192 calmodulin-dependent protein phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0140791 histone H2AXS140 phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/216 81/18639 0.0246913580246914 2.13065843621399 0.241500891254005 0.460028712171847 GO:0015295 solute:proton symporter activity 1/216 24/18639 0.0416666666666667 3.59548611111111 0.244159101445112 0.460028712171847 GO:0019957 C-C chemokine binding 1/216 24/18639 0.0416666666666667 3.59548611111111 0.244159101445112 0.460028712171847 GO:0050699 WW domain binding 1/216 24/18639 0.0416666666666667 3.59548611111111 0.244159101445112 0.460028712171847 GO:0060229 lipase activator activity 1/216 24/18639 0.0416666666666667 3.59548611111111 0.244159101445112 0.460028712171847 GO:0140033 acetylation-dependent protein binding 1/216 24/18639 0.0416666666666667 3.59548611111111 0.244159101445112 0.460028712171847 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/216 82/18639 0.024390243902439 2.10467479674797 0.245790772313188 0.460028712171847 GO:0033549 MAP kinase phosphatase activity 2/216 82/18639 0.024390243902439 2.10467479674797 0.245790772313188 0.460028712171847 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/216 83/18639 0.0240963855421687 2.07931726907631 0.250083533048396 0.460028712171847 GO:0008135 translation factor activity, RNA binding 2/216 83/18639 0.0240963855421687 2.07931726907631 0.250083533048396 0.460028712171847 GO:0001848 complement binding 1/216 25/18639 0.04 3.45166666666667 0.252929535723267 0.460028712171847 GO:0008139 nuclear localization sequence binding 1/216 25/18639 0.04 3.45166666666667 0.252929535723267 0.460028712171847 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/216 25/18639 0.04 3.45166666666667 0.252929535723267 0.460028712171847 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/216 25/18639 0.04 3.45166666666667 0.252929535723267 0.460028712171847 GO:0019707 protein-cysteine S-acyltransferase activity 1/216 25/18639 0.04 3.45166666666667 0.252929535723267 0.460028712171847 GO:0120020 cholesterol transfer activity 1/216 25/18639 0.04 3.45166666666667 0.252929535723267 0.460028712171847 GO:0017018 myosin phosphatase activity 2/216 84/18639 0.0238095238095238 2.05456349206349 0.254378533840088 0.460028712171847 GO:0051117 ATPase binding 2/216 84/18639 0.0238095238095238 2.05456349206349 0.254378533840088 0.460028712171847 GO:0180051 translation factor activity 2/216 84/18639 0.0238095238095238 2.05456349206349 0.254378533840088 0.460028712171847 GO:0046906 tetrapyrrole binding 3/216 152/18639 0.0197368421052632 1.703125 0.258432764200195 0.464046044073707 GO:0008143 poly(A) binding 1/216 26/18639 0.0384615384615385 3.31891025641026 0.261598667574765 0.464046044073707 GO:0030247 polysaccharide binding 1/216 26/18639 0.0384615384615385 3.31891025641026 0.261598667574765 0.464046044073707 GO:0030507 spectrin binding 1/216 26/18639 0.0384615384615385 3.31891025641026 0.261598667574765 0.464046044073707 GO:0050681 nuclear androgen receptor binding 1/216 26/18639 0.0384615384615385 3.31891025641026 0.261598667574765 0.464046044073707 GO:0051139 metal cation:proton antiporter activity 1/216 26/18639 0.0384615384615385 3.31891025641026 0.261598667574765 0.464046044073707 GO:0001671 ATPase activator activity 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0004364 glutathione transferase activity 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0008320 protein transmembrane transporter activity 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0008395 steroid hydroxylase activity 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0015252 proton channel activity 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0035255 ionotropic glutamate receptor binding 1/216 27/18639 0.037037037037037 3.19598765432099 0.270167661708104 0.467339712954702 GO:0004197 cysteine-type endopeptidase activity 2/216 88/18639 0.0227272727272727 1.96117424242424 0.271568640731547 0.468308770549448 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/216 89/18639 0.0224719101123595 1.93913857677903 0.275865739712631 0.468885745960559 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/216 89/18639 0.0224719101123595 1.93913857677903 0.275865739712631 0.468885745960559 GO:0019789 SUMO transferase activity 1/216 28/18639 0.0357142857142857 3.08184523809524 0.278637669502594 0.468885745960559 GO:0046625 sphingolipid binding 1/216 28/18639 0.0357142857142857 3.08184523809524 0.278637669502594 0.468885745960559 GO:0050698 proteoglycan sulfotransferase activity 1/216 28/18639 0.0357142857142857 3.08184523809524 0.278637669502594 0.468885745960559 GO:0051019 mitogen-activated protein kinase binding 1/216 28/18639 0.0357142857142857 3.08184523809524 0.278637669502594 0.468885745960559 GO:0051393 alpha-actinin binding 1/216 28/18639 0.0357142857142857 3.08184523809524 0.278637669502594 0.468885745960559 GO:0097718 disordered domain specific binding 1/216 28/18639 0.0357142857142857 3.08184523809524 0.278637669502594 0.468885745960559 GO:0140793 histone H2AXY142 phosphatase activity 2/216 90/18639 0.0222222222222222 1.91759259259259 0.280161533032668 0.470030041865048 GO:0003785 actin monomer binding 1/216 29/18639 0.0344827586206897 2.97557471264368 0.287009829160186 0.475787127506618 GO:0016417 S-acyltransferase activity 1/216 29/18639 0.0344827586206897 2.97557471264368 0.287009829160186 0.475787127506618 GO:0035250 UDP-galactosyltransferase activity 1/216 29/18639 0.0344827586206897 2.97557471264368 0.287009829160186 0.475787127506618 GO:0051861 glycolipid binding 1/216 29/18639 0.0344827586206897 2.97557471264368 0.287009829160186 0.475787127506618 GO:0043178 alcohol binding 2/216 92/18639 0.0217391304347826 1.87590579710145 0.288747037488 0.477246587183431 GO:0001968 fibronectin binding 1/216 30/18639 0.0333333333333333 2.87638888888889 0.295285265855586 0.48660915112888 GO:0015103 inorganic anion transmembrane transporter activity 3/216 165/18639 0.0181818181818182 1.56893939393939 0.299288446845332 0.488826976320673 GO:0051020 GTPase binding 5/216 315/18639 0.0158730158730159 1.36970899470899 0.302229569277995 0.488826976320673 GO:0005164 tumor necrosis factor receptor binding 1/216 31/18639 0.032258064516129 2.78360215053763 0.303465091884669 0.488826976320673 GO:0005184 neuropeptide hormone activity 1/216 31/18639 0.032258064516129 2.78360215053763 0.303465091884669 0.488826976320673 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/216 31/18639 0.032258064516129 2.78360215053763 0.303465091884669 0.488826976320673 GO:0005452 solute:inorganic anion antiporter activity 1/216 31/18639 0.032258064516129 2.78360215053763 0.303465091884669 0.488826976320673 GO:0072349 modified amino acid transmembrane transporter activity 1/216 31/18639 0.032258064516129 2.78360215053763 0.303465091884669 0.488826976320673 GO:0005539 glycosaminoglycan binding 4/216 242/18639 0.0165289256198347 1.4263085399449 0.308486794133976 0.488826976320673 GO:0008378 galactosyltransferase activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0015106 bicarbonate transmembrane transporter activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0022884 macromolecule transmembrane transporter activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0042910 xenobiotic transmembrane transporter activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0051059 NF-kappaB binding 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0070717 poly-purine tract binding 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0120015 sterol transfer activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0140142 nucleocytoplasmic carrier activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0160041 neuropeptide activity 1/216 32/18639 0.03125 2.69661458333333 0.311550406811201 0.488826976320673 GO:0004725 protein tyrosine phosphatase activity 2/216 98/18639 0.0204081632653061 1.76105442176871 0.314418147462861 0.491940753193296 GO:0019001 guanyl nucleotide binding 6/216 400/18639 0.015 1.294375 0.319272735793853 0.493033406564636 GO:0032561 guanyl ribonucleotide binding 6/216 400/18639 0.015 1.294375 0.319272735793853 0.493033406564636 GO:0019956 chemokine binding 1/216 33/18639 0.0303030303030303 2.61489898989899 0.319542297611909 0.493033406564636 GO:0042923 neuropeptide binding 1/216 33/18639 0.0303030303030303 2.61489898989899 0.319542297611909 0.493033406564636 GO:0140416 transcription regulator inhibitor activity 1/216 33/18639 0.0303030303030303 2.61489898989899 0.319542297611909 0.493033406564636 GO:0140104 molecular carrier activity 4/216 249/18639 0.0160642570281124 1.38621151271754 0.326801589236876 0.500223101624666 GO:0019825 oxygen binding 1/216 34/18639 0.0294117647058824 2.53799019607843 0.327441838819898 0.500223101624666 GO:0030332 cyclin binding 1/216 34/18639 0.0294117647058824 2.53799019607843 0.327441838819898 0.500223101624666 GO:0003823 antigen binding 3/216 174/18639 0.0172413793103448 1.48778735632184 0.327794312554763 0.500223101624666 GO:0005343 organic acid:sodium symporter activity 1/216 35/18639 0.0285714285714286 2.46547619047619 0.335250092666439 0.508067119245177 GO:0004722 protein serine/threonine phosphatase activity 2/216 103/18639 0.0194174757281553 1.67556634304207 0.335656963357747 0.508067119245177 GO:0043021 ribonucleoprotein complex binding 3/216 177/18639 0.0169491525423729 1.46257062146893 0.337301823829575 0.508067119245177 GO:0030695 GTPase regulator activity 7/216 489/18639 0.0143149284253579 1.23525903203817 0.339291951893776 0.508067119245177 GO:0005319 lipid transporter activity 3/216 178/18639 0.0168539325842697 1.45435393258427 0.340469747817575 0.508067119245177 GO:0060589 nucleoside-triphosphatase regulator activity 7/216 490/18639 0.0142857142857143 1.2327380952381 0.341169541539699 0.508067119245177 GO:0005484 SNAP receptor activity 1/216 36/18639 0.0277777777777778 2.39699074074074 0.342968109221161 0.508067119245177 GO:0016409 palmitoyltransferase activity 1/216 36/18639 0.0277777777777778 2.39699074074074 0.342968109221161 0.508067119245177 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/216 36/18639 0.0277777777777778 2.39699074074074 0.342968109221161 0.508067119245177 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/216 36/18639 0.0277777777777778 2.39699074074074 0.342968109221161 0.508067119245177 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/216 36/18639 0.0277777777777778 2.39699074074074 0.342968109221161 0.508067119245177 GO:0004497 monooxygenase activity 2/216 106/18639 0.0188679245283019 1.62814465408805 0.348309352905816 0.514610900712307 GO:0042805 actinin binding 1/216 37/18639 0.027027027027027 2.33220720720721 0.350596926530639 0.51662033882954 GO:0016887 ATP hydrolysis activity 6/216 417/18639 0.0143884892086331 1.2416067146283 0.354127806748589 0.520446407279588 GO:0005496 steroid binding 2/216 108/18639 0.0185185185185185 1.59799382716049 0.356700013889261 0.520842367913236 GO:0000146 microfilament motor activity 1/216 38/18639 0.0263157894736842 2.27083333333333 0.358137570755421 0.520842367913236 GO:0005501 retinoid binding 1/216 38/18639 0.0263157894736842 2.27083333333333 0.358137570755421 0.520842367913236 GO:0019840 isoprenoid binding 1/216 38/18639 0.0263157894736842 2.27083333333333 0.358137570755421 0.520842367913236 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/216 39/18639 0.0256410256410256 2.21260683760684 0.36559105630549 0.530297443651452 GO:0140597 protein carrier chaperone 3/216 188/18639 0.0159574468085106 1.37699468085106 0.372063161853799 0.537371886457732 GO:0071949 FAD binding 1/216 40/18639 0.025 2.15729166666667 0.3729583859742 0.537371886457732 GO:0043022 ribosome binding 2/216 112/18639 0.0178571428571429 1.54092261904762 0.373362513571171 0.537371886457732 GO:0001530 lipopolysaccharide binding 1/216 41/18639 0.024390243902439 2.10467479674797 0.380240551070687 0.541672600885864 GO:0042169 SH2 domain binding 1/216 41/18639 0.024390243902439 2.10467479674797 0.380240551070687 0.541672600885864 GO:0140318 protein transporter activity 1/216 41/18639 0.024390243902439 2.10467479674797 0.380240551070687 0.541672600885864 GO:0140828 metal cation:monoatomic cation antiporter activity 1/216 41/18639 0.024390243902439 2.10467479674797 0.380240551070687 0.541672600885864 GO:0016859 cis-trans isomerase activity 1/216 42/18639 0.0238095238095238 2.05456349206349 0.387438531550778 0.547724015415694 GO:0019894 kinesin binding 1/216 42/18639 0.0238095238095238 2.05456349206349 0.387438531550778 0.547724015415694 GO:0031492 nucleosomal DNA binding 1/216 42/18639 0.0238095238095238 2.05456349206349 0.387438531550778 0.547724015415694 GO:0015294 solute:monoatomic cation symporter activity 2/216 116/18639 0.0172413793103448 1.48778735632184 0.389849508547565 0.549737155091124 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/216 43/18639 0.0232558139534884 2.00678294573643 0.394553296146414 0.553567219026581 GO:0008375 acetylglucosaminyltransferase activity 1/216 43/18639 0.0232558139534884 2.00678294573643 0.394553296146414 0.553567219026581 GO:0046915 transition metal ion transmembrane transporter activity 1/216 45/18639 0.0222222222222222 1.91759259259259 0.408536997258939 0.571746501189018 GO:0015108 chloride transmembrane transporter activity 2/216 121/18639 0.0165289256198347 1.4263085399449 0.410183335913867 0.572611824822115 GO:0004180 carboxypeptidase activity 1/216 46/18639 0.0217391304347826 1.87590579710145 0.415407816264644 0.578455384148516 GO:0001784 phosphotyrosine residue binding 1/216 47/18639 0.0212765957446809 1.83599290780142 0.422199184612239 0.583535845729571 GO:0043495 protein-membrane adaptor activity 1/216 47/18639 0.0212765957446809 1.83599290780142 0.422199184612239 0.583535845729571 GO:0140359 ABC-type transporter activity 1/216 47/18639 0.0212765957446809 1.83599290780142 0.422199184612239 0.583535845729571 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/216 48/18639 0.0208333333333333 1.79774305555556 0.428912016804782 0.588433481182915 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/216 48/18639 0.0208333333333333 1.79774305555556 0.428912016804782 0.588433481182915 GO:0140693 molecular condensate scaffold activity 1/216 48/18639 0.0208333333333333 1.79774305555556 0.428912016804782 0.588433481182915 GO:0016763 pentosyltransferase activity 1/216 49/18639 0.0204081632653061 1.76105442176871 0.435547216867724 0.59315354473184 GO:0035254 glutamate receptor binding 1/216 49/18639 0.0204081632653061 1.76105442176871 0.435547216867724 0.59315354473184 GO:0060590 ATPase regulator activity 1/216 49/18639 0.0204081632653061 1.76105442176871 0.435547216867724 0.59315354473184 GO:0005006 epidermal growth factor receptor activity 1/216 50/18639 0.02 1.72583333333333 0.442105678468401 0.599155384201701 GO:0032813 tumor necrosis factor receptor superfamily binding 1/216 50/18639 0.02 1.72583333333333 0.442105678468401 0.599155384201701 GO:0005525 GTP binding 5/216 378/18639 0.0132275132275132 1.1414241622575 0.446225557803128 0.602081144009699 GO:0003743 translation initiation factor activity 1/216 51/18639 0.0196078431372549 1.69199346405229 0.448588285034156 0.602081144009699 GO:0005048 signal sequence binding 1/216 51/18639 0.0196078431372549 1.69199346405229 0.448588285034156 0.602081144009699 GO:0030544 Hsp70 protein binding 1/216 51/18639 0.0196078431372549 1.69199346405229 0.448588285034156 0.602081144009699 GO:0004864 protein phosphatase inhibitor activity 1/216 53/18639 0.0188679245283019 1.62814465408805 0.461329416269753 0.611252691365498 GO:0005246 calcium channel regulator activity 1/216 53/18639 0.0188679245283019 1.62814465408805 0.461329416269753 0.611252691365498 GO:0008146 sulfotransferase activity 1/216 53/18639 0.0188679245283019 1.62814465408805 0.461329416269753 0.611252691365498 GO:0140296 general transcription initiation factor binding 1/216 53/18639 0.0188679245283019 1.62814465408805 0.461329416269753 0.611252691365498 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/216 53/18639 0.0188679245283019 1.62814465408805 0.461329416269753 0.611252691365498 GO:0015631 tubulin binding 5/216 385/18639 0.012987012987013 1.120670995671 0.462006073725089 0.611252691365498 GO:0003925 G protein activity 1/216 54/18639 0.0185185185185185 1.59799382716049 0.467589657638834 0.61331446862778 GO:0050661 NADP binding 1/216 54/18639 0.0185185185185185 1.59799382716049 0.467589657638834 0.61331446862778 GO:0140463 chromatin-protein adaptor activity 1/216 54/18639 0.0185185185185185 1.59799382716049 0.467589657638834 0.61331446862778 GO:0019838 growth factor binding 2/216 136/18639 0.0147058823529412 1.26899509803922 0.469069952666848 0.61331446862778 GO:0140789 histone phosphatase activity 2/216 136/18639 0.0147058823529412 1.26899509803922 0.469069952666848 0.61331446862778 GO:0019212 phosphatase inhibitor activity 1/216 56/18639 0.0178571428571429 1.54092261904762 0.47989371010164 0.624534571323863 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/216 56/18639 0.0178571428571429 1.54092261904762 0.47989371010164 0.624534571323863 GO:0045309 protein phosphorylated amino acid binding 1/216 59/18639 0.0169491525423729 1.46257062146893 0.497821079672159 0.64485195669161 GO:0070888 E-box binding 1/216 59/18639 0.0169491525423729 1.46257062146893 0.497821079672159 0.64485195669161 GO:0005085 guanyl-nucleotide exchange factor activity 3/216 230/18639 0.0130434782608696 1.12554347826087 0.499824719406167 0.645945171019107 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/216 60/18639 0.0166666666666667 1.43819444444444 0.503659112330437 0.649393809185309 GO:0015293 symporter activity 2/216 146/18639 0.0136986301369863 1.18207762557078 0.506341685994679 0.651344847803779 GO:0019905 syntaxin binding 1/216 61/18639 0.0163934426229508 1.4146174863388 0.509429586076959 0.653807095495083 GO:0019209 kinase activator activity 2/216 148/18639 0.0135135135135135 1.1661036036036 0.513591028578334 0.657632650386511 GO:0008509 monoatomic anion transmembrane transporter activity 2/216 149/18639 0.0134228187919463 1.1582774049217 0.517189440670258 0.659474886609555 GO:0005543 phospholipid binding 6/216 497/18639 0.0120724346076459 1.04175050301811 0.517397711756509 0.659474886609555 GO:0005507 copper ion binding 1/216 63/18639 0.0158730158730159 1.36970899470899 0.520770960756605 0.662258961510111 GO:0003774 cytoskeletal motor activity 2/216 153/18639 0.0130718954248366 1.12799564270153 0.531406192325511 0.671748723074135 GO:0019843 rRNA binding 1/216 65/18639 0.0153846153846154 1.3275641025641 0.531851322936613 0.671748723074135 GO:0120013 lipid transfer activity 1/216 65/18639 0.0153846153846154 1.3275641025641 0.531851322936613 0.671748723074135 GO:0003777 microtubule motor activity 1/216 68/18639 0.0147058823529412 1.26899509803922 0.54799551097222 0.689014671809315 GO:0030145 manganese ion binding 1/216 68/18639 0.0147058823529412 1.26899509803922 0.54799551097222 0.689014671809315 GO:0098960 postsynaptic neurotransmitter receptor activity 1/216 69/18639 0.0144927536231884 1.2506038647343 0.553252792197248 0.694058119941142 GO:0016782 transferase activity, transferring sulphur-containing groups 1/216 70/18639 0.0142857142857143 1.2327380952381 0.558449205599801 0.699002713526042 GO:0031491 nucleosome binding 1/216 74/18639 0.0135135135135135 1.1661036036036 0.578640090358933 0.721345533288091 GO:0016874 ligase activity 2/216 167/18639 0.0119760479041916 1.03343313373253 0.578889503374823 0.721345533288091 GO:0019003 GDP binding 1/216 75/18639 0.0133333333333333 1.15055555555556 0.583542527228444 0.725520508183579 GO:0003730 mRNA 3'-UTR binding 3/216 262/18639 0.0114503816793893 0.98807251908397 0.587826360502988 0.7292188926507 GO:0008201 heparin binding 2/216 172/18639 0.0116279069767442 1.00339147286822 0.594976534623753 0.736448732856512 GO:0019199 transmembrane receptor protein kinase activity 1/216 78/18639 0.0128205128205128 1.10630341880342 0.59791178146215 0.738278030597785 GO:0016757 glycosyltransferase activity 3/216 267/18639 0.0112359550561798 0.969569288389513 0.600658726849866 0.738278030597785 GO:0015370 solute:sodium symporter activity 1/216 79/18639 0.0126582278481013 1.09229957805907 0.602591004305972 0.738278030597785 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/216 268/18639 0.0111940298507463 0.965951492537313 0.603193755490646 0.738278030597785 GO:0003735 structural constituent of ribosome 2/216 175/18639 0.0114285714285714 0.986190476190476 0.604407148927451 0.738278030597785 GO:0004721 phosphoprotein phosphatase activity 2/216 175/18639 0.0114285714285714 0.986190476190476 0.604407148927451 0.738278030597785 GO:0000049 tRNA binding 1/216 80/18639 0.0125 1.07864583333333 0.607216022790342 0.740086049659126 GO:0001618 virus receptor activity 1/216 81/18639 0.0123456790123457 1.065329218107 0.611787461934546 0.744029729907298 GO:0140272 exogenous protein binding 1/216 82/18639 0.0121951219512195 1.05233739837398 0.616305939584193 0.747891957186047 GO:1901681 sulfur compound binding 3/216 275/18639 0.0109090909090909 0.941363636363636 0.620642002597186 0.749594354304645 GO:0030165 PDZ domain binding 1/216 83/18639 0.0120481927710843 1.03965863453815 0.620772066493166 0.749594354304645 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/216 181/18639 0.0110497237569061 0.953499079189687 0.622770019308127 0.749594354304645 GO:0008017 microtubule binding 3/216 276/18639 0.0108695652173913 0.937952898550725 0.623091895948026 0.749594354304645 GO:0001217 DNA-binding transcription repressor activity 3/216 278/18639 0.0107913669064748 0.931205035971223 0.627959437266293 0.753821996890787 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/216 86/18639 0.0116279069767442 1.00339147286822 0.633862345634062 0.756952097541733 GO:0050660 flavin adenine dinucleotide binding 1/216 86/18639 0.0116279069767442 1.00339147286822 0.633862345634062 0.756952097541733 GO:1901981 phosphatidylinositol phosphate binding 2/216 185/18639 0.0108108108108108 0.932882882882883 0.634643859159766 0.756952097541733 GO:0008081 phosphoric diester hydrolase activity 1/216 87/18639 0.0114942528735632 0.991858237547893 0.638125038101212 0.759477876543536 GO:0008234 cysteine-type peptidase activity 2/216 187/18639 0.0106951871657754 0.922905525846702 0.640470846482381 0.760644480790376 GO:0003727 single-stranded RNA binding 1/216 89/18639 0.0112359550561798 0.969569288389513 0.646502791278551 0.766174584557772 GO:0019902 phosphatase binding 2/216 190/18639 0.0105263157894737 0.908333333333333 0.649074533986538 0.767589204735672 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/216 91/18639 0.010989010989011 0.948260073260073 0.654687468624423 0.772586694965685 GO:0051219 phosphoprotein binding 1/216 93/18639 0.010752688172043 0.927867383512545 0.662683499592898 0.780369364214046 GO:0042562 hormone binding 1/216 94/18639 0.0106382978723404 0.917996453900709 0.666612129167357 0.783339569506789 GO:0016758 hexosyltransferase activity 2/216 197/18639 0.0101522842639594 0.876057529610829 0.668516277870766 0.783923298471614 GO:0030594 neurotransmitter receptor activity 1/216 97/18639 0.0103092783505155 0.889604810996564 0.678126836741185 0.793522369884118 GO:0042626 ATPase-coupled transmembrane transporter activity 1/216 98/18639 0.0102040816326531 0.880527210884354 0.681876410857456 0.796237234481349 GO:0003714 transcription corepressor activity 2/216 204/18639 0.00980392156862745 0.845996732026144 0.687082718254596 0.800638230267385 GO:0008238 exopeptidase activity 1/216 102/18639 0.00980392156862745 0.845996732026144 0.696444899547993 0.809853463566247 GO:0000149 SNARE binding 1/216 106/18639 0.00943396226415094 0.814072327044025 0.710349170828572 0.824301016982322 GO:1902936 phosphatidylinositol bisphosphate binding 1/216 111/18639 0.00900900900900901 0.777402402402402 0.726841253798387 0.841685194107488 GO:0004674 protein serine/threonine kinase activity 4/216 433/18639 0.0092378752886836 0.797151655119323 0.742406083491355 0.857925702291876 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/216 122/18639 0.00819672131147541 0.707308743169399 0.759906992430525 0.876331666219053 GO:0042826 histone deacetylase binding 1/216 127/18639 0.0078740157480315 0.679461942257218 0.773588899554357 0.890266564156564 GO:0035591 signaling adaptor activity 1/216 129/18639 0.00775193798449612 0.668927648578811 0.778841793897327 0.89446366845528 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/216 130/18639 0.00769230769230769 0.663782051282051 0.781422570370486 0.895581011720907 GO:0042393 histone binding 2/216 247/18639 0.00809716599190283 0.698717948717949 0.783125389894556 0.895689614314718 GO:0042578 phosphoric ester hydrolase activity 3/216 363/18639 0.00826446280991736 0.713154269972452 0.795178778613442 0.907611843622309 GO:0030295 protein kinase activator activity 1/216 139/18639 0.00719424460431655 0.620803357314149 0.80334130723384 0.913185934957651 GO:0140767 enzyme-substrate adaptor activity 1/216 139/18639 0.00719424460431655 0.620803357314149 0.80334130723384 0.913185934957651 GO:0004713 protein tyrosine kinase activity 1/216 140/18639 0.00714285714285714 0.616369047619048 0.80563743034938 0.913930852758869 GO:0019903 protein phosphatase binding 1/216 144/18639 0.00694444444444444 0.599247685185185 0.814558131179691 0.920301985937298 GO:0019955 cytokine binding 1/216 144/18639 0.00694444444444444 0.599247685185185 0.814558131179691 0.920301985937298 GO:0008194 UDP-glycosyltransferase activity 1/216 145/18639 0.00689655172413793 0.595114942528736 0.816723875633067 0.920880969084248 GO:0019842 vitamin binding 1/216 150/18639 0.00666666666666667 0.575277777777778 0.827180710449862 0.922262399051647 GO:0016791 phosphatase activity 2/216 273/18639 0.00732600732600733 0.632173382173382 0.82780459309552 0.922262399051647 GO:0000510 H3-H4 histone complex chaperone activity 1/216 151/18639 0.00662251655629139 0.571467991169978 0.829199692901202 0.922262399051647 GO:0140584 chromatin extrusion motor activity 1/216 151/18639 0.00662251655629139 0.571467991169978 0.829199692901202 0.922262399051647 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/216 151/18639 0.00662251655629139 0.571467991169978 0.829199692901202 0.922262399051647 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/216 151/18639 0.00662251655629139 0.571467991169978 0.829199692901202 0.922262399051647 GO:0015616 DNA translocase activity 1/216 152/18639 0.00657894736842105 0.567708333333333 0.831195196272759 0.922262399051647 GO:0140674 ATP-dependent histone chaperone activity 1/216 152/18639 0.00657894736842105 0.567708333333333 0.831195196272759 0.922262399051647 GO:0061775 cohesin loader activity 1/216 153/18639 0.0065359477124183 0.563997821350763 0.833167492351359 0.922612909025263 GO:0140375 immune receptor activity 1/216 156/18639 0.00641025641025641 0.553151709401709 0.838947807938909 0.927170494091215 GO:0140658 ATP-dependent chromatin remodeler activity 1/216 158/18639 0.00632911392405063 0.546149789029536 0.842690158677408 0.929167746612022 GO:0035091 phosphatidylinositol binding 2/216 284/18639 0.00704225352112676 0.60768779342723 0.844091346114333 0.929167746612022 GO:0003689 DNA clamp loader activity 1/216 160/18639 0.00625 0.539322916666667 0.846345942123277 0.929812011366204 GO:0015081 sodium ion transmembrane transporter activity 1/216 164/18639 0.00609756097560976 0.526168699186992 0.853405734878058 0.933884075298779 GO:0140713 histone chaperone activity 1/216 164/18639 0.00609756097560976 0.526168699186992 0.853405734878058 0.933884075298779 GO:0140030 modification-dependent protein binding 1/216 173/18639 0.00578034682080925 0.498795761078998 0.868131872125903 0.948136181910055 GO:0004252 serine-type endopeptidase activity 1/216 176/18639 0.00568181818181818 0.490293560606061 0.872705652829774 0.951266239972963 GO:0016853 isomerase activity 1/216 180/18639 0.00555555555555556 0.479398148148148 0.878559301459891 0.955776427564765 GO:0008236 serine-type peptidase activity 1/216 194/18639 0.00515463917525773 0.444802405498282 0.897015436887203 0.969913355778891 GO:0017171 serine hydrolase activity 1/216 198/18639 0.00505050505050505 0.435816498316498 0.901755737179026 0.969913355778891 GO:0008094 ATP-dependent activity, acting on DNA 1/216 210/18639 0.00476190476190476 0.410912698412698 0.914712457907483 0.969913355778891 GO:0106310 protein serine kinase activity 2/216 361/18639 0.00554016620498615 0.478070175438596 0.924107630201421 0.969913355778891 GO:0003712 transcription coregulator activity 3/216 495/18639 0.00606060606060606 0.522979797979798 0.928948308487782 0.969913355778891 GO:0061659 ubiquitin-like protein ligase activity 2/216 372/18639 0.00537634408602151 0.463933691756272 0.931731403482399 0.969913355778891 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/216 229/18639 0.00436681222707424 0.376819505094614 0.931836417394242 0.969913355778891 GO:0000287 magnesium ion binding 1/216 230/18639 0.00434782608695652 0.37518115942029 0.932636163936494 0.969913355778891 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/216 243/18639 0.00411522633744856 0.355109739368999 0.942221197536789 0.969913355778891 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0004711 ribosomal protein S6 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0035175 histone H3S10 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0035979 histone H2AXS139 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0044022 histone H3S28 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0044023 histone H4S1 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0044024 histone H2AS1 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0044025 histone H2BS14 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0072354 histone H3T3 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0072371 histone H2AS121 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0140823 histone H2BS36 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0140855 histone H3S57 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0140995 histone H2A kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0140997 histone H4 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0140998 histone H2B kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:1990244 histone H2AT120 kinase activity 1/216 245/18639 0.00408163265306122 0.352210884353741 0.943570108949749 0.969913355778891 GO:0004677 DNA-dependent protein kinase activity 1/216 246/18639 0.0040650406504065 0.350779132791328 0.944232762884013 0.969913355778891 GO:0140857 histone H3T45 kinase activity 1/216 246/18639 0.0040650406504065 0.350779132791328 0.944232762884013 0.969913355778891 GO:0035402 histone H3T11 kinase activity 1/216 247/18639 0.00404858299595142 0.349358974358974 0.944887670904295 0.969913355778891 GO:0035403 histone H3T6 kinase activity 1/216 247/18639 0.00404858299595142 0.349358974358974 0.944887670904295 0.969913355778891 GO:0004679 AMP-activated protein kinase activity 1/216 248/18639 0.00403225806451613 0.347950268817204 0.945534923138129 0.969913355778891 GO:0003713 transcription coactivator activity 1/216 256/18639 0.00390625 0.337076822916667 0.950447809031312 0.973160716232428 GO:0046873 metal ion transmembrane transporter activity 2/216 450/18639 0.00444444444444444 0.383518518518519 0.968330484968991 0.9891070378495 GO:0019787 ubiquitin-like protein transferase activity 2/216 479/18639 0.00417536534446764 0.360299234516353 0.976359139311184 0.9891070378495 GO:0030371 translation repressor activity 1/216 329/18639 0.00303951367781155 0.262284701114488 0.97912621349369 0.9891070378495 GO:0016755 aminoacyltransferase activity 2/216 496/18639 0.00403225806451613 0.347950268817204 0.980112726810434 0.9891070378495 GO:0140097 catalytic activity, acting on DNA 1/216 336/18639 0.00297619047619048 0.256820436507937 0.980790370816257 0.9891070378495 GO:0005261 monoatomic cation channel activity 1/216 341/18639 0.00293255131964809 0.253054740957967 0.981897546453377 0.9891070378495 GO:0061630 ubiquitin protein ligase activity 1/216 353/18639 0.0028328611898017 0.244452313503305 0.984302415805726 0.9891070378495 GO:0141003 histone H2AX kinase activity 1/216 354/18639 0.00282485875706215 0.243761770244821 0.984487840621758 0.9891070378495 GO:0045182 translation regulator activity 1/216 356/18639 0.00280898876404494 0.242392322097378 0.984852174946089 0.9891070378495 GO:0140996 histone H3 kinase activity 1/216 357/18639 0.00280112044817927 0.24171335200747 0.98503113519395 0.9891070378495 GO:0035173 histone kinase activity 1/216 360/18639 0.00277777777777778 0.239699074074074 0.98555548654663 0.9891070378495 GO:0005216 monoatomic ion channel activity 1/216 448/18639 0.00223214285714286 0.192615327380952 0.994938172550664 0.994998276708163 GO:0004842 ubiquitin-protein transferase activity 1/216 449/18639 0.0022271714922049 0.192186340014848 0.994998276708163 0.994998276708163