category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	4/39	50/9376	19.2328205128205	HBB/HBA2/HBA1/PECAM1	8.35421053282568
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	5/39	155/9376	7.75516956162117	ITGB5/HLA-B/CYBA/HLA-DRB1/TCIRG1	5.48059051943707
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/39	37/9376	19.4927234927235	HBB/HBA2/HBA1	7.28393082518735
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/39	181/9376	6.64116730415073	ITGAX/CD74/KSR1/HLA-DRB1/TCIRG1	4.95275292410197
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/39	232/9376	5.18125552608311	PFN1/TMSB4X/ITGB5/ITGAX/ARHGEF1	4.1677038883514
NA	NA	hsa04518	Integrin signaling	4/39	154/9376	6.24442224442224	SPP1/FRAS1/ITGB5/ITGAX	4.24091643091942
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/39	160/9376	6.01025641025641	PECAM1/HLA-B/PTPRD/HLA-DRB1	4.13107398462381
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/39	82/9376	8.79549718574109	HLA-B/CD74/HLA-DRB1	4.58209061518887
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	3/39	89/9376	8.10371650821089	SPP1/FRAS1/ITGB5	4.3516821268258
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/39	95/9376	7.5919028340081	LTB/HLA-DRB1/TCIRG1	4.17339484977506
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/39	39/9376	12.3287310979619	HLA-B/HLA-DRB1	4.58167368578416
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/39	44/9376	10.9277389277389	HLA-B/HLA-DRB1	4.26583038540609
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/39	45/9376	10.6849002849003	HLA-B/HLA-DRB1	4.20873496634893
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/39	142/9376	5.07908992416035	LILRB1/CYBA/JUNB	3.16538674119094
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/39	54/9376	8.90408357075024	HLA-B/HLA-DRB1	3.76450706357153
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	2/39	59/9376	8.14950021729683	ENTPD1/NT5C	3.56022875938567
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/39	70/9376	6.86886446886447	HLA-B/HLA-DRB1	3.18519363043278
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/39	180/9376	4.00683760683761	HLA-B/CD74/HLA-DRB1	2.63245530902033
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/39	78/9376	6.16436554898093	CYBA/HLA-DRB1	2.95994586374129
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/39	333/9376	2.88781088781089	SPP1/ITGB5/HLA-B/TCIRG1	2.26693255931462
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	2/39	85/9376	5.65671191553544	ENTPD1/NT5C	2.7872239590205
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/39	205/9376	3.51819887429644	ENTPD1/HLA-B/HLA-DRB1	2.35598690138522
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/39	212/9376	3.40203193033382	EFNA5/PFN1/SKAP1	2.28622215333833
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/39	109/9376	4.41119736532581	RUNX1/HLA-DRB1	2.31507346587179
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/39	116/9376	4.14500442086649	PECAM1/CYBA	2.20271862434689
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/39	128/9376	3.75641025641026	ENTPD1/NT5C	2.02926700422198
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/39	28/9376	8.58608058608059	TCIRG1	2.59807316970621
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/39	142/9376	3.38605994944023	PECAM1/CYBA	1.85159010173072
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	1/39	30/9376	8.01367521367521	IDH2	2.48660986465192
Human Diseases	Immune disease	hsa05310	Asthma	1/39	32/9376	7.51282051282051	HLA-DRB1	2.38501956580127
NA	NA	hsa04517	IgSF CAM signaling	3/39	299/9376	2.41214304090558	ITGAX/PTPRD/SLAMF7	1.6038264773224
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/39	33/9376	7.28515928515929	IDH2	2.33746085379466
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/39	157/9376	3.06255103707333	PECAM1/ITGB5	1.68432883961139
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/39	38/9376	6.32658569500675	NT5C	2.12631716074797
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/39	42/9376	5.72405372405372	FTH1	1.98298686353856
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/39	46/9376	5.2263099219621	FTH1	1.85700767063844
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/39	50/9376	4.80820512820513	HLA-DRB1	1.74490542320874
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/39	362/9376	1.99235019124522	EFNA5/SPP1/ITGB5	1.2444421956614
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/39	51/9376	4.71392659627954	TCIRG1	1.71873232891799
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/39	195/9376	2.46574621959237	CYBA/HDAC10	1.33673511577493
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/39	203/9376	2.36857395478085	SPP1/ITGB5	1.27401592084086
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/39	204/9376	2.35696329813977	ITGB5/ARHGEF1	1.26638402795333
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/39	205/9376	2.34546591619762	HLA-B/HDAC10	1.25879655780067
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/39	59/9376	4.07475010864841	IDH2	1.53112992964887
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/39	61/9376	3.94115174443043	FTH1	1.48937884912047
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/39	216/9376	2.22602089268756	CYBA/ARHGEF1	1.17812472939484
Genetic Information Processing	Translation	hsa03010	Ribosome	2/39	222/9376	2.16585816585817	RPL13/RPS2	1.13613781330477
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/39	65/9376	3.69861932938856	DGKG	1.41095903236603
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/39	65/9376	3.69861932938856	SPP1	1.41095903236603
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/39	224/9376	2.14652014652015	HLA-B/HLA-DRB1	1.12243695328134
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/39	66/9376	3.64257964257964	HLA-DRB1	1.3923213240701
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/39	227/9376	2.11815203885688	HLA-B/ARHGEF1	1.1021513505001
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/39	68/9376	3.53544494720965	CYP26A1	1.35610936896128
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/39	68/9376	3.53544494720965	RUNX1	1.35610936896128
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/39	70/9376	3.43443223443223	EGLN3	1.32123310871653
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/39	71/9376	3.38605994944023	TCIRG1	1.30426727903132
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/39	71/9376	3.38605994944023	IDH2	1.30426727903132
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/39	238/9376	2.02025425554837	EFNA5/KSR1	1.0303519062002
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/39	238/9376	2.02025425554837	RPL13/RPS2	1.0303519062002
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/39	75/9376	3.20547008547009	IDH2	1.23931367905581
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/39	77/9376	3.12221112221112	RUNX1	1.20845389914154
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/39	79/9376	3.04316780266147	TCIRG1	1.17858369501606
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/39	83/9376	2.89650911337658	IDH2	1.12158004530386
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/39	86/9376	2.79546809779368	ITGB5	1.08101899167904
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/39	88/9376	2.73193473193473	ITGAX	1.05493576580564
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/39	91/9376	2.64187094956326	LILRB1	1.01714536209945
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/39	93/9376	2.58505652054039	HLA-DRB1	0.992787532050078
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/39	98/9376	2.45316588173731	DGKG	0.934577473330992
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/39	99/9376	2.42838642838643	HLA-DRB1	0.923365824504619
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/39	99/9376	2.42838642838643	DGKG	0.923365824504619
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/39	99/9376	2.42838642838643	ITGB5	0.923365824504619
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/39	100/9376	2.40410256410256	HLA-DRB1	0.912289601636319
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/39	298/9376	1.61349165376011	TNFRSF18/LTB	0.695562186307259
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/39	104/9376	2.31163708086785	DGKG	0.869276434695947
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/39	105/9376	2.28962148962149	LTB	0.858831337251681
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/39	105/9376	2.28962148962149	KSR1	0.858831337251681
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/39	105/9376	2.28962148962149	ITGB5	0.858831337251681
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/39	109/9376	2.2055986826629	SPP1	0.818202297261769
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/39	110/9376	2.18554778554779	EGLN3	0.80832036493243
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/39	112/9376	2.14652014652015	HLA-DRB1	0.788870454843714
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/39	115/9376	2.09052396878484	ARHGEF1	0.760447884087987
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/39	116/9376	2.07250221043325	IDH2	0.75116606447365
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/39	119/9376	2.02025425554837	JUNB	0.723870746580553
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/39	122/9376	1.97057587221522	JUNB	0.69736303157394
Organismal Systems	Immune system	hsa04611	Platelet activation	1/39	126/9376	1.90801790801791	ARHGEF1	0.663167267601572
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/39	133/9376	1.80759591285907	HLA-B	0.606216452294071
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/39	134/9376	1.79410639112132	ARHGEF1	0.598359748163839
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/39	138/9376	1.7421033073207	TCIRG1	0.567582757544866
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/39	138/9376	1.7421033073207	ARHGEF1	0.567582757544866
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/39	140/9376	1.71721611721612	SPP1	0.552568798716386
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/39	142/9376	1.69302997472012	HERC1	0.53779346227051
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/39	143/9376	1.68119060426753	HLA-DRB1	0.530492822496009
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/39	149/9376	1.61349165376011	DGKG	0.487849422204016
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/39	157/9376	1.53127551853667	HLA-B	0.433852380652139
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/39	168/9376	1.43101343101343	FTH1	0.364314998827837
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/39	170/9376	1.41417797888386	RUNX1	0.352200722238523
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/39	173/9376	1.38965466133096	HLA-DRB1	0.334312394980676
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/39	184/9376	1.30657748049052	EFNA5	0.271430356287127
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/39	187/9376	1.28561634443987	CYBA	0.254967013043755
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/39	191/9376	1.25869244193852	HDAC10	0.23343990939883
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/39	196/9376	1.22658294086866	HLA-B	0.207180161220195
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/39	200/9376	1.20205128205128	ARHGEF1	0.186665547374274
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/39	201/9376	1.19607092741421	RUNX1	0.18160276542134
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/39	205/9376	1.17273295809881	CYBA	0.161606214216112
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/39	214/9376	1.12341241313204	HLA-B	0.1180279460767
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/39	227/9376	1.05907601942844	CYBA	0.0582306451471415
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/39	233/9376	1.0318036755805	ITGB5	0.0317705825102154
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/39	248/9376	0.969396195202647	PFN1	-0.0315665929598913
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/39	250/9376	0.961641025641026	TCIRG1	-0.0397293098564775
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/39	250/9376	0.961641025641026	HLA-B	-0.0397293098564775
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/39	253/9376	0.950238167629472	PFN1	-0.051856362472295
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/39	275/9376	0.874219114219114	CYBA	-0.136820351196539
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/39	300/9376	0.801367521367521	EFNA5	-0.225984112649113
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/39	323/9376	0.744304199412559	EFNA5	-0.302233679721011
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/39	368/9376	0.653288740245262	PFN1	-0.438522547998539
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/39	370/9376	0.64975744975745	GZMA	-0.444240408194354
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/39	449/9376	0.535434869510593	OR5V1	-0.651975497883343