ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0023026 MHC class II protein complex binding 9/151 27/18639 0.333333333333333 41.1456953642384 4.89064634473466e-13 2.26436925761215e-10 GO:0023023 MHC protein complex binding 9/151 37/18639 0.243243243243243 30.0252371576875 1.21182670215441e-11 2.80537881548746e-09 GO:0032395 MHC class II receptor activity 6/151 10/18639 0.6 74.0622516556291 5.23112458742713e-11 8.07336894659587e-09 GO:0042605 peptide antigen binding 8/151 45/18639 0.177777777777778 21.9443708609272 2.57521567090329e-09 2.98081213907055e-07 GO:0140375 immune receptor activity 10/151 156/18639 0.0641025641025641 7.912633723892 5.76141469675921e-07 5.33507000919903e-05 GO:0042277 peptide binding 11/151 249/18639 0.0441767068273092 5.45304396393521 6.00986428049481e-06 0.000463761193644849 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 6/151 68/18639 0.0882352941176471 10.8915075964161 1.85165510366315e-05 0.00122473758999434 GO:0003823 antigen binding 8/151 174/18639 0.0459770114942529 5.67526832610185 8.77823510567848e-05 0.00508040356741142 GO:0004129 cytochrome-c oxidase activity 3/151 15/18639 0.2 24.687417218543 0.000220798301138692 0.0113588459363571 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/151 16/18639 0.1875 23.1444536423841 0.000270140135860168 0.0125074882903258 GO:0009055 electron transfer activity 6/151 116/18639 0.0517241379310345 6.38467686686458 0.000365080531271987 0.0147017257833226 GO:0022853 active monoatomic ion transmembrane transporter activity 6/151 118/18639 0.0508474576271186 6.27646200471433 0.000400101335837287 0.0147017257833226 GO:0015399 primary active transmembrane transporter activity 7/151 166/18639 0.0421686746987952 5.20517832921088 0.000412791436680764 0.0147017257833226 GO:0140297 DNA-binding transcription factor binding 12/151 488/18639 0.0245901639344262 3.03533818260775 0.000633439978416075 0.0209487650004745 GO:0031683 G-protein beta/gamma-subunit complex binding 3/151 22/18639 0.136363636363636 16.8323299217339 0.000716873109681871 0.0214190976550455 GO:0005543 phospholipid binding 12/151 497/18639 0.0241448692152917 2.98037230002532 0.000743122359266245 0.0214190976550455 GO:0015078 proton transmembrane transporter activity 7/151 185/18639 0.0378378378378378 4.67059244675139 0.000786446350185257 0.0214190976550455 GO:0003779 actin binding 11/151 443/18639 0.0248306997742664 3.06502922577848 0.000985137756641589 0.0253399322958364 GO:0003924 GTPase activity 9/151 331/18639 0.027190332326284 3.35629539224905 0.00153308684079884 0.0373589056468348 GO:0017124 SH3 domain binding 5/151 115/18639 0.0434782608695652 5.36682983011805 0.00245280250984791 0.0567823781029791 GO:0042608 T cell receptor binding 2/151 11/18639 0.181818181818182 22.4431065623119 0.0034180110823718 0.0753590062446736 GO:0005525 GTP binding 9/151 378/18639 0.0238095238095238 2.93897824030274 0.00373143208371509 0.0765617400633296 GO:0015368 calcium:monoatomic cation antiporter activity 2/151 12/18639 0.166666666666667 20.5728476821192 0.00407987665918016 0.0765617400633296 GO:0045295 gamma-catenin binding 2/151 12/18639 0.166666666666667 20.5728476821192 0.00407987665918016 0.0765617400633296 GO:0022804 active transmembrane transporter activity 10/151 457/18639 0.0218818380743982 2.70103033025635 0.00413400324316035 0.0765617400633296 GO:0044325 transmembrane transporter binding 5/151 136/18639 0.0367647058823529 4.53812816517335 0.00502631883493253 0.0858474095559138 GO:0048156 tau protein binding 3/151 43/18639 0.0697674418604651 8.61188972739874 0.00507419461133917 0.0858474095559138 GO:0019001 guanyl nucleotide binding 9/151 400/18639 0.0225 2.77733443708609 0.00537705157045681 0.0858474095559138 GO:0032561 guanyl ribonucleotide binding 9/151 400/18639 0.0225 2.77733443708609 0.00537705157045681 0.0858474095559138 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/151 45/18639 0.0666666666666667 8.22913907284768 0.00576617632864068 0.0889913213386879 GO:0030695 GTPase regulator activity 10/151 489/18639 0.0204498977505112 2.52427578921708 0.00658290373666659 0.0936444643717601 GO:0005096 GTPase activator activity 7/151 271/18639 0.025830258302583 3.18841181789301 0.00665585194312558 0.0936444643717601 GO:0060589 nucleoside-triphosphatase regulator activity 10/151 490/18639 0.0204081632653061 2.51912420597378 0.00667444346494186 0.0936444643717601 GO:0032266 phosphatidylinositol-3-phosphate binding 3/151 48/18639 0.0625 7.7148178807947 0.00690544691167222 0.0940359388265952 GO:0004896 cytokine receptor activity 4/151 96/18639 0.0416666666666667 5.1432119205298 0.00772864179893435 0.102238890083046 GO:0010314 phosphatidylinositol-5-phosphate binding 2/151 21/18639 0.0952380952380952 11.755912961211 0.0123771381671168 0.159183749204863 GO:0001221 transcription coregulator binding 4/151 115/18639 0.0347826086956522 4.29346386409444 0.0143033148378311 0.169806019741431 GO:0035401 histone H3Y41 kinase activity 4/151 115/18639 0.0347826086956522 4.29346386409444 0.0143033148378311 0.169806019741431 GO:0140801 histone H2AXY142 kinase activity 4/151 115/18639 0.0347826086956522 4.29346386409444 0.0143033148378311 0.169806019741431 GO:0043274 phospholipase binding 2/151 23/18639 0.0869565217391304 10.7336596602361 0.0147549396383362 0.170788426313741 GO:0120020 cholesterol transfer activity 2/151 25/18639 0.08 9.87496688741722 0.0173125147802683 0.195504740079615 GO:0030247 polysaccharide binding 2/151 26/18639 0.0769230769230769 9.4951604686704 0.018656729589865 0.19631967727517 GO:0050750 low-density lipoprotein particle receptor binding 2/151 26/18639 0.0769230769230769 9.4951604686704 0.018656729589865 0.19631967727517 GO:0070412 R-SMAD binding 2/151 26/18639 0.0769230769230769 9.4951604686704 0.018656729589865 0.19631967727517 GO:0031490 chromatin DNA binding 4/151 128/18639 0.03125 3.85740894039735 0.0203759449857185 0.201895857053752 GO:0051019 mitogen-activated protein kinase binding 2/151 28/18639 0.0714285714285714 8.81693472090823 0.0214721233139238 0.201895857053752 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/151 28/18639 0.0714285714285714 8.81693472090823 0.0214721233139238 0.201895857053752 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 7/151 349/18639 0.0200573065902579 2.47581548036965 0.0237692434368457 0.201895857053752 GO:0001965 G-protein alpha-subunit binding 2/151 30/18639 0.0666666666666667 8.22913907284768 0.0244517270342426 0.201895857053752 GO:0004674 protein serine/threonine kinase activity 8/151 433/18639 0.0184757505773672 2.28059281464601 0.024934759555516 0.201895857053752 GO:0016922 nuclear receptor binding 4/151 137/18639 0.0291970802919708 3.60400251365592 0.0253841988655506 0.201895857053752 GO:0141003 histone H2AX kinase activity 7/151 354/18639 0.019774011299435 2.44084633516669 0.025430832617946 0.201895857053752 GO:0070273 phosphatidylinositol-4-phosphate binding 2/151 31/18639 0.0645161290322581 7.96368297372356 0.026001239624359 0.201895857053752 GO:0070325 lipoprotein particle receptor binding 2/151 31/18639 0.0645161290322581 7.96368297372356 0.026001239624359 0.201895857053752 GO:0140996 histone H3 kinase activity 7/151 357/18639 0.0196078431372549 2.42033502142579 0.0264651838097872 0.201895857053752 GO:0070851 growth factor receptor binding 4/151 139/18639 0.0287769784172662 3.55214636238029 0.0265890715717095 0.201895857053752 GO:0005516 calmodulin binding 5/151 207/18639 0.0241545893719807 2.98157212784336 0.0268050590185903 0.201895857053752 GO:0004713 protein tyrosine kinase activity 4/151 140/18639 0.0285714285714286 3.52677388836329 0.0272041807074492 0.201895857053752 GO:0035173 histone kinase activity 7/151 360/18639 0.0194444444444444 2.40016556291391 0.0275279757506236 0.201895857053752 GO:0071813 lipoprotein particle binding 2/151 32/18639 0.0625 7.7148178807947 0.0275895816276724 0.201895857053752 GO:0071814 protein-lipid complex binding 2/151 32/18639 0.0625 7.7148178807947 0.0275895816276724 0.201895857053752 GO:0120015 sterol transfer activity 2/151 32/18639 0.0625 7.7148178807947 0.0275895816276724 0.201895857053752 GO:0001618 virus receptor activity 3/151 81/18639 0.037037037037037 4.57174392935982 0.0280961082875986 0.201895857053752 GO:0035091 phosphatidylinositol binding 6/151 284/18639 0.0211267605633803 2.60782576252215 0.0283297575304958 0.201895857053752 GO:0042578 phosphoric ester hydrolase activity 7/151 363/18639 0.0192837465564738 2.38032948388156 0.0286195196626794 0.201895857053752 GO:0140272 exogenous protein binding 3/151 82/18639 0.0365853658536585 4.51599095461153 0.0289945013549077 0.201895857053752 GO:0071889 14-3-3 protein binding 2/151 33/18639 0.0606060606060606 7.48103552077062 0.029216031150327 0.201895857053752 GO:0001540 amyloid-beta binding 3/151 83/18639 0.036144578313253 4.4615814250379 0.0299080100538082 0.203638362572253 GO:0051427 hormone receptor binding 2/151 34/18639 0.0588235294117647 7.26100506427737 0.0308798753096506 0.204248318119546 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/151 34/18639 0.0588235294117647 7.26100506427737 0.0308798753096506 0.204248318119546 GO:0005154 epidermal growth factor receptor binding 2/151 35/18639 0.0571428571428571 7.05354777672658 0.0325804101371281 0.212460984415357 GO:0003774 cytoskeletal motor activity 4/151 153/18639 0.0261437908496732 3.22711336190105 0.0359774706166796 0.231355123548926 GO:0015631 tubulin binding 7/151 385/18639 0.0181818181818182 2.24431065623119 0.0375300891067682 0.237101365522449 GO:0000146 microfilament motor activity 2/151 38/18639 0.0526315789473684 6.49668874172185 0.0378952506450567 0.237101365522449 GO:0005085 guanyl-nucleotide exchange factor activity 5/151 230/18639 0.0217391304347826 2.68341491505903 0.0394591477416266 0.243594472058308 GO:0071855 neuropeptide receptor binding 2/151 40/18639 0.05 6.17185430463576 0.0416094173658393 0.251847692916407 GO:0051020 GTPase binding 6/151 315/18639 0.019047619047619 2.35118259224219 0.0434258680177655 0.251847692916407 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/151 41/18639 0.0487804878048781 6.02132127281538 0.0435158000719493 0.251847692916407 GO:0042169 SH2 domain binding 2/151 41/18639 0.0487804878048781 6.02132127281538 0.0435158000719493 0.251847692916407 GO:0140828 metal cation:monoatomic cation antiporter activity 2/151 41/18639 0.0487804878048781 6.02132127281538 0.0435158000719493 0.251847692916407 GO:0004725 protein tyrosine phosphatase activity 3/151 98/18639 0.0306122448979592 3.77868630896067 0.0454008124583852 0.25951328602756 GO:0003712 transcription coregulator activity 8/151 495/18639 0.0161616161616162 1.99494280553883 0.0486206855146954 0.266087388568875 GO:0001046 core promoter sequence-specific DNA binding 2/151 44/18639 0.0454545454545455 5.61077664057797 0.0494244393454065 0.266087388568875 GO:0001223 transcription coactivator binding 2/151 44/18639 0.0454545454545455 5.61077664057797 0.0494244393454065 0.266087388568875 GO:0003954 NADH dehydrogenase activity 2/151 44/18639 0.0454545454545455 5.61077664057797 0.0494244393454065 0.266087388568875 GO:0043014 alpha-tubulin binding 2/151 44/18639 0.0454545454545455 5.61077664057797 0.0494244393454065 0.266087388568875 GO:0033218 amide binding 5/151 247/18639 0.0202429149797571 2.49872643912379 0.0508118054284019 0.270412251877587 GO:0030276 clathrin binding 2/151 46/18639 0.0434782608695652 5.36682983011805 0.0535151816608352 0.281562830783713 GO:0000149 SNARE binding 3/151 106/18639 0.0283018867924528 3.49350243658628 0.0549996807885716 0.286121934888861 GO:0003713 transcription coactivator activity 5/151 256/18639 0.01953125 2.41088058774834 0.0575232659672102 0.295925246031315 GO:0035254 glutamate receptor binding 2/151 49/18639 0.0408163265306122 5.03824841194756 0.0598666055875682 0.304596026231253 GO:1901981 phosphatidylinositol phosphate binding 4/151 185/18639 0.0216216216216216 2.66890996957222 0.0637784784334015 0.320972125159401 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/151 268/18639 0.0186567164179104 2.30293071068499 0.0672282059535992 0.322266410263775 GO:0004864 protein phosphatase inhibitor activity 2/151 53/18639 0.0377358490566038 4.65800324878171 0.0687125084512094 0.322266410263775 GO:0003925 G protein activity 2/151 54/18639 0.037037037037037 4.57174392935982 0.0709875895801569 0.322266410263775 GO:0016791 phosphatase activity 5/151 273/18639 0.0183150183150183 2.26075249254057 0.0715257783320988 0.322266410263775 GO:0106310 protein serine kinase activity 6/151 361/18639 0.0166204986149584 2.05158591843848 0.073753061827332 0.322266410263775 GO:0008017 microtubule binding 5/151 276/18639 0.0181159420289855 2.23617909588252 0.0741755072191744 0.322266410263775 GO:0019212 phosphatase inhibitor activity 2/151 56/18639 0.0357142857142857 4.40846736045412 0.0756102405523388 0.322266410263775 GO:0001217 DNA-binding transcription repressor activity 5/151 278/18639 0.0179856115107914 2.22009147648768 0.0759715190161021 0.322266410263775 GO:0030246 carbohydrate binding 5/151 280/18639 0.0178571428571429 2.20423368022706 0.0777910663124108 0.322266410263775 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0005131 growth hormone receptor binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0005522 profilin binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0005528 FK506 binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0035256 G protein-coupled glutamate receptor binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0043422 protein kinase B binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0070097 delta-catenin binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:1990763 arrestin family protein binding 1/151 10/18639 0.1 12.3437086092715 0.0781406290507721 0.322266410263775 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/151 58/18639 0.0344827586206897 4.25645124457639 0.0803259944092689 0.322266410263775 GO:0031267 small GTPase binding 5/151 283/18639 0.0176678445229682 2.18086724545433 0.0805643416361676 0.322266410263775 GO:0004879 nuclear receptor activity 2/151 59/18639 0.0338983050847458 4.18430800314289 0.0827174801365135 0.322266410263775 GO:0003714 transcription corepressor activity 4/151 204/18639 0.0196078431372549 2.42033502142579 0.0843728337061721 0.322266410263775 GO:0098531 ligand-modulated transcription factor activity 2/151 60/18639 0.0333333333333333 4.11456953642384 0.0851306894948262 0.322266410263775 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/151 11/18639 0.0909090909090909 11.2215532811559 0.0856128908476118 0.322266410263775 GO:0008432 JUN kinase binding 1/151 11/18639 0.0909090909090909 11.2215532811559 0.0856128908476118 0.322266410263775 GO:0010854 adenylate cyclase regulator activity 1/151 11/18639 0.0909090909090909 11.2215532811559 0.0856128908476118 0.322266410263775 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/151 11/18639 0.0909090909090909 11.2215532811559 0.0856128908476118 0.322266410263775 GO:0045294 alpha-catenin binding 1/151 11/18639 0.0909090909090909 11.2215532811559 0.0856128908476118 0.322266410263775 GO:0050998 nitric-oxide synthase binding 1/151 11/18639 0.0909090909090909 11.2215532811559 0.0856128908476118 0.322266410263775 GO:0019905 syntaxin binding 2/151 61/18639 0.0327868852459016 4.04711757681034 0.0875651192076349 0.32695685639625 GO:0051015 actin filament binding 4/151 209/18639 0.0191387559808612 2.36243226971704 0.0902746407663831 0.327970253695145 GO:0005527 macrolide binding 1/151 12/18639 0.0833333333333333 10.2864238410596 0.0930249830465603 0.327970253695145 GO:0015132 prostaglandin transmembrane transporter activity 1/151 12/18639 0.0833333333333333 10.2864238410596 0.0930249830465603 0.327970253695145 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/151 12/18639 0.0833333333333333 10.2864238410596 0.0930249830465603 0.327970253695145 GO:0070008 serine-type exopeptidase activity 1/151 12/18639 0.0833333333333333 10.2864238410596 0.0930249830465603 0.327970253695145 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/151 12/18639 0.0833333333333333 10.2864238410596 0.0930249830465603 0.327970253695145 GO:0001664 G protein-coupled receptor binding 5/151 297/18639 0.0168350168350168 2.07806542243628 0.0941948733386542 0.327970253695145 GO:0120013 lipid transfer activity 2/151 65/18639 0.0307692307692308 3.79806418746816 0.0975052066150899 0.327970253695145 GO:0002020 protease binding 3/151 136/18639 0.0220588235294118 2.72287689910401 0.098532004044956 0.327970253695145 GO:0005172 vascular endothelial growth factor receptor binding 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0008035 high-density lipoprotein particle binding 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0031432 titin binding 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0039706 co-receptor binding 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0043560 insulin receptor substrate binding 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0071714 icosanoid transmembrane transporter activity 1/151 13/18639 0.0769230769230769 9.4951604686704 0.100377386952716 0.327970253695145 GO:0016500 protein-hormone receptor activity 2/151 67/18639 0.0298507462686567 3.68468913709598 0.10258996774789 0.327970253695145 GO:0004065 arylsulfatase activity 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0005161 platelet-derived growth factor receptor binding 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0005545 1-phosphatidylinositol binding 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0008474 palmitoyl-(protein) hydrolase activity 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0032036 myosin heavy chain binding 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0046030 inositol trisphosphate phosphatase activity 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0071933 Arp2/3 complex binding 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0098599 palmitoyl hydrolase activity 1/151 14/18639 0.0714285714285714 8.81693472090823 0.107670580046786 0.327970253695145 GO:0019903 protein phosphatase binding 3/151 144/18639 0.0208333333333333 2.5716059602649 0.111934261284207 0.336529629705115 GO:0019955 cytokine binding 3/151 144/18639 0.0208333333333333 2.5716059602649 0.111934261284207 0.336529629705115 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/151 15/18639 0.0666666666666667 8.22913907284768 0.114905036015266 0.33886007436349 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/151 15/18639 0.0666666666666667 8.22913907284768 0.114905036015266 0.33886007436349 GO:0050700 CARD domain binding 1/151 15/18639 0.0666666666666667 8.22913907284768 0.114905036015266 0.33886007436349 GO:0043539 protein serine/threonine kinase activator activity 2/151 73/18639 0.0273972602739726 3.38183797514288 0.118259105459509 0.346544087517422 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/151 16/18639 0.0625 7.7148178807947 0.122081224780391 0.348161808748073 GO:0004708 MAP kinase kinase activity 1/151 16/18639 0.0625 7.7148178807947 0.122081224780391 0.348161808748073 GO:0005159 insulin-like growth factor receptor binding 1/151 16/18639 0.0625 7.7148178807947 0.122081224780391 0.348161808748073 GO:0140328 floppase activity 1/151 16/18639 0.0625 7.7148178807947 0.122081224780391 0.348161808748073 GO:0004857 enzyme inhibitor activity 6/151 416/18639 0.0144230769230769 1.7803425878757 0.122571003943706 0.348161808748073 GO:0019003 GDP binding 2/151 75/18639 0.0266666666666667 3.29165562913907 0.123608774595189 0.348968674619345 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0005092 GDP-dissociation inhibitor activity 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0008484 sulfuric ester hydrolase activity 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0032183 SUMO binding 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0046965 nuclear retinoid X receptor binding 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0051787 misfolded protein binding 1/151 17/18639 0.0588235294117647 7.26100506427737 0.129199612529849 0.349821173107136 GO:0046332 SMAD binding 2/151 79/18639 0.0253164556962025 3.12498952133456 0.134478033660681 0.354430822407405 GO:0004706 JUN kinase kinase kinase activity 1/151 18/18639 0.0555555555555556 6.85761589403973 0.13626066174626 0.354430822407405 GO:0008525 phosphatidylcholine transporter activity 1/151 18/18639 0.0555555555555556 6.85761589403973 0.13626066174626 0.354430822407405 GO:0017075 syntaxin-1 binding 1/151 18/18639 0.0555555555555556 6.85761589403973 0.13626066174626 0.354430822407405 GO:0034185 apolipoprotein binding 1/151 18/18639 0.0555555555555556 6.85761589403973 0.13626066174626 0.354430822407405 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/151 18/18639 0.0555555555555556 6.85761589403973 0.13626066174626 0.354430822407405 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/151 18/18639 0.0555555555555556 6.85761589403973 0.13626066174626 0.354430822407405 GO:0048306 calcium-dependent protein binding 2/151 80/18639 0.025 3.08592715231788 0.137228422887542 0.354953965345987 GO:0005178 integrin binding 3/151 161/18639 0.0186335403726708 2.30006992719345 0.142516356710134 0.35662159603475 GO:0008574 plus-end-directed microtubule motor activity 1/151 19/18639 0.0526315789473684 6.49668874172185 0.143264831236422 0.35662159603475 GO:0022821 solute:potassium antiporter activity 1/151 19/18639 0.0526315789473684 6.49668874172185 0.143264831236422 0.35662159603475 GO:0030506 ankyrin binding 1/151 19/18639 0.0526315789473684 6.49668874172185 0.143264831236422 0.35662159603475 GO:0043395 heparan sulfate proteoglycan binding 1/151 19/18639 0.0526315789473684 6.49668874172185 0.143264831236422 0.35662159603475 GO:0046624 sphingolipid transporter activity 1/151 19/18639 0.0526315789473684 6.49668874172185 0.143264831236422 0.35662159603475 GO:0050145 nucleoside monophosphate kinase activity 1/151 19/18639 0.0526315789473684 6.49668874172185 0.143264831236422 0.35662159603475 GO:0051117 ATPase binding 2/151 84/18639 0.0238095238095238 2.93897824030274 0.148350763091752 0.362231368553314 GO:0001614 purinergic nucleotide receptor activity 1/151 20/18639 0.05 6.17185430463576 0.150212576160338 0.362231368553314 GO:0010851 cyclase regulator activity 1/151 20/18639 0.05 6.17185430463576 0.150212576160338 0.362231368553314 GO:0016004 phospholipase activator activity 1/151 20/18639 0.05 6.17185430463576 0.150212576160338 0.362231368553314 GO:0016502 nucleotide receptor activity 1/151 20/18639 0.05 6.17185430463576 0.150212576160338 0.362231368553314 GO:0052745 inositol phosphate phosphatase activity 1/151 20/18639 0.05 6.17185430463576 0.150212576160338 0.362231368553314 GO:0016209 antioxidant activity 2/151 86/18639 0.0232558139534884 2.87062990913291 0.15397923191571 0.36737026844333 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/151 21/18639 0.0476190476190476 5.87795648060549 0.157104348059999 0.36737026844333 GO:0001846 opsonin binding 1/151 21/18639 0.0476190476190476 5.87795648060549 0.157104348059999 0.36737026844333 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/151 21/18639 0.0476190476190476 5.87795648060549 0.157104348059999 0.36737026844333 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/151 21/18639 0.0476190476190476 5.87795648060549 0.157104348059999 0.36737026844333 GO:0051428 peptide hormone receptor binding 1/151 21/18639 0.0476190476190476 5.87795648060549 0.157104348059999 0.36737026844333 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/151 88/18639 0.0227272727272727 2.80538832028898 0.159648748925739 0.371444074133755 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/151 89/18639 0.0224719101123595 2.77386710320708 0.162498033779919 0.374311391244292 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/151 89/18639 0.0224719101123595 2.77386710320708 0.162498033779919 0.374311391244292 GO:0050321 tau-protein kinase activity 1/151 22/18639 0.0454545454545455 5.61077664057797 0.163940594887957 0.375446809423372 GO:0140793 histone H2AXY142 phosphatase activity 2/151 90/18639 0.0222222222222222 2.74304635761589 0.165356550358918 0.375446809423372 GO:0004721 phosphoprotein phosphatase activity 3/151 175/18639 0.0171428571428571 2.11606433301798 0.169539800272201 0.375446809423372 GO:0004602 glutathione peroxidase activity 1/151 23/18639 0.0434782608695652 5.36682983011805 0.170721761035668 0.375446809423372 GO:0005158 insulin receptor binding 1/151 23/18639 0.0434782608695652 5.36682983011805 0.170721761035668 0.375446809423372 GO:0016493 C-C chemokine receptor activity 1/151 23/18639 0.0434782608695652 5.36682983011805 0.170721761035668 0.375446809423372 GO:0042171 lysophosphatidic acid acyltransferase activity 1/151 23/18639 0.0434782608695652 5.36682983011805 0.170721761035668 0.375446809423372 GO:0071617 lysophospholipid acyltransferase activity 1/151 23/18639 0.0434782608695652 5.36682983011805 0.170721761035668 0.375446809423372 GO:0140103 catalytic activity, acting on a glycoprotein 1/151 23/18639 0.0434782608695652 5.36682983011805 0.170721761035668 0.375446809423372 GO:0043178 alcohol binding 2/151 92/18639 0.0217391304347826 2.68341491505903 0.171099949866807 0.375446809423372 GO:0005319 lipid transporter activity 3/151 178/18639 0.0168539325842697 2.08040032740531 0.175514875693846 0.382132823481034 GO:0042562 hormone binding 2/151 94/18639 0.0212765957446809 2.62632098069607 0.176876336764517 0.382132823481034 GO:0019957 C-C chemokine binding 1/151 24/18639 0.0416666666666667 5.1432119205298 0.177448287361603 0.382132823481034 GO:0060229 lipase activator activity 1/151 24/18639 0.0416666666666667 5.1432119205298 0.177448287361603 0.382132823481034 GO:0001848 complement binding 1/151 25/18639 0.04 4.93748344370861 0.184120611219158 0.389040678776409 GO:0004709 MAP kinase kinase kinase activity 1/151 25/18639 0.04 4.93748344370861 0.184120611219158 0.389040678776409 GO:0042974 nuclear retinoic acid receptor binding 1/151 25/18639 0.04 4.93748344370861 0.184120611219158 0.389040678776409 GO:0047617 fatty acyl-CoA hydrolase activity 1/151 25/18639 0.04 4.93748344370861 0.184120611219158 0.389040678776409 GO:0001637 G protein-coupled chemoattractant receptor activity 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0004435 phosphatidylinositol phospholipase C activity 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0004950 chemokine receptor activity 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0016289 acyl-CoA hydrolase activity 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0043548 phosphatidylinositol 3-kinase binding 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0050681 nuclear androgen receptor binding 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0052742 phosphatidylinositol kinase activity 1/151 26/18639 0.0384615384615385 4.7475802343352 0.19073916648433 0.389040678776409 GO:0004364 glutathione transferase activity 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0008320 protein transmembrane transporter activity 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0015252 proton channel activity 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0035255 ionotropic glutamate receptor binding 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/151 27/18639 0.037037037037037 4.57174392935982 0.197304383583179 0.390392861534239 GO:0019902 phosphatase binding 3/151 190/18639 0.0157894736842105 1.94900662251656 0.199971923455844 0.39398723642577 GO:0046875 ephrin receptor binding 1/151 28/18639 0.0357142857142857 4.40846736045412 0.203816689519077 0.396500534652658 GO:0051959 dynein light intermediate chain binding 1/151 28/18639 0.0357142857142857 4.40846736045412 0.203816689519077 0.396500534652658 GO:0097718 disordered domain specific binding 1/151 28/18639 0.0357142857142857 4.40846736045412 0.203816689519077 0.396500534652658 GO:0003785 actin monomer binding 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0004629 phospholipase C activity 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0035250 UDP-galactosyltransferase activity 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0051861 glycolipid binding 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0097472 cyclin-dependent protein kinase activity 1/151 29/18639 0.0344827586206897 4.25645124457639 0.210276507899746 0.397379686357478 GO:0008013 beta-catenin binding 2/151 106/18639 0.0188679245283019 2.32900162439085 0.212090303649767 0.399178091828626 GO:0019888 protein phosphatase regulator activity 2/151 107/18639 0.0186915887850467 2.30723525406944 0.215058449542093 0.401299247601464 GO:0031210 phosphatidylcholine binding 1/151 30/18639 0.0333333333333333 4.11456953642384 0.216684258964073 0.401299247601464 GO:0048019 receptor antagonist activity 1/151 30/18639 0.0333333333333333 4.11456953642384 0.216684258964073 0.401299247601464 GO:0051721 protein phosphatase 2A binding 1/151 30/18639 0.0333333333333333 4.11456953642384 0.216684258964073 0.401299247601464 GO:0016411 acylglycerol O-acyltransferase activity 1/151 31/18639 0.032258064516129 3.98184148686178 0.223040359608731 0.411425045812121 GO:1902936 phosphatidylinositol bisphosphate binding 2/151 111/18639 0.018018018018018 2.22409164131018 0.226967610599602 0.417007951220698 GO:0008378 galactosyltransferase activity 1/151 32/18639 0.03125 3.85740894039735 0.229345223414571 0.418058419058844 GO:0022884 macromolecule transmembrane transporter activity 1/151 32/18639 0.03125 3.85740894039735 0.229345223414571 0.418058419058844 GO:0019956 chemokine binding 1/151 33/18639 0.0303030303030303 3.74051776038531 0.235599260672829 0.426103350357499 GO:0140416 transcription regulator inhibitor activity 1/151 33/18639 0.0303030303030303 3.74051776038531 0.235599260672829 0.426103350357499 GO:0019208 phosphatase regulator activity 2/151 117/18639 0.0170940170940171 2.11003565970453 0.244914057195238 0.439516311943393 GO:1990782 protein tyrosine kinase binding 2/151 117/18639 0.0170940170940171 2.11003565970453 0.244914057195238 0.439516311943393 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/151 36/18639 0.0277777777777778 3.42880794701987 0.254060467274503 0.45068964118044 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/151 36/18639 0.0277777777777778 3.42880794701987 0.254060467274503 0.45068964118044 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/151 36/18639 0.0277777777777778 3.42880794701987 0.254060467274503 0.45068964118044 GO:0043394 proteoglycan binding 1/151 37/18639 0.027027027027027 3.33613746196528 0.260115236367743 0.456171288661165 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/151 39/18639 0.0256410256410256 3.1650534895568 0.272078695046944 0.456171288661165 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/151 39/18639 0.0256410256410256 3.1650534895568 0.272078695046944 0.456171288661165 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/151 128/18639 0.015625 1.92870447019868 0.277925745660316 0.456171288661165 GO:0030331 nuclear estrogen receptor binding 1/151 40/18639 0.025 3.08592715231788 0.277988163705433 0.456171288661165 GO:0050997 quaternary ammonium group binding 1/151 40/18639 0.025 3.08592715231788 0.277988163705433 0.456171288661165 GO:0061791 GTPase motor activity 1/151 40/18639 0.025 3.08592715231788 0.277988163705433 0.456171288661165 GO:1990606 membrane scission GTPase motor activity 1/151 40/18639 0.025 3.08592715231788 0.277988163705433 0.456171288661165 GO:0035591 signaling adaptor activity 2/151 129/18639 0.0155038759689922 1.91375327275527 0.280926397038464 0.456171288661165 GO:0001727 lipid kinase activity 1/151 41/18639 0.024390243902439 3.01066063640769 0.283849972796271 0.456171288661165 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/151 41/18639 0.024390243902439 3.01066063640769 0.283849972796271 0.456171288661165 GO:0017080 sodium channel regulator activity 1/151 41/18639 0.024390243902439 3.01066063640769 0.283849972796271 0.456171288661165 GO:0042287 MHC protein binding 1/151 41/18639 0.024390243902439 3.01066063640769 0.283849972796271 0.456171288661165 GO:0140318 protein transporter activity 1/151 41/18639 0.024390243902439 3.01066063640769 0.283849972796271 0.456171288661165 GO:0045296 cadherin binding 4/151 334/18639 0.0119760479041916 1.47828845620018 0.286313832542711 0.456171288661165 GO:0004520 DNA endonuclease activity 1/151 42/18639 0.0238095238095238 2.93897824030274 0.289664504149522 0.456171288661165 GO:0016859 cis-trans isomerase activity 1/151 42/18639 0.0238095238095238 2.93897824030274 0.289664504149522 0.456171288661165 GO:0019894 kinesin binding 1/151 42/18639 0.0238095238095238 2.93897824030274 0.289664504149522 0.456171288661165 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/151 43/18639 0.0232558139534884 2.87062990913291 0.295432136556546 0.456171288661165 GO:0008200 ion channel inhibitor activity 1/151 43/18639 0.0232558139534884 2.87062990913291 0.295432136556546 0.456171288661165 GO:0008375 acetylglucosaminyltransferase activity 1/151 43/18639 0.0232558139534884 2.87062990913291 0.295432136556546 0.456171288661165 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/151 43/18639 0.0232558139534884 2.87062990913291 0.295432136556546 0.456171288661165 GO:0051087 protein-folding chaperone binding 2/151 134/18639 0.0149253731343284 1.84234456854799 0.29591256597228 0.456171288661165 GO:0015297 antiporter activity 2/151 135/18639 0.0148148148148148 1.82869757174393 0.29890515434616 0.456171288661165 GO:0016248 channel inhibitor activity 1/151 44/18639 0.0227272727272727 2.80538832028898 0.301153245794014 0.456171288661165 GO:0016790 thiolester hydrolase activity 1/151 44/18639 0.0227272727272727 2.80538832028898 0.301153245794014 0.456171288661165 GO:0019205 nucleobase-containing compound kinase activity 1/151 44/18639 0.0227272727272727 2.80538832028898 0.301153245794014 0.456171288661165 GO:0030547 signaling receptor inhibitor activity 1/151 44/18639 0.0227272727272727 2.80538832028898 0.301153245794014 0.456171288661165 GO:0140789 histone phosphatase activity 2/151 136/18639 0.0147058823529412 1.81525126606934 0.301895798380507 0.456171288661165 GO:0140303 intramembrane lipid transporter activity 1/151 45/18639 0.0222222222222222 2.74304635761589 0.306828204647744 0.456171288661165 GO:0141110 transporter inhibitor activity 1/151 45/18639 0.0222222222222222 2.74304635761589 0.306828204647744 0.456171288661165 GO:0030295 protein kinase activator activity 2/151 139/18639 0.0143884892086331 1.77607318119015 0.310854437791401 0.456171288661165 GO:0004180 carboxypeptidase activity 1/151 46/18639 0.0217391304347826 2.68341491505903 0.312457382936342 0.456171288661165 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/151 243/18639 0.0123456790123457 1.52391464311994 0.314718423430436 0.456171288661165 GO:0001784 phosphotyrosine residue binding 1/151 47/18639 0.0212765957446809 2.62632098069607 0.318041147534664 0.456171288661165 GO:0140359 ABC-type transporter activity 1/151 47/18639 0.0212765957446809 2.62632098069607 0.318041147534664 0.456171288661165 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0004711 ribosomal protein S6 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0035175 histone H3S10 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0035979 histone H2AXS139 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0044022 histone H3S28 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0044023 histone H4S1 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0044024 histone H2AS1 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0044025 histone H2BS14 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0072354 histone H3T3 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0072371 histone H2AS121 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0140823 histone H2BS36 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0140855 histone H3S57 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0140995 histone H2A kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0140997 histone H4 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0140998 histone H2B kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:1990244 histone H2AT120 kinase activity 3/151 245/18639 0.0122448979591837 1.51147452358427 0.319149830795789 0.456171288661165 GO:0004677 DNA-dependent protein kinase activity 3/151 246/18639 0.0121951219512195 1.50533031820384 0.321365964952878 0.456171288661165 GO:0140857 histone H3T45 kinase activity 3/151 246/18639 0.0121951219512195 1.50533031820384 0.321365964952878 0.456171288661165 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/151 48/18639 0.0208333333333333 2.5716059602649 0.323579862397093 0.456171288661165 GO:0038187 pattern recognition receptor activity 1/151 48/18639 0.0208333333333333 2.5716059602649 0.323579862397093 0.456171288661165 GO:0035402 histone H3T11 kinase activity 3/151 247/18639 0.0121457489878543 1.49923586347427 0.323582285767469 0.456171288661165 GO:0035403 histone H3T6 kinase activity 3/151 247/18639 0.0121457489878543 1.49923586347427 0.323582285767469 0.456171288661165 GO:0004679 AMP-activated protein kinase activity 3/151 248/18639 0.0120967741935484 1.49319055757317 0.325798718725127 0.456171288661165 GO:0008194 UDP-glycosyltransferase activity 2/151 145/18639 0.0137931034482759 1.70258049783055 0.328697925459329 0.456171288661165 GO:0001222 transcription corepressor binding 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005004 GPI-linked ephrin receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005008 hepatocyte growth factor receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005009 insulin receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005011 macrophage colony-stimulating factor receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005020 stem cell factor receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0008288 boss receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0036332 placental growth factor receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0038062 protein tyrosine kinase collagen receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0060175 brain-derived neurotrophic factor receptor activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0060590 ATPase regulator activity 1/151 49/18639 0.0204081632653061 2.51912420597378 0.329073888580624 0.456171288661165 GO:0005006 epidermal growth factor receptor activity 1/151 50/18639 0.02 2.4687417218543 0.334523584267786 0.457017282669947 GO:0005007 fibroblast growth factor receptor activity 1/151 50/18639 0.02 2.4687417218543 0.334523584267786 0.457017282669947 GO:0005017 platelet-derived growth factor receptor activity 1/151 50/18639 0.02 2.4687417218543 0.334523584267786 0.457017282669947 GO:0005019 platelet-derived growth factor beta-receptor activity 1/151 50/18639 0.02 2.4687417218543 0.334523584267786 0.457017282669947 GO:0015085 calcium ion transmembrane transporter activity 2/151 147/18639 0.0136054421768707 1.67941613731585 0.334619565497002 0.457017282669947 GO:0019209 kinase activator activity 2/151 148/18639 0.0135135135135135 1.66806873098264 0.337574845608984 0.458855009088845 GO:0005010 insulin-like growth factor receptor activity 1/151 51/18639 0.0196078431372549 2.42033502142579 0.339929304789361 0.458855009088845 GO:0005021 vascular endothelial growth factor receptor activity 1/151 51/18639 0.0196078431372549 2.42033502142579 0.339929304789361 0.458855009088845 GO:0005030 neurotrophin receptor activity 1/151 51/18639 0.0196078431372549 2.42033502142579 0.339929304789361 0.458855009088845 GO:0005080 protein kinase C binding 1/151 52/18639 0.0192307692307692 2.3737901171676 0.345291402646947 0.462485855694747 GO:0030159 signaling receptor complex adaptor activity 1/151 52/18639 0.0192307692307692 2.3737901171676 0.345291402646947 0.462485855694747 GO:0005003 ephrin receptor activity 1/151 53/18639 0.0188679245283019 2.32900162439085 0.350610227535326 0.462485855694747 GO:0005005 transmembrane-ephrin receptor activity 1/151 53/18639 0.0188679245283019 2.32900162439085 0.350610227535326 0.462485855694747 GO:0005544 calcium-dependent phospholipid binding 1/151 53/18639 0.0188679245283019 2.32900162439085 0.350610227535326 0.462485855694747 GO:0017046 peptide hormone binding 1/151 53/18639 0.0188679245283019 2.32900162439085 0.350610227535326 0.462485855694747 GO:0038064 collagen receptor activity 1/151 53/18639 0.0188679245283019 2.32900162439085 0.350610227535326 0.462485855694747 GO:0051018 protein kinase A binding 1/151 53/18639 0.0188679245283019 2.32900162439085 0.350610227535326 0.462485855694747 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/151 484/18639 0.0103305785123967 1.27517650922226 0.355436908629229 0.466785485855076 GO:0015485 cholesterol binding 1/151 54/18639 0.0185185185185185 2.28587196467991 0.355886126364669 0.466785485855076 GO:0008374 O-acyltransferase activity 1/151 55/18639 0.0181818181818182 2.24431065623119 0.361119443282556 0.470981133069926 GO:0140313 molecular sequestering activity 1/151 55/18639 0.0181818181818182 2.24431065623119 0.361119443282556 0.470981133069926 GO:0170055 lipid transmembrane transporter activity 1/151 56/18639 0.0178571428571429 2.20423368022706 0.366310519695833 0.475583891641307 GO:0001216 DNA-binding transcription activator activity 5/151 491/18639 0.010183299389002 1.25699680338814 0.366702914289302 0.475583891641307 GO:0004601 peroxidase activity 1/151 57/18639 0.0175438596491228 2.16556291390728 0.371459694292288 0.480407369992541 GO:0001786 phosphatidylserine binding 1/151 59/18639 0.0169491525423729 2.09215400157144 0.381633679319504 0.488111584323013 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/151 59/18639 0.0169491525423729 2.09215400157144 0.381633679319504 0.488111584323013 GO:0036002 pre-mRNA binding 1/151 59/18639 0.0169491525423729 2.09215400157144 0.381633679319504 0.488111584323013 GO:0045309 protein phosphorylated amino acid binding 1/151 59/18639 0.0169491525423729 2.09215400157144 0.381633679319504 0.488111584323013 GO:0015081 sodium ion transmembrane transporter activity 2/151 164/18639 0.0121951219512195 1.50533031820384 0.384249252689459 0.490103041309145 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/151 60/18639 0.0166666666666667 2.05728476821192 0.386659153723313 0.491821945532675 GO:0015026 coreceptor activity 1/151 61/18639 0.0163934426229508 2.02355878840517 0.391644054298574 0.495440429344918 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/151 61/18639 0.0163934426229508 2.02355878840517 0.391644054298574 0.495440429344918 GO:0005507 copper ion binding 1/151 63/18639 0.0158730158730159 1.9593188268685 0.401493433018159 0.506516238385307 GO:0004536 DNA nuclease activity 1/151 64/18639 0.015625 1.92870447019868 0.406358554229091 0.511260898391492 GO:0038024 cargo receptor activity 1/151 65/18639 0.0153846153846154 1.89903209373408 0.411184387785559 0.51366541731544 GO:0160215 deacylase activity 1/151 65/18639 0.0153846153846154 1.89903209373408 0.411184387785559 0.51366541731544 GO:0015291 secondary active transmembrane transporter activity 3/151 287/18639 0.0104529616724739 1.29028312988901 0.411597990980623 0.51366541731544 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/151 67/18639 0.0149253731343284 1.84234456854799 0.420719450080648 0.522476834632009 GO:0003777 microtubule motor activity 1/151 68/18639 0.0147058823529412 1.81525126606934 0.425429301633407 0.522476834632009 GO:0005548 phospholipid transporter activity 1/151 68/18639 0.0147058823529412 1.81525126606934 0.425429301633407 0.522476834632009 GO:0030145 manganese ion binding 1/151 68/18639 0.0147058823529412 1.81525126606934 0.425429301633407 0.522476834632009 GO:0032934 sterol binding 1/151 68/18639 0.0147058823529412 1.81525126606934 0.425429301633407 0.522476834632009 GO:1990841 promoter-specific chromatin binding 1/151 68/18639 0.0147058823529412 1.81525126606934 0.425429301633407 0.522476834632009 GO:0097110 scaffold protein binding 1/151 70/18639 0.0142857142857143 1.76338694418165 0.434735184016425 0.53249309576615 GO:0031625 ubiquitin protein ligase binding 3/151 302/18639 0.00993377483443709 1.22619621946406 0.443816469375029 0.542182124856566 GO:0044183 protein folding chaperone 1/151 75/18639 0.0133333333333333 1.64582781456954 0.45735001094172 0.557244881752674 GO:0017022 myosin binding 1/151 76/18639 0.0131578947368421 1.62417218543046 0.461763938346794 0.561146203292823 GO:0019199 transmembrane receptor protein kinase activity 1/151 78/18639 0.0128205128205128 1.5825267447784 0.470485078043966 0.570247620770566 GO:0016758 hexosyltransferase activity 2/151 197/18639 0.0101522842639594 1.25316838672807 0.475560408949988 0.57084151147496 GO:0030971 receptor tyrosine kinase binding 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0033192 calmodulin-dependent protein phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0140791 histone H2AXS140 phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/151 81/18639 0.0123456790123457 1.52391464311994 0.483304260255258 0.57084151147496 GO:0044389 ubiquitin-like protein ligase binding 3/151 322/18639 0.0093167701863354 1.15003496359673 0.485667930947337 0.571433936583912 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/151 82/18639 0.0121951219512195 1.50533031820384 0.487508434018672 0.571433936583912 GO:0033549 MAP kinase phosphatase activity 1/151 82/18639 0.0121951219512195 1.50533031820384 0.487508434018672 0.571433936583912 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/151 83/18639 0.0120481927710843 1.48719380834597 0.491678624591674 0.574866674711982 GO:0017018 myosin phosphatase activity 1/151 84/18639 0.0119047619047619 1.46948912015137 0.495815104850709 0.578242804901457 GO:0004518 nuclease activity 2/151 209/18639 0.00956937799043062 1.18121613485852 0.506716963107495 0.589472246027061 GO:0008081 phosphoric diester hydrolase activity 1/151 87/18639 0.0114942528735632 1.41881708152546 0.508024979963719 0.589512696048125 GO:0072341 modified amino acid binding 1/151 91/18639 0.010989010989011 1.35645149552434 0.523849046738194 0.606355271599459 GO:0052689 carboxylic ester hydrolase activity 1/151 92/18639 0.0108695652173913 1.34170745752951 0.527725410440077 0.609318865420837 GO:0051219 phosphoprotein binding 1/151 93/18639 0.010752688172043 1.32728049562059 0.531570423812781 0.612231607525666 GO:0004867 serine-type endopeptidase inhibitor activity 1/151 95/18639 0.0105263157894737 1.29933774834437 0.539167405044463 0.619440467830239 GO:0061630 ubiquitin protein ligase activity 3/151 353/18639 0.0084985835694051 1.04904039172279 0.547403181316273 0.627345725122362 GO:0042626 ATPase-coupled transmembrane transporter activity 1/151 98/18639 0.0102040816326531 1.25956210298689 0.550333981203635 0.629147242709341 GO:0008238 exopeptidase activity 1/151 102/18639 0.00980392156862745 1.21016751071289 0.564805682042489 0.644101061048454 GO:0004722 protein serine/threonine phosphatase activity 1/151 103/18639 0.00970873786407767 1.19841831157976 0.568350718564665 0.646551308834005 GO:0061659 ubiquitin-like protein ligase activity 3/151 372/18639 0.00806451612903226 0.995460371715445 0.583058741882501 0.661657346793132 GO:0005496 steroid binding 1/151 108/18639 0.00925925925925926 1.14293598233996 0.585650170242573 0.661755599284849 GO:0005539 glycosaminoglycan binding 2/151 242/18639 0.00826446280991736 1.02014120737781 0.586003878416389 0.661755599284849 GO:0004620 phospholipase activity 1/151 109/18639 0.00917431192660551 1.13245033112583 0.589026503106065 0.663550537562307 GO:0005200 structural constituent of cytoskeleton 1/151 112/18639 0.00892857142857143 1.10211684011353 0.598992390970991 0.67313950732905 GO:0019887 protein kinase regulator activity 2/151 255/18639 0.00784313725490196 0.968134008570316 0.614568273436385 0.688971212109071 GO:0032182 ubiquitin-like protein binding 1/151 120/18639 0.00833333333333333 1.02864238410596 0.624409789761239 0.696689837566376 GO:0003697 single-stranded DNA binding 1/151 121/18639 0.00826446280991736 1.02014120737781 0.627472272710969 0.696689837566376 GO:0004540 RNA nuclease activity 1/151 121/18639 0.00826446280991736 1.02014120737781 0.627472272710969 0.696689837566376 GO:0051082 unfolded protein binding 1/151 121/18639 0.00826446280991736 1.02014120737781 0.627472272710969 0.696689837566376 GO:0008528 G protein-coupled peptide receptor activity 1/151 122/18639 0.00819672131147541 1.01177939420258 0.630509948854216 0.698387814161488 GO:0016757 glycosyltransferase activity 2/151 267/18639 0.00749063670411985 0.924622367735695 0.639586109659619 0.706750283466357 GO:0004519 endonuclease activity 1/151 127/18639 0.0078740157480315 0.971945559785159 0.645333158313136 0.711402981664242 GO:0001653 peptide receptor activity 1/151 128/18639 0.0078125 0.964352235099338 0.648226130066307 0.712894770120428 GO:0016298 lipase activity 1/151 130/18639 0.00769230769230769 0.94951604686704 0.653941934511851 0.713808125020114 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/151 130/18639 0.00769230769230769 0.94951604686704 0.653941934511851 0.713808125020114 GO:0005126 cytokine receptor binding 2/151 275/18639 0.00727272727272727 0.897724262492475 0.655550495831571 0.713808125020114 GO:0005262 calcium channel activity 1/151 131/18639 0.00763358778625954 0.942267832768819 0.656765143107059 0.713808125020114 GO:0031072 heat shock protein binding 1/151 131/18639 0.00763358778625954 0.942267832768819 0.656765143107059 0.713808125020114 GO:0005179 hormone activity 1/151 132/18639 0.00757575757575758 0.935129440096328 0.659565470716246 0.715172864031901 GO:0019207 kinase regulator activity 2/151 287/18639 0.00696864111498258 0.86018875325934 0.678440186347179 0.732319638328603 GO:0140101 catalytic activity, acting on a tRNA 1/151 139/18639 0.00719424460431655 0.888036590595074 0.678542386269916 0.732319638328603 GO:0020037 heme binding 1/151 142/18639 0.00704225352112676 0.869275254174051 0.686350099805173 0.739023479557663 GO:0015293 symporter activity 1/151 146/18639 0.00684931506849315 0.845459493785721 0.696468083197318 0.74817801048807 GO:0004842 ubiquitin-protein transferase activity 3/151 449/18639 0.0066815144766147 0.824746677679612 0.708460018652963 0.759298584806301 GO:0046906 tetrapyrrole binding 1/151 152/18639 0.00657894736842105 0.812086092715232 0.711040231584208 0.760303988968795 GO:0015079 potassium ion transmembrane transporter activity 1/151 160/18639 0.00625 0.77148178807947 0.729394116507623 0.776343622857539 GO:0099106 ion channel regulator activity 1/151 160/18639 0.00625 0.77148178807947 0.729394116507623 0.776343622857539 GO:0004866 endopeptidase inhibitor activity 1/151 161/18639 0.0062111801242236 0.76668997573115 0.731605355665984 0.776911191911355 GO:0008083 growth factor activity 1/151 162/18639 0.00617283950617284 0.761957321559971 0.733798644511878 0.777457145100686 GO:0016874 ligase activity 1/151 167/18639 0.00598802395209581 0.739144228100091 0.744500860010414 0.786197102623422 GO:0016247 channel regulator activity 1/151 168/18639 0.00595238095238095 0.734744560075686 0.746589446527219 0.786197102623422 GO:0030414 peptidase inhibitor activity 1/151 169/18639 0.00591715976331361 0.730396959128492 0.748661071971125 0.786197102623422 GO:0019787 ubiquitin-like protein transferase activity 3/151 479/18639 0.00626304801670146 0.773092397240388 0.748840004874577 0.786197102623422 GO:0141108 transporter regulator activity 1/151 170/18639 0.00588235294117647 0.726100506427737 0.750715873169412 0.786383369405968 GO:0008201 heparin binding 1/151 172/18639 0.00581395348837209 0.717657477283228 0.754775544664698 0.788851190022021 GO:0005261 monoatomic cation channel activity 2/151 341/18639 0.00586510263929619 0.723971179429415 0.766539959896104 0.799342345567333 GO:0016755 aminoacyltransferase activity 3/151 496/18639 0.00604838709677419 0.746595278786584 0.769682674237258 0.79973167894075 GO:0016853 isomerase activity 1/151 180/18639 0.00555555555555556 0.685761589403973 0.770367880793897 0.79973167894075 GO:0061135 endopeptidase regulator activity 1/151 184/18639 0.00543478260869565 0.670853728764757 0.777790611030134 0.805630990843293 GO:0140597 protein carrier chaperone 1/151 188/18639 0.00531914893617021 0.656580245174017 0.784974943463804 0.811257586660136 GO:0008236 serine-type peptidase activity 1/151 194/18639 0.00515463917525773 0.636273639653171 0.795321020992082 0.82011944926355 GO:0017171 serine hydrolase activity 1/151 198/18639 0.00505050505050505 0.623419626730885 0.801942115265977 0.824826579760627 GO:0046982 protein heterodimerization activity 2/151 369/18639 0.00542005420054201 0.669035696979486 0.803448785036809 0.824826579760627 GO:0140098 catalytic activity, acting on RNA 2/151 387/18639 0.00516795865633075 0.637917757585092 0.824371006955294 0.844433133230755 GO:0061134 peptidase regulator activity 1/151 226/18639 0.00442477876106195 0.546181796870421 0.84269692141392 0.861299502460584 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/151 229/18639 0.00436681222707424 0.539026576824084 0.846535477286101 0.862700474841323 GO:0000287 magnesium ion binding 1/151 230/18639 0.00434782608695652 0.536682983011805 0.847794203137801 0.862700474841323 GO:0016887 ATP hydrolysis activity 2/151 417/18639 0.00479616306954436 0.592024393730049 0.854854139912467 0.867976900832176 GO:0140104 molecular carrier activity 1/151 249/18639 0.00401606425702811 0.495731269448655 0.869852778041243 0.881273164623842 GO:0005216 monoatomic ion channel activity 2/151 448/18639 0.00446428571428571 0.551058420056764 0.881243057368198 0.888844186439005 GO:0046873 metal ion transmembrane transporter activity 2/151 450/18639 0.00444444444444444 0.548609271523179 0.882784593272231 0.888844186439005 GO:0003730 mRNA 3'-UTR binding 1/151 262/18639 0.00381679389312977 0.471133916384409 0.883084936850847 0.888844186439005 GO:0008514 organic anion transmembrane transporter activity 1/151 269/18639 0.00371747211895911 0.458873925995224 0.889647135678099 0.893506776179957 GO:1901681 sulfur compound binding 1/151 275/18639 0.00363636363636364 0.448862131246237 0.894979774202384 0.896916959860831 GO:0140097 catalytic activity, acting on DNA 1/151 336/18639 0.00297619047619048 0.367372280037843 0.936586786973701 0.936586786973701