ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031720 haptoglobin binding 3/58 10/18639 0.3 96.4086206896552 3.37862369150263e-06 0.000969664999461255 GO:0005344 oxygen carrier activity 3/58 14/18639 0.214285714285714 68.8633004926108 1.01581350081297e-05 0.00145769237366661 GO:0043548 phosphatidylinositol 3-kinase binding 3/58 26/18639 0.115384615384615 37.0802387267905 7.06574294473947e-05 0.00675956075046742 GO:0019825 oxygen binding 3/58 34/18639 0.0882352941176471 28.355476673428 0.00015977135414741 0.00717248538880373 GO:0005004 GPI-linked ephrin receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0005008 hepatocyte growth factor receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0005009 insulin receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0005011 macrophage colony-stimulating factor receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0005020 stem cell factor receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0008288 boss receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0036332 placental growth factor receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0038062 protein tyrosine kinase collagen receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0060175 brain-derived neurotrophic factor receptor activity 3/58 49/18639 0.0612244897959184 19.6752287121745 0.000475898772828306 0.00717248538880373 GO:0005006 epidermal growth factor receptor activity 3/58 50/18639 0.06 19.281724137931 0.000505160200914847 0.00717248538880373 GO:0005007 fibroblast growth factor receptor activity 3/58 50/18639 0.06 19.281724137931 0.000505160200914847 0.00717248538880373 GO:0005017 platelet-derived growth factor receptor activity 3/58 50/18639 0.06 19.281724137931 0.000505160200914847 0.00717248538880373 GO:0005019 platelet-derived growth factor beta-receptor activity 3/58 50/18639 0.06 19.281724137931 0.000505160200914847 0.00717248538880373 GO:0005010 insulin-like growth factor receptor activity 3/58 51/18639 0.0588235294117647 18.9036511156187 0.000535550670869971 0.00717248538880373 GO:0005021 vascular endothelial growth factor receptor activity 3/58 51/18639 0.0588235294117647 18.9036511156187 0.000535550670869971 0.00717248538880373 GO:0005030 neurotrophin receptor activity 3/58 51/18639 0.0588235294117647 18.9036511156187 0.000535550670869971 0.00717248538880373 GO:0005003 ephrin receptor activity 3/58 53/18639 0.0566037735849057 18.190305790501 0.000599789718924354 0.00717248538880373 GO:0005005 transmembrane-ephrin receptor activity 3/58 53/18639 0.0566037735849057 18.190305790501 0.000599789718924354 0.00717248538880373 GO:0038064 collagen receptor activity 3/58 53/18639 0.0566037735849057 18.190305790501 0.000599789718924354 0.00717248538880373 GO:0004601 peroxidase activity 3/58 57/18639 0.0526315789473684 16.9137931034483 0.000742586609155844 0.00852489427310909 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/58 59/18639 0.0508474576271186 16.3404441846873 0.000821415694540912 0.00906716555127853 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/58 60/18639 0.05 16.0681034482759 0.000862745788951508 0.00917066820107715 GO:0020037 heme binding 4/58 142/18639 0.028169014084507 9.05245264691598 0.000995795603865206 0.0102069049396184 GO:0016500 protein-hormone receptor activity 3/58 67/18639 0.0447761194029851 14.3893463715903 0.00118929851736851 0.011769954292578 GO:0046906 tetrapyrrole binding 4/58 152/18639 0.0263157894736842 8.45689655172414 0.00128120987262354 0.0122569077814319 GO:0034987 immunoglobulin receptor binding 2/58 19/18639 0.105263157894737 33.8275862068966 0.00157288785404059 0.0145618972293436 GO:0019199 transmembrane receptor protein kinase activity 3/58 78/18639 0.0384615384615385 12.3600795755968 0.00184353364765769 0.0165341924024299 GO:0003823 antigen binding 4/58 174/18639 0.0229885057471264 7.38763376932224 0.00210217763853017 0.0182825752199442 GO:0016209 antioxidant activity 3/58 86/18639 0.0348837209302326 11.2103047313553 0.0024367773855435 0.0205692679309113 GO:0071889 14-3-3 protein binding 2/58 33/18639 0.0606060606060606 19.4764890282132 0.00472285554685445 0.0387274154842065 GO:0035401 histone H3Y41 kinase activity 3/58 115/18639 0.0260869565217391 8.38335832083958 0.00551683292702541 0.04230725785302 GO:0140801 histone H2AXY142 kinase activity 3/58 115/18639 0.0260869565217391 8.38335832083958 0.00551683292702541 0.04230725785302 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/58 36/18639 0.0555555555555556 17.8534482758621 0.00560165783419777 0.04230725785302 GO:0140104 molecular carrier activity 4/58 249/18639 0.0160642570281124 5.16244287494807 0.00750178862687523 0.0542771124878518 GO:0035198 miRNA binding 2/58 42/18639 0.0476190476190476 15.3029556650246 0.00756475435370756 0.0542771124878518 GO:0051539 4 iron, 4 sulfur cluster binding 2/58 45/18639 0.0444444444444444 14.2827586206897 0.00864643821774821 0.0605250675242375 GO:0030276 clathrin binding 2/58 46/18639 0.0434782608695652 13.972263868066 0.00902151686617343 0.0616470319188518 GO:0004713 protein tyrosine kinase activity 3/58 140/18639 0.0214285714285714 6.88633004926108 0.00946899868480248 0.0632000609892631 GO:0140693 molecular condensate scaffold activity 2/58 48/18639 0.0416666666666667 13.3900862068966 0.00979316829252715 0.0638781659080748 GO:0030159 signaling receptor complex adaptor activity 2/58 52/18639 0.0384615384615385 12.3600795755968 0.0114211469724639 0.0728415373577141 GO:0005506 iron ion binding 3/58 154/18639 0.0194805194805195 6.2603000447828 0.0122484798469793 0.0749664673910319 GO:0140463 chromatin-protein adaptor activity 2/58 54/18639 0.037037037037037 11.9022988505747 0.0122767385622944 0.0749664673910319 GO:0061980 regulatory RNA binding 2/58 58/18639 0.0344827586206897 11.0814506539834 0.014069312119022 0.0841227620449859 GO:0001786 phosphatidylserine binding 2/58 59/18639 0.0338983050847458 10.8936294564582 0.0145341505900565 0.0851285963131878 GO:0017022 myosin binding 2/58 76/18639 0.0263157894736842 8.45689655172414 0.0234092546829086 0.131598217336215 GO:0051536 iron-sulfur cluster binding 2/58 76/18639 0.0263157894736842 8.45689655172414 0.0234092546829086 0.131598217336215 GO:0051540 metal cluster binding 2/58 77/18639 0.025974025974026 8.34706672637707 0.023986127363807 0.131598217336215 GO:0141003 histone H2AX kinase activity 4/58 354/18639 0.0112994350282486 3.6312098188194 0.0243021098216704 0.131598217336215 GO:0140996 histone H3 kinase activity 4/58 357/18639 0.0112044817927171 3.60069545059403 0.0249695498015886 0.132708533204739 GO:0035173 histone kinase activity 4/58 360/18639 0.0111111111111111 3.57068965517241 0.0256480547633114 0.133836213037643 GO:0030165 PDZ domain binding 2/58 83/18639 0.0240963855421687 7.7436643124221 0.0275683225106986 0.141287652867331 GO:0050660 flavin adenine dinucleotide binding 2/58 86/18639 0.0232558139534884 7.47353648757017 0.0294353819072786 0.146813495628394 GO:0008239 dipeptidyl-peptidase activity 1/58 10/18639 0.1 32.1362068965517 0.0306927168561103 0.146813495628394 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/58 10/18639 0.1 32.1362068965517 0.0306927168561103 0.146813495628394 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/58 10/18639 0.1 32.1362068965517 0.0306927168561103 0.146813495628394 GO:0072341 modified amino acid binding 2/58 91/18639 0.021978021978022 7.06290261462675 0.0326560199034607 0.15364389692284 GO:0070697 activin receptor binding 1/58 11/18639 0.0909090909090909 29.2147335423197 0.0337105826794152 0.156047374661164 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/58 12/18639 0.0833333333333333 26.7801724137931 0.0367192141054725 0.167276419813819 GO:0031994 insulin-like growth factor I binding 1/58 13/18639 0.0769230769230769 24.7201591511936 0.0397186388964685 0.171764864612269 GO:0043560 insulin receptor substrate binding 1/58 13/18639 0.0769230769230769 24.7201591511936 0.0397186388964685 0.171764864612269 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/58 13/18639 0.0769230769230769 24.7201591511936 0.0397186388964685 0.171764864612269 GO:0008191 metalloendopeptidase inhibitor activity 1/58 14/18639 0.0714285714285714 22.9544334975369 0.042708884732612 0.171764864612269 GO:0008331 high voltage-gated calcium channel activity 1/58 14/18639 0.0714285714285714 22.9544334975369 0.042708884732612 0.171764864612269 GO:0032036 myosin heavy chain binding 1/58 14/18639 0.0714285714285714 22.9544334975369 0.042708884732612 0.171764864612269 GO:0046030 inositol trisphosphate phosphatase activity 1/58 14/18639 0.0714285714285714 22.9544334975369 0.042708884732612 0.171764864612269 GO:0070742 C2H2 zinc finger domain binding 1/58 14/18639 0.0714285714285714 22.9544334975369 0.042708884732612 0.171764864612269 GO:0000149 SNARE binding 2/58 106/18639 0.0188679245283019 6.06343526350033 0.043090837115273 0.171764864612269 GO:0005523 tropomyosin binding 1/58 15/18639 0.0666666666666667 21.4241379310345 0.0456899792123707 0.174574745096597 GO:0017081 chloride channel regulator activity 1/58 15/18639 0.0666666666666667 21.4241379310345 0.0456899792123707 0.174574745096597 GO:0120283 protein serine/threonine kinase binding 1/58 15/18639 0.0666666666666667 21.4241379310345 0.0456899792123707 0.174574745096597 GO:0005159 insulin-like growth factor receptor binding 1/58 16/18639 0.0625 20.0851293103448 0.04866194985271 0.174574745096597 GO:0008142 oxysterol binding 1/58 16/18639 0.0625 20.0851293103448 0.04866194985271 0.174574745096597 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/58 16/18639 0.0625 20.0851293103448 0.04866194985271 0.174574745096597 GO:0022841 potassium ion leak channel activity 1/58 16/18639 0.0625 20.0851293103448 0.04866194985271 0.174574745096597 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/58 16/18639 0.0625 20.0851293103448 0.04866194985271 0.174574745096597 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/58 17/18639 0.0588235294117647 18.9036511156187 0.0516248240893284 0.182917586588114 GO:0017075 syntaxin-1 binding 1/58 18/18639 0.0555555555555556 17.8534482758621 0.0545786292768928 0.188723694005641 GO:0031690 adrenergic receptor binding 1/58 18/18639 0.0555555555555556 17.8534482758621 0.0545786292768928 0.188723694005641 GO:0005520 insulin-like growth factor binding 1/58 19/18639 0.0526315789473684 16.9137931034483 0.0575233926892732 0.19196760118397 GO:0022840 leak channel activity 1/58 19/18639 0.0526315789473684 16.9137931034483 0.0575233926892732 0.19196760118397 GO:0022842 narrow pore channel activity 1/58 19/18639 0.0526315789473684 16.9137931034483 0.0575233926892732 0.19196760118397 GO:0001614 purinergic nucleotide receptor activity 1/58 20/18639 0.05 16.0681034482759 0.0604591415197792 0.19275482673408 GO:0016502 nucleotide receptor activity 1/58 20/18639 0.05 16.0681034482759 0.0604591415197792 0.19275482673408 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/58 20/18639 0.05 16.0681034482759 0.0604591415197792 0.19275482673408 GO:0052745 inositol phosphate phosphatase activity 1/58 20/18639 0.05 16.0681034482759 0.0604591415197792 0.19275482673408 GO:0035591 signaling adaptor activity 2/58 129/18639 0.0155038759689922 4.98235765838011 0.0611173840864157 0.19275482673408 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/58 21/18639 0.0476190476190476 15.3029556650246 0.0633859028813912 0.19561025942967 GO:0061891 calcium ion sensor activity 1/58 21/18639 0.0476190476190476 15.3029556650246 0.0633859028813912 0.19561025942967 GO:0001664 G protein-coupled receptor binding 3/58 297/18639 0.0101010101010101 3.24608150470219 0.065140516852786 0.198886471667549 GO:0140784 metal ion sensor activity 1/58 22/18639 0.0454545454545455 14.6073667711599 0.0663037038069944 0.200306978869551 GO:0019838 growth factor binding 2/58 136/18639 0.0147058823529412 4.72591277890467 0.0670372689816824 0.200413502059821 GO:0003887 DNA-directed DNA polymerase activity 1/58 23/18639 0.0434782608695652 13.972263868066 0.069212571249611 0.202693958659575 GO:0005158 insulin receptor binding 1/58 23/18639 0.0434782608695652 13.972263868066 0.069212571249611 0.202693958659575 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/58 24/18639 0.0416666666666667 13.3900862068966 0.0721125320826321 0.209053502098136 GO:0022843 voltage-gated monoatomic cation channel activity 2/58 143/18639 0.013986013986014 4.49457439112611 0.0731402402343779 0.209912489472664 GO:0015271 outward rectifier potassium channel activity 1/58 25/18639 0.04 12.8544827586207 0.0750036131000488 0.213129078809049 GO:0022836 gated channel activity 3/58 318/18639 0.00943396226415094 3.03171763175016 0.0765045649147577 0.215262844417014 GO:0050750 low-density lipoprotein particle receptor binding 1/58 26/18639 0.0384615384615385 12.3600795755968 0.0778858410166811 0.217021712347451 GO:0023026 MHC class II protein complex binding 1/58 27/18639 0.037037037037037 11.9022988505747 0.0807592424684103 0.220741929413655 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/58 27/18639 0.037037037037037 11.9022988505747 0.0807592424684103 0.220741929413655 GO:0005242 inward rectifier potassium channel activity 1/58 28/18639 0.0357142857142857 11.4772167487685 0.0836238440124047 0.22641550218453 GO:0099106 ion channel regulator activity 2/58 160/18639 0.0125 4.01702586206897 0.0886611481122901 0.233781979586411 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/58 30/18639 0.0333333333333333 10.7120689655172 0.0893267532136828 0.233781979586411 GO:0033612 receptor serine/threonine kinase binding 1/58 30/18639 0.0333333333333333 10.7120689655172 0.0893267532136828 0.233781979586411 GO:0004866 endopeptidase inhibitor activity 2/58 161/18639 0.0124223602484472 3.99207539087599 0.0896028493188336 0.233781979586411 GO:0017147 Wnt-protein binding 1/58 31/18639 0.032258064516129 10.3665183537264 0.0921651135938002 0.236173103584113 GO:0070325 lipoprotein particle receptor binding 1/58 31/18639 0.032258064516129 10.3665183537264 0.0921651135938002 0.236173103584113 GO:0015106 bicarbonate transmembrane transporter activity 1/58 32/18639 0.03125 10.0425646551724 0.0949947795123062 0.23886806308345 GO:0005201 extracellular matrix structural constituent 2/58 168/18639 0.0119047619047619 3.82573891625616 0.0962776387324876 0.23886806308345 GO:0016247 channel regulator activity 2/58 168/18639 0.0119047619047619 3.82573891625616 0.0962776387324876 0.23886806308345 GO:0030414 peptidase inhibitor activity 2/58 169/18639 0.0118343195266272 3.80310140787594 0.0972427001350308 0.23886806308345 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/58 33/18639 0.0303030303030303 9.73824451410658 0.0978157771362266 0.23886806308345 GO:0141108 transporter regulator activity 2/58 170/18639 0.0117647058823529 3.78073022312373 0.0982105625221152 0.23886806308345 GO:0016831 carboxy-lyase activity 1/58 34/18639 0.0294117647058824 9.45182555780933 0.100628132555237 0.239871981603057 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/58 34/18639 0.0294117647058824 9.45182555780933 0.100628132555237 0.239871981603057 GO:0005244 voltage-gated monoatomic ion channel activity 2/58 173/18639 0.0115606936416185 3.71516842734702 0.10113069607655 0.239871981603057 GO:0022832 voltage-gated channel activity 2/58 175/18639 0.0114285714285714 3.67270935960591 0.103090983186291 0.241341034157731 GO:0034061 DNA polymerase activity 1/58 35/18639 0.0285714285714286 9.18177339901478 0.103431871781885 0.241341034157731 GO:0016853 isomerase activity 2/58 180/18639 0.0111111111111111 3.57068965517241 0.108037580747072 0.250054723180723 GO:0023023 MHC protein complex binding 1/58 37/18639 0.027027027027027 8.68546132339236 0.109013605324006 0.250295237823917 GO:0061135 endopeptidase regulator activity 2/58 184/18639 0.0108695652173913 3.49306596701649 0.112040403938862 0.255203142305186 GO:0015276 ligand-gated monoatomic ion channel activity 2/58 186/18639 0.010752688172043 3.45550611790879 0.114056457663172 0.257749632671892 GO:0022834 ligand-gated channel activity 2/58 188/18639 0.0106382978723404 3.41874541452678 0.116082015456819 0.260277644032086 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/58 40/18639 0.025 8.03405172413793 0.117322230098246 0.260765742263236 GO:0019902 phosphatase binding 2/58 190/18639 0.0105263157894737 3.38275862068966 0.118116886739445 0.260765742263236 GO:0017080 sodium channel regulator activity 1/58 41/18639 0.024390243902439 7.8380992430614 0.120074814143319 0.263064669153683 GO:0048487 beta-tubulin binding 1/58 42/18639 0.0238095238095238 7.65147783251231 0.122818961943065 0.267038197558029 GO:0005245 voltage-gated calcium channel activity 1/58 43/18639 0.0232558139534884 7.47353648757017 0.125554698901032 0.268911929735793 GO:0008200 ion channel inhibitor activity 1/58 43/18639 0.0232558139534884 7.47353648757017 0.125554698901032 0.268911929735793 GO:0001223 transcription coactivator binding 1/58 44/18639 0.0227272727272727 7.30368338557994 0.12828205034563 0.269035076051029 GO:0016248 channel inhibitor activity 1/58 44/18639 0.0227272727272727 7.30368338557994 0.12828205034563 0.269035076051029 GO:0016829 lyase activity 2/58 200/18639 0.01 3.21362068965517 0.128424409125404 0.269035076051029 GO:0042605 peptide antigen binding 1/58 45/18639 0.0222222222222222 7.14137931034483 0.131001041530354 0.270484164886414 GO:0141110 transporter inhibitor activity 1/58 45/18639 0.0222222222222222 7.14137931034483 0.131001041530354 0.270484164886414 GO:0005516 calmodulin binding 2/58 207/18639 0.00966183574879227 3.10494752623688 0.135763166349386 0.2757100743618 GO:0099095 ligand-gated monoatomic anion channel activity 1/58 47/18639 0.0212765957446809 6.83749082905356 0.136414043760891 0.2757100743618 GO:0140359 ABC-type transporter activity 1/58 47/18639 0.0212765957446809 6.83749082905356 0.136414043760891 0.2757100743618 GO:0001222 transcription corepressor binding 1/58 49/18639 0.0204081632653061 6.55840957072484 0.141793906130538 0.284579378038212 GO:0016830 carbon-carbon lyase activity 1/58 51/18639 0.0196078431372549 6.30121703853955 0.147140827992396 0.293259844679288 GO:0005544 calcium-dependent phospholipid binding 1/58 53/18639 0.0188679245283019 6.06343526350033 0.152455007521644 0.297650252780352 GO:0016860 intramolecular oxidoreductase activity 1/58 53/18639 0.0188679245283019 6.06343526350033 0.152455007521644 0.297650252780352 GO:0017046 peptide hormone binding 1/58 53/18639 0.0188679245283019 6.06343526350033 0.152455007521644 0.297650252780352 GO:0050661 NADP binding 1/58 54/18639 0.0185185185185185 5.95114942528736 0.155099880520877 0.300735793795821 GO:0061134 peptidase regulator activity 2/58 226/18639 0.00884955752212389 2.84391211473909 0.15613112639574 0.300735793795821 GO:0098632 cell-cell adhesion mediator activity 1/58 55/18639 0.0181818181818182 5.84294670846395 0.157736641722372 0.301802774495472 GO:0030170 pyridoxal phosphate binding 1/58 56/18639 0.0178571428571429 5.73860837438424 0.160365315569773 0.304800301778311 GO:0070279 vitamin B6 binding 1/58 57/18639 0.0175438596491228 5.63793103448276 0.162985926434378 0.305812241661352 GO:0005216 monoatomic ion channel activity 3/58 448/18639 0.00669642857142857 2.15197814039409 0.163028825694031 0.305812241661352 GO:0004879 nuclear receptor activity 1/58 59/18639 0.0169491525423729 5.44681472822911 0.168203056339923 0.312971198531568 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/58 60/18639 0.0166666666666667 5.35603448275862 0.17079962376362 0.312971198531568 GO:0098531 ligand-modulated transcription factor activity 1/58 60/18639 0.0166666666666667 5.35603448275862 0.17079962376362 0.312971198531568 GO:0015026 coreceptor activity 1/58 61/18639 0.0163934426229508 5.26823063877897 0.173388224970451 0.312971198531568 GO:0016836 hydro-lyase activity 1/58 61/18639 0.0163934426229508 5.26823063877897 0.173388224970451 0.312971198531568 GO:0019905 syntaxin binding 1/58 61/18639 0.0163934426229508 5.26823063877897 0.173388224970451 0.312971198531568 GO:0042277 peptide binding 2/58 249/18639 0.00803212851405622 2.58122143747403 0.181505821814626 0.325576067879985 GO:0038024 cargo receptor activity 1/58 65/18639 0.0153846153846154 4.94403183023873 0.183663446818176 0.327400057371531 GO:0050840 extracellular matrix binding 1/58 67/18639 0.0149253731343284 4.79644879053011 0.188753881404098 0.334397308413432 GO:0032934 sterol binding 1/58 68/18639 0.0147058823529412 4.72591277890467 0.191287387481987 0.336806627038836 GO:0140299 molecular sensor activity 1/58 71/18639 0.0140845070422535 4.52622632345799 0.198841342879534 0.347972350039185 GO:0005518 collagen binding 1/58 72/18639 0.0138888888888889 4.46336206896552 0.201343885001087 0.350216333304921 GO:0003725 double-stranded RNA binding 1/58 75/18639 0.0133333333333333 4.2848275862069 0.208805507721634 0.361007112747644 GO:0098631 cell adhesion mediator activity 1/58 76/18639 0.0131578947368421 4.22844827586207 0.21127745776215 0.36309359507627 GO:0016835 carbon-oxygen lyase activity 1/58 79/18639 0.0126582278481013 4.06787429070275 0.218647856834539 0.371313224328478 GO:0046332 SMAD binding 1/58 79/18639 0.0126582278481013 4.06787429070275 0.218647856834539 0.371313224328478 GO:0048306 calcium-dependent protein binding 1/58 80/18639 0.0125 4.01702586206897 0.221089582281931 0.372398568166706 GO:0001618 virus receptor activity 1/58 81/18639 0.0123456790123457 3.96743295019157 0.22352380849173 0.372398568166706 GO:0030971 receptor tyrosine kinase binding 1/58 81/18639 0.0123456790123457 3.96743295019157 0.22352380849173 0.372398568166706 GO:0019207 kinase regulator activity 2/58 287/18639 0.00696864111498258 2.23945692658897 0.224600911728885 0.372398568166706 GO:0140272 exogenous protein binding 1/58 82/18639 0.0121951219512195 3.9190496215307 0.225950558093383 0.372398568166706 GO:0001540 amyloid-beta binding 1/58 83/18639 0.0120481927710843 3.87183215621105 0.228369853649269 0.372398568166706 GO:0005254 chloride channel activity 1/58 83/18639 0.0120481927710843 3.87183215621105 0.228369853649269 0.372398568166706 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/58 86/18639 0.0116279069767442 3.73676824378508 0.235583240664155 0.381990904353744 GO:0042562 hormone binding 1/58 94/18639 0.0106382978723404 3.41874541452678 0.254496524029825 0.410339901104269 GO:0004867 serine-type endopeptidase inhibitor activity 1/58 95/18639 0.0105263157894737 3.38275862068966 0.25682810675327 0.411785847140717 GO:0005249 voltage-gated potassium channel activity 1/58 98/18639 0.0102040816326531 3.27920478536242 0.263779940932913 0.418258801368763 GO:0042626 ATPase-coupled transmembrane transporter activity 1/58 98/18639 0.0102040816326531 3.27920478536242 0.263779940932913 0.418258801368763 GO:0008238 exopeptidase activity 1/58 102/18639 0.00980392156862745 3.15060851926978 0.272949724372753 0.430420719203187 GO:0005253 monoatomic anion channel activity 1/58 103/18639 0.00970873786407767 3.12002008704386 0.275224575534557 0.431636356166219 GO:0045296 cadherin binding 2/58 334/18639 0.00598802395209581 1.92432376626058 0.278838499881613 0.432813252489092 GO:0140097 catalytic activity, acting on DNA 2/58 336/18639 0.00595238095238095 1.91286945812808 0.281151135039473 0.432813252489092 GO:0004497 monooxygenase activity 1/58 106/18639 0.00943396226415094 3.03171763175016 0.282007241168851 0.432813252489092 GO:0008013 beta-catenin binding 1/58 106/18639 0.00943396226415094 3.03171763175016 0.282007241168851 0.432813252489092 GO:0005496 steroid binding 1/58 108/18639 0.00925925925925926 2.97557471264368 0.28649432228532 0.435709807164472 GO:0005261 monoatomic cation channel activity 2/58 341/18639 0.00586510263929619 1.88482151885934 0.286930848620506 0.435709807164472 GO:1902936 phosphatidylinositol bisphosphate binding 1/58 111/18639 0.00900900900900901 2.89515377446412 0.293173318333558 0.442846012430165 GO:0005200 structural constituent of cytoskeleton 1/58 112/18639 0.00892857142857143 2.86930418719212 0.295385966624612 0.443852211629653 GO:0001221 transcription coregulator binding 1/58 115/18639 0.00869565217391304 2.79445277361319 0.301983149264038 0.449063025071393 GO:0017124 SH3 domain binding 1/58 115/18639 0.00869565217391304 2.79445277361319 0.301983149264038 0.449063025071393 GO:0009055 electron transfer activity 1/58 116/18639 0.00862068965517241 2.77036266349584 0.304168691120154 0.449981517275691 GO:1990782 protein tyrosine kinase binding 1/58 117/18639 0.00854700854700855 2.74668435013263 0.306347507506 0.450880690534472 GO:0003697 single-stranded DNA binding 1/58 121/18639 0.00826446280991736 2.65588486748361 0.314995924121976 0.458902691487345 GO:0015108 chloride transmembrane transporter activity 1/58 121/18639 0.00826446280991736 2.65588486748361 0.314995924121976 0.458902691487345 GO:0005267 potassium channel activity 1/58 124/18639 0.00806451612903226 2.59162958843159 0.321412609509097 0.465885954187428 GO:0005525 GTP binding 2/58 378/18639 0.00529100529100529 1.70032840722496 0.329506215588503 0.475217506904022 GO:0005262 calcium channel activity 1/58 131/18639 0.00763358778625954 2.45314556462227 0.33615604043554 0.482383918025 GO:0051087 protein-folding chaperone binding 1/58 134/18639 0.00746268656716418 2.39822439526505 0.342377860745249 0.485091412208193 GO:0002020 protease binding 1/58 136/18639 0.00735294117647059 2.36295638945233 0.346493865862995 0.485091412208193 GO:0016779 nucleotidyltransferase activity 1/58 136/18639 0.00735294117647059 2.36295638945233 0.346493865862995 0.485091412208193 GO:0044325 transmembrane transporter binding 1/58 136/18639 0.00735294117647059 2.36295638945233 0.346493865862995 0.485091412208193 GO:0099094 ligand-gated monoatomic cation channel activity 1/58 136/18639 0.00735294117647059 2.36295638945233 0.346493865862995 0.485091412208193 GO:0030295 protein kinase activator activity 1/58 139/18639 0.00719424460431655 2.31195733068717 0.352620445808038 0.489192678833067 GO:0019001 guanyl nucleotide binding 2/58 400/18639 0.005 1.60681034482759 0.354536854345916 0.489192678833067 GO:0032561 guanyl ribonucleotide binding 2/58 400/18639 0.005 1.60681034482759 0.354536854345916 0.489192678833067 GO:0019903 protein phosphatase binding 1/58 144/18639 0.00694444444444444 2.23168103448276 0.362706209089285 0.491566220400282 GO:0015085 calcium ion transmembrane transporter activity 1/58 147/18639 0.00680272108843537 2.18613652357495 0.368683375641575 0.491566220400282 GO:0019209 kinase activator activity 1/58 148/18639 0.00675675675675676 2.17136533084809 0.370663494839757 0.491566220400282 GO:0004857 enzyme inhibitor activity 2/58 416/18639 0.00480769230769231 1.5450099469496 0.372548945613158 0.491566220400282 GO:0008509 monoatomic anion transmembrane transporter activity 1/58 149/18639 0.00671140939597315 2.15679240916455 0.372637510160686 0.491566220400282 GO:0016887 ATP hydrolysis activity 2/58 417/18639 0.00479616306954436 1.54130488712478 0.373668583013441 0.491566220400282 GO:0019842 vitamin binding 1/58 150/18639 0.00666666666666667 2.14241379310345 0.374605440090955 0.491566220400282 GO:0000510 H3-H4 histone complex chaperone activity 1/58 151/18639 0.00662251655629139 2.12822562228819 0.376567303062166 0.491566220400282 GO:0140584 chromatin extrusion motor activity 1/58 151/18639 0.00662251655629139 2.12822562228819 0.376567303062166 0.491566220400282 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/58 151/18639 0.00662251655629139 2.12822562228819 0.376567303062166 0.491566220400282 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/58 151/18639 0.00662251655629139 2.12822562228819 0.376567303062166 0.491566220400282 GO:0015616 DNA translocase activity 1/58 152/18639 0.00657894736842105 2.11422413793103 0.378523117451088 0.491566220400282 GO:0140674 ATP-dependent histone chaperone activity 1/58 152/18639 0.00657894736842105 2.11422413793103 0.378523117451088 0.491566220400282 GO:0061775 cohesin loader activity 1/58 153/18639 0.0065359477124183 2.10040567951318 0.380472901579819 0.491872625015351 GO:0140658 ATP-dependent chromatin remodeler activity 1/58 158/18639 0.00632911392405063 2.03393714535137 0.390132005787028 0.502098141977027 GO:0003689 DNA clamp loader activity 1/58 160/18639 0.00625 2.00851293103448 0.393954070844149 0.502510303698981 GO:0015079 potassium ion transmembrane transporter activity 1/58 160/18639 0.00625 2.00851293103448 0.393954070844149 0.502510303698981 GO:0005178 integrin binding 1/58 161/18639 0.0062111801242236 1.996037695438 0.395856265978682 0.502702426264964 GO:0008083 growth factor activity 1/58 162/18639 0.00617283950617284 1.98371647509579 0.397752593317855 0.502885437366627 GO:0140713 histone chaperone activity 1/58 164/18639 0.00609756097560976 1.95952481076535 0.40152771569352 0.503381211921917 GO:0003779 actin binding 2/58 443/18639 0.00451467268623025 1.45084455514906 0.402496090340671 0.503381211921917 GO:0015103 inorganic anion transmembrane transporter activity 1/58 165/18639 0.00606060606060606 1.94764890282132 0.403406546139516 0.503381211921917 GO:0015399 primary active transmembrane transporter activity 1/58 166/18639 0.00602409638554217 1.93591607810553 0.405279579609469 0.503529174666309 GO:0046873 metal ion transmembrane transporter activity 2/58 450/18639 0.00444444444444444 1.42827586206897 0.41015697805852 0.507392468546531 GO:0004252 serine-type endopeptidase activity 1/58 176/18639 0.00568181818181818 1.82592084639498 0.423694920962125 0.521880476320711 GO:0043021 ribonucleoprotein complex binding 1/58 177/18639 0.00564971751412429 1.8156049094097 0.425505336094238 0.521880476320711 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/58 181/18639 0.00552486187845304 1.77548104400838 0.432691270754054 0.528435722154951 GO:1901981 phosphatidylinositol phosphate binding 1/58 185/18639 0.00540540540540541 1.73709226467847 0.439788852443674 0.534827968861587 GO:0140597 protein carrier chaperone 1/58 188/18639 0.00531914893617021 1.70937270726339 0.445054699717139 0.538650615396062 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/58 484/18639 0.00413223140495868 1.32794243374181 0.4466858761821 0.538650615396062 GO:0001216 DNA-binding transcription activator activity 2/58 491/18639 0.00407331975560081 1.30901046421799 0.45405671879027 0.544631385061532 GO:0008236 serine-type peptidase activity 1/58 194/18639 0.00515463917525773 1.65650551013153 0.455440879493964 0.544631385061532 GO:0005543 phospholipid binding 2/58 497/18639 0.00402414486921529 1.293207520988 0.460331597070178 0.548195719332535 GO:0017171 serine hydrolase activity 1/58 198/18639 0.00505050505050505 1.6230407523511 0.462258621032179 0.548215802629071 GO:0051015 actin filament binding 1/58 209/18639 0.00478468899521531 1.53761755485893 0.480577831265146 0.567192542427469 GO:0008094 ATP-dependent activity, acting on DNA 1/58 210/18639 0.00476190476190476 1.53029556650246 0.482212475095131 0.567192542427469 GO:0005539 glycosaminoglycan binding 1/58 242/18639 0.00413223140495868 1.32794243374181 0.531933557576399 0.576901212139878 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/58 243/18639 0.00411522633744856 1.32247765006386 0.533409225003728 0.576901212139878 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0004711 ribosomal protein S6 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0035175 histone H3S10 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0035979 histone H2AXS139 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0044022 histone H3S28 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0044023 histone H4S1 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0044024 histone H2AS1 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0044025 histone H2BS14 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0072354 histone H3T3 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0072371 histone H2AS121 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0140823 histone H2BS36 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0140855 histone H3S57 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0140995 histone H2A kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0140997 histone H4 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0140998 histone H2B kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:1990244 histone H2AT120 kinase activity 1/58 245/18639 0.00408163265306122 1.31168191414497 0.536346856712905 0.576901212139878 GO:0004677 DNA-dependent protein kinase activity 1/58 246/18639 0.0040650406504065 1.30634987384357 0.537808848792423 0.576901212139878 GO:0140857 histone H3T45 kinase activity 1/58 246/18639 0.0040650406504065 1.30634987384357 0.537808848792423 0.576901212139878 GO:0033218 amide binding 1/58 247/18639 0.00404858299595142 1.30106100795756 0.539266310151094 0.576901212139878 GO:0035402 histone H3T11 kinase activity 1/58 247/18639 0.00404858299595142 1.30106100795756 0.539266310151094 0.576901212139878 GO:0035403 histone H3T6 kinase activity 1/58 247/18639 0.00404858299595142 1.30106100795756 0.539266310151094 0.576901212139878 GO:0004679 AMP-activated protein kinase activity 1/58 248/18639 0.00403225806451613 1.2958147942158 0.540719254584067 0.576901212139878 GO:0019887 protein kinase regulator activity 1/58 255/18639 0.00392156862745098 1.26024340770791 0.550764541854542 0.584782984579394 GO:0003713 transcription coactivator activity 1/58 256/18639 0.00390625 1.25532058189655 0.552181842581937 0.584782984579394 GO:0008514 organic anion transmembrane transporter activity 1/58 269/18639 0.00371747211895911 1.19465453147032 0.570211675767355 0.601657172592761 GO:0005096 GTPase activator activity 1/58 271/18639 0.003690036900369 1.18583789286169 0.572921425007397 0.602302010905213 GO:0016791 phosphatase activity 1/58 273/18639 0.00366300366300366 1.17715043577113 0.575614382430677 0.602924553859869 GO:0008017 microtubule binding 1/58 276/18639 0.0036231884057971 1.16435532233883 0.579622557394873 0.604915178081195 GO:0035091 phosphatidylinositol binding 1/58 284/18639 0.00352112676056338 1.1315565808645 0.590130032830681 0.613649708052193 GO:0003924 GTPase activity 1/58 331/18639 0.00302114803625378 0.970882383581623 0.646846637579942 0.670198501752503 GO:0106310 protein serine kinase activity 1/58 361/18639 0.00277008310249307 0.890199637023593 0.67893758572053 0.700498086793996 GO:0042578 phosphoric ester hydrolase activity 1/58 363/18639 0.00275482093663912 0.885294955827871 0.680972007719599 0.700498086793996 GO:0046982 protein heterodimerization activity 1/58 369/18639 0.002710027100271 0.870899915895711 0.686999561578525 0.704174550617988 GO:0015631 tubulin binding 1/58 385/18639 0.0025974025974026 0.834706672637707 0.702531238814504 0.717531905835454 GO:0004175 endopeptidase activity 1/58 405/18639 0.00246913580246914 0.793486590038314 0.720884094953694 0.733665727842944 GO:0004674 protein serine/threonine kinase activity 1/58 433/18639 0.0023094688221709 0.742175678904197 0.744721636794348 0.755247737667767 GO:0022804 active transmembrane transporter activity 1/58 457/18639 0.00218818380743982 0.703199275635705 0.763552612628575 0.771618309240849 GO:0030695 GTPase regulator activity 1/58 489/18639 0.00204498977505112 0.657182145123757 0.786551373603145 0.789986032962004 GO:0060589 nucleoside-triphosphatase regulator activity 1/58 490/18639 0.00204081632653061 0.655840957072484 0.787233468387224 0.789986032962004 GO:0003712 transcription coregulator activity 1/58 495/18639 0.00202020202020202 0.649216300940439 0.79061194070676 0.79061194070676