ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031720 haptoglobin binding 3/79 10/18639 0.3 70.7810126582279 8.60771157290377e-06 0.00114511308571117 GO:0003823 antigen binding 7/79 174/18639 0.0402298850574713 9.49170667830642 9.01634067897198e-06 0.00114511308571117 GO:0019825 oxygen binding 4/79 34/18639 0.117647058823529 27.7572598659717 1.25836602825404e-05 0.00114511308571117 GO:0005344 oxygen carrier activity 3/79 14/18639 0.214285714285714 50.5578661844485 2.57925172443264e-05 0.00176033930192528 GO:0034987 immunoglobulin receptor binding 3/79 19/18639 0.157894736842105 37.253164556962 6.76205006350855e-05 0.00369207933467567 GO:0020037 heme binding 5/79 142/18639 0.0352112676056338 8.30763059368872 0.000342795243956282 0.0155684521174321 GO:0046906 tetrapyrrole binding 5/79 152/18639 0.0328947368421053 7.76107594936709 0.000468361177778154 0.0155684521174321 GO:0005506 iron ion binding 5/79 154/18639 0.0324675324675325 7.66028275521946 0.000497152077086002 0.0155684521174321 GO:0023023 MHC protein complex binding 3/79 37/18639 0.0810810810810811 19.1300034211427 0.000513245674201057 0.0155684521174321 GO:0004601 peroxidase activity 3/79 57/18639 0.0526315789473684 12.4177215189873 0.00181870875042627 0.0486103357069937 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/79 59/18639 0.0508474576271186 11.9967818064793 0.00200842624510913 0.0486103357069937 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/79 17/18639 0.117647058823529 27.7572598659717 0.00231477789080922 0.0486103357069937 GO:0019198 transmembrane receptor protein phosphatase activity 2/79 17/18639 0.117647058823529 27.7572598659717 0.00231477789080922 0.0486103357069937 GO:0140104 molecular carrier activity 5/79 249/18639 0.0200803212851406 4.73768491688272 0.00412660766710987 0.0804688495086424 GO:0008198 ferrous iron binding 2/79 26/18639 0.0769230769230769 18.1489776046738 0.00539679688654773 0.0935638749081451 GO:0023026 MHC class II protein complex binding 2/79 27/18639 0.0740740740740741 17.4767932489451 0.00581260529229616 0.0935638749081451 GO:0016209 antioxidant activity 3/79 86/18639 0.0348837209302326 8.23035030909626 0.00582632188072698 0.0935638749081451 GO:0003785 actin monomer binding 2/79 29/18639 0.0689655172413793 16.271497162811 0.00668671600248887 0.101415192704414 GO:0042287 MHC protein binding 2/79 41/18639 0.0487804878048781 11.5091077493053 0.0130698602971721 0.186814047031394 GO:0035198 miRNA binding 2/79 42/18639 0.0476190476190476 11.2350813743219 0.0136860107715307 0.186814047031394 GO:0042605 peptide antigen binding 2/79 45/18639 0.0444444444444444 10.4860759493671 0.015608497040687 0.202910461528931 GO:0005085 guanyl-nucleotide exchange factor activity 4/79 230/18639 0.0173913043478261 4.1032471106219 0.0165118672872797 0.204897262246698 GO:0140463 chromatin-protein adaptor activity 2/79 54/18639 0.037037037037037 8.73839662447257 0.0220162067312557 0.259180477080581 GO:0140313 molecular sequestering activity 2/79 55/18639 0.0363636363636364 8.5795166858458 0.022785096886205 0.259180477080581 GO:0061980 regulatory RNA binding 2/79 58/18639 0.0344827586206897 8.1357485814055 0.0251573136802324 0.274717865388137 GO:0140375 immune receptor activity 3/79 156/18639 0.0192307692307692 4.53724440116845 0.028637823396909 0.276592997815047 GO:0005178 integrin binding 3/79 161/18639 0.0186335403726708 4.39633618995204 0.0310338412557674 0.276592997815047 GO:0004252 serine-type endopeptidase activity 3/79 176/18639 0.0170454545454545 4.02164844649022 0.038834648918236 0.276592997815047 GO:0004382 GDP phosphatase activity 1/79 10/18639 0.1 23.593670886076 0.0415947787653639 0.276592997815047 GO:0005031 tumor necrosis factor receptor activity 1/79 10/18639 0.1 23.593670886076 0.0415947787653639 0.276592997815047 GO:0008401 retinoic acid 4-hydroxylase activity 1/79 10/18639 0.1 23.593670886076 0.0415947787653639 0.276592997815047 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/79 10/18639 0.1 23.593670886076 0.0415947787653639 0.276592997815047 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/79 10/18639 0.1 23.593670886076 0.0415947787653639 0.276592997815047 GO:0032395 MHC class II receptor activity 1/79 10/18639 0.1 23.593670886076 0.0415947787653639 0.276592997815047 GO:0033293 monocarboxylic acid binding 2/79 79/18639 0.0253164556962025 5.97308123698125 0.04430459774176 0.276592997815047 GO:0031406 carboxylic acid binding 3/79 187/18639 0.0160427807486631 3.78508089081432 0.0451310563835601 0.276592997815047 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/79 11/18639 0.0909090909090909 21.4487917146145 0.0456590877716199 0.276592997815047 GO:0008199 ferric iron binding 1/79 11/18639 0.0909090909090909 21.4487917146145 0.0456590877716199 0.276592997815047 GO:0042608 T cell receptor binding 1/79 11/18639 0.0909090909090909 21.4487917146145 0.0456590877716199 0.276592997815047 GO:0050998 nitric-oxide synthase binding 1/79 11/18639 0.0909090909090909 21.4487917146145 0.0456590877716199 0.276592997815047 GO:0043177 organic acid binding 3/79 189/18639 0.0158730158730159 3.74502712477396 0.0463273493733678 0.276592997815047 GO:0008236 serine-type peptidase activity 3/79 194/18639 0.0154639175257732 3.64850580712515 0.0493865237601216 0.276592997815047 GO:0051117 ATPase binding 2/79 84/18639 0.0238095238095238 5.61754068716094 0.0494588846100275 0.276592997815047 GO:0005078 MAP-kinase scaffold activity 1/79 12/18639 0.0833333333333333 19.6613924050633 0.0497063785202799 0.276592997815047 GO:0005165 neurotrophin receptor binding 1/79 12/18639 0.0833333333333333 19.6613924050633 0.0497063785202799 0.276592997815047 GO:0015166 polyol transmembrane transporter activity 1/79 12/18639 0.0833333333333333 19.6613924050633 0.0497063785202799 0.276592997815047 GO:0031543 peptidyl-proline dioxygenase activity 1/79 12/18639 0.0833333333333333 19.6613924050633 0.0497063785202799 0.276592997815047 GO:0045295 gamma-catenin binding 1/79 12/18639 0.0833333333333333 19.6613924050633 0.0497063785202799 0.276592997815047 GO:0017171 serine hydrolase activity 3/79 198/18639 0.0151515151515152 3.57479861910242 0.0519036606564101 0.276592997815047 GO:0005035 death receptor activity 1/79 13/18639 0.0769230769230769 18.1489776046738 0.0537367213611506 0.276592997815047 GO:0008253 5'-nucleotidase activity 1/79 13/18639 0.0769230769230769 18.1489776046738 0.0537367213611506 0.276592997815047 GO:0032396 inhibitory MHC class I receptor activity 1/79 13/18639 0.0769230769230769 18.1489776046738 0.0537367213611506 0.276592997815047 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/79 89/18639 0.0224719101123595 5.30194851372493 0.0548187591477282 0.276592997815047 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/79 89/18639 0.0224719101123595 5.30194851372493 0.0548187591477282 0.276592997815047 GO:0140793 histone H2AXY142 phosphatase activity 2/79 90/18639 0.0222222222222222 5.24303797468354 0.0559144590157015 0.276592997815047 GO:0008474 palmitoyl-(protein) hydrolase activity 1/79 14/18639 0.0714285714285714 16.8526220614828 0.0577501863569878 0.276592997815047 GO:0098599 palmitoyl hydrolase activity 1/79 14/18639 0.0714285714285714 16.8526220614828 0.0577501863569878 0.276592997815047 GO:0000774 adenyl-nucleotide exchange factor activity 1/79 15/18639 0.0666666666666667 15.7291139240506 0.061746843284655 0.28094813694518 GO:0008252 nucleotidase activity 1/79 15/18639 0.0666666666666667 15.7291139240506 0.061746843284655 0.28094813694518 GO:0140776 protein-containing complex destabilizing activity 1/79 15/18639 0.0666666666666667 15.7291139240506 0.061746843284655 0.28094813694518 GO:0004725 protein tyrosine phosphatase activity 2/79 98/18639 0.0204081632653061 4.81503487470938 0.0649507628281358 0.284815967090512 GO:0016722 oxidoreductase activity, acting on metal ions 1/79 16/18639 0.0625 14.7460443037975 0.065726761636272 0.284815967090512 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/79 16/18639 0.0625 14.7460443037975 0.065726761636272 0.284815967090512 GO:0017110 nucleoside diphosphate phosphatase activity 1/79 17/18639 0.0588235294117647 13.8786299329859 0.0696900106203632 0.291345042775351 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/79 17/18639 0.0588235294117647 13.8786299329859 0.0696900106203632 0.291345042775351 GO:0017075 syntaxin-1 binding 1/79 18/18639 0.0555555555555556 13.1075949367089 0.0736366591630008 0.291345042775351 GO:0032393 MHC class I receptor activity 1/79 18/18639 0.0555555555555556 13.1075949367089 0.0736366591630008 0.291345042775351 GO:0050811 GABA receptor binding 1/79 18/18639 0.0555555555555556 13.1075949367089 0.0736366591630008 0.291345042775351 GO:0070064 proline-rich region binding 1/79 18/18639 0.0555555555555556 13.1075949367089 0.0736366591630008 0.291345042775351 GO:0005520 insulin-like growth factor binding 1/79 19/18639 0.0526315789473684 12.4177215189873 0.0775667759089391 0.302510426044863 GO:0001972 retinoic acid binding 1/79 20/18639 0.05 11.796835443038 0.0814804292227518 0.304714481887825 GO:0031418 L-ascorbic acid binding 1/79 20/18639 0.05 11.796835443038 0.0814804292227518 0.304714481887825 GO:0042288 MHC class I protein binding 1/79 20/18639 0.05 11.796835443038 0.0814804292227518 0.304714481887825 GO:0070182 DNA polymerase binding 1/79 21/18639 0.0476190476190476 11.2350813743219 0.0853776871899575 0.311602489121187 GO:0017124 SH3 domain binding 2/79 115/18639 0.0173913043478261 4.1032471106219 0.0856050794288975 0.311602489121187 GO:0042277 peptide binding 3/79 249/18639 0.0120481927710843 2.84261095012963 0.0891306554585419 0.312405161663507 GO:0004407 histone deacetylase activity 1/79 22/18639 0.0454545454545455 10.7243958573073 0.0892586176181449 0.312405161663507 GO:0033558 protein lysine deacetylase activity 1/79 22/18639 0.0454545454545455 10.7243958573073 0.0892586176181449 0.312405161663507 GO:0004175 endopeptidase activity 4/79 405/18639 0.00987654320987654 2.33023909985935 0.0931162981075581 0.315158238540873 GO:0017134 fibroblast growth factor binding 1/79 23/18639 0.0434782608695652 10.2581177765548 0.0931232880380927 0.315158238540873 GO:0015295 solute:proton symporter activity 1/79 24/18639 0.0416666666666667 9.83069620253165 0.096971765704884 0.315158238540873 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/79 24/18639 0.0416666666666667 9.83069620253165 0.096971765704884 0.315158238540873 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/79 24/18639 0.0416666666666667 9.83069620253165 0.096971765704884 0.315158238540873 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/79 24/18639 0.0416666666666667 9.83069620253165 0.096971765704884 0.315158238540873 GO:0008157 protein phosphatase 1 binding 1/79 26/18639 0.0384615384615385 9.07448880233691 0.104620410427518 0.332108977287353 GO:0030247 polysaccharide binding 1/79 26/18639 0.0384615384615385 9.07448880233691 0.104620410427518 0.332108977287353 GO:0035255 ionotropic glutamate receptor binding 1/79 27/18639 0.037037037037037 8.73839662447257 0.108420710625026 0.336496909057693 GO:0016791 phosphatase activity 3/79 273/18639 0.010989010989011 2.59271108638197 0.109641728516168 0.336496909057693 GO:0045499 chemorepellent activity 1/79 28/18639 0.0357142857142857 8.42631103074141 0.112205084354911 0.336496909057693 GO:0046875 ephrin receptor binding 1/79 28/18639 0.0357142857142857 8.42631103074141 0.112205084354911 0.336496909057693 GO:0019838 growth factor binding 2/79 136/18639 0.0147058823529412 3.46965748324646 0.113398225763032 0.336496909057693 GO:0140789 histone phosphatase activity 2/79 136/18639 0.0147058823529412 3.46965748324646 0.113398225763032 0.336496909057693 GO:0005164 tumor necrosis factor receptor binding 1/79 31/18639 0.032258064516129 7.61086157615353 0.123463304326248 0.352744730387546 GO:0030296 protein tyrosine kinase activator activity 1/79 33/18639 0.0303030303030303 7.14959723820483 0.130890352855726 0.352744730387546 GO:0071889 14-3-3 protein binding 1/79 33/18639 0.0303030303030303 7.14959723820483 0.130890352855726 0.352744730387546 GO:0140311 protein sequestering activity 1/79 33/18639 0.0303030303030303 7.14959723820483 0.130890352855726 0.352744730387546 GO:0001664 G protein-coupled receptor binding 3/79 297/18639 0.0101010101010101 2.38319907940161 0.131796307664921 0.352744730387546 GO:0000510 H3-H4 histone complex chaperone activity 2/79 151/18639 0.0132450331125828 3.12498952133456 0.134478033660681 0.352744730387546 GO:0140584 chromatin extrusion motor activity 2/79 151/18639 0.0132450331125828 3.12498952133456 0.134478033660681 0.352744730387546 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/79 151/18639 0.0132450331125828 3.12498952133456 0.134478033660681 0.352744730387546 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/79 151/18639 0.0132450331125828 3.12498952133456 0.134478033660681 0.352744730387546 GO:0015035 protein-disulfide reductase activity 1/79 34/18639 0.0294117647058824 6.93931496649293 0.134580542156188 0.352744730387546 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/79 34/18639 0.0294117647058824 6.93931496649293 0.134580542156188 0.352744730387546 GO:0015616 DNA translocase activity 2/79 152/18639 0.0131578947368421 3.10443037974684 0.135913805864612 0.352744730387546 GO:0140674 ATP-dependent histone chaperone activity 2/79 152/18639 0.0131578947368421 3.10443037974684 0.135913805864612 0.352744730387546 GO:0061775 cohesin loader activity 2/79 153/18639 0.0130718954248366 3.08413998510797 0.137353066771311 0.352744730387546 GO:0005154 epidermal growth factor receptor binding 1/79 35/18639 0.0285714285714286 6.74104882459313 0.138255260628086 0.352744730387546 GO:0140658 ATP-dependent chromatin remodeler activity 2/79 158/18639 0.0126582278481013 2.98654061849063 0.144599814986793 0.357993071217596 GO:0019213 deacetylase activity 1/79 37/18639 0.027027027027027 6.37666780704755 0.145558540953126 0.357993071217596 GO:0003689 DNA clamp loader activity 2/79 160/18639 0.0125 2.94920886075949 0.147521064407117 0.357993071217596 GO:0005501 retinoid binding 1/79 38/18639 0.0263157894736842 6.20886075949367 0.149187230086806 0.357993071217596 GO:0019840 isoprenoid binding 1/79 38/18639 0.0263157894736842 6.20886075949367 0.149187230086806 0.357993071217596 GO:0140713 histone chaperone activity 2/79 164/18639 0.0121951219512195 2.87727693732634 0.153399936222186 0.357993071217596 GO:0030695 GTPase regulator activity 4/79 489/18639 0.0081799591002045 1.92995262871787 0.153498077325957 0.357993071217596 GO:0060589 nucleoside-triphosphatase regulator activity 4/79 490/18639 0.00816326530612245 1.92601394988375 0.154292575750687 0.357993071217596 GO:0015036 disulfide oxidoreductase activity 1/79 40/18639 0.025 5.89841772151899 0.156399022550076 0.357993071217596 GO:0061791 GTPase motor activity 1/79 40/18639 0.025 5.89841772151899 0.156399022550076 0.357993071217596 GO:0071949 FAD binding 1/79 40/18639 0.025 5.89841772151899 0.156399022550076 0.357993071217596 GO:1990606 membrane scission GTPase motor activity 1/79 40/18639 0.025 5.89841772151899 0.156399022550076 0.357993071217596 GO:0005201 extracellular matrix structural constituent 2/79 168/18639 0.0119047619047619 2.80877034358047 0.159324610381753 0.357993071217596 GO:0001727 lipid kinase activity 1/79 41/18639 0.024390243902439 5.75455387465267 0.159982251606398 0.357993071217596 GO:0042169 SH2 domain binding 1/79 41/18639 0.024390243902439 5.75455387465267 0.159982251606398 0.357993071217596 GO:0003735 structural constituent of ribosome 2/79 175/18639 0.0114285714285714 2.69641952983725 0.169793570060964 0.366813159062089 GO:0004721 phosphoprotein phosphatase activity 2/79 175/18639 0.0114285714285714 2.69641952983725 0.169793570060964 0.366813159062089 GO:0001223 transcription coactivator binding 1/79 44/18639 0.0227272727272727 5.36219792865363 0.170642019050862 0.366813159062089 GO:0016790 thiolester hydrolase activity 1/79 44/18639 0.0227272727272727 5.36219792865363 0.170642019050862 0.366813159062089 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/79 44/18639 0.0227272727272727 5.36219792865363 0.170642019050862 0.366813159062089 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/79 181/18639 0.0110497237569061 2.60703545702497 0.178858631838652 0.380404810040592 GO:0001784 phosphotyrosine residue binding 1/79 47/18639 0.0212765957446809 5.01992997576084 0.181168205602111 0.380404810040592 GO:0005504 fatty acid binding 1/79 47/18639 0.0212765957446809 5.01992997576084 0.181168205602111 0.380404810040592 GO:0140693 molecular condensate scaffold activity 1/79 48/18639 0.0208333333333333 4.91534810126582 0.18464753605378 0.380404810040592 GO:0015078 proton transmembrane transporter activity 2/79 185/18639 0.0108108108108108 2.55066712281902 0.184943874309611 0.380404810040592 GO:0001222 transcription corepressor binding 1/79 49/18639 0.0204081632653061 4.81503487470938 0.188112268701392 0.380404810040592 GO:0035254 glutamate receptor binding 1/79 49/18639 0.0204081632653061 4.81503487470938 0.188112268701392 0.380404810040592 GO:0060590 ATPase regulator activity 1/79 49/18639 0.0204081632653061 4.81503487470938 0.188112268701392 0.380404810040592 GO:0140597 protein carrier chaperone 2/79 188/18639 0.0106382978723404 2.50996498788042 0.189527798244484 0.380449183240766 GO:0032813 tumor necrosis factor receptor superfamily binding 1/79 50/18639 0.02 4.71873417721519 0.191562464009223 0.381726661857796 GO:0042578 phosphoric ester hydrolase activity 3/79 363/18639 0.00826446280991736 1.94989015587405 0.199459025604381 0.394581985434753 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/79 54/18639 0.0185185185185185 4.36919831223629 0.205219072497051 0.397339055260248 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/79 54/18639 0.0185185185185185 4.36919831223629 0.205219072497051 0.397339055260248 GO:0051287 NAD binding 1/79 54/18639 0.0185185185185185 4.36919831223629 0.205219072497051 0.397339055260248 GO:0036002 pre-mRNA binding 1/79 59/18639 0.0169491525423729 3.99892726882643 0.2219698965154 0.421238981425298 GO:0045309 protein phosphorylated amino acid binding 1/79 59/18639 0.0169491525423729 3.99892726882643 0.2219698965154 0.421238981425298 GO:0008094 ATP-dependent activity, acting on DNA 2/79 210/18639 0.00952380952380952 2.24701627486438 0.223558000495624 0.421238981425298 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/79 60/18639 0.0166666666666667 3.93227848101266 0.225277990066276 0.421238981425298 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/79 60/18639 0.0166666666666667 3.93227848101266 0.225277990066276 0.421238981425298 GO:0019905 syntaxin binding 1/79 61/18639 0.0163934426229508 3.86781489935671 0.228572195286405 0.424491219817609 GO:0160215 deacylase activity 1/79 65/18639 0.0153846153846154 3.62979552093476 0.24161128058848 0.445674862166588 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/79 67/18639 0.0149253731343284 3.52144341583223 0.248048978746129 0.451449141317955 GO:0050840 extracellular matrix binding 1/79 67/18639 0.0149253731343284 3.52144341583223 0.248048978746129 0.451449141317955 GO:0005125 cytokine activity 2/79 234/18639 0.00854700854700855 2.01655306718598 0.261180422457447 0.472200366429689 GO:0048029 monosaccharide binding 1/79 74/18639 0.0135135135135135 3.18833390352378 0.270158897505437 0.485219598809107 GO:0044183 protein folding chaperone 1/79 75/18639 0.0133333333333333 3.14582278481013 0.273264604324563 0.487589784186965 GO:0001618 virus receptor activity 1/79 81/18639 0.0123456790123457 2.91279887482419 0.291626699044456 0.511050861214445 GO:0030971 receptor tyrosine kinase binding 1/79 81/18639 0.0123456790123457 2.91279887482419 0.291626699044456 0.511050861214445 GO:0140272 exogenous protein binding 1/79 82/18639 0.0121951219512195 2.87727693732634 0.29464219051851 0.511050861214445 GO:0001540 amyloid-beta binding 1/79 83/18639 0.0120481927710843 2.84261095012963 0.297645007080941 0.511050861214445 GO:0005254 chloride channel activity 1/79 83/18639 0.0120481927710843 2.84261095012963 0.297645007080941 0.511050861214445 GO:0030165 PDZ domain binding 1/79 83/18639 0.0120481927710843 2.84261095012963 0.297645007080941 0.511050861214445 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/79 86/18639 0.0116279069767442 2.74345010303209 0.306577932180513 0.519849537175652 GO:0050660 flavin adenine dinucleotide binding 1/79 86/18639 0.0116279069767442 2.74345010303209 0.306577932180513 0.519849537175652 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/79 88/18639 0.0113636363636364 2.68109896432681 0.312470799551014 0.526571162206338 GO:0005096 GTPase activator activity 2/79 271/18639 0.00738007380073801 1.74123032369564 0.31922213480984 0.534571620388939 GO:0005126 cytokine receptor binding 2/79 275/18639 0.00727272727272727 1.71590333716916 0.325453335251377 0.534571620388939 GO:0051213 dioxygenase activity 1/79 93/18639 0.010752688172043 2.53695385871784 0.3269875176975 0.534571620388939 GO:0051219 phosphoprotein binding 1/79 93/18639 0.010752688172043 2.53695385871784 0.3269875176975 0.534571620388939 GO:0008017 microtubule binding 2/79 276/18639 0.0072463768115942 1.70968629609246 0.327009013204956 0.534571620388939 GO:0004867 serine-type endopeptidase inhibitor activity 1/79 95/18639 0.0105263157894737 2.48354430379747 0.332709093693851 0.538282699427589 GO:0030246 carbohydrate binding 2/79 280/18639 0.00714285714285714 1.68526220614828 0.333222623455174 0.538282699427589 GO:0004896 cytokine receptor activity 1/79 96/18639 0.0104166666666667 2.45767405063291 0.335551845074254 0.538681208722804 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/79 484/18639 0.00619834710743802 1.46241761690553 0.337415702167031 0.538681208722804 GO:0042626 ATPase-coupled transmembrane transporter activity 1/79 98/18639 0.0102040816326531 2.40751743735469 0.341201523911309 0.541558232719695 GO:0001216 DNA-binding transcription activator activity 3/79 491/18639 0.00610997963340122 1.44156848591095 0.345564577551843 0.545312888275452 GO:0005253 monoatomic anion channel activity 1/79 103/18639 0.00970873786407767 2.29064765884233 0.355119051277862 0.557169545970439 GO:0000149 SNARE binding 1/79 106/18639 0.00943396226415094 2.22581800812037 0.363329803297369 0.560390035594247 GO:0004497 monooxygenase activity 1/79 106/18639 0.00943396226415094 2.22581800812037 0.363329803297369 0.560390035594247 GO:0008013 beta-catenin binding 1/79 106/18639 0.00943396226415094 2.22581800812037 0.363329803297369 0.560390035594247 GO:0004222 metalloendopeptidase activity 1/79 110/18639 0.00909090909090909 2.14487917146145 0.374117107964721 0.5737863509796 GO:1902936 phosphatidylinositol bisphosphate binding 1/79 111/18639 0.00900900900900901 2.12555593568252 0.376785614007723 0.574650685050885 GO:0005200 structural constituent of cytoskeleton 1/79 112/18639 0.00892857142857143 2.10657775768535 0.379442886055078 0.575488377183535 GO:0001221 transcription coregulator binding 1/79 115/18639 0.00869565217391304 2.05162355531095 0.387347764162052 0.581744449741038 GO:0009055 electron transfer activity 1/79 116/18639 0.00862068965517241 2.03393714535137 0.389960565211026 0.581744449741038 GO:0015294 solute:monoatomic cation symporter activity 1/79 116/18639 0.00862068965517241 2.03393714535137 0.389960565211026 0.581744449741038 GO:1990782 protein tyrosine kinase binding 1/79 117/18639 0.00854700854700855 2.01655306718598 0.392562363804576 0.582443072383963 GO:0022853 active monoatomic ion transmembrane transporter activity 1/79 118/18639 0.00847457627118644 1.99946363441322 0.395153205682312 0.583117973790656 GO:0015108 chloride transmembrane transporter activity 1/79 121/18639 0.00826446280991736 1.94989015587405 0.402860445605952 0.591295170163575 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/79 122/18639 0.00819672131147541 1.93390744967836 0.40540791427412 0.591852195704999 GO:0003924 GTPase activity 2/79 331/18639 0.00604229607250755 1.42559944930973 0.410702504912061 0.596392467239322 GO:0045296 cadherin binding 2/79 334/18639 0.00598802395209581 1.41279466383688 0.415135176556196 0.597571753420276 GO:0042826 histone deacetylase binding 1/79 127/18639 0.0078740157480315 1.85776936110834 0.417985185098622 0.597571753420276 GO:0140097 catalytic activity, acting on DNA 2/79 336/18639 0.00595238095238095 1.40438517179024 0.418081336642025 0.597571753420276 GO:0035591 signaling adaptor activity 1/79 129/18639 0.00775193798449612 1.82896673535472 0.422942218257068 0.601370966584269 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/79 130/18639 0.00769230769230769 1.81489776046738 0.425405079670234 0.601738791450642 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/79 132/18639 0.00757575757575758 1.78739930955121 0.430299708955495 0.605524848169331 GO:0051087 protein-folding chaperone binding 1/79 134/18639 0.00746268656716418 1.76072170791612 0.435153167166921 0.609214434033689 GO:0002020 protease binding 1/79 136/18639 0.00735294117647059 1.73482874162323 0.439965796211178 0.61280950186557 GO:0030295 protein kinase activator activity 1/79 139/18639 0.00719424460431655 1.69738639468172 0.447108926118017 0.616468367829387 GO:0070851 growth factor receptor binding 1/79 139/18639 0.00719424460431655 1.69738639468172 0.447108926118017 0.616468367829387 GO:0019903 protein phosphatase binding 1/79 144/18639 0.00694444444444444 1.63844936708861 0.458814761226666 0.626282149074399 GO:0019955 cytokine binding 1/79 144/18639 0.00694444444444444 1.63844936708861 0.458814761226666 0.626282149074399 GO:0015293 symporter activity 1/79 146/18639 0.00684931506849315 1.61600485521068 0.463428275726833 0.629228161998511 GO:0046982 protein heterodimerization activity 2/79 369/18639 0.00542005420054201 1.27878974992282 0.465582742577653 0.629228161998511 GO:0019209 kinase activator activity 1/79 148/18639 0.00675675675675676 1.59416695176189 0.46800295442832 0.629283803824616 GO:0008509 monoatomic anion transmembrane transporter activity 1/79 149/18639 0.00671140939597315 1.58346784470308 0.470275831319789 0.629283803824616 GO:0019842 vitamin binding 1/79 150/18639 0.00666666666666667 1.57291139240506 0.472539120088082 0.629283803824616 GO:0003774 cytoskeletal motor activity 1/79 153/18639 0.0065359477124183 1.54206999255398 0.479271856144492 0.635151537511876 GO:0015631 tubulin binding 2/79 385/18639 0.00519480519480519 1.22564524083511 0.487801032335401 0.643331796268427 GO:0004866 endopeptidase inhibitor activity 1/79 161/18639 0.0062111801242236 1.46544539665068 0.496813784181565 0.652068091738304 GO:0015103 inorganic anion transmembrane transporter activity 1/79 165/18639 0.00606060606060606 1.42991944764097 0.505364643373045 0.659723795566813 GO:0015399 primary active transmembrane transporter activity 1/79 166/18639 0.00602409638554217 1.42130547506482 0.507479842743703 0.659723795566813 GO:0030414 peptidase inhibitor activity 1/79 169/18639 0.00591715976331361 1.39607520035952 0.513772002584407 0.664738183438593 GO:0008201 heparin binding 1/79 172/18639 0.00581395348837209 1.37172505151604 0.519984782022062 0.669603044773694 GO:0043021 ribonucleoprotein complex binding 1/79 177/18639 0.00564971751412429 1.33297575627548 0.530165693550191 0.676765501309702 GO:0016887 ATP hydrolysis activity 2/79 417/18639 0.00479616306954436 1.13159092978782 0.530504825202477 0.676765501309702 GO:0008237 metallopeptidase activity 1/79 184/18639 0.00543478260869565 1.28226472206935 0.544061689563331 0.686920105031795 GO:0061135 endopeptidase regulator activity 1/79 184/18639 0.00543478260869565 1.28226472206935 0.544061689563331 0.686920105031795 GO:1901981 phosphatidylinositol phosphate binding 1/79 185/18639 0.00540540540540541 1.27533356140951 0.546013416820145 0.686920105031795 GO:0019902 phosphatase binding 1/79 190/18639 0.00526315789473684 1.24177215189873 0.555648998195594 0.695835672052281 GO:0003779 actin binding 2/79 443/18639 0.00451467268623025 1.06517701517273 0.563417366564896 0.702342196676789 GO:0022804 active transmembrane transporter activity 2/79 457/18639 0.00437636761487965 1.03254577181952 0.580457590459966 0.720295100888958 GO:0061134 peptidase regulator activity 1/79 226/18639 0.00442477876106195 1.04396773832194 0.619311270319273 0.722499194424976 GO:0000287 magnesium ion binding 1/79 230/18639 0.00434782608695652 1.02581177765548 0.625803168991403 0.722499194424976 GO:0005539 glycosaminoglycan binding 1/79 242/18639 0.00413223140495868 0.974945077937023 0.644630133872811 0.722499194424976 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/79 243/18639 0.00411522633744856 0.97093295827473 0.646156155475467 0.722499194424976 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0004711 ribosomal protein S6 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0035175 histone H3S10 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0035979 histone H2AXS139 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0044022 histone H3S28 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0044023 histone H4S1 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0044024 histone H2AS1 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0044025 histone H2BS14 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0072354 histone H3T3 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0072371 histone H2AS121 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0140823 histone H2BS36 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0140855 histone H3S57 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0140995 histone H2A kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0140997 histone H4 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0140998 histone H2B kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:1990244 histone H2AT120 kinase activity 1/79 245/18639 0.00408163265306122 0.963006974941875 0.649188814531708 0.722499194424976 GO:0004677 DNA-dependent protein kinase activity 1/79 246/18639 0.0040650406504065 0.959092312442112 0.650695506042636 0.722499194424976 GO:0140857 histone H3T45 kinase activity 1/79 246/18639 0.0040650406504065 0.959092312442112 0.650695506042636 0.722499194424976 GO:0033218 amide binding 1/79 247/18639 0.00404858299595142 0.955209347614411 0.652195808060938 0.722499194424976 GO:0035402 histone H3T11 kinase activity 1/79 247/18639 0.00404858299595142 0.955209347614411 0.652195808060938 0.722499194424976 GO:0035403 histone H3T6 kinase activity 1/79 247/18639 0.00404858299595142 0.955209347614411 0.652195808060938 0.722499194424976 GO:0004679 AMP-activated protein kinase activity 1/79 248/18639 0.00403225806451613 0.951357697019191 0.653689747336883 0.722499194424976 GO:0019887 protein kinase regulator activity 1/79 255/18639 0.00392156862745098 0.92524199553239 0.663971389403959 0.730903989142261 GO:0003730 mRNA 3'-UTR binding 1/79 262/18639 0.00381679389312977 0.900521789544883 0.673951529074807 0.73891071260009 GO:1901681 sulfur compound binding 1/79 275/18639 0.00363636363636364 0.85795166858458 0.691715770373314 0.755353621247659 GO:0031267 small GTPase binding 1/79 283/18639 0.00353356890459364 0.833698617882542 0.702169005438845 0.760169143675975 GO:0035091 phosphatidylinositol binding 1/79 284/18639 0.00352112676056338 0.830763059368872 0.703450801503909 0.760169143675975 GO:0015291 secondary active transmembrane transporter activity 1/79 287/18639 0.00348432055749129 0.822079124950382 0.707263598878014 0.760169143675975 GO:0019207 kinase regulator activity 1/79 287/18639 0.00348432055749129 0.822079124950382 0.707263598878014 0.760169143675975 GO:0031625 ubiquitin protein ligase binding 1/79 302/18639 0.0033112582781457 0.781247380333641 0.725613470874499 0.776833245289169 GO:0051020 GTPase binding 1/79 315/18639 0.00317460317460317 0.749005424954792 0.740594774705371 0.789774896463149 GO:0044389 ubiquitin-like protein ligase binding 1/79 322/18639 0.0031055900621118 0.73272269832534 0.748324084803184 0.7949123546742 GO:0141003 histone H2AX kinase activity 1/79 354/18639 0.00282485875706215 0.666487878137739 0.780859641267365 0.823605391898823 GO:0140996 histone H3 kinase activity 1/79 357/18639 0.00280112044817927 0.660887139665993 0.783687916610962 0.823605391898823 GO:0035173 histone kinase activity 1/79 360/18639 0.00277777777777778 0.655379746835443 0.78648014574998 0.823605391898823 GO:0106310 protein serine kinase activity 1/79 361/18639 0.00277008310249307 0.653564290473018 0.787402957090084 0.823605391898823 GO:0005525 GTP binding 1/79 378/18639 0.00264550264550265 0.624171187462327 0.802501560814535 0.836194374436519 GO:0019001 guanyl nucleotide binding 1/79 400/18639 0.0025 0.589841772151899 0.820478730076262 0.848449595874317 GO:0032561 guanyl ribonucleotide binding 1/79 400/18639 0.0025 0.589841772151899 0.820478730076262 0.848449595874317 GO:0004857 enzyme inhibitor activity 1/79 416/18639 0.00240384615384615 0.567155550146057 0.832528616471211 0.856663082601329 GO:0004984 olfactory receptor activity 1/79 419/18639 0.00238663484486874 0.563094770550739 0.834697362534628 0.856663082601329 GO:0004674 protein serine/threonine kinase activity 1/79 433/18639 0.0023094688221709 0.544888473119537 0.844457082028208 0.863433645669291 GO:0005216 monoatomic ion channel activity 1/79 448/18639 0.00223214285714286 0.526644439421338 0.85428298519354 0.867628308740511 GO:0004842 ubiquitin-protein transferase activity 1/79 449/18639 0.0022271714922049 0.525471511939331 0.854915806048342 0.867628308740511 GO:0019787 ubiquitin-like protein transferase activity 1/79 479/18639 0.00208768267223382 0.492560978832483 0.872688775715518 0.882301877969844 GO:0140297 DNA-binding transcription factor binding 1/79 488/18639 0.00204918032786885 0.483476862419589 0.877588463342006 0.882301877969844 GO:0016755 aminoacyltransferase activity 1/79 496/18639 0.00201612903225806 0.475678848509596 0.8817871441545 0.882301877969844 GO:0005543 phospholipid binding 1/79 497/18639 0.00201207243460765 0.474721748210784 0.882301877969844 0.882301877969844