ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030695 GTPase regulator activity 42/534 489/18639 0.0858895705521472 2.99793203281175 2.47333416087862e-10 1.18542278414354e-07 GO:0060589 nucleoside-triphosphatase regulator activity 42/534 490/18639 0.0857142857142857 2.99181380417335 2.63427285365232e-10 1.18542278414354e-07 GO:0005096 GTPase activator activity 28/534 271/18639 0.103321033210332 3.60636842323479 4.95099655251151e-09 1.48529896575345e-06 GO:0035091 phosphatidylinositol binding 27/534 284/18639 0.0950704225352113 3.31838502927678 5.41097654785956e-08 1.2174697232684e-05 GO:0005543 phospholipid binding 32/534 497/18639 0.0643863179074447 2.24737187167952 1.86479345015658e-05 0.00335662821028185 GO:1901981 phosphatidylinositol phosphate binding 16/534 185/18639 0.0864864864864865 3.01876708168843 8.81743466412898e-05 0.0119845133996854 GO:0038024 cargo receptor activity 9/534 65/18639 0.138461538461538 4.83292999135696 9.32128819975533e-05 0.0119845133996854 GO:0034987 immunoglobulin receptor binding 5/534 19/18639 0.263157894736842 9.18539325842697 0.000157847976926725 0.0177578974042566 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 5/534 21/18639 0.238095238095238 8.31059390048154 0.000263442659657859 0.0229949490402311 GO:0001786 phosphatidylserine binding 8/534 59/18639 0.135593220338983 4.73281279756237 0.000264172621775036 0.0229949490402311 GO:0005516 calmodulin binding 16/534 207/18639 0.0772946859903382 2.69793193290995 0.000321856824279811 0.0229949490402311 GO:0008093 cytoskeletal anchor activity 5/534 22/18639 0.227272727272727 7.93283963227783 0.00033294723607702 0.0229949490402311 GO:0019905 syntaxin binding 8/534 61/18639 0.131147540983607 4.57763860747836 0.000333712608223717 0.0229949490402311 GO:0005085 guanyl-nucleotide exchange factor activity 17/534 230/18639 0.0739130434782609 2.57989741084514 0.000357699207292484 0.0229949490402311 GO:0031267 small GTPase binding 19/534 283/18639 0.0671378091872792 2.34341128359868 0.000550429573923996 0.0330257744354398 GO:0051020 GTPase binding 20/534 315/18639 0.0634920634920635 2.21615837346174 0.000802285075226473 0.0451285354814891 GO:0000149 SNARE binding 10/534 106/18639 0.0943396226415094 3.29287682849269 0.000930985127947037 0.0492874479501372 GO:0072341 modified amino acid binding 9/534 91/18639 0.0989010989010989 3.45209285096926 0.001185830682174 0.0592915341087 GO:0043178 alcohol binding 9/534 92/18639 0.0978260869565217 3.41457010258915 0.00128179893284019 0.0607167915555881 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 5/534 30/18639 0.166666666666667 5.81741573033708 0.00149171610046783 0.0671272245210524 GO:0004715 non-membrane spanning protein tyrosine kinase activity 6/534 45/18639 0.133333333333333 4.65393258426966 0.00169544422456913 0.070956053105227 GO:0001221 transcription coregulator binding 10/534 115/18639 0.0869565217391304 3.03517342452369 0.00173448129812777 0.070956053105227 GO:0042626 ATPase-coupled transmembrane transporter activity 9/534 98/18639 0.0918367346938776 3.20551479018574 0.00199726850740249 0.0781539850722712 GO:0140359 ABC-type transporter activity 6/534 47/18639 0.127659574468085 4.45589289983266 0.00213002398976911 0.0798758996163417 GO:0004713 protein tyrosine kinase activity 11/534 140/18639 0.0785714285714286 2.74249598715891 0.0023495753037868 0.0835692133723733 GO:0031720 haptoglobin binding 3/534 10/18639 0.3 10.4713483146067 0.00241422171964634 0.0835692133723733 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 7/534 67/18639 0.104477611940299 3.64673821901727 0.00300033890738083 0.100011296912694 GO:0032934 sterol binding 7/534 68/18639 0.102941176470588 3.59310971579643 0.00326392404554447 0.104911844321072 GO:0043274 phospholipase binding 4/534 23/18639 0.173913043478261 6.07034684904739 0.00382512974033444 0.115952661833994 GO:0005496 steroid binding 9/534 108/18639 0.0833333333333333 2.90870786516854 0.00386508872779982 0.115952661833994 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 3/534 12/18639 0.25 8.72612359550562 0.0042409200863044 0.121350950496008 GO:0015485 cholesterol binding 6/534 54/18639 0.111111111111111 3.87827715355805 0.00433078512418874 0.121350950496008 GO:0003823 antigen binding 12/534 174/18639 0.0689655172413793 2.407206509105 0.0044495348515203 0.121350950496008 GO:0003707 nuclear steroid receptor activity 4/534 25/18639 0.16 5.5847191011236 0.00522324638819393 0.129042867543224 GO:0048029 monosaccharide binding 7/534 74/18639 0.0945945945945946 3.30177649559672 0.00523413231159525 0.129042867543224 GO:0005319 lipid transporter activity 12/534 178/18639 0.0674157303370786 2.3531119808105 0.00532541816450674 0.129042867543224 GO:0017154 semaphorin receptor activity 3/534 13/18639 0.230769230769231 8.05488331892826 0.00539690886771144 0.129042867543224 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 5/534 40/18639 0.125 4.36306179775281 0.00544847662960279 0.129042867543224 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/534 41/18639 0.121951219512195 4.2566456563442 0.00606205118662768 0.139893488922177 GO:0004879 nuclear receptor activity 6/534 59/18639 0.101694915254237 3.54960959817178 0.00670373282637174 0.140737603842521 GO:0005344 oxygen carrier activity 3/534 14/18639 0.214285714285714 7.47953451043339 0.0067241299613649 0.140737603842521 GO:0005545 1-phosphatidylinositol binding 3/534 14/18639 0.214285714285714 7.47953451043339 0.0067241299613649 0.140737603842521 GO:0019763 immunoglobulin receptor activity 3/534 14/18639 0.214285714285714 7.47953451043339 0.0067241299613649 0.140737603842521 GO:0098531 ligand-modulated transcription factor activity 6/534 60/18639 0.1 3.49044943820225 0.00727287403745612 0.14876333258433 GO:0001223 transcription coactivator binding 5/534 44/18639 0.113636363636364 3.96641981613892 0.00819178929037876 0.160990608543184 GO:0034483 heparan sulfate sulfotransferase activity 3/534 15/18639 0.2 6.98089887640449 0.00822840888109609 0.160990608543184 GO:0099604 ligand-gated calcium channel activity 4/534 29/18639 0.137931034482759 4.81441301821 0.00896276190555203 0.17162735563823 GO:0001540 amyloid-beta binding 7/534 83/18639 0.0843373493975904 2.94375253824286 0.0097046188475713 0.178449768844812 GO:0015085 calcium ion transmembrane transporter activity 10/534 147/18639 0.0680272108843537 2.37445540013758 0.00987274237847049 0.178449768844812 GO:0016769 transferase activity, transferring nitrogenous groups 4/534 30/18639 0.133333333333333 4.65393258426966 0.0101121535678727 0.178449768844812 GO:0031624 ubiquitin conjugating enzyme binding 4/534 30/18639 0.133333333333333 4.65393258426966 0.0101121535678727 0.178449768844812 GO:0120013 lipid transfer activity 6/534 65/18639 0.0923076923076923 3.22195332757131 0.0106516419428003 0.184355341317698 GO:0061659 ubiquitin-like protein ligase activity 19/534 372/18639 0.0510752688172043 1.7827564334904 0.0112518230372377 0.189214707970042 GO:0005164 tumor necrosis factor receptor binding 4/534 31/18639 0.129032258064516 4.50380572671258 0.0113528824782025 0.189214707970042 GO:0015278 intracellularly gated calcium channel activity 3/534 17/18639 0.176470588235294 6.15961665565102 0.0117867867750247 0.192874692682222 GO:0008081 phosphoric diester hydrolase activity 7/534 87/18639 0.0804597701149425 2.80840759395583 0.0123977290412054 0.199249216733658 GO:0120015 sterol transfer activity 4/534 32/18639 0.125 4.36306179775281 0.0126874214139698 0.200327706536366 GO:0005262 calcium channel activity 9/534 131/18639 0.0687022900763359 2.39801869800154 0.013182742662004 0.201827804744062 GO:0017075 syntaxin-1 binding 3/534 18/18639 0.166666666666667 5.81741573033708 0.0138480653677224 0.201827804744062 GO:0034185 apolipoprotein binding 3/534 18/18639 0.166666666666667 5.81741573033708 0.0138480653677224 0.201827804744062 GO:0070064 proline-rich region binding 3/534 18/18639 0.166666666666667 5.81741573033708 0.0138480653677224 0.201827804744062 GO:0032813 tumor necrosis factor receptor superfamily binding 5/534 50/18639 0.1 3.49044943820225 0.013903693215702 0.201827804744062 GO:0140375 immune receptor activity 10/534 156/18639 0.0641025641025641 2.23746758859118 0.0145474893612717 0.207821276589596 GO:0005272 sodium channel activity 5/534 51/18639 0.0980392156862745 3.42200925313946 0.0150622319887753 0.211812637342153 GO:0044325 transmembrane transporter binding 9/534 136/18639 0.0661764705882353 2.30985624586913 0.0164921285055428 0.226054933569083 GO:0016755 aminoacyltransferase activity 23/534 496/18639 0.0463709677419355 1.61855518303733 0.0165773617950661 0.226054933569083 GO:0051018 protein kinase A binding 5/534 53/18639 0.0943396226415094 3.29287682849269 0.0175690757727749 0.236002510380559 GO:0001614 purinergic nucleotide receptor activity 3/534 20/18639 0.15 5.23567415730337 0.0185469209370213 0.241916360048104 GO:0016502 nucleotide receptor activity 3/534 20/18639 0.15 5.23567415730337 0.0185469209370213 0.241916360048104 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/534 36/18639 0.111111111111111 3.87827715355805 0.0190070723120527 0.244376644012107 GO:0019787 ubiquitin-like protein transferase activity 22/534 479/18639 0.0459290187891441 1.60312917829748 0.0207378755548687 0.261380600443506 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/534 21/18639 0.142857142857143 4.98635634028892 0.0211872376927543 0.261380600443506 GO:0019902 phosphatase binding 11/534 190/18639 0.0578947368421053 2.02078651685393 0.0213002123050809 0.261380600443506 GO:0015399 primary active transmembrane transporter activity 10/534 166/18639 0.0602409638554217 2.10268038445918 0.0214912938142438 0.261380600443506 GO:0000146 microfilament motor activity 4/534 38/18639 0.105263157894737 3.67415730337079 0.0227812793779813 0.273375352535775 GO:0061630 ubiquitin protein ligase activity 17/534 353/18639 0.0481586402266289 1.68095298723621 0.0263887588531124 0.30451321990749 GO:0045309 protein phosphorylated amino acid binding 5/534 59/18639 0.0847457627118644 2.95800799847648 0.0266936074992412 0.30451321990749 GO:0005158 insulin receptor binding 3/534 23/18639 0.130434782608696 4.55276013678554 0.0270518202131575 0.30451321990749 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/534 23/18639 0.130434782608696 4.55276013678554 0.0270518202131575 0.30451321990749 GO:0042277 peptide binding 13/534 249/18639 0.0522088353413655 1.82232299986463 0.0277731513683511 0.30451321990749 GO:0140996 histone H3 kinase activity 17/534 357/18639 0.0476190476190476 1.66211878009631 0.0289647543657019 0.30451321990749 GO:0042169 SH2 domain binding 4/534 41/18639 0.0975609756097561 3.40531652507536 0.0292417465209567 0.30451321990749 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/534 24/18639 0.125 4.36306179775281 0.0302752739027717 0.30451321990749 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/534 24/18639 0.125 4.36306179775281 0.0302752739027717 0.30451321990749 GO:0004622 lysophospholipase activity 3/534 24/18639 0.125 4.36306179775281 0.0302752739027717 0.30451321990749 GO:0030552 cAMP binding 3/534 24/18639 0.125 4.36306179775281 0.0302752739027717 0.30451321990749 GO:0035173 histone kinase activity 17/534 360/18639 0.0472222222222222 1.64826779026217 0.0310165202293529 0.30451321990749 GO:0003779 actin binding 20/534 443/18639 0.0451467268623025 1.57582367413194 0.0310609406224365 0.30451321990749 GO:0048487 beta-tubulin binding 4/534 42/18639 0.0952380952380952 3.32423756019262 0.0316121810062757 0.30451321990749 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/534 10/18639 0.2 6.98089887640449 0.0316570973947928 0.30451321990749 GO:0005031 tumor necrosis factor receptor activity 2/534 10/18639 0.2 6.98089887640449 0.0316570973947928 0.30451321990749 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/534 10/18639 0.2 6.98089887640449 0.0316570973947928 0.30451321990749 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/534 10/18639 0.2 6.98089887640449 0.0316570973947928 0.30451321990749 GO:0030165 PDZ domain binding 6/534 83/18639 0.072289156626506 2.52321646135102 0.0318047140792268 0.30451321990749 GO:0008483 transaminase activity 3/534 25/18639 0.12 4.1885393258427 0.0336914594729414 0.319182247638392 GO:0004842 ubiquitin-protein transferase activity 20/534 449/18639 0.044543429844098 1.55476589674933 0.0350073338895823 0.322386239373921 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/534 86/18639 0.0697674418604651 2.43519728246668 0.0369237873280879 0.322386239373921 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/534 26/18639 0.115384615384615 4.02744165946413 0.0372987772273068 0.322386239373921 GO:0034237 protein kinase A regulatory subunit binding 3/534 26/18639 0.115384615384615 4.02744165946413 0.0372987772273068 0.322386239373921 GO:0050750 low-density lipoprotein particle receptor binding 3/534 26/18639 0.115384615384615 4.02744165946413 0.0372987772273068 0.322386239373921 GO:0005536 D-glucose binding 2/534 11/18639 0.181818181818182 6.34627170582227 0.0379699348595952 0.322386239373921 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/534 11/18639 0.181818181818182 6.34627170582227 0.0379699348595952 0.322386239373921 GO:0019864 IgG binding 2/534 11/18639 0.181818181818182 6.34627170582227 0.0379699348595952 0.322386239373921 GO:0034056 estrogen response element binding 2/534 11/18639 0.181818181818182 6.34627170582227 0.0379699348595952 0.322386239373921 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/534 11/18639 0.181818181818182 6.34627170582227 0.0379699348595952 0.322386239373921 GO:0140537 transcription regulator activator activity 2/534 11/18639 0.181818181818182 6.34627170582227 0.0379699348595952 0.322386239373921 GO:0042605 peptide antigen binding 4/534 45/18639 0.0888888888888889 3.10262172284644 0.0393825790447698 0.330229427839534 GO:1902936 phosphatidylinositol bisphosphate binding 7/534 111/18639 0.0630630630630631 2.20118433039781 0.0404967316844701 0.330229427839534 GO:0005044 scavenger receptor activity 3/534 27/18639 0.111111111111111 3.87827715355805 0.0410952176866975 0.330229427839534 GO:0023026 MHC class II protein complex binding 3/534 27/18639 0.111111111111111 3.87827715355805 0.0410952176866975 0.330229427839534 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 3/534 27/18639 0.111111111111111 3.87827715355805 0.0410952176866975 0.330229427839534 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/534 27/18639 0.111111111111111 3.87827715355805 0.0410952176866975 0.330229427839534 GO:0005178 integrin binding 9/534 161/18639 0.0559006211180124 1.95118291576523 0.0425159906659683 0.335562092414194 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 16/534 349/18639 0.0458452722063037 1.60020604616722 0.0446040157168463 0.335562092414194 GO:0004300 enoyl-CoA hydratase activity 2/534 12/18639 0.166666666666667 5.81741573033708 0.0447157378142534 0.335562092414194 GO:0005078 MAP-kinase scaffold activity 2/534 12/18639 0.166666666666667 5.81741573033708 0.0447157378142534 0.335562092414194 GO:0070679 inositol 1,4,5 trisphosphate binding 2/534 12/18639 0.166666666666667 5.81741573033708 0.0447157378142534 0.335562092414194 GO:0050698 proteoglycan sulfotransferase activity 3/534 28/18639 0.107142857142857 3.73976725521669 0.0450783960201354 0.335562092414194 GO:0051959 dynein light intermediate chain binding 3/534 28/18639 0.107142857142857 3.73976725521669 0.0450783960201354 0.335562092414194 GO:0001784 phosphotyrosine residue binding 4/534 47/18639 0.0851063829787234 2.9705952665551 0.0451144590912417 0.335562092414194 GO:0043495 protein-membrane adaptor activity 4/534 47/18639 0.0851063829787234 2.9705952665551 0.0451144590912417 0.335562092414194 GO:0030295 protein kinase activator activity 8/534 139/18639 0.0575539568345324 2.0088917629941 0.0468737554437504 0.341190786192984 GO:0017124 SH3 domain binding 7/534 115/18639 0.0608695652173913 2.12462139716659 0.0474962424258091 0.341190786192984 GO:0035401 histone H3Y41 kinase activity 7/534 115/18639 0.0608695652173913 2.12462139716659 0.0474962424258091 0.341190786192984 GO:0140801 histone H2AXY142 kinase activity 7/534 115/18639 0.0608695652173913 2.12462139716659 0.0474962424258091 0.341190786192984 GO:0032266 phosphatidylinositol-3-phosphate binding 4/534 48/18639 0.0833333333333333 2.90870786516854 0.0481458109405656 0.341190786192984 GO:0140693 molecular condensate scaffold activity 4/534 48/18639 0.0833333333333333 2.90870786516854 0.0481458109405656 0.341190786192984 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/534 29/18639 0.103448275862069 3.6108097636575 0.049245584571818 0.345687702974454 GO:0141003 histone H2AX kinase activity 16/534 354/18639 0.0451977401129944 1.57760426585412 0.0495485707596717 0.345687702974454 GO:0097110 scaffold protein binding 5/534 70/18639 0.0714285714285714 2.49317817014446 0.0501835905750894 0.347424857827542 GO:0005035 death receptor activity 2/534 13/18639 0.153846153846154 5.36992221261884 0.0518646158045338 0.348344434508063 GO:0008035 high-density lipoprotein particle binding 2/534 13/18639 0.153846153846154 5.36992221261884 0.0518646158045338 0.348344434508063 GO:0043560 insulin receptor substrate binding 2/534 13/18639 0.153846153846154 5.36992221261884 0.0518646158045338 0.348344434508063 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/534 13/18639 0.153846153846154 5.36992221261884 0.0518646158045338 0.348344434508063 GO:0001965 G-protein alpha-subunit binding 3/534 30/18639 0.1 3.49044943820225 0.0535937435722564 0.354664479522285 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/534 30/18639 0.1 3.49044943820225 0.0535937435722564 0.354664479522285 GO:0019955 cytokine binding 8/534 144/18639 0.0555555555555556 1.93913857677903 0.0555321261664441 0.364809587954742 GO:0008194 UDP-glycosyltransferase activity 8/534 145/18639 0.0551724137931034 1.925765207284 0.0573780890901993 0.368615359314177 GO:0016830 carbon-carbon lyase activity 4/534 51/18639 0.0784313725490196 2.73760740251157 0.0578974241545498 0.368615359314177 GO:0070273 phosphatidylinositol-4-phosphate binding 3/534 31/18639 0.0967741935483871 3.37785429503443 0.0581195501180479 0.368615359314177 GO:0070325 lipoprotein particle receptor binding 3/534 31/18639 0.0967741935483871 3.37785429503443 0.0581195501180479 0.368615359314177 GO:0043539 protein serine/threonine kinase activator activity 5/534 73/18639 0.0684931506849315 2.39071879328921 0.0581778396021101 0.368615359314177 GO:0008191 metalloendopeptidase inhibitor activity 2/534 14/18639 0.142857142857143 4.98635634028892 0.0593880301117286 0.368615359314177 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/534 14/18639 0.142857142857143 4.98635634028892 0.0593880301117286 0.368615359314177 GO:0061665 SUMO ligase activity 2/534 14/18639 0.142857142857143 4.98635634028892 0.0593880301117286 0.368615359314177 GO:0030246 carbohydrate binding 13/534 280/18639 0.0464285714285714 1.6205658105939 0.0606157934802403 0.373659000905591 GO:0005080 protein kinase C binding 4/534 52/18639 0.0769230769230769 2.68496110630942 0.061365243447147 0.374007943169854 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/534 122/18639 0.0573770491803279 2.00271689077178 0.061503528432376 0.374007943169854 GO:0071813 lipoprotein particle binding 3/534 32/18639 0.09375 3.27229634831461 0.0628194255012283 0.376374680513142 GO:0071814 protein-lipid complex binding 3/534 32/18639 0.09375 3.27229634831461 0.0628194255012283 0.376374680513142 GO:0019209 kinase activator activity 8/534 148/18639 0.0540540540540541 1.88672942605527 0.0631473075083161 0.376374680513142 GO:0008146 sulfotransferase activity 4/534 53/18639 0.0754716981132075 2.63430146279415 0.0649404408083203 0.384515767944002 GO:0004559 alpha-mannosidase activity 2/534 15/18639 0.133333333333333 4.65393258426966 0.0672587410702874 0.385559662186361 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/534 15/18639 0.133333333333333 4.65393258426966 0.0672587410702874 0.385559662186361 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/534 15/18639 0.133333333333333 4.65393258426966 0.0672587410702874 0.385559662186361 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/534 15/18639 0.133333333333333 4.65393258426966 0.0672587410702874 0.385559662186361 GO:0017081 chloride channel regulator activity 2/534 15/18639 0.133333333333333 4.65393258426966 0.0672587410702874 0.385559662186361 GO:0008376 acetylgalactosaminyltransferase activity 3/534 34/18639 0.0882352941176471 3.07980832782551 0.0727259419652651 0.399445185630012 GO:0015020 glucuronosyltransferase activity 3/534 34/18639 0.0882352941176471 3.07980832782551 0.0727259419652651 0.399445185630012 GO:0016831 carboxy-lyase activity 3/534 34/18639 0.0882352941176471 3.07980832782551 0.0727259419652651 0.399445185630012 GO:0019825 oxygen binding 3/534 34/18639 0.0882352941176471 3.07980832782551 0.0727259419652651 0.399445185630012 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/534 34/18639 0.0882352941176471 3.07980832782551 0.0727259419652651 0.399445185630012 GO:0042826 histone deacetylase binding 7/534 127/18639 0.0551181102362205 1.92386976908785 0.0729039022350661 0.399445185630012 GO:0004674 protein serine/threonine kinase activity 18/534 433/18639 0.0415704387990762 1.45099514752056 0.074442060665625 0.399445185630012 GO:0022836 gated channel activity 14/534 318/18639 0.0440251572327044 1.53667585329659 0.0748263120819455 0.399445185630012 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/534 16/18639 0.125 4.36306179775281 0.075450757285669 0.399445185630012 GO:0015923 mannosidase activity 2/534 16/18639 0.125 4.36306179775281 0.075450757285669 0.399445185630012 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/534 16/18639 0.125 4.36306179775281 0.075450757285669 0.399445185630012 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/534 16/18639 0.125 4.36306179775281 0.075450757285669 0.399445185630012 GO:0140328 floppase activity 2/534 16/18639 0.125 4.36306179775281 0.075450757285669 0.399445185630012 GO:0035591 signaling adaptor activity 7/534 129/18639 0.0542635658914729 1.89404233080742 0.0777914475994153 0.407743801710663 GO:0005154 epidermal growth factor receptor binding 3/534 35/18639 0.0857142857142857 2.99181380417335 0.0779243709935933 0.407743801710663 GO:0051015 actin filament binding 10/534 209/18639 0.0478468899521531 1.67007150153218 0.0789353320068111 0.410646235873584 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/534 130/18639 0.0538461538461538 1.87947277441659 0.0803052697399864 0.415372084861999 GO:0044389 ubiquitin-like protein ligase binding 14/534 322/18639 0.0434782608695652 1.51758671226185 0.0809167069796638 0.416143064466842 GO:0004033 aldo-keto reductase (NADPH) activity 3/534 36/18639 0.0833333333333333 2.90870786516854 0.0832804890555515 0.420715788477635 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/534 36/18639 0.0833333333333333 2.90870786516854 0.0832804890555515 0.420715788477635 GO:0030169 low-density lipoprotein particle binding 2/534 17/18639 0.117647058823529 4.10641110376735 0.083939286687088 0.420715788477635 GO:0045236 CXCR chemokine receptor binding 2/534 17/18639 0.117647058823529 4.10641110376735 0.083939286687088 0.420715788477635 GO:0008013 beta-catenin binding 6/534 106/18639 0.0566037735849057 1.97572609709561 0.0841431576955271 0.420715788477635 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/534 132/18639 0.053030303030303 1.85099591419816 0.0854726050659138 0.425001903642665 GO:0015276 ligand-gated monoatomic ion channel activity 9/534 186/18639 0.0483870967741935 1.68892714751722 0.0875983874758105 0.430097443943535 GO:0070888 E-box binding 4/534 59/18639 0.0677966101694915 2.36640639878118 0.088586785495805 0.430097443943535 GO:0023023 MHC protein complex binding 3/534 37/18639 0.0810810810810811 2.8300941390829 0.088789795843776 0.430097443943535 GO:0030551 cyclic nucleotide binding 3/534 37/18639 0.0810810810810811 2.8300941390829 0.088789795843776 0.430097443943535 GO:0015631 tubulin binding 16/534 385/18639 0.0415584415584416 1.45057638990223 0.088886805081664 0.430097443943535 GO:0099106 ion channel regulator activity 8/534 160/18639 0.05 1.74522471910112 0.0897295782456813 0.431853585139642 GO:0022834 ligand-gated channel activity 9/534 188/18639 0.0478723404255319 1.67095983743725 0.0921022076926291 0.439108528509515 GO:0015280 ligand-gated sodium channel activity 2/534 18/18639 0.111111111111111 3.87827715355805 0.0927006893520088 0.439108528509515 GO:0030228 lipoprotein particle receptor activity 2/534 18/18639 0.111111111111111 3.87827715355805 0.0927006893520088 0.439108528509515 GO:0004620 phospholipase activity 6/534 109/18639 0.055045871559633 1.92134831460674 0.0932127163150554 0.439222223474083 GO:0031625 ubiquitin protein ligase binding 13/534 302/18639 0.043046357615894 1.5025113475705 0.0955214056933424 0.447042068477604 GO:0019838 growth factor binding 7/534 136/18639 0.0514705882352941 1.79655485789822 0.0963624014273947 0.447042068477604 GO:0099094 ligand-gated monoatomic cation channel activity 7/534 136/18639 0.0514705882352941 1.79655485789822 0.0963624014273947 0.447042068477604 GO:0015026 coreceptor activity 4/534 61/18639 0.0655737704918033 2.28881930373918 0.0972735282914094 0.448954745960351 GO:0016922 nuclear receptor binding 7/534 137/18639 0.0510948905109489 1.78344131878947 0.0991994976588726 0.455507897413191 GO:0042578 phosphoric ester hydrolase activity 15/534 363/18639 0.0413223140495868 1.44233447859597 0.100647865797203 0.457705944185986 GO:0022821 solute:potassium antiporter activity 2/534 19/18639 0.105263157894737 3.67415730337079 0.10171243204133 0.457705944185986 GO:0042800 histone H3K4 methyltransferase activity 2/534 19/18639 0.105263157894737 3.67415730337079 0.10171243204133 0.457705944185986 GO:0050145 nucleoside monophosphate kinase activity 2/534 19/18639 0.105263157894737 3.67415730337079 0.10171243204133 0.457705944185986 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 19/534 484/18639 0.0392561983471074 1.37021775466617 0.10399136853279 0.465632993430404 GO:0015144 carbohydrate transmembrane transporter activity 3/534 40/18639 0.075 2.61783707865169 0.106190115507343 0.473124277012916 GO:0140297 DNA-binding transcription factor binding 19/534 488/18639 0.0389344262295082 1.35898646159514 0.110140835011352 0.482404540809797 GO:0016247 channel regulator activity 8/534 168/18639 0.0476190476190476 1.66211878009631 0.11055670243167 0.482404540809797 GO:0015095 magnesium ion transmembrane transporter activity 2/534 20/18639 0.1 3.49044943820225 0.110953044386253 0.482404540809797 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/534 20/18639 0.1 3.49044943820225 0.110953044386253 0.482404540809797 GO:0031418 L-ascorbic acid binding 2/534 20/18639 0.1 3.49044943820225 0.110953044386253 0.482404540809797 GO:0001530 lipopolysaccharide binding 3/534 41/18639 0.0731707317073171 2.55398739380652 0.112264986743111 0.483437741955979 GO:0140318 protein transporter activity 3/534 41/18639 0.0731707317073171 2.55398739380652 0.112264986743111 0.483437741955979 GO:0016758 hexosyltransferase activity 9/534 197/18639 0.0456852791878173 1.5946215707523 0.114013767619379 0.486673462049784 GO:0005261 monoatomic cation channel activity 14/534 341/18639 0.0410557184750733 1.43302909486309 0.114097889436116 0.486673462049784 GO:0001216 DNA-binding transcription activator activity 19/534 491/18639 0.0386965376782077 1.35068308199272 0.114897517191877 0.487772478644762 GO:0061134 peptidase regulator activity 10/534 226/18639 0.0442477876106195 1.54444665407179 0.116017105650453 0.48845459543462 GO:0141108 transporter regulator activity 8/534 170/18639 0.0470588235294118 1.64256444150694 0.116143648247788 0.48845459543462 GO:0019887 protein kinase regulator activity 11/534 255/18639 0.0431372549019608 1.50568407138136 0.116980665413328 0.489686506381372 GO:0035198 miRNA binding 3/534 42/18639 0.0714285714285714 2.49317817014446 0.118469048722867 0.492553950012735 GO:0005123 death receptor binding 2/534 21/18639 0.0952380952380952 3.32423756019262 0.12040207666978 0.492553950012735 GO:0005248 voltage-gated sodium channel activity 2/534 21/18639 0.0952380952380952 3.32423756019262 0.12040207666978 0.492553950012735 GO:0010314 phosphatidylinositol-5-phosphate binding 2/534 21/18639 0.0952380952380952 3.32423756019262 0.12040207666978 0.492553950012735 GO:0061891 calcium ion sensor activity 2/534 21/18639 0.0952380952380952 3.32423756019262 0.12040207666978 0.492553950012735 GO:0008200 ion channel inhibitor activity 3/534 43/18639 0.0697674418604651 2.43519728246668 0.124797312040209 0.503666281776627 GO:0008375 acetylglucosaminyltransferase activity 3/534 43/18639 0.0697674418604651 2.43519728246668 0.124797312040209 0.503666281776627 GO:0048156 tau protein binding 3/534 43/18639 0.0697674418604651 2.43519728246668 0.124797312040209 0.503666281776627 GO:0051219 phosphoprotein binding 5/534 93/18639 0.0537634408602151 1.87658571946357 0.128479512386063 0.515467139939255 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/534 22/18639 0.0909090909090909 3.17313585291113 0.130040059147696 0.515467139939255 GO:0050321 tau-protein kinase activity 2/534 22/18639 0.0909090909090909 3.17313585291113 0.130040059147696 0.515467139939255 GO:0140784 metal ion sensor activity 2/534 22/18639 0.0909090909090909 3.17313585291113 0.130040059147696 0.515467139939255 GO:0005548 phospholipid transporter activity 4/534 68/18639 0.0588235294117647 2.05320555188367 0.130585008784611 0.515467139939255 GO:0016248 channel inhibitor activity 3/534 44/18639 0.0681818181818182 2.37985188968335 0.131244755895947 0.515809084307217 GO:0042562 hormone binding 5/534 94/18639 0.0531914893617021 1.85662204159694 0.132717557401473 0.519329572440545 GO:0140303 intramembrane lipid transporter activity 3/534 45/18639 0.0666666666666667 2.32696629213483 0.137806339956746 0.534593560177031 GO:0141110 transporter inhibitor activity 3/534 45/18639 0.0666666666666667 2.32696629213483 0.137806339956746 0.534593560177031 GO:0140103 catalytic activity, acting on a glycoprotein 2/534 23/18639 0.0869565217391304 3.03517342452369 0.139848462855747 0.54018719558014 GO:0016782 transferase activity, transferring sulphur-containing groups 4/534 70/18639 0.0571428571428571 1.99454253611557 0.140869422302424 0.541805470393939 GO:0016757 glycosyltransferase activity 11/534 267/18639 0.0411985018726592 1.43801287716197 0.146264416940211 0.560161596792299 GO:0015149 hexose transmembrane transporter activity 2/534 24/18639 0.0833333333333333 2.90870786516854 0.149809661851472 0.560191611634774 GO:0015295 solute:proton symporter activity 2/534 24/18639 0.0833333333333333 2.90870786516854 0.149809661851472 0.560191611634774 GO:0055056 D-glucose transmembrane transporter activity 2/534 24/18639 0.0833333333333333 2.90870786516854 0.149809661851472 0.560191611634774 GO:0008170 N-methyltransferase activity 5/534 98/18639 0.0510204081632653 1.78084155010319 0.150279151202807 0.560191611634774 GO:0046873 metal ion transmembrane transporter activity 17/534 450/18639 0.0377777777777778 1.31861423220974 0.150989772313366 0.560191611634774 GO:0061749 forked DNA-dependent helicase activity 3/534 47/18639 0.0638297872340425 2.22794644991633 0.151251735141389 0.560191611634774 GO:0140938 histone H3 methyltransferase activity 3/534 47/18639 0.0638297872340425 2.22794644991633 0.151251735141389 0.560191611634774 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/534 47/18639 0.0638297872340425 2.22794644991633 0.151251735141389 0.560191611634774 GO:0009378 four-way junction helicase activity 3/534 48/18639 0.0625 2.1815308988764 0.158125463421444 0.575664828627275 GO:0036121 double-stranded DNA helicase activity 3/534 48/18639 0.0625 2.1815308988764 0.158125463421444 0.575664828627275 GO:0038187 pattern recognition receptor activity 3/534 48/18639 0.0625 2.1815308988764 0.158125463421444 0.575664828627275 GO:0043138 3'-5' DNA helicase activity 3/534 48/18639 0.0625 2.1815308988764 0.158125463421444 0.575664828627275 GO:0061135 endopeptidase regulator activity 8/534 184/18639 0.0434782608695652 1.51758671226185 0.159299555938722 0.575664828627275 GO:0005537 D-mannose binding 2/534 25/18639 0.08 2.7923595505618 0.15990689684091 0.575664828627275 GO:0017025 TBP-class protein binding 2/534 25/18639 0.08 2.7923595505618 0.15990689684091 0.575664828627275 GO:0045296 cadherin binding 13/534 334/18639 0.0389221556886228 1.35855816456974 0.164470466822682 0.584396244762744 GO:0001222 transcription corepressor binding 3/534 49/18639 0.0612244897959184 2.13700986012382 0.165093184562124 0.584396244762744 GO:0022804 active transmembrane transporter activity 17/534 457/18639 0.037199124726477 1.29841664003147 0.16544588702538 0.584396244762744 GO:0016298 lipase activity 6/534 130/18639 0.0461538461538462 1.61097666378565 0.170060607367176 0.584396244762744 GO:0004435 phosphatidylinositol phospholipase C activity 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0005112 Notch binding 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0015145 monosaccharide transmembrane transporter activity 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0019865 immunoglobulin binding 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0030247 polysaccharide binding 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0030507 spectrin binding 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0043548 phosphatidylinositol 3-kinase binding 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0052742 phosphatidylinositol kinase activity 2/534 26/18639 0.0769230769230769 2.68496110630942 0.170124240142043 0.584396244762744 GO:0033218 amide binding 10/534 247/18639 0.0404858299595142 1.41313742437338 0.173066606391187 0.589999794515409 GO:0035403 histone H3T6 kinase activity 10/534 247/18639 0.0404858299595142 1.41313742437338 0.173066606391187 0.589999794515409 GO:0001217 DNA-binding transcription repressor activity 11/534 278/18639 0.039568345323741 1.38111308705844 0.176148636497122 0.596479396222375 GO:0015079 potassium ion transmembrane transporter activity 7/534 160/18639 0.04375 1.52707162921348 0.176292799327946 0.596479396222375 GO:0005021 vascular endothelial growth factor receptor activity 3/534 51/18639 0.0588235294117647 2.05320555188367 0.179290691594844 0.601488539794904 GO:0004866 endopeptidase inhibitor activity 7/534 161/18639 0.0434782608695652 1.51758671226185 0.180115278271782 0.601488539794904 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/534 27/18639 0.0740740740740741 2.58551810237203 0.180446561938471 0.601488539794904 GO:0035255 ionotropic glutamate receptor binding 2/534 27/18639 0.0740740740740741 2.58551810237203 0.180446561938471 0.601488539794904 GO:0019199 transmembrane receptor protein kinase activity 4/534 78/18639 0.0512820512820513 1.78997407087295 0.184926503330055 0.614147059029704 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/534 52/18639 0.0576923076923077 2.01372082973207 0.186510616991642 0.617130717987051 GO:0019789 SUMO transferase activity 2/534 28/18639 0.0714285714285714 2.49317817014446 0.190859497778343 0.625226002345013 GO:0051119 sugar transmembrane transporter activity 2/534 28/18639 0.0714285714285714 2.49317817014446 0.190859497778343 0.625226002345013 GO:0015081 sodium ion transmembrane transporter activity 7/534 164/18639 0.0426829268292683 1.48982597972047 0.191788592160755 0.625226002345013 GO:0005544 calcium-dependent phospholipid binding 3/534 53/18639 0.0566037735849057 1.97572609709561 0.193804827562641 0.625226002345013 GO:0017046 peptide hormone binding 3/534 53/18639 0.0566037735849057 1.97572609709561 0.193804827562641 0.625226002345013 GO:0140296 general transcription initiation factor binding 3/534 53/18639 0.0566037735849057 1.97572609709561 0.193804827562641 0.625226002345013 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/534 54/18639 0.0555555555555556 1.93913857677903 0.201168518458538 0.625226002345013 GO:0004629 phospholipase C activity 2/534 29/18639 0.0689655172413793 2.407206509105 0.201349417275123 0.625226002345013 GO:0106222 lncRNA binding 2/534 29/18639 0.0689655172413793 2.407206509105 0.201349417275123 0.625226002345013 GO:0001618 virus receptor activity 4/534 81/18639 0.0493827160493827 1.72367873491469 0.202487621381256 0.625226002345013 GO:0019207 kinase regulator activity 11/534 287/18639 0.0383275261324042 1.33780292056532 0.202587131430919 0.625226002345013 GO:0140272 exogenous protein binding 4/534 82/18639 0.0487804878048781 1.70265826253768 0.208448532128964 0.625226002345013 GO:0030414 peptidase inhibitor activity 7/534 169/18639 0.0414201183431953 1.44574828801277 0.211891970003911 0.625226002345013 GO:0001968 fibronectin binding 2/534 30/18639 0.0666666666666667 2.32696629213483 0.211903393968185 0.625226002345013 GO:0070566 adenylyltransferase activity 2/534 30/18639 0.0666666666666667 2.32696629213483 0.211903393968185 0.625226002345013 GO:0016829 lyase activity 8/534 200/18639 0.04 1.3961797752809 0.216385616207205 0.625226002345013 GO:0005216 monoatomic ion channel activity 16/534 448/18639 0.0357142857142857 1.24658908507223 0.216926322773451 0.625226002345013 GO:0016887 ATP hydrolysis activity 15/534 417/18639 0.0359712230215827 1.25555735187131 0.218354692618572 0.625226002345013 GO:0005200 structural constituent of cytoskeleton 5/534 112/18639 0.0446428571428571 1.55823635634029 0.218421339531992 0.625226002345013 GO:0017147 Wnt-protein binding 2/534 31/18639 0.0645161290322581 2.25190286335629 0.222509176302677 0.625226002345013 GO:0004601 peroxidase activity 3/534 57/18639 0.0526315789473684 1.83707865168539 0.223629357319289 0.625226002345013 GO:0016504 peptidase activator activity 3/534 57/18639 0.0526315789473684 1.83707865168539 0.223629357319289 0.625226002345013 GO:0017116 single-stranded DNA helicase activity 3/534 58/18639 0.0517241379310345 1.80540488182875 0.231224196563886 0.625226002345013 GO:0061980 regulatory RNA binding 3/534 58/18639 0.0517241379310345 1.80540488182875 0.231224196563886 0.625226002345013 GO:0019903 protein phosphatase binding 6/534 144/18639 0.0416666666666667 1.45435393258427 0.232144200741216 0.625226002345013 GO:0051059 NF-kappaB binding 2/534 32/18639 0.0625 2.1815308988764 0.23315515968944 0.625226002345013 GO:0106310 protein serine kinase activity 13/534 361/18639 0.03601108033241 1.25694855115316 0.23782932588105 0.625226002345013 GO:0015459 potassium channel regulator activity 3/534 59/18639 0.0508474576271186 1.77480479908589 0.238865486442533 0.625226002345013 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/534 59/18639 0.0508474576271186 1.77480479908589 0.238865486442533 0.625226002345013 GO:0070063 RNA polymerase binding 3/534 59/18639 0.0508474576271186 1.77480479908589 0.238865486442533 0.625226002345013 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/534 268/18639 0.0373134328358209 1.30240650679188 0.240854559977979 0.625226002345013 GO:0071889 14-3-3 protein binding 2/534 33/18639 0.0606060606060606 2.11542390194076 0.243830359607098 0.625226002345013 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/534 60/18639 0.05 1.74522471910112 0.246548847933065 0.625226002345013 GO:0000182 rDNA binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0004090 carbonyl reductase (NADPH) activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0005131 growth hormone receptor binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0005381 iron ion transmembrane transporter activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0008239 dipeptidyl-peptidase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0015203 polyamine transmembrane transporter activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0016868 intramolecular phosphotransferase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0031996 thioesterase binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0032395 MHC class II receptor activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0043121 neurotrophin binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0043422 protein kinase B binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0050815 phosphoserine residue binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0051378 serotonin binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0070739 protein-glutamic acid ligase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0070740 tubulin-glutamic acid ligase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0099122 RNA polymerase II C-terminal domain binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0140135 mechanosensitive monoatomic cation channel activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0140999 histone H3K4 trimethyltransferase activity 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:1905394 retromer complex binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:1990763 arrestin family protein binding 1/534 10/18639 0.1 3.49044943820225 0.252298465371914 0.625226002345013 GO:0090482 vitamin transmembrane transporter activity 2/534 34/18639 0.0588235294117647 2.05320555188367 0.254524385709713 0.625226002345013 GO:0003712 transcription coregulator activity 17/534 495/18639 0.0343434343434343 1.19874021109976 0.255386943356433 0.625226002345013 GO:0032182 ubiquitin-like protein binding 5/534 120/18639 0.0416666666666667 1.45435393258427 0.260978216452832 0.625226002345013 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 9/534 243/18639 0.037037037037037 1.29275905118602 0.263048217786421 0.625226002345013 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/534 91/18639 0.043956043956044 1.53426348931967 0.264048627472955 0.625226002345013 GO:0043015 gamma-tubulin binding 2/534 35/18639 0.0571428571428571 1.99454253611557 0.265227416904629 0.625226002345013 GO:0140566 histone reader activity 2/534 35/18639 0.0571428571428571 1.99454253611557 0.265227416904629 0.625226002345013 GO:0005126 cytokine receptor binding 10/534 275/18639 0.0363636363636364 1.26925434116445 0.265364605895104 0.625226002345013 GO:0008017 microtubule binding 10/534 276/18639 0.036231884057971 1.26465559355154 0.268930590475139 0.625226002345013 GO:0005507 copper ion binding 3/534 63/18639 0.0476190476190476 1.66211878009631 0.269808833745059 0.625226002345013 GO:0004676 3-phosphoinositide-dependent protein kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0004711 ribosomal protein S6 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0035175 histone H3S10 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0035979 histone H2AXS139 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0044022 histone H3S28 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0044023 histone H4S1 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0044024 histone H2AS1 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0044025 histone H2BS14 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0072354 histone H3T3 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0072371 histone H2AS121 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0072518 Rho-dependent protein serine/threonine kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0140823 histone H2BS36 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0140855 histone H3S57 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0140995 histone H2A kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0140997 histone H4 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0140998 histone H2B kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:1990244 histone H2AT120 kinase activity 9/534 245/18639 0.036734693877551 1.2822059160743 0.270635854624411 0.625226002345013 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0001851 complement component C3b binding 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0002162 dystroglycan binding 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0005225 volume-sensitive anion channel activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0008046 axon guidance receptor activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0008526 phosphatidylinositol transfer activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0015173 aromatic amino acid transmembrane transporter activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0019107 myristoyltransferase activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0035252 UDP-xylosyltransferase activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0042285 xylosyltransferase activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0042608 T cell receptor binding 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0050998 nitric-oxide synthase binding 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0097493 structural molecule activity conferring elasticity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0140031 phosphorylation-dependent protein binding 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0180030 inositol phosphate kinase activity 1/534 11/18639 0.0909090909090909 3.17313585291113 0.273731318423145 0.625226002345013 GO:0004677 DNA-dependent protein kinase activity 9/534 246/18639 0.0365853658536585 1.27699369690326 0.274454141860668 0.625226002345013 GO:0140857 histone H3T45 kinase activity 9/534 246/18639 0.0365853658536585 1.27699369690326 0.274454141860668 0.625226002345013 GO:0003774 cytoskeletal motor activity 6/534 153/18639 0.0392156862745098 1.36880370125578 0.275301724540084 0.625226002345013 GO:0035402 histone H3T11 kinase activity 9/534 247/18639 0.0364372469635627 1.27182368193604 0.278288124294388 0.625226002345013 GO:0042393 histone binding 9/534 247/18639 0.0364372469635627 1.27182368193604 0.278288124294388 0.625226002345013 GO:0004679 AMP-activated protein kinase activity 9/534 248/18639 0.0362903225806452 1.26669536063791 0.282137336463993 0.625226002345013 GO:0005267 potassium channel activity 5/534 124/18639 0.0403225806451613 1.40743928959768 0.282945622341308 0.625226002345013 GO:0140104 molecular carrier activity 9/534 249/18639 0.036144578313253 1.26160823067551 0.28600131116772 0.625226002345013 GO:0019213 deacetylase activity 2/534 37/18639 0.0540540540540541 1.88672942605527 0.286623913453343 0.625226002345013 GO:0004032 aldose reductase (NADPH) activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0004875 complement receptor activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0005025 transforming growth factor beta receptor activity, type I 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0005026 transforming growth factor beta receptor activity, type II 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0005049 nuclear export signal receptor activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0005095 GTPase inhibitor activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0008179 adenylate cyclase binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0008504 monoamine transmembrane transporter activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0008603 cAMP-dependent protein kinase regulator activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0015368 calcium:monoatomic cation antiporter activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0016208 AMP binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0016361 activin receptor activity, type I 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0016362 activin receptor activity, type II 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0016840 carbon-nitrogen lyase activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0017002 activin receptor activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0017166 vinculin binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0031543 peptidyl-proline dioxygenase activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0035251 UDP-glucosyltransferase activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0045295 gamma-catenin binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0070008 serine-type exopeptidase activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0097371 MDM2/MDM4 family protein binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0097677 STAT family protein binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:1990459 transferrin receptor binding 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:1990817 poly(A) RNA polymerase activity 1/534 12/18639 0.0833333333333333 2.90870786516854 0.294550916660317 0.625226002345013 GO:0004896 cytokine receptor activity 4/534 96/18639 0.0416666666666667 1.45435393258427 0.296051324393381 0.626932216362455 GO:0043531 ADP binding 2/534 38/18639 0.0526315789473684 1.83707865168539 0.2973003714961 0.628099376400212 GO:0042054 histone methyltransferase activity 3/534 67/18639 0.0447761194029851 1.56288780815026 0.301160574384107 0.633281581648824 GO:0050840 extracellular matrix binding 3/534 67/18639 0.0447761194029851 1.56288780815026 0.301160574384107 0.633281581648824 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/534 39/18639 0.0512820512820513 1.78997407087295 0.307951776425267 0.638056976483039 GO:0030145 manganese ion binding 3/534 68/18639 0.0441176470588235 1.53990416391276 0.309033292796391 0.638056976483039 GO:0004993 G protein-coupled serotonin receptor activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0005542 folic acid binding 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0008253 5'-nucleotidase activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0031994 insulin-like growth factor I binding 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0032396 inhibitory MHC class I receptor activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0035325 Toll-like receptor binding 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0046974 histone H3K9 methyltransferase activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0046975 histone H3K36 methyltransferase activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0051011 microtubule minus-end binding 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0070123 transforming growth factor beta receptor activity, type III 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0089720 caspase binding 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0140333 glycerophospholipid flippase activity 1/534 13/18639 0.0769230769230769 2.68496110630942 0.314774775064966 0.638056976483039 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/534 130/18639 0.0384615384615385 1.34248055315471 0.316500597616657 0.63901893495313 GO:0016279 protein-lysine N-methyltransferase activity 3/534 69/18639 0.0434782608695652 1.51758671226185 0.316912652706448 0.63901893495313 GO:0071949 FAD binding 2/534 40/18639 0.05 1.74522471910112 0.318570811210421 0.63901893495313 GO:0043130 ubiquitin binding 4/534 100/18639 0.04 1.3961797752809 0.321986546188581 0.63901893495313 GO:0016278 lysine N-methyltransferase activity 3/534 70/18639 0.0428571428571429 1.49590690208668 0.324795185411106 0.63901893495313 GO:0001727 lipid kinase activity 2/534 41/18639 0.0487804878048781 1.70265826253768 0.329150597080539 0.63901893495313 GO:0008227 G protein-coupled amine receptor activity 2/534 41/18639 0.0487804878048781 1.70265826253768 0.329150597080539 0.63901893495313 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/534 41/18639 0.0487804878048781 1.70265826253768 0.329150597080539 0.63901893495313 GO:0140828 metal cation:monoatomic cation antiporter activity 2/534 41/18639 0.0487804878048781 1.70265826253768 0.329150597080539 0.63901893495313 GO:0140299 molecular sensor activity 3/534 71/18639 0.0422535211267606 1.47483779078968 0.332677518351255 0.63901893495313 GO:0004065 arylsulfatase activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0008174 mRNA methyltransferase activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0008331 high voltage-gated calcium channel activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0008474 palmitoyl-(protein) hydrolase activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0008559 ABC-type xenobiotic transporter activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0015386 potassium:proton antiporter activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0016530 metallochaperone activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0031404 chloride ion binding 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0034236 protein kinase A catalytic subunit binding 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0042043 neurexin family protein binding 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0042813 Wnt receptor activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0043176 amine binding 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0046030 inositol trisphosphate phosphatase activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0071933 Arp2/3 complex binding 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0098599 palmitoyl hydrolase activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0098821 BMP receptor activity 1/534 14/18639 0.0714285714285714 2.49317817014446 0.334419909292138 0.63901893495313 GO:0008307 structural constituent of muscle 2/534 42/18639 0.0476190476190476 1.66211878009631 0.339684674498422 0.644970900946371 GO:0043175 RNA polymerase core enzyme binding 2/534 42/18639 0.0476190476190476 1.66211878009631 0.339684674498422 0.644970900946371 GO:0051879 Hsp90 protein binding 2/534 42/18639 0.0476190476190476 1.66211878009631 0.339684674498422 0.644970900946371 GO:0001664 G protein-coupled receptor binding 10/534 297/18639 0.0336700336700337 1.1752355010782 0.346688388517153 0.649290948758106 GO:0004521 RNA endonuclease activity 3/534 73/18639 0.0410958904109589 1.43443127597353 0.348428575892725 0.649290948758106 GO:0005245 voltage-gated calcium channel activity 2/534 43/18639 0.0465116279069767 1.62346485497779 0.350166984862238 0.649290948758106 GO:0002020 protease binding 5/534 136/18639 0.0367647058823529 1.2832534699273 0.350514693406375 0.649290948758106 GO:0016779 nucleotidyltransferase activity 5/534 136/18639 0.0367647058823529 1.2832534699273 0.350514693406375 0.649290948758106 GO:0005041 low-density lipoprotein particle receptor activity 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0008252 nucleotidase activity 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0010181 FMN binding 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0015929 hexosaminidase activity 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0030553 cGMP binding 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0033130 acetylcholine receptor binding 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0051371 muscle alpha-actinin binding 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0120283 protein serine/threonine kinase binding 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0140776 protein-containing complex destabilizing activity 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0141050 histone H3K deacetylase activity 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0141051 histone H4K deacetylase activity 1/534 15/18639 0.0666666666666667 2.32696629213483 0.353502849879413 0.649290948758106 GO:0003678 DNA helicase activity 3/534 74/18639 0.0405405405405405 1.41504706954145 0.356291036243545 0.653079292503442 GO:0001046 core promoter sequence-specific DNA binding 2/534 44/18639 0.0454545454545455 1.58656792645557 0.360591852908252 0.658281273057661 GO:0019205 nucleobase-containing compound kinase activity 2/534 44/18639 0.0454545454545455 1.58656792645557 0.360591852908252 0.658281273057661 GO:0070851 growth factor receptor binding 5/534 139/18639 0.0359712230215827 1.25555735187131 0.36760439492657 0.66304097118237 GO:0004708 MAP kinase kinase activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0005024 transforming growth factor beta receptor activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0005159 insulin-like growth factor receptor binding 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0005521 lamin binding 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0008142 oxysterol binding 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0015385 sodium:proton antiporter activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0016722 oxidoreductase activity, acting on metal ions 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0034450 ubiquitin-ubiquitin ligase activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0140327 flippase activity 1/534 16/18639 0.0625 2.1815308988764 0.37203965605233 0.66304097118237 GO:0140030 modification-dependent protein binding 6/534 173/18639 0.0346820809248555 1.21056049879847 0.376200431066245 0.667985093152528 GO:0004180 carboxypeptidase activity 2/534 46/18639 0.0434782608695652 1.51758671226185 0.381248376807727 0.667985093152528 GO:0030276 clathrin binding 2/534 46/18639 0.0434782608695652 1.51758671226185 0.381248376807727 0.667985093152528 GO:0022832 voltage-gated channel activity 6/534 175/18639 0.0342857142857143 1.19672552166934 0.386448880403882 0.667985093152528 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0004659 prenyltransferase activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0005092 GDP-dissociation inhibitor activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0008484 sulfuric ester hydrolase activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0008569 minus-end-directed microtubule motor activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0009881 photoreceptor activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0016805 dipeptidase activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0031489 myosin V binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0032183 SUMO binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0036041 long-chain fatty acid binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0045125 bioactive lipid receptor activity 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0046965 nuclear retinoid X receptor binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0048038 quinone binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0070402 NADPH binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0070403 NAD+ binding 1/534 17/18639 0.0588235294117647 2.05320555188367 0.390045929137657 0.667985093152528 GO:0022843 voltage-gated monoatomic cation channel activity 5/534 143/18639 0.034965034965035 1.22043686650428 0.3904001766647 0.667985093152528 GO:0099095 ligand-gated monoatomic anion channel activity 2/534 47/18639 0.0425531914893617 1.48529763327755 0.391470449770676 0.668545360139674 GO:0046332 SMAD binding 3/534 79/18639 0.0379746835443038 1.32548712843123 0.39535595267003 0.673902192051188 GO:0048306 calcium-dependent protein binding 3/534 80/18639 0.0375 1.30891853932584 0.403100519690184 0.67423371881631 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0004706 JUN kinase kinase kinase activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0004970 glutamate-gated receptor activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0008525 phosphatidylcholine transporter activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0016854 racemase and epimerase activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0031690 adrenergic receptor binding 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0032393 MHC class I receptor activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0035615 clathrin adaptor activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0050811 GABA receptor binding 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0098641 cadherin binding involved in cell-cell adhesion 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:1901611 phosphatidylglycerol binding 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:1990381 ubiquitin-specific protease binding 1/534 18/18639 0.0555555555555556 1.93913857677903 0.407536825595636 0.67423371881631 GO:0030971 receptor tyrosine kinase binding 3/534 81/18639 0.037037037037037 1.29275905118602 0.410816400394373 0.67735395193956 GO:0016763 pentosyltransferase activity 2/534 49/18639 0.0408163265306122 1.42467324008255 0.411680679678821 0.67735395193956 GO:0035254 glutamate receptor binding 2/534 49/18639 0.0408163265306122 1.42467324008255 0.411680679678821 0.67735395193956 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0005229 intracellularly calcium-gated chloride channel activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0005520 insulin-like growth factor binding 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0008381 mechanosensitive monoatomic ion channel activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0015245 fatty acid transmembrane transporter activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0046527 glucosyltransferase activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0046624 sphingolipid transporter activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0099589 serotonin receptor activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0141147 intracellularly calcium-gated channel activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:1990380 K48-linked deubiquitinase activity 1/534 19/18639 0.0526315789473684 1.83707865168539 0.424527069681987 0.684721080132236 GO:0019842 vitamin binding 5/534 150/18639 0.0333333333333333 1.16348314606742 0.430108730043109 0.69248274962218 GO:0051117 ATPase binding 3/534 84/18639 0.0357142857142857 1.24658908507223 0.433768981600019 0.697128720428602 GO:0015078 proton transmembrane transporter activity 6/534 185/18639 0.0324324324324324 1.13203765563316 0.437548555282523 0.698101887331837 GO:0022853 active monoatomic ion transmembrane transporter activity 4/534 118/18639 0.0338983050847458 1.18320319939059 0.438863841995766 0.698101887331837 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/534 20/18639 0.05 1.74522471910112 0.441030965750184 0.698101887331837 GO:0016004 phospholipase activator activity 1/534 20/18639 0.05 1.74522471910112 0.441030965750184 0.698101887331837 GO:0016408 C-acyltransferase activity 1/534 20/18639 0.05 1.74522471910112 0.441030965750184 0.698101887331837 GO:0016505 peptidase activator activity involved in apoptotic process 1/534 20/18639 0.05 1.74522471910112 0.441030965750184 0.698101887331837 GO:0030742 GTP-dependent protein binding 1/534 20/18639 0.05 1.74522471910112 0.441030965750184 0.698101887331837 GO:0052745 inositol phosphate phosphatase activity 1/534 20/18639 0.05 1.74522471910112 0.441030965750184 0.698101887331837 GO:0030159 signaling receptor complex adaptor activity 2/534 52/18639 0.0384615384615385 1.34248055315471 0.441355526546462 0.698101887331837 GO:0061775 cohesin loader activity 5/534 153/18639 0.0326797385620915 1.14066975104649 0.446978647386598 0.705425228524859 GO:0016209 antioxidant activity 3/534 86/18639 0.0348837209302326 1.21759864123334 0.448886742823586 0.705425228524859 GO:0005246 calcium channel regulator activity 2/534 53/18639 0.0377358490566038 1.31715073139707 0.451063397094847 0.705425228524859 GO:0003713 transcription coactivator activity 8/534 256/18639 0.03125 1.0907654494382 0.451998146696412 0.705425228524859 GO:0001846 opsonin binding 1/534 21/18639 0.0476190476190476 1.66211878009631 0.457062410204203 0.705425228524859 GO:0008373 sialyltransferase activity 1/534 21/18639 0.0476190476190476 1.66211878009631 0.457062410204203 0.705425228524859 GO:0036122 BMP binding 1/534 21/18639 0.0476190476190476 1.66211878009631 0.457062410204203 0.705425228524859 GO:0051428 peptide hormone receptor binding 1/534 21/18639 0.0476190476190476 1.66211878009631 0.457062410204203 0.705425228524859 GO:0140312 cargo adaptor activity 1/534 21/18639 0.0476190476190476 1.66211878009631 0.457062410204203 0.705425228524859 GO:0004386 helicase activity 5/534 155/18639 0.032258064516129 1.12595143167814 0.45815568438979 0.705425228524859 GO:0003925 G protein activity 2/534 54/18639 0.037037037037037 1.29275905118602 0.460674738580858 0.705425228524859 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/534 54/18639 0.037037037037037 1.29275905118602 0.460674738580858 0.705425228524859 GO:0050661 NADP binding 2/534 54/18639 0.037037037037037 1.29275905118602 0.460674738580858 0.705425228524859 GO:0051287 NAD binding 2/534 54/18639 0.037037037037037 1.29275905118602 0.460674738580858 0.705425228524859 GO:0140463 chromatin-protein adaptor activity 2/534 54/18639 0.037037037037037 1.29275905118602 0.460674738580858 0.705425228524859 GO:0098632 cell-cell adhesion mediator activity 2/534 55/18639 0.0363636363636364 1.26925434116445 0.470187108146228 0.705425228524859 GO:0004407 histone deacetylase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0008970 phospholipase A1 activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0016881 acid-amino acid ligase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0032931 histone H3K56 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0033558 protein lysine deacetylase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0043992 histone H3K9 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0043993 histone H3K18 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0043994 histone H3K23 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0043999 histone H2AK5 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0044012 histone H2AK9 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0044014 histone H2BK5 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0044015 histone H2BK12 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0044016 histone H3K4 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0044017 histone H3K27 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0044018 histone H3K36 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0046972 histone H4K16 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0061133 endopeptidase activator activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0140908 histone H3K122 acetyltransferase activity 1/534 22/18639 0.0454545454545455 1.58656792645557 0.472634903111656 0.705425228524859 GO:0140658 ATP-dependent chromatin remodeler activity 5/534 158/18639 0.0316455696202532 1.10457260702603 0.474798172585336 0.70748072073974 GO:0019001 guanyl nucleotide binding 12/534 400/18639 0.03 1.04713483146067 0.476804648004858 0.7081257148587 GO:0032561 guanyl ribonucleotide binding 12/534 400/18639 0.03 1.04713483146067 0.476804648004858 0.7081257148587 GO:0030170 pyridoxal phosphate binding 2/534 56/18639 0.0357142857142857 1.24658908507223 0.479598281483978 0.711101241080034 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:0017134 fibroblast growth factor binding 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:0031681 G-protein beta-subunit binding 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:0044013 histone H2B acetyltransferase activity 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:0070577 lysine-acetylated histone binding 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/534 23/18639 0.0434782608695652 1.51758671226185 0.487761559486925 0.714959940616013 GO:0070279 vitamin B6 binding 2/534 57/18639 0.0350877192982456 1.2247191011236 0.488906242362694 0.715472549799064 GO:0008083 growth factor activity 5/534 162/18639 0.0308641975308642 1.07729920932168 0.496721753625338 0.722379565859929 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0005540 hyaluronic acid binding 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0035035 histone acetyltransferase binding 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0043998 histone H2A acetyltransferase activity 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0060229 lipase activator activity 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0070300 phosphatidic acid binding 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0140033 acetylation-dependent protein binding 1/534 24/18639 0.0416666666666667 1.45435393258427 0.502455120253684 0.722379565859929 GO:0031593 polyubiquitin modification-dependent protein binding 2/534 59/18639 0.0338983050847458 1.18320319939059 0.50720544225847 0.724384994713854 GO:0036002 pre-mRNA binding 2/534 59/18639 0.0338983050847458 1.18320319939059 0.50720544225847 0.724384994713854 GO:0004867 serine-type endopeptidase inhibitor activity 3/534 95/18639 0.0315789473684211 1.10224719101124 0.514673134895394 0.724384994713854 GO:0008276 protein methyltransferase activity 3/534 95/18639 0.0315789473684211 1.10224719101124 0.514673134895394 0.724384994713854 GO:0001098 basal transcription machinery binding 2/534 60/18639 0.0333333333333333 1.16348314606742 0.516193600683484 0.724384994713854 GO:0001099 basal RNA polymerase II transcription machinery binding 2/534 60/18639 0.0333333333333333 1.16348314606742 0.516193600683484 0.724384994713854 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/534 60/18639 0.0333333333333333 1.16348314606742 0.516193600683484 0.724384994713854 GO:0001848 complement binding 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0004709 MAP kinase kinase kinase activity 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0015645 fatty acid ligase activity 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0015662 P-type ion transporter activity 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0042974 nuclear retinoic acid receptor binding 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0120020 cholesterol transfer activity 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0120515 fatty acid-CoA ligase activity 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0140358 P-type transmembrane transporter activity 1/534 25/18639 0.04 1.3961797752809 0.516727962895882 0.724384994713854 GO:0005525 GTP binding 11/534 378/18639 0.0291005291005291 1.0157392545033 0.522084355084911 0.730755706961772 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/534 167/18639 0.029940119760479 1.04504474197672 0.523626019001467 0.731524969938674 GO:0016791 phosphatase activity 8/534 273/18639 0.0293040293040293 1.02284232621311 0.524384439214936 0.731524969938674 GO:0016836 hydro-lyase activity 2/534 61/18639 0.0327868852459016 1.14440965186959 0.525072367311537 0.731524969938674 GO:0008066 glutamate receptor activity 1/534 26/18639 0.0384615384615385 1.34248055315471 0.530592111806036 0.732412424272136 GO:0008157 protein phosphatase 1 binding 1/534 26/18639 0.0384615384615385 1.34248055315471 0.530592111806036 0.732412424272136 GO:0050681 nuclear androgen receptor binding 1/534 26/18639 0.0384615384615385 1.34248055315471 0.530592111806036 0.732412424272136 GO:0051139 metal cation:proton antiporter activity 1/534 26/18639 0.0384615384615385 1.34248055315471 0.530592111806036 0.732412424272136 GO:0097602 cullin family protein binding 1/534 26/18639 0.0384615384615385 1.34248055315471 0.530592111806036 0.732412424272136 GO:0120014 phospholipid transfer activity 1/534 26/18639 0.0384615384615385 1.34248055315471 0.530592111806036 0.732412424272136 GO:0003714 transcription corepressor activity 6/534 204/18639 0.0294117647058824 1.02660277594184 0.531806974084896 0.732965201648402 GO:0015179 L-amino acid transmembrane transporter activity 2/534 62/18639 0.032258064516129 1.12595143167814 0.533840623292412 0.734643059576714 GO:0005249 voltage-gated potassium channel activity 3/534 98/18639 0.0306122448979592 1.06850493006191 0.535660403026122 0.736021927822152 GO:0015297 antiporter activity 4/534 135/18639 0.0296296296296296 1.03420724094881 0.543433887332071 0.743024770114513 GO:0008320 protein transmembrane transporter activity 1/534 27/18639 0.037037037037037 1.29275905118602 0.544059248339404 0.743024770114513 GO:0016405 CoA-ligase activity 1/534 27/18639 0.037037037037037 1.29275905118602 0.544059248339404 0.743024770114513 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/534 27/18639 0.037037037037037 1.29275905118602 0.544059248339404 0.743024770114513 GO:0005244 voltage-gated monoatomic ion channel activity 5/534 173/18639 0.0289017341040462 1.00880041566539 0.555060667714736 0.754025035374685 GO:0005242 inward rectifier potassium channel activity 1/534 28/18639 0.0357142857142857 1.24658908507223 0.557140720582406 0.754025035374685 GO:0016866 intramolecular transferase activity 1/534 28/18639 0.0357142857142857 1.24658908507223 0.557140720582406 0.754025035374685 GO:0036408 histone H3K14 acetyltransferase activity 1/534 28/18639 0.0357142857142857 1.24658908507223 0.557140720582406 0.754025035374685 GO:0051393 alpha-actinin binding 1/534 28/18639 0.0357142857142857 1.24658908507223 0.557140720582406 0.754025035374685 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/534 28/18639 0.0357142857142857 1.24658908507223 0.557140720582406 0.754025035374685 GO:0160215 deacylase activity 2/534 65/18639 0.0307692307692308 1.07398444252377 0.559473394616507 0.7559380028138 GO:0008094 ATP-dependent activity, acting on DNA 6/534 210/18639 0.0285714285714286 0.997271268057785 0.560234053196449 0.7559380028138 GO:0008238 exopeptidase activity 3/534 102/18639 0.0294117647058824 1.02660277594184 0.562823443994754 0.757161583849445 GO:0015171 amino acid transmembrane transporter activity 3/534 102/18639 0.0294117647058824 1.02660277594184 0.562823443994754 0.757161583849445 GO:0004721 phosphoprotein phosphatase activity 5/534 175/18639 0.0285714285714286 0.997271268057785 0.565311147915724 0.759373183767391 GO:0005253 monoatomic anion channel activity 3/534 103/18639 0.029126213592233 1.01663575869968 0.569461806372861 0.76092403198671 GO:0003785 actin monomer binding 1/534 29/18639 0.0344827586206897 1.2036032545525 0.569847552843381 0.76092403198671 GO:0010484 histone H3 acetyltransferase activity 1/534 29/18639 0.0344827586206897 1.2036032545525 0.569847552843381 0.76092403198671 GO:0035250 UDP-galactosyltransferase activity 1/534 29/18639 0.0344827586206897 1.2036032545525 0.569847552843381 0.76092403198671 GO:0016500 protein-hormone receptor activity 2/534 67/18639 0.0298507462686567 1.04192520543351 0.57599539835581 0.767993864474414 GO:0031210 phosphatidylcholine binding 1/534 30/18639 0.0333333333333333 1.16348314606742 0.58219045487356 0.769658335603666 GO:0043995 histone H4K5 acetyltransferase activity 1/534 30/18639 0.0333333333333333 1.16348314606742 0.58219045487356 0.769658335603666 GO:0043996 histone H4K8 acetyltransferase activity 1/534 30/18639 0.0333333333333333 1.16348314606742 0.58219045487356 0.769658335603666 GO:0043997 histone H4K12 acetyltransferase activity 1/534 30/18639 0.0333333333333333 1.16348314606742 0.58219045487356 0.769658335603666 GO:0051721 protein phosphatase 2A binding 1/534 30/18639 0.0333333333333333 1.16348314606742 0.58219045487356 0.769658335603666 GO:0020037 heme binding 4/534 142/18639 0.028169014084507 0.983225193859788 0.583506294271295 0.769658335603666 GO:0140223 general transcription initiation factor activity 2/534 68/18639 0.0294117647058824 1.02660277594184 0.584085159130338 0.769658335603666 GO:1990841 promoter-specific chromatin binding 2/534 68/18639 0.0294117647058824 1.02660277594184 0.584085159130338 0.769658335603666 GO:0016853 isomerase activity 5/534 180/18639 0.0277777777777778 0.969569288389513 0.590398724983177 0.776840427609444 GO:0016878 acid-thiol ligase activity 1/534 31/18639 0.032258064516129 1.12595143167814 0.594179830825923 0.779536221200191 GO:0047499 calcium-independent phospholipase A2 activity 1/534 31/18639 0.032258064516129 1.12595143167814 0.594179830825923 0.779536221200191 GO:0008378 galactosyltransferase activity 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0015106 bicarbonate transmembrane transporter activity 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0022884 macromolecule transmembrane transporter activity 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0042910 xenobiotic transmembrane transporter activity 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0047498 calcium-dependent phospholipase A2 activity 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0140142 nucleocytoplasmic carrier activity 1/534 32/18639 0.03125 1.0907654494382 0.605825787959358 0.786786737609555 GO:0004222 metalloendopeptidase activity 3/534 110/18639 0.0272727272727273 0.95194075587334 0.614147461267576 0.79459847007987 GO:0005518 collagen binding 2/534 72/18639 0.0277777777777778 0.969569288389513 0.615299138257672 0.79459847007987 GO:0042379 chemokine receptor binding 2/534 72/18639 0.0277777777777778 0.969569288389513 0.615299138257672 0.79459847007987 GO:0046982 protein heterodimerization activity 10/534 369/18639 0.02710027100271 0.945921256965379 0.615757390338462 0.79459847007987 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/534 33/18639 0.0303030303030303 1.05771195097038 0.617138145095366 0.79459847007987 GO:0019956 chemokine binding 1/534 33/18639 0.0303030303030303 1.05771195097038 0.617138145095366 0.79459847007987 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/534 73/18639 0.0273972602739726 0.956287517315684 0.62281661888767 0.800764224284148 GO:0015035 protein-disulfide reductase activity 1/534 34/18639 0.0294117647058824 1.02660277594184 0.628126440834325 0.801227703215143 GO:0051427 hormone receptor binding 1/534 34/18639 0.0294117647058824 1.02660277594184 0.628126440834325 0.801227703215143 GO:0031491 nucleosome binding 2/534 74/18639 0.027027027027027 0.943364713027634 0.630220107294452 0.801227703215143 GO:0000510 H3-H4 histone complex chaperone activity 4/534 151/18639 0.0264900662251656 0.924622367735695 0.6319140081333 0.801227703215143 GO:0140584 chromatin extrusion motor activity 4/534 151/18639 0.0264900662251656 0.924622367735695 0.6319140081333 0.801227703215143 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/534 151/18639 0.0264900662251656 0.924622367735695 0.6319140081333 0.801227703215143 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/534 151/18639 0.0264900662251656 0.924622367735695 0.6319140081333 0.801227703215143 GO:0015616 DNA translocase activity 4/534 152/18639 0.0263157894736842 0.918539325842697 0.637063892395529 0.801227703215143 GO:0046906 tetrapyrrole binding 4/534 152/18639 0.0263157894736842 0.918539325842697 0.637063892395529 0.801227703215143 GO:0140674 ATP-dependent histone chaperone activity 4/534 152/18639 0.0263157894736842 0.918539325842697 0.637063892395529 0.801227703215143 GO:0003725 double-stranded RNA binding 2/534 75/18639 0.0266666666666667 0.930786516853933 0.637509952212915 0.801227703215143 GO:0019003 GDP binding 2/534 75/18639 0.0266666666666667 0.930786516853933 0.637509952212915 0.801227703215143 GO:0004623 phospholipase A2 activity 1/534 35/18639 0.0285714285714286 0.997271268057785 0.638799941538139 0.801227703215143 GO:0010485 histone H4 acetyltransferase activity 1/534 35/18639 0.0285714285714286 0.997271268057785 0.638799941538139 0.801227703215143 GO:0016229 steroid dehydrogenase activity 1/534 35/18639 0.0285714285714286 0.997271268057785 0.638799941538139 0.801227703215143 GO:0061631 ubiquitin conjugating enzyme activity 1/534 35/18639 0.0285714285714286 0.997271268057785 0.638799941538139 0.801227703215143 GO:0017022 myosin binding 2/534 76/18639 0.0263157894736842 0.918539325842697 0.644686575863841 0.801227703215143 GO:0051536 iron-sulfur cluster binding 2/534 76/18639 0.0263157894736842 0.918539325842697 0.644686575863841 0.801227703215143 GO:0098631 cell adhesion mediator activity 2/534 76/18639 0.0263157894736842 0.918539325842697 0.644686575863841 0.801227703215143 GO:0005506 iron ion binding 4/534 154/18639 0.025974025974026 0.906610243688895 0.647222641097507 0.801227703215143 GO:0000287 magnesium ion binding 6/534 230/18639 0.0260869565217391 0.910552027357108 0.648512046882844 0.801227703215143 GO:0000993 RNA polymerase II complex binding 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0005484 SNAP receptor activity 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0045505 dynein intermediate chain binding 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/534 36/18639 0.0277777777777778 0.969569288389513 0.649167649085905 0.801227703215143 GO:0004857 enzyme inhibitor activity 11/534 416/18639 0.0264423076923077 0.922955380293863 0.649409001650306 0.801227703215143 GO:0009055 electron transfer activity 3/534 116/18639 0.0258620689655172 0.902702440914374 0.649884692607838 0.801227703215143 GO:0051540 metal cluster binding 2/534 77/18639 0.025974025974026 0.906610243688895 0.651750469472841 0.802428758584893 GO:0008514 organic anion transmembrane transporter activity 7/534 269/18639 0.0260223048327138 0.908295392840733 0.65438417369379 0.804568267026159 GO:1990782 protein tyrosine kinase binding 3/534 117/18639 0.0256410256410256 0.894987035436474 0.655606217587874 0.804568267026159 GO:0008236 serine-type peptidase activity 5/534 194/18639 0.0257731958762887 0.899600370670682 0.65617011999689 0.804568267026159 GO:0042805 actinin binding 1/534 37/18639 0.027027027027027 0.943364713027634 0.659238308409032 0.807230581725346 GO:0005125 cytokine activity 6/534 234/18639 0.0256410256410256 0.894987035436474 0.664819006941705 0.812738284763097 GO:0016835 carbon-oxygen lyase activity 2/534 79/18639 0.0253164556962025 0.883658085620822 0.665542350967114 0.812738284763097 GO:0017171 serine hydrolase activity 5/534 198/18639 0.0252525252525253 0.881426625808648 0.673667831602961 0.821238808543433 GO:0003689 DNA clamp loader activity 4/534 160/18639 0.025 0.872612359550562 0.676555911972324 0.821238808543433 GO:0004540 RNA nuclease activity 3/534 121/18639 0.0247933884297521 0.865400687157582 0.677818337947924 0.821238808543433 GO:0000217 DNA secondary structure binding 1/534 39/18639 0.0256410256410256 0.894987035436474 0.678522221085422 0.821238808543433 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/534 39/18639 0.0256410256410256 0.894987035436474 0.678522221085422 0.821238808543433 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/534 39/18639 0.0256410256410256 0.894987035436474 0.678522221085422 0.821238808543433 GO:0015101 organic cation transmembrane transporter activity 2/534 81/18639 0.0246913580246914 0.861839367457345 0.678890748395905 0.821238808543433 GO:0015036 disulfide oxidoreductase activity 1/534 40/18639 0.025 0.872612359550562 0.68775174441555 0.82530209329866 GO:0030331 nuclear estrogen receptor binding 1/534 40/18639 0.025 0.872612359550562 0.68775174441555 0.82530209329866 GO:0050997 quaternary ammonium group binding 1/534 40/18639 0.025 0.872612359550562 0.68775174441555 0.82530209329866 GO:0061791 GTPase motor activity 1/534 40/18639 0.025 0.872612359550562 0.68775174441555 0.82530209329866 GO:0071855 neuropeptide receptor binding 1/534 40/18639 0.025 0.872612359550562 0.68775174441555 0.82530209329866 GO:1990606 membrane scission GTPase motor activity 1/534 40/18639 0.025 0.872612359550562 0.68775174441555 0.82530209329866 GO:0005254 chloride channel activity 2/534 83/18639 0.0240963855421687 0.841072153783674 0.691801662207445 0.829056585867777 GO:0140713 histone chaperone activity 4/534 164/18639 0.024390243902439 0.851329131268841 0.695148125528465 0.829424729879673 GO:0005539 glycosaminoglycan binding 6/534 242/18639 0.0247933884297521 0.865400687157582 0.695977235004044 0.829424729879673 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/534 41/18639 0.024390243902439 0.851329131268841 0.696716773098925 0.829424729879673 GO:0017080 sodium channel regulator activity 1/534 41/18639 0.024390243902439 0.851329131268841 0.696716773098925 0.829424729879673 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/534 41/18639 0.024390243902439 0.851329131268841 0.696716773098925 0.829424729879673 GO:0004860 protein kinase inhibitor activity 2/534 84/18639 0.0238095238095238 0.831059390048154 0.69809514222226 0.829698897731896 GO:0008168 methyltransferase activity 5/534 204/18639 0.0245098039215686 0.855502313284864 0.698790849423085 0.829698897731896 GO:0004402 histone acetyltransferase activity 1/534 42/18639 0.0238095238095238 0.831059390048154 0.705424873064791 0.83427383148267 GO:0016859 cis-trans isomerase activity 1/534 42/18639 0.0238095238095238 0.831059390048154 0.705424873064791 0.83427383148267 GO:0019894 kinesin binding 1/534 42/18639 0.0238095238095238 0.831059390048154 0.705424873064791 0.83427383148267 GO:0016874 ligase activity 4/534 167/18639 0.0239520958083832 0.836035793581377 0.7085838117672 0.836445716864762 GO:0004519 endonuclease activity 3/534 127/18639 0.0236220472440945 0.824515615323365 0.709120091075348 0.836445716864762 GO:0050660 flavin adenine dinucleotide binding 2/534 86/18639 0.0232558139534884 0.811732427488895 0.710362665058864 0.836814657791855 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/534 43/18639 0.0232558139534884 0.811732427488895 0.713883394212471 0.839862816720554 GO:0015291 secondary active transmembrane transporter activity 7/534 287/18639 0.024390243902439 0.851329131268841 0.718739751101593 0.843047519339694 GO:0003954 NADH dehydrogenase activity 1/534 44/18639 0.0227272727272727 0.793283963227783 0.722099476568383 0.843047519339694 GO:0016790 thiolester hydrolase activity 1/534 44/18639 0.0227272727272727 0.793283963227783 0.722099476568383 0.843047519339694 GO:0030547 signaling receptor inhibitor activity 1/534 44/18639 0.0227272727272727 0.793283963227783 0.722099476568383 0.843047519339694 GO:0043014 alpha-tubulin binding 1/534 44/18639 0.0227272727272727 0.793283963227783 0.722099476568383 0.843047519339694 GO:0004197 cysteine-type endopeptidase activity 2/534 88/18639 0.0227272727272727 0.793283963227783 0.722210708234337 0.843047519339694 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/534 89/18639 0.0224719101123595 0.784370660270168 0.727979955425188 0.844565617790628 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/534 89/18639 0.0224719101123595 0.784370660270168 0.727979955425188 0.844565617790628 GO:0031072 heat shock protein binding 3/534 131/18639 0.0229007633587786 0.799339566000515 0.728658448984189 0.844565617790628 GO:0008201 heparin binding 4/534 172/18639 0.0232558139534884 0.811732427488895 0.730009738756507 0.844565617790628 GO:0008009 chemokine activity 1/534 45/18639 0.0222222222222222 0.77565543071161 0.730080056267898 0.844565617790628 GO:0046915 transition metal ion transmembrane transporter activity 1/534 45/18639 0.0222222222222222 0.77565543071161 0.730080056267898 0.844565617790628 GO:0051539 4 iron, 4 sulfur cluster binding 1/534 45/18639 0.0222222222222222 0.77565543071161 0.730080056267898 0.844565617790628 GO:0019210 kinase inhibitor activity 2/534 90/18639 0.0222222222222222 0.77565543071161 0.733647424387294 0.846516258908416 GO:0140793 histone H2AXY142 phosphatase activity 2/534 90/18639 0.0222222222222222 0.77565543071161 0.733647424387294 0.846516258908416 GO:0003924 GTPase activity 8/534 331/18639 0.0241691842900302 0.843613157269425 0.735644682795873 0.847733949444668 GO:0030291 protein serine/threonine kinase inhibitor activity 1/534 46/18639 0.0217391304347826 0.758793356130923 0.737831871367013 0.84916711538403 GO:0016741 transferase activity, transferring one-carbon groups 5/534 215/18639 0.0232558139534884 0.811732427488895 0.741302507849426 0.852071848102789 GO:0051087 protein-folding chaperone binding 3/534 134/18639 0.0223880597014925 0.78144390407513 0.742626285429362 0.852504664395951 GO:0005504 fatty acid binding 1/534 47/18639 0.0212765957446809 0.742648816638776 0.745361467488672 0.853440492122723 GO:0061733 protein-lysine-acetyltransferase activity 1/534 47/18639 0.0212765957446809 0.742648816638776 0.745361467488672 0.853440492122723 GO:0004252 serine-type endopeptidase activity 4/534 176/18639 0.0227272727272727 0.793283963227783 0.746286297000648 0.853440492122723 GO:0051213 dioxygenase activity 2/534 93/18639 0.021505376344086 0.75063428778543 0.7500501051957 0.853684557173093 GO:0140789 histone phosphatase activity 3/534 136/18639 0.0220588235294118 0.769952081956378 0.75161669655622 0.853684557173093 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/534 48/18639 0.0208333333333333 0.727176966292135 0.752675203308436 0.853684557173093 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/534 48/18639 0.0208333333333333 0.727176966292135 0.752675203308436 0.853684557173093 GO:0005004 GPI-linked ephrin receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0005008 hepatocyte growth factor receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0005009 insulin receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0005011 macrophage colony-stimulating factor receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0005020 stem cell factor receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0008288 boss receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0036332 placental growth factor receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0038062 protein tyrosine kinase collagen receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0060175 brain-derived neurotrophic factor receptor activity 1/534 49/18639 0.0204081632653061 0.712336620041275 0.759779255884053 0.853684557173093 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/534 181/18639 0.0220994475138122 0.771370041591657 0.765566681188865 0.853974830754998 GO:0016407 acetyltransferase activity 2/534 96/18639 0.0208333333333333 0.727176966292135 0.765576977617824 0.853974830754998 GO:0005006 epidermal growth factor receptor activity 1/534 50/18639 0.02 0.69808988764045 0.766679625833376 0.853974830754998 GO:0005007 fibroblast growth factor receptor activity 1/534 50/18639 0.02 0.69808988764045 0.766679625833376 0.853974830754998 GO:0005017 platelet-derived growth factor receptor activity 1/534 50/18639 0.02 0.69808988764045 0.766679625833376 0.853974830754998 GO:0005019 platelet-derived growth factor beta-receptor activity 1/534 50/18639 0.02 0.69808988764045 0.766679625833376 0.853974830754998 GO:0015605 organophosphate ester transmembrane transporter activity 1/534 50/18639 0.02 0.69808988764045 0.766679625833376 0.853974830754998 GO:0030594 neurotransmitter receptor activity 2/534 97/18639 0.0206185567010309 0.719680296536546 0.770563407269952 0.857196955823194 GO:0005010 insulin-like growth factor receptor activity 1/534 51/18639 0.0196078431372549 0.684401850627891 0.773382142364926 0.857196955823194 GO:0005030 neurotrophin receptor activity 1/534 51/18639 0.0196078431372549 0.684401850627891 0.773382142364926 0.857196955823194 GO:0030544 Hsp70 protein binding 1/534 51/18639 0.0196078431372549 0.684401850627891 0.773382142364926 0.857196955823194 GO:0004725 protein tyrosine phosphatase activity 2/534 98/18639 0.0204081632653061 0.712336620041275 0.775457219858365 0.858439726780478 GO:0008237 metallopeptidase activity 4/534 184/18639 0.0217391304347826 0.758793356130923 0.776576010944747 0.858622125123185 GO:0004864 protein phosphatase inhibitor activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:0005003 ephrin receptor activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:0005005 transmembrane-ephrin receptor activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:0034212 protein N-acetyltransferase activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:0038064 collagen receptor activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/534 53/18639 0.0188679245283019 0.658575365698537 0.786216104147412 0.859777223846506 GO:0008234 cysteine-type peptidase activity 4/534 187/18639 0.0213903743315508 0.746620200684973 0.787173813832801 0.859777223846506 GO:0031406 carboxylic acid binding 4/534 187/18639 0.0213903743315508 0.746620200684973 0.787173813832801 0.859777223846506 GO:0046943 carboxylic acid transmembrane transporter activity 4/534 188/18639 0.0212765957446809 0.742648816638776 0.79061617297532 0.861446193314513 GO:0140597 protein carrier chaperone 4/534 188/18639 0.0212765957446809 0.742648816638776 0.79061617297532 0.861446193314513 GO:0015293 symporter activity 3/534 146/18639 0.0205479452054795 0.717215637986763 0.792837590521979 0.862017470279936 GO:0005342 organic acid transmembrane transporter activity 4/534 189/18639 0.0211640211640212 0.738719457820581 0.794013869846741 0.862017470279936 GO:0043177 organic acid binding 4/534 189/18639 0.0211640211640212 0.738719457820581 0.794013869846741 0.862017470279936 GO:0008374 O-acyltransferase activity 1/534 55/18639 0.0181818181818182 0.634627170582227 0.798324528988161 0.864887357505676 GO:0004722 protein serine/threonine phosphatase activity 2/534 103/18639 0.0194174757281553 0.677757172466456 0.798579326763574 0.864887357505676 GO:0008509 monoatomic anion transmembrane transporter activity 3/534 149/18639 0.0201342281879195 0.702775054671593 0.804038063746675 0.86671568443479 GO:0019212 phosphatase inhibitor activity 1/534 56/18639 0.0178571428571429 0.623294542536116 0.804119551670055 0.86671568443479 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/534 56/18639 0.0178571428571429 0.623294542536116 0.804119551670055 0.86671568443479 GO:0170055 lipid transmembrane transporter activity 1/534 56/18639 0.0178571428571429 0.623294542536116 0.804119551670055 0.86671568443479 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/534 57/18639 0.0175438596491228 0.612359550561798 0.809748360764829 0.871738665895151 GO:0004497 monooxygenase activity 2/534 106/18639 0.0188679245283019 0.658575365698537 0.811418948801053 0.872493493334465 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/534 58/18639 0.0172413793103448 0.601801627276249 0.815215714943689 0.875530004116134 GO:0004843 cysteine-type deubiquitinase activity 2/534 108/18639 0.0185185185185185 0.646379525593009 0.819568426040277 0.879155641759535 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/534 60/18639 0.0166666666666667 0.581741573033708 0.825684417161166 0.884661875529821 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/534 61/18639 0.0163934426229508 0.572204825934795 0.830694617991993 0.888971648267293 GO:0022824 transmitter-gated monoatomic ion channel activity 1/534 63/18639 0.0158730158730159 0.554039593365436 0.840287910367364 0.897104530641314 GO:0022835 transmitter-gated channel activity 1/534 63/18639 0.0158730158730159 0.554039593365436 0.840287910367364 0.897104530641314 GO:0101005 deubiquitinase activity 2/534 115/18639 0.0173913043478261 0.607034684904739 0.845660198528775 0.901770353881395 GO:0015294 solute:monoatomic cation symporter activity 2/534 116/18639 0.0172413793103448 0.601801627276249 0.849094856527388 0.904361385650472 GO:0140097 catalytic activity, acting on DNA 7/534 336/18639 0.0208333333333333 0.727176966292135 0.850681988813708 0.904980839163519 GO:0004518 nuclease activity 4/534 209/18639 0.0191387559808612 0.66802860061287 0.853072517874705 0.906017770396082 GO:0008235 metalloexopeptidase activity 1/534 66/18639 0.0151515151515152 0.528855975485189 0.853670076995419 0.906017770396082 GO:0008173 RNA methyltransferase activity 1/534 67/18639 0.0149253731343284 0.520962602716753 0.857877269096019 0.909410532610621 GO:0003777 microtubule motor activity 1/534 68/18639 0.0147058823529412 0.513301387970919 0.861963718498492 0.910443452905266 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/534 68/18639 0.0147058823529412 0.513301387970919 0.861963718498492 0.910443452905266 GO:0015108 chloride transmembrane transporter activity 2/534 121/18639 0.0165289256198347 0.576933791438388 0.865246665312105 0.910443452905266 GO:0051082 unfolded protein binding 2/534 121/18639 0.0165289256198347 0.576933791438388 0.865246665312105 0.910443452905266 GO:0002039 p53 binding 1/534 69/18639 0.0144927536231884 0.505862237420616 0.865932884096565 0.910443452905266 GO:0008080 N-acetyltransferase activity 1/534 69/18639 0.0144927536231884 0.505862237420616 0.865932884096565 0.910443452905266 GO:0098960 postsynaptic neurotransmitter receptor activity 1/534 69/18639 0.0144927536231884 0.505862237420616 0.865932884096565 0.910443452905266 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/534 70/18639 0.0142857142857143 0.498635634028892 0.869788125878602 0.91342977046761 GO:0019783 ubiquitin-like protein peptidase activity 2/534 127/18639 0.015748031496063 0.549677076882244 0.882530645845003 0.925300443842675 GO:0035064 methylated histone binding 1/534 74/18639 0.0135135135135135 0.471682356513817 0.884133748778994 0.925300443842675 GO:0031490 chromatin DNA binding 2/534 128/18639 0.015625 0.545382724719101 0.885204091276159 0.925300443842675 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/534 128/18639 0.015625 0.545382724719101 0.885204091276159 0.925300443842675 GO:0044183 protein folding chaperone 1/534 75/18639 0.0133333333333333 0.465393258426966 0.887466502786644 0.92658915604174 GO:0140034 methylation-dependent protein binding 1/534 76/18639 0.0131578947368421 0.459269662921348 0.890703568478948 0.928891322863329 GO:1901681 sulfur compound binding 5/534 275/18639 0.0181818181818182 0.634627170582227 0.898325532884864 0.933553458969667 GO:0033293 monocarboxylic acid binding 1/534 79/18639 0.0126582278481013 0.441829042810411 0.899867669122684 0.933553458969667 GO:0033192 calmodulin-dependent protein phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0140791 histone H2AXS140 phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/534 81/18639 0.0123456790123457 0.430919683728672 0.905546855200577 0.933553458969667 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/534 82/18639 0.0121951219512195 0.42566456563442 0.90826471161414 0.934215131945972 GO:0033549 MAP kinase phosphatase activity 1/534 82/18639 0.0121951219512195 0.42566456563442 0.90826471161414 0.934215131945972 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/534 83/18639 0.0120481927710843 0.420536076891837 0.910904504899587 0.935860792705056 GO:0004527 exonuclease activity 1/534 84/18639 0.0119047619047619 0.415529695024077 0.913468473124615 0.936357204797442 GO:0017018 myosin phosphatase activity 1/534 84/18639 0.0119047619047619 0.415529695024077 0.913468473124615 0.936357204797442 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/534 88/18639 0.0113636363636364 0.396641981613892 0.923008653145151 0.945060054414831 GO:0003727 single-stranded RNA binding 1/534 89/18639 0.0112359550561798 0.392185330135084 0.925224888346515 0.946252726718026 GO:0052689 carboxylic ester hydrolase activity 1/534 92/18639 0.0108695652173913 0.379396678065462 0.931498770610486 0.951587847388692 GO:0016410 N-acyltransferase activity 1/534 94/18639 0.0106382978723404 0.371324408319388 0.935386625110284 0.954476148071719 GO:0004175 endopeptidase activity 7/534 405/18639 0.0172839506172839 0.603287557220141 0.947332484831681 0.965571049092314 GO:0015103 inorganic anion transmembrane transporter activity 2/534 165/18639 0.0121212121212121 0.423084780388151 0.952209574777986 0.969444137217407 GO:0019888 protein phosphatase regulator activity 1/534 107/18639 0.00934579439252336 0.326210227869369 0.955811313220278 0.972011504969774 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/534 229/18639 0.0131004366812227 0.457264118541779 0.961664559551711 0.976860162072844 GO:0019208 phosphatase regulator activity 1/534 117/18639 0.00854700854700855 0.298329011812158 0.967016301283643 0.98118903174214 GO:0003697 single-stranded DNA binding 1/534 121/18639 0.00826446280991736 0.288466895719194 0.970658982259328 0.982420870993214 GO:0008528 G protein-coupled peptide receptor activity 1/534 122/18639 0.00819672131147541 0.286102412967397 0.971505083537734 0.982420870993214 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/534 122/18639 0.00819672131147541 0.286102412967397 0.971505083537734 0.982420870993214 GO:0001653 peptide receptor activity 1/534 128/18639 0.0078125 0.272691362359551 0.976094047874004 0.985953583711116 GO:0005179 hormone activity 1/534 132/18639 0.00757575757575758 0.264427987742595 0.978735693970615 0.987513592571248 GO:0140767 enzyme-substrate adaptor activity 1/534 139/18639 0.00719424460431655 0.251111470374262 0.982676788241146 0.990379741788389 GO:0140098 catalytic activity, acting on RNA 5/534 387/18639 0.0129198966408269 0.450962459716053 0.987397321215901 0.994024148875068 GO:0005201 extracellular matrix structural constituent 1/534 168/18639 0.00595238095238095 0.207764847512039 0.992596191592609 0.997640020419275 GO:0003735 structural constituent of ribosome 1/534 175/18639 0.00571428571428571 0.199454253611557 0.993970847520571 0.997640020419275 GO:0043021 ribonucleoprotein complex binding 1/534 177/18639 0.00564971751412429 0.197200533231765 0.994314553684545 0.997640020419275 GO:0003730 mRNA 3'-UTR binding 1/534 262/18639 0.00381679389312977 0.133223261000086 0.999533589170526 0.999935560902378 GO:0045182 translation regulator activity 2/534 356/18639 0.00561797752808989 0.196092665067542 0.999660849108465 0.999935560902378 GO:0030371 translation repressor activity 1/534 329/18639 0.00303951367781155 0.106092688091254 0.999935560902378 0.999935560902378