ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030695 GTPase regulator activity 20/215 489/18639 0.0408997955010225 3.54572692252818 1.05740073223666e-06 0.000322475311729699 GO:0060589 nucleoside-triphosphatase regulator activity 20/215 490/18639 0.0408163265306122 3.53849074513526 1.09128701092961e-06 0.000322475311729699 GO:0005131 growth hormone receptor binding 4/215 10/18639 0.4 34.6772093023256 3.42409090319637e-06 0.000605473103015958 GO:0003779 actin binding 18/215 443/18639 0.0406320541760722 3.52251561761772 4.09795670399972e-06 0.000605473103015958 GO:0005096 GTPase activator activity 13/215 271/18639 0.0479704797047971 4.15870591264052 1.66682660492253e-05 0.00197018904701842 GO:0005179 hormone activity 8/215 132/18639 0.0606060606060606 5.25412262156448 0.000148956139968325 0.01467217978688 GO:0045296 cadherin binding 12/215 334/18639 0.0359281437125748 3.11471939841248 0.000523301355409012 0.044181585863818 GO:0051427 hormone receptor binding 4/215 34/18639 0.117647058823529 10.1991792065663 0.00060862337261893 0.0449620516522235 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/215 484/18639 0.0289256198347107 2.50764943301941 0.00152860766023709 0.0938439454004815 GO:0004222 metalloendopeptidase activity 6/215 110/18639 0.0545454545454545 4.72871035940803 0.0017384619845518 0.0938439454004815 GO:0001216 DNA-binding transcription activator activity 14/215 491/18639 0.0285132382892057 2.47189883010468 0.00174667241862148 0.0938439454004815 GO:0008083 growth factor activity 7/215 162/18639 0.0432098765432099 3.74599483204134 0.00278284838399746 0.136580310074944 GO:0030159 signaling receptor complex adaptor activity 4/215 52/18639 0.0769230769230769 6.66869409660107 0.00302286989913538 0.136580310074944 GO:0004435 phosphatidylinositol phospholipase C activity 3/215 26/18639 0.115384615384615 10.0030411449016 0.00323540497639462 0.136580310074944 GO:0035255 ionotropic glutamate receptor binding 3/215 27/18639 0.111111111111111 9.63255813953488 0.00360916475173059 0.142201091218185 GO:0004629 phospholipase C activity 3/215 29/18639 0.103448275862069 8.9682437850842 0.00443309176026869 0.163747326894925 GO:0005543 phospholipid binding 13/215 497/18639 0.0261569416498994 2.2676243507557 0.00522298314355284 0.174417283620611 GO:0008237 metallopeptidase activity 7/215 184/18639 0.0380434782608696 3.29810414560162 0.00558285063892694 0.174417283620611 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/215 10/18639 0.2 17.3386046511628 0.0056073238389029 0.174417283620611 GO:0019206 nucleoside kinase activity 2/215 11/18639 0.181818181818182 15.7623678646934 0.00680156460975951 0.195874583805997 GO:0090482 vitamin transmembrane transporter activity 3/215 34/18639 0.0882352941176471 7.64938440492476 0.00696001059209127 0.195874583805997 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/215 12/18639 0.166666666666667 14.4488372093023 0.00810020848859015 0.208414621368566 GO:0071933 Arp2/3 complex binding 2/215 14/18639 0.142857142857143 12.3847176079734 0.0110005715663585 0.208414621368566 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/215 41/18639 0.0731707317073171 6.34339194554736 0.0116900640671811 0.208414621368566 GO:0004674 protein serine/threonine kinase activity 11/215 433/18639 0.0254041570438799 2.20236317739943 0.0120686244413699 0.208414621368566 GO:0004559 alpha-mannosidase activity 2/215 15/18639 0.133333333333333 11.5590697674419 0.0125973339276524 0.208414621368566 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/215 15/18639 0.133333333333333 11.5590697674419 0.0125973339276524 0.208414621368566 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/215 15/18639 0.133333333333333 11.5590697674419 0.0125973339276524 0.208414621368566 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/215 16/18639 0.125 10.8366279069767 0.0142885843783255 0.208414621368566 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/215 16/18639 0.125 10.8366279069767 0.0142885843783255 0.208414621368566 GO:0015923 mannosidase activity 2/215 16/18639 0.125 10.8366279069767 0.0142885843783255 0.208414621368566 GO:0008017 microtubule binding 8/215 276/18639 0.0289855072463768 2.51284125379171 0.0150329985559014 0.208414621368566 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/215 17/18639 0.117647058823529 10.1991792065663 0.0160719516580344 0.208414621368566 GO:0035591 signaling adaptor activity 5/215 129/18639 0.0387596899224806 3.36019469983775 0.016957650163504 0.208414621368566 GO:0005085 guanyl-nucleotide exchange factor activity 7/215 230/18639 0.0304347826086957 2.63848331648129 0.0175743194881679 0.208414621368566 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/215 18/18639 0.111111111111111 9.63255813953488 0.0179451061939554 0.208414621368566 GO:0008081 phosphoric diester hydrolase activity 4/215 87/18639 0.0459770114942529 3.98588612670409 0.0182124956971923 0.208414621368566 GO:0035254 glutamate receptor binding 3/215 49/18639 0.0612244897959184 5.30773611770289 0.0188956993052553 0.208414621368566 GO:0015245 fatty acid transmembrane transporter activity 2/215 19/18639 0.105263157894737 9.12558139534884 0.0199057594619299 0.208414621368566 GO:1901981 phosphatidylinositol phosphate binding 6/215 185/18639 0.0324324324324324 2.81166561910748 0.0205681558454977 0.208414621368566 GO:0046943 carboxylic acid transmembrane transporter activity 6/215 188/18639 0.0319148936170213 2.76679861454725 0.0220569482799695 0.208414621368566 GO:0005342 organic acid transmembrane transporter activity 6/215 189/18639 0.0317460317460317 2.75215946843854 0.0225689608659433 0.208414621368566 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/215 243/18639 0.0288065843621399 2.49732988802756 0.0229438020581335 0.208414621368566 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0004711 ribosomal protein S6 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0035175 histone H3S10 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0035979 histone H2AXS139 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0044022 histone H3S28 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0044023 histone H4S1 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0044024 histone H2AS1 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0044025 histone H2BS14 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0072354 histone H3T3 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0072371 histone H2AS121 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0140823 histone H2BS36 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0140855 histone H3S57 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0140995 histone H2A kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0140997 histone H4 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0140998 histone H2B kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:1990244 histone H2AT120 kinase activity 7/215 245/18639 0.0285714285714286 2.47694352159468 0.0238602085097097 0.208414621368566 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/215 21/18639 0.0952380952380952 8.25647840531562 0.0240806095710569 0.208414621368566 GO:0008373 sialyltransferase activity 2/215 21/18639 0.0952380952380952 8.25647840531562 0.0240806095710569 0.208414621368566 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/215 21/18639 0.0952380952380952 8.25647840531562 0.0240806095710569 0.208414621368566 GO:0051010 microtubule plus-end binding 2/215 21/18639 0.0952380952380952 8.25647840531562 0.0240806095710569 0.208414621368566 GO:0061891 calcium ion sensor activity 2/215 21/18639 0.0952380952380952 8.25647840531562 0.0240806095710569 0.208414621368566 GO:0004677 DNA-dependent protein kinase activity 7/215 246/18639 0.0284552845528455 2.46687464549064 0.0243277438788193 0.208414621368566 GO:0140857 histone H3T45 kinase activity 7/215 246/18639 0.0284552845528455 2.46687464549064 0.0243277438788193 0.208414621368566 GO:0106310 protein serine kinase activity 9/215 361/18639 0.0249307479224377 2.16132190942472 0.0246173725001763 0.208414621368566 GO:0035402 histone H3T11 kinase activity 7/215 247/18639 0.0283400809716599 2.45688729874776 0.0248015482584443 0.208414621368566 GO:0035403 histone H3T6 kinase activity 7/215 247/18639 0.0283400809716599 2.45688729874776 0.0248015482584443 0.208414621368566 GO:0004679 AMP-activated protein kinase activity 7/215 248/18639 0.0282258064516129 2.44698049512378 0.0252816568148565 0.208414621368566 GO:0042578 phosphoric ester hydrolase activity 9/215 363/18639 0.0247933884297521 2.14941379973092 0.0253906137707897 0.208414621368566 GO:0140517 protein-RNA adaptor activity 2/215 22/18639 0.0909090909090909 7.88118393234672 0.0262904289839451 0.20996815580421 GO:0140784 metal ion sensor activity 2/215 22/18639 0.0909090909090909 7.88118393234672 0.0262904289839451 0.20996815580421 GO:0170055 lipid transmembrane transporter activity 3/215 56/18639 0.0535714285714286 4.64426910299003 0.0268189350515551 0.211333208206254 GO:0030215 semaphorin receptor binding 2/215 24/18639 0.0833333333333333 7.22441860465116 0.0309442032405731 0.237506806690633 GO:0048027 mRNA 5'-UTR binding 2/215 24/18639 0.0833333333333333 7.22441860465116 0.0309442032405731 0.237506806690633 GO:0004497 monooxygenase activity 4/215 106/18639 0.0377358490566038 3.27143483984204 0.0343985031721958 0.259034448049038 GO:0015179 L-amino acid transmembrane transporter activity 3/215 62/18639 0.0483870967741935 4.19482370592648 0.0348132284312263 0.259034448049038 GO:0015631 tubulin binding 9/215 385/18639 0.0233766233766234 2.02659015403201 0.0350638846766887 0.259034448049038 GO:0070412 R-SMAD binding 2/215 26/18639 0.0769230769230769 6.66869409660107 0.0358963941704253 0.261910727836066 GO:0008395 steroid hydroxylase activity 2/215 27/18639 0.0740740740740741 6.42170542635659 0.0384793725239209 0.277333038556552 GO:0045499 chemorepellent activity 2/215 28/18639 0.0714285714285714 6.19235880398671 0.0411309990708986 0.289385957748822 GO:0097718 disordered domain specific binding 2/215 28/18639 0.0714285714285714 6.19235880398671 0.0411309990708986 0.289385957748822 GO:0003785 actin monomer binding 2/215 29/18639 0.0689655172413793 5.97882919005613 0.0438493625753896 0.30133689862855 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/215 29/18639 0.0689655172413793 5.97882919005613 0.0438493625753896 0.30133689862855 GO:0016247 channel regulator activity 5/215 168/18639 0.0297619047619048 2.58014950166113 0.0454265342628849 0.308587146544425 GO:0035091 phosphatidylinositol binding 7/215 284/18639 0.0246478873239437 2.13679986898133 0.0470232693448075 0.311055644426304 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/215 70/18639 0.0428571428571429 3.71541528239203 0.0471649707534165 0.311055644426304 GO:0141108 transporter regulator activity 5/215 170/18639 0.0294117647058824 2.54979480164159 0.0473688798618737 0.311055644426304 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 8/215 349/18639 0.0229226361031519 1.9872326247751 0.0499450123791511 0.324368157319542 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/215 32/18639 0.0625 5.41831395348837 0.0523862781726805 0.336524895652763 GO:0141003 histone H2AX kinase activity 8/215 354/18639 0.0225988700564972 1.95916436736303 0.0534306869913678 0.339543397977402 GO:0071889 14-3-3 protein binding 2/215 33/18639 0.0606060606060606 5.25412262156448 0.0553531610178389 0.345012401553939 GO:0140996 histone H3 kinase activity 8/215 357/18639 0.0224089635854342 1.94270080125073 0.0555953975433356 0.345012401553939 GO:0098631 cell adhesion mediator activity 3/215 76/18639 0.0394736842105263 3.42209302325581 0.057654724044615 0.345012401553939 GO:0035173 histone kinase activity 8/215 360/18639 0.0222222222222222 1.92651162790698 0.0578154539788529 0.345012401553939 GO:0008376 acetylgalactosaminyltransferase activity 2/215 34/18639 0.0588235294117647 5.09958960328317 0.0583777329194482 0.345012401553939 GO:0015020 glucuronosyltransferase activity 2/215 34/18639 0.0588235294117647 5.09958960328317 0.0583777329194482 0.345012401553939 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/215 34/18639 0.0588235294117647 5.09958960328317 0.0583777329194482 0.345012401553939 GO:0005343 organic acid:sodium symporter activity 2/215 35/18639 0.0571428571428571 4.95388704318937 0.061458282296187 0.35609651801026 GO:0016229 steroid dehydrogenase activity 2/215 35/18639 0.0571428571428571 4.95388704318937 0.061458282296187 0.35609651801026 GO:0015370 solute:sodium symporter activity 3/215 79/18639 0.0379746835443038 3.2921401236385 0.0632782232484973 0.363081844076329 GO:0015101 organic cation transmembrane transporter activity 3/215 81/18639 0.037037037037037 3.21085271317829 0.0671631812628641 0.381667693522622 GO:0051117 ATPase binding 3/215 84/18639 0.0357142857142857 3.09617940199336 0.0731895135689009 0.408195175823049 GO:0051020 GTPase binding 7/215 315/18639 0.0222222222222222 1.92651162790698 0.0732126711290071 0.408195175823049 GO:0003713 transcription coactivator activity 6/215 256/18639 0.0234375 2.03186773255814 0.0767058019009322 0.420981566258467 GO:0050660 flavin adenine dinucleotide binding 3/215 86/18639 0.0348837209302326 3.02417522985398 0.0773365863781852 0.420981566258467 GO:0071949 FAD binding 2/215 40/18639 0.05 4.3346511627907 0.077642962304861 0.420981566258467 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/215 41/18639 0.0487804878048781 4.22892796369824 0.0810251622144856 0.435326098806918 GO:0020037 heme binding 4/215 142/18639 0.028169014084507 2.44205699312152 0.0822592170014096 0.437974749980478 GO:0035198 miRNA binding 2/215 42/18639 0.0476190476190476 4.12823920265781 0.084452212917352 0.445636230662099 GO:0043178 alcohol binding 3/215 92/18639 0.0326086956521739 2.82694641051567 0.0903751148551204 0.446695726119708 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/215 268/18639 0.0223880597014925 1.94088858035404 0.090740431505942 0.446695726119708 GO:0001046 core promoter sequence-specific DNA binding 2/215 44/18639 0.0454545454545455 3.94059196617336 0.091435001892844 0.446695726119708 GO:0016248 channel inhibitor activity 2/215 44/18639 0.0454545454545455 3.94059196617336 0.091435001892844 0.446695726119708 GO:0019205 nucleobase-containing compound kinase activity 2/215 44/18639 0.0454545454545455 3.94059196617336 0.091435001892844 0.446695726119708 GO:0008514 organic anion transmembrane transporter activity 6/215 269/18639 0.0223048327137546 1.93367338117057 0.0919692373682862 0.446695726119708 GO:0005516 calmodulin binding 5/215 207/18639 0.0241545893719807 2.09403437815976 0.092045634726912 0.446695726119708 GO:0051015 actin filament binding 5/215 209/18639 0.0239234449760766 2.07399577167019 0.0949234024547412 0.446695726119708 GO:0141110 transporter inhibitor activity 2/215 45/18639 0.0444444444444444 3.85302325581395 0.0949878766518902 0.446695726119708 GO:0019842 vitamin binding 4/215 150/18639 0.0266666666666667 2.31181395348837 0.0958435362064507 0.446695726119708 GO:0004175 endopeptidase activity 8/215 405/18639 0.0197530864197531 1.71245478036176 0.0978632706832471 0.446695726119708 GO:0030291 protein serine/threonine kinase inhibitor activity 2/215 46/18639 0.0434782608695652 3.76926188068756 0.0985798743057905 0.446695726119708 GO:0046906 tetrapyrrole binding 4/215 152/18639 0.0263157894736842 2.28139534883721 0.0993952703219044 0.446695726119708 GO:0001784 phosphotyrosine residue binding 2/215 47/18639 0.0425531914893617 3.68906481939634 0.102209630039931 0.446695726119708 GO:0001217 DNA-binding transcription repressor activity 6/215 278/18639 0.0215827338129496 1.87107244437009 0.103431940452081 0.446695726119708 GO:0032266 phosphatidylinositol-3-phosphate binding 2/215 48/18639 0.0416666666666667 3.61220930232558 0.105875805054401 0.446695726119708 GO:0140693 molecular condensate scaffold activity 2/215 48/18639 0.0416666666666667 3.61220930232558 0.105875805054401 0.446695726119708 GO:0004382 GDP phosphatase activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0015187 glycine transmembrane transporter activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0070513 death domain binding 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0140999 histone H3K4 trimethyltransferase activity 1/215 10/18639 0.1 8.6693023255814 0.109567657111276 0.446695726119708 GO:0031267 small GTPase binding 6/215 283/18639 0.0212014134275618 1.83801462733174 0.110109397645723 0.446695726119708 GO:0140297 DNA-binding transcription factor binding 9/215 488/18639 0.0184426229508197 1.59884674037362 0.112838526303251 0.446695726119708 GO:0015171 amino acid transmembrane transporter activity 3/215 102/18639 0.0294117647058824 2.54979480164159 0.113956144020506 0.446695726119708 GO:0099106 ion channel regulator activity 4/215 160/18639 0.025 2.16732558139535 0.114198831138889 0.446695726119708 GO:0004722 protein serine/threonine phosphatase activity 3/215 103/18639 0.029126213592233 2.52503951230526 0.116431944556093 0.446695726119708 GO:0005010 insulin-like growth factor receptor activity 2/215 51/18639 0.0392156862745098 3.39972640218878 0.117079839351707 0.446695726119708 GO:0000099 sulfur amino acid transmembrane transporter activity 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0008503 benzodiazepine receptor activity 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0015173 aromatic amino acid transmembrane transporter activity 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0034056 estrogen response element binding 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0042608 T cell receptor binding 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0070697 activin receptor binding 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0070990 snRNP binding 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0097493 structural molecule activity conferring elasticity 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0140537 transcription regulator activator activity 1/215 11/18639 0.0909090909090909 7.88118393234672 0.119844266361428 0.446695726119708 GO:0005080 protein kinase C binding 2/215 52/18639 0.0384615384615385 3.33434704830054 0.120878809422294 0.446695726119708 GO:0008013 beta-catenin binding 3/215 106/18639 0.0283018867924528 2.45357612988153 0.123978971703763 0.446695726119708 GO:0005246 calcium channel regulator activity 2/215 53/18639 0.0377358490566038 3.27143483984204 0.124707880717119 0.446695726119708 GO:0005544 calcium-dependent phospholipid binding 2/215 53/18639 0.0377358490566038 3.27143483984204 0.124707880717119 0.446695726119708 GO:0140463 chromatin-protein adaptor activity 2/215 54/18639 0.037037037037037 3.21085271317829 0.128565862040623 0.446695726119708 GO:0003995 acyl-CoA dehydrogenase activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0004859 phospholipase inhibitor activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0005095 GTPase inhibitor activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0008179 adenylate cyclase binding 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0008603 cAMP-dependent protein kinase regulator activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0016208 AMP binding 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0016840 carbon-nitrogen lyase activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0035259 nuclear glucocorticoid receptor binding 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0035497 cAMP response element binding 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0070679 inositol 1,4,5 trisphosphate binding 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:1990817 poly(A) RNA polymerase activity 1/215 12/18639 0.0833333333333333 7.22441860465116 0.13000281707714 0.446695726119708 GO:0004620 phospholipase activity 3/215 109/18639 0.0275229357798165 2.38604651162791 0.131698764537151 0.449907340124026 GO:0030170 pyridoxal phosphate binding 2/215 56/18639 0.0357142857142857 3.09617940199336 0.136363905822936 0.457979434706992 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/215 13/18639 0.0769230769230769 6.66869409660107 0.140044659259371 0.457979434706992 GO:0043560 insulin receptor substrate binding 1/215 13/18639 0.0769230769230769 6.66869409660107 0.140044659259371 0.457979434706992 GO:0045159 myosin II binding 1/215 13/18639 0.0769230769230769 6.66869409660107 0.140044659259371 0.457979434706992 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/215 13/18639 0.0769230769230769 6.66869409660107 0.140044659259371 0.457979434706992 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/215 13/18639 0.0769230769230769 6.66869409660107 0.140044659259371 0.457979434706992 GO:0140333 glycerophospholipid flippase activity 1/215 13/18639 0.0769230769230769 6.66869409660107 0.140044659259371 0.457979434706992 GO:0070279 vitamin B6 binding 2/215 57/18639 0.0350877192982456 3.04186046511628 0.140301700607162 0.457979434706992 GO:0061980 regulatory RNA binding 2/215 58/18639 0.0344827586206897 2.98941459502807 0.144263869340261 0.457979434706992 GO:0017124 SH3 domain binding 3/215 115/18639 0.0260869565217391 2.26155712841254 0.14762215991716 0.457979434706992 GO:0015459 potassium channel regulator activity 2/215 59/18639 0.0338983050847458 2.93874655104454 0.148249333351126 0.457979434706992 GO:0045309 protein phosphorylated amino acid binding 2/215 59/18639 0.0338983050847458 2.93874655104454 0.148249333351126 0.457979434706992 GO:0004065 arylsulfatase activity 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0005545 1-phosphatidylinositol binding 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0032036 myosin heavy chain binding 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0034236 protein kinase A catalytic subunit binding 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0043176 amine binding 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0044548 S100 protein binding 1/215 14/18639 0.0714285714285714 6.19235880398671 0.149971127543449 0.457979434706992 GO:0009055 electron transfer activity 3/215 116/18639 0.0258620689655172 2.24206094627105 0.150335042864901 0.457979434706992 GO:0015294 solute:monoatomic cation symporter activity 3/215 116/18639 0.0258620689655172 2.24206094627105 0.150335042864901 0.457979434706992 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/215 60/18639 0.0333333333333333 2.88976744186047 0.152257035396118 0.459101571015845 GO:0098531 ligand-modulated transcription factor activity 2/215 60/18639 0.0333333333333333 2.88976744186047 0.152257035396118 0.459101571015845 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/215 181/18639 0.0220994475138122 1.91586791725556 0.157210433410392 0.469811308216572 GO:0005523 tropomyosin binding 1/215 15/18639 0.0666666666666667 5.77953488372093 0.159783541373149 0.469811308216572 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/215 15/18639 0.0666666666666667 5.77953488372093 0.159783541373149 0.469811308216572 GO:0031005 filamin binding 1/215 15/18639 0.0666666666666667 5.77953488372093 0.159783541373149 0.469811308216572 GO:0140161 monocarboxylate:sodium symporter activity 1/215 15/18639 0.0666666666666667 5.77953488372093 0.159783541373149 0.469811308216572 GO:1901682 sulfur compound transmembrane transporter activity 2/215 63/18639 0.0317460317460317 2.75215946843854 0.164403311461751 0.470256217169611 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/215 122/18639 0.0245901639344262 2.13179565383149 0.166937201757216 0.470256217169611 GO:0044389 ubiquitin-like protein ligase binding 6/215 322/18639 0.0186335403726708 1.6153979488661 0.169243960533424 0.470256217169611 GO:0000062 fatty-acyl-CoA binding 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0005521 lamin binding 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0016722 oxidoreductase activity, acting on metal ions 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0019841 retinol binding 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0022858 alanine transmembrane transporter activity 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0055102 lipase inhibitor activity 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0140327 flippase activity 1/215 16/18639 0.0625 5.41831395348837 0.169483205172804 0.470256217169611 GO:0038024 cargo receptor activity 2/215 65/18639 0.0307692307692308 2.66747763864043 0.172593569241657 0.476648595429061 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/215 17/18639 0.0588235294117647 5.09958960328317 0.179071408517477 0.481050920153768 GO:0008484 sulfuric ester hydrolase activity 1/215 17/18639 0.0588235294117647 5.09958960328317 0.179071408517477 0.481050920153768 GO:0017110 nucleoside diphosphate phosphatase activity 1/215 17/18639 0.0588235294117647 5.09958960328317 0.179071408517477 0.481050920153768 GO:0030169 low-density lipoprotein particle binding 1/215 17/18639 0.0588235294117647 5.09958960328317 0.179071408517477 0.481050920153768 GO:0038191 neuropilin binding 1/215 17/18639 0.0588235294117647 5.09958960328317 0.179071408517477 0.481050920153768 GO:1901567 fatty acid derivative binding 1/215 17/18639 0.0588235294117647 5.09958960328317 0.179071408517477 0.481050920153768 GO:0008409 5'-3' exonuclease activity 1/215 18/18639 0.0555555555555556 4.81627906976744 0.188549426301214 0.487499540392301 GO:0017075 syntaxin-1 binding 1/215 18/18639 0.0555555555555556 4.81627906976744 0.188549426301214 0.487499540392301 GO:0022851 GABA-gated chloride ion channel activity 1/215 18/18639 0.0555555555555556 4.81627906976744 0.188549426301214 0.487499540392301 GO:0031690 adrenergic receptor binding 1/215 18/18639 0.0555555555555556 4.81627906976744 0.188549426301214 0.487499540392301 GO:0050811 GABA receptor binding 1/215 18/18639 0.0555555555555556 4.81627906976744 0.188549426301214 0.487499540392301 GO:0008080 N-acetyltransferase activity 2/215 69/18639 0.0289855072463768 2.51284125379171 0.189162788864631 0.487499540392301 GO:0016298 lipase activity 3/215 130/18639 0.0230769230769231 2.00060822898032 0.189851252956511 0.487499540392301 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/215 132/18639 0.0227272727272727 1.97029598308668 0.195702034422114 0.487499540392301 GO:0016757 glycosyltransferase activity 5/215 267/18639 0.0187265917602996 1.62346485497779 0.196231995591664 0.487499540392301 GO:0140299 molecular sensor activity 2/215 71/18639 0.028169014084507 2.44205699312152 0.197527528594119 0.487499540392301 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0004890 GABA-A receptor activity 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0016918 retinal binding 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0042800 histone H3K4 methyltransferase activity 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0120227 acyl-CoA binding 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0140036 ubiquitin-modified protein reader activity 1/215 19/18639 0.0526315789473684 4.56279069767442 0.197918518903396 0.487499540392301 GO:0004857 enzyme inhibitor activity 7/215 416/18639 0.0168269230769231 1.45877683363148 0.206079662344118 0.487499540392301 GO:0015095 magnesium ion transmembrane transporter activity 1/215 20/18639 0.05 4.3346511627907 0.207179932353222 0.487499540392301 GO:0016408 C-acyltransferase activity 1/215 20/18639 0.05 4.3346511627907 0.207179932353222 0.487499540392301 GO:0031418 L-ascorbic acid binding 1/215 20/18639 0.05 4.3346511627907 0.207179932353222 0.487499540392301 GO:0140789 histone phosphatase activity 3/215 136/18639 0.0220588235294118 1.91234610123119 0.207533202836309 0.487499540392301 GO:0016791 phosphatase activity 5/215 273/18639 0.0183150183150183 1.58778430871454 0.208370166753574 0.487499540392301 GO:0048029 monosaccharide binding 2/215 74/18639 0.027027027027027 2.34305468258957 0.210155918457019 0.487499540392301 GO:0016922 nuclear receptor binding 3/215 137/18639 0.0218978102189781 1.89838737056527 0.210516245379498 0.487499540392301 GO:0010314 phosphatidylinositol-5-phosphate binding 1/215 21/18639 0.0476190476190476 4.12823920265781 0.216334898492331 0.487499540392301 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/215 21/18639 0.0476190476190476 4.12823920265781 0.216334898492331 0.487499540392301 GO:0004713 protein tyrosine kinase activity 3/215 140/18639 0.0214285714285714 1.85770764119601 0.21952123837762 0.487499540392301 GO:0008093 cytoskeletal anchor activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0032931 histone H3K56 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0043992 histone H3K9 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0043993 histone H3K18 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0043994 histone H3K23 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0043999 histone H2AK5 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0044012 histone H2AK9 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0044014 histone H2BK5 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0044015 histone H2BK12 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0044016 histone H3K4 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0044017 histone H3K27 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0044018 histone H3K36 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0046972 histone H4K16 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0050321 tau-protein kinase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0070034 telomerase RNA binding 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0140035 ubiquitin-like protein reader activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0140908 histone H3K122 acetyltransferase activity 1/215 22/18639 0.0454545454545455 3.94059196617336 0.225384635135587 0.487499540392301 GO:0019199 transmembrane receptor protein kinase activity 2/215 78/18639 0.0256410256410256 2.22289803220036 0.227112594094031 0.487499540392301 GO:0046332 SMAD binding 2/215 79/18639 0.0253164556962025 2.19476008242567 0.231368032297811 0.487499540392301 GO:0019903 protein phosphatase binding 3/215 144/18639 0.0208333333333333 1.80610465116279 0.231647397307933 0.487499540392301 GO:0005283 amino acid:sodium symporter activity 1/215 23/18639 0.0434782608695652 3.76926188068756 0.234330346230063 0.487499540392301 GO:0016917 GABA receptor activity 1/215 23/18639 0.0434782608695652 3.76926188068756 0.234330346230063 0.487499540392301 GO:0043274 phospholipase binding 1/215 23/18639 0.0434782608695652 3.76926188068756 0.234330346230063 0.487499540392301 GO:0044013 histone H2B acetyltransferase activity 1/215 23/18639 0.0434782608695652 3.76926188068756 0.234330346230063 0.487499540392301 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/215 23/18639 0.0434782608695652 3.76926188068756 0.234330346230063 0.487499540392301 GO:0099186 structural constituent of postsynapse 1/215 23/18639 0.0434782608695652 3.76926188068756 0.234330346230063 0.487499540392301 GO:0015293 symporter activity 3/215 146/18639 0.0205479452054795 1.78136349155782 0.237756544887225 0.487499540392301 GO:0001618 virus receptor activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0030971 receptor tyrosine kinase binding 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0033192 calmodulin-dependent protein phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0140791 histone H2AXS140 phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/215 81/18639 0.0246913580246914 2.1405684754522 0.239893511049027 0.487499540392301 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0015149 hexose transmembrane transporter activity 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0030552 cAMP binding 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0035035 histone acetyltransferase binding 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0043998 histone H2A acetyltransferase activity 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0055056 D-glucose transmembrane transporter activity 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/215 24/18639 0.0416666666666667 3.61220930232558 0.243173222012215 0.487499540392301 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/215 82/18639 0.024390243902439 2.11446398184912 0.244162206355535 0.487499540392301 GO:0033549 MAP kinase phosphatase activity 2/215 82/18639 0.024390243902439 2.11446398184912 0.244162206355535 0.487499540392301 GO:0140272 exogenous protein binding 2/215 82/18639 0.024390243902439 2.11446398184912 0.244162206355535 0.487499540392301 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/215 83/18639 0.0240963855421687 2.08898851218829 0.248433999988108 0.491284799838382 GO:0003707 nuclear steroid receptor activity 1/215 25/18639 0.04 3.46772093023256 0.251914439163296 0.491284799838382 GO:0004709 MAP kinase kinase kinase activity 1/215 25/18639 0.04 3.46772093023256 0.251914439163296 0.491284799838382 GO:0015645 fatty acid ligase activity 1/215 25/18639 0.04 3.46772093023256 0.251914439163296 0.491284799838382 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/215 25/18639 0.04 3.46772093023256 0.251914439163296 0.491284799838382 GO:0120515 fatty acid-CoA ligase activity 1/215 25/18639 0.04 3.46772093023256 0.251914439163296 0.491284799838382 GO:0004860 protein kinase inhibitor activity 2/215 84/18639 0.0238095238095238 2.0641196013289 0.25270825575443 0.491284799838382 GO:0017018 myosin phosphatase activity 2/215 84/18639 0.0238095238095238 2.0641196013289 0.25270825575443 0.491284799838382 GO:0003774 cytoskeletal motor activity 3/215 153/18639 0.0196078431372549 1.69986320109439 0.259342480008499 0.491737746776999 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0008143 poly(A) binding 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0015145 monosaccharide transmembrane transporter activity 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0030507 spectrin binding 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0034237 protein kinase A regulatory subunit binding 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0052742 phosphatidylinositol kinase activity 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0070006 metalloaminopeptidase activity 1/215 26/18639 0.0384615384615385 3.33434704830054 0.26055516096301 0.491737746776999 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/215 86/18639 0.0232558139534884 2.01611681990265 0.26126167933668 0.491737746776999 GO:0005506 iron ion binding 3/215 154/18639 0.0194805194805195 1.68882512836001 0.262448471454683 0.492403322634024 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/215 27/18639 0.037037037037037 3.21085271317829 0.269096537441436 0.495439419401523 GO:0005044 scavenger receptor activity 1/215 27/18639 0.037037037037037 3.21085271317829 0.269096537441436 0.495439419401523 GO:0008266 poly(U) RNA binding 1/215 27/18639 0.037037037037037 3.21085271317829 0.269096537441436 0.495439419401523 GO:0016405 CoA-ligase activity 1/215 27/18639 0.037037037037037 3.21085271317829 0.269096537441436 0.495439419401523 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/215 27/18639 0.037037037037037 3.21085271317829 0.269096537441436 0.495439419401523 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/215 27/18639 0.037037037037037 3.21085271317829 0.269096537441436 0.495439419401523 GO:0031625 ubiquitin protein ligase binding 5/215 302/18639 0.0165562913907285 1.43531495456646 0.270061703738736 0.495535020835084 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/215 89/18639 0.0224719101123595 1.94815782597335 0.274095175780611 0.495535020835084 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/215 89/18639 0.0224719101123595 1.94815782597335 0.274095175780611 0.495535020835084 GO:0000287 magnesium ion binding 4/215 230/18639 0.0173913043478261 1.50770475227503 0.274642893262537 0.495535020835084 GO:0036408 histone H3K14 acetyltransferase activity 1/215 28/18639 0.0357142857142857 3.09617940199336 0.277539705529235 0.495535020835084 GO:0046966 nuclear thyroid hormone receptor binding 1/215 28/18639 0.0357142857142857 3.09617940199336 0.277539705529235 0.495535020835084 GO:0051019 mitogen-activated protein kinase binding 1/215 28/18639 0.0357142857142857 3.09617940199336 0.277539705529235 0.495535020835084 GO:0051119 sugar transmembrane transporter activity 1/215 28/18639 0.0357142857142857 3.09617940199336 0.277539705529235 0.495535020835084 GO:0051537 2 iron, 2 sulfur cluster binding 1/215 28/18639 0.0357142857142857 3.09617940199336 0.277539705529235 0.495535020835084 GO:0019210 kinase inhibitor activity 2/215 90/18639 0.0222222222222222 1.92651162790698 0.278371619149319 0.495535020835084 GO:0140793 histone H2AXY142 phosphatase activity 2/215 90/18639 0.0222222222222222 1.92651162790698 0.278371619149319 0.495535020835084 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/215 91/18639 0.021978021978022 1.90534117045745 0.282646453859678 0.498898680103118 GO:0005416 amino acid:monoatomic cation symporter activity 1/215 29/18639 0.0344827586206897 2.98941459502807 0.285885789206158 0.498898680103118 GO:0010484 histone H3 acetyltransferase activity 1/215 29/18639 0.0344827586206897 2.98941459502807 0.285885789206158 0.498898680103118 GO:0043236 laminin binding 1/215 29/18639 0.0344827586206897 2.98941459502807 0.285885789206158 0.498898680103118 GO:0051219 phosphoprotein binding 2/215 93/18639 0.021505376344086 1.86436609152288 0.291189191105542 0.498898680103118 GO:0015081 sodium ion transmembrane transporter activity 3/215 164/18639 0.0182926829268293 1.58584798638684 0.293729171548594 0.498898680103118 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0008187 poly-pyrimidine tract binding 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0031624 ubiquitin conjugating enzyme binding 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0033612 receptor serine/threonine kinase binding 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0043995 histone H4K5 acetyltransferase activity 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0043996 histone H4K8 acetyltransferase activity 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0043997 histone H4K12 acetyltransferase activity 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0051721 protein phosphatase 2A binding 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0070566 adenylyltransferase activity 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0098918 structural constituent of synapse 1/215 30/18639 0.0333333333333333 2.88976744186047 0.294135899647892 0.498898680103118 GO:0016410 N-acyltransferase activity 2/215 94/18639 0.0212765957446809 1.84453240969817 0.295456071127058 0.498898680103118 GO:0042562 hormone binding 2/215 94/18639 0.0212765957446809 1.84453240969817 0.295456071127058 0.498898680103118 GO:0004867 serine-type endopeptidase inhibitor activity 2/215 95/18639 0.0210526315789474 1.82511627906977 0.299719297042582 0.50465556852469 GO:0016878 acid-thiol ligase activity 1/215 31/18639 0.032258064516129 2.79654913728432 0.302291135371236 0.504672488712995 GO:0070273 phosphatidylinositol-4-phosphate binding 1/215 31/18639 0.032258064516129 2.79654913728432 0.302291135371236 0.504672488712995 GO:0072349 modified amino acid transmembrane transporter activity 1/215 31/18639 0.032258064516129 2.79654913728432 0.302291135371236 0.504672488712995 GO:0016407 acetyltransferase activity 2/215 96/18639 0.0208333333333333 1.80610465116279 0.303978387242349 0.506059793972475 GO:0030414 peptidase inhibitor activity 3/215 169/18639 0.0177514792899408 1.53892940690794 0.309470788296139 0.5080841445573 GO:0042910 xenobiotic transmembrane transporter activity 1/215 32/18639 0.03125 2.70915697674419 0.31035258237764 0.5080841445573 GO:0051059 NF-kappaB binding 1/215 32/18639 0.03125 2.70915697674419 0.31035258237764 0.5080841445573 GO:0070717 poly-purine tract binding 1/215 32/18639 0.03125 2.70915697674419 0.31035258237764 0.5080841445573 GO:0071813 lipoprotein particle binding 1/215 32/18639 0.03125 2.70915697674419 0.31035258237764 0.5080841445573 GO:0071814 protein-lipid complex binding 1/215 32/18639 0.03125 2.70915697674419 0.31035258237764 0.5080841445573 GO:0004725 protein tyrosine phosphatase activity 2/215 98/18639 0.0204081632653061 1.76924537256763 0.312482291317835 0.510157552952599 GO:0030296 protein tyrosine kinase activator activity 1/215 33/18639 0.0303030303030303 2.62706131078224 0.318321314295135 0.515418895201163 GO:0140311 protein sequestering activity 1/215 33/18639 0.0303030303030303 2.62706131078224 0.318321314295135 0.515418895201163 GO:0140416 transcription regulator inhibitor activity 1/215 33/18639 0.0303030303030303 2.62706131078224 0.318321314295135 0.515418895201163 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/215 34/18639 0.0294117647058824 2.54979480164159 0.32619839251864 0.523867527115534 GO:0016831 carboxy-lyase activity 1/215 34/18639 0.0294117647058824 2.54979480164159 0.32619839251864 0.523867527115534 GO:0019825 oxygen binding 1/215 34/18639 0.0294117647058824 2.54979480164159 0.32619839251864 0.523867527115534 GO:0004721 phosphoprotein phosphatase activity 3/215 175/18639 0.0171428571428571 1.48616611295681 0.328395946702349 0.525967491872869 GO:0010485 histone H4 acetyltransferase activity 1/215 35/18639 0.0285714285714286 2.47694352159468 0.333984866348712 0.533473124356997 GO:0003924 GTPase activity 5/215 331/18639 0.0151057401812689 1.30956228483103 0.335115901633585 0.533836921470212 GO:0005319 lipid transporter activity 3/215 178/18639 0.0168539325842697 1.46111836948001 0.337859143790427 0.53421674052663 GO:0019887 protein kinase regulator activity 4/215 255/18639 0.0156862745098039 1.35989056087551 0.339453170721467 0.53421674052663 GO:0000993 RNA polymerase II complex binding 1/215 36/18639 0.0277777777777778 2.40813953488372 0.341681773128707 0.53421674052663 GO:0004033 aldo-keto reductase (NADPH) activity 1/215 36/18639 0.0277777777777778 2.40813953488372 0.341681773128707 0.53421674052663 GO:0004190 aspartic-type endopeptidase activity 1/215 36/18639 0.0277777777777778 2.40813953488372 0.341681773128707 0.53421674052663 GO:0016409 palmitoyltransferase activity 1/215 36/18639 0.0277777777777778 2.40813953488372 0.341681773128707 0.53421674052663 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/215 36/18639 0.0277777777777778 2.40813953488372 0.341681773128707 0.53421674052663 GO:0003712 transcription coregulator activity 7/215 495/18639 0.0141414141414141 1.22596194503171 0.346259726981571 0.539945906717964 GO:0030280 structural constituent of skin epidermis 1/215 37/18639 0.027027027027027 2.34305468258957 0.349290138380405 0.540393905190626 GO:0030551 cyclic nucleotide binding 1/215 37/18639 0.027027027027027 2.34305468258957 0.349290138380405 0.540393905190626 GO:0070001 aspartic-type peptidase activity 1/215 37/18639 0.027027027027027 2.34305468258957 0.349290138380405 0.540393905190626 GO:0005496 steroid binding 2/215 108/18639 0.0185185185185185 1.60542635658915 0.354604682341406 0.543493007163443 GO:0000146 microfilament motor activity 1/215 38/18639 0.0263157894736842 2.28139534883721 0.356810975938098 0.543493007163443 GO:0005501 retinoid binding 1/215 38/18639 0.0263157894736842 2.28139534883721 0.356810975938098 0.543493007163443 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/215 38/18639 0.0263157894736842 2.28139534883721 0.356810975938098 0.543493007163443 GO:0019840 isoprenoid binding 1/215 38/18639 0.0263157894736842 2.28139534883721 0.356810975938098 0.543493007163443 GO:0042887 amide transmembrane transporter activity 1/215 38/18639 0.0263157894736842 2.28139534883721 0.356810975938098 0.543493007163443 GO:0003730 mRNA 3'-UTR binding 4/215 262/18639 0.0152671755725191 1.32355760695899 0.357771997241071 0.543555913546202 GO:1902936 phosphatidylinositol bisphosphate binding 2/215 111/18639 0.018018018018018 1.56203645505971 0.367074476623085 0.553179075083428 GO:0004177 aminopeptidase activity 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:0004532 RNA exonuclease activity 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:0015144 carbohydrate transmembrane transporter activity 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:0061791 GTPase motor activity 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:0071855 neuropeptide receptor binding 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:1990606 membrane scission GTPase motor activity 1/215 40/18639 0.025 2.16732558139535 0.371594065665179 0.553179075083428 GO:0019902 phosphatase binding 3/215 190/18639 0.0157894736842105 1.36883720930233 0.375588087233745 0.557719998882269 GO:0001727 lipid kinase activity 1/215 41/18639 0.024390243902439 2.11446398184912 0.378858288251447 0.558367202884302 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/215 41/18639 0.024390243902439 2.11446398184912 0.378858288251447 0.558367202884302 GO:0042169 SH2 domain binding 1/215 41/18639 0.024390243902439 2.11446398184912 0.378858288251447 0.558367202884302 GO:0001221 transcription coregulator binding 2/215 115/18639 0.0173913043478261 1.50770475227503 0.383553820592984 0.56056266393859 GO:0004402 histone acetyltransferase activity 1/215 42/18639 0.0238095238095238 2.0641196013289 0.386038924235205 0.56056266393859 GO:0008307 structural constituent of muscle 1/215 42/18639 0.0238095238095238 2.0641196013289 0.386038924235205 0.56056266393859 GO:0019894 kinesin binding 1/215 42/18639 0.0238095238095238 2.0641196013289 0.386038924235205 0.56056266393859 GO:0043175 RNA polymerase core enzyme binding 1/215 42/18639 0.0238095238095238 2.0641196013289 0.386038924235205 0.56056266393859 GO:0051879 Hsp90 protein binding 1/215 42/18639 0.0238095238095238 2.0641196013289 0.386038924235205 0.56056266393859 GO:1990782 protein tyrosine kinase binding 2/215 117/18639 0.0170940170940171 1.48193202146691 0.391725055525611 0.565313689062333 GO:0005126 cytokine receptor binding 4/215 275/18639 0.0145454545454545 1.26098942917548 0.391752602451701 0.565313689062333 GO:0008200 ion channel inhibitor activity 1/215 43/18639 0.0232558139534884 2.01611681990265 0.393136930972283 0.565313689062333 GO:0048156 tau protein binding 1/215 43/18639 0.0232558139534884 2.01611681990265 0.393136930972283 0.565313689062333 GO:0016758 hexosyltransferase activity 3/215 197/18639 0.0152284263959391 1.3201983236926 0.397414312256587 0.57007732656224 GO:0001223 transcription coactivator binding 1/215 44/18639 0.0227272727272727 1.97029598308668 0.400153254904363 0.572616401085904 GO:0030246 carbohydrate binding 4/215 280/18639 0.0142857142857143 1.23847176079734 0.404766250715466 0.577818488340194 GO:0140303 intramembrane lipid transporter activity 1/215 45/18639 0.0222222222222222 1.92651162790698 0.407088831682828 0.5797337337941 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/215 46/18639 0.0217391304347826 1.88463094034378 0.413944586291207 0.588079929081978 GO:0043495 protein-membrane adaptor activity 1/215 47/18639 0.0212765957446809 1.84453240969817 0.420721433166234 0.59105720641154 GO:0061733 protein-lysine-acetyltransferase activity 1/215 47/18639 0.0212765957446809 1.84453240969817 0.420721433166234 0.59105720641154 GO:0099095 ligand-gated monoatomic anion channel activity 1/215 47/18639 0.0212765957446809 1.84453240969817 0.420721433166234 0.59105720641154 GO:0140938 histone H3 methyltransferase activity 1/215 47/18639 0.0212765957446809 1.84453240969817 0.420721433166234 0.59105720641154 GO:0046982 protein heterodimerization activity 5/215 369/18639 0.013550135501355 1.1747022121384 0.421882859340338 0.59105720641154 GO:0019207 kinase regulator activity 4/215 287/18639 0.0139372822299652 1.20826513248521 0.422896746527452 0.59105720641154 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/215 48/18639 0.0208333333333333 1.80610465116279 0.42742027631755 0.59105720641154 GO:0038187 pattern recognition receptor activity 1/215 48/18639 0.0208333333333333 1.80610465116279 0.42742027631755 0.59105720641154 GO:0005004 GPI-linked ephrin receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0005008 hepatocyte growth factor receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0005009 insulin receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0005011 macrophage colony-stimulating factor receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0005020 stem cell factor receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0008288 boss receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0036332 placental growth factor receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0038062 protein tyrosine kinase collagen receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0060175 brain-derived neurotrophic factor receptor activity 1/215 49/18639 0.0204081632653061 1.76924537256763 0.434042009446038 0.59105720641154 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/215 128/18639 0.015625 1.35457848837209 0.435745462824626 0.591789140890806 GO:0005006 epidermal growth factor receptor activity 1/215 50/18639 0.02 1.73386046511628 0.440587516060837 0.591789140890806 GO:0005007 fibroblast growth factor receptor activity 1/215 50/18639 0.02 1.73386046511628 0.440587516060837 0.591789140890806 GO:0005017 platelet-derived growth factor receptor activity 1/215 50/18639 0.02 1.73386046511628 0.440587516060837 0.591789140890806 GO:0005019 platelet-derived growth factor beta-receptor activity 1/215 50/18639 0.02 1.73386046511628 0.440587516060837 0.591789140890806 GO:0015605 organophosphate ester transmembrane transporter activity 1/215 50/18639 0.02 1.73386046511628 0.440587516060837 0.591789140890806 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/215 130/18639 0.0153846153846154 1.33373881932021 0.443566927966807 0.594440032717422 GO:0005021 vascular endothelial growth factor receptor activity 1/215 51/18639 0.0196078431372549 1.69986320109439 0.447057669595019 0.595070006150127 GO:0005030 neurotrophin receptor activity 1/215 51/18639 0.0196078431372549 1.69986320109439 0.447057669595019 0.595070006150127 GO:0016830 carbon-carbon lyase activity 1/215 51/18639 0.0196078431372549 1.69986320109439 0.447057669595019 0.595070006150127 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/215 52/18639 0.0192307692307692 1.66717352415027 0.453453333519975 0.599839378856442 GO:0005003 ephrin receptor activity 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0005005 transmembrane-ephrin receptor activity 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0016860 intramolecular oxidoreductase activity 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0017046 peptide hormone binding 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0034212 protein N-acetyltransferase activity 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0038064 collagen receptor activity 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0051018 protein kinase A binding 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/215 53/18639 0.0188679245283019 1.63571741992102 0.459775361458491 0.599839378856442 GO:0017069 snRNA binding 1/215 54/18639 0.0185185185185185 1.60542635658915 0.466024597296564 0.602182245249058 GO:0050661 NADP binding 1/215 54/18639 0.0185185185185185 1.60542635658915 0.466024597296564 0.602182245249058 GO:0002020 protease binding 2/215 136/18639 0.0147058823529412 1.27489740082079 0.466665767045801 0.602182245249058 GO:0016779 nucleotidyltransferase activity 2/215 136/18639 0.0147058823529412 1.27489740082079 0.466665767045801 0.602182245249058 GO:0044325 transmembrane transporter binding 2/215 136/18639 0.0147058823529412 1.27489740082079 0.466665767045801 0.602182245249058 GO:0098632 cell-cell adhesion mediator activity 1/215 55/18639 0.0181818181818182 1.57623678646934 0.472201875293941 0.606676757171128 GO:0140313 molecular sequestering activity 1/215 55/18639 0.0181818181818182 1.57623678646934 0.472201875293941 0.606676757171128 GO:0030295 protein kinase activator activity 2/215 139/18639 0.0143884892086331 1.24738162958006 0.478001740511782 0.612796157575841 GO:0061134 peptidase regulator activity 3/215 226/18639 0.0132743362831858 1.15079234410373 0.485099227252839 0.620549011485775 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/215 229/18639 0.0131004366812227 1.13571646186656 0.493838343071782 0.62796314362764 GO:0001786 phosphatidylserine binding 1/215 59/18639 0.0169491525423729 1.46937327552227 0.496207763238761 0.62796314362764 GO:0004879 nuclear receptor activity 1/215 59/18639 0.0169491525423729 1.46937327552227 0.496207763238761 0.62796314362764 GO:0031593 polyubiquitin modification-dependent protein binding 1/215 59/18639 0.0169491525423729 1.46937327552227 0.496207763238761 0.62796314362764 GO:0070063 RNA polymerase binding 1/215 59/18639 0.0169491525423729 1.46937327552227 0.496207763238761 0.62796314362764 GO:0008194 UDP-glycosyltransferase activity 2/215 145/18639 0.0137931034482759 1.19576583801123 0.500228600085616 0.628610434376881 GO:0001098 basal transcription machinery binding 1/215 60/18639 0.0166666666666667 1.44488372093023 0.502037436592027 0.628610434376881 GO:0001099 basal RNA polymerase II transcription machinery binding 1/215 60/18639 0.0166666666666667 1.44488372093023 0.502037436592027 0.628610434376881 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/215 60/18639 0.0166666666666667 1.44488372093023 0.502037436592027 0.628610434376881 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/215 60/18639 0.0166666666666667 1.44488372093023 0.502037436592027 0.628610434376881 GO:0019905 syntaxin binding 1/215 61/18639 0.0163934426229508 1.42119710255433 0.507799961546691 0.633690815671121 GO:0005125 cytokine activity 3/215 234/18639 0.0128205128205128 1.11144901610018 0.508239334396127 0.633690815671121 GO:0019209 kinase activator activity 2/215 148/18639 0.0135135135135135 1.17152734129478 0.511113435564046 0.635932716670213 GO:0008509 monoatomic anion transmembrane transporter activity 2/215 149/18639 0.0134228187919463 1.16366474168878 0.51470720269944 0.639058732763381 GO:0005507 copper ion binding 1/215 63/18639 0.0158730158730159 1.37607973421927 0.519126636946772 0.640509065627437 GO:0022824 transmitter-gated monoatomic ion channel activity 1/215 63/18639 0.0158730158730159 1.37607973421927 0.519126636946772 0.640509065627437 GO:0022835 transmitter-gated channel activity 1/215 63/18639 0.0158730158730159 1.37607973421927 0.519126636946772 0.640509065627437 GO:0008235 metalloexopeptidase activity 1/215 66/18639 0.0151515151515152 1.31353065539112 0.535632000311412 0.659496900383426 GO:0016500 protein-hormone receptor activity 1/215 67/18639 0.0149253731343284 1.29392572023603 0.541007498073381 0.660610395374727 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/215 67/18639 0.0149253731343284 1.29392572023603 0.541007498073381 0.660610395374727 GO:0042054 histone methyltransferase activity 1/215 67/18639 0.0149253731343284 1.29392572023603 0.541007498073381 0.660610395374727 GO:0050840 extracellular matrix binding 1/215 67/18639 0.0149253731343284 1.29392572023603 0.541007498073381 0.660610395374727 GO:0003777 microtubule motor activity 1/215 68/18639 0.0147058823529412 1.27489740082079 0.546321055466996 0.661630622502038 GO:0005548 phospholipid transporter activity 1/215 68/18639 0.0147058823529412 1.27489740082079 0.546321055466996 0.661630622502038 GO:0030145 manganese ion binding 1/215 68/18639 0.0147058823529412 1.27489740082079 0.546321055466996 0.661630622502038 GO:1990841 promoter-specific chromatin binding 1/215 68/18639 0.0147058823529412 1.27489740082079 0.546321055466996 0.661630622502038 GO:0016279 protein-lysine N-methyltransferase activity 1/215 69/18639 0.0144927536231884 1.25642062689585 0.551573382917031 0.666625499599111 GO:0004866 endopeptidase inhibitor activity 2/215 161/18639 0.0124223602484472 1.07693196591073 0.556455877508033 0.667440614600561 GO:0005178 integrin binding 2/215 161/18639 0.0124223602484472 1.07693196591073 0.556455877508033 0.667440614600561 GO:0016278 lysine N-methyltransferase activity 1/215 70/18639 0.0142857142857143 1.23847176079734 0.556765182737862 0.667440614600561 GO:0097110 scaffold protein binding 1/215 70/18639 0.0142857142857143 1.23847176079734 0.556765182737862 0.667440614600561 GO:0005518 collagen binding 1/215 72/18639 0.0138888888888889 1.20406976744186 0.566969968749353 0.678298080021999 GO:0015103 inorganic anion transmembrane transporter activity 2/215 165/18639 0.0121212121212121 1.0508245243129 0.569797491306602 0.680166464841127 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/215 73/18639 0.0136986301369863 1.18757566103855 0.571984319841015 0.680166464841127 GO:0043539 protein serine/threonine kinase activator activity 1/215 73/18639 0.0136986301369863 1.18757566103855 0.571984319841015 0.680166464841127 GO:0016874 ligase activity 2/215 167/18639 0.0119760479041916 1.03823979947083 0.576359190811372 0.683310733689814 GO:0031491 nucleosome binding 1/215 74/18639 0.0135135135135135 1.17152734129478 0.576940873284631 0.683310733689814 GO:0005201 extracellular matrix structural constituent 2/215 168/18639 0.0119047619047619 1.03205980066445 0.579612683702981 0.685102192136924 GO:0061630 ubiquitin protein ligase activity 4/215 353/18639 0.0113314447592068 0.982357204031886 0.583587375469259 0.688423430942778 GO:0017022 myosin binding 1/215 76/18639 0.0131578947368421 1.1406976744186 0.586683232151307 0.689323638571416 GO:0051536 iron-sulfur cluster binding 1/215 76/18639 0.0131578947368421 1.1406976744186 0.586683232151307 0.689323638571416 GO:0051540 metal cluster binding 1/215 77/18639 0.012987012987013 1.12588341890667 0.591470341190119 0.693569388181271 GO:0046873 metal ion transmembrane transporter activity 5/215 450/18639 0.0111111111111111 0.963255813953488 0.595920033549115 0.697403445203023 GO:0004252 serine-type endopeptidase activity 2/215 176/18639 0.0113636363636364 0.98514799154334 0.604982444821737 0.705823085427925 GO:0048306 calcium-dependent protein binding 1/215 80/18639 0.0125 1.08366279069767 0.605503052981316 0.705823085427925 GO:0043021 ribonucleoprotein complex binding 2/215 177/18639 0.0112994350282486 0.979582183681514 0.608071326915019 0.707421563399166 GO:0005254 chloride channel activity 1/215 83/18639 0.0120481927710843 1.04449425609414 0.619055915875366 0.717376561337924 GO:0030165 PDZ domain binding 1/215 83/18639 0.0120481927710843 1.04449425609414 0.619055915875366 0.717376561337924 GO:0004527 exonuclease activity 1/215 84/18639 0.0119047619047619 1.03205980066445 0.623469743105739 0.721077530676109 GO:0061659 ubiquitin-like protein ligase activity 4/215 372/18639 0.010752688172043 0.93218304576144 0.624916296233937 0.721338927879408 GO:0061135 endopeptidase regulator activity 2/215 184/18639 0.0108695652173913 0.942315470171891 0.629182059051819 0.724847167445663 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/215 88/18639 0.0113636363636364 0.98514799154334 0.64062180368568 0.736590439646375 GO:0003727 single-stranded RNA binding 1/215 89/18639 0.0112359550561798 0.974078912986674 0.644786879002783 0.739939894156591 GO:0015291 secondary active transmembrane transporter activity 3/215 287/18639 0.0104529616724739 0.906198849363909 0.646231149250481 0.74016009536247 GO:0072341 modified amino acid binding 1/215 91/18639 0.010989010989011 0.952670585228725 0.652973431622558 0.746435779669114 GO:0008236 serine-type peptidase activity 2/215 194/18639 0.0103092783505155 0.893742507791896 0.65779773464422 0.750498959796784 GO:0017171 serine hydrolase activity 2/215 198/18639 0.0101010101010101 0.87568710359408 0.668741742193825 0.760102574181059 GO:0008276 protein methyltransferase activity 1/215 95/18639 0.0105263157894737 0.912558139534884 0.668787374913961 0.760102574181059 GO:0004896 cytokine receptor activity 1/215 96/18639 0.0104166666666667 0.903052325581395 0.67262746952103 0.762999682316562 GO:0016829 lyase activity 2/215 200/18639 0.01 0.86693023255814 0.674107374982577 0.763213522250389 GO:0030594 neurotransmitter receptor activity 1/215 97/18639 0.0103092783505155 0.893742507791896 0.676423246582615 0.764371202161235 GO:0008170 N-methyltransferase activity 1/215 98/18639 0.0102040816326531 0.884622686283816 0.680175215193593 0.767144183548499 GO:0043130 ubiquitin binding 1/215 100/18639 0.01 0.86693023255814 0.687549734404217 0.77398455815789 GO:0008238 exopeptidase activity 1/215 102/18639 0.00980392156862745 0.849931600547196 0.694754984678105 0.780608737537566 GO:0005253 monoatomic anion channel activity 1/215 103/18639 0.00970873786407767 0.841679837435087 0.698295346025367 0.783097816889928 GO:0000149 SNARE binding 1/215 106/18639 0.00943396226415094 0.817858709960509 0.708673060560411 0.793230641650005 GO:0004843 cysteine-type deubiquitinase activity 1/215 108/18639 0.00925925925925926 0.802713178294574 0.715393359328973 0.799239083862803 GO:0005200 structural constituent of cytoskeleton 1/215 112/18639 0.00892857142857143 0.774044850498339 0.728374528280521 0.81220631361092 GO:0035401 histone H3Y41 kinase activity 1/215 115/18639 0.00869565217391304 0.753852376137513 0.737722097247764 0.817999548730635 GO:0101005 deubiquitinase activity 1/215 115/18639 0.00869565217391304 0.753852376137513 0.737722097247764 0.817999548730635 GO:0140801 histone H2AXY142 kinase activity 1/215 115/18639 0.00869565217391304 0.753852376137513 0.737722097247764 0.817999548730635 GO:0032182 ubiquitin-like protein binding 1/215 120/18639 0.00833333333333333 0.722441860465116 0.75259514919355 0.83143623816676 GO:0003697 single-stranded DNA binding 1/215 121/18639 0.00826446280991736 0.716471266576975 0.755467444831726 0.83143623816676 GO:0004540 RNA nuclease activity 1/215 121/18639 0.00826446280991736 0.716471266576975 0.755467444831726 0.83143623816676 GO:0015108 chloride transmembrane transporter activity 1/215 121/18639 0.00826446280991736 0.716471266576975 0.755467444831726 0.83143623816676 GO:0004842 ubiquitin-protein transferase activity 4/215 449/18639 0.0089086859688196 0.772320919873621 0.764332225129956 0.839628894148334 GO:0019783 ubiquitin-like protein peptidase activity 1/215 127/18639 0.0078740157480315 0.68262223036074 0.772017373634447 0.844930125588812 GO:0042826 histone deacetylase binding 1/215 127/18639 0.0078740157480315 0.68262223036074 0.772017373634447 0.844930125588812 GO:0031490 chromatin DNA binding 1/215 128/18639 0.0078125 0.677289244186047 0.774665183955784 0.84626085714948 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/215 130/18639 0.00769230769230769 0.666869409660107 0.779869325270899 0.848466012515106 GO:0033218 amide binding 2/215 247/18639 0.00809716599190283 0.701967799642218 0.780946421258627 0.848466012515106 GO:0005262 calcium channel activity 1/215 131/18639 0.00763358778625954 0.661778803479496 0.782426356718668 0.848466012515106 GO:0031072 heat shock protein binding 1/215 131/18639 0.00763358778625954 0.661778803479496 0.782426356718668 0.848466012515106 GO:0019838 growth factor binding 1/215 136/18639 0.00735294117647059 0.637448700410397 0.794774773580354 0.860278188985328 GO:0140767 enzyme-substrate adaptor activity 1/215 139/18639 0.00719424460431655 0.623690814790029 0.801846335492276 0.866345857908474 GO:0019787 ubiquitin-like protein transferase activity 4/215 479/18639 0.00835073068893528 0.723950089818906 0.806445102880095 0.86972455438346 GO:0019955 cytokine binding 1/215 144/18639 0.00694444444444444 0.60203488372093 0.813097319959225 0.875301486513483 GO:0005525 GTP binding 3/215 378/18639 0.00793650793650794 0.688039867109634 0.814654993370214 0.875383820148721 GO:0015085 calcium ion transmembrane transporter activity 1/215 147/18639 0.00680272108843537 0.589748457522544 0.819540284856385 0.878864611679623 GO:0016755 aminoacyltransferase activity 4/215 496/18639 0.00806451612903226 0.69913728432108 0.827480541211378 0.878864611679623 GO:0000510 H3-H4 histone complex chaperone activity 1/215 151/18639 0.00662251655629139 0.574125981826582 0.82778827461346 0.878864611679623 GO:0140584 chromatin extrusion motor activity 1/215 151/18639 0.00662251655629139 0.574125981826582 0.82778827461346 0.878864611679623 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/215 151/18639 0.00662251655629139 0.574125981826582 0.82778827461346 0.878864611679623 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/215 151/18639 0.00662251655629139 0.574125981826582 0.82778827461346 0.878864611679623 GO:0015616 DNA translocase activity 1/215 152/18639 0.00657894736842105 0.570348837209302 0.829790953159441 0.878864611679623 GO:0140674 ATP-dependent histone chaperone activity 1/215 152/18639 0.00657894736842105 0.570348837209302 0.829790953159441 0.878864611679623 GO:0061775 cohesin loader activity 1/215 153/18639 0.0065359477124183 0.566621067031464 0.831770449295684 0.879385215623881 GO:0140375 immune receptor activity 1/215 156/18639 0.00641025641025641 0.555724508050089 0.837572499094945 0.883938119580558 GO:0140658 ATP-dependent chromatin remodeler activity 1/215 158/18639 0.00632911392405063 0.548690020606417 0.841329436300918 0.88535131262707 GO:0019001 guanyl nucleotide binding 3/215 400/18639 0.0075 0.650197674418605 0.843405734363859 0.88535131262707 GO:0032561 guanyl ribonucleotide binding 3/215 400/18639 0.0075 0.650197674418605 0.843405734363859 0.88535131262707 GO:0003689 DNA clamp loader activity 1/215 160/18639 0.00625 0.541831395348837 0.844999870656989 0.885451992124611 GO:0140713 histone chaperone activity 1/215 164/18639 0.00609756097560976 0.52861599546228 0.852089116067544 0.891300296629944 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/215 167/18639 0.00598802395209581 0.519119899735413 0.857193399660913 0.895055298939222 GO:0001664 G protein-coupled receptor binding 2/215 297/18639 0.00673400673400673 0.583791402396054 0.859781898500474 0.896174783093087 GO:0016887 ATP hydrolysis activity 3/215 417/18639 0.00719424460431655 0.623690814790029 0.862912476715335 0.897854355173878 GO:0140030 modification-dependent protein binding 1/215 173/18639 0.00578034682080925 0.501115741363086 0.866881903021623 0.900399305247415 GO:0016853 isomerase activity 1/215 180/18639 0.00555555555555556 0.481627906976744 0.877361136269296 0.909684967605533 GO:0015276 ligand-gated monoatomic ion channel activity 1/215 186/18639 0.00537634408602151 0.46609152288072 0.88568707938272 0.912804192196554 GO:0008234 cysteine-type peptidase activity 1/215 187/18639 0.0053475935828877 0.463599054843925 0.887018964600989 0.912804192196554 GO:0031406 carboxylic acid binding 1/215 187/18639 0.0053475935828877 0.463599054843925 0.887018964600989 0.912804192196554 GO:0022834 ligand-gated channel activity 1/215 188/18639 0.00531914893617021 0.461133102424542 0.888335403068949 0.912804192196554 GO:0140597 protein carrier chaperone 1/215 188/18639 0.00531914893617021 0.461133102424542 0.888335403068949 0.912804192196554 GO:0043177 organic acid binding 1/215 189/18639 0.00529100529100529 0.458693244739756 0.88963657310527 0.912804192196554 GO:0022804 active transmembrane transporter activity 3/215 457/18639 0.00656455142231947 0.569100809119129 0.90063420568785 0.922486682082356 GO:0003714 transcription corepressor activity 1/215 204/18639 0.00490196078431373 0.424965800273598 0.907437094616959 0.926244081033891 GO:0008168 methyltransferase activity 1/215 204/18639 0.00490196078431373 0.424965800273598 0.907437094616959 0.926244081033891 GO:0004518 nuclease activity 1/215 209/18639 0.00478468899521531 0.414799154334038 0.912710832609521 0.92945596252888 GO:0008094 ATP-dependent activity, acting on DNA 1/215 210/18639 0.00476190476190476 0.412823920265781 0.913729127291504 0.92945596252888 GO:0016741 transferase activity, transferring one-carbon groups 1/215 215/18639 0.00465116279069767 0.40322336398053 0.91864594210912 0.931735808669558 GO:0045182 translation regulator activity 2/215 356/18639 0.00561797752808989 0.487039456493337 0.919123479618194 0.931735808669558 GO:0042277 peptide binding 1/215 249/18639 0.00401606425702811 0.348164752031381 0.945437193404214 0.955133985131436 GO:0140104 molecular carrier activity 1/215 249/18639 0.00401606425702811 0.348164752031381 0.945437193404214 0.955133985131436 GO:1901681 sulfur compound binding 1/215 275/18639 0.00363636363636364 0.315247357293869 0.959819459728557 0.968009045562419 GO:0005216 monoatomic ion channel activity 2/215 448/18639 0.00446428571428571 0.387022425249169 0.967015051135721 0.973604591518247 GO:0022836 gated channel activity 1/215 318/18639 0.00314465408805031 0.272619569986836 0.975798888768434 0.980777454527456 GO:0140097 catalytic activity, acting on DNA 1/215 336/18639 0.00297619047619048 0.258014950166113 0.980433535599222 0.983219834150016 GO:0005261 monoatomic cation channel activity 1/215 341/18639 0.00293255131964809 0.25423173975312 0.981556179608307 0.983219834150016 GO:0140098 catalytic activity, acting on RNA 1/215 387/18639 0.00258397932816537 0.224012979989183 0.989298766489997 0.989298766489997