category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	8/70	133/9376	8.05671321160043	HLA-B/HLA-A/PRF1/HLA-C/PRKCB/LCP2/LCK/CD244	7.1084505389767
Human Diseases	Immune disease	hsa05330	Allograft rejection	5/70	39/9376	17.1721611721612	HLA-B/HLA-A/PRF1/HLA-C/HLA-DRB5	8.77707519558152
NA	NA	hsa04517	IgSF CAM signaling	11/70	299/9376	4.92766364070712	CD96/PRKCB/MYL9/FOXO1/MBP/LCP2/LCK/ACTB/MYL6/CD244/CD2	5.9862086330013
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	6/70	70/9376	11.4808163265306	HLA-B/HLA-A/PRF1/HLA-C/HLA-DRB5/ACTB	7.63335991863268
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	5/70	44/9376	15.2207792207792	HLA-B/HLA-A/PRF1/HLA-C/HLA-DRB5	8.20003113346542
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	5/70	45/9376	14.8825396825397	HLA-B/HLA-A/PRF1/HLA-C/HLA-DRB5	8.09588293715545
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	9/70	224/9376	5.38163265306122	B2M/HLA-B/HLA-A/HLA-C/HLA-DRB5/CD3E/CD3D/LCK/IL2RB	5.75645484044584
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	5/70	54/9376	12.4021164021164	HLA-B/HLA-A/PRF1/HLA-C/HLA-DRB5	7.28753972324379
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	8/70	205/9376	5.22703832752613	B2M/HLA-B/HLA-A/HLA-C/HLA-DRB5/CD3E/CD3D/ISG15	5.3071077307565
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	4/70	38/9376	14.0992481203008	PTPRC/CD3E/CD3D/LCK	7.01720826226375
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	6/70	116/9376	6.92807881773399	RHOH/PRKCB/MYL9/ITK/ACTB/MMP2	5.57173695098421
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	6/70	122/9376	6.58735362997658	PTPRC/ITK/CD3E/CD3D/LCP2/LCK	5.38734094214389
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	5/70	82/9376	8.16724738675958	B2M/HLA-B/HLA-A/HLA-C/HLA-DRB5	5.65341831063324
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	5/70	93/9376	7.20122887864823	HLA-DRB5/CD3E/CD3D/LCK/IL2RB	5.21228547687657
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/70	204/9376	4.59607843137255	LUM/DCN/PRKCB/TIMP3/FN1/ACTB/MMP2	4.50365744525299
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	5/70	100/9376	6.69714285714286	CD9/HLA-DRB5/CD3E/CD3D/CD2	4.96740847287989
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/70	155/9376	5.18488479262673	HLA-B/HLA-A/CORO1A/HLA-C/HLA-DRB5/ACTB	4.55631224598027
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	7/70	214/9376	4.38130841121495	B2M/HLA-B/HLA-A/HLA-C/PRKCB/CD3E/CD3D	4.33959961404641
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	6/70	160/9376	5.02285714285714	HLA-B/HLA-A/HLA-C/PTPRC/HLA-DRB5/CD2	4.45119379448985
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/70	109/9376	6.14416775884666	HLA-DRB5/CD3E/CD3D/LCK/IL2RB	4.68502512949186
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	6/70	180/9376	4.4647619047619	B2M/HLA-B/HLA-A/HLA-C/HLA-DRB5/CCL5	4.07064567212409
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	5/70	138/9376	4.85300207039337	FN1/LCP2/LCK/ACTB/WIPF1	3.95460344845265
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/70	157/9376	4.26569608735214	HLA-B/HLA-A/HLA-C/FOXO1/IGFBP3	3.57879497382668
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/70	101/9376	5.3046676096181	PRKCB/FOXO1/FN1/MMP2	3.77221540523985
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/70	227/9376	3.54033983637508	B2M/HLA-B/HLA-A/HLA-C/PRKCB/CCL5	3.36024595964725
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	4/70	134/9376	3.99829424307036	PRKCB/MYL9/RAMP1/MYL6	3.03177384561414
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/70	137/9376	3.91074035453597	PRF1/PTPN13/ACTB/CTSW	2.97648981711379
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/70	212/9376	3.15902964959569	SKAP1/CNR1/PRKCB/LCP2/ACTB	2.75763721139207
Human Diseases	Immune disease	hsa05310	Asthma	2/70	32/9376	8.37142857142857	PRG2/HLA-DRB5	3.62254150440501
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/70	154/9376	3.47903525046382	PRKCB/MYL9/ACTB/MYL6	2.69019423586317
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/70	90/9376	4.4647619047619	CD3E/CD3D/LCK	2.86439854744233
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	5/70	233/9376	2.87431023911711	DCN/SYNE1/MYL9/FN1/ACTB	2.51262810013071
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/70	238/9376	2.81392557022809	CFD/PRKCB/RPL13/ISG15/RPS9	2.45830349565076
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	6/70	333/9376	2.41338481338481	HLA-B/HLA-A/HLA-C/FOXO1/FN1/ISG15	2.27761023637074
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/70	100/9376	4.01828571428571	IL2RB/CCL21/CCL5	2.63168019596305
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	5/70	250/9376	2.67885714285714	HLA-B/HLA-A/HLA-C/WIPF1/IL2RB	2.33344005744311
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	4/70	173/9376	3.09694467382329	PRKCB/HLA-DRB5/ACTB/CCL5	2.41434009494566
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/70	253/9376	2.64709203839639	MYL9/FOXO1/FNBP1/ACTB/CCL5	2.3033632063925
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/70	103/9376	3.90124826629681	CD3E/CD3D/CCL5	2.56771318111142
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/70	105/9376	3.8269387755102	PRKCB/LCK/CCL21	2.52639292210152
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/70	193/9376	2.7760177646188	PRKCB/ITK/CCL21/CCL5	2.16215488861405
Cellular Processes	Cell motility	hsa04814	Motor proteins	4/70	194/9376	2.76170839469809	MYL9/MYO1F/ACTB/MYL6	2.15040063022607
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/70	122/9376	3.29367681498829	PRKCB/FOXO1/ACTB	2.2115691670449
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/70	201/9376	2.66552949538024	FOXO1/ZBTB16/IGFBP3/IL2RB	2.07014351528492
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/70	203/9376	2.63926812104152	PRKCB/MYL9/FN1/ACTB	2.04783730187809
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/70	298/9376	2.24736337488015	PRL/TNFRSF18/IL2RB/CCL21/CCL5	1.89783811758268
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/70	136/9376	2.9546218487395	CD3E/CD3D/IL2RB	1.99135803924054
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/70	232/9376	2.30935960591133	TMSB4X/MYL9/FN1/ACTB	1.75141053026967
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/70	15/9376	8.92952380952381	ST3GAL5	2.66553720378822
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/70	76/9376	3.52481203007519	PRKCB/ACTB	1.91667071293581
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	4/70	248/9376	2.16036866359447	RHOH/PTPRC/MYL9/ACTB	1.60615387838953
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/70	78/9376	3.43443223443223	FN1/ACTB	1.87242035825334
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/70	78/9376	3.43443223443223	PRKCB/HLA-DRB5	1.87242035825334
Metabolism	Lipid metabolism	hsa00120	Primary bile acid biosynthesis	1/70	17/9376	7.87899159663866	CYP8B1	2.46199774080996
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/70	170/9376	2.3636974789916	MYL9/ACTB/MYL6	1.55618113835444
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/70	88/9376	3.04415584415584	CFD/SERPINE2	1.67088811410112
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/70	93/9376	2.88049155145929	MYL9/ACTB	1.58059942551209
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/70	93/9376	2.88049155145929	PRKCB/MMP2	1.58059942551209
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/70	95/9376	2.81984962406015	HLA-DRB5/CCL5	1.5461550872105
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/70	187/9376	2.14881588999236	TXNIP/CCL5/P2RX7	1.37622754377133
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/70	98/9376	2.733527696793	PRKCB/PTPRC	1.49613152028823
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/70	99/9376	2.70591630591631	CFD/HLA-DRB5	1.47987377308506
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/70	103/9376	2.60083217753121	PRKCB/FN1	1.41679632547988
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/70	196/9376	2.05014577259475	HLA-B/HLA-A/HLA-C	1.28857415854996
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/70	200/9376	2.00914285714286	MYO1F/ACTB/WIPF1	1.25110592274173
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/70	109/9376	2.45766710353866	PRKCB/FOXO1	1.32756304433652
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/70	205/9376	1.9601393728223	HLA-B/HLA-A/HLA-C	1.20546886337108
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/70	110/9376	2.43532467532468	PRKCB/TIMP1	1.31326835607911
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/70	122/9376	2.19578454332553	PRKCB/IGFBP3	1.15297857534524
Organismal Systems	Immune system	hsa04611	Platelet activation	2/70	126/9376	2.12607709750567	LCP2/ACTB	1.10366092341484
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/70	37/9376	3.62007722007722	PRKCB	1.384898355838
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/70	38/9376	3.52481203007519	NNMT	1.35253044109067
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/70	38/9376	3.52481203007519	PRKCB	1.35253044109067
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/70	41/9376	3.26689895470383	MMP2	1.26159530334807
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/70	42/9376	3.1891156462585	FTL	1.23314056967425
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/70	142/9376	1.88651911468813	LCP2/LCK	0.923188689954174
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/70	142/9376	1.88651911468813	ACTB/MMP2	0.923188689954174
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/70	46/9376	2.91180124223602	FTL	1.12728562128721
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/70	46/9376	2.91180124223602	PSMB8	1.12728562128721
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/70	370/9376	1.44803088803089	PRL/CNR1/TAC3/P2RX7	0.762598560016117
NA	NA	hsa03272	Virion - Hepatitis viruses	1/70	48/9376	2.79047619047619	CD9	1.07856924971622
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/70	48/9376	2.79047619047619	PRKCB	1.07856924971622
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/70	149/9376	1.79789069990412	CNR1/PRKCB	0.851450512132626
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/70	50/9376	2.67885714285714	HLA-DRB5	1.03229583116653
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/70	51/9376	2.62633053221289	ACTB	1.01000289194276
NA	NA	hsa04518	Integrin signaling	2/70	154/9376	1.73951762523191	FN1/ACTB	0.802508174236686
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/70	53/9376	2.52722371967655	PRKCB	0.966976427909355
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/70	168/9376	1.59455782312925	PRL/IL2RB	0.67440257143795
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/70	60/9376	2.23238095238095	PRKCB	0.830537022595639
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/70	60/9376	2.23238095238095	PRKCB	0.830537022595639
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/70	170/9376	1.57579831932773	PRKCB/ACTB	0.657071306384312
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/70	61/9376	2.19578454332553	FTL	0.812605125748885
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/70	62/9376	2.16036866359447	FOXO1	0.795017802944912
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/70	178/9376	1.50497592295345	DKK1/PRKCB	0.589911828290571
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/70	65/9376	2.06065934065934	PRKCB	0.744196408912375
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/70	66/9376	2.02943722943723	HSD11B1	0.727863818964418
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/70	66/9376	2.02943722943723	HLA-DRB5	0.727863818964418
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/70	181/9376	1.48003157063931	CORO1A/HLA-DRB5	0.565569988180946
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/70	67/9376	1.99914712153518	PRKCB	0.711817173743411
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/70	68/9376	1.96974789915966	DHRS3	0.696046494512176
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/70	68/9376	1.96974789915966	ZBTB16	0.696046494512176
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/70	69/9376	1.94120082815735	LCP2	0.680542297862738
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/70	69/9376	1.94120082815735	PRKCB	0.680542297862738
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/70	70/9376	1.9134693877551	HSD11B1	0.665295564214501
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/70	71/9376	1.88651911468813	PRL	0.650297708738847
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/70	71/9376	1.88651911468813	CCL5	0.650297708738847
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/70	72/9376	1.86031746031746	ISG15	0.635540554491766
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/70	73/9376	1.83483365949119	PRKCB	0.621016307558491
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/70	195/9376	1.37377289377289	PRKCB/ACTB	0.45743906359772
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/70	75/9376	1.78590476190476	IGFBP3	0.592637138680843
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/70	75/9376	1.78590476190476	PRKCB	0.592637138680843
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/70	76/9376	1.76240601503759	CYP8B1	0.578768345121178
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/70	76/9376	1.76240601503759	PRKCB	0.578768345121178
NA	NA	hsa04082	Neuroactive ligand signaling	2/70	199/9376	1.34615936826992	PRKCB/TAC3	0.428060738177869
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/70	79/9376	1.69547920433996	HSD11B1	0.538368216780178
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/70	80/9376	1.67428571428571	PRKCB	0.525283826050388
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/70	205/9376	1.30675958188153	PRKCB/MMP2	0.385141089893998
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/70	83/9376	1.61376936316695	CCL5	0.487101445280493
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/70	86/9376	1.55747508305648	PRKCB	0.450422382691123
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/70	86/9376	1.55747508305648	PRKCB	0.450422382691123
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/70	86/9376	1.55747508305648	ACTB	0.450422382691123
NA	NA	hsa04382	Cornified envelope formation	2/70	217/9376	1.23449637919684	S100A4/S100A6	0.303106404415653
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/70	89/9376	1.50497592295345	FN1	0.415127100679665
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/70	89/9376	1.50497592295345	PRKCB	0.415127100679665
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/70	89/9376	1.50497592295345	PRKCB	0.415127100679665
NA	NA	hsa04081	Hormone signaling	2/70	219/9376	1.2232224396608	PRL/RAMP1	0.289892136347925
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/70	90/9376	1.48825396825397	FOXO1	0.403650812348021
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/70	91/9376	1.47189952904239	PRKCB	0.392312747650407
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/70	91/9376	1.47189952904239	PRKCB	0.392312747650407
Genetic Information Processing	Translation	hsa03010	Ribosome	2/70	222/9376	1.20669240669241	RPL13/RPS9	0.270301645433494
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/70	93/9376	1.44024577572965	PRKCB	0.370037408390593
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/70	93/9376	1.44024577572965	FN1	0.370037408390593
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/70	362/9376	1.11002367797948	PRL/FN1/IL2RB	0.185154725857994
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/70	97/9376	1.38085419734904	PRKCB	0.326999553867905
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/70	98/9376	1.3667638483965	PRKCB	0.316537748490176
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/70	98/9376	1.3667638483965	PRKCB	0.316537748490176
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/70	99/9376	1.35295815295815	MMP2	0.306189413717311
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/70	99/9376	1.35295815295815	PRKCB	0.306189413717311
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/70	99/9376	1.35295815295815	PRKCB	0.306189413717311
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/70	99/9376	1.35295815295815	ACTB	0.306189413717311
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/70	235/9376	1.13993920972644	CNR1/ACTB	0.188421140309379
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/70	101/9376	1.32616690240453	PRKCB	0.285822722103013
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/70	238/9376	1.12557022809124	PRKCB/RASAL3	0.170177727097995
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/70	102/9376	1.31316526610644	PRKCB	0.275799364825724
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/70	105/9376	1.2756462585034	ACTB	0.246340940426301
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/70	106/9376	1.26361185983827	FOXO1	0.236717924765647
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/70	107/9376	1.25180240320427	FOXO1	0.227189602964275
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/70	109/9376	1.22883355176933	CCL5	0.208409015951408
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/70	110/9376	1.21766233766234	DCN	0.19915289221757
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/70	254/9376	1.05466816647919	PRKCB/P2RX7	0.0766054144894877
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/70	112/9376	1.19591836734694	HLA-DRB5	0.180899774404617
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/70	115/9376	1.16472049689441	PRKCB	0.154141917020838
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/70	115/9376	1.16472049689441	PRKCB	0.154141917020838
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/70	115/9376	1.16472049689441	PRKCB	0.154141917020838
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/70	116/9376	1.15467980295567	PRKCB	0.145381868257358
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/70	117/9376	1.14481074481074	ACTB	0.136698834005827
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/70	119/9376	1.12557022809124	CCL5	0.119557869136287
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/70	122/9376	1.09789227166276	FOXO1	0.0943879836455758
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/70	125/9376	1.07154285714286	PRKCB	0.0698361164247561
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/70	130/9376	1.03032967032967	MMP2	0.0302005989024077
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/70	133/9376	1.00708915145005	FOXO1	0.00714112660313043
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/70	133/9376	1.00708915145005	PRKCB	0.00714112660313043
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/70	138/9376	0.970600414078675	FOXO1	-0.0301748355550927
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/70	139/9376	0.963617677286742	MMP2	-0.0374787833468499
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/70	143/9376	0.936663336663337	HLA-DRB5	-0.0661919103679093
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/70	300/9376	0.892952380952381	PRKCB/PTPN7	-0.163434421463178
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/70	144/9376	0.93015873015873	FOXO1	-0.0732484787065737
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/70	144/9376	0.93015873015873	PRKCB	-0.0732484787065737
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/70	154/9376	0.869758812615955	DHRS3	-0.141334856576556
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/70	157/9376	0.853139217470428	MFGE8	-0.160941072381061
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/70	157/9376	0.853139217470428	ACTB	-0.160941072381061
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/70	158/9376	0.847739602169982	PRKCB	-0.167398008080356
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/70	323/9376	0.82936753648828	PRKCB/TIMP3	-0.270657331750174
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/70	163/9376	0.821735319894829	PRKCB	-0.199118542599417
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/70	166/9376	0.806884681583477	MYL9	-0.217717875378448
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/70	168/9376	0.797278911564626	FTL	-0.229945041520033
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/70	184/9376	0.727950310559006	MYL9	-0.323225244203478
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	2/70	388/9376	0.690427098674521	DKK1/APBB1	-0.540132615284112
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/70	216/9376	0.62010582010582	CCL5	-0.489885869813219
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/70	217/9376	0.61724818959842	PRKCB	-0.494739089071479
NA	NA	hsa04519	Cadherin signaling	2/70	404/9376	0.663083451202263	MYO1F/ACTB	-0.600373517930507
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/70	226/9376	0.592667509481669	MYL9	-0.53758341179694
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/70	250/9376	0.535771428571429	CTSW	-0.645230327660579
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/70	275/9376	0.487064935064935	CCL5	-0.74875082320739
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	2/70	480/9376	0.558095238095238	DKK1/PRKCB	-0.86199559634685
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/70	368/9376	0.363975155279503	ACTB	-1.07953551698128