ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	44/535	489/18639	0.0899795501022495	3.13482025113239	2.10363820896136e-11	9.99251777832847e-09
GO:0060589	nucleoside-triphosphatase regulator activity	44/535	490/18639	0.0897959183673469	3.12842265878314	2.2505670671911e-11	9.99251777832847e-09
GO:0005096	GTPase activator activity	29/535	271/18639	0.107011070110701	3.72818567438011	1.21233592197069e-09	3.58851432903325e-07
GO:0035091	phosphatidylinositol binding	26/535	284/18639	0.0915492957746479	3.18950901671713	2.09326348992147e-07	4.64704494762567e-05
GO:0005543	phospholipid binding	31/535	497/18639	0.062374245472837	2.17307207732376	4.75489226623597e-05	0.00844468866483509
GO:1901981	phosphatidylinositol phosphate binding	16/535	185/18639	0.0864864864864865	3.01312452639555	9.01119432136264e-05	0.0133365675956167
GO:0005085	guanyl-nucleotide exchange factor activity	18/535	230/18639	0.0782608695652174	2.7265501828525	0.000121790636878479	0.0154500122211556
GO:0034987	immunoglobulin receptor binding	5/535	19/18639	0.263157894736842	9.16822429906542	0.000159235901304388	0.017675185044787
GO:0031267	small GTPase binding	20/535	283/18639	0.0706713780918728	2.46213797430732	0.000208770517289544	0.020598691039235
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/535	21/18639	0.238095238095238	8.29506008010681	0.000265735220918861	0.0230823010155169
GO:0051020	GTPase binding	21/535	315/18639	0.0666666666666667	2.32261682242991	0.000323441606297184	0.0230823010155169
GO:0008093	cytoskeletal anchor activity	5/535	22/18639	0.227272727272727	7.91801189464741	0.00033582962269199	0.0230823010155169
GO:0019905	syntaxin binding	8/535	61/18639	0.131147540983607	4.5690822736326	0.000337916568920855	0.0230823010155169
GO:0038024	cargo receptor activity	8/535	65/18639	0.123076923076923	4.2879079798706	0.000524019946032198	0.0332378365768994
GO:0000149	SNARE binding	10/535	106/18639	0.0943396226415094	3.28672191853289	0.000944273831253216	0.0540005498827526
GO:0005516	calmodulin binding	15/535	207/18639	0.072463768115942	2.5245835026412	0.000972982880770317	0.0540005498827526
GO:0099604	ligand-gated calcium channel activity	5/535	29/18639	0.172413793103448	6.00676764421528	0.00128332736080655	0.0640596936710575
GO:0043178	alcohol binding	9/535	92/18639	0.0978260869565217	3.40818772856562	0.00129850730414306	0.0640596936710575
GO:0001786	phosphatidylserine binding	7/535	59/18639	0.11864406779661	4.13347061618882	0.0014470748138044	0.066781845952314
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/535	30/18639	0.166666666666667	5.80654205607477	0.00150409562955662	0.066781845952314
GO:0004715	non-membrane spanning protein tyrosine kinase activity	6/535	45/18639	0.133333333333333	4.64523364485981	0.00171159089830353	0.070979054413212
GO:0001221	transcription coregulator binding	10/535	115/18639	0.0869565217391304	3.02950020316944	0.00175849008681381	0.070979054413212
GO:0004713	protein tyrosine kinase activity	11/535	140/18639	0.0785714285714286	2.73736982643525	0.00238374970373057	0.0862121256863035
GO:0005031	tumor necrosis factor receptor activity	3/535	10/18639	0.3	10.4517757009346	0.00242714317810539	0.0862121256863035
GO:0031720	haptoglobin binding	3/535	10/18639	0.3	10.4517757009346	0.00242714317810539	0.0862121256863035
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/535	67/18639	0.104477611940299	3.63992188589761	0.00303157645836127	0.103539995962493
GO:0005272	sodium channel activity	6/535	51/18639	0.117647058823529	4.09873556899395	0.00327516060684277	0.104585983687334
GO:0032934	sterol binding	7/535	68/18639	0.102941176470588	3.58639362286971	0.00329775624239341	0.104585983687334
GO:0015085	calcium ion transmembrane transporter activity	11/535	147/18639	0.0748299319727891	2.60701888231928	0.00347927130417705	0.106537686831353
GO:0043274	phospholipase binding	4/535	23/18639	0.173913043478261	6.05900040633889	0.00385078750390563	0.112075721597841
GO:0005496	steroid binding	9/535	108/18639	0.0833333333333333	2.90327102803738	0.00391255334406877	0.112075721597841
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/535	12/18639	0.25	8.70981308411215	0.00426327568847394	0.113985479832418
GO:0015485	cholesterol binding	6/535	54/18639	0.111111111111111	3.87102803738318	0.00437026966961949	0.113985479832418
GO:0003823	antigen binding	12/535	174/18639	0.0689655172413793	2.40270705768611	0.00451542656663253	0.113985479832418
GO:0005262	calcium channel activity	10/535	131/18639	0.0763358778625954	2.65948491117928	0.00454025745754533	0.113985479832418
GO:0072341	modified amino acid binding	8/535	91/18639	0.0879120879120879	3.06279141419328	0.00462103296617912	0.113985479832418
GO:0003707	nuclear steroid receptor activity	4/535	25/18639	0.16	5.57428037383178	0.00525783908015	0.121906650301247
GO:0005035	death receptor activity	3/535	13/18639	0.230769230769231	8.03982746225737	0.00542514111163881	0.121906650301247
GO:0017154	semaphorin receptor activity	3/535	13/18639	0.230769230769231	8.03982746225737	0.00542514111163881	0.121906650301247
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/535	40/18639	0.125	4.35490654205607	0.00549129055411023	0.121906650301247
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/535	41/18639	0.121951219512195	4.248689309323	0.00610942200835485	0.132321140083393
GO:0005344	oxygen carrier activity	3/535	14/18639	0.214285714285714	7.46555407209613	0.00675903561183739	0.133463531885937
GO:0005545	1-phosphatidylinositol binding	3/535	14/18639	0.214285714285714	7.46555407209613	0.00675903561183739	0.133463531885937
GO:0019763	immunoglobulin receptor activity	3/535	14/18639	0.214285714285714	7.46555407209613	0.00675903561183739	0.133463531885937
GO:0004879	nuclear receptor activity	6/535	59/18639	0.101694915254237	3.54297481387613	0.00676335465638195	0.133463531885937
GO:0042626	ATPase-coupled transmembrane transporter activity	8/535	98/18639	0.0816326530612245	2.84402059889376	0.00719767043993846	0.138626896377273
GO:0098531	ligand-modulated transcription factor activity	6/535	60/18639	0.1	3.48392523364486	0.00733723438032866	0.138626896377273
GO:0001223	transcription coactivator binding	5/535	44/18639	0.113636363636364	3.9590059473237	0.00825473423756772	0.149887054037734
GO:0034483	heparan sulfate sulfotransferase activity	3/535	15/18639	0.2	6.96785046728972	0.00827079464847857	0.149887054037734
GO:0001540	amyloid-beta binding	7/535	83/18639	0.0843373493975904	2.93825019704988	0.00979860986291719	0.173791806799536
GO:0016769	transferase activity, transferring nitrogenous groups	4/535	30/18639	0.133333333333333	4.64523364485981	0.0101769976954683	0.173791806799536
GO:0031624	ubiquitin conjugating enzyme binding	4/535	30/18639	0.133333333333333	4.64523364485981	0.0101769976954683	0.173791806799536
GO:0120013	lipid transfer activity	6/535	65/18639	0.0923076923076923	3.21593098490295	0.010743546211144	0.178794801686626
GO:0140359	ABC-type transporter activity	5/535	47/18639	0.106382978723404	3.70630344004772	0.0108726568593218	0.178794801686626
GO:0005164	tumor necrosis factor receptor binding	4/535	31/18639	0.129032258064516	4.49538739825143	0.0114252087247596	0.184465188137937
GO:0015278	intracellularly gated calcium channel activity	3/535	17/18639	0.176470588235294	6.14810335349093	0.011846565151091	0.1878526759673
GO:0008081	phosphoric diester hydrolase activity	7/535	87/18639	0.0804597701149425	2.80315823396713	0.0125155841680189	0.194346205088178
GO:0120015	sterol transfer activity	4/535	32/18639	0.125	4.35490654205607	0.0127677212271999	0.194346205088178
GO:0015280	ligand-gated sodium channel activity	3/535	18/18639	0.166666666666667	5.80654205607477	0.0139177500948005	0.194346205088178
GO:0017075	syntaxin-1 binding	3/535	18/18639	0.166666666666667	5.80654205607477	0.0139177500948005	0.194346205088178
GO:0034185	apolipoprotein binding	3/535	18/18639	0.166666666666667	5.80654205607477	0.0139177500948005	0.194346205088178
GO:0070064	proline-rich region binding	3/535	18/18639	0.166666666666667	5.80654205607477	0.0139177500948005	0.194346205088178
GO:0005319	lipid transporter activity	11/535	178/18639	0.0617977528089888	2.15298750393783	0.0139404232941598	0.194346205088178
GO:0032813	tumor necrosis factor receptor superfamily binding	5/535	50/18639	0.1	3.48392523364486	0.0140069337000488	0.194346205088178
GO:0140375	immune receptor activity	10/535	156/18639	0.0641025641025641	2.2332854061826	0.0147208926360982	0.201110040936233
GO:0050145	nucleoside monophosphate kinase activity	3/535	19/18639	0.157894736842105	5.50093457943925	0.0161812629299118	0.217711537602449
GO:0044325	transmembrane transporter binding	9/535	136/18639	0.0661764705882353	2.3055387575591	0.0166733764246537	0.220984451717798
GO:0051018	protein kinase A binding	5/535	53/18639	0.0943396226415094	3.28672191853289	0.0176972832782564	0.23110569928076
GO:0001614	purinergic nucleotide receptor activity	3/535	20/18639	0.15	5.22588785046729	0.0186387911508897	0.236446379171286
GO:0016502	nucleotide receptor activity	3/535	20/18639	0.15	5.22588785046729	0.0186387911508897	0.236446379171286
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/535	36/18639	0.111111111111111	3.87102803738318	0.0191242235273267	0.239187471722058
GO:0048029	monosaccharide binding	6/535	74/18639	0.0810810810810811	2.82480424349583	0.019456711721012	0.239966111225815
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/535	21/18639	0.142857142857143	4.97703604806409	0.0212913571039978	0.258720757360811
GO:0019902	phosphatase binding	11/535	190/18639	0.0578947368421053	2.01700934579439	0.021560063113401	0.258720757360811
GO:0000146	microfilament motor activity	4/535	38/18639	0.105263157894737	3.66728971962617	0.022919822522179	0.2713706986626
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/535	22/18639	0.136363636363636	4.75080713678844	0.0241393662869226	0.282049437668253
GO:0045309	protein phosphorylated amino acid binding	5/535	59/18639	0.0847457627118644	2.95247901156344	0.0268816287524758	0.305546784261836
GO:0005158	insulin receptor binding	3/535	23/18639	0.130434782608696	4.54425030475416	0.0271826531043751	0.305546784261836
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/535	23/18639	0.130434782608696	4.54425030475416	0.0271826531043751	0.305546784261836
GO:0042277	peptide binding	13/535	249/18639	0.0522088353413655	1.81891678864993	0.0281382334061409	0.312334390808164
GO:0042169	SH2 domain binding	4/535	41/18639	0.0975609756097561	3.3989514474584	0.029416001319545	0.312793713442519
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/535	24/18639	0.125	4.35490654205607	0.0304205241946729	0.312793713442519
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/535	24/18639	0.125	4.35490654205607	0.0304205241946729	0.312793713442519
GO:0004622	lysophospholipase activity	3/535	24/18639	0.125	4.35490654205607	0.0304205241946729	0.312793713442519
GO:0030552	cAMP binding	3/535	24/18639	0.125	4.35490654205607	0.0304205241946729	0.312793713442519
GO:0003779	actin binding	20/535	443/18639	0.0451467268623025	1.57287820932048	0.031585047954753	0.312793713442519
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/535	10/18639	0.2	6.96785046728972	0.0317667782736547	0.312793713442519
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/535	10/18639	0.2	6.96785046728972	0.0317667782736547	0.312793713442519
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/535	10/18639	0.2	6.96785046728972	0.0317667782736547	0.312793713442519
GO:0048487	beta-tubulin binding	4/535	42/18639	0.0952380952380952	3.31802403204272	0.0317992794785733	0.312793713442519
GO:0030165	PDZ domain binding	6/535	83/18639	0.072289156626506	2.5185001688999	0.0320543107244023	0.312793713442519
GO:0008483	transaminase activity	3/535	25/18639	0.12	4.18071028037383	0.0338517994375624	0.326743455440819
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	6/535	86/18639	0.0697674418604651	2.43064551184525	0.0372088490799647	0.334979570004525
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/535	26/18639	0.115384615384615	4.01991373112868	0.0374748507489834	0.334979570004525
GO:0034237	protein kinase A regulatory subunit binding	3/535	26/18639	0.115384615384615	4.01991373112868	0.0374748507489834	0.334979570004525
GO:0050750	low-density lipoprotein particle receptor binding	3/535	26/18639	0.115384615384615	4.01991373112868	0.0374748507489834	0.334979570004525
GO:0005536	D-glucose binding	2/535	11/18639	0.181818181818182	6.33440951571793	0.0381001537955597	0.334979570004525
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/535	11/18639	0.181818181818182	6.33440951571793	0.0381001537955597	0.334979570004525
GO:0019864	IgG binding	2/535	11/18639	0.181818181818182	6.33440951571793	0.0381001537955597	0.334979570004525
GO:0034056	estrogen response element binding	2/535	11/18639	0.181818181818182	6.33440951571793	0.0381001537955597	0.334979570004525
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/535	11/18639	0.181818181818182	6.33440951571793	0.0381001537955597	0.334979570004525
GO:0042605	peptide antigen binding	4/535	45/18639	0.0888888888888889	3.09682242990654	0.0396109025994952	0.339476140949232
GO:1902936	phosphatidylinositol bisphosphate binding	7/535	111/18639	0.0630630630630631	2.19706996716342	0.0408391536846507	0.339476140949232
GO:0061659	ubiquitin-like protein ligase activity	17/535	372/18639	0.0456989247311828	1.59211637021405	0.0409038531662562	0.339476140949232
GO:0005044	scavenger receptor activity	3/535	27/18639	0.111111111111111	3.87102803738318	0.0412876387640958	0.339476140949232
GO:0023026	MHC class II protein complex binding	3/535	27/18639	0.111111111111111	3.87102803738318	0.0412876387640958	0.339476140949232
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/535	27/18639	0.111111111111111	3.87102803738318	0.0412876387640958	0.339476140949232
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/535	27/18639	0.111111111111111	3.87102803738318	0.0412876387640958	0.339476140949232
GO:0022836	gated channel activity	15/535	318/18639	0.0471698113207547	1.64336095926644	0.0418974394465778	0.340334116335939
GO:0099094	ligand-gated monoatomic cation channel activity	8/535	136/18639	0.0588235294117647	2.04936778449698	0.0425152171118171	0.340334116335939
GO:0015276	ligand-gated monoatomic ion channel activity	10/535	186/18639	0.0537634408602151	1.87307808260476	0.0425417645419924	0.340334116335939
GO:0005178	integrin binding	9/535	161/18639	0.0559006211180124	1.94753584489464	0.0429358408510185	0.340419881033075
GO:0070679	inositol 1,4,5 trisphosphate binding	2/535	12/18639	0.166666666666667	5.80654205607477	0.0448675294169768	0.341446543903457
GO:0022834	ligand-gated channel activity	10/535	188/18639	0.0531914893617021	1.85315172002386	0.0451813823347595	0.341446543903457
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	16/535	349/18639	0.0458452722063037	1.59721500682859	0.0452278610772717	0.341446543903457
GO:0050698	proteoglycan sulfotransferase activity	3/535	28/18639	0.107142857142857	3.73277703604806	0.045287747505676	0.341446543903457
GO:0051959	dynein light intermediate chain binding	3/535	28/18639	0.107142857142857	3.73277703604806	0.045287747505676	0.341446543903457
GO:0001784	phosphotyrosine residue binding	4/535	47/18639	0.0851063829787234	2.96504275203818	0.0453724011042882	0.341446543903457
GO:0017124	SH3 domain binding	7/535	115/18639	0.0608695652173913	2.12065014221861	0.0478897289344174	0.349562755830031
GO:0035401	histone H3Y41 kinase activity	7/535	115/18639	0.0608695652173913	2.12065014221861	0.0478897289344174	0.349562755830031
GO:0140801	histone H2AXY142 kinase activity	7/535	115/18639	0.0608695652173913	2.12065014221861	0.0478897289344174	0.349562755830031
GO:0032266	phosphatidylinositol-3-phosphate binding	4/535	48/18639	0.0833333333333333	2.90327102803738	0.048419165503484	0.349562755830031
GO:0140693	molecular condensate scaffold activity	4/535	48/18639	0.0833333333333333	2.90327102803738	0.048419165503484	0.349562755830031
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/535	29/18639	0.103448275862069	3.60406058652917	0.0494724171309448	0.353201488675346
GO:0016755	aminoacyltransferase activity	21/535	496/18639	0.0423387096774194	1.47504899005125	0.0500180026228643	0.353201488675346
GO:0015399	primary active transmembrane transporter activity	9/535	166/18639	0.0542168674698795	1.88887512667492	0.0503832951425062	0.353201488675346
GO:0097110	scaffold protein binding	5/535	70/18639	0.0714285714285714	2.48851802403204	0.0505141768713614	0.353201488675346
GO:0008035	high-density lipoprotein particle binding	2/535	13/18639	0.153846153846154	5.35988497483825	0.0520388727452202	0.355465530751965
GO:0043560	insulin receptor substrate binding	2/535	13/18639	0.153846153846154	5.35988497483825	0.0520388727452202	0.355465530751965
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/535	13/18639	0.153846153846154	5.35988497483825	0.0520388727452202	0.355465530751965
GO:0140996	histone H3 kinase activity	16/535	357/18639	0.0448179271708683	1.56142307390246	0.0534115474932836	0.356781003457059
GO:0042562	hormone binding	6/535	94/18639	0.0638297872340425	2.22378206402863	0.0534339762274813	0.356781003457059
GO:0001965	G-protein alpha-subunit binding	3/535	30/18639	0.1	3.48392523364486	0.0538385748459977	0.356781003457059
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/535	30/18639	0.1	3.48392523364486	0.0538385748459977	0.356781003457059
GO:0019955	cytokine binding	8/535	144/18639	0.0555555555555556	1.93551401869159	0.0560223435779127	0.368502526645826
GO:0035173	histone kinase activity	16/535	360/18639	0.0444444444444444	1.54841121495327	0.0567305506168202	0.370013530723749
GO:0008194	UDP-glycosyltransferase activity	8/535	145/18639	0.0551724137931034	1.92216564614889	0.0578821483191265	0.370013530723749
GO:0016830	carbon-carbon lyase activity	4/535	51/18639	0.0784313725490196	2.7324903793293	0.0582192621461066	0.370013530723749
GO:0070273	phosphatidylinositol-4-phosphate binding	3/535	31/18639	0.0967741935483871	3.37154054868857	0.0583828640732732	0.370013530723749
GO:0070325	lipoprotein particle receptor binding	3/535	31/18639	0.0967741935483871	3.37154054868857	0.0583828640732732	0.370013530723749
GO:0008191	metalloendopeptidase inhibitor activity	2/535	14/18639	0.142857142857143	4.97703604806409	0.0595855122674506	0.370013530723749
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/535	14/18639	0.142857142857143	4.97703604806409	0.0595855122674506	0.370013530723749
GO:0061665	SUMO ligase activity	2/535	14/18639	0.142857142857143	4.97703604806409	0.0595855122674506	0.370013530723749
GO:0019787	ubiquitin-like protein transferase activity	20/535	479/18639	0.0417536534446764	1.45466606832771	0.0613771724022878	0.377883446962405
GO:0005080	protein kinase C binding	4/535	52/18639	0.0769230769230769	2.67994248741912	0.0617039412269692	0.377883446962405
GO:0071813	lipoprotein particle binding	3/535	32/18639	0.09375	3.26617990654206	0.0631016719539015	0.381185610170507
GO:0071814	protein-lipid complex binding	3/535	32/18639	0.09375	3.26617990654206	0.0631016719539015	0.381185610170507
GO:0008146	sulfotransferase activity	4/535	53/18639	0.0754716981132075	2.62937753482631	0.0652963214676805	0.390333357672442
GO:0004559	alpha-mannosidase activity	2/535	15/18639	0.133333333333333	4.64523364485981	0.0674800842088309	0.390333357672442
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/535	15/18639	0.133333333333333	4.64523364485981	0.0674800842088309	0.390333357672442
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/535	15/18639	0.133333333333333	4.64523364485981	0.0674800842088309	0.390333357672442
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/535	15/18639	0.133333333333333	4.64523364485981	0.0674800842088309	0.390333357672442
GO:0017081	chloride channel regulator activity	2/535	15/18639	0.133333333333333	4.64523364485981	0.0674800842088309	0.390333357672442
GO:0071889	14-3-3 protein binding	3/535	33/18639	0.0909090909090909	3.16720475785896	0.0679911552633287	0.390333357672442
GO:0005261	monoatomic cation channel activity	15/535	341/18639	0.0439882697947214	1.53251843122208	0.068132511755888	0.390333357672442
GO:0008376	acetylgalactosaminyltransferase activity	3/535	34/18639	0.0882352941176471	3.07405167674546	0.0730472648152968	0.404930574724755
GO:0015020	glucuronosyltransferase activity	3/535	34/18639	0.0882352941176471	3.07405167674546	0.0730472648152968	0.404930574724755
GO:0016831	carboxy-lyase activity	3/535	34/18639	0.0882352941176471	3.07405167674546	0.0730472648152968	0.404930574724755
GO:0019825	oxygen binding	3/535	34/18639	0.0882352941176471	3.07405167674546	0.0730472648152968	0.404930574724755
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/535	34/18639	0.0882352941176471	3.07405167674546	0.0730472648152968	0.404930574724755
GO:0042826	histone deacetylase binding	7/535	127/18639	0.0551181102362205	1.92027375082788	0.0734710470040812	0.404930574724755
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/535	16/18639	0.125	4.35490654205607	0.0756964813111591	0.404930574724755
GO:0015923	mannosidase activity	2/535	16/18639	0.125	4.35490654205607	0.0756964813111591	0.404930574724755
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/535	16/18639	0.125	4.35490654205607	0.0756964813111591	0.404930574724755
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/535	16/18639	0.125	4.35490654205607	0.0756964813111591	0.404930574724755
GO:0140328	floppase activity	2/535	16/18639	0.125	4.35490654205607	0.0756964813111591	0.404930574724755
GO:0005154	epidermal growth factor receptor binding	3/535	35/18639	0.0857142857142857	2.98622162883845	0.0782657684260741	0.41616767881649
GO:0051015	actin filament binding	10/535	209/18639	0.0478468899521531	1.66694987255735	0.0796904237005299	0.421220810988515
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	7/535	130/18639	0.0538461538461538	1.87595974119339	0.0809199983710702	0.425189103866925
GO:0004033	aldo-keto reductase (NADPH) activity	3/535	36/18639	0.0833333333333333	2.90327102803738	0.0836422725077783	0.432244540333303
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/535	36/18639	0.0833333333333333	2.90327102803738	0.0836422725077783	0.432244540333303
GO:0030169	low-density lipoprotein particle binding	2/535	17/18639	0.117647058823529	4.09873556899395	0.0842098034658349	0.432244540333303
GO:0045236	CXCR chemokine receptor binding	2/535	17/18639	0.117647058823529	4.09873556899395	0.0842098034658349	0.432244540333303
GO:0008013	beta-catenin binding	6/535	106/18639	0.0566037735849057	1.97203315111973	0.0847229369234092	0.432379126367743
GO:0061630	ubiquitin protein ligase activity	15/535	353/18639	0.0424929178470255	1.4804214873845	0.0854281118518944	0.43348664756847
GO:0141003	histone H2AX kinase activity	15/535	354/18639	0.0423728813559322	1.47623950578172	0.0869855394097111	0.438881585203543
GO:0070888	E-box binding	4/535	59/18639	0.0677966101694915	2.36198320925075	0.0890516077688246	0.441370634067973
GO:0023023	MHC protein complex binding	3/535	37/18639	0.0810810810810811	2.82480424349583	0.0891722423566915	0.441370634067973
GO:0030551	cyclic nucleotide binding	3/535	37/18639	0.0810810810810811	2.82480424349583	0.0891722423566915	0.441370634067973
GO:0015631	tubulin binding	16/535	385/18639	0.0415584415584416	1.4478650321641	0.0899860849874853	0.441370634067973
GO:0015079	potassium ion transmembrane transporter activity	8/535	160/18639	0.05	1.74196261682243	0.0904610984238413	0.441370634067973
GO:0099106	ion channel regulator activity	8/535	160/18639	0.05	1.74196261682243	0.0904610984238413	0.441370634067973
GO:0004970	glutamate-gated receptor activity	2/535	18/18639	0.111111111111111	3.87102803738318	0.0929963101372141	0.448808279357859
GO:0030228	lipoprotein particle receptor activity	2/535	18/18639	0.111111111111111	3.87102803738318	0.0929963101372141	0.448808279357859
GO:0004620	phospholipase activity	6/535	109/18639	0.055045871559633	1.91775700934579	0.0938436819148851	0.450449673191449
GO:0019838	growth factor binding	7/535	136/18639	0.0514705882352941	1.79319681143485	0.0970762845527907	0.461837803563764
GO:0004842	ubiquitin-protein transferase activity	18/535	449/18639	0.0400890868596882	1.39667381304248	0.0976414875524341	0.461837803563764
GO:0015026	coreceptor activity	4/535	61/18639	0.0655737704918033	2.2845411368163	0.0977764719256618	0.461837803563764
GO:0046873	metal ion transmembrane transporter activity	18/535	450/18639	0.04	1.39357009345794	0.0991515454523741	0.465616547272335
GO:0016922	nuclear receptor binding	7/535	137/18639	0.0510948905109489	1.78010778361416	0.099930352421519	0.465616547272335
GO:0015081	sodium ion transmembrane transporter activity	8/535	164/18639	0.0487804878048781	1.6994757237292	0.100633702480911	0.465616547272335
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/535	39/18639	0.0769230769230769	2.67994248741912	0.100673848058883	0.465616547272335
GO:0022821	solute:potassium antiporter activity	2/535	19/18639	0.105263157894737	3.66728971962617	0.102033374514544	0.467039363757293
GO:0042800	histone H3K4 methyltransferase activity	2/535	19/18639	0.105263157894737	3.66728971962617	0.102033374514544	0.467039363757293
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	19/535	484/18639	0.0392561983471074	1.36765659998455	0.105364888470999	0.479224875887324
GO:0030295	protein kinase activator activity	7/535	139/18639	0.0503597122302158	1.75449472197943	0.105774859993148	0.479224875887324
GO:0015144	carbohydrate transmembrane transporter activity	3/535	40/18639	0.075	2.61294392523364	0.106635874493078	0.479356306654663
GO:0005507	copper ion binding	4/535	63/18639	0.0634920634920635	2.21201602136182	0.106883500808134	0.479356306654663
GO:0030246	carbohydrate binding	12/535	280/18639	0.0428571428571429	1.49311081441923	0.109794856153484	0.485684412966985
GO:0015095	magnesium ion transmembrane transporter activity	2/535	20/18639	0.1	3.48392523364486	0.111299439332728	0.485684412966985
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/535	20/18639	0.1	3.48392523364486	0.111299439332728	0.485684412966985
GO:0031418	L-ascorbic acid binding	2/535	20/18639	0.1	3.48392523364486	0.111299439332728	0.485684412966985
GO:0016247	channel regulator activity	8/535	168/18639	0.0476190476190476	1.65901201602136	0.111421530573729	0.485684412966985
GO:0140297	DNA-binding transcription factor binding	19/535	488/18639	0.0389344262295082	1.35644629998468	0.111576148924848	0.485684412966985
GO:0001530	lipopolysaccharide binding	3/535	41/18639	0.0731707317073171	2.5492135855938	0.112732180269935	0.485952311066518
GO:0140318	protein transporter activity	3/535	41/18639	0.0731707317073171	2.5492135855938	0.112732180269935	0.485952311066518
GO:0016758	hexosyltransferase activity	9/535	197/18639	0.0456852791878173	1.59164096968547	0.114964900672724	0.49318276230618
GO:0001216	DNA-binding transcription activator activity	19/535	491/18639	0.0386965376782077	1.34815844071797	0.116379677516215	0.494927716324117
GO:0141108	transporter regulator activity	8/535	170/18639	0.0470588235294118	1.63949422759758	0.117042693522493	0.494927716324117
GO:0061134	peptidase regulator activity	10/535	226/18639	0.0442477876106195	1.54155983789596	0.117043716698271	0.494927716324117
GO:0035198	miRNA binding	3/535	42/18639	0.0714285714285714	2.48851802403204	0.118957788023117	0.496515227694934
GO:0004674	protein serine/threonine kinase activity	17/535	433/18639	0.0392609699769053	1.36782283999914	0.120367386090094	0.496515227694934
GO:0005123	death receptor binding	2/535	21/18639	0.0952380952380952	3.31802403204272	0.120773974304173	0.496515227694934
GO:0005248	voltage-gated sodium channel activity	2/535	21/18639	0.0952380952380952	3.31802403204272	0.120773974304173	0.496515227694934
GO:0010314	phosphatidylinositol-5-phosphate binding	2/535	21/18639	0.0952380952380952	3.31802403204272	0.120773974304173	0.496515227694934
GO:0061891	calcium ion sensor activity	2/535	21/18639	0.0952380952380952	3.31802403204272	0.120773974304173	0.496515227694934
GO:0008200	ion channel inhibitor activity	3/535	43/18639	0.0697674418604651	2.43064551184525	0.125307676944141	0.508096881855697
GO:0008375	acetylglucosaminyltransferase activity	3/535	43/18639	0.0697674418604651	2.43064551184525	0.125307676944141	0.508096881855697
GO:0048156	tau protein binding	3/535	43/18639	0.0697674418604651	2.43064551184525	0.125307676944141	0.508096881855697
GO:0051219	phosphoprotein binding	5/535	93/18639	0.0537634408602151	1.87307808260476	0.129208518933214	0.520079086467393
GO:0050321	tau-protein kinase activity	2/535	22/18639	0.0909090909090909	3.16720475785896	0.130437435105898	0.520079086467393
GO:0140784	metal ion sensor activity	2/535	22/18639	0.0909090909090909	3.16720475785896	0.130437435105898	0.520079086467393
GO:0005548	phospholipid transporter activity	4/535	68/18639	0.0588235294117647	2.04936778449698	0.131225668185924	0.520079086467393
GO:0016248	channel inhibitor activity	3/535	44/18639	0.0681818181818182	2.37540356839422	0.131776795557616	0.520079086467393
GO:0019205	nucleobase-containing compound kinase activity	3/535	44/18639	0.0681818181818182	2.37540356839422	0.131776795557616	0.520079086467393
GO:0019209	kinase activator activity	7/535	148/18639	0.0472972972972973	1.64780247537257	0.13426516284562	0.527555153127924
GO:0044389	ubiquitin-like protein ligase binding	13/535	322/18639	0.0403726708074534	1.40655366575724	0.13749902199518	0.536522905589239
GO:0140303	intramembrane lipid transporter activity	3/535	45/18639	0.0666666666666667	2.32261682242991	0.138360073626054	0.536522905589239
GO:0141110	transporter inhibitor activity	3/535	45/18639	0.0666666666666667	2.32261682242991	0.138360073626054	0.536522905589239
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/535	122/18639	0.0491803278688525	1.71340585261223	0.139051291083264	0.536858897747558
GO:0140103	catalytic activity, acting on a glycoprotein	2/535	23/18639	0.0869565217391304	3.02950020316944	0.140271223867948	0.539224444998864
GO:0016782	transferase activity, transferring sulphur-containing groups	4/535	70/18639	0.0571428571428571	1.99081441922563	0.141550064452564	0.541795074283952
GO:0005267	potassium channel activity	6/535	124/18639	0.0483870967741935	1.68577027434429	0.146777072975101	0.559390733055322
GO:0016757	glycosyltransferase activity	11/535	267/18639	0.0411985018726592	1.43532500262522	0.147558397728746	0.55950926788779
GO:0005216	monoatomic ion channel activity	17/535	448/18639	0.0379464285714286	1.32202520026702	0.148660722843045	0.55950926788779
GO:0015149	hexose transmembrane transporter activity	2/535	24/18639	0.0833333333333333	2.90327102803738	0.150257651110973	0.55950926788779
GO:0015295	solute:proton symporter activity	2/535	24/18639	0.0833333333333333	2.90327102803738	0.150257651110973	0.55950926788779
GO:0055056	D-glucose transmembrane transporter activity	2/535	24/18639	0.0833333333333333	2.90327102803738	0.150257651110973	0.55950926788779
GO:0008170	N-methyltransferase activity	5/535	98/18639	0.0510204081632653	1.7775128743086	0.151103177259536	0.55950926788779
GO:0043495	protein-membrane adaptor activity	3/535	47/18639	0.0638297872340425	2.22378206402863	0.151848799055132	0.55950926788779
GO:0140938	histone H3 methyltransferase activity	3/535	47/18639	0.0638297872340425	2.22378206402863	0.151848799055132	0.55950926788779
GO:0043539	protein serine/threonine kinase activator activity	4/535	73/18639	0.0547945205479452	1.90900012802458	0.157612315927613	0.578346018775703
GO:0038187	pattern recognition receptor activity	3/535	48/18639	0.0625	2.17745327102804	0.158744107958575	0.580101925379485
GO:0017025	TBP-class protein binding	2/535	25/18639	0.08	2.78714018691589	0.160379899082574	0.581524409198879
GO:0061135	endopeptidase regulator activity	8/535	184/18639	0.0434782608695652	1.51475010158472	0.160443108393835	0.581524409198879
GO:0031625	ubiquitin protein ligase binding	12/535	302/18639	0.0397350993377483	1.38434115244167	0.161265514270864	0.582036891675008
GO:0042578	phosphoric ester hydrolase activity	14/535	363/18639	0.0385674931129477	1.34366262454623	0.162787346700247	0.582036891675008
GO:0001222	transcription corepressor binding	3/535	49/18639	0.0612244897959184	2.13301544917032	0.165733317799931	0.582036891675008
GO:0045296	cadherin binding	13/535	334/18639	0.0389221556886228	1.35601880351447	0.166021812096244	0.582036891675008
GO:0035591	signaling adaptor activity	6/535	129/18639	0.0465116279069767	1.62043034123017	0.166910808328925	0.582036891675008
GO:0015171	amino acid transmembrane transporter activity	5/535	102/18639	0.0490196078431373	1.70780648708081	0.169658146111647	0.582036891675008
GO:0004435	phosphatidylinositol phospholipase C activity	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0005112	Notch binding	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0008066	glutamate receptor activity	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0015145	monosaccharide transmembrane transporter activity	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0019865	immunoglobulin binding	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0030247	polysaccharide binding	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0030507	spectrin binding	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0043548	phosphatidylinositol 3-kinase binding	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0052742	phosphatidylinositol kinase activity	2/535	26/18639	0.0769230769230769	2.67994248741912	0.170621986443706	0.582036891675008
GO:0016298	lipase activity	6/535	130/18639	0.0461538461538462	1.60796549245147	0.171071653972046	0.582036891675008
GO:0033218	amide binding	10/535	247/18639	0.0404858299595142	1.41049604601006	0.174449800053764	0.591264971174589
GO:0001217	DNA-binding transcription repressor activity	11/535	278/18639	0.039568345323741	1.37853156726955	0.177628277525591	0.5997487089077
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	6/535	132/18639	0.0454545454545455	1.58360237892948	0.179520753120811	0.600629053404685
GO:0005021	vascular endothelial growth factor receptor activity	3/535	51/18639	0.0588235294117647	2.04936778449698	0.179973425219555	0.600629053404685
GO:0004683	calcium/calmodulin-dependent protein kinase activity	2/535	27/18639	0.0740740740740741	2.58068535825545	0.180968734258075	0.600629053404685
GO:0035255	ionotropic glutamate receptor binding	2/535	27/18639	0.0740740740740741	2.58068535825545	0.180968734258075	0.600629053404685
GO:0004866	endopeptidase inhibitor activity	7/535	161/18639	0.0434782608695652	1.51475010158472	0.181270930532045	0.600629053404685
GO:0019199	transmembrane receptor protein kinase activity	4/535	78/18639	0.0512820512820513	1.78662832494608	0.185766017102567	0.613235030435238
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/535	52/18639	0.0576923076923077	2.00995686556434	0.187214414035428	0.615727406160963
GO:0019789	SUMO transferase activity	2/535	28/18639	0.0714285714285714	2.48851802403204	0.191405733239029	0.624883423221535
GO:0051119	sugar transmembrane transporter activity	2/535	28/18639	0.0714285714285714	2.48851802403204	0.191405733239029	0.624883423221535
GO:0005544	calcium-dependent phospholipid binding	3/535	53/18639	0.0566037735849057	1.97203315111973	0.194529499589493	0.628153438674435
GO:0017046	peptide hormone binding	3/535	53/18639	0.0566037735849057	1.97203315111973	0.194529499589493	0.628153438674435
GO:0140296	general transcription initiation factor binding	3/535	53/18639	0.0566037735849057	1.97203315111973	0.194529499589493	0.628153438674435
GO:0019887	protein kinase regulator activity	10/535	255/18639	0.0392156862745098	1.36624518966465	0.199277855721759	0.641154840148268
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3/535	54/18639	0.0555555555555556	1.93551401869159	0.201913855296227	0.642667918431822
GO:0051287	NAD binding	3/535	54/18639	0.0555555555555556	1.93551401869159	0.201913855296227	0.642667918431822
GO:0004629	phospholipase C activity	2/535	29/18639	0.0689655172413793	2.40270705768611	0.201919312209998	0.642667918431822
GO:0001618	virus receptor activity	4/535	81/18639	0.0493827160493827	1.72045690550363	0.203385143875762	0.645021456291702
GO:0140272	exogenous protein binding	4/535	82/18639	0.0487804878048781	1.6994757237292	0.209365083644997	0.661623467177071
GO:0001968	fibronectin binding	2/535	30/18639	0.0666666666666667	2.32261682242991	0.212496507735998	0.666584553430137
GO:0070566	adenylyltransferase activity	2/535	30/18639	0.0666666666666667	2.32261682242991	0.212496507735998	0.666584553430137
GO:0030414	peptidase inhibitor activity	7/535	169/18639	0.0414201183431953	1.44304595476414	0.213186951772701	0.666584553430137
GO:0005200	structural constituent of cytoskeleton	5/535	112/18639	0.0446428571428571	1.55532376502003	0.219505783309174	0.666606661143329
GO:0017147	Wnt-protein binding	2/535	31/18639	0.0645161290322581	2.24769369912572	0.223125034885151	0.666606661143329
GO:0004601	peroxidase activity	3/535	57/18639	0.0526315789473684	1.83364485981308	0.224435224686171	0.666606661143329
GO:0016504	peptidase activator activity	3/535	57/18639	0.0526315789473684	1.83364485981308	0.224435224686171	0.666606661143329
GO:0061980	regulatory RNA binding	3/535	58/18639	0.0517241379310345	1.80203029326458	0.232049689999751	0.666606661143329
GO:0019903	protein phosphatase binding	6/535	144/18639	0.0416666666666667	1.45163551401869	0.233402906100673	0.666606661143329
GO:0051059	NF-kappaB binding	2/535	32/18639	0.0625	2.17745327102804	0.233793259080568	0.666606661143329
GO:0015459	potassium channel regulator activity	3/535	59/18639	0.0508474576271186	1.77148740693806	0.239710301547836	0.666606661143329
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/535	59/18639	0.0508474576271186	1.77148740693806	0.239710301547836	0.666606661143329
GO:0070063	RNA polymerase binding	3/535	59/18639	0.0508474576271186	1.77148740693806	0.239710301547836	0.666606661143329
GO:0022804	active transmembrane transporter activity	16/535	457/18639	0.0350109409190372	1.21975500521483	0.242212761411023	0.666606661143329
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	10/535	268/18639	0.0373134328358209	1.29997210210629	0.24258178465431	0.666606661143329
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/535	60/18639	0.05	1.74196261682243	0.247412664318568	0.666606661143329
GO:0000182	rDNA binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0004090	carbonyl reductase (NADPH) activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0005131	growth hormone receptor binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0005381	iron ion transmembrane transporter activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0008239	dipeptidyl-peptidase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0015203	polyamine transmembrane transporter activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0016868	intramolecular phosphotransferase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0031996	thioesterase binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0032395	MHC class II receptor activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0043121	neurotrophin binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0043422	protein kinase B binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0050815	phosphoserine residue binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0051378	serotonin binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0070739	protein-glutamic acid ligase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0070740	tubulin-glutamic acid ligase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0099122	RNA polymerase II C-terminal domain binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0140135	mechanosensitive monoatomic cation channel activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0140999	histone H3K4 trimethyltransferase activity	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:1905394	retromer complex binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:1990763	arrestin family protein binding	1/535	10/18639	0.1	3.48392523364486	0.252711446059363	0.666606661143329
GO:0003712	transcription coregulator activity	17/535	495/18639	0.0343434343434343	1.19649957519116	0.25779309296264	0.666606661143329
GO:0032182	ubiquitin-like protein binding	5/535	120/18639	0.0416666666666667	1.45163551401869	0.262199504068963	0.666606661143329
GO:0015179	L-amino acid transmembrane transporter activity	3/535	62/18639	0.0483870967741935	1.68577027434429	0.262925486345648	0.666606661143329
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4/535	91/18639	0.043956043956044	1.53139570709664	0.265127070174937	0.666606661143329
GO:0043015	gamma-tubulin binding	2/535	35/18639	0.0571428571428571	1.99081441922563	0.265928961551827	0.666606661143329
GO:0005126	cytokine receptor binding	10/535	275/18639	0.0363636363636364	1.26688190314359	0.267197217992282	0.666606661143329
GO:0008017	microtubule binding	10/535	276/18639	0.036231884057971	1.2622917513206	0.270777736441428	0.666606661143329
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0001851	complement component C3b binding	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0002162	dystroglycan binding	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0005225	volume-sensitive anion channel activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0008526	phosphatidylinositol transfer activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0015173	aromatic amino acid transmembrane transporter activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0035252	UDP-xylosyltransferase activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0042285	xylosyltransferase activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0042608	T cell receptor binding	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0050998	nitric-oxide synthase binding	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0097493	structural molecule activity conferring elasticity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0140031	phosphorylation-dependent protein binding	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0140537	transcription regulator activator activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0180030	inositol phosphate kinase activity	1/535	11/18639	0.0909090909090909	3.16720475785896	0.274172575285743	0.666606661143329
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/535	36/18639	0.0555555555555556	1.93551401869159	0.276651707966184	0.666606661143329
GO:0003774	cytoskeletal motor activity	6/535	153/18639	0.0392156862745098	1.36624518966465	0.276705103970147	0.666606661143329
GO:0035403	histone H3T6 kinase activity	9/535	247/18639	0.0364372469635627	1.26944644140906	0.280064825659722	0.666606661143329
GO:0042393	histone binding	9/535	247/18639	0.0364372469635627	1.26944644140906	0.280064825659722	0.666606661143329
GO:0019213	deacetylase activity	2/535	37/18639	0.0540540540540541	1.88320282899722	0.287364820286726	0.666606661143329
GO:0004032	aldose reductase (NADPH) activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0004300	enoyl-CoA hydratase activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0004875	complement receptor activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0005025	transforming growth factor beta receptor activity, type I	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0005026	transforming growth factor beta receptor activity, type II	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0005049	nuclear export signal receptor activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0005078	MAP-kinase scaffold activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0005095	GTPase inhibitor activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0008179	adenylate cyclase binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0008504	monoamine transmembrane transporter activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0008603	cAMP-dependent protein kinase regulator activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0015368	calcium:monoatomic cation antiporter activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0016208	AMP binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0016361	activin receptor activity, type I	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0016362	activin receptor activity, type II	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0016840	carbon-nitrogen lyase activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0017002	activin receptor activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0017166	vinculin binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0031543	peptidyl-proline dioxygenase activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0035251	UDP-glucosyltransferase activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0045295	gamma-catenin binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0070008	serine-type exopeptidase activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0097371	MDM2/MDM4 family protein binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0097677	STAT family protein binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:1990459	transferrin receptor binding	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:1990817	poly(A) RNA polymerase activity	1/535	12/18639	0.0833333333333333	2.90327102803738	0.295018488546541	0.666606661143329
GO:0004896	cytokine receptor activity	4/535	96/18639	0.0416666666666667	1.45163551401869	0.297210545260998	0.669855239065396
GO:0043531	ADP binding	2/535	38/18639	0.0526315789473684	1.83364485981308	0.298060031347119	0.670069133762637
GO:0042054	histone methyltransferase activity	3/535	67/18639	0.0447761194029851	1.55996652252755	0.302147277701321	0.673514633213089
GO:0050840	extracellular matrix binding	3/535	67/18639	0.0447761194029851	1.55996652252755	0.302147277701321	0.673514633213089
GO:0030145	manganese ion binding	3/535	68/18639	0.0441176470588235	1.53702583837273	0.310035967371263	0.673514633213089
GO:0019207	kinase regulator activity	10/535	287/18639	0.0348432055749129	1.21391123123514	0.311059946486566	0.673514633213089
GO:0004993	G protein-coupled serotonin receptor activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0005542	folic acid binding	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0008253	5'-nucleotidase activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0031994	insulin-like growth factor I binding	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0032396	inhibitory MHC class I receptor activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0035325	Toll-like receptor binding	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0046974	histone H3K9 methyltransferase activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0046975	histone H3K36 methyltransferase activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0051011	microtubule minus-end binding	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0070123	transforming growth factor beta receptor activity, type III	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0089720	caspase binding	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0140333	glycerophospholipid flippase activity	1/535	13/18639	0.0769230769230769	2.67994248741912	0.315266789863318	0.673514633213089
GO:0016798	hydrolase activity, acting on glycosyl bonds	5/535	130/18639	0.0384615384615385	1.33997124370956	0.317872568783116	0.673514633213089
GO:0016279	protein-lysine N-methyltransferase activity	3/535	69/18639	0.0434782608695652	1.51475010158472	0.317930874354791	0.673514633213089
GO:0071949	FAD binding	2/535	40/18639	0.05	1.74196261682243	0.319366064256264	0.673514633213089
GO:0043130	ubiquitin binding	4/535	100/18639	0.04	1.39357009345794	0.32320474219426	0.673514633213089
GO:0016278	lysine N-methyltransferase activity	3/535	70/18639	0.0428571428571429	1.49311081441923	0.325828522559367	0.673514633213089
GO:0001727	lipid kinase activity	2/535	41/18639	0.0487804878048781	1.6994757237292	0.329962673691461	0.673514633213089
GO:0008227	G protein-coupled amine receptor activity	2/535	41/18639	0.0487804878048781	1.6994757237292	0.329962673691461	0.673514633213089
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/535	41/18639	0.0487804878048781	1.6994757237292	0.329962673691461	0.673514633213089
GO:0140828	metal cation:monoatomic cation antiporter activity	2/535	41/18639	0.0487804878048781	1.6994757237292	0.329962673691461	0.673514633213089
GO:0140299	molecular sensor activity	3/535	71/18639	0.0422535211267606	1.47208108463867	0.333725532793548	0.673514633213089
GO:0004065	arylsulfatase activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0008174	mRNA methyltransferase activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0008331	high voltage-gated calcium channel activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0008474	palmitoyl-(protein) hydrolase activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0008559	ABC-type xenobiotic transporter activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0015386	potassium:proton antiporter activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0016530	metallochaperone activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0031404	chloride ion binding	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0034236	protein kinase A catalytic subunit binding	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0042043	neurexin family protein binding	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0042813	Wnt receptor activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0043176	amine binding	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0046030	inositol trisphosphate phosphatase activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0071933	Arp2/3 complex binding	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0098599	palmitoyl hydrolase activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0098821	BMP receptor activity	1/535	14/18639	0.0714285714285714	2.48851802403204	0.334934580447614	0.673514633213089
GO:0008307	structural constituent of muscle	2/535	42/18639	0.0476190476190476	1.65901201602136	0.340512917974877	0.673514633213089
GO:0043175	RNA polymerase core enzyme binding	2/535	42/18639	0.0476190476190476	1.65901201602136	0.340512917974877	0.673514633213089
GO:0051879	Hsp90 protein binding	2/535	42/18639	0.0476190476190476	1.65901201602136	0.340512917974877	0.673514633213089
GO:0106310	protein serine kinase activity	12/535	361/18639	0.0332409972299169	1.15809149040826	0.343150700052413	0.673514633213089
GO:0001664	G protein-coupled receptor binding	10/535	297/18639	0.0336700336700337	1.17303879920702	0.348803834688249	0.673514633213089
GO:0004521	RNA endonuclease activity	3/535	73/18639	0.0410958904109589	1.43175009601844	0.349504607433881	0.673514633213089
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/535	73/18639	0.0410958904109589	1.43175009601844	0.349504607433881	0.673514633213089
GO:0005245	voltage-gated calcium channel activity	2/535	43/18639	0.0465116279069767	1.62043034123017	0.351010734610523	0.673514633213089
GO:0016829	lyase activity	7/535	200/18639	0.035	1.2193738317757	0.351246117119849	0.673514633213089
GO:0002020	protease binding	5/535	136/18639	0.0367647058823529	1.28085486531061	0.351963851670606	0.673514633213089
GO:0016779	nucleotidyltransferase activity	5/535	136/18639	0.0367647058823529	1.28085486531061	0.351963851670606	0.673514633213089
GO:0005041	low-density lipoprotein particle receptor activity	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0008252	nucleotidase activity	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0010181	FMN binding	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0015929	hexosaminidase activity	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0030553	cGMP binding	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0033130	acetylcholine receptor binding	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0051371	muscle alpha-actinin binding	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0120283	protein serine/threonine kinase binding	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0140776	protein-containing complex destabilizing activity	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0141050	histone H3K deacetylase activity	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0141051	histone H4K deacetylase activity	1/535	15/18639	0.0666666666666667	2.32261682242991	0.354038473036099	0.673514633213089
GO:0001046	core promoter sequence-specific DNA binding	2/535	44/18639	0.0454545454545455	1.58360237892948	0.361450445993995	0.673514633213089
GO:0070851	growth factor receptor binding	5/535	139/18639	0.0359712230215827	1.25321051569959	0.369088050529336	0.673514633213089
GO:0004708	MAP kinase kinase activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0005024	transforming growth factor beta receptor activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0005159	insulin-like growth factor receptor binding	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0005521	lamin binding	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0008142	oxysterol binding	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0015385	sodium:proton antiporter activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0016722	oxidoreductase activity, acting on metal ions	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0022858	alanine transmembrane transporter activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0034450	ubiquitin-ubiquitin ligase activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0140327	flippase activity	1/535	16/18639	0.0625	2.17745327102804	0.372594605817762	0.673514633213089
GO:0004180	carboxypeptidase activity	2/535	46/18639	0.0434782608695652	1.51475010158472	0.382134665526598	0.673514633213089
GO:0030276	clathrin binding	2/535	46/18639	0.0434782608695652	1.51475010158472	0.382134665526598	0.673514633213089
GO:0022832	voltage-gated channel activity	6/535	175/18639	0.0342857142857143	1.19448865153538	0.388128338314791	0.673514633213089
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0004659	prenyltransferase activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0005092	GDP-dissociation inhibitor activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0008484	sulfuric ester hydrolase activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0008569	minus-end-directed microtubule motor activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0009881	photoreceptor activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0016805	dipeptidase activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0031489	myosin V binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0032183	SUMO binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0036041	long-chain fatty acid binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0045125	bioactive lipid receptor activity	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0046965	nuclear retinoid X receptor binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0048038	quinone binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0070402	NADPH binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0070403	NAD+ binding	1/535	17/18639	0.0588235294117647	2.04936778449698	0.390618655964758	0.673514633213089
GO:0022843	voltage-gated monoatomic cation channel activity	5/535	143/18639	0.034965034965035	1.2181556760996	0.391925400349745	0.673514633213089
GO:0061749	forked DNA-dependent helicase activity	2/535	47/18639	0.0425531914893617	1.48252137601909	0.39236959292533	0.673514633213089
GO:0099095	ligand-gated monoatomic anion channel activity	2/535	47/18639	0.0425531914893617	1.48252137601909	0.39236959292533	0.673514633213089
GO:1990518	single-stranded 3'-5' DNA helicase activity	2/535	47/18639	0.0425531914893617	1.48252137601909	0.39236959292533	0.673514633213089
GO:0046332	SMAD binding	3/535	79/18639	0.0379746835443038	1.32300958239678	0.396505046990321	0.673514633213089
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	8/535	243/18639	0.0329218106995885	1.14697127033576	0.397423914708841	0.673514633213089
GO:0009378	four-way junction helicase activity	2/535	48/18639	0.0416666666666667	1.45163551401869	0.402527222706493	0.673514633213089
GO:0036121	double-stranded DNA helicase activity	2/535	48/18639	0.0416666666666667	1.45163551401869	0.402527222706493	0.673514633213089
GO:0043138	3'-5' DNA helicase activity	2/535	48/18639	0.0416666666666667	1.45163551401869	0.402527222706493	0.673514633213089
GO:0048306	calcium-dependent protein binding	3/535	80/18639	0.0375	1.30647196261682	0.404260163241807	0.673514633213089
GO:0004676	3-phosphoinositide-dependent protein kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0004711	ribosomal protein S6 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0035175	histone H3S10 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0035979	histone H2AXS139 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0044022	histone H3S28 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0044023	histone H4S1 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0044024	histone H2AS1 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0044025	histone H2BS14 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0072354	histone H3T3 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0072371	histone H2AS121 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0072518	Rho-dependent protein serine/threonine kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0140823	histone H2BS36 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0140855	histone H3S57 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0140995	histone H2A kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0140997	histone H4 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0140998	histone H2B kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:1990244	histone H2AT120 kinase activity	8/535	245/18639	0.0326530612244898	1.13760823955751	0.406160157549468	0.673514633213089
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0004706	JUN kinase kinase kinase activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0008525	phosphatidylcholine transporter activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0016854	racemase and epimerase activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0031690	adrenergic receptor binding	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0032393	MHC class I receptor activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0035615	clathrin adaptor activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0050811	GABA receptor binding	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0098641	cadherin binding involved in cell-cell adhesion	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:1901611	phosphatidylglycerol binding	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:1990381	ubiquitin-specific protease binding	1/535	18/18639	0.0555555555555556	1.93551401869159	0.408125852778143	0.673514633213089
GO:0004677	DNA-dependent protein kinase activity	8/535	246/18639	0.032520325203252	1.13298381581947	0.41052801142042	0.673514633213089
GO:0140857	histone H3T45 kinase activity	8/535	246/18639	0.032520325203252	1.13298381581947	0.41052801142042	0.673514633213089
GO:0015101	organic cation transmembrane transporter activity	3/535	81/18639	0.037037037037037	1.29034267912773	0.411986125525117	0.673514633213089
GO:0030971	receptor tyrosine kinase binding	3/535	81/18639	0.037037037037037	1.29034267912773	0.411986125525117	0.673514633213089
GO:0016763	pentosyltransferase activity	2/535	49/18639	0.0408163265306122	1.42201029944688	0.412603559085496	0.673514633213089
GO:0035254	glutamate receptor binding	2/535	49/18639	0.0408163265306122	1.42201029944688	0.412603559085496	0.673514633213089
GO:0035402	histone H3T11 kinase activity	8/535	247/18639	0.0323886639676113	1.12839683680805	0.414894979981448	0.676012371052341
GO:0004679	AMP-activated protein kinase activity	8/535	248/18639	0.032258064516129	1.12384684956286	0.419260538751488	0.67655254395698
GO:0016887	ATP hydrolysis activity	13/535	417/18639	0.0311750599520384	1.08611578027298	0.420376069130396	0.67655254395698
GO:0140104	molecular carrier activity	8/535	249/18639	0.0321285140562249	1.11933340839995	0.423624167989961	0.67655254395698
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0005229	intracellularly calcium-gated chloride channel activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0005520	insulin-like growth factor binding	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0008381	mechanosensitive monoatomic ion channel activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0046527	glucosyltransferase activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0046624	sphingolipid transporter activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0099589	serotonin receptor activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0141147	intracellularly calcium-gated channel activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:1990380	K48-linked deubiquitinase activity	1/535	19/18639	0.0526315789473684	1.83364485981308	0.425130990459454	0.67655254395698
GO:0019842	vitamin binding	5/535	150/18639	0.0333333333333333	1.16130841121495	0.431694196814033	0.685768241092775
GO:0051117	ATPase binding	3/535	84/18639	0.0357142857142857	1.24425901201602	0.434966150623549	0.689732038845914
GO:0015078	proton transmembrane transporter activity	6/535	185/18639	0.0324324324324324	1.12992169739833	0.439309517426034	0.691497406232216
GO:0022853	active monoatomic ion transmembrane transporter activity	4/535	118/18639	0.0338983050847458	1.18099160462538	0.440276468359746	0.691497406232216
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/535	20/18639	0.05	1.74196261682243	0.441648440518755	0.691497406232216
GO:0016004	phospholipase activator activity	1/535	20/18639	0.05	1.74196261682243	0.441648440518755	0.691497406232216
GO:0016505	peptidase activator activity involved in apoptotic process	1/535	20/18639	0.05	1.74196261682243	0.441648440518755	0.691497406232216
GO:0030742	GTP-dependent protein binding	1/535	20/18639	0.05	1.74196261682243	0.441648440518755	0.691497406232216
GO:0052745	inositol phosphate phosphatase activity	1/535	20/18639	0.05	1.74196261682243	0.441648440518755	0.691497406232216
GO:0030159	signaling receptor complex adaptor activity	2/535	52/18639	0.0384615384615385	1.33997124370956	0.44230915173412	0.691497406232216
GO:0016209	antioxidant activity	3/535	86/18639	0.0348837209302326	1.21532275592263	0.45009988711896	0.701617431449143
GO:0005246	calcium channel regulator activity	2/535	53/18639	0.0377358490566038	1.31468876741315	0.452026000837831	0.701617431449143
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/535	53/18639	0.0377358490566038	1.31468876741315	0.452026000837831	0.701617431449143
GO:0003713	transcription coactivator activity	8/535	256/18639	0.03125	1.08872663551402	0.454072939913108	0.701617431449143
GO:0001846	opsonin binding	1/535	21/18639	0.0476190476190476	1.65901201602136	0.457692163829485	0.701617431449143
GO:0008373	sialyltransferase activity	1/535	21/18639	0.0476190476190476	1.65901201602136	0.457692163829485	0.701617431449143
GO:0036122	BMP binding	1/535	21/18639	0.0476190476190476	1.65901201602136	0.457692163829485	0.701617431449143
GO:0051428	peptide hormone receptor binding	1/535	21/18639	0.0476190476190476	1.65901201602136	0.457692163829485	0.701617431449143
GO:0140312	cargo adaptor activity	1/535	21/18639	0.0476190476190476	1.65901201602136	0.457692163829485	0.701617431449143
GO:0003925	G protein activity	2/535	54/18639	0.037037037037037	1.29034267912773	0.461645698743277	0.701617431449143
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/535	54/18639	0.037037037037037	1.29034267912773	0.461645698743277	0.701617431449143
GO:0050661	NADP binding	2/535	54/18639	0.037037037037037	1.29034267912773	0.461645698743277	0.701617431449143
GO:0098632	cell-cell adhesion mediator activity	2/535	55/18639	0.0363636363636364	1.26688190314359	0.471165811306982	0.701617431449143
GO:0004407	histone deacetylase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0008970	phospholipase A1 activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0016881	acid-amino acid ligase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0032931	histone H3K56 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0033558	protein lysine deacetylase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0043992	histone H3K9 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0043993	histone H3K18 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0043994	histone H3K23 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0043999	histone H2AK5 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0044012	histone H2AK9 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0044014	histone H2BK5 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0044015	histone H2BK12 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0044016	histone H3K4 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0044017	histone H3K27 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0044018	histone H3K36 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0046972	histone H4K16 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0061133	endopeptidase activator activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0140908	histone H3K122 acetyltransferase activity	1/535	22/18639	0.0454545454545455	1.58360237892948	0.473275722340131	0.701617431449143
GO:0019001	guanyl nucleotide binding	12/535	400/18639	0.03	1.04517757009346	0.479407096811145	0.707725873425963
GO:0032561	guanyl ribonucleotide binding	12/535	400/18639	0.03	1.04517757009346	0.479407096811145	0.707725873425963
GO:0030170	pyridoxal phosphate binding	2/535	56/18639	0.0357142857142857	1.24425901201602	0.480584123508846	0.707725873425963
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/535	56/18639	0.0357142857142857	1.24425901201602	0.480584123508846	0.707725873425963
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:0017134	fibroblast growth factor binding	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:0031681	G-protein beta-subunit binding	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:0044013	histone H2B acetyltransferase activity	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:0070577	lysine-acetylated histone binding	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/535	23/18639	0.0434782608695652	1.51475010158472	0.488412290452503	0.711000186757087
GO:0070279	vitamin B6 binding	2/535	57/18639	0.0350877192982456	1.22242990654206	0.48989862892058	0.711996698005687
GO:0008083	growth factor activity	5/535	162/18639	0.0308641975308642	1.07528556593977	0.498373113623773	0.716766006012932
GO:0017116	single-stranded DNA helicase activity	2/535	58/18639	0.0344827586206897	1.20135352884306	0.499107519596323	0.716766006012932
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0005540	hyaluronic acid binding	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0035035	histone acetyltransferase binding	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0043998	histone H2A acetyltransferase activity	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0060229	lipase activator activity	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0070300	phosphatidic acid binding	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0140033	acetylation-dependent protein binding	1/535	24/18639	0.0416666666666667	1.45163551401869	0.503114666076048	0.716766006012932
GO:0031593	polyubiquitin modification-dependent protein binding	2/535	59/18639	0.0338983050847458	1.18099160462538	0.508209176369955	0.716766006012932
GO:0036002	pre-mRNA binding	2/535	59/18639	0.0338983050847458	1.18099160462538	0.508209176369955	0.716766006012932
GO:0008514	organic anion transmembrane transporter activity	8/535	269/18639	0.0297397769516729	1.03611159364903	0.509737958572437	0.716766006012932
GO:0004867	serine-type endopeptidase inhibitor activity	3/535	95/18639	0.0315789473684211	1.10018691588785	0.51593585762619	0.716766006012932
GO:0008276	protein methyltransferase activity	3/535	95/18639	0.0315789473684211	1.10018691588785	0.51593585762619	0.716766006012932
GO:0001098	basal transcription machinery binding	2/535	60/18639	0.0333333333333333	1.16130841121495	0.51720215954414	0.716766006012932
GO:0001099	basal RNA polymerase II transcription machinery binding	2/535	60/18639	0.0333333333333333	1.16130841121495	0.51720215954414	0.716766006012932
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/535	60/18639	0.0333333333333333	1.16130841121495	0.51720215954414	0.716766006012932
GO:0001848	complement binding	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0004709	MAP kinase kinase kinase activity	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0005537	D-mannose binding	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0015645	fatty acid ligase activity	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0015662	P-type ion transporter activity	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0042974	nuclear retinoic acid receptor binding	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0120020	cholesterol transfer activity	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0120515	fatty acid-CoA ligase activity	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0140358	P-type transmembrane transporter activity	1/535	25/18639	0.04	1.39357009345794	0.517395281367443	0.716766006012932
GO:0005525	GTP binding	11/535	378/18639	0.0291005291005291	1.0138406764575	0.524598609309324	0.725441036539249
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	5/535	167/18639	0.029940119760479	1.04309138731882	0.525291201007587	0.725441036539249
GO:0030594	neurotransmitter receptor activity	3/535	97/18639	0.0309278350515464	1.07750264958088	0.529990554207864	0.726909703066226
GO:0008157	protein phosphatase 1 binding	1/535	26/18639	0.0384615384615385	1.33997124370956	0.531266213164392	0.726909703066226
GO:0050681	nuclear androgen receptor binding	1/535	26/18639	0.0384615384615385	1.33997124370956	0.531266213164392	0.726909703066226
GO:0051139	metal cation:proton antiporter activity	1/535	26/18639	0.0384615384615385	1.33997124370956	0.531266213164392	0.726909703066226
GO:0097602	cullin family protein binding	1/535	26/18639	0.0384615384615385	1.33997124370956	0.531266213164392	0.726909703066226
GO:0120014	phospholipid transfer activity	1/535	26/18639	0.0384615384615385	1.33997124370956	0.531266213164392	0.726909703066226
GO:0003714	transcription corepressor activity	6/535	204/18639	0.0294117647058824	1.02468389224849	0.533642367136114	0.729037572333645
GO:0005249	voltage-gated potassium channel activity	3/535	98/18639	0.0306122448979592	1.06650772458516	0.536931902303442	0.732404806828659
GO:0022824	transmitter-gated monoatomic ion channel activity	2/535	63/18639	0.0317460317460317	1.10600801068091	0.543517177452637	0.736511749737773
GO:0022835	transmitter-gated channel activity	2/535	63/18639	0.0317460317460317	1.10600801068091	0.543517177452637	0.736511749737773
GO:0008320	protein transmembrane transporter activity	1/535	27/18639	0.037037037037037	1.29034267912773	0.544739193122328	0.736511749737773
GO:0016405	CoA-ligase activity	1/535	27/18639	0.037037037037037	1.29034267912773	0.544739193122328	0.736511749737773
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/535	27/18639	0.037037037037037	1.29034267912773	0.544739193122328	0.736511749737773
GO:0015297	antiporter activity	4/535	135/18639	0.0296296296296296	1.03227414330218	0.544919166191123	0.736511749737773
GO:0005244	voltage-gated monoatomic ion channel activity	5/535	173/18639	0.0289017341040462	1.00691480741181	0.556732371072384	0.746007753607614
GO:0140030	modification-dependent protein binding	5/535	173/18639	0.0289017341040462	1.00691480741181	0.556732371072384	0.746007753607614
GO:0005242	inward rectifier potassium channel activity	1/535	28/18639	0.0357142857142857	1.24425901201602	0.55782561756245	0.746007753607614
GO:0016866	intramolecular transferase activity	1/535	28/18639	0.0357142857142857	1.24425901201602	0.55782561756245	0.746007753607614
GO:0036408	histone H3K14 acetyltransferase activity	1/535	28/18639	0.0357142857142857	1.24425901201602	0.55782561756245	0.746007753607614
GO:0051393	alpha-actinin binding	1/535	28/18639	0.0357142857142857	1.24425901201602	0.55782561756245	0.746007753607614
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/535	28/18639	0.0357142857142857	1.24425901201602	0.55782561756245	0.746007753607614
GO:0160215	deacylase activity	2/535	65/18639	0.0307692307692308	1.07197699496765	0.560498049240093	0.748454537932635
GO:0008238	exopeptidase activity	3/535	102/18639	0.0294117647058824	1.02468389224849	0.564101030290681	0.752134707054242
GO:0003785	actin monomer binding	1/535	29/18639	0.0344827586206897	1.20135352884306	0.570536557039323	0.75531606480485
GO:0010484	histone H3 acetyltransferase activity	1/535	29/18639	0.0344827586206897	1.20135352884306	0.570536557039323	0.75531606480485
GO:0035250	UDP-galactosyltransferase activity	1/535	29/18639	0.0344827586206897	1.20135352884306	0.570536557039323	0.75531606480485
GO:0106222	lncRNA binding	1/535	29/18639	0.0344827586206897	1.20135352884306	0.570536557039323	0.75531606480485
GO:0005253	monoatomic anion channel activity	3/535	103/18639	0.029126213592233	1.0147355049451	0.570739954373935	0.75531606480485
GO:0016500	protein-hormone receptor activity	2/535	67/18639	0.0298507462686567	1.03997768168503	0.577022971041193	0.762494640304433
GO:0031210	phosphatidylcholine binding	1/535	30/18639	0.0333333333333333	1.16130841121495	0.58288276563599	0.764089376232176
GO:0043995	histone H4K5 acetyltransferase activity	1/535	30/18639	0.0333333333333333	1.16130841121495	0.58288276563599	0.764089376232176
GO:0043996	histone H4K8 acetyltransferase activity	1/535	30/18639	0.0333333333333333	1.16130841121495	0.58288276563599	0.764089376232176
GO:0043997	histone H4K12 acetyltransferase activity	1/535	30/18639	0.0333333333333333	1.16130841121495	0.58288276563599	0.764089376232176
GO:0051721	protein phosphatase 2A binding	1/535	30/18639	0.0333333333333333	1.16130841121495	0.58288276563599	0.764089376232176
GO:0020037	heme binding	4/535	142/18639	0.028169014084507	0.981387389759115	0.584992449829605	0.764089376232176
GO:0140223	general transcription initiation factor activity	2/535	68/18639	0.0294117647058824	1.02468389224849	0.585113486303918	0.764089376232176
GO:1990841	promoter-specific chromatin binding	2/535	68/18639	0.0294117647058824	1.02468389224849	0.585113486303918	0.764089376232176
GO:0016853	isomerase activity	5/535	180/18639	0.0277777777777778	0.967757009345794	0.592064971104136	0.772031856593939
GO:0098960	postsynaptic neurotransmitter receptor activity	2/535	69/18639	0.0289855072463768	1.00983340105648	0.593089086660608	0.772233297587419
GO:0016878	acid-thiol ligase activity	1/535	31/18639	0.032258064516129	1.12384684956286	0.594874689994351	0.772293457185649
GO:0047499	calcium-independent phospholipase A2 activity	1/535	31/18639	0.032258064516129	1.12384684956286	0.594874689994351	0.772293457185649
GO:0008378	galactosyltransferase activity	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0015106	bicarbonate transmembrane transporter activity	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0022884	macromolecule transmembrane transporter activity	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0042910	xenobiotic transmembrane transporter activity	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0047498	calcium-dependent phospholipase A2 activity	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0140142	nucleocytoplasmic carrier activity	1/535	32/18639	0.03125	1.08872663551402	0.606522478088344	0.779438437832778
GO:0004222	metalloendopeptidase activity	3/535	110/18639	0.0272727272727273	0.950161427357689	0.615419562447904	0.787490155564446
GO:0005518	collagen binding	2/535	72/18639	0.0277777777777778	0.967757009345794	0.616326082030304	0.787490155564446
GO:0042379	chemokine receptor binding	2/535	72/18639	0.0277777777777778	0.967757009345794	0.616326082030304	0.787490155564446
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/535	33/18639	0.0303030303030303	1.05573491928632	0.617835987747221	0.787490155564446
GO:0019956	chemokine binding	1/535	33/18639	0.0303030303030303	1.05573491928632	0.617835987747221	0.787490155564446
GO:0046982	protein heterodimerization activity	10/535	369/18639	0.02710027100271	0.944153179849556	0.618108827059031	0.787490155564446
GO:0015035	protein-disulfide reductase activity	1/535	34/18639	0.0294117647058824	1.02468389224849	0.628824794936044	0.797709168433153
GO:0051427	hormone receptor binding	1/535	34/18639	0.0294117647058824	1.02468389224849	0.628824794936044	0.797709168433153
GO:0090482	vitamin transmembrane transporter activity	1/535	34/18639	0.0294117647058824	1.02468389224849	0.628824794936044	0.797709168433153
GO:0046943	carboxylic acid transmembrane transporter activity	5/535	188/18639	0.0265957446808511	0.926575860011931	0.630469564023371	0.798496552296964
GO:0003678	DNA helicase activity	2/535	74/18639	0.027027027027027	0.941601414498611	0.6312438960726	0.798496552296964
GO:0005342	organic acid transmembrane transporter activity	5/535	189/18639	0.0264550264550265	0.92167334223409	0.635113129997535	0.798698176088121
GO:0046906	tetrapyrrole binding	4/535	152/18639	0.0263157894736842	0.916822429906542	0.638526008259509	0.798698176088121
GO:0003725	double-stranded RNA binding	2/535	75/18639	0.0266666666666667	0.929046728971963	0.63853159180101	0.798698176088121
GO:0019003	GDP binding	2/535	75/18639	0.0266666666666667	0.929046728971963	0.63853159180101	0.798698176088121
GO:0004623	phospholipase A2 activity	1/535	35/18639	0.0285714285714286	0.995407209612817	0.639498201800286	0.798698176088121
GO:0010485	histone H4 acetyltransferase activity	1/535	35/18639	0.0285714285714286	0.995407209612817	0.639498201800286	0.798698176088121
GO:0016229	steroid dehydrogenase activity	1/535	35/18639	0.0285714285714286	0.995407209612817	0.639498201800286	0.798698176088121
GO:0061631	ubiquitin conjugating enzyme activity	1/535	35/18639	0.0285714285714286	0.995407209612817	0.639498201800286	0.798698176088121
GO:0140566	histone reader activity	1/535	35/18639	0.0285714285714286	0.995407209612817	0.639498201800286	0.798698176088121
GO:0061775	cohesin loader activity	4/535	153/18639	0.0261437908496732	0.910830126443101	0.643625095687421	0.799280245289971
GO:0017022	myosin binding	2/535	76/18639	0.0263157894736842	0.916822429906542	0.645705701765312	0.799280245289971
GO:0051536	iron-sulfur cluster binding	2/535	76/18639	0.0263157894736842	0.916822429906542	0.645705701765312	0.799280245289971
GO:0098631	cell adhesion mediator activity	2/535	76/18639	0.0263157894736842	0.916822429906542	0.645705701765312	0.799280245289971
GO:0005506	iron ion binding	4/535	154/18639	0.025974025974026	0.904915645102561	0.648676767063789	0.799280245289971
GO:0000993	RNA polymerase II complex binding	1/535	36/18639	0.0277777777777778	0.967757009345794	0.64986524448126	0.799280245289971
GO:0005484	SNAP receptor activity	1/535	36/18639	0.0277777777777778	0.967757009345794	0.64986524448126	0.799280245289971
GO:0045505	dynein intermediate chain binding	1/535	36/18639	0.0277777777777778	0.967757009345794	0.64986524448126	0.799280245289971
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/535	36/18639	0.0277777777777778	0.967757009345794	0.64986524448126	0.799280245289971
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/535	36/18639	0.0277777777777778	0.967757009345794	0.64986524448126	0.799280245289971
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/535	36/18639	0.0277777777777778	0.967757009345794	0.64986524448126	0.799280245289971
GO:0009055	electron transfer activity	3/535	116/18639	0.0258620689655172	0.901015146632291	0.651139039953147	0.799474768080306
GO:0004857	enzyme inhibitor activity	11/535	416/18639	0.0264423076923077	0.921230230050324	0.651824022624033	0.799474768080306
GO:0051540	metal cluster binding	2/535	77/18639	0.025974025974026	0.904915645102561	0.65276672954594	0.799526697705924
GO:1990782	protein tyrosine kinase binding	3/535	117/18639	0.0256410256410256	0.893314162473041	0.656856599844484	0.803427907247798
GO:0008236	serine-type peptidase activity	5/535	194/18639	0.0257731958762887	0.897918874650737	0.657788059045618	0.803460517788871
GO:0042805	actinin binding	1/535	37/18639	0.027027027027027	0.941601414498611	0.659934700708886	0.804975294271279
GO:0005125	cytokine activity	6/535	234/18639	0.0256410256410256	0.893314162473041	0.666580039990731	0.811965810029861
GO:0140658	ATP-dependent chromatin remodeler activity	4/535	158/18639	0.0253164556962025	0.882006388264521	0.668405292951855	0.813073835809928
GO:0016791	phosphatase activity	7/535	273/18639	0.0256410256410256	0.893314162473041	0.67130487250777	0.815483894373324
GO:0017171	serine hydrolase activity	5/535	198/18639	0.0252525252525253	0.879779099405268	0.675264031144746	0.819172759093627
GO:0004540	RNA nuclease activity	3/535	121/18639	0.0247933884297521	0.863783115779717	0.679050261226374	0.819487321254244
GO:0000217	DNA secondary structure binding	1/535	39/18639	0.0256410256410256	0.893314162473041	0.679214716715229	0.819487321254244
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/535	39/18639	0.0256410256410256	0.893314162473041	0.679214716715229	0.819487321254244
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/535	39/18639	0.0256410256410256	0.893314162473041	0.679214716715229	0.819487321254244
GO:0015036	disulfide oxidoreductase activity	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:0030331	nuclear estrogen receptor binding	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:0050997	quaternary ammonium group binding	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:0061791	GTPase motor activity	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:0071855	neuropeptide receptor binding	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:1990606	membrane scission GTPase motor activity	1/535	40/18639	0.025	0.870981308411215	0.688441605239818	0.822794273826323
GO:0005254	chloride channel activity	2/535	83/18639	0.0240963855421687	0.839500056299966	0.692794008691883	0.826883171664505
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/535	41/18639	0.024390243902439	0.8497378618646	0.697403578528527	0.827164384807397
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/535	41/18639	0.024390243902439	0.8497378618646	0.697403578528527	0.827164384807397
GO:0017080	sodium channel regulator activity	1/535	41/18639	0.024390243902439	0.8497378618646	0.697403578528527	0.827164384807397
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/535	41/18639	0.024390243902439	0.8497378618646	0.697403578528527	0.827164384807397
GO:0005539	glycosaminoglycan binding	6/535	242/18639	0.0247933884297521	0.863783115779717	0.697687076825158	0.827164384807397
GO:0004860	protein kinase inhibitor activity	2/535	84/18639	0.0238095238095238	0.829506008010681	0.699082493035013	0.827713671753455
GO:0008168	methyltransferase activity	5/535	204/18639	0.0245098039215686	0.853903243540407	0.700348853972963	0.828108897906779
GO:0004402	histone acetyltransferase activity	1/535	42/18639	0.0238095238095238	0.829506008010681	0.706108228785933	0.831596959100674
GO:0016859	cis-trans isomerase activity	1/535	42/18639	0.0238095238095238	0.829506008010681	0.706108228785933	0.831596959100674
GO:0019894	kinesin binding	1/535	42/18639	0.0238095238095238	0.829506008010681	0.706108228785933	0.831596959100674
GO:0016874	ligase activity	4/535	167/18639	0.0239520958083832	0.834473109855056	0.709964547064824	0.834341010815777
GO:0004519	endonuclease activity	3/535	127/18639	0.0236220472440945	0.822974464640518	0.710317347045864	0.834341010815777
GO:0050660	flavin adenine dinucleotide binding	2/535	86/18639	0.0232558139534884	0.810215170615084	0.711339260848507	0.834437600572621
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/535	43/18639	0.0232558139534884	0.810215170615084	0.714562931028205	0.837113301785021
GO:0015291	secondary active transmembrane transporter activity	7/535	287/18639	0.024390243902439	0.8497378618646	0.720533453419633	0.840481362391741
GO:0003954	NADH dehydrogenase activity	1/535	44/18639	0.0227272727272727	0.791801189464741	0.722774849284814	0.840481362391741
GO:0016790	thiolester hydrolase activity	1/535	44/18639	0.0227272727272727	0.791801189464741	0.722774849284814	0.840481362391741
GO:0030547	signaling receptor inhibitor activity	1/535	44/18639	0.0227272727272727	0.791801189464741	0.722774849284814	0.840481362391741
GO:0043014	alpha-tubulin binding	1/535	44/18639	0.0227272727272727	0.791801189464741	0.722774849284814	0.840481362391741
GO:0004197	cysteine-type endopeptidase activity	2/535	88/18639	0.0227272727272727	0.791801189464741	0.723175603081465	0.840481362391741
GO:0008094	ATP-dependent activity, acting on DNA	5/535	210/18639	0.0238095238095238	0.829506008010681	0.724063335844236	0.840481362391741
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	2/535	89/18639	0.0224719101123595	0.782904546886485	0.728938671475841	0.841246538807458
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	2/535	89/18639	0.0224719101123595	0.782904546886485	0.728938671475841	0.841246538807458
GO:0031072	heat shock protein binding	3/535	131/18639	0.0229007633587786	0.797845473353785	0.729828617229061	0.841246538807458
GO:0008009	chemokine activity	1/535	45/18639	0.0222222222222222	0.774205607476635	0.730750942623487	0.841246538807458
GO:0046915	transition metal ion transmembrane transporter activity	1/535	45/18639	0.0222222222222222	0.774205607476635	0.730750942623487	0.841246538807458
GO:0051539	4 iron, 4 sulfur cluster binding	1/535	45/18639	0.0222222222222222	0.774205607476635	0.730750942623487	0.841246538807458
GO:0008201	heparin binding	4/535	172/18639	0.0232558139534884	0.810215170615084	0.731353972927205	0.841246538807458
GO:0019210	kinase inhibitor activity	2/535	90/18639	0.0222222222222222	0.774205607476635	0.734599756436801	0.842796619787958
GO:0140793	histone H2AXY142 phosphatase activity	2/535	90/18639	0.0222222222222222	0.774205607476635	0.734599756436801	0.842796619787958
GO:0003924	GTPase activity	8/535	331/18639	0.0241691842900302	0.842036310246492	0.737512250072096	0.843997681146763
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/535	46/18639	0.0217391304347826	0.757375050792361	0.738497971003418	0.843997681146763
GO:0030291	protein serine/threonine kinase inhibitor activity	1/535	46/18639	0.0217391304347826	0.757375050792361	0.738497971003418	0.843997681146763
GO:0016741	transferase activity, transferring one-carbon groups	5/535	215/18639	0.0232558139534884	0.810215170615084	0.742775905238131	0.84675851071683
GO:0004721	phosphoprotein phosphatase activity	4/535	175/18639	0.0228571428571429	0.796325767690254	0.743609253657697	0.84675851071683
GO:0051087	protein-folding chaperone binding	3/535	134/18639	0.0223880597014925	0.779983261263775	0.74377436752154	0.84675851071683
GO:0005504	fatty acid binding	1/535	47/18639	0.0212765957446809	0.741260688009545	0.746022500961637	0.84714575556769
GO:0061733	protein-lysine-acetyltransferase activity	1/535	47/18639	0.0212765957446809	0.741260688009545	0.746022500961637	0.84714575556769
GO:0004252	serine-type endopeptidase activity	4/535	176/18639	0.0227272727272727	0.791801189464741	0.747598719363766	0.847851421194156
GO:0051213	dioxygenase activity	2/535	93/18639	0.021505376344086	0.749231233041905	0.75098215302136	0.848318222491032
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/535	48/18639	0.0208333333333333	0.725817757009346	0.753330911137278	0.848318222491032
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/535	48/18639	0.0208333333333333	0.725817757009346	0.753330911137278	0.848318222491032
GO:0005004	GPI-linked ephrin receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0005008	hepatocyte growth factor receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0005009	insulin receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0005011	macrophage colony-stimulating factor receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0005020	stem cell factor receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0008288	boss receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0036332	placental growth factor receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0038062	protein tyrosine kinase collagen receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0060175	brain-derived neurotrophic factor receptor activity	1/535	49/18639	0.0204081632653061	0.711005149723441	0.760429397638357	0.848318222491032
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	4/535	181/18639	0.0220994475138122	0.769928228429803	0.76683660306116	0.849605602966237
GO:0005006	epidermal growth factor receptor activity	1/535	50/18639	0.02	0.696785046728972	0.767323979255543	0.849605602966237
GO:0005007	fibroblast growth factor receptor activity	1/535	50/18639	0.02	0.696785046728972	0.767323979255543	0.849605602966237
GO:0005017	platelet-derived growth factor receptor activity	1/535	50/18639	0.02	0.696785046728972	0.767323979255543	0.849605602966237
GO:0005019	platelet-derived growth factor beta-receptor activity	1/535	50/18639	0.02	0.696785046728972	0.767323979255543	0.849605602966237
GO:0015605	organophosphate ester transmembrane transporter activity	1/535	50/18639	0.02	0.696785046728972	0.767323979255543	0.849605602966237
GO:0005010	insulin-like growth factor receptor activity	1/535	51/18639	0.0196078431372549	0.683122594832325	0.774020502527278	0.853826343160525
GO:0005030	neurotrophin receptor activity	1/535	51/18639	0.0196078431372549	0.683122594832325	0.774020502527278	0.853826343160525
GO:0030544	Hsp70 protein binding	1/535	51/18639	0.0196078431372549	0.683122594832325	0.774020502527278	0.853826343160525
GO:0004725	protein tyrosine phosphatase activity	2/535	98/18639	0.0204081632653061	0.711005149723441	0.77635224919253	0.855335976777874
GO:0008237	metallopeptidase activity	4/535	184/18639	0.0217391304347826	0.757375050792361	0.77781920408507	0.855890276614055
GO:0004864	protein phosphatase inhibitor activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:0005003	ephrin receptor activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:0005005	transmembrane-ephrin receptor activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:0034212	protein N-acetyltransferase activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:0038064	collagen receptor activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/535	53/18639	0.0188679245283019	0.657344383706577	0.786841928310913	0.857953288313114
GO:0008234	cysteine-type peptidase activity	4/535	187/18639	0.0213903743315508	0.745224648907991	0.788389508179618	0.857953288313114
GO:0031406	carboxylic acid binding	4/535	187/18639	0.0213903743315508	0.745224648907991	0.788389508179618	0.857953288313114
GO:0140463	chromatin-protein adaptor activity	1/535	54/18639	0.0185185185185185	0.645171339563863	0.792977706227283	0.860769977269313
GO:0000287	magnesium ion binding	5/535	230/18639	0.0217391304347826	0.757375050792361	0.793271130608341	0.860769977269313
GO:0015293	symporter activity	3/535	146/18639	0.0205479452054795	0.715875048009218	0.793885823630143	0.860769977269313
GO:0043177	organic acid binding	4/535	189/18639	0.0211640211640212	0.737338673787272	0.795210862237319	0.861155177642365
GO:0008374	O-acyltransferase activity	1/535	55/18639	0.0181818181818182	0.633440951571793	0.798937185762844	0.864136688133259
GO:0019212	phosphatase inhibitor activity	1/535	56/18639	0.0178571428571429	0.622129506008011	0.804725423258372	0.868642306978523
GO:0008509	monoatomic anion transmembrane transporter activity	3/535	149/18639	0.0201342281879195	0.701461456438562	0.805059255228969	0.868642306978523
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/535	57/18639	0.0175438596491228	0.611214953271028	0.810347330300118	0.870056561658614
GO:0000510	H3-H4 histone complex chaperone activity	3/535	151/18639	0.0198675496688742	0.692170576220833	0.812222060429729	0.870056561658614
GO:0140584	chromatin extrusion motor activity	3/535	151/18639	0.0198675496688742	0.692170576220833	0.812222060429729	0.870056561658614
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/535	151/18639	0.0198675496688742	0.692170576220833	0.812222060429729	0.870056561658614
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/535	151/18639	0.0198675496688742	0.692170576220833	0.812222060429729	0.870056561658614
GO:0004497	monooxygenase activity	2/535	106/18639	0.0188679245283019	0.657344383706577	0.812248749566431	0.870056561658614
GO:0015616	DNA translocase activity	3/535	152/18639	0.0197368421052632	0.687616822429907	0.815719296379465	0.870717810019731
GO:0140674	ATP-dependent histone chaperone activity	3/535	152/18639	0.0197368421052632	0.687616822429907	0.815719296379465	0.870717810019731
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/535	58/18639	0.0172413793103448	0.600676764421528	0.815807677856325	0.870717810019731
GO:0004843	cysteine-type deubiquitinase activity	2/535	108/18639	0.0185185185185185	0.645171339563863	0.820381142517242	0.874547964652234
GO:0004386	helicase activity	3/535	155/18639	0.0193548387096774	0.674308109737715	0.825881198782067	0.878707478048962
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/535	60/18639	0.0166666666666667	0.580654205607477	0.826262099291535	0.878707478048962
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/535	61/18639	0.0163934426229508	0.571135284204075	0.831265047613782	0.881915606070536
GO:0016836	hydro-lyase activity	1/535	61/18639	0.0163934426229508	0.571135284204075	0.831265047613782	0.881915606070536
GO:0003689	DNA clamp loader activity	3/535	160/18639	0.01875	0.653235981308411	0.841753334763528	0.891977280751806
GO:0101005	deubiquitinase activity	2/535	115/18639	0.0173913043478261	0.605900040633889	0.846411816896651	0.895844688205275
GO:0015294	solute:monoatomic cation symporter activity	2/535	116/18639	0.0172413793103448	0.600676764421528	0.849837655088642	0.898399806807993
GO:0140713	histone chaperone activity	3/535	164/18639	0.0182926829268293	0.63730339639845	0.853535737824599	0.899801560411327
GO:0004518	nuclease activity	4/535	209/18639	0.0191387559808612	0.66677994902294	0.854073392604759	0.899801560411327
GO:0008235	metalloexopeptidase activity	1/535	66/18639	0.0151515151515152	0.527867459643161	0.854203508363456	0.899801560411327
GO:0008173	RNA methyltransferase activity	1/535	67/18639	0.0149253731343284	0.519988840842516	0.858403213474399	0.903154091901974
GO:0003777	microtubule motor activity	1/535	68/18639	0.0147058823529412	0.512341946124244	0.862482164626197	0.905178963356777
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/535	68/18639	0.0147058823529412	0.512341946124244	0.862482164626197	0.905178963356777
GO:0015108	chloride transmembrane transporter activity	2/535	121/18639	0.0165289256198347	0.575855410519811	0.865945338498168	0.905178963356777
GO:0051082	unfolded protein binding	2/535	121/18639	0.0165289256198347	0.575855410519811	0.865945338498168	0.905178963356777
GO:0002039	p53 binding	1/535	69/18639	0.0144927536231884	0.504916700528241	0.866443827537456	0.905178963356777
GO:0008080	N-acetyltransferase activity	1/535	69/18639	0.0144927536231884	0.504916700528241	0.866443827537456	0.905178963356777
GO:0019783	ubiquitin-like protein peptidase activity	2/535	127/18639	0.015748031496063	0.548649643093679	0.883176849592842	0.920904226085093
GO:0031491	nucleosome binding	1/535	74/18639	0.0135135135135135	0.470800707249305	0.88460732528219	0.920904226085093
GO:0035064	methylated histone binding	1/535	74/18639	0.0135135135135135	0.470800707249305	0.88460732528219	0.920904226085093
GO:0031490	chromatin DNA binding	2/535	128/18639	0.015625	0.544363317757009	0.885841651314156	0.921109351717764
GO:0044183	protein folding chaperone	1/535	75/18639	0.0133333333333333	0.464523364485981	0.887932673031935	0.922203758657729
GO:0140034	methylation-dependent protein binding	1/535	76/18639	0.0131578947368421	0.458411214953271	0.891162365982157	0.924476846953453
GO:1901681	sulfur compound binding	5/535	275/18639	0.0181818181818182	0.633440951571793	0.899207446069229	0.930699040746446
GO:0016835	carbon-oxygen lyase activity	1/535	79/18639	0.0126582278481013	0.441003194132261	0.900304590091439	0.930699040746446
GO:0033293	monocarboxylic acid binding	1/535	79/18639	0.0126582278481013	0.441003194132261	0.900304590091439	0.930699040746446
GO:0140789	histone phosphatase activity	2/535	136/18639	0.0147058823529412	0.512341946124244	0.905216482340618	0.934688646881941
GO:0140597	protein carrier chaperone	3/535	188/18639	0.0159574468085106	0.555945516007158	0.909337101009038	0.937852898601656
GO:0004527	exonuclease activity	1/535	84/18639	0.0119047619047619	0.41475300400534	0.913869944997442	0.941434467700381
GO:0140097	catalytic activity, acting on DNA	6/535	336/18639	0.0178571428571429	0.622129506008011	0.923073407958628	0.949032396571694
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/535	88/18639	0.0113636363636364	0.39590059473237	0.923382872340027	0.949032396571694
GO:0003727	single-stranded RNA binding	1/535	89/18639	0.0112359550561798	0.391452273443243	0.925592465531666	0.95020359467297
GO:0052689	carboxylic ester hydrolase activity	1/535	92/18639	0.0108695652173913	0.37868752539618	0.931846857498298	0.955519641407031
GO:0016410	N-acyltransferase activity	1/535	94/18639	0.0106382978723404	0.370630344004772	0.935722093612887	0.95838664259313
GO:0016407	acetyltransferase activity	1/535	96/18639	0.0104166666666667	0.362908878504673	0.939377369453856	0.961022009303023
GO:0004175	endopeptidase activity	7/535	405/18639	0.0172839506172839	0.602159916926272	0.947977026698793	0.968703797132944
GO:0004722	protein serine/threonine phosphatase activity	1/535	103/18639	0.00970873786407767	0.338245168315035	0.950612328858836	0.97028017014557
GO:0015103	inorganic anion transmembrane transporter activity	2/535	165/18639	0.0121212121212121	0.422293967714528	0.952569238510391	0.971161290237918
GO:0019888	protein phosphatase regulator activity	1/535	107/18639	0.00934579439252336	0.325600489125688	0.956072467016767	0.973615081090469
GO:0019208	phosphatase regulator activity	1/535	117/18639	0.00854700854700855	0.297771387491014	0.967229451946433	0.983848514694653
GO:0003697	single-stranded DNA binding	1/535	121/18639	0.00826446280991736	0.287927705259906	0.970855075225173	0.985008014797374
GO:0008528	G protein-coupled peptide receptor activity	1/535	122/18639	0.00819672131147541	0.285567642102038	0.97169709567849	0.985008014797374
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/535	122/18639	0.00819672131147541	0.285567642102038	0.97169709567849	0.985008014797374
GO:0001653	peptide receptor activity	1/535	128/18639	0.0078125	0.272181658878505	0.976263059852581	0.987382229099193
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	1/535	128/18639	0.0078125	0.272181658878505	0.976263059852581	0.987382229099193
GO:0005179	hormone activity	1/535	132/18639	0.00757575757575758	0.26393372982158	0.978890727850531	0.988913499808045
GO:0140767	enzyme-substrate adaptor activity	1/535	139/18639	0.00719424460431655	0.250642103139918	0.982809786111042	0.991744420530234
GO:0140098	catalytic activity, acting on RNA	5/535	387/18639	0.0129198966408269	0.450119539230602	0.987580581997635	0.995427419766061
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/535	229/18639	0.00873362445414847	0.304272946169857	0.990438291683986	0.997175967137618
GO:0005201	extracellular matrix structural constituent	1/535	168/18639	0.00595238095238095	0.20737650200267	0.992664893045933	0.997740882566035
GO:0003735	structural constituent of ribosome	1/535	175/18639	0.00571428571428571	0.199081441922563	0.994029124332717	0.997740882566035
GO:0043021	ribonucleoprotein complex binding	1/535	177/18639	0.00564971751412429	0.196831934104229	0.99437013634115	0.997740882566035
GO:0003730	mRNA 3'-UTR binding	1/535	262/18639	0.00381679389312977	0.132974245558964	0.999540338667202	0.99993673187521
GO:0045182	translation regulator activity	2/535	356/18639	0.00561797752808989	0.195726136721621	0.99966693123786	0.99993673187521
GO:0030371	translation repressor activity	1/535	329/18639	0.00303951367781155	0.105894384001364	0.99993673187521	0.99993673187521