category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	4/40	50/9376	18.752	HBB/HBA2/HBA1/PECAM1	8.23796226295699
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	5/40	155/9376	7.56129032258064	ITGB5/HLA-B/CYBA/HLA-DRB1/TCIRG1	5.39139690726988
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/40	37/9376	19.0054054054054	HBB/HBA2/HBA1	7.18271758639091
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/40	181/9376	6.47513812154696	ITGAX/CD74/HLA-DRB1/TCIRG1/KSR1	4.86848361379711
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/40	232/9376	5.05172413793103	PFN1/TMSB4X/ITGB5/ITGAX/ARHGEF1	4.09026046821313
NA	NA	hsa04518	Integrin signaling	4/40	154/9376	6.08831168831169	SPP1/FRAS1/ITGB5/ITGAX	4.16731875240882
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/40	160/9376	5.86	PECAM1/HLA-B/HLA-DRB1/PTPRD	4.05845037432689
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/40	82/9376	8.57560975609756	HLA-B/CD74/HLA-DRB1	4.50981159777624
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	3/40	89/9376	7.90112359550562	SPP1/FRAS1/ITGB5	4.28166118978477
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/40	95/9376	7.4021052631579	LTB/HLA-DRB1/TCIRG1	4.1050876949597
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/40	39/9376	12.0205128205128	HLA-B/HLA-DRB1	4.51404246790887
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/40	44/9376	10.6545454545455	HLA-B/HLA-DRB1	4.20151595524705
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/40	45/9376	10.4177777777778	HLA-B/HLA-DRB1	4.14501219973883
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/40	54/9376	8.68148148148148	HLA-B/HLA-DRB1	3.70529278567687
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/40	142/9376	4.95211267605634	CYBA/LILRB1/JUNB	3.10608808324937
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	2/40	59/9376	7.94576271186441	ENTPD1/NT5C	3.50302400055203
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/40	70/9376	6.69714285714286	HLA-B/HLA-DRB1	3.13155337176939
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/40	180/9376	3.90666666666667	HLA-B/CD74/HLA-DRB1	2.57731329354006
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/40	78/9376	6.01025641025641	CYBA/HLA-DRB1	2.90835686699664
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/40	79/9376	5.93417721518987	TCIRG1/NSF	2.88265113327556
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	2/40	85/9376	5.51529411764706	ENTPD1/NT5C	2.7371556205066
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/40	333/9376	2.81561561561562	SPP1/ITGB5/HLA-B/TCIRG1	2.20813170243511
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/40	205/9376	3.43024390243902	ENTPD1/HLA-B/HLA-DRB1	2.30278641272093
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/40	109/9376	4.30091743119266	RUNX1/HLA-DRB1	2.26889052181174
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/40	116/9376	4.04137931034483	PECAM1/CYBA	2.1573931767872
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/40	128/9376	3.6625	ENTPD1/NT5C	1.98520748084564
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/40	134/9376	3.49850746268657	ARHGEF1/ACTG2	1.90671279272162
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/40	28/9376	8.37142857142857	TCIRG1	2.55685757874547
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	1/40	30/9376	7.81333333333333	IDH2	2.44648517331137
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/40	142/9376	3.30140845070423	PECAM1/CYBA	1.80874837064486
Human Diseases	Immune disease	hsa05310	Asthma	1/40	32/9376	7.325	HLA-DRB1	2.34587202623754
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/40	33/9376	7.1030303030303	IDH2	2.2987647780479
NA	NA	hsa04517	IgSF CAM signaling	3/40	299/9376	2.35183946488294	ITGAX/SLAMF7/PTPRD	1.55497982847295
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/40	157/9376	2.9859872611465	PECAM1/ITGB5	1.64255374785939
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/40	38/9376	6.16842105263158	NT5C	2.08957499533744
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/40	42/9376	5.58095238095238	FTH1	1.94751914901517
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/40	44/9376	5.32727272727273	NSF	1.8831653434064
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/40	46/9376	5.09565217391304	FTH1	1.82262101358773
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/40	50/9376	4.688	HLA-DRB1	1.71144686941107
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/40	51/9376	4.59607843137255	TCIRG1	1.6854855570213
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/40	362/9376	1.94254143646409	EFNA5/SPP1/ITGB5	1.19710204500436
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/40	195/9376	2.40410256410256	CYBA/HDAC10	1.29689960137728
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/40	203/9376	2.30935960591133	SPP1/ITGB5	1.23448686461139
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/40	204/9376	2.29803921568627	ITGB5/ARHGEF1	1.22689129864739
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/40	205/9376	2.28682926829268	HLA-B/HDAC10	1.21933973439539
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/40	59/9376	3.9728813559322	IDH2	1.49934214176873
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/40	212/9376	2.21132075471698	EFNA5/PFN1	1.16766902843713
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/40	61/9376	3.84262295081967	FTH1	1.45790074660008
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/40	216/9376	2.17037037037037	CYBA/ARHGEF1	1.13903657458859
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/40	65/9376	3.60615384615385	DGKG	1.38004668018626
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/40	65/9376	3.60615384615385	SPP1	1.38004668018626
Genetic Information Processing	Translation	hsa03010	Ribosome	2/40	222/9376	2.11171171171171	RPL13/RPS2	1.09723190254135
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/40	66/9376	3.55151515151515	HLA-DRB1	1.36154027107096
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/40	224/9376	2.09285714285714	HLA-B/HLA-DRB1	1.08358905804139
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/40	227/9376	2.06519823788546	HLA-B/ARHGEF1	1.06338802778402
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/40	68/9376	3.44705882352941	CYP26A1	1.32557984036331
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/40	68/9376	3.44705882352941	RUNX1	1.32557984036331
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/40	70/9376	3.34857142857143	EGLN3	1.29094125957595
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/40	233/9376	2.01201716738197	ITGB5/ACTG2	1.02389799534158
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/40	71/9376	3.30140845070423	TCIRG1	1.27408939679911
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/40	71/9376	3.30140845070423	IDH2	1.27408939679911
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/40	238/9376	1.96974789915966	EFNA5/KSR1	0.991875039606701
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/40	238/9376	1.96974789915966	RPL13/RPS2	0.991875039606701
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/40	75/9376	3.12533333333333	IDH2	1.20956183592784
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/40	77/9376	3.04415584415584	RUNX1	1.17889860535564
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/40	83/9376	2.82409638554217	IDH2	1.09255692164162
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/40	86/9376	2.72558139534884	ITGB5	1.05223327306936
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/40	88/9376	2.66363636363636	ITGAX	1.02629886739933
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/40	89/9376	2.63370786516854	NSF	1.01360067892332
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/40	91/9376	2.57582417582418	LILRB1	0.988718620941649
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/40	93/9376	2.52043010752688	HLA-DRB1	0.964492760794284
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/40	98/9376	2.39183673469388	DGKG	0.90658673598301
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/40	99/9376	2.36767676767677	HLA-DRB1	0.895431774058924
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/40	99/9376	2.36767676767677	DGKG	0.895431774058924
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/40	99/9376	2.36767676767677	ITGB5	0.895431774058924
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/40	100/9376	2.344	HLA-DRB1	0.884410950177256
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/40	104/9376	2.25384615384615	DGKG	0.841607161965547
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/40	105/9376	2.23238095238095	LTB	0.831211510433185
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/40	105/9376	2.23238095238095	KSR1	0.831211510433185
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/40	105/9376	2.23238095238095	ITGB5	0.831211510433185
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/40	298/9376	1.57315436241611	TNFRSF18/LTB	0.658142380113304
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/40	109/9376	2.15045871559633	SPP1	0.790769514828217
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/40	110/9376	2.13090909090909	EGLN3	0.780931789701636
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/40	112/9376	2.09285714285714	HLA-DRB1	0.761567400807522
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/40	115/9376	2.03826086956522	ARHGEF1	0.733266217329827
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/40	116/9376	2.02068965517241	IDH2	0.724023106948992
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/40	119/9376	1.96974789915966	JUNB	0.696838935429903
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/40	122/9376	1.92131147540984	JUNB	0.670435281175384
Organismal Systems	Immune system	hsa04611	Platelet activation	1/40	126/9376	1.86031746031746	ARHGEF1	0.636368033341458
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/40	133/9376	1.76240601503759	HLA-B	0.579616673849507
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/40	138/9376	1.69855072463768	TCIRG1	0.541107712553011
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/40	138/9376	1.69855072463768	ARHGEF1	0.541107712553011
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/40	140/9376	1.67428571428571	SPP1	0.526139886388237
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/40	142/9376	1.65070422535211	HERC1	0.511408658040346
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/40	143/9376	1.63916083916084	HLA-DRB1	0.504129337371786
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/40	149/9376	1.57315436241611	DGKG	0.461604132868171
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/40	157/9376	1.49299363057325	HLA-B	0.407741052226803
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/40	168/9376	1.3952380952381	FTH1	0.338349855652098
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/40	170/9376	1.37882352941176	RUNX1	0.326257973071558
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/40	173/9376	1.35491329479769	HLA-DRB1	0.308401030758043
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/40	184/9376	1.27391304347826	EFNA5	0.245613271283515
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/40	187/9376	1.25347593582888	CYBA	0.229170453935145
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/40	191/9376	1.22722513089005	HDAC10	0.207667568484862
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/40	194/9376	1.20824742268041	ACTG2	0.191843490795922
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/40	196/9376	1.19591836734694	HLA-B	0.181433325327465
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/40	200/9376	1.172	ARHGEF1	0.160935537430314
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/40	201/9376	1.16616915422886	RUNX1	0.155876488608175
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/40	205/9376	1.14341463414634	CYBA	0.135893056069842
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/40	214/9376	1.09532710280374	HLA-B	0.0923343612926931
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	1/40	227/9376	1.03259911894273	CYBA	0.0325437196261446
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/40	248/9376	0.945161290322581	PFN1	-0.0572875783996319
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/40	250/9376	0.9376	TCIRG1	-0.0654560168790667
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/40	250/9376	0.9376	HLA-B	-0.0654560168790667
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/40	253/9376	0.926482213438735	PFN1	-0.0775923773747797
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/40	275/9376	0.852363636363636	CYBA	-0.162648604638398
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/40	300/9376	0.781333333333333	EFNA5	-0.251959756957879
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/40	323/9376	0.725696594427245	EFNA5	-0.328376003427364
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	1/40	368/9376	0.63695652173913	PFN1	-0.465054201566724
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/40	370/9376	0.633513513513513	GZMA	-0.470790909573221
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/40	449/9376	0.522048997772828	OR5V1	-0.679342823751809