category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 4/16 82/9376 28.5853658536585 HLA-B/CD74/HLA-DPA1/HLA-DPB1 10.3727054480673 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 3/16 37/9376 47.5135135135135 HBB/HBA2/HBA1 11.7202675470858 Human Diseases Immune disease hsa05330 Allograft rejection 3/16 39/9376 45.0769230769231 HLA-B/HLA-DPA1/HLA-DPB1 11.4037476645338 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 3/16 44/9376 39.9545454545455 HLA-B/HLA-DPA1/HLA-DPB1 10.7079126420638 Human Diseases Immune disease hsa05332 Graft-versus-host disease 3/16 45/9376 39.0666666666667 HLA-B/HLA-DPA1/HLA-DPB1 10.5826569101383 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/16 50/9376 35.16 HBB/HBA2/HBA1 10.0129688198471 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 3/16 54/9376 32.5555555555556 HLA-B/HLA-DPA1/HLA-DPB1 9.61448146168176 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 4/16 180/9376 13.0222222222222 HLA-B/CD74/HLA-DPA1/HLA-DPB1 6.73331958148404 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 3/16 70/9376 25.1142857142857 HLA-B/HLA-DPA1/HLA-DPB1 8.37239295028518 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 3/16 95/9376 18.5052631578947 LTB/HLA-DPA1/HLA-DPB1 7.08991070452433 Human Diseases Immune disease hsa05310 Asthma 2/16 32/9376 36.625 HLA-DPA1/HLA-DPB1 8.34586109941807 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/16 155/9376 11.341935483871 HLA-B/HLA-DPA1/HLA-DPB1 5.36767691524823 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 3/16 160/9376 10.9875 HLA-B/HLA-DPA1/HLA-DPB1 5.26809084830631 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 2/16 50/9376 23.44 HLA-DPA1/HLA-DPB1 6.57760598118763 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 3/16 181/9376 9.71270718232044 CD74/HLA-DPA1/HLA-DPB1 4.89355241324066 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 3/16 205/9376 8.57560975609756 HLA-B/HLA-DPA1/HLA-DPB1 4.53412912117239 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/16 66/9376 17.7575757575758 HLA-DPA1/HLA-DPB1 5.64827747919539 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 3/16 224/9376 7.84821428571429 HLA-B/HLA-DPA1/HLA-DPB1 4.28895065730545 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/16 78/9376 15.025641025641 HLA-DPA1/HLA-DPB1 5.14260247957969 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/16 93/9376 12.6021505376344 HLA-DPA1/HLA-DPB1 4.64882823692559 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 2/16 99/9376 11.8383838383838 HLA-DPA1/HLA-DPB1 4.48214654210904 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 2/16 100/9376 11.72 HLA-DPA1/HLA-DPB1 4.45576338656593 Organismal Systems Immune system hsa04659 Th17 cell differentiation 2/16 109/9376 10.7522935779817 HLA-DPA1/HLA-DPB1 4.23407102816749 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/16 112/9376 10.4642857142857 HLA-DPA1/HLA-DPB1 4.16586590077119 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 2/16 143/9376 8.19580419580419 HLA-DPA1/HLA-DPB1 3.58495446207615 Metabolism Glycan biosynthesis and metabolism hsa00604 Glycosphingolipid biosynthesis - ganglio series 1/16 15/9376 39.0666666666667 ST8SIA1 6.1001014990076 Metabolism Glycan biosynthesis and metabolism hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series 1/16 16/9376 36.625 ST8SIA1 5.89636887643757 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/16 173/9376 6.77456647398844 HLA-DPA1/HLA-DPB1 3.1694611359609 Metabolism Glycan biosynthesis and metabolism hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1/16 28/9376 20.9285714285714 ST8SIA1 4.366199107849 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 2/16 298/9376 3.93288590604027 TNFRSF25/LTB 2.12723718750648 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/16 65/9376 9.01538461538462 SPP1 2.68096155851806 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/16 333/9376 3.51951951951952 HLA-B/SPP1 1.93549156873757 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/16 89/9376 6.58426966292135 SPP1 2.18842349027686 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/16 105/9376 5.58095238095238 LTB 1.95161811886993 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/16 109/9376 5.37614678899083 SPP1 1.89995473230093 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/16 109/9376 5.37614678899083 TBC1D4 1.89995473230093 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/16 122/9376 4.80327868852459 TBC1D4 1.74815937189377 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/16 133/9376 4.40601503759398 HLA-B 1.63558684988578 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/16 138/9376 4.2463768115942 FYB1 1.58839019304143 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/16 140/9376 4.18571428571429 SPP1 1.57013351521341 NA NA hsa04518 Integrin signaling 1/16 154/9376 3.80519480519481 SPP1 1.45117080516615 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/16 157/9376 3.73248407643312 HLA-B 1.42749062151271 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/16 196/9376 2.98979591836735 HLA-B 1.16391947749262 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/16 203/9376 2.88669950738916 SPP1 1.12357680066396 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/16 204/9376 2.87254901960784 ANK3 1.11795406988792 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/16 205/9376 2.85853658536585 HLA-B 1.11236522547758 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/16 205/9376 2.85853658536585 TBC1D4 1.11236522547758 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/16 212/9376 2.76415094339623 FYB1 1.07415965553079 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/16 214/9376 2.73831775700935 HLA-B 1.06352723199369 Genetic Information Processing Translation hsa03010 Ribosome 1/16 222/9376 2.63963963963964 RPL13 1.02217945454372 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/16 227/9376 2.58149779735683 HLA-B 0.997246248759242 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/16 233/9376 2.51502145922747 ANK3 0.968188879655745 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/16 238/9376 2.46218487394958 RPL13 0.944654273741651 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/16 250/9376 2.344 HLA-B 0.890505786794317 NA NA hsa04517 IgSF CAM signaling 1/16 299/9376 1.95986622073579 ANK3 0.69740144037304 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/16 323/9376 1.81424148606811 FOXP1 0.61569543318352 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/16 362/9376 1.61878453038674 SPP1 0.496412445783599