category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Neurodegenerative disease hsa05020 Prion disease 21/153 275/9376 4.67964349376114 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/EGR1/HSPA5/MT-ND4L/MT-ND6/HSPA8/TNF/C1QA/TUBB4B/IL6/CAV1/TUBB 7.97669125543961 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 13/153 94/9376 8.47503824224725 FOS/FOSB/JUN/S100A8/CCL2/JUND/HSP90B1/NFKBIA/TNF/IL6/HSP90AB1/S100A9/FOSL1 9.3810578234582 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 14/153 142/9376 6.04179324311884 FOS/HMOX1/DUSP1/ACTB/JUN/CCL2/ACTG1/CTSL/KLF2/HSP90B1/TNF/MGST1/HSP90AB1/CAV1 7.79703562024053 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 17/153 227/9376 4.58932941752325 FOS/MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/HMOX1/MT-ND5/JUN/MT-ND4L/MT-ND6/NFKBIA/MGST1 7.05073971317578 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 16/153 205/9376 4.78291088793241 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/MT-ND4L/MT-ND6/CAMK2D/PDK4/COL1A2/COL1A1 7.05326082482557 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 18/153 268/9376 4.11589113257243 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/DUSP1/MT-ND5/UBC/HSPA5/MT-ND4L/MT-ND6/CAMK2D/TUBB4B/TUBB 6.66551040344718 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 17/153 248/9376 4.20071684587814 FOS/ACTB/JUN/AHNAK/S100A10/ACTG1/RHOB/HSP90B1/NFKBIA/FLNA/TNF/ANXA2/TUBB4B/IL6/HSP90AB1/DYNC1I1/TUBB 6.57931272546344 Cellular Processes Transport and catabolism hsa04145 Phagosome 13/153 155/9376 5.13970061142737 ACTB/HLA-C/MARCO/OLR1/CALR/CLEC7A/ACTG1/CTSL/MSR1/ITGA5/TUBB4B/DYNC1I1/TUBB 6.69331124988268 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 12/153 138/9376 5.32878658709861 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/MT-ND4L/MT-ND6 6.59799510157877 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 15/153 235/9376 3.91155611180642 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/ACTB/ACTG1/MT-ND4L/PPARG/MT-ND6 5.82180279474662 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 14/153 216/9376 3.97191963205035 FOS/HSPA5/CCL3/JUN/OLR1/CCL2/PPARG/HSP90B1/HSPA8/NFKBIA/CAMK2D/TNF/IL6/HSP90AB1 5.69129960869617 Cellular Processes Cell growth and death hsa04210 Apoptosis 11/153 137/9376 4.92037593626258 FOS/ACTB/MCL1/JUN/ACTG1/CTSL/NFKBIA/GADD45G/TNF/CTSZ/LMNA 5.95347815057079 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 13/153 204/9376 3.90516468025119 ACTB/ACTG1/CTSL/FN1/CAMK2D/FLNA/ITGA5/TNF/CDKN1A/COL1A2/CAV1/COL1A1/CD44 5.40317539406409 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 18/153 368/9376 2.99744245524297 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/ACTB/HSPA5/ACTG1/MT-ND4L/MT-ND6/TNF/TUBB4B/TUBB 5.03476548561525 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 9/153 103/9376 5.35465448315248 FOS/CCL3/JUN/CALR/CCL2/NFKBIA/TNF/C1QA/IL6 5.7234439444628 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 11/153 157/9376 4.29357645393614 FOS/MT-CO1/MT-CO3/MT-CO2/MT-CYB/JUN/NR1H3/PPARG/TNF/IL6/SOCS3 5.36007562532103 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 10/153 138/9376 4.44065548924884 FOS/ACTB/JUN/CCL2/ACTG1/FN1/NFKBIA/ITGA5/TNF/IL6 5.24429366232622 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 13/153 233/9376 3.41911414064911 FMNL2/ACTB/VIM/ACTG1/FN1/TPM4/SNTB1/PLEC/ITGA5/VCAN/COL1A2/LMNA/COL1A1 4.81598593615399 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 15/153 308/9376 2.98446651387828 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/MT-ND4L/PPARG/MT-ND6/TUBB4B/TUBB 4.56098481967965 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 17/153 388/9376 2.68499427262314 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/APOE/MT-ND4L/MT-ND6/TNF/TUBB4B/IL6/TUBB 4.36594247523249 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 8/153 99/9376 4.95200369710174 ACTB/ACTG1/TPM4/SNTB1/ITGA5/TNF/IL6/LMNA 5.09127329834886 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 8/153 101/9376 4.85394421795121 EGR1/JUN/CCL2/FN1/TNF/IL6/COL1A2/COL1A1 5.01538643993529 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 19/153 480/9376 2.42570806100218 MT-CO1/MT-CO3/MT-CO2/MT-ND3/MT-ND2/MT-ND1/MT-ATP6/MT-ND4/MT-CYB/MT-ND5/UBC/HSPA5/MT-ND4L/MT-ND6/CAMK2D/TNF/TUBB4B/IL6/TUBB 4.12999081678382 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 12/153 224/9376 3.28291316526611 FOS/ZFP36/EGR1/HLA-C/JUN/CALR/EGR2/NFKBIA/TNF/CDKN1A/IL6/FOSL1 4.45400443726159 Organismal Systems Immune system hsa04612 Antigen processing and presentation 7/153 82/9376 5.23130878367607 HLA-C/HSPA5/CALR/CTSL/HSPA8/TNF/HSP90AB1 4.9565051406028 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 11/153 203/9376 3.32064779934963 ACTB/JUN/ACTG1/FN1/FLNB/EMP1/FLNA/ITGA5/COL1A2/CAV1/COL1A1 4.30523443061224 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 12/153 238/9376 3.08980062613281 FOS/ISG15/C5AR1/JUN/CCL2/NFKBIA/MX1/TNF/RPL35/C1QA/IL6/RPL8 4.20593935085462 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 9/153 142/9376 3.88400994200497 FOS/FOSB/JUN/PPARG/JUND/NFKBIA/TNF/SOCS3/FOSL1 4.46006552879395 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 11/153 205/9376 3.28825123545353 ISG15/HLA-C/JUN/CALR/VIM/NFKBIA/GADD45G/TNF/CDKN1A/IL6/CD44 4.26645862789657 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 7/153 95/9376 4.51544547643619 FOS/CCL3/JUN/CCL2/CTSL/TNF/IL6 4.43547394187897 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 4/153 30/9376 8.17080610021786 DHFR/ABCC3/TNF/IL6 5.06653407178524 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 7/153 105/9376 4.08540305010893 ACTB/ACTG1/TPM4/SNTB1/ITGA5/TNF/LMNA 4.09485485785675 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 6/153 78/9376 4.71392659627954 FOS/JUN/ITGA5/TNF/C1QA/IL6 4.24210189087992 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 7/153 109/9376 3.93548000239851 FOS/CCL3/JUN/CCL4/NFKBIA/TNF/IL6 3.97025172299702 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 5/153 56/9376 5.47152194211018 HSPA8/NFKBIA/TNF/EEF1A1/IL6 4.32251663018063 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 14/153 362/9376 2.36998519481457 CSH1/MCL1/CSH2/FN1/CSHL1/HSP90B1/ITGA5/CDKN1A/NR4A1/IL6/HSP90AB1/COL1A2/SGK1/COL1A1 3.42378615590523 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 7/153 115/9376 3.73015061096903 FOS/EGR1/NR4A2/JUND/MAFB/CDKN1A/SGK1 3.79403937095802 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 7/153 119/9376 3.60476739715494 FOS/JUN/CCL2/NFKBIA/TNF/IL6/SOCS3 3.68300701006735 NA NA hsa04518 Integrin signaling 8/153 154/9376 3.18343094813683 ACTB/ACTG1/FN1/FLNB/FLNA/ITGA5/COL1A2/COL1A1 3.51870219974293 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 8/153 154/9376 3.18343094813683 FOS/ACTB/JUN/ACTG1/CAMK2D/RGS2/CDKN1A/MYL6 3.51870219974293 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 8/153 157/9376 3.1226010574081 CALR/NR1H3/PPARG/STAB1/CAMK2D/C1QA/SGK1/SIGLEC10 3.4543914037571 Cellular Processes Cell growth and death hsa04216 Ferroptosis 4/153 42/9376 5.83629007158419 HMOX1/FTH1/FTL/SLC7A11 4.04574342825283 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 9/153 200/9376 2.75764705882353 FOS/ACTB/JUN/ACTG1/NFKBIA/TNF/TUBB4B/IL6/TUBB 3.23604994927269 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 5/153 70/9376 4.37721755368814 ACTB/HLA-C/ACTG1/SNTB1/CAV1 3.6527654228721 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 6/153 105/9376 3.50177404295051 JUN/CLEC7A/EGR2/NFKBIA/TNF/IL6 3.32027985539009 Human Diseases Infectious disease: viral hsa05164 Influenza A 8/153 173/9376 2.83380558389059 ACTB/CCL2/ACTG1/NFKBIA/MX1/TNF/IL6/SOCS3 3.13550054538462 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 7/153 139/9376 3.08609582921898 FOS/JUN/HSP90B1/FKBP5/HSPA8/GABBR1/HSP90AB1 3.19132792470068 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 5/153 76/9376 4.03164774681802 UBC/OLR1/NR1H3/PPARG/FABP5 3.41774226830968 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 5/153 78/9376 3.92827216356628 ACTB/ACTG1/FN1/ITGA5/CAV1 3.3447157772368 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 5/153 78/9376 3.92827216356628 FOS/JUN/NFKBIA/TNF/EEF1A1 3.3447157772368 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 8/153 180/9376 2.72360203340595 HLA-C/CALR/CCL2/NFKBIA/ITGA5/TNF/IL6/SOCS3 3.00724643223552 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 7/153 149/9376 2.87897530376804 MT-ND3/MT-ND2/MT-ND1/MT-ND4/MT-ND5/MT-ND4L/MT-ND6 2.97768803057789 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 8/153 187/9376 2.62164901611268 TXNIP/JUN/CCL2/NFKBIA/TNF/IL6/HSP90AB1/GABARAPL1 2.88495331507441 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 9/153 226/9376 2.44039562727746 FOS/JUN/CGA/NFKBIA/CAMK2D/GABBR1/CRH/SUCNR1/SST 2.82306394942638 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 9/153 227/9376 2.4296449857476 HLA-C/CCL3/CALR/CCL2/CCL4/NFKBIA/TNF/CDKN1A/IL6 2.80833924786675 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 5/153 86/9376 3.56285149718802 ACTB/ACTG1/SNTB1/ITGA5/LMNA 3.07510578229293 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 5/153 87/9376 3.52189918112839 MT-CO1/MT-CO3/MT-CO2/MT-CYB/TPM4 3.0436738623501 Cellular Processes Cell growth and death hsa04218 Cellular senescence 7/153 157/9376 2.73227592523209 HLA-C/ZFP36L1/ZFP36L2/GADD45G/CDKN1A/IL6/HIPK2 2.81916332990246 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 6/153 122/9376 3.01382192221151 FOS/CSH1/CSH2/CSHL1/SOCS3/SST 2.8835765247514 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 8/153 196/9376 2.50126717353608 FOS/ZFP36/UBC/HLA-C/JUN/NFKBIA/CDKN1A/IL6 2.73564622081895 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 5/153 89/9376 3.44275537930528 FN1/ITGA5/COL1A2/COL1A1/CD44 2.9821707635263 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 7/153 163/9376 2.63170135129717 FOS/JUN/EGR2/NFKBIA/TNF/CDKN1A/IL6 2.70663185674444 Organismal Systems Digestive system hsa04978 Mineral absorption 4/153 61/9376 4.01842922961534 HMOX1/FTH1/FTL/SLC26A3 3.04613912625935 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 7/153 168/9376 2.55337690631808 CSH1/MCL1/CSH2/CSHL1/CDKN1A/IL6/SOCS3 2.6166406210876 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 9/153 250/9376 2.20611764705882 VAMP8/PSAP/CTSL/SLC11A1/LAPTM5/SLC36A1/GAA/CTSZ/CD68 2.48951468956356 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 7/153 170/9376 2.52333717800846 HMOX1/ACTB/ACTG1/GADD45G/MGST1/CDKN1A/TXNRD1 2.58154836637405 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 6/153 133/9376 2.76455845496093 KLF2/GADD45G/CDKN1A/IL6/GABARAPL1/SGK1 2.63967611759639 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 3/153 37/9376 4.96873343932167 PPARG/GADD45G/CDKN1A 3.11528550254112 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 5/153 100/9376 3.0640522875817 CCL3/CCL2/CCL4/TNF/IL6 2.67260990833084 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 5/153 100/9376 3.0640522875817 CD9/ITGA5/TNF/IL6/CD44 2.67260990833084 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 7/153 174/9376 2.46532942678987 HSPA5/CALR/HSP90B1/HSPA8/DNAJA1/HSP90AB1/RPN1 2.51283533373097 Human Diseases Infectious disease: viral hsa05162 Measles 6/153 136/9376 2.70357554786621 FOS/JUN/HSPA8/NFKBIA/MX1/IL6 2.57744920800112 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 10/153 300/9376 2.04270152505447 FOS/DUSP1/DUSP6/JUN/JUND/HSPA8/GADD45G/FLNA/TNF/NR4A1 2.36411523538755 Human Diseases Substance dependence hsa05031 Amphetamine addiction 4/153 69/9376 3.55252439139907 FOS/FOSB/JUN/CAMK2D 2.74084728746532 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 5/153 103/9376 2.97480804619582 FN1/TNF/IL6/COL1A2/COL1A1 2.59554534055558 Organismal Systems Immune system hsa04659 Th17 cell differentiation 5/153 109/9376 2.81105714457037 FOS/JUN/NFKBIA/IL6/HSP90AB1 2.44946405453332 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 5/153 109/9376 2.81105714457037 NR1H3/NFKBIA/TNF/IL6/SOCS3 2.44946405453332 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 4/153 75/9376 3.26832244008715 HSPA5/CGA/HSP90B1/TG 2.54018792942376 Organismal Systems Digestive system hsa04971 Gastric acid secretion 4/153 76/9376 3.22531819745442 ACTB/ACTG1/CAMK2D/SST 2.50872287912122 Human Diseases Immune disease hsa05332 Graft-versus-host disease 3/153 45/9376 4.08540305010893 HLA-C/TNF/IL6 2.67207913578795 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 3/153 46/9376 3.99658994032396 HMOX1/FTH1/FTL 2.62398084573836 Cellular Processes Cell motility hsa04814 Motor proteins 7/153 194/9376 2.21117175392494 ACTB/ACTG1/TPM4/TUBB4B/MYL6/DYNC1I1/TUBB 2.19549879971727 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 6/153 156/9376 2.35696329813977 NR1H3/NFKBIA/MX1/TNF/CDKN1A/SOCS3 2.201203473073 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/153 50/9376 3.67686274509804 CCL2/TNF/IL6 2.44432331011629 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 4/153 87/9376 2.81751934490271 FOS/JUN/GADD45G/CDKN1A 2.19355958628008 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 8/153 253/9376 1.93774057712677 ACTB/UBC/JUN/ACTG1/NFKBIA/ITGA5/TNF/CD44 1.94746374464546 Organismal Systems Immune system hsa04611 Platelet activation 5/153 126/9376 2.43178752982675 ACTB/ACTG1/VAMP8/COL1A2/COL1A1 2.08395449288308 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 4/153 88/9376 2.78550207961973 C5AR1/TFPI/CLU/C1QA 2.16738389697063 Cellular Processes Cell growth and death hsa04217 Necroptosis 6/153 168/9376 2.18860877684407 GLUL/FTH1/FTL/CAMK2D/TNF/HSP90AB1 2.00219405568695 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 3/153 54/9376 3.40450254175744 HLA-C/CGA/TG 2.28224792239801 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 7/153 214/9376 2.00452018813756 FOS/HLA-C/JUN/CALR/NFKBIA/TNF/APOBEC3A 1.91454536579977 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 5/153 130/9376 2.35696329813977 FOS/JUN/NFKBIA/COL1A2/COL1A1 2.00658740683067 NA NA hsa04382 Cornified envelope formation 7/153 217/9376 1.97680792747206 S100A8/S100A10/S100A6/S100A4/S100A11/PLEC/S100A9 1.87503881418254 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 4/153 93/9376 2.63574390329609 EGR1/JUN/CGA/CAMK2D 2.04177489054949 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 4/153 93/9376 2.63574390329609 FN1/NFKBIA/GADD45G/CDKN1A 2.04177489054949 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 5/153 144/9376 2.1278140885984 C5AR1/NFKBIA/TNF/C1QA/IL6 1.75657263560126 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 4/153 103/9376 2.37984643695666 SLC36A1/SLC7A8/COL1A2/COL1A1 1.81357068957878 Organismal Systems Endocrine system hsa04929 GnRH secretion 3/153 65/9376 2.82835595776772 CGA/KISS1/GABBR1 1.90508569312095 NA NA hsa04981 Folate transport and metabolism 2/153 31/9376 3.95361585494413 DHFR/ABCC3 2.12148738656101 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 4/153 105/9376 2.33451602863368 CCL4/NFKBIA/GADD45G/TNF 1.77112985045677 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 4/153 105/9376 2.33451602863368 UBC/JUN/GABARAPL1/CITED2 1.77112985045677 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 3/153 66/9376 2.78550207961973 JUN/TNF/IL6 1.8747904687049 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 9/153 333/9376 1.65624447977389 ISG15/HLA-C/FN1/ITGA5/MX1/TNF/CDKN1A/COL1A2/COL1A1 1.57045958250317 Human Diseases Cancer: specific types hsa05215 Prostate cancer 4/153 106/9376 2.31249229251449 HSP90B1/NFKBIA/CDKN1A/HSP90AB1 1.75027011135453 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 4/153 110/9376 2.22840166369578 HMOX1/CAMK2D/CDKN1A/IL6 1.66911338514561 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 3/153 70/9376 2.62633053221289 NFKBIA/TNF/SOCS3 1.75902317212016 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 3/153 71/9376 2.58933996133665 FOS/CGA/SOCS3 1.7313426917313 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 3/153 72/9376 2.55337690631808 ISG15/NFKBIA/TNF 1.70413301747716 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 8/153 298/9376 1.64512874501031 CSH1/CCL3/CSH2/CCL2/CSHL1/CCL4/TNF/IL6 1.4576547940811 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 2/153 37/9376 3.31248895954778 TNF/IL6 1.81520463407512 Human Diseases Cancer: specific types hsa05214 Glioma 3/153 76/9376 2.41898864809082 CAMK2D/GADD45G/CDKN1A 1.59970348993276 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 3/153 77/9376 2.38757321110262 NFKBIA/GADD45G/CDKN1A 1.57462954043799 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 2/153 39/9376 3.14261773085302 DHFR/MAT2A 1.72690548104293 Human Diseases Immune disease hsa05330 Allograft rejection 2/153 39/9376 3.14261773085302 HLA-C/TNF 1.72690548104293 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 4/153 122/9376 2.00921461480767 FOS/JUN/NFKBIA/TNF 1.44508684685466 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 6/153 217/9376 1.69440679497606 FOS/KLF4/JUN/HSP90B1/MGST1/HSP90AB1 1.33295365116643 NA NA hsa04081 Hormone signaling 6/153 219/9376 1.67893276031874 CSH1/CSH2/CGA/CSHL1/CRH/SST 1.30938531121656 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 9/153 370/9376 1.4906200317965 CSH1/C5AR1/CSH2/CGA/KISS1/CSHL1/GABBR1/CRH/SST 1.24015342290775 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 3/153 83/9376 2.21497755728798 CCL4/NFKBIA/IL6 1.43193921479875 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 2/153 44/9376 2.78550207961973 HLA-C/TNF 1.52895457518215 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 3/153 86/9376 2.13771089831281 JUN/CAMK2D/CDKN1A 1.3651127916768 Organismal Systems Nervous system hsa04727 GABAergic synapse 3/153 89/9376 2.06565322758317 GLUL/GABBR1/GABARAPL1 1.30097345247062 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 2/153 47/9376 2.60770407453762 TNF/SOCS3 1.42309123620371 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 3/153 90/9376 2.04270152505447 FOS/JUN/NFKBIA 1.28015386890204 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 3/153 91/9376 2.02025425554837 FOS/JUN/NFKBIA 1.25960218792327 Human Diseases Substance dependence hsa05030 Cocaine addiction 2/153 49/9376 2.50126717353608 FOSB/JUN 1.35700138030661 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 3/153 93/9376 1.97680792747206 FOS/JUN/NFKBIA 1.21927515375928 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 2/153 51/9376 2.40317826476996 ACTB/ACTG1 1.29410276745521 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 2/153 52/9376 2.35696329813977 CGA/CYP19A1 1.26375791934204 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 3/153 98/9376 1.87595038015206 NR4A2/CAMK2D/NR4A1 1.12269194957651 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 3/153 99/9376 1.85700138641315 FOS/JUN/CDKN1A 1.10405470483063 Human Diseases Cancer: specific types hsa05224 Breast cancer 4/153 148/9376 1.65624447977389 FOS/JUN/GADD45G/CDKN1A 1.03642523161259 Metabolism Lipid metabolism hsa00600 Sphingolipid metabolism 2/153 55/9376 2.22840166369578 PSAP/SGMS2 1.17675414302371 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 5/153 201/9376 1.52440412317497 DUSP6/PPARG/GADD45G/CDKN1A/IL6 0.967957611530886 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 5/153 205/9376 1.49465965247888 HLA-C/JUN/EGR2/NFKBIA/CDKN1A 0.922295991581771 Metabolism Metabolism of other amino acids hsa00450 Selenocompound metabolism 1/153 17/9376 3.60476739715494 TXNRD1 1.38443934654632 Metabolism Energy metabolism hsa00910 Nitrogen metabolism 1/153 17/9376 3.60476739715494 GLUL 1.38443934654632 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 4/153 155/9376 1.58144634197765 CAMK2D/CRH/CDKN1A/NR4A1 0.940116618873135 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 2/153 59/9376 2.07732358480115 GADD45G/CDKN1A 1.06912719063402 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 4/153 160/9376 1.53202614379085 HLA-C/ALCAM/SIGLEC1/VCAN 0.874212438919201 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 2/153 63/9376 1.9454300238614 GADD45G/CDKN1A 0.969728394993086 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 7/153 323/9376 1.32807219895182 HMOX1/MCL1/VIM/ITGA5/CDKN1A/MARCKS/CD44 0.772804566790146 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 3/153 112/9376 1.64145658263305 HSPA8/NFKBIA/TNF 0.879573737572304 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 4/153 169/9376 1.4504389527014 UBC/VAMP8/CTSL/GABARAPL1 0.761053995035063 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 4/153 170/9376 1.44190695886198 ACTB/JUN/ACTG1/MYL6 0.74888488524313 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 3/153 120/9376 1.53202614379085 JUN/NFKBIA/CAMK2D 0.755452518571966 Metabolism Amino acid metabolism hsa00220 Arginine biosynthesis 1/153 23/9376 2.6643932935493 GLUL 1.02929451226337 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 2/153 70/9376 1.75088702147526 JUN/CDKN1A 0.812152046744191 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 2/153 71/9376 1.7262266408911 JUN/NFKBIA 0.791112800177714 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 2/153 73/9376 1.67893276031874 MX1/APOBEC3A 0.750018427575983 Human Diseases Cancer: specific types hsa05218 Melanoma 2/153 73/9376 1.67893276031874 GADD45G/CDKN1A 0.750018427575983 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 2/153 73/9376 1.67893276031874 GADD45G/CDKN1A 0.750018427575983 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 4/153 181/9376 1.35427725417976 CLEC7A/CAMK2D/TNF/IL6 0.619871886555045 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 2/153 75/9376 1.63416122004357 GLUL/MAT2A 0.710167411825913 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 2/153 75/9376 1.63416122004357 MGST1/CDKN1A 0.710167411825913 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 2/153 75/9376 1.63416122004357 GADD45G/CDKN1A 0.710167411825913 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 2/153 77/9376 1.59171547406842 GADD45G/CDKN1A 0.671483607169099 NA NA hsa04517 IgSF CAM signaling 6/153 299/9376 1.22971998163814 ACTB/ACTG1/ITGA5/TUBB4B/MYL6/TUBB 0.519946247996136 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 2/153 78/9376 1.57130886542651 BTG2/BTG1 0.652557436307461 Metabolism Glycan biosynthesis and metabolism hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1/153 28/9376 2.18860877684407 B3GNT5 0.811248386286945 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/153 28/9376 2.18860877684407 DHFR 0.811248386286945 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 4/153 193/9376 1.2700734870805 CCL3/CCL2/CCL4/NFKBIA 0.488273959857318 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 2/153 82/9376 1.49465965247888 UPP1/MGST1 0.579438475352842 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 4/153 195/9376 1.25704709234121 ACTB/C5AR1/CLEC7A/ACTG1 0.467175712764855 Metabolism Carbohydrate metabolism hsa00630 Glyoxylate and dicarboxylate metabolism 1/153 31/9376 1.97680792747206 GLUL 0.701609755295679 Genetic Information Processing Folding, sorting and degradation hsa03060 Protein export 1/153 31/9376 1.97680792747206 HSPA5 0.701609755295679 Metabolism Carbohydrate metabolism hsa00052 Galactose metabolism 1/153 32/9376 1.91503267973856 GAA 0.667790795143617 Cellular Processes Transport and catabolism hsa04136 Autophagy - other 1/153 32/9376 1.91503267973856 GABARAPL1 0.667790795143617 Human Diseases Immune disease hsa05310 Asthma 1/153 32/9376 1.91503267973856 TNF 0.667790795143617 Genetic Information Processing Folding, sorting and degradation hsa04130 SNARE interactions in vesicular transport 1/153 33/9376 1.85700138641315 VAMP8 0.635170865473123 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 2/153 89/9376 1.37710215172211 TUBB4B/TUBB 0.460374796942775 Metabolism Carbohydrate metabolism hsa00500 Starch and sucrose metabolism 1/153 36/9376 1.70225127087872 GAA 0.543707840030656 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 2/153 93/9376 1.31787195164804 ACTB/ACTG1 0.39677541696908 Metabolism Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism 1/153 37/9376 1.65624447977389 GLUL 0.515123765609127 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 1/153 38/9376 1.61265909872721 SGK1 0.487392677901939 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 2/153 97/9376 1.26352671652854 FOS/CAMK2D 0.336012303520926 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 2/153 99/9376 1.23800092427543 C5AR1/C1QA 0.306610986126988 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 2/153 99/9376 1.23800092427543 FOS/JUN 0.306610986126988 NA NA hsa04519 Cadherin signaling 7/153 404/9376 1.06180029767683 ACTB/VIM/ACTG1/CDH23/LHFPL2/NFKBIA/FMN1 0.163542964705101 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/153 41/9376 1.49465965247888 CDKN1A 0.408824114313169 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/153 44/9376 1.39275103980986 RPN1 0.336319126188154 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 1/153 44/9376 1.39275103980986 DYNC1I1 0.336319126188154 Environmental Information Processing Membrane transport hsa02010 ABC transporters 1/153 45/9376 1.36180101670298 ABCC3 0.313333762992411 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 4/153 232/9376 1.05656975433852 ACTB/ACTG1/FN1/ITGA5 0.112371305343427 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 2/153 110/9376 1.11420083184789 EMP3/TNF 0.155172483614679 NA NA hsa03272 Virion - Hepatitis viruses 1/153 48/9376 1.27668845315904 CD9 0.247521332703717 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 3/153 178/9376 1.03282661379158 JUN/CAMK2D/FOSL1 0.056948807375367 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/153 50/9376 1.22562091503268 IL6 0.206021195100143 Organismal Systems Nervous system hsa04725 Cholinergic synapse 2/153 115/9376 1.06575731741972 FOS/CAMK2D 0.0913817172637431 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 2/153 116/9376 1.05656975433852 ACTB/ACTG1 0.0789592552401997 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 2/153 117/9376 1.04753924361768 ACTB/ACTG1 0.0666435933376211 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/153 52/9376 1.17848164906988 APOE 0.16622232729397 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 1/153 54/9376 1.13483418058581 MAT2A 0.127978666342061 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/153 122/9376 1.00460730740384 ACTB/ACTG1 0.00659716895793081 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 1/153 56/9376 1.09430438842204 RPN1 0.0911618667045822 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 2/153 125/9376 0.980496732026144 TNF/SGMS2 -0.0282724407954968 Metabolism Nucleotide metabolism hsa00240 Pyrimidine metabolism 1/153 59/9376 1.03866179240058 UPP1 0.0383676493091283 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 1/153 59/9376 1.03866179240058 MGST1 0.0383676493091283 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/153 59/9376 1.03866179240058 CGA 0.0383676493091283 Organismal Systems Nervous system hsa04730 Long-term depression 1/153 60/9376 1.02135076252723 CRH 0.0213682779759204 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 1/153 62/9376 0.988403963736032 HSPA8 -0.0117986560814867 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 2/153 133/9376 0.921519484986977 HLA-C/TNF -0.117402254708036 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 2/153 133/9376 0.921519484986977 FOS/CAMK2D -0.117402254708036 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 1/153 65/9376 0.942785319255907 NR4A1 -0.059615781740407 Metabolism Lipid metabolism hsa00140 Steroid hormone biosynthesis 1/153 66/9376 0.928500693206576 CYP19A1 -0.0750748041267299 Organismal Systems Nervous system hsa04720 Long-term potentiation 1/153 67/9376 0.914642473904985 CAMK2D -0.0903073201743677 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 2/153 140/9376 0.875443510737628 EGR1/KLF2 -0.191242170361251 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/153 68/9376 0.901191849288735 DUSP6 -0.105320833998177 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 2/153 142/9376 0.863113320445549 UBC/SOCS3 -0.211692599231275 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 1/153 69/9376 0.888131097849768 TNF -0.120122486603204 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 2/153 143/9376 0.857077562959916 TNF/C1QA -0.221815690379242 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/153 70/9376 0.875443510737628 MGST1 -0.134719078631777 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/153 73/9376 0.83946638015937 MGST1 -0.177341822582584 Human Diseases Cancer: specific types hsa05226 Gastric cancer 2/153 150/9376 0.817080610021787 GADD45G/CDKN1A -0.290866629243628 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 2/153 154/9376 0.795857737034208 DHFR/MAT2A -0.328984908073776 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 2/153 154/9376 0.795857737034208 TPM4/CAMK2D -0.328984908073776 Metabolism Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450 1/153 79/9376 0.775709439894101 MGST1 -0.257838861540266 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 2/153 157/9376 0.780650264352025 ACTB/ACTG1 -0.356977039370745 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/153 80/9376 0.766013071895425 IL6 -0.270697210901546 Cellular Processes Cell growth and death hsa04110 Cell cycle 2/153 158/9376 0.775709439894101 GADD45G/CDKN1A -0.366198394858048 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 2/153 158/9376 0.775709439894101 TNF/SGK1 -0.366198394858048 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/153 85/9376 0.720953479430988 UPP1 -0.332851174525843 Organismal Systems Sensory system hsa04742 Taste transduction 1/153 86/9376 0.712570299437604 GABBR1 -0.344880198939324 Organismal Systems Endocrine system hsa04911 Insulin secretion 1/153 86/9376 0.712570299437604 CAMK2D -0.344880198939324 Organismal Systems Aging hsa04211 Longevity regulating pathway 1/153 90/9376 0.680900508351489 PPARG -0.391767384033679 Organismal Systems Digestive system hsa04976 Bile secretion 1/153 90/9376 0.680900508351489 ABCC3 -0.391767384033679 Human Diseases Substance dependence hsa05032 Morphine addiction 1/153 91/9376 0.673418085182791 GABBR1 -0.40319684255453 Cellular Processes Transport and catabolism hsa04144 Endocytosis 3/153 250/9376 0.735372549019608 HLA-C/HSPA8/CAV1 -0.546210337013099 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/153 98/9376 0.62531679338402 MARCKS -0.480225626063713 Organismal Systems Sensory system hsa04750 Inflammatory mediator regulation of TRP channels 1/153 99/9376 0.619000462137717 CAMK2D -0.490832732576657 Organismal Systems Endocrine system hsa04916 Melanogenesis 1/153 101/9376 0.606743027243901 CAMK2D -0.511770689203035 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/153 102/9376 0.60079456619249 SLC26A3 -0.522105458236583 Metabolism Lipid metabolism hsa00564 Glycerophospholipid metabolism 1/153 104/9376 0.589240824534942 SGMS2 -0.542515912372532 Human Diseases Substance dependence hsa05034 Alcoholism 2/153 191/9376 0.641686342949047 FOSB/CRH -0.644370595554491 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 1/153 107/9376 0.572720053753589 CAMK2D -0.57251017203546 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/153 108/9376 0.567417090292907 EEF1A1 -0.58234918498997 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/153 110/9376 0.557100415923945 HSP90AB1 -0.601797967150788 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/153 115/9376 0.532878658709861 DUSP1 -0.649149813475112 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/153 116/9376 0.528284877169259 GLUL -0.65841323194318 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 2/153 212/9376 0.578123073128623 ACTB/ACTG1 -0.80021449386501 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/153 122/9376 0.502303653701918 PPARG -0.712647669990436 Genetic Information Processing Translation hsa03010 Ribosome 2/153 222/9376 0.552081493257964 RPL35/RPL8 -0.869891904390032 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/153 134/9376 0.457321236952492 MYL6 -0.814905957515989 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/153 138/9376 0.444065548924884 CAMK2D -0.847362814310287 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/153 138/9376 0.444065548924884 SOCS3 -0.847362814310287 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/153 144/9376 0.42556281771968 KLF4 -0.894687028178105 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/153 166/9376 0.369162926214663 RGS2 -1.05617695374209 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/153 184/9376 0.333049161693663 CAMK2D -1.17677375972632 NA NA hsa04082 Neuroactive ligand signaling 1/153 199/9376 0.307944953525799 GABBR1 -1.2709019952439 Genetic Information Processing Transcription hsa03040 Spliceosome 1/153 243/9376 0.252185373463514 HSPA8 -1.52119753344112 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/153 254/9376 0.241263959652102 CAMK2D -1.57891149810354 Organismal Systems Sensory system hsa04740 Olfactory transduction 2/153 449/9376 0.272966796221087 CAMK2D/RGS2 -2.0333863228928