category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 3/32 37/9376 23.7567567567568 HBB/HBA2/HBA1 8.11624697921316 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/32 50/9376 17.58 HBB/HBA2/HBA1 6.87885310381421 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 4/32 122/9376 9.60655737704918 INSR/CFTR/IRS2/AKT3 5.5993659064372 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 3/32 59/9376 14.8983050847458 INSR/IRS2/AKT3 6.26677368781878 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 3/32 62/9376 14.1774193548387 INSR/IRS2/AKT3 6.09189357258423 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 3/32 86/9376 10.2209302325581 DTNA/CACNB2/DES 5.02701657494555 Organismal Systems Aging hsa04211 Longevity regulating pathway 3/32 90/9376 9.76666666666667 INSR/IRS2/AKT3 4.89030134178973 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 3/32 99/9376 8.87878787878788 DTNA/CACNB2/DES 4.61176787312688 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 3/32 105/9376 8.37142857142857 DTNA/CACNB2/DES 4.44505596302129 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 4/32 212/9376 5.52830188679245 INSR/CNR1/MAGI2/AKT3 3.90260839819188 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 3/32 109/9376 8.06422018348624 INSR/IRS2/AKT3 4.34112315985662 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 3/32 133/9376 6.60902255639098 INSR/IRS2/AKT3 3.81242003293491 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 2/32 47/9376 12.468085106383 INSR/IRS2 4.61228889758784 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 3/32 138/9376 6.3695652173913 INSR/IRS2/AKT3 3.71863796019635 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 3/32 157/9376 5.59872611464968 INSR/IRS2/AKT3 3.40047570511587 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 3/32 166/9376 5.29518072289157 INSR/IRS2/AKT3 3.26738178196366 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 3/32 169/9376 5.20118343195266 IRS2/AKT3/UVRAG 3.22515162683398 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/32 66/9376 8.87878787878788 RORA/HLA-DMA 3.75881323921265 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 2/32 70/9376 8.37142857142857 IRS2/AKT3 3.62254150440501 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/32 70/9376 8.37142857142857 DTNA/HLA-DMA 3.62254150440501 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 2/32 75/9376 7.81333333333333 AKT3/REV3L 3.46672712627746 Organismal Systems Nervous system hsa04721 Synaptic vesicle cycle 2/32 79/9376 7.41772151898734 SYT1/CLTCL1 3.35210188825356 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 2/32 80/9376 7.325 AXL/AKT3 3.32469398966765 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/32 233/9376 3.7725321888412 DTNA/DES/ACTG2 2.50786647621 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 3/32 238/9376 3.69327731092437 INSR/AKT3/RASAL2 2.46285127419144 Organismal Systems Immune system hsa04659 Th17 cell differentiation 2/32 109/9376 5.37614678899083 RORA/HLA-DMA 2.68924123019689 Metabolism Amino acid metabolism hsa00360 Phenylalanine metabolism 1/32 16/9376 18.3125 MAOB 4.05579565708562 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 2/32 110/9376 5.32727272727273 INSR/AKT3 2.67152150623965 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/32 112/9376 5.23214285714286 AKT3/HLA-DMA 2.63672155555815 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 2/32 122/9376 4.80327868852459 IRS2/AKT3 2.47438645770177 Metabolism Metabolism of cofactors and vitamins hsa00770 Pantothenate and CoA biosynthesis 1/32 21/9376 13.952380952381 DPYD 3.47721523066515 Metabolism Amino acid metabolism hsa00340 Histidine metabolism 1/32 22/9376 13.3181818181818 MAOB 3.38495952572438 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 2/32 133/9376 4.40601503759398 AKT3/MAOB 2.31504862589747 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 2/32 134/9376 4.37313432835821 CALD1/ACTG2 2.30142732933241 NA NA hsa04517 IgSF CAM signaling 3/32 299/9376 2.93979933110368 MAGI2/AKT3/CLMP 1.99487388113429 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 3/32 300/9376 2.93 INSR/CACNB2/AKT3 1.98822213830137 Human Diseases Neurodegenerative disease hsa05017 Spinocerebellar ataxia 2/32 144/9376 4.06944444444444 RORA/AKT3 2.17213762256054 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 2/32 149/9376 3.93288590604027 INSR/AKT3 2.11179741986446 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 2/32 154/9376 3.80519480519481 CACNB2/AKT3 2.05402175902616 Metabolism Metabolism of other amino acids hsa00410 beta-Alanine metabolism 1/32 31/9376 9.45161290322581 DPYD 2.75819523604316 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 2/32 158/9376 3.70886075949367 INSR/AKT3 2.00951423093981 Human Diseases Immune disease hsa05310 Asthma 1/32 32/9376 9.15625 HLA-DMA 2.70453941930687 Organismal Systems Environmental adaptation hsa04710 Circadian rhythm 1/32 34/9376 8.61764705882353 RORA 2.60396166627547 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/32 173/9376 3.38728323699422 AKT3/HLA-DMA 1.8546266734086 Metabolism Amino acid metabolism hsa00350 Tyrosine metabolism 1/32 37/9376 7.91891891891892 MAOB 2.467647537623 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 1/32 38/9376 7.71052631578947 INSR 2.4255803171825 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 3/32 362/9376 2.42817679558011 INSR/MAGI2/AKT3 1.62170439402192 Human Diseases Immune disease hsa05330 Allograft rejection 1/32 39/9376 7.51282051282051 HLA-DMA 2.38501956580127 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 2/32 180/9376 3.25555555555556 AKT3/HLA-DMA 1.78806998145258 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/32 181/9376 3.23756906077348 AKT3/HLA-DMA 1.77882851009698 Metabolism Amino acid metabolism hsa00260 Glycine, serine and threonine metabolism 1/32 41/9376 7.14634146341463 MAOB 2.30805239637377 Metabolism Amino acid metabolism hsa00380 Tryptophan metabolism 1/32 42/9376 6.97619047619048 MAOB 2.27148247499776 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/32 44/9376 6.65909090909091 HLA-DMA 2.20181008331132 Environmental Information Processing Membrane transport hsa02010 ABC transporters 1/32 45/9376 6.51111111111111 CFTR 2.16858046727363 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/32 45/9376 6.51111111111111 HLA-DMA 2.16858046727363 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 3/32 388/9376 2.26546391752577 INSR/IRS2/AKT3 1.48980116629843 Organismal Systems Digestive system hsa04973 Carbohydrate digestion and absorption 1/32 48/9376 6.10416666666667 AKT3 2.07465271846572 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 2/32 204/9376 2.87254901960784 TWIST2/AKT3 1.5823788467676 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 2/32 205/9376 2.85853658536585 AKT3/HLA-DMA 1.57446826313005 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/32 205/9376 2.85853658536585 INSR/AKT3 1.57446826313005 Human Diseases Substance dependence hsa05030 Cocaine addiction 1/32 49/9376 5.97959183673469 MAOB 2.04510217415701 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 1/32 50/9376 5.86 MAOB 2.01635862994795 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/32 50/9376 5.86 HLA-DMA 2.01635862994795 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/32 51/9376 5.74509803921569 CFTR 1.98838313164976 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 1/32 52/9376 5.63461538461539 INSR 1.96113933633956 Organismal Systems Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption 1/32 53/9376 5.52830188679245 CLTCL1 1.93459329069587 Genetic Information Processing Replication and repair hsa03460 Fanconi anemia pathway 1/32 54/9376 5.42592592592593 REV3L 1.90871323194539 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/32 54/9376 5.42592592592593 HLA-DMA 1.90871323194539 NA NA hsa04081 Hormone signaling 2/32 219/9376 2.67579908675799 INSR/IRS2 1.46845827936382 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/32 56/9376 5.23214285714286 NAIP 1.85883391966254 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 2/32 224/9376 2.61607142857143 AKT3/HLA-DMA 1.43258621584041 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 2/32 226/9376 2.5929203539823 CFTR/AKT3 1.41850851343363 Metabolism Nucleotide metabolism hsa00240 Pyrimidine metabolism 1/32 59/9376 4.96610169491525 DPYD 1.78832322310926 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/32 59/9376 4.96610169491525 AKT3 1.78832322310926 Environmental Information Processing Signal transduction hsa04370 VEGF signaling pathway 1/32 60/9376 4.88333333333333 AKT3 1.76587422829162 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/32 63/9376 4.65079365079365 PTGIS 1.701402130481 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/32 65/9376 4.50769230769231 AKT3 1.6606351179127 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 2/32 248/9376 2.36290322580645 NAIP/AKT3 1.27290870541894 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/32 68/9376 4.30882352941176 AKT3 1.60248542032542 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 1/32 69/9376 4.2463768115942 AKT3 1.58384554908718 Human Diseases Substance dependence hsa05031 Amphetamine addiction 1/32 69/9376 4.2463768115942 MAOB 1.58384554908718 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 2/32 253/9376 2.31620553359684 NAIP/AKT3 1.24196497388044 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/32 70/9376 4.18571428571429 AKT3 1.56555572767891 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/32 71/9376 4.12676056338028 AKT3 1.54760392975508 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/32 71/9376 4.12676056338028 AKT3 1.54760392975508 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/32 73/9376 4.01369863013699 MAOB 1.51266916028386 Human Diseases Cancer: specific types hsa05218 Melanoma 1/32 73/9376 4.01369863013699 AKT3 1.51266916028386 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/32 73/9376 4.01369863013699 AKT3 1.51266916028386 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/32 76/9376 3.85526315789474 CFTR 1.46253300605476 Human Diseases Cancer: specific types hsa05214 Glioma 1/32 76/9376 3.85526315789474 AKT3 1.46253300605476 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/32 77/9376 3.80519480519481 AKT3 1.44638689154971 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/32 77/9376 3.80519480519481 AKT3 1.44638689154971 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 1/32 78/9376 3.75641025641026 INPP4B 1.43050901852232 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/32 78/9376 3.75641025641026 CLTCL1 1.43050901852232 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/32 78/9376 3.75641025641026 HLA-DMA 1.43050901852232 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/32 82/9376 3.57317073170732 DPYD 1.3695200901449 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/32 82/9376 3.57317073170732 HLA-DMA 1.3695200901449 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/32 86/9376 3.40697674418605 AKT3 1.31222248551542 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 1/32 87/9376 3.36781609195402 CACNB2 1.29842636406601 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/32 87/9376 3.36781609195402 AKT3 1.29842636406601 Organismal Systems Digestive system hsa04976 Bile secretion 1/32 90/9376 3.25555555555556 CFTR 1.25821441366707 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/32 90/9376 3.25555555555556 AKT3 1.25821441366707 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/32 91/9376 3.21978021978022 AKT3 1.24518514727976 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/32 93/9376 3.1505376344086 INSR 1.21965937574999 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/32 93/9376 3.1505376344086 HLA-DMA 1.21965937574999 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/32 93/9376 3.1505376344086 AKT3 1.21965937574999 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/32 95/9376 3.08421052631579 HLA-DMA 1.19481375524036 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 1/32 98/9376 2.98979591836735 INPP4B 1.15874694433376 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/32 98/9376 2.98979591836735 AKT3 1.15874694433376 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/32 99/9376 2.95959595959596 AKT3 1.14702944536745 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/32 99/9376 2.95959595959596 HLA-DMA 1.14702944536745 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/32 99/9376 2.95959595959596 AKT3 1.14702944536745 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/32 100/9376 2.93 HLA-DMA 1.13545820124843 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 1/32 101/9376 2.9009900990099 AKT3 1.12402972196865 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/32 102/9376 2.87254901960784 CFTR 1.11274063546937 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/32 103/9376 2.84466019417476 AKT3 1.10158768252671 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 1/32 105/9376 2.79047619047619 AKT3 1.07967767577261 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/32 106/9376 2.76415094339623 AKT3 1.06891462533072 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 1/32 107/9376 2.73831775700935 AKT3 1.05827570669749 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/32 109/9376 2.68807339449541 AKT3 1.03735930053717 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/32 110/9376 2.66363636363636 AKT3 1.02707654546609 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/32 115/9376 2.54782608695652 AKT3 0.977319023767324 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/32 115/9376 2.54782608695652 MAOB 0.977319023767324 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/32 119/9376 2.46218487394958 AKT3 0.939366024206937 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 1/32 120/9376 2.44166666666667 AKT3 0.930117936862081 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/32 122/9376 2.4016393442623 AKT3 0.911896733334058 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/32 122/9376 2.4016393442623 AKT3 0.911896733334058 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/32 125/9376 2.344 AKT3 0.885225971668205 Organismal Systems Immune system hsa04611 Platelet activation 1/32 126/9376 2.32539682539683 AKT3 0.876505296349462 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/32 130/9376 2.25384615384615 AKT3 0.842428781721512 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 2/32 370/9376 1.58378378378378 CNR1/P2RY14 0.670472748067814 Human Diseases Infectious disease: viral hsa05162 Measles 1/32 136/9376 2.15441176470588 AKT3 0.793575817359962 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/32 137/9376 2.13868613138686 AKT3 0.785680625337013 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/32 138/9376 2.1231884057971 AKT3 0.777852744710438 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/32 139/9376 2.10791366906475 AKT3 0.770091023977777 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/32 140/9376 2.09285714285714 AKT3 0.762394339794082 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/32 142/9376 2.06338028169014 AKT3 0.74719172318703 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/32 142/9376 2.06338028169014 AKT3 0.74719172318703 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/32 143/9376 2.04895104895105 HLA-DMA 0.739683677037843 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/32 144/9376 2.03472222222222 AKT3 0.732236438374481 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/32 144/9376 2.03472222222222 AKT3 0.732236438374481 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/32 148/9376 1.97972972972973 AKT3 0.703035999687594 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/32 149/9376 1.96644295302013 CNR1 0.695878325996527 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/32 150/9376 1.95333333333333 AKT3 0.688775824444307 NA NA hsa04518 Integrin signaling 1/32 154/9376 1.9025974025974 AKT3 0.660900519686657 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/32 154/9376 1.9025974025974 CACNB2 0.660900519686657 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/32 155/9376 1.89032258064516 HLA-DMA 0.654061278248361 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/32 156/9376 1.87820512820513 AKT3 0.647272297216901 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/32 157/9376 1.86624203821656 AXL 0.640532819800219 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/32 157/9376 1.86624203821656 AKT3 0.640532819800219 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/32 160/9376 1.83125 HLA-DMA 0.620604083803487 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/32 163/9376 1.79754601226994 AKT3 0.601095154384076 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/32 168/9376 1.74404761904762 AKT3 0.569464858822384 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/32 170/9376 1.72352941176471 CFTR 0.557107978230086 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/32 170/9376 1.72352941176471 AKT3 0.557107978230086 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/32 178/9376 1.64606741573034 ROR2 0.509255055516704 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/32 187/9376 1.5668449197861 NAIP 0.458189517045621 Human Diseases Substance dependence hsa05034 Alcoholism 1/32 191/9376 1.53403141361257 MAOB 0.436353154863063 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/32 193/9376 1.51813471502591 AKT3 0.425621213696174 Cellular Processes Cell motility hsa04814 Motor proteins 1/32 194/9376 1.51030927835052 ACTG2 0.420300491522045 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/32 195/9376 1.5025641025641 AKT3 0.415009452709336 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/32 196/9376 1.49489795918367 AKT3 0.409747743399963 NA NA hsa04082 Neuroactive ligand signaling 1/32 199/9376 1.47236180904523 P2RY14 0.394135144474645 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/32 200/9376 1.465 NAIP 0.388987334414234 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/32 201/9376 1.45771144278607 WT1 0.383867173277149 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/32 203/9376 1.44334975369458 AKT3 0.373708525999383 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/32 214/9376 1.36915887850467 AKT3 0.319682802180065 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/32 216/9376 1.35648148148148 AKT3 0.310177524250364 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/32 217/9376 1.35023041474654 AKT3 0.305459691161649 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/32 227/9376 1.29074889867841 AKT3 0.259500623477347 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/32 227/9376 1.29074889867841 AKT3 0.259500623477347 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 1/32 232/9376 1.26293103448276 AKT3 0.237307763498156 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/32 235/9376 1.2468085106383 CNR1 0.224228814303886 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/32 250/9376 1.172 CLTCL1 0.161306709276718 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/32 250/9376 1.172 CLTCL1 0.161306709276718 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/32 268/9376 1.09328358208955 MAOB 0.0906682666446575 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/32 308/9376 0.951298701298701 CLTCL1 -0.0508574238574818 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/32 323/9376 0.907120743034056 IRS2 -0.0994072239505269 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/32 333/9376 0.87987987987988 AKT3 -0.130609817202466 NA NA hsa04519 Cadherin signaling 1/32 404/9376 0.725247524752475 DES -0.330355754516904