ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 11/220 68/18639 0.161764705882353 13.7051470588235 4.09983434787973e-10 2.30000706916053e-07 GO:0009055 electron transfer activity 12/220 116/18639 0.103448275862069 8.76442006269592 1.26701593340005e-08 3.55397969318715e-06 GO:0015078 proton transmembrane transporter activity 14/220 185/18639 0.0756756756756757 6.41144963144963 4.33557815053918e-08 8.10753114150826e-06 GO:0031625 ubiquitin protein ligase binding 17/220 302/18639 0.0562913907284768 4.76916014449127 1.19648578663573e-07 1.6780713157566e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 11/220 118/18639 0.0932203389830508 7.8978813559322 1.52782801769445e-07 1.71422303585317e-05 GO:0140313 molecular sequestering activity 8/220 55/18639 0.145454545454545 12.323305785124 2.50682173452583e-07 2.34387832178165e-05 GO:0044389 ubiquitin-like protein ligase binding 17/220 322/18639 0.0527950310559006 4.47293901750423 2.97655880623208e-07 2.38549927185171e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/220 41/18639 0.170731707317073 14.4648558758315 4.63759055021986e-07 3.25211037334168e-05 GO:0015399 primary active transmembrane transporter activity 12/220 166/18639 0.072289156626506 6.12453450164293 6.68384039428219e-07 4.1662605124359e-05 GO:0003954 NADH dehydrogenase activity 7/220 44/18639 0.159090909090909 13.4786157024793 7.67090701384408e-07 4.30337883476653e-05 GO:0048306 calcium-dependent protein binding 8/220 80/18639 0.1 8.47227272727273 4.63482281010289e-06 0.000236375963315247 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/220 58/18639 0.120689655172414 10.2251567398119 5.2324511927201e-06 0.000244617093259665 GO:0022804 active transmembrane transporter activity 18/220 457/18639 0.0393873085339169 3.3370001989258 8.65477032969425e-06 0.000373486627304498 GO:0044548 S100 protein binding 4/220 14/18639 0.285714285714286 24.2064935064935 1.72294183929894e-05 0.000690407408461932 GO:0046332 SMAD binding 7/220 79/18639 0.0886075949367089 7.50707710011507 4.090928511668e-05 0.00148250851118919 GO:0042277 peptide binding 12/220 249/18639 0.0481927710843374 4.08302300109529 4.22818826720625e-05 0.00148250851118919 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 14/220 349/18639 0.0401146131805158 3.39861943214379 7.28593211569148e-05 0.00240435759817819 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/220 88/18639 0.0795454545454545 6.73930785123967 8.19127110406714e-05 0.00255294616076759 GO:0051082 unfolded protein binding 8/220 121/18639 0.0661157024793388 5.6015026296018 9.51592971847329e-05 0.00274689499185135 GO:1901682 sulfur compound transmembrane transporter activity 6/220 63/18639 0.0952380952380952 8.06883116883117 9.79285202086041e-05 0.00274689499185135 GO:0038024 cargo receptor activity 6/220 65/18639 0.0923076923076923 7.82055944055944 0.000116738823807755 0.00311859429315003 GO:0005131 growth hormone receptor binding 3/220 10/18639 0.3 25.4168181818182 0.000183098496090463 0.00446601114377172 GO:0030957 Tat protein binding 3/220 10/18639 0.3 25.4168181818182 0.000183098496090463 0.00446601114377172 GO:0050750 low-density lipoprotein particle receptor binding 4/220 26/18639 0.153846153846154 13.0342657342657 0.000230246230567726 0.0053820056395206 GO:0050786 RAGE receptor binding 3/220 11/18639 0.272727272727273 23.1061983471074 0.000249570222957782 0.00560035580317262 GO:0005200 structural constituent of cytoskeleton 7/220 112/18639 0.0625 5.29517045454545 0.000368295268943138 0.00794667868758078 GO:0001540 amyloid-beta binding 6/220 83/18639 0.072289156626506 6.12453450164293 0.000447382948184472 0.00927102081188228 GO:0070325 lipoprotein particle receptor binding 4/220 31/18639 0.129032258064516 10.9319648093842 0.000462724746404107 0.00927102081188228 GO:0071813 lipoprotein particle binding 4/220 32/18639 0.125 10.5903409090909 0.000523971758728655 0.00979827188822584 GO:0071814 protein-lipid complex binding 4/220 32/18639 0.125 10.5903409090909 0.000523971758728655 0.00979827188822584 GO:0140311 protein sequestering activity 4/220 33/18639 0.121212121212121 10.2694214876033 0.000590770130341016 0.0103567374964127 GO:0045296 cadherin binding 12/220 334/18639 0.0359281437125748 3.04393032117583 0.000641655502700378 0.0103567374964127 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/220 484/18639 0.0309917355371901 2.62570435762585 0.000658838579061148 0.0103567374964127 GO:0051427 hormone receptor binding 4/220 34/18639 0.117647058823529 9.96737967914439 0.000663395318954712 0.0103567374964127 GO:0004129 cytochrome-c oxidase activity 3/220 15/18639 0.2 16.9445454545455 0.000664603475705627 0.0103567374964127 GO:0005041 low-density lipoprotein particle receptor activity 3/220 15/18639 0.2 16.9445454545455 0.000664603475705627 0.0103567374964127 GO:0140297 DNA-binding transcription factor binding 15/220 488/18639 0.0307377049180328 2.60418219076006 0.000716504463012555 0.0108637568581093 GO:0001216 DNA-binding transcription activator activity 15/220 491/18639 0.0305498981670061 2.58827069061285 0.000762524830271333 0.0112572744679531 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/220 16/18639 0.1875 15.8855113636364 0.000810877342453478 0.01137255472791 GO:0022858 alanine transmembrane transporter activity 3/220 16/18639 0.1875 15.8855113636364 0.000810877342453478 0.01137255472791 GO:0005201 extracellular matrix structural constituent 8/220 168/18639 0.0476190476190476 4.03441558441558 0.000877097530015222 0.0120012613253302 GO:0030169 low-density lipoprotein particle binding 3/220 17/18639 0.176470588235294 14.9510695187166 0.000976099566361609 0.0125314188052992 GO:0036041 long-chain fatty acid binding 3/220 17/18639 0.176470588235294 14.9510695187166 0.000976099566361609 0.0125314188052992 GO:0005179 hormone activity 7/220 132/18639 0.053030303030303 4.49287190082645 0.000982856376886211 0.0125314188052992 GO:0030228 lipoprotein particle receptor activity 3/220 18/18639 0.166666666666667 14.1204545454545 0.00116116939605228 0.0141612180692462 GO:0098641 cadherin binding involved in cell-cell adhesion 3/220 18/18639 0.166666666666667 14.1204545454545 0.00116116939605228 0.0141612180692462 GO:0140662 ATP-dependent protein folding chaperone 4/220 40/18639 0.1 8.47227272727273 0.00123704885762404 0.0147656257261082 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/220 41/18639 0.0975609756097561 8.26563192904656 0.00135823784761749 0.0158744048440294 GO:0004857 enzyme inhibitor activity 13/220 416/18639 0.03125 2.64758522727273 0.00138883670021446 0.0159007630371492 GO:0048156 tau protein binding 4/220 43/18639 0.0930232558139535 7.88118393234672 0.00162503852028263 0.0180529498399691 GO:0005126 cytokine receptor binding 10/220 275/18639 0.0363636363636364 3.08082644628099 0.00164117725817901 0.0180529498399691 GO:0030547 signaling receptor inhibitor activity 4/220 44/18639 0.0909090909090909 7.70206611570248 0.00177120079915622 0.0190405232658288 GO:0046943 carboxylic acid transmembrane transporter activity 8/220 188/18639 0.0425531914893617 3.60522243713733 0.001798837313884 0.0190405232658288 GO:0005342 organic acid transmembrane transporter activity 8/220 189/18639 0.0423280423280423 3.58614718614719 0.00185969894739271 0.0193202057312465 GO:0044183 protein folding chaperone 5/220 75/18639 0.0666666666666667 5.64818181818182 0.00193269952582952 0.0197135351634611 GO:0005504 fatty acid binding 4/220 47/18639 0.0851063829787234 7.21044487427466 0.00226400845848104 0.0226805133072833 GO:0033293 monocarboxylic acid binding 5/220 79/18639 0.0632911392405063 5.36219792865363 0.00242977902886749 0.0239141409683274 GO:0005540 hyaluronic acid binding 3/220 24/18639 0.125 10.5903409090909 0.0027338996516561 0.026027458340672 GO:0033218 amide binding 9/220 247/18639 0.0364372469635627 3.08706293706294 0.00273729062762861 0.026027458340672 GO:0004860 protein kinase inhibitor activity 5/220 84/18639 0.0595238095238095 5.04301948051948 0.00317434748063726 0.0296801489439584 GO:0070412 R-SMAD binding 3/220 26/18639 0.115384615384615 9.7756993006993 0.0034515832150428 0.031743248912115 GO:0005044 scavenger receptor activity 3/220 27/18639 0.111111111111111 9.41363636363636 0.00384955583610338 0.0348322713557096 GO:0019210 kinase inhibitor activity 5/220 90/18639 0.0555555555555556 4.70681818181818 0.00426967476739899 0.0380204372144577 GO:0031072 heat shock protein binding 6/220 131/18639 0.0458015267175573 3.88043025676613 0.00464802737619416 0.0407428649694519 GO:0004879 nuclear receptor activity 4/220 59/18639 0.0677966101694915 5.74391371340524 0.00517625481201376 0.0435944590302129 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/220 30/18639 0.1 8.47227272727273 0.00520646836902721 0.0435944590302129 GO:0048019 receptor antagonist activity 3/220 30/18639 0.1 8.47227272727273 0.00520646836902721 0.0435944590302129 GO:0098531 ligand-modulated transcription factor activity 4/220 60/18639 0.0666666666666667 5.64818181818182 0.00549560467060956 0.0446330303727327 GO:0002020 protease binding 6/220 136/18639 0.0441176470588235 3.73776737967914 0.00556918382547467 0.0446330303727327 GO:0044325 transmembrane transporter binding 6/220 136/18639 0.0441176470588235 3.73776737967914 0.00556918382547467 0.0446330303727327 GO:0015187 glycine transmembrane transporter activity 2/220 10/18639 0.2 16.9445454545455 0.00586338198146328 0.0450596889260397 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/220 10/18639 0.2 16.9445454545455 0.00586338198146328 0.0450596889260397 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/220 10/18639 0.2 16.9445454545455 0.00586338198146328 0.0450596889260397 GO:0015179 L-amino acid transmembrane transporter activity 4/220 62/18639 0.0645161290322581 5.46598240469208 0.00617322636615001 0.0467997296136508 GO:0031406 carboxylic acid binding 7/220 187/18639 0.0374331550802139 3.17143898881867 0.00687463888156719 0.0497468321545393 GO:0000099 sulfur amino acid transmembrane transporter activity 2/220 11/18639 0.181818181818182 15.404132231405 0.00711089570557562 0.0497468321545393 GO:0008199 ferric iron binding 2/220 11/18639 0.181818181818182 15.404132231405 0.00711089570557562 0.0497468321545393 GO:0048407 platelet-derived growth factor binding 2/220 11/18639 0.181818181818182 15.404132231405 0.00711089570557562 0.0497468321545393 GO:0050998 nitric-oxide synthase binding 2/220 11/18639 0.181818181818182 15.404132231405 0.00711089570557562 0.0497468321545393 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/220 11/18639 0.181818181818182 15.404132231405 0.00711089570557562 0.0497468321545393 GO:0015171 amino acid transmembrane transporter activity 5/220 102/18639 0.0490196078431373 4.15307486631016 0.0072257474849064 0.0497468321545393 GO:0043177 organic acid binding 7/220 189/18639 0.037037037037037 3.13787878787879 0.00727137297089522 0.0497468321545393 GO:0005154 epidermal growth factor receptor binding 3/220 35/18639 0.0857142857142857 7.26194805194805 0.00803881175088687 0.0543346191837052 GO:0004859 phospholipase inhibitor activity 2/220 12/18639 0.166666666666667 14.1204545454545 0.00846710144032968 0.0556628920069499 GO:0035259 nuclear glucocorticoid receptor binding 2/220 12/18639 0.166666666666667 14.1204545454545 0.00846710144032968 0.0556628920069499 GO:1990841 promoter-specific chromatin binding 4/220 68/18639 0.0588235294117647 4.98368983957219 0.00853299235757164 0.0556628920069499 GO:0001664 G protein-coupled receptor binding 9/220 297/18639 0.0303030303030303 2.56735537190083 0.00893684131681844 0.057627218146381 GO:0043394 proteoglycan binding 3/220 37/18639 0.0810810810810811 6.86941031941032 0.00938047508859584 0.0594659091476981 GO:0097110 scaffold protein binding 4/220 70/18639 0.0571428571428571 4.8412987012987 0.00943398558671146 0.0594659091476981 GO:0035325 Toll-like receptor binding 2/220 13/18639 0.153846153846154 13.0342657342657 0.00992928339737665 0.0618925331769811 GO:0051015 actin filament binding 7/220 209/18639 0.0334928229665072 2.83760330578512 0.0122257206193498 0.0753695523896181 GO:0042287 MHC protein binding 3/220 41/18639 0.0731707317073171 6.19922394678492 0.0124345823269335 0.0758239204935839 GO:0017081 chloride channel regulator activity 2/220 15/18639 0.133333333333333 11.2963636363636 0.013160954367045 0.0775855253947443 GO:0031386 protein tag activity 2/220 15/18639 0.133333333333333 11.2963636363636 0.013160954367045 0.0775855253947443 GO:0141047 molecular tag activity 2/220 15/18639 0.133333333333333 11.2963636363636 0.013160954367045 0.0775855253947443 GO:0008307 structural constituent of muscle 3/220 42/18639 0.0714285714285714 6.05162337662338 0.013276667447229 0.0775855253947443 GO:0008200 ion channel inhibitor activity 3/220 43/18639 0.0697674418604651 5.91088794926004 0.01415053961675 0.0818397188143992 GO:0008514 organic anion transmembrane transporter activity 8/220 269/18639 0.0297397769516729 2.51963501182832 0.0148168286506975 0.0844660948670429 GO:0055102 lipase inhibitor activity 2/220 16/18639 0.125 10.5903409090909 0.0149252510848438 0.0844660948670429 GO:0016248 channel inhibitor activity 3/220 44/18639 0.0681818181818182 5.77654958677686 0.0150563448960861 0.0844660948670429 GO:0015101 organic cation transmembrane transporter activity 4/220 81/18639 0.0493827160493827 4.18383838383838 0.0154935650638471 0.0860583168397842 GO:0008009 chemokine activity 3/220 45/18639 0.0666666666666667 5.64818181818182 0.0159942098298754 0.0871140943161176 GO:0141110 transporter inhibitor activity 3/220 45/18639 0.0666666666666667 5.64818181818182 0.0159942098298754 0.0871140943161176 GO:0003779 actin binding 11/220 443/18639 0.0248306997742664 2.10372460496614 0.0164637117879514 0.088809060702315 GO:0046965 nuclear retinoid X receptor binding 2/220 17/18639 0.117647058823529 9.96737967914439 0.0167851379539747 0.0888345508696209 GO:0051787 misfolded protein binding 2/220 17/18639 0.117647058823529 9.96737967914439 0.0167851379539747 0.0888345508696209 GO:0030291 protein serine/threonine kinase inhibitor activity 3/220 46/18639 0.0652173913043478 5.525395256917 0.0169642420170164 0.0889433623508991 GO:0030246 carbohydrate binding 8/220 280/18639 0.0285714285714286 2.42064935064935 0.0183977422607292 0.0955660500765655 GO:0016209 antioxidant activity 4/220 86/18639 0.0465116279069767 3.94059196617336 0.0189021082263535 0.0972851625227921 GO:0034987 immunoglobulin receptor binding 2/220 19/18639 0.105263157894737 8.91818181818182 0.0207818031262329 0.105987195943788 GO:0048020 CCR chemokine receptor binding 3/220 50/18639 0.06 5.08336363636364 0.0211675630958079 0.106982008078813 GO:0051087 protein-folding chaperone binding 5/220 134/18639 0.0373134328358209 3.16129579375848 0.0214601754751764 0.107492486085482 GO:0042288 MHC class I protein binding 2/220 20/18639 0.1 8.47227272727273 0.0229137531729752 0.113757659557868 GO:0072542 protein phosphatase activator activity 2/220 21/18639 0.0952380952380952 8.06883116883117 0.0251316354613058 0.123674100822741 GO:0098632 cell-cell adhesion mediator activity 3/220 55/18639 0.0545454545454545 4.62123966942149 0.0271511319205073 0.132450304412214 GO:0099186 structural constituent of postsynapse 2/220 23/18639 0.0869565217391304 7.36719367588933 0.0298160147922221 0.144196416365833 GO:0035035 histone acetyltransferase binding 2/220 24/18639 0.0833333333333333 7.06022727272727 0.0322780252595463 0.154606211869889 GO:0015459 potassium channel regulator activity 3/220 59/18639 0.0508474576271186 4.30793528505393 0.0325196666678198 0.154606211869889 GO:0019211 phosphatase activator activity 2/220 25/18639 0.08 6.77781818181818 0.0348169935007186 0.162769444615859 GO:0042974 nuclear retinoic acid receptor binding 2/220 25/18639 0.08 6.77781818181818 0.0348169935007186 0.162769444615859 GO:0005516 calmodulin binding 6/220 207/18639 0.0289855072463768 2.45573122529644 0.0364964945507804 0.169211020189982 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/220 26/18639 0.0769230769230769 6.51713286713287 0.0374307776911916 0.170720864103727 GO:0008198 ferrous iron binding 2/220 26/18639 0.0769230769230769 6.51713286713287 0.0374307776911916 0.170720864103727 GO:0023026 MHC class II protein complex binding 2/220 27/18639 0.0740740740740741 6.27575757575758 0.0401172754395986 0.1814983187227 GO:0004222 metalloendopeptidase activity 4/220 110/18639 0.0363636363636364 3.08082644628099 0.0414277626420958 0.184452760715274 GO:0099106 ion channel regulator activity 5/220 160/18639 0.03125 2.64758522727273 0.0414278927809706 0.184452760715274 GO:0005178 integrin binding 5/220 161/18639 0.031055900621118 2.6311405985319 0.0423625771696219 0.18712917946581 GO:0003924 GTPase activity 8/220 331/18639 0.0241691842900302 2.04767920900851 0.0432507517384492 0.188347802976802 GO:0008083 growth factor activity 5/220 162/18639 0.0308641975308642 2.61489898989899 0.0433099226096391 0.188347802976802 GO:0005416 amino acid:monoatomic cation symporter activity 2/220 29/18639 0.0689655172413793 5.84294670846395 0.0457001954669141 0.197213920437991 GO:0001965 G-protein alpha-subunit binding 2/220 30/18639 0.0666666666666667 5.64818181818182 0.0485926045453346 0.206518569317672 GO:0098918 structural constituent of synapse 2/220 30/18639 0.0666666666666667 5.64818181818182 0.0485926045453346 0.206518569317672 GO:0016247 channel regulator activity 5/220 168/18639 0.0297619047619048 2.52150974025974 0.0492608621039729 0.207784538649089 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/220 70/18639 0.0428571428571429 3.63097402597403 0.0498930521526959 0.208880613863152 GO:0141108 transporter regulator activity 5/220 170/18639 0.0294117647058824 2.4918449197861 0.0513464832183316 0.213373163596178 GO:0061134 peptidase regulator activity 6/220 226/18639 0.0265486725663717 2.24927594529364 0.0519732358474097 0.214389597870565 GO:0005518 collagen binding 3/220 72/18639 0.0416666666666667 3.53011363636364 0.0534511703264351 0.217290627196595 GO:0042379 chemokine receptor binding 3/220 72/18639 0.0416666666666667 3.53011363636364 0.0534511703264351 0.217290627196595 GO:0019207 kinase regulator activity 7/220 287/18639 0.024390243902439 2.06640798226164 0.0544385282156293 0.219712333301928 GO:0071889 14-3-3 protein binding 2/220 33/18639 0.0606060606060606 5.13471074380165 0.0576503255983296 0.231013090433307 GO:0003725 double-stranded RNA binding 3/220 75/18639 0.04 3.38890909090909 0.0590104260988801 0.234786163414693 GO:0015035 protein-disulfide reductase activity 2/220 34/18639 0.0588235294117647 4.98368983957219 0.0607901346124999 0.239000796476914 GO:0098631 cell adhesion mediator activity 3/220 76/18639 0.0394736842105263 3.34431818181818 0.0609217716509781 0.239000796476914 GO:0023023 MHC protein complex binding 2/220 37/18639 0.0540540540540541 4.57960687960688 0.0705459421036812 0.274835232778925 GO:0015297 antiporter activity 4/220 135/18639 0.0296296296296296 2.51030303030303 0.0760607612452525 0.294276462473011 GO:0016922 nuclear receptor binding 4/220 137/18639 0.0291970802919708 2.47365627073656 0.0793113714807442 0.304751228771901 GO:0015036 disulfide oxidoreductase activity 2/220 40/18639 0.05 4.23613636363636 0.0807701007452514 0.306162341338419 GO:0071855 neuropeptide receptor binding 2/220 40/18639 0.05 4.23613636363636 0.0807701007452514 0.306162341338419 GO:0019887 protein kinase regulator activity 6/220 255/18639 0.0235294117647059 1.99347593582888 0.082317495953335 0.309037286791064 GO:0070851 growth factor receptor binding 4/220 139/18639 0.0287769784172662 2.4380640941792 0.0826302905858461 0.309037286791064 GO:0017080 sodium channel regulator activity 2/220 41/18639 0.0487804878048781 4.13281596452328 0.0842744863051652 0.313099250445018 GO:0035198 miRNA binding 2/220 42/18639 0.0476190476190476 4.03441558441558 0.087824377248062 0.319931659975083 GO:0042056 chemoattractant activity 2/220 42/18639 0.0476190476190476 4.03441558441558 0.087824377248062 0.319931659975083 GO:0048487 beta-tubulin binding 2/220 42/18639 0.0476190476190476 4.03441558441558 0.087824377248062 0.319931659975083 GO:0072341 modified amino acid binding 3/220 91/18639 0.032967032967033 2.79305694305694 0.0928817003027042 0.336171831418175 GO:0001046 core promoter sequence-specific DNA binding 2/220 44/18639 0.0454545454545455 3.85103305785124 0.0950545028952266 0.339653351109695 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/220 44/18639 0.0454545454545455 3.85103305785124 0.0950545028952266 0.339653351109695 GO:0042605 peptide antigen binding 2/220 45/18639 0.0444444444444444 3.76545454545455 0.0987317258284987 0.350560115125239 GO:0004867 serine-type endopeptidase inhibitor activity 3/220 95/18639 0.0315789473684211 2.67545454545455 0.102370759646595 0.359209806418629 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/220 46/18639 0.0434782608695652 3.68359683794466 0.102448429638112 0.359209806418629 GO:0005506 iron ion binding 4/220 154/18639 0.025974025974026 2.20059031877214 0.109617063760544 0.367378882033184 GO:0038187 pattern recognition receptor activity 2/220 48/18639 0.0416666666666667 3.53011363636364 0.109994573466404 0.367378882033184 GO:0004955 prostaglandin receptor activity 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0005381 iron ion transmembrane transporter activity 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0005522 profilin binding 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0005528 FK506 binding 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0019531 oxalate transmembrane transporter activity 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0043208 glycosphingolipid binding 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0070513 death domain binding 1/220 10/18639 0.1 8.47227272727273 0.111981798266799 0.367378882033184 GO:0002162 dystroglycan binding 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0004954 prostanoid receptor activity 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0008271 secondary active sulfate transmembrane transporter activity 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0010854 adenylate cyclase regulator activity 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0015173 aromatic amino acid transmembrane transporter activity 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0019215 intermediate filament binding 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0032794 GTPase activating protein binding 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0097493 structural molecule activity conferring elasticity 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/220 11/18639 0.0909090909090909 7.70206611570248 0.122468888522922 0.376171971423263 GO:0004866 endopeptidase inhibitor activity 4/220 161/18639 0.0248447204968944 2.10491247882552 0.123404470876279 0.376171971423263 GO:0015291 secondary active transmembrane transporter activity 6/220 287/18639 0.0209059233449477 1.77120684193855 0.125092796474833 0.376171971423263 GO:0005080 protein kinase C binding 2/220 52/18639 0.0384615384615385 3.25856643356643 0.125499407087019 0.376171971423263 GO:0005544 calcium-dependent phospholipid binding 2/220 53/18639 0.0377358490566038 3.19708404802744 0.129453875501699 0.376171971423263 GO:0008013 beta-catenin binding 3/220 106/18639 0.0283018867924528 2.39781303602058 0.13029826700614 0.376171971423263 GO:0004126 cytidine deaminase activity 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0004875 complement receptor activity 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0005049 nuclear export signal receptor activity 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0005527 macrolide binding 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0016208 AMP binding 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0035497 cAMP response element binding 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0097677 STAT family protein binding 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0140900 chloride:bicarbonate antiporter activity 1/220 12/18639 0.0833333333333333 7.06022727272727 0.132832687348612 0.376171971423263 GO:0019888 protein phosphatase regulator activity 3/220 107/18639 0.0280373831775701 2.37540356839422 0.132959620295195 0.376171971423263 GO:0015485 cholesterol binding 2/220 54/18639 0.037037037037037 3.13787878787879 0.133437116422869 0.376171971423263 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/220 54/18639 0.037037037037037 3.13787878787879 0.133437116422869 0.376171971423263 GO:0030414 peptidase inhibitor activity 4/220 169/18639 0.0236686390532544 2.0052716514255 0.140013158964737 0.385888806429287 GO:0170055 lipid transmembrane transporter activity 2/220 56/18639 0.0357142857142857 3.02581168831169 0.141485054132822 0.385888806429287 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0005172 vascular endothelial growth factor receptor binding 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0005542 folic acid binding 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0031432 titin binding 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0039706 co-receptor binding 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0071714 icosanoid transmembrane transporter activity 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0071837 HMG box domain binding 1/220 13/18639 0.0769230769230769 6.51713286713287 0.143074637677882 0.385888806429287 GO:0005125 cytokine activity 5/220 234/18639 0.0213675213675214 1.81031468531469 0.144102451853899 0.386801318134149 GO:0004601 peroxidase activity 2/220 57/18639 0.0350877192982456 2.97272727272727 0.145547381156724 0.386976686392996 GO:0016504 peptidase activator activity 2/220 57/18639 0.0350877192982456 2.97272727272727 0.145547381156724 0.386976686392996 GO:0046982 protein heterodimerization activity 7/220 369/18639 0.018970189701897 1.60720620842572 0.147661680280699 0.388512731618925 GO:0061980 regulatory RNA binding 2/220 58/18639 0.0344827586206897 2.92147335423197 0.149633740351889 0.388512731618925 GO:0005161 platelet-derived growth factor receptor binding 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:0005313 L-glutamate transmembrane transporter activity 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:0005545 1-phosphatidylinositol binding 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:0008559 ABC-type xenobiotic transporter activity 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:0015926 glucosidase activity 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:0061665 SUMO ligase activity 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:1990825 sequence-specific mRNA binding 1/220 14/18639 0.0714285714285714 6.05162337662338 0.153196165634011 0.388512731618925 GO:0001786 phosphatidylserine binding 2/220 59/18639 0.0338983050847458 2.87195685670262 0.15374300609519 0.388512731618925 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/220 59/18639 0.0338983050847458 2.87195685670262 0.15374300609519 0.388512731618925 GO:0001221 transcription coregulator binding 3/220 115/18639 0.0260869565217391 2.2101581027668 0.15490332505998 0.389593446325317 GO:0005539 glycosaminoglycan binding 5/220 242/18639 0.0206611570247934 1.75046957175056 0.158911083341847 0.389593446325317 GO:0019208 phosphatase regulator activity 3/220 117/18639 0.0256410256410256 2.17237762237762 0.160558044718449 0.389593446325317 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/220 61/18639 0.0327868852459016 2.77779433681073 0.162025869350689 0.389593446325317 GO:0004953 icosanoid receptor activity 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0005523 tropomyosin binding 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0015116 sulfate transmembrane transporter activity 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0033130 acetylcholine receptor binding 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0045504 dynein heavy chain binding 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0048531 beta-1,3-galactosyltransferase activity 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0120283 protein serine/threonine kinase binding 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0140161 monocarboxylate:sodium symporter activity 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0140776 protein-containing complex destabilizing activity 1/220 15/18639 0.0666666666666667 5.64818181818182 0.163198680724509 0.389593446325317 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/220 16/18639 0.0625 5.29517045454545 0.17308357603382 0.403526852102716 GO:0008142 oxysterol binding 1/220 16/18639 0.0625 5.29517045454545 0.17308357603382 0.403526852102716 GO:0015378 sodium:chloride symporter activity 1/220 16/18639 0.0625 5.29517045454545 0.17308357603382 0.403526852102716 GO:0016722 oxidoreductase activity, acting on metal ions 1/220 16/18639 0.0625 5.29517045454545 0.17308357603382 0.403526852102716 GO:0008237 metallopeptidase activity 4/220 184/18639 0.0217391304347826 1.84179841897233 0.173351107587798 0.403526852102716 GO:0061135 endopeptidase regulator activity 4/220 184/18639 0.0217391304347826 1.84179841897233 0.173351107587798 0.403526852102716 GO:0008429 phosphatidylethanolamine binding 1/220 17/18639 0.0588235294117647 4.98368983957219 0.18285222841381 0.416992276992469 GO:0030548 acetylcholine receptor regulator activity 1/220 17/18639 0.0588235294117647 4.98368983957219 0.18285222841381 0.416992276992469 GO:0048038 quinone binding 1/220 17/18639 0.0588235294117647 4.98368983957219 0.18285222841381 0.416992276992469 GO:0070402 NADPH binding 1/220 17/18639 0.0588235294117647 4.98368983957219 0.18285222841381 0.416992276992469 GO:1990226 histone methyltransferase binding 1/220 17/18639 0.0588235294117647 4.98368983957219 0.18285222841381 0.416992276992469 GO:0032934 sterol binding 2/220 68/18639 0.0294117647058824 2.4918449197861 0.191582552270784 0.420632059629734 GO:0000900 mRNA regulatory element binding translation repressor activity 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0003746 translation elongation factor activity 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0015172 acidic amino acid transmembrane transporter activity 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0015373 monoatomic anion:sodium symporter activity 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0050811 GABA receptor binding 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0099602 neurotransmitter receptor regulator activity 1/220 18/18639 0.0555555555555556 4.70681818181818 0.192505998672051 0.420632059629734 GO:0031490 chromatin DNA binding 3/220 128/18639 0.0234375 1.98568892045455 0.19269597027601 0.420632059629734 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/220 128/18639 0.0234375 1.98568892045455 0.19269597027601 0.420632059629734 GO:0019001 guanyl nucleotide binding 7/220 400/18639 0.0175 1.48264772727273 0.195321599390821 0.423071109105214 GO:0032561 guanyl ribonucleotide binding 7/220 400/18639 0.0175 1.48264772727273 0.195321599390821 0.423071109105214 GO:0015245 fatty acid transmembrane transporter activity 1/220 19/18639 0.0526315789473684 4.45909090909091 0.20204623175793 0.429348242485601 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/220 19/18639 0.0526315789473684 4.45909090909091 0.20204623175793 0.429348242485601 GO:0030506 ankyrin binding 1/220 19/18639 0.0526315789473684 4.45909090909091 0.20204623175793 0.429348242485601 GO:0043395 heparan sulfate proteoglycan binding 1/220 19/18639 0.0526315789473684 4.45909090909091 0.20204623175793 0.429348242485601 GO:0097001 ceramide binding 1/220 19/18639 0.0526315789473684 4.45909090909091 0.20204623175793 0.429348242485601 GO:0001972 retinoic acid binding 1/220 20/18639 0.05 4.23613636363636 0.211474256946611 0.442675590100929 GO:0010851 cyclase regulator activity 1/220 20/18639 0.05 4.23613636363636 0.211474256946611 0.442675590100929 GO:0016004 phospholipase activator activity 1/220 20/18639 0.05 4.23613636363636 0.211474256946611 0.442675590100929 GO:0043024 ribosomal small subunit binding 1/220 20/18639 0.05 4.23613636363636 0.211474256946611 0.442675590100929 GO:0005096 GTPase activator activity 5/220 271/18639 0.018450184501845 1.56314994968131 0.217227930453446 0.452058279852963 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/220 21/18639 0.0476190476190476 4.03441558441558 0.220791388020877 0.452058279852963 GO:0001846 opsonin binding 1/220 21/18639 0.0476190476190476 4.03441558441558 0.220791388020877 0.452058279852963 GO:0015125 bile acid transmembrane transporter activity 1/220 21/18639 0.0476190476190476 4.03441558441558 0.220791388020877 0.452058279852963 GO:0051428 peptide hormone receptor binding 1/220 21/18639 0.0476190476190476 4.03441558441558 0.220791388020877 0.452058279852963 GO:0070182 DNA polymerase binding 1/220 21/18639 0.0476190476190476 4.03441558441558 0.220791388020877 0.452058279852963 GO:0015377 chloride:monoatomic cation symporter activity 1/220 22/18639 0.0454545454545455 3.85103305785124 0.229998923450859 0.464134518186805 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/220 22/18639 0.0454545454545455 3.85103305785124 0.229998923450859 0.464134518186805 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/220 22/18639 0.0454545454545455 3.85103305785124 0.229998923450859 0.464134518186805 GO:0033691 sialic acid binding 1/220 22/18639 0.0454545454545455 3.85103305785124 0.229998923450859 0.464134518186805 GO:0020037 heme binding 3/220 142/18639 0.0211267605633803 1.78991677336748 0.23561809813338 0.467042526009753 GO:0004602 glutathione peroxidase activity 1/220 23/18639 0.0434782608695652 3.68359683794466 0.239098146571706 0.467042526009753 GO:0005212 structural constituent of eye lens 1/220 23/18639 0.0434782608695652 3.68359683794466 0.239098146571706 0.467042526009753 GO:0005283 amino acid:sodium symporter activity 1/220 23/18639 0.0434782608695652 3.68359683794466 0.239098146571706 0.467042526009753 GO:0016917 GABA receptor activity 1/220 23/18639 0.0434782608695652 3.68359683794466 0.239098146571706 0.467042526009753 GO:0070577 lysine-acetylated histone binding 1/220 23/18639 0.0434782608695652 3.68359683794466 0.239098146571706 0.467042526009753 GO:0031267 small GTPase binding 5/220 283/18639 0.0176678445229682 1.49686797301638 0.243107043643233 0.467042526009753 GO:0033192 calmodulin-dependent protein phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0140791 histone H2AXS140 phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/220 81/18639 0.0246913580246914 2.09191919191919 0.247935581788564 0.467042526009753 GO:0015295 solute:proton symporter activity 1/220 24/18639 0.0416666666666667 3.53011363636364 0.248090325759192 0.467042526009753 GO:0019957 C-C chemokine binding 1/220 24/18639 0.0416666666666667 3.53011363636364 0.248090325759192 0.467042526009753 GO:0050699 WW domain binding 1/220 24/18639 0.0416666666666667 3.53011363636364 0.248090325759192 0.467042526009753 GO:0060229 lipase activator activity 1/220 24/18639 0.0416666666666667 3.53011363636364 0.248090325759192 0.467042526009753 GO:0140033 acetylation-dependent protein binding 1/220 24/18639 0.0416666666666667 3.53011363636364 0.248090325759192 0.467042526009753 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/220 82/18639 0.024390243902439 2.06640798226164 0.252309385357568 0.468064730170286 GO:0033549 MAP kinase phosphatase activity 2/220 82/18639 0.024390243902439 2.06640798226164 0.252309385357568 0.468064730170286 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/220 83/18639 0.0240963855421687 2.04151150054764 0.25668517051565 0.468064730170286 GO:0008135 translation factor activity, RNA binding 2/220 83/18639 0.0240963855421687 2.04151150054764 0.25668517051565 0.468064730170286 GO:0001848 complement binding 1/220 25/18639 0.04 3.38890909090909 0.256976714603294 0.468064730170286 GO:0008139 nuclear localization sequence binding 1/220 25/18639 0.04 3.38890909090909 0.256976714603294 0.468064730170286 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/220 25/18639 0.04 3.38890909090909 0.256976714603294 0.468064730170286 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/220 25/18639 0.04 3.38890909090909 0.256976714603294 0.468064730170286 GO:0019707 protein-cysteine S-acyltransferase activity 1/220 25/18639 0.04 3.38890909090909 0.256976714603294 0.468064730170286 GO:0120020 cholesterol transfer activity 1/220 25/18639 0.04 3.38890909090909 0.256976714603294 0.468064730170286 GO:0017018 myosin phosphatase activity 2/220 84/18639 0.0238095238095238 2.01720779220779 0.261062284290565 0.470919426003238 GO:0051117 ATPase binding 2/220 84/18639 0.0238095238095238 2.01720779220779 0.261062284290565 0.470919426003238 GO:0180051 translation factor activity 2/220 84/18639 0.0238095238095238 2.01720779220779 0.261062284290565 0.470919426003238 GO:0030247 polysaccharide binding 1/220 26/18639 0.0384615384615385 3.25856643356643 0.265758552079778 0.473303326084939 GO:0030507 spectrin binding 1/220 26/18639 0.0384615384615385 3.25856643356643 0.265758552079778 0.473303326084939 GO:0050681 nuclear androgen receptor binding 1/220 26/18639 0.0384615384615385 3.25856643356643 0.265758552079778 0.473303326084939 GO:0051139 metal cation:proton antiporter activity 1/220 26/18639 0.0384615384615385 3.25856643356643 0.265758552079778 0.473303326084939 GO:0046906 tetrapyrrole binding 3/220 152/18639 0.0197368421052632 1.67215909090909 0.267222699517316 0.474404855788653 GO:0001671 ATPase activator activity 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0004364 glutathione transferase activity 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0008320 protein transmembrane transporter activity 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0008395 steroid hydroxylase activity 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0015252 proton channel activity 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0035255 ionotropic glutamate receptor binding 1/220 27/18639 0.037037037037037 3.13787878787879 0.274437062719786 0.47518269193148 GO:0004197 cysteine-type endopeptidase activity 2/220 88/18639 0.0227272727272727 1.92551652892562 0.278571485698793 0.476788436192677 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/220 89/18639 0.0224719101123595 1.90388151174668 0.282945963970029 0.476788436192677 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/220 89/18639 0.0224719101123595 1.90388151174668 0.282945963970029 0.476788436192677 GO:0019789 SUMO transferase activity 1/220 28/18639 0.0357142857142857 3.02581168831169 0.283013456777471 0.476788436192677 GO:0046625 sphingolipid binding 1/220 28/18639 0.0357142857142857 3.02581168831169 0.283013456777471 0.476788436192677 GO:0050698 proteoglycan sulfotransferase activity 1/220 28/18639 0.0357142857142857 3.02581168831169 0.283013456777471 0.476788436192677 GO:0051019 mitogen-activated protein kinase binding 1/220 28/18639 0.0357142857142857 3.02581168831169 0.283013456777471 0.476788436192677 GO:0051393 alpha-actinin binding 1/220 28/18639 0.0357142857142857 3.02581168831169 0.283013456777471 0.476788436192677 GO:0097718 disordered domain specific binding 1/220 28/18639 0.0357142857142857 3.02581168831169 0.283013456777471 0.476788436192677 GO:0140793 histone H2AXY142 phosphatase activity 2/220 90/18639 0.0222222222222222 1.88272727272727 0.287318159065888 0.482375486584043 GO:0005525 GTP binding 6/220 378/18639 0.0158730158730159 1.34480519480519 0.289004428754583 0.482375486584043 GO:0003785 actin monomer binding 1/220 29/18639 0.0344827586206897 2.92147335423197 0.291488930395705 0.482375486584043 GO:0016417 S-acyltransferase activity 1/220 29/18639 0.0344827586206897 2.92147335423197 0.291488930395705 0.482375486584043 GO:0035250 UDP-galactosyltransferase activity 1/220 29/18639 0.0344827586206897 2.92147335423197 0.291488930395705 0.482375486584043 GO:0051861 glycolipid binding 1/220 29/18639 0.0344827586206897 2.92147335423197 0.291488930395705 0.482375486584043 GO:0043178 alcohol binding 2/220 92/18639 0.0217391304347826 1.84179841897233 0.296053499805498 0.488488274679071 GO:0001968 fibronectin binding 1/220 30/18639 0.0333333333333333 2.82409090909091 0.299864665769856 0.493325740460085 GO:0015631 tubulin binding 6/220 385/18639 0.0155844155844156 1.32035419126328 0.303323392771723 0.49707677139899 GO:0005164 tumor necrosis factor receptor binding 1/220 31/18639 0.032258064516129 2.73299120234604 0.308141831309683 0.49707677139899 GO:0005184 neuropeptide hormone activity 1/220 31/18639 0.032258064516129 2.73299120234604 0.308141831309683 0.49707677139899 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/220 31/18639 0.032258064516129 2.73299120234604 0.308141831309683 0.49707677139899 GO:0005452 solute:inorganic anion antiporter activity 1/220 31/18639 0.032258064516129 2.73299120234604 0.308141831309683 0.49707677139899 GO:0072349 modified amino acid transmembrane transporter activity 1/220 31/18639 0.032258064516129 2.73299120234604 0.308141831309683 0.49707677139899 GO:0015103 inorganic anion transmembrane transporter activity 3/220 165/18639 0.0181818181818182 1.5404132231405 0.308957150679079 0.49707677139899 GO:0051020 GTPase binding 5/220 315/18639 0.0158730158730159 1.34480519480519 0.315439588616537 0.49707677139899 GO:0008378 galactosyltransferase activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0015106 bicarbonate transmembrane transporter activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0022884 macromolecule transmembrane transporter activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0042910 xenobiotic transmembrane transporter activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0051059 NF-kappaB binding 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0120015 sterol transfer activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0140142 nucleocytoplasmic carrier activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0160041 neuropeptide activity 1/220 32/18639 0.03125 2.64758522727273 0.316321581799358 0.49707677139899 GO:0004725 protein tyrosine phosphatase activity 2/220 98/18639 0.0204081632653061 1.72903525046382 0.322149856527431 0.502738226104182 GO:0019239 deaminase activity 1/220 33/18639 0.0303030303030303 2.56735537190083 0.324405058555639 0.502738226104182 GO:0019956 chemokine binding 1/220 33/18639 0.0303030303030303 2.56735537190083 0.324405058555639 0.502738226104182 GO:0042923 neuropeptide binding 1/220 33/18639 0.0303030303030303 2.56735537190083 0.324405058555639 0.502738226104182 GO:0140416 transcription regulator inhibitor activity 1/220 33/18639 0.0303030303030303 2.56735537190083 0.324405058555639 0.502738226104182 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/220 34/18639 0.0294117647058824 2.4918449197861 0.332393389584219 0.510884086456841 GO:0019825 oxygen binding 1/220 34/18639 0.0294117647058824 2.4918449197861 0.332393389584219 0.510884086456841 GO:0030332 cyclin binding 1/220 34/18639 0.0294117647058824 2.4918449197861 0.332393389584219 0.510884086456841 GO:0003823 antigen binding 3/220 174/18639 0.0172413793103448 1.46073667711599 0.338006153275458 0.518055434908534 GO:0140104 molecular carrier activity 4/220 249/18639 0.0160642570281124 1.36100766703176 0.338906140127329 0.518055434908534 GO:0005343 organic acid:sodium symporter activity 1/220 35/18639 0.0285714285714286 2.42064935064935 0.340287689734258 0.518753787882932 GO:0004722 protein serine/threonine phosphatase activity 2/220 103/18639 0.0194174757281553 1.64510150044131 0.343714593499712 0.519356284940131 GO:0004175 endopeptidase activity 6/220 405/18639 0.0148148148148148 1.25515151515152 0.344865686413745 0.519356284940131 GO:0043021 ribonucleoprotein complex binding 3/220 177/18639 0.0169491525423729 1.43597842835131 0.347682087200285 0.519356284940131 GO:0005484 SNAP receptor activity 1/220 36/18639 0.0277777777777778 2.35340909090909 0.34808906085114 0.519356284940131 GO:0016409 palmitoyltransferase activity 1/220 36/18639 0.0277777777777778 2.35340909090909 0.34808906085114 0.519356284940131 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/220 36/18639 0.0277777777777778 2.35340909090909 0.34808906085114 0.519356284940131 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/220 36/18639 0.0277777777777778 2.35340909090909 0.34808906085114 0.519356284940131 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/220 36/18639 0.0277777777777778 2.35340909090909 0.34808906085114 0.519356284940131 GO:0005319 lipid transporter activity 3/220 178/18639 0.0168539325842697 1.42791113381001 0.350904716723026 0.52216855724567 GO:0042805 actinin binding 1/220 37/18639 0.027027027027027 2.28980343980344 0.355798591927458 0.526380277670461 GO:0030695 GTPase regulator activity 7/220 489/18639 0.0143149284253579 1.21279977691021 0.356346592665134 0.526380277670461 GO:0004497 monooxygenase activity 2/220 106/18639 0.0188679245283019 1.59854202401372 0.356549920703699 0.526380277670461 GO:0060589 nucleoside-triphosphatase regulator activity 7/220 490/18639 0.0142857142857143 1.21032467532468 0.358269733228803 0.527531024518001 GO:0000146 microfilament motor activity 1/220 38/18639 0.0263157894736842 2.22954545454545 0.36341735925226 0.530930048282598 GO:0005501 retinoid binding 1/220 38/18639 0.0263157894736842 2.22954545454545 0.36341735925226 0.530930048282598 GO:0019840 isoprenoid binding 1/220 38/18639 0.0263157894736842 2.22954545454545 0.36341735925226 0.530930048282598 GO:0005496 steroid binding 2/220 108/18639 0.0185185185185185 1.56893939393939 0.365057252892658 0.53194056850073 GO:0016887 ATP hydrolysis activity 6/220 417/18639 0.0143884892086331 1.2190320470896 0.370073380642558 0.5377285408252 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/220 39/18639 0.0256410256410256 2.17237762237762 0.370946426558561 0.5377285408252 GO:0071949 FAD binding 1/220 40/18639 0.025 2.11806818181818 0.378386845169158 0.547100567370871 GO:0043022 ribosome binding 2/220 112/18639 0.0178571428571429 1.51290584415584 0.381940386713787 0.54923844155575 GO:0140597 protein carrier chaperone 3/220 188/18639 0.0159574468085106 1.3519584139265 0.383005011832727 0.54923844155575 GO:0001530 lipopolysaccharide binding 1/220 41/18639 0.024390243902439 2.06640798226164 0.385739654140758 0.54923844155575 GO:0042169 SH2 domain binding 1/220 41/18639 0.024390243902439 2.06640798226164 0.385739654140758 0.54923844155575 GO:0140318 protein transporter activity 1/220 41/18639 0.024390243902439 2.06640798226164 0.385739654140758 0.54923844155575 GO:0140828 metal cation:monoatomic cation antiporter activity 1/220 41/18639 0.024390243902439 2.06640798226164 0.385739654140758 0.54923844155575 GO:0016859 cis-trans isomerase activity 1/220 42/18639 0.0238095238095238 2.01720779220779 0.393005880406434 0.55535591664486 GO:0019894 kinesin binding 1/220 42/18639 0.0238095238095238 2.01720779220779 0.393005880406434 0.55535591664486 GO:0031492 nucleosomal DNA binding 1/220 42/18639 0.0238095238095238 2.01720779220779 0.393005880406434 0.55535591664486 GO:0017124 SH3 domain binding 2/220 115/18639 0.0173913043478261 1.47343873517787 0.394477510653183 0.556034883106622 GO:0015294 solute:monoatomic cation symporter activity 2/220 116/18639 0.0172413793103448 1.46073667711599 0.398631102808139 0.559861965915518 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/220 43/18639 0.0232558139534884 1.97029598308668 0.40018653891644 0.559861965915518 GO:0008375 acetylglucosaminyltransferase activity 1/220 43/18639 0.0232558139534884 1.97029598308668 0.40018653891644 0.559861965915518 GO:0008017 microtubule binding 4/220 276/18639 0.0144927536231884 1.22786561264822 0.411041469522426 0.573617573139505 GO:0046915 transition metal ion transmembrane transporter activity 1/220 45/18639 0.0222222222222222 1.88272727272727 0.414295153389873 0.576723526182925 GO:0015108 chloride transmembrane transporter activity 2/220 121/18639 0.0165289256198347 1.40037565740045 0.419195967153956 0.582101330627151 GO:0004180 carboxypeptidase activity 1/220 46/18639 0.0217391304347826 1.84179841897233 0.421225080584357 0.583474741253887 GO:0001784 phosphotyrosine residue binding 1/220 47/18639 0.0212765957446809 1.80261121856867 0.428073382755682 0.588600901289062 GO:0043495 protein-membrane adaptor activity 1/220 47/18639 0.0212765957446809 1.80261121856867 0.428073382755682 0.588600901289062 GO:0140359 ABC-type transporter activity 1/220 47/18639 0.0212765957446809 1.80261121856867 0.428073382755682 0.588600901289062 GO:0003714 transcription corepressor activity 3/220 204/18639 0.0147058823529412 1.24592245989305 0.43354448814522 0.592101481880311 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/220 48/18639 0.0208333333333333 1.76505681818182 0.434841016995879 0.592101481880311 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/220 48/18639 0.0208333333333333 1.76505681818182 0.434841016995879 0.592101481880311 GO:0140693 molecular condensate scaffold activity 1/220 48/18639 0.0208333333333333 1.76505681818182 0.434841016995879 0.592101481880311 GO:0016763 pentosyltransferase activity 1/220 49/18639 0.0204081632653061 1.72903525046382 0.441528929225501 0.596861998302424 GO:0035254 glutamate receptor binding 1/220 49/18639 0.0204081632653061 1.72903525046382 0.441528929225501 0.596861998302424 GO:0060590 ATPase regulator activity 1/220 49/18639 0.0204081632653061 1.72903525046382 0.441528929225501 0.596861998302424 GO:0005006 epidermal growth factor receptor activity 1/220 50/18639 0.02 1.69445454545455 0.448138054323424 0.602890763730075 GO:0032813 tumor necrosis factor receptor superfamily binding 1/220 50/18639 0.02 1.69445454545455 0.448138054323424 0.602890763730075 GO:0003743 translation initiation factor activity 1/220 51/18639 0.0196078431372549 1.66122994652406 0.45466931625515 0.60730830099795 GO:0005048 signal sequence binding 1/220 51/18639 0.0196078431372549 1.66122994652406 0.45466931625515 0.60730830099795 GO:0030544 Hsp70 protein binding 1/220 51/18639 0.0196078431372549 1.66122994652406 0.45466931625515 0.60730830099795 GO:0004864 protein phosphatase inhibitor activity 1/220 53/18639 0.0188679245283019 1.59854202401372 0.467501892674583 0.61710249833045 GO:0005246 calcium channel regulator activity 1/220 53/18639 0.0188679245283019 1.59854202401372 0.467501892674583 0.61710249833045 GO:0008146 sulfotransferase activity 1/220 53/18639 0.0188679245283019 1.59854202401372 0.467501892674583 0.61710249833045 GO:0140296 general transcription initiation factor binding 1/220 53/18639 0.0188679245283019 1.59854202401372 0.467501892674583 0.61710249833045 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/220 53/18639 0.0188679245283019 1.59854202401372 0.467501892674583 0.61710249833045 GO:0003925 G protein activity 1/220 54/18639 0.0185185185185185 1.56893939393939 0.473805001660465 0.621038798905422 GO:0050661 NADP binding 1/220 54/18639 0.0185185185185185 1.56893939393939 0.473805001660465 0.621038798905422 GO:0140463 chromatin-protein adaptor activity 1/220 54/18639 0.0185185185185185 1.56893939393939 0.473805001660465 0.621038798905422 GO:0019838 growth factor binding 2/220 136/18639 0.0147058823529412 1.24592245989305 0.478622487306167 0.624435384601767 GO:0140789 histone phosphatase activity 2/220 136/18639 0.0147058823529412 1.24592245989305 0.478622487306167 0.624435384601767 GO:0019212 phosphatase inhibitor activity 1/220 56/18639 0.0178571428571429 1.51290584415584 0.486189269133592 0.631370786999873 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/220 56/18639 0.0178571428571429 1.51290584415584 0.486189269133592 0.631370786999873 GO:0004713 protein tyrosine kinase activity 2/220 140/18639 0.0142857142857143 1.21032467532468 0.49383939530727 0.639824251194869 GO:0045309 protein phosphorylated amino acid binding 1/220 59/18639 0.0169491525423729 1.43597842835131 0.504223711270023 0.648783261519456 GO:0070063 RNA polymerase binding 1/220 59/18639 0.0169491525423729 1.43597842835131 0.504223711270023 0.648783261519456 GO:0070888 E-box binding 1/220 59/18639 0.0169491525423729 1.43597842835131 0.504223711270023 0.648783261519456 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/220 60/18639 0.0166666666666667 1.41204545454545 0.510094044075221 0.654834688160639 GO:0005085 guanyl-nucleotide exchange factor activity 3/220 230/18639 0.0130434782608696 1.1050790513834 0.512086269597473 0.655891317909092 GO:0019905 syntaxin binding 1/220 61/18639 0.0163934426229508 1.38889716840537 0.51589518032063 0.658069534909133 GO:0015293 symporter activity 2/220 146/18639 0.0136986301369863 1.16058530510585 0.516132968556182 0.658069534909133 GO:0019209 kinase activator activity 2/220 148/18639 0.0135135135135135 1.14490171990172 0.523419116084973 0.665846086448231 GO:0008509 monoatomic anion transmembrane transporter activity 2/220 149/18639 0.0134228187919463 1.13721781574131 0.527034609154643 0.667745891569861 GO:0005507 copper ion binding 1/220 63/18639 0.0158730158730159 1.34480519480519 0.527293101542689 0.667745891569861 GO:0005543 phospholipid binding 6/220 497/18639 0.0120724346076459 1.02280958478142 0.535347480961399 0.676418776620146 GO:0019843 rRNA binding 1/220 65/18639 0.0153846153846154 1.30342657342657 0.538423857570304 0.677255121293589 GO:0120013 lipid transfer activity 1/220 65/18639 0.0153846153846154 1.30342657342657 0.538423857570304 0.677255121293589 GO:0003774 cytoskeletal motor activity 2/220 153/18639 0.0130718954248366 1.10748663101604 0.541311049989529 0.679363532537194 GO:0140375 immune receptor activity 2/220 156/18639 0.0128205128205128 1.08618881118881 0.55182187047411 0.691009083339232 GO:0003777 microtubule motor activity 1/220 68/18639 0.0147058823529412 1.24592245989305 0.554632654877324 0.691442043080398 GO:0030145 manganese ion binding 1/220 68/18639 0.0147058823529412 1.24592245989305 0.554632654877324 0.691442043080398 GO:0098960 postsynaptic neurotransmitter receptor activity 1/220 69/18639 0.0144927536231884 1.22786561264822 0.55990866671982 0.696471756163679 GO:0016782 transferase activity, transferring sulphur-containing groups 1/220 70/18639 0.0142857142857143 1.21032467532468 0.565122457421039 0.701401988082307 GO:0004674 protein serine/threonine kinase activity 5/220 433/18639 0.0115473441108545 0.97832248582826 0.582088303969237 0.720864323458591 GO:0031491 nucleosome binding 1/220 74/18639 0.0135135135135135 1.14490171990172 0.58536989087423 0.72333151713754 GO:0016874 ligase activity 2/220 167/18639 0.0119760479041916 1.01464344039194 0.588900701929165 0.726095151169806 GO:0019003 GDP binding 1/220 75/18639 0.0133333333333333 1.12963636363636 0.590283363753717 0.726203875144376 GO:0003730 mRNA 3'-UTR binding 3/220 262/18639 0.0114503816793893 0.970107564191534 0.600276702859993 0.73688234202288 GO:0019199 transmembrane receptor protein kinase activity 1/220 78/18639 0.0128205128205128 1.08618881118881 0.604678711101357 0.739432183235117 GO:0008201 heparin binding 2/220 172/18639 0.0116279069767442 0.98514799154334 0.604989968101459 0.739432183235117 GO:0015370 solute:sodium symporter activity 1/220 79/18639 0.0126582278481013 1.07243958573072 0.609364379091104 0.74270584659986 GO:0016757 glycosyltransferase activity 3/220 267/18639 0.0112359550561798 0.95194075587334 0.61308349714133 0.74270584659986 GO:0000049 tRNA binding 1/220 80/18639 0.0125 1.05903409090909 0.613994758218257 0.74270584659986 GO:0003735 structural constituent of ribosome 2/220 175/18639 0.0114285714285714 0.96825974025974 0.61441361196291 0.74270584659986 GO:0004721 phosphoprotein phosphatase activity 2/220 175/18639 0.0114285714285714 0.96825974025974 0.61441361196291 0.74270584659986 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/220 268/18639 0.0111940298507463 0.948388738127544 0.615611797983841 0.74270584659986 GO:0001618 virus receptor activity 1/220 81/18639 0.0123456790123457 1.0459595959596 0.618570497923628 0.744673925611922 GO:0140272 exogenous protein binding 1/220 82/18639 0.0121951219512195 1.03320399113082 0.623092240054073 0.748511234840118 GO:0030165 PDZ domain binding 1/220 83/18639 0.0120481927710843 1.02075575027382 0.627560618950884 0.752268177844969 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/220 181/18639 0.0110497237569061 0.936162732295329 0.632744873699635 0.755557754569342 GO:1901681 sulfur compound binding 3/220 275/18639 0.0109090909090909 0.924247933884298 0.632998475307648 0.755557754569342 GO:0001217 DNA-binding transcription repressor activity 3/220 278/18639 0.0107913669064748 0.914274035317201 0.64028203533214 0.759842843109912 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/220 86/18639 0.0116279069767442 0.98514799154334 0.640651808896592 0.759842843109912 GO:0050660 flavin adenine dinucleotide binding 1/220 86/18639 0.0116279069767442 0.98514799154334 0.640651808896592 0.759842843109912 GO:1901981 phosphatidylinositol phosphate binding 2/220 185/18639 0.0108108108108108 0.915921375921376 0.64458526054635 0.761676114529719 GO:0008081 phosphoric diester hydrolase activity 1/220 87/18639 0.0114942528735632 0.973824451410658 0.644912931197177 0.761676114529719 GO:0008234 cysteine-type peptidase activity 2/220 187/18639 0.0106951871657754 0.906125425376762 0.650392001337371 0.766533430147616 GO:0019902 phosphatase binding 2/220 190/18639 0.0105263157894737 0.891818181818182 0.658961099068117 0.775004563054956 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/220 91/18639 0.010989010989011 0.931018981018981 0.66146028610227 0.776316360885719 GO:0051219 phosphoprotein binding 1/220 93/18639 0.010752688172043 0.91099706744868 0.669443790584612 0.78404585911893 GO:0042562 hormone binding 1/220 94/18639 0.0106382978723404 0.901305609284333 0.673364979308401 0.786995319566694 GO:0016758 hexosyltransferase activity 2/220 197/18639 0.0101522842639594 0.860129210890632 0.678303544154415 0.791119102433735 GO:0004896 cytokine receptor activity 1/220 96/18639 0.0104166666666667 0.882528409090909 0.68106898383652 0.792696472888564 GO:0030594 neurotransmitter receptor activity 1/220 97/18639 0.0103092783505155 0.873430178069353 0.684852881995177 0.795450241820485 GO:0042626 ATPase-coupled transmembrane transporter activity 1/220 98/18639 0.0102040816326531 0.864517625231911 0.688592088443298 0.79814082978655 GO:0008238 exopeptidase activity 1/220 102/18639 0.00980392156862745 0.830614973262032 0.703112414762042 0.813290855013413 GO:0000149 SNARE binding 1/220 106/18639 0.00943396226415094 0.799271012006861 0.716958621505681 0.827600384083719 GO:1902936 phosphatidylinositol bisphosphate binding 1/220 111/18639 0.00900900900900901 0.763267813267813 0.733365732630927 0.844801182763758 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/220 122/18639 0.00819672131147541 0.694448584202683 0.766204340221206 0.862363395137924 GO:0042826 histone deacetylase binding 1/220 127/18639 0.0078740157480315 0.667108088761632 0.77976824906994 0.862363395137924 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/220 243/18639 0.00823045267489712 0.697306397306397 0.784068532792253 0.862363395137924 GO:0035591 signaling adaptor activity 1/220 129/18639 0.00775193798449612 0.65676532769556 0.784971833573682 0.862363395137924 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/220 130/18639 0.00769230769230769 0.651713286713287 0.787527543817539 0.862363395137924 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/220 130/18639 0.00769230769230769 0.651713286713287 0.787527543817539 0.862363395137924 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0004711 ribosomal protein S6 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0035175 histone H3S10 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0035979 histone H2AXS139 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0044022 histone H3S28 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0044023 histone H4S1 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0044024 histone H2AS1 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0044025 histone H2BS14 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0072354 histone H3T3 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0072371 histone H2AS121 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0140823 histone H2BS36 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0140855 histone H3S57 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0140995 histone H2A kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0140997 histone H4 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0140998 histone H2B kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:1990244 histone H2AT120 kinase activity 2/220 245/18639 0.00816326530612245 0.691614100185529 0.787890302457193 0.862363395137924 GO:0004677 DNA-dependent protein kinase activity 2/220 246/18639 0.00813008130081301 0.68880266075388 0.789778870217145 0.862363395137924 GO:0140857 histone H3T45 kinase activity 2/220 246/18639 0.00813008130081301 0.68880266075388 0.789778870217145 0.862363395137924 GO:0035402 histone H3T11 kinase activity 2/220 247/18639 0.00809716599190283 0.686013986013986 0.791652671115919 0.862363395137924 GO:0035403 histone H3T6 kinase activity 2/220 247/18639 0.00809716599190283 0.686013986013986 0.791652671115919 0.862363395137924 GO:0042393 histone binding 2/220 247/18639 0.00809716599190283 0.686013986013986 0.791652671115919 0.862363395137924 GO:0004679 AMP-activated protein kinase activity 2/220 248/18639 0.00806451612903226 0.68324780058651 0.793511788682716 0.86271339816086 GO:0106310 protein serine kinase activity 3/220 361/18639 0.00831024930747922 0.704066985645933 0.802228323867932 0.870503074835416 GO:0042578 phosphoric ester hydrolase activity 3/220 363/18639 0.00826446280991736 0.700187828700225 0.805238306820743 0.871337491384527 GO:0003713 transcription coactivator activity 2/220 256/18639 0.0078125 0.661896306818182 0.807866177586502 0.871337491384527 GO:0030295 protein kinase activator activity 1/220 139/18639 0.00719424460431655 0.609516023544801 0.809210041018429 0.871337491384527 GO:0140767 enzyme-substrate adaptor activity 1/220 139/18639 0.00719424460431655 0.609516023544801 0.809210041018429 0.871337491384527 GO:0019903 protein phosphatase binding 1/220 144/18639 0.00694444444444444 0.588352272727273 0.820288858040221 0.879889195718095 GO:0019955 cytokine binding 1/220 144/18639 0.00694444444444444 0.588352272727273 0.820288858040221 0.879889195718095 GO:0008194 UDP-glycosyltransferase activity 1/220 145/18639 0.00689655172413793 0.584294670846395 0.822426541264397 0.880498644368945 GO:0019842 vitamin binding 1/220 150/18639 0.00666666666666667 0.564818181818182 0.832741166841096 0.88191608844719 GO:0000510 H3-H4 histone complex chaperone activity 1/220 151/18639 0.00662251655629139 0.561077664057796 0.834731374169505 0.88191608844719 GO:0140584 chromatin extrusion motor activity 1/220 151/18639 0.00662251655629139 0.561077664057796 0.834731374169505 0.88191608844719 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/220 151/18639 0.00662251655629139 0.561077664057796 0.834731374169505 0.88191608844719 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/220 151/18639 0.00662251655629139 0.561077664057796 0.834731374169505 0.88191608844719 GO:0016791 phosphatase activity 2/220 273/18639 0.00732600732600733 0.620679320679321 0.835462649667158 0.88191608844719 GO:0015616 DNA translocase activity 1/220 152/18639 0.00657894736842105 0.557386363636364 0.836698006454377 0.88191608844719 GO:0140674 ATP-dependent histone chaperone activity 1/220 152/18639 0.00657894736842105 0.557386363636364 0.836698006454377 0.88191608844719 GO:0061775 cohesin loader activity 1/220 153/18639 0.0065359477124183 0.553743315508021 0.838641341694277 0.88191608844719 GO:0003712 transcription coregulator activity 4/220 495/18639 0.00808080808080808 0.684628099173554 0.83947092911016 0.88191608844719 GO:0140658 ATP-dependent chromatin remodeler activity 1/220 158/18639 0.00632911392405063 0.536219792865362 0.848018065859823 0.889230158780113 GO:0035091 phosphatidylinositol binding 2/220 284/18639 0.00704225352112676 0.596638924455826 0.851366307070758 0.889676054910779 GO:0003689 DNA clamp loader activity 1/220 160/18639 0.00625 0.529517045454545 0.851615047214061 0.889676054910779 GO:0015081 sodium ion transmembrane transporter activity 1/220 164/18639 0.00609756097560976 0.51660199556541 0.858556740400529 0.893599872661775 GO:0140713 histone chaperone activity 1/220 164/18639 0.00609756097560976 0.51660199556541 0.858556740400529 0.893599872661775 GO:0140030 modification-dependent protein binding 1/220 173/18639 0.00578034682080925 0.489726747241198 0.873016127734633 0.906966754924313 GO:0004252 serine-type endopeptidase activity 1/220 176/18639 0.00568181818181818 0.481379132231405 0.877501087421069 0.909941053684325 GO:0016853 isomerase activity 1/220 180/18639 0.00555555555555556 0.470681818181818 0.883236666556805 0.914198837524664 GO:0008236 serine-type peptidase activity 1/220 194/18639 0.00515463917525773 0.436715089034677 0.901285580302259 0.931162450367527 GO:0017171 serine hydrolase activity 1/220 198/18639 0.00505050505050505 0.427892561983471 0.905911964469308 0.934221713358974 GO:0008094 ATP-dependent activity, acting on DNA 1/220 210/18639 0.00476190476190476 0.403441558441558 0.91853547876133 0.945501657954324 GO:0141003 histone H2AX kinase activity 2/220 354/18639 0.00564971751412429 0.478659476117103 0.923769386015135 0.949147665850715 GO:0140996 histone H3 kinase activity 2/220 357/18639 0.00560224089635854 0.474637127578304 0.92597244297673 0.949671920493502 GO:0035173 histone kinase activity 2/220 360/18639 0.00555555555555556 0.470681818181818 0.92811558596158 0.950132926504464 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/220 229/18639 0.00436681222707424 0.369968241365621 0.935163138971026 0.953107434513545 GO:0000287 magnesium ion binding 1/220 230/18639 0.00434782608695652 0.368359683794466 0.935937941221237 0.953107434513545 GO:0061659 ubiquitin-like protein ligase activity 2/220 372/18639 0.00537634408602151 0.45549853372434 0.936117997178188 0.953107434513545 GO:0046873 metal ion transmembrane transporter activity 2/220 450/18639 0.00444444444444444 0.376545454545455 0.970859603286178 0.986688835948453 GO:0019787 ubiquitin-like protein transferase activity 2/220 479/18639 0.00417536534446764 0.353748339343329 0.978383861529151 0.989517299666881 GO:0030371 translation repressor activity 1/220 329/18639 0.00303951367781155 0.257515888366952 0.980577926171839 0.989517299666881 GO:0016755 aminoacyltransferase activity 2/220 496/18639 0.00403225806451613 0.341623900293255 0.98188329786966 0.989517299666881 GO:0140097 catalytic activity, acting on DNA 1/220 336/18639 0.00297619047619048 0.252150974025974 0.982153991334432 0.989517299666881 GO:0005261 monoatomic cation channel activity 1/220 341/18639 0.00293255131964809 0.248453745667822 0.983201162649005 0.989517299666881 GO:0061630 ubiquitin protein ligase activity 1/220 353/18639 0.0028328611898017 0.240007725985063 0.985471483883359 0.989517299666881 GO:0045182 translation regulator activity 1/220 356/18639 0.00280898876404494 0.237985188968335 0.985989608758978 0.989517299666881 GO:0005216 monoatomic ion channel activity 1/220 448/18639 0.00223214285714286 0.189113230519481 0.995412902209985 0.995468378077931 GO:0004842 ubiquitin-protein transferase activity 1/220 449/18639 0.0022271714922049 0.188692042923669 0.995468378077931 0.995468378077931