ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 185/3674 495/18639 0.373737373737374 1.89605087345969 1.82340169668184e-20 2.44700507694704e-17 GO:0140297 DNA-binding transcription factor binding 171/3674 488/18639 0.350409836065574 1.77770520806375 7.15120613698055e-16 4.79845931791395e-13 GO:0003713 transcription coactivator activity 100/3674 256/18639 0.390625 1.98172546951551 5.12024063089382e-13 2.10478244092346e-10 GO:0019787 ubiquitin-like protein transferase activity 160/3674 479/18639 0.334029227557411 1.69460282320158 6.27356912346785e-13 2.10478244092346e-10 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 125/3674 349/18639 0.358166189111748 1.81705487176208 1.03669331370169e-12 2.78248485397532e-10 GO:0004842 ubiquitin-protein transferase activity 151/3674 449/18639 0.33630289532294 1.7061376336212 1.55340258038735e-12 3.47444377146637e-10 GO:0016755 aminoacyltransferase activity 161/3674 496/18639 0.324596774193548 1.64674993853934 7.24702078104354e-12 1.38935741259435e-09 GO:0030695 GTPase regulator activity 159/3674 489/18639 0.325153374233129 1.64957369143475 8.42581626807374e-12 1.41343067896937e-09 GO:0060589 nucleoside-triphosphatase regulator activity 159/3674 490/18639 0.324489795918367 1.64620721451346 1.00873521967682e-11 1.50413629422921e-09 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 150/3674 484/18639 0.309917355371901 1.57227805845859 1.52233624890723e-09 2.04297524603351e-07 GO:0001216 DNA-binding transcription activator activity 151/3674 491/18639 0.307535641547862 1.56019510691633 2.4214695729642e-09 2.86733290158023e-07 GO:0061659 ubiquitin-like protein ligase activity 121/3674 372/18639 0.325268817204301 1.65015935870195 2.56393404016116e-09 2.86733290158023e-07 GO:0042393 histone binding 87/3674 247/18639 0.352226720647773 1.78692265818014 7.10025059823944e-09 7.32964330987486e-07 GO:0001221 transcription coregulator binding 49/3674 115/18639 0.426086956521739 2.16163167735675 1.62394739917499e-08 1.55666957835203e-06 GO:0061630 ubiquitin protein ligase activity 113/3674 353/18639 0.320113314447592 1.62400437343186 2.29712167770961e-08 2.05515819432419e-06 GO:0016922 nuclear receptor binding 55/3674 137/18639 0.401459854014599 2.0366930372831 2.77010391384765e-08 2.32342465773972e-06 GO:0003714 transcription corepressor activity 73/3674 204/18639 0.357843137254902 1.8154159595248 5.38271246046791e-08 4.24917654232231e-06 GO:0004674 protein serine/threonine kinase activity 131/3674 433/18639 0.302540415704388 1.53485324123954 7.95295127588314e-08 5.92936700679732e-06 GO:0005096 GTPase activator activity 90/3674 271/18639 0.33210332103321 1.68483228109363 9.45141823848356e-08 6.67568593476049e-06 GO:0106310 protein serine kinase activity 112/3674 361/18639 0.310249307479224 1.57396212359969 1.66898120443309e-07 1.1198863881746e-05 GO:0046966 nuclear thyroid hormone receptor binding 18/3674 28/18639 0.642857142857143 3.26135391554553 3.29140103295392e-07 2.10336199344008e-05 GO:0031267 small GTPase binding 91/3674 283/18639 0.321554770318021 1.63131719214959 4.15448326708591e-07 2.53423479292241e-05 GO:0005085 guanyl-nucleotide exchange factor activity 77/3674 230/18639 0.334782608695652 1.69842488935173 5.42605548841666e-07 3.16598541976311e-05 GO:0023026 MHC class II protein complex binding 17/3674 27/18639 0.62962962962963 3.19424786790056 1.08535063617147e-06 6.06891897392549e-05 GO:0001217 DNA-binding transcription repressor activity 88/3674 278/18639 0.316546762589928 1.60591048119588 1.34468429584474e-06 7.21826530009455e-05 GO:0001223 transcription coactivator binding 23/3674 44/18639 0.522727272727273 2.65190899193349 1.4718158559882e-06 7.59683414898527e-05 GO:0051020 GTPase binding 97/3674 315/18639 0.307936507936508 1.5622287891749 1.58157352616305e-06 7.861006193003e-05 GO:0140030 modification-dependent protein binding 60/3674 173/18639 0.346820809248555 1.75949729547736 2.5962625890695e-06 0.000124435156947546 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 84/3674 268/18639 0.313432835820896 1.59011285434558 3.58189140343341e-06 0.000165755112531298 GO:0019902 phosphatase binding 64/3674 190/18639 0.336842105263158 1.70887316276538 3.76898339856768e-06 0.000168599190695928 GO:0032182 ubiquitin-like protein binding 45/3674 120/18639 0.375 1.90245645073489 4.43425370652135e-06 0.00019196027335973 GO:0010485 histone H4 acetyltransferase activity 19/3674 35/18639 0.542857142857143 2.75403219534956 5.81717827701349e-06 0.000243957913992253 GO:0043130 ubiquitin binding 39/3674 100/18639 0.39 1.97855470876429 6.36185601046819e-06 0.000256484592368037 GO:0140034 methylation-dependent protein binding 32/3674 76/18639 0.421052631578947 2.13609145345672 6.49811932974162e-06 0.000256484592368037 GO:0023023 MHC protein complex binding 19/3674 37/18639 0.513513513513513 2.60516559019553 1.68376431982434e-05 0.000645603347772646 GO:0035064 methylated histone binding 30/3674 74/18639 0.405405405405405 2.05670967647016 3.02344500905784e-05 0.0011270731117099 GO:0019207 kinase regulator activity 85/3674 287/18639 0.29616724738676 1.50252077409957 3.41858653018737e-05 0.00123993057392201 GO:0140693 molecular condensate scaffold activity 22/3674 48/18639 0.458333333333333 2.3252245508982 3.6962213055105e-05 0.00130534973473555 GO:0043995 histone H4K5 acetyltransferase activity 16/3674 30/18639 0.533333333333333 2.70571584104518 4.27717375063606e-05 0.00139421430728647 GO:0043996 histone H4K8 acetyltransferase activity 16/3674 30/18639 0.533333333333333 2.70571584104518 4.27717375063606e-05 0.00139421430728647 GO:0043997 histone H4K12 acetyltransferase activity 16/3674 30/18639 0.533333333333333 2.70571584104518 4.27717375063606e-05 0.00139421430728647 GO:0044389 ubiquitin-like protein ligase binding 93/3674 322/18639 0.288819875776398 1.46524596205669 4.36341288420504e-05 0.00139421430728647 GO:0004679 AMP-activated protein kinase activity 75/3674 248/18639 0.30241935483871 1.5342390731733 4.51633288303829e-05 0.00140951598349706 GO:0042277 peptide binding 75/3674 249/18639 0.301204819277108 1.52807747046979 5.23319582516891e-05 0.00159612472667652 GO:0140857 histone H3T45 kinase activity 74/3674 246/18639 0.300813008130081 1.52608972741878 6.1286260336023e-05 0.00181431573476251 GO:0140767 enzyme-substrate adaptor activity 47/3674 139/18639 0.338129496402878 1.71540437764106 6.21896600589237e-05 0.00181431573476251 GO:0048156 tau protein binding 20/3674 43/18639 0.465116279069767 2.35963590788824 6.39644412521239e-05 0.00182638893958192 GO:0036408 histone H3K14 acetyltransferase activity 15/3674 28/18639 0.535714285714286 2.71779492962128 6.94720289963801e-05 0.0019214359165983 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 73/3674 243/18639 0.300411522633745 1.52405290429243 7.17645999923531e-05 0.0019214359165983 GO:0004676 3-phosphoinositide-dependent protein kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0004711 ribosomal protein S6 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0035175 histone H3S10 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0035979 histone H2AXS139 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0044022 histone H3S28 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0044023 histone H4S1 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0044024 histone H2AS1 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0044025 histone H2BS14 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0072354 histone H3T3 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0072371 histone H2AS121 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0072518 Rho-dependent protein serine/threonine kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0140823 histone H2BS36 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0140855 histone H3S57 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0140995 histone H2A kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0140997 histone H4 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0140998 histone H2B kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:1990244 histone H2AT120 kinase activity 73/3674 245/18639 0.297959183673469 1.51161165609412 9.56668889855287e-05 0.0019214359165983 GO:0016407 acetyltransferase activity 35/3674 96/18639 0.364583333333333 1.84961043821448 9.59286187869492e-05 0.0019214359165983 GO:0042578 phosphoric ester hydrolase activity 101/3674 363/18639 0.278236914600551 1.41155630137171 0.000104868337448527 0.00206960748317535 GO:0004677 DNA-dependent protein kinase activity 73/3674 246/18639 0.296747967479675 1.50546689326447 0.000110174321883875 0.00214281072417624 GO:1990841 promoter-specific chromatin binding 27/3674 68/18639 0.397058823529412 2.0143656537193 0.000113326480317134 0.00217263052265134 GO:0010484 histone H3 acetyltransferase activity 15/3674 29/18639 0.517241379310345 2.62407786308261 0.000117736191617643 0.00222537984719544 GO:0019887 protein kinase regulator activity 75/3674 255/18639 0.294117647058824 1.49212270645874 0.000122305871690293 0.00227964555289407 GO:0035402 histone H3T11 kinase activity 73/3674 247/18639 0.295546558704453 1.49937188559943 0.0001266692625092 0.00229716419307224 GO:0035403 histone H3T6 kinase activity 73/3674 247/18639 0.295546558704453 1.49937188559943 0.0001266692625092 0.00229716419307224 GO:0031490 chromatin DNA binding 43/3674 128/18639 0.3359375 1.70428390378334 0.000147604821824947 0.00264114227852106 GO:0004402 histone acetyltransferase activity 19/3674 42/18639 0.452380952380952 2.29502682945797 0.000153955008161873 0.00271852132833202 GO:0141003 histone H2AX kinase activity 98/3674 354/18639 0.27683615819209 1.40444995986455 0.000161087112027006 0.0027701634335452 GO:0019903 protein phosphatase binding 47/3674 144/18639 0.326388888888889 1.65584172563963 0.000163072214046252 0.0027701634335452 GO:0019955 cytokine binding 47/3674 144/18639 0.326388888888889 1.65584172563963 0.000163072214046252 0.0027701634335452 GO:0000149 SNARE binding 37/3674 106/18639 0.349056603773585 1.77083996672179 0.000173944583906403 0.00291792039502991 GO:0043998 histone H2A acetyltransferase activity 13/3674 24/18639 0.541666666666667 2.74799265106151 0.000183989599213452 0.00301114685542016 GO:0140033 acetylation-dependent protein binding 13/3674 24/18639 0.541666666666667 2.74799265106151 0.000183989599213452 0.00301114685542016 GO:0035173 histone kinase activity 99/3674 360/18639 0.275 1.39513473053892 0.00019490004643594 0.00315127544960279 GO:0034450 ubiquitin-ubiquitin ligase activity 10/3674 16/18639 0.625 3.17076075122482 0.00021662481630888 0.00346083932722043 GO:0140996 histone H3 kinase activity 98/3674 357/18639 0.274509803921569 1.39264785936149 0.000224385852658556 0.0035045958481074 GO:0034212 protein N-acetyltransferase activity 22/3674 53/18639 0.415094339622642 2.10586374420969 0.000224586619178269 0.0035045958481074 GO:0031625 ubiquitin protein ligase binding 85/3674 302/18639 0.281456953642384 1.42789225882972 0.000235597211630395 0.00363415468974701 GO:0061733 protein-lysine-acetyltransferase activity 20/3674 47/18639 0.425531914893617 2.15881583062116 0.000288100251903734 0.00439352884153194 GO:0002039 p53 binding 26/3674 69/18639 0.376811594202899 1.91164706160801 0.000402309232280244 0.00606628078337178 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 40/3674 122/18639 0.327868852459016 1.66334990228187 0.000434773164247487 0.00648295096022364 GO:0042605 peptide antigen binding 19/3674 45/18639 0.422222222222222 2.14202504082744 0.000457513648976501 0.00674706941677433 GO:0045296 cadherin binding 91/3674 334/18639 0.272455089820359 1.38222384843813 0.000482016785382096 0.00703115789111709 GO:0044013 histone H2B acetyltransferase activity 12/3674 23/18639 0.521739130434783 2.64689593145724 0.000515240835890582 0.00735588512516129 GO:0070577 lysine-acetylated histone binding 12/3674 23/18639 0.521739130434783 2.64689593145724 0.000515240835890582 0.00735588512516129 GO:0035497 cAMP response element binding 8/3674 12/18639 0.666666666666667 3.38214480130648 0.000521388649065861 0.00736530070575143 GO:0004721 phosphoprotein phosphatase activity 53/3674 175/18639 0.302857142857143 1.53646006687923 0.000529456219535484 0.00740135673558979 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 66/3674 229/18639 0.2882096069869 1.46214993593599 0.000556251125147439 0.00769576298915323 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 41/3674 128/18639 0.3203125 1.62501488500272 0.000634810060386332 0.00869301123508629 GO:0002020 protease binding 43/3674 136/18639 0.316176470588235 1.60403190944315 0.00064395126258671 0.00872911711506429 GO:1990782 protein tyrosine kinase binding 38/3674 117/18639 0.324786324786325 1.64771156986726 0.000731598853896571 0.00981805661929198 GO:0030228 lipoprotein particle receptor activity 10/3674 18/18639 0.555555555555556 2.81845400108873 0.000802597763774864 0.0106642197919393 GO:0001540 amyloid-beta binding 29/3674 83/18639 0.349397590361446 1.77256986574496 0.000821091886962602 0.01072794561986 GO:0030331 nuclear estrogen receptor binding 17/3674 40/18639 0.425 2.15611731083288 0.000823381817321591 0.01072794561986 GO:0035035 histone acetyltransferase binding 12/3674 24/18639 0.5 2.53660860097986 0.000846492072567712 0.0109230034748641 GO:0008081 phosphoric diester hydrolase activity 30/3674 87/18639 0.344827586206897 1.74938524205507 0.000862698249382162 0.0110261052444844 GO:0043394 proteoglycan binding 16/3674 37/18639 0.432432432432432 2.1938236549015 0.000927822623815292 0.0117465845392464 GO:0008080 N-acetyltransferase activity 25/3674 69/18639 0.36231884057971 1.83812217462309 0.00100829801665797 0.0126461302649999 GO:0140789 histone phosphatase activity 42/3674 136/18639 0.308823529411765 1.56672884178168 0.00124656009862622 0.0152047094565406 GO:0070063 RNA polymerase binding 22/3674 59/18639 0.372881355932203 1.89170810920532 0.00128349955868824 0.0152047094565406 GO:0042974 nuclear retinoic acid receptor binding 12/3674 25/18639 0.48 2.43514425694066 0.00133772864278113 0.0152047094565406 GO:0032931 histone H3K56 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0043992 histone H3K9 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0043993 histone H3K18 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0043994 histone H3K23 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0043999 histone H2AK5 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0044012 histone H2AK9 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0044014 histone H2BK5 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0044015 histone H2BK12 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0044016 histone H3K4 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0044017 histone H3K27 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0044018 histone H3K36 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0046972 histone H4K16 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0140908 histone H3K122 acetyltransferase activity 11/3674 22/18639 0.5 2.53660860097986 0.00139357620205252 0.0152047094565406 GO:0035591 signaling adaptor activity 40/3674 129/18639 0.310077519379845 1.57309060525883 0.00147491829800623 0.0159624222251964 GO:0061631 ubiquitin conjugating enzyme activity 15/3674 35/18639 0.428571428571429 2.17423594369702 0.00148713106605118 0.0159658391251255 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 22/3674 60/18639 0.366666666666667 1.86017964071856 0.00165442532909682 0.0176209427908566 GO:0140296 general transcription initiation factor binding 20/3674 53/18639 0.377358490566038 1.91442158564518 0.00177209755748333 0.0187256293082097 GO:0008432 JUN kinase binding 7/3674 11/18639 0.636363636363636 3.22841094670164 0.0017906889618337 0.0187742545842252 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 28/3674 83/18639 0.337349397590361 1.71144676692617 0.0018391869004472 0.0191332466697685 GO:0050681 nuclear androgen receptor binding 12/3674 26/18639 0.461538461538462 2.34148486244295 0.00204236044812646 0.0210834440106593 GO:0015026 coreceptor activity 22/3674 61/18639 0.360655737704918 1.82968489251006 0.00211290897480838 0.0216452201846782 GO:0140375 immune receptor activity 46/3674 156/18639 0.294871794871795 1.49594866211633 0.00216389918437916 0.0219996417078548 GO:0019209 kinase activator activity 44/3674 148/18639 0.297297297297297 1.50825376274478 0.00223954131702776 0.0225974770485056 GO:0071889 14-3-3 protein binding 14/3674 33/18639 0.424242424242424 2.15227396446776 0.00238308500124001 0.0236896301604748 GO:0140311 protein sequestering activity 14/3674 33/18639 0.424242424242424 2.15227396446776 0.00238308500124001 0.0236896301604748 GO:0140938 histone H3 methyltransferase activity 18/3674 47/18639 0.382978723404255 1.94293424755904 0.00243995964164138 0.0240766605814907 GO:0032452 histone demethylase activity 13/3674 30/18639 0.433333333333333 2.19839412084921 0.00269751033927331 0.0264237874109838 GO:0051219 phosphoprotein binding 30/3674 93/18639 0.32258064516129 1.63652167805152 0.00282318761791042 0.0274544766901144 GO:0140313 molecular sequestering activity 20/3674 55/18639 0.363636363636364 1.84480625525808 0.00295506425918987 0.0285301887469986 GO:0004725 protein tyrosine phosphatase activity 31/3674 98/18639 0.316326530612245 1.60479319653828 0.00339717225091772 0.0325643225766542 GO:0035091 phosphatidylinositol binding 75/3674 284/18639 0.264084507042254 1.33975806389781 0.00348234964866139 0.03314406545038 GO:0070008 serine-type exopeptidase activity 7/3674 12/18639 0.583333333333333 2.95937670114317 0.00356770939970868 0.0337173662986553 GO:0140457 protein demethylase activity 13/3674 31/18639 0.419354838709677 2.12747818146698 0.00381756492882165 0.035550590361251 GO:0005041 low-density lipoprotein particle receptor activity 8/3674 15/18639 0.533333333333333 2.70571584104518 0.00384115916719925 0.035550590361251 GO:0042809 nuclear vitamin D receptor binding 8/3674 15/18639 0.533333333333333 2.70571584104518 0.00384115916719925 0.035550590361251 GO:0030165 PDZ domain binding 27/3674 83/18639 0.325301204819277 1.65032366810738 0.00392032162090996 0.0360347370908299 GO:0004722 protein serine/threonine phosphatase activity 32/3674 103/18639 0.310679611650485 1.57614515012341 0.00402306755033002 0.036727596275802 GO:0001222 transcription corepressor binding 18/3674 49/18639 0.36734693877551 1.86363080888316 0.00413437542214565 0.0374887284899964 GO:0097718 disordered domain specific binding 12/3674 28/18639 0.428571428571429 2.17423594369702 0.00435323800755464 0.0389469693742555 GO:0141052 histone H3 demethylase activity 12/3674 28/18639 0.428571428571429 2.17423594369702 0.00435323800755464 0.0389469693742555 GO:0003779 actin binding 110/3674 443/18639 0.248306997742664 1.25971533231505 0.00443395577904201 0.0392265902614432 GO:0061775 cohesin loader activity 44/3674 153/18639 0.287581699346405 1.45896442409299 0.00444634215180513 0.0392265902614432 GO:0005518 collagen binding 24/3674 72/18639 0.333333333333333 1.69107240065324 0.00447218204918093 0.0392265902614432 GO:0004860 protein kinase inhibitor activity 27/3674 84/18639 0.321428571428571 1.63067695777277 0.00471237281707977 0.0410649631202666 GO:0019905 syntaxin binding 21/3674 61/18639 0.344262295081967 1.74651739739597 0.00496975910243867 0.0430284949385335 GO:0038024 cargo receptor activity 22/3674 65/18639 0.338461538461538 1.71708889912483 0.00516301372167566 0.0444151565031329 GO:0019208 phosphatase regulator activity 35/3674 117/18639 0.299145299145299 1.51762907750932 0.00534362133673356 0.0446093099651196 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 10/3674 22/18639 0.454545454545455 2.3060078190726 0.0054845438291951 0.0446093099651196 GO:0050321 tau-protein kinase activity 10/3674 22/18639 0.454545454545455 2.3060078190726 0.0054845438291951 0.0446093099651196 GO:0140517 protein-RNA adaptor activity 10/3674 22/18639 0.454545454545455 2.3060078190726 0.0054845438291951 0.0446093099651196 GO:0033192 calmodulin-dependent protein phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0140791 histone H2AXS140 phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:1990439 MAP kinase serine/threonine phosphatase activity 26/3674 81/18639 0.320987654320988 1.62844008951793 0.00559519418524235 0.0446093099651196 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 28/3674 89/18639 0.314606741573034 1.59606833320081 0.00565095580780203 0.0446093099651196 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 28/3674 89/18639 0.314606741573034 1.59606833320081 0.00565095580780203 0.0446093099651196 GO:0016298 lipase activity 38/3674 130/18639 0.292307692307692 1.48294041288053 0.00583627870708758 0.0451893021054999 GO:0008140 cAMP response element binding protein binding 6/3674 10/18639 0.6 3.04393032117583 0.00589279274848173 0.0451893021054999 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 6/3674 10/18639 0.6 3.04393032117583 0.00589279274848173 0.0451893021054999 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 6/3674 10/18639 0.6 3.04393032117583 0.00589279274848173 0.0451893021054999 GO:0032395 MHC class II receptor activity 6/3674 10/18639 0.6 3.04393032117583 0.00589279274848173 0.0451893021054999 GO:0043395 heparan sulfate proteoglycan binding 9/3674 19/18639 0.473684210526316 2.40310288513881 0.00599853072946007 0.0454803855307085 GO:0046527 glucosyltransferase activity 9/3674 19/18639 0.473684210526316 2.40310288513881 0.00599853072946007 0.0454803855307085 GO:0005484 SNAP receptor activity 14/3674 36/18639 0.388888888888889 1.97291780076211 0.00611698084182064 0.0461179117400186 GO:0001784 phosphotyrosine residue binding 17/3674 47/18639 0.361702127659574 1.83499345602798 0.00627897235888991 0.0470747536627389 GO:0005521 lamin binding 8/3674 16/18639 0.5 2.53660860097986 0.00636571997280343 0.0474599789083456 GO:0016791 phosphatase activity 71/3674 273/18639 0.26007326007326 1.31940813677341 0.00646414565912696 0.0479275330085546 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 26/3674 82/18639 0.317073170731707 1.60858106403601 0.00668713299066276 0.0488024137001378 GO:0033549 MAP kinase phosphatase activity 26/3674 82/18639 0.317073170731707 1.60858106403601 0.00668713299066276 0.0488024137001378 GO:0140793 histone H2AXY142 phosphatase activity 28/3674 90/18639 0.311111111111111 1.57833424060969 0.00669124003042128 0.0488024137001378 GO:0032451 demethylase activity 15/3674 40/18639 0.375 1.90245645073489 0.00684012238852566 0.0496186175427104 GO:0052742 phosphatidylinositol kinase activity 11/3674 26/18639 0.423076923076923 2.14636112390603 0.00702750383086687 0.0507038179624911 GO:0140416 transcription regulator inhibitor activity 13/3674 33/18639 0.393939393939394 1.99854010986292 0.00717204060035809 0.0514699384260993 GO:0045309 protein phosphorylated amino acid binding 20/3674 59/18639 0.338983050847458 1.71973464473211 0.00732005261237535 0.0522527159883389 GO:0003725 double-stranded RNA binding 24/3674 75/18639 0.32 1.62342950462711 0.00790095698677034 0.0560012613398727 GO:0046332 SMAD binding 25/3674 79/18639 0.316455696202532 1.60544848163282 0.0079411198485749 0.0560012613398727 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 10/3674 23/18639 0.434782608695652 2.2057466095477 0.00801210296367777 0.0560012613398727 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 10/3674 23/18639 0.434782608695652 2.2057466095477 0.00801210296367777 0.0560012613398727 GO:0140658 ATP-dependent chromatin remodeler activity 44/3674 158/18639 0.278481012658228 1.41279466383688 0.00828774883899466 0.0576277665385017 GO:0001968 fibronectin binding 12/3674 30/18639 0.4 2.02928688078389 0.00838923504077664 0.0577351457678064 GO:0031624 ubiquitin conjugating enzyme binding 12/3674 30/18639 0.4 2.02928688078389 0.00838923504077664 0.0577351457678064 GO:0042169 SH2 domain binding 15/3674 41/18639 0.365853658536585 1.8560550738877 0.00885675901687272 0.0603338609169705 GO:0061650 ubiquitin-like protein conjugating enzyme activity 15/3674 41/18639 0.365853658536585 1.8560550738877 0.00885675901687272 0.0603338609169705 GO:0015095 magnesium ion transmembrane transporter activity 9/3674 20/18639 0.45 2.28294774088187 0.00902290719366808 0.0611552598681948 GO:0004896 cytokine receptor activity 29/3674 96/18639 0.302083333333333 1.532534363092 0.00914059383744844 0.0616415926123408 GO:0004197 cysteine-type endopeptidase activity 27/3674 88/18639 0.306818181818182 1.556555277874 0.0093370110985424 0.0626513444712195 GO:0017018 myosin phosphatase activity 26/3674 84/18639 0.30952380952381 1.57028151489229 0.00940017310221455 0.0627613547421489 GO:0005044 scavenger receptor activity 11/3674 27/18639 0.407407407407407 2.06686626746507 0.00978030707756159 0.063413182181275 GO:0000510 H3-H4 histone complex chaperone activity 42/3674 151/18639 0.278145695364238 1.4110935263729 0.00993294566185745 0.063413182181275 GO:0140584 chromatin extrusion motor activity 42/3674 151/18639 0.278145695364238 1.4110935263729 0.00993294566185745 0.063413182181275 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 42/3674 151/18639 0.278145695364238 1.4110935263729 0.00993294566185745 0.063413182181275 GO:0140849 ATP-dependent H2AZ histone chaperone activity 42/3674 151/18639 0.278145695364238 1.4110935263729 0.00993294566185745 0.063413182181275 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 8/3674 17/18639 0.470588235294118 2.38739633033398 0.00997032894206336 0.063413182181275 GO:0008429 phosphatidylethanolamine binding 8/3674 17/18639 0.470588235294118 2.38739633033398 0.00997032894206336 0.063413182181275 GO:0019198 transmembrane receptor protein phosphatase activity 8/3674 17/18639 0.470588235294118 2.38739633033398 0.00997032894206336 0.063413182181275 GO:0036041 long-chain fatty acid binding 8/3674 17/18639 0.470588235294118 2.38739633033398 0.00997032894206336 0.063413182181275 GO:0046965 nuclear retinoid X receptor binding 8/3674 17/18639 0.470588235294118 2.38739633033398 0.00997032894206336 0.063413182181275 GO:0051018 protein kinase A binding 18/3674 53/18639 0.339622641509434 1.72297942708066 0.0104132125823138 0.0658882477826578 GO:0003689 DNA clamp loader activity 44/3674 160/18639 0.275 1.39513473053892 0.0104576727106603 0.0658882477826578 GO:0008474 palmitoyl-(protein) hydrolase activity 7/3674 14/18639 0.5 2.53660860097986 0.0106794350248227 0.0659734354840021 GO:0061665 SUMO ligase activity 7/3674 14/18639 0.5 2.53660860097986 0.0106794350248227 0.0659734354840021 GO:0098599 palmitoyl hydrolase activity 7/3674 14/18639 0.5 2.53660860097986 0.0106794350248227 0.0659734354840021 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 6/3674 11/18639 0.545454545454545 2.76720938288712 0.0108153172924594 0.0659734354840021 GO:0005114 type II transforming growth factor beta receptor binding 6/3674 11/18639 0.545454545454545 2.76720938288712 0.0108153172924594 0.0659734354840021 GO:0048185 activin binding 6/3674 11/18639 0.545454545454545 2.76720938288712 0.0108153172924594 0.0659734354840021 GO:0180030 inositol phosphate kinase activity 6/3674 11/18639 0.545454545454545 2.76720938288712 0.0108153172924594 0.0659734354840021 GO:0030295 protein kinase activator activity 39/3674 139/18639 0.280575539568345 1.42342065378726 0.0108961768610503 0.0661659246494549 GO:0015616 DNA translocase activity 42/3674 152/18639 0.276315789473684 1.40181001633097 0.0111692513609127 0.0672158534813668 GO:0140674 ATP-dependent histone chaperone activity 42/3674 152/18639 0.276315789473684 1.40181001633097 0.0111692513609127 0.0672158534813668 GO:0004622 lysophospholipase activity 10/3674 24/18639 0.416666666666667 2.11384050081655 0.0113472427670422 0.0679821419346903 GO:0042826 histone deacetylase binding 36/3674 127/18639 0.283464566929134 1.43807731709094 0.0118998102262754 0.0709757569940513 GO:0016410 N-acyltransferase activity 28/3674 94/18639 0.297872340425532 1.51117108143481 0.0125562567172848 0.0745597190911334 GO:0019838 growth factor binding 38/3674 136/18639 0.279411764705882 1.4175165711358 0.0126888460955916 0.0750151165651273 GO:0019210 kinase inhibitor activity 27/3674 90/18639 0.3 1.52196516058791 0.0127640810228982 0.075128933038287 GO:0019789 SUMO transferase activity 11/3674 28/18639 0.392857142857143 1.9930496150556 0.0132919400052131 0.0778942510349171 GO:0019888 protein phosphatase regulator activity 31/3674 107/18639 0.289719626168224 1.46981059122197 0.0135897025320558 0.0792929599913867 GO:0051059 NF-kappaB binding 12/3674 32/18639 0.375 1.90245645073489 0.014871279620058 0.0850417661794795 GO:0043495 protein-membrane adaptor activity 16/3674 47/18639 0.340425531914894 1.72705266449692 0.0148744161396074 0.0850417661794795 GO:0000900 mRNA regulatory element binding translation repressor activity 8/3674 18/18639 0.444444444444444 2.25476320087099 0.0148918144949163 0.0850417661794795 GO:0004706 JUN kinase kinase kinase activity 8/3674 18/18639 0.444444444444444 2.25476320087099 0.0148918144949163 0.0850417661794795 GO:0034185 apolipoprotein binding 8/3674 18/18639 0.444444444444444 2.25476320087099 0.0148918144949163 0.0850417661794795 GO:0004709 MAP kinase kinase kinase activity 10/3674 25/18639 0.4 2.02928688078389 0.0156331348068039 0.0881739589132937 GO:0017025 TBP-class protein binding 10/3674 25/18639 0.4 2.02928688078389 0.0156331348068039 0.0881739589132937 GO:0004386 helicase activity 42/3674 155/18639 0.270967741935484 1.37467820956328 0.0156580097904341 0.0881739589132937 GO:0019003 GDP binding 23/3674 75/18639 0.306666666666667 1.55578660860098 0.0157031119078072 0.0881739589132937 GO:0016409 palmitoyltransferase activity 13/3674 36/18639 0.361111111111111 1.83199510070768 0.0161223245882767 0.0897765958401134 GO:0044390 ubiquitin-like protein conjugating enzyme binding 13/3674 36/18639 0.361111111111111 1.83199510070768 0.0161223245882767 0.0897765958401134 GO:0047372 monoacylglycerol lipase activity 7/3674 15/18639 0.466666666666667 2.36750136091453 0.0166629264002432 0.0920232396260345 GO:0120283 protein serine/threonine kinase binding 7/3674 15/18639 0.466666666666667 2.36750136091453 0.0166629264002432 0.0920232396260345 GO:0043236 laminin binding 11/3674 29/18639 0.379310344827586 1.92432376626058 0.0176793479660697 0.0961922444386981 GO:0016790 thiolester hydrolase activity 15/3674 44/18639 0.340909090909091 1.72950586430445 0.0178102083497568 0.0961922444386981 GO:0005078 MAP-kinase scaffold activity 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:0035259 nuclear glucocorticoid receptor binding 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:1990247 N6-methyladenosine-containing RNA reader activity 6/3674 12/18639 0.5 2.53660860097986 0.0180629251852101 0.0961922444386981 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 16/3674 48/18639 0.333333333333333 1.69107240065324 0.0183265557002044 0.0968277076758833 GO:0032266 phosphatidylinositol-3-phosphate binding 16/3674 48/18639 0.333333333333333 1.69107240065324 0.0183265557002044 0.0968277076758833 GO:0140097 catalytic activity, acting on DNA 82/3674 336/18639 0.244047619047619 1.23810657904969 0.0191529891260338 0.100797299635833 GO:0051213 dioxygenase activity 27/3674 93/18639 0.290322580645161 1.47286951024637 0.0197297163462217 0.103426872408709 GO:0140597 protein carrier chaperone 49/3674 188/18639 0.26063829787234 1.32227469625546 0.0199638206332591 0.104246876614139 GO:0005160 transforming growth factor beta receptor binding 10/3674 26/18639 0.384615384615385 1.95123738536912 0.0210116541667644 0.108452461122299 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 10/3674 26/18639 0.384615384615385 1.95123738536912 0.0210116541667644 0.108452461122299 GO:0043548 phosphatidylinositol 3-kinase binding 10/3674 26/18639 0.384615384615385 1.95123738536912 0.0210116541667644 0.108452461122299 GO:0016763 pentosyltransferase activity 16/3674 49/18639 0.326530612244898 1.65656071900725 0.0223598504074885 0.11496903925996 GO:1901505 carbohydrate derivative transmembrane transporter activity 17/3674 53/18639 0.320754716981132 1.6272583477984 0.0225691951782899 0.115602518813989 GO:1901981 phosphatidylinositol phosphate binding 48/3674 185/18639 0.259459459459459 1.3162941929409 0.0228151683363306 0.11641808329793 GO:0035925 mRNA 3'-UTR AU-rich region binding 11/3674 30/18639 0.366666666666667 1.86017964071856 0.0230578343965024 0.11721065818222 GO:0004707 MAP kinase activity 7/3674 16/18639 0.4375 2.21953252585738 0.0246718647326964 0.124942047061428 GO:0005158 insulin receptor binding 9/3674 23/18639 0.391304347826087 1.98517194859293 0.0249526111708899 0.125888737561407 GO:0140713 histone chaperone activity 43/3674 164/18639 0.26219512195122 1.33017280295285 0.0252781988498228 0.127053718563529 GO:0097110 scaffold protein binding 21/3674 70/18639 0.3 1.52196516058791 0.0259444979439193 0.129916105375894 GO:0043175 RNA polymerase core enzyme binding 14/3674 42/18639 0.333333333333333 1.69107240065324 0.0263759075224136 0.131585382509587 GO:0003925 G protein activity 17/3674 54/18639 0.314814814814815 1.59712393395028 0.0270554305181427 0.134475510204991 GO:0031406 carboxylic acid binding 48/3674 187/18639 0.25668449197861 1.30221618018217 0.0274005110935514 0.135688139806443 GO:0004535 poly(A)-specific ribonuclease activity 6/3674 13/18639 0.461538461538462 2.34148486244295 0.0280407883301984 0.136343253402632 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 6/3674 13/18639 0.461538461538462 2.34148486244295 0.0280407883301984 0.136343253402632 GO:0031994 insulin-like growth factor I binding 6/3674 13/18639 0.461538461538462 2.34148486244295 0.0280407883301984 0.136343253402632 GO:0046974 histone H3K9 methyltransferase activity 6/3674 13/18639 0.461538461538462 2.34148486244295 0.0280407883301984 0.136343253402632 GO:0046975 histone H3K36 methyltransferase activity 6/3674 13/18639 0.461538461538462 2.34148486244295 0.0280407883301984 0.136343253402632 GO:0005178 integrin binding 42/3674 161/18639 0.260869565217391 1.32344796572862 0.0289807385748497 0.140404877860824 GO:0008327 methyl-CpG binding 11/3674 31/18639 0.354838709677419 1.80017384585667 0.0295375102137881 0.142587549305409 GO:0004620 phospholipase activity 30/3674 109/18639 0.275229357798165 1.39629831246598 0.0300250037644935 0.14292968638145 GO:0042054 histone methyltransferase activity 20/3674 67/18639 0.298507462686567 1.51439319461484 0.030811265332116 0.14292968638145 GO:0050840 extracellular matrix binding 20/3674 67/18639 0.298507462686567 1.51439319461484 0.030811265332116 0.14292968638145 GO:0005154 epidermal growth factor receptor binding 12/3674 35/18639 0.342857142857143 1.73938875495762 0.030864557137082 0.14292968638145 GO:0140566 histone reader activity 12/3674 35/18639 0.342857142857143 1.73938875495762 0.030864557137082 0.14292968638145 GO:0005131 growth hormone receptor binding 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0008239 dipeptidyl-peptidase activity 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0035374 chondroitin sulfate binding 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0042975 peroxisome proliferator activated receptor binding 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0045322 unmethylated CpG binding 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0140999 histone H3K4 trimethyltransferase activity 5/3674 10/18639 0.5 2.53660860097986 0.0308864448961404 0.14292968638145 GO:0004713 protein tyrosine kinase activity 37/3674 140/18639 0.264285714285714 1.3407788319465 0.0320200629677382 0.147666407225789 GO:0016597 amino acid binding 16/3674 51/18639 0.313725490196078 1.59159755355599 0.0323861190503256 0.148843053991565 GO:0043177 organic acid binding 48/3674 189/18639 0.253968253968254 1.28843611478342 0.0326817664422746 0.149215351324491 GO:0042625 ATPase-coupled ion transmembrane transporter activity 9/3674 24/18639 0.375 1.90245645073489 0.0331158322131985 0.149215351324491 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 9/3674 24/18639 0.375 1.90245645073489 0.0331158322131985 0.149215351324491 GO:0046961 proton-transporting ATPase activity, rotational mechanism 9/3674 24/18639 0.375 1.90245645073489 0.0331158322131985 0.149215351324491 GO:0050431 transforming growth factor beta binding 9/3674 24/18639 0.375 1.90245645073489 0.0331158322131985 0.149215351324491 GO:0048306 calcium-dependent protein binding 23/3674 80/18639 0.2875 1.45854994556342 0.033134258341802 0.149215351324491 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 7/3674 17/18639 0.411764705882353 2.08897178904224 0.0349629397861395 0.155436611451497 GO:0008484 sulfuric ester hydrolase activity 7/3674 17/18639 0.411764705882353 2.08897178904224 0.0349629397861395 0.155436611451497 GO:0030169 low-density lipoprotein particle binding 7/3674 17/18639 0.411764705882353 2.08897178904224 0.0349629397861395 0.155436611451497 GO:0008013 beta-catenin binding 29/3674 106/18639 0.273584905660377 1.38795564959275 0.0349790288065217 0.155436611451497 GO:0051019 mitogen-activated protein kinase binding 10/3674 28/18639 0.357142857142857 1.81186328641418 0.0355774338806224 0.157573981081833 GO:0071813 lipoprotein particle binding 11/3674 32/18639 0.34375 1.74391841317365 0.0372198214771707 0.163767214499551 GO:0071814 protein-lipid complex binding 11/3674 32/18639 0.34375 1.74391841317365 0.0372198214771707 0.163767214499551 GO:0030971 receptor tyrosine kinase binding 23/3674 81/18639 0.283950617283951 1.44054315611202 0.0379074626835581 0.166247761180833 GO:0030159 signaling receptor complex adaptor activity 16/3674 52/18639 0.307692307692308 1.5609899082953 0.0384821246633193 0.168218277844216 GO:0004532 RNA exonuclease activity 13/3674 40/18639 0.325 1.64879559063691 0.0387711954213055 0.168931637192831 GO:0001046 core promoter sequence-specific DNA binding 14/3674 44/18639 0.318181818181818 1.61420547335082 0.0389374496755507 0.169106982086049 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 8/3674 21/18639 0.380952380952381 1.93265417217513 0.0397458984834499 0.172061276660612 GO:0005545 1-phosphatidylinositol binding 6/3674 14/18639 0.428571428571429 2.17423594369702 0.0410618033092303 0.174936317590435 GO:0032454 histone H3K9 demethylase activity 6/3674 14/18639 0.428571428571429 2.17423594369702 0.0410618033092303 0.174936317590435 GO:0034236 protein kinase A catalytic subunit binding 6/3674 14/18639 0.428571428571429 2.17423594369702 0.0410618033092303 0.174936317590435 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 6/3674 14/18639 0.428571428571429 2.17423594369702 0.0410618033092303 0.174936317590435 GO:0042813 Wnt receptor activity 6/3674 14/18639 0.428571428571429 2.17423594369702 0.0410618033092303 0.174936317590435 GO:0016279 protein-lysine N-methyltransferase activity 20/3674 69/18639 0.289855072463768 1.47049773969847 0.0413744819873651 0.175710616541278 GO:0008094 ATP-dependent activity, acting on DNA 52/3674 210/18639 0.247619047619048 1.25622521191383 0.0417128879913552 0.176588945376652 GO:0003707 nuclear steroid receptor activity 9/3674 25/18639 0.36 1.8263581927055 0.0429498495042955 0.18125376740492 GO:0008276 protein methyltransferase activity 26/3674 95/18639 0.273684210526316 1.38845944474687 0.0438798817165674 0.18459812308349 GO:0005126 cytokine receptor binding 66/3674 275/18639 0.24 1.21757212847033 0.0447225463131217 0.187555178600654 GO:0004629 phospholipase C activity 10/3674 29/18639 0.344827586206897 1.74938524205507 0.0449974790988081 0.188120302026793 GO:0060590 ATPase regulator activity 15/3674 49/18639 0.306122448979592 1.5530256740693 0.0460808338961396 0.188414724093247 GO:0019956 chemokine binding 11/3674 33/18639 0.333333333333333 1.69107240065324 0.0461943098286699 0.188414724093247 GO:0046915 transition metal ion transmembrane transporter activity 14/3674 45/18639 0.311111111111111 1.57833424060969 0.0466007911718084 0.188414724093247 GO:0001727 lipid kinase activity 13/3674 41/18639 0.317073170731707 1.60858106403601 0.0468567611448364 0.188414724093247 GO:0016278 lysine N-methyltransferase activity 20/3674 70/18639 0.285714285714286 1.44949062913135 0.0475464756047434 0.188414724093247 GO:0002162 dystroglycan binding 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0005225 volume-sensitive anion channel activity 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0019107 myristoyltransferase activity 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0019215 intermediate filament binding 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0019864 IgG binding 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0032050 clathrin heavy chain binding 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0042608 T cell receptor binding 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0050786 RAGE receptor binding 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0097493 structural molecule activity conferring elasticity 5/3674 11/18639 0.454545454545455 2.3060078190726 0.0476123845658744 0.188414724093247 GO:0016854 racemase and epimerase activity 7/3674 18/18639 0.388888888888889 1.97291780076211 0.0477354740623725 0.188414724093247 GO:0050811 GABA receptor binding 7/3674 18/18639 0.388888888888889 1.97291780076211 0.0477354740623725 0.188414724093247 GO:0070064 proline-rich region binding 7/3674 18/18639 0.388888888888889 1.97291780076211 0.0477354740623725 0.188414724093247 GO:0016757 glycosyltransferase activity 64/3674 267/18639 0.239700374531835 1.21605206339109 0.0485066960081256 0.190897319773914 GO:0140104 molecular carrier activity 60/3674 249/18639 0.240963855421687 1.22246197637584 0.0499027212919057 0.19581711103432 GO:0061980 regulatory RNA binding 17/3674 58/18639 0.293103448275862 1.48697745574681 0.0517825314899166 0.202601041572793 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 16/3674 54/18639 0.296296296296296 1.50317546724732 0.0530720066042936 0.206442414095542 GO:0140463 chromatin-protein adaptor activity 16/3674 54/18639 0.296296296296296 1.50317546724732 0.0530720066042936 0.206442414095542 GO:0008157 protein phosphatase 1 binding 9/3674 26/18639 0.346153846153846 1.75611364683221 0.0545641882124002 0.209814156392668 GO:0034237 protein kinase A regulatory subunit binding 9/3674 26/18639 0.346153846153846 1.75611364683221 0.0545641882124002 0.209814156392668 GO:0070412 R-SMAD binding 9/3674 26/18639 0.346153846153846 1.75611364683221 0.0545641882124002 0.209814156392668 GO:0097602 cullin family protein binding 9/3674 26/18639 0.346153846153846 1.75611364683221 0.0545641882124002 0.209814156392668 GO:0030276 clathrin binding 14/3674 46/18639 0.304347826086957 1.54402262668339 0.0552561292273137 0.211264174994458 GO:0030291 protein serine/threonine kinase inhibitor activity 14/3674 46/18639 0.304347826086957 1.54402262668339 0.0552561292273137 0.211264174994458 GO:0019894 kinesin binding 13/3674 42/18639 0.30952380952381 1.57028151489229 0.0560378334583364 0.213039015583817 GO:0035198 miRNA binding 13/3674 42/18639 0.30952380952381 1.57028151489229 0.0560378334583364 0.213039015583817 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 12/3674 38/18639 0.315789473684211 1.60206859009254 0.0565040627658392 0.213721020788386 GO:0030332 cyclin binding 11/3674 34/18639 0.323529411764706 1.64133497710461 0.0565357394782989 0.213721020788386 GO:0061578 K63-linked deubiquitinase activity 6/3674 15/18639 0.4 2.02928688078389 0.057327721248555 0.21610618515607 GO:0008234 cysteine-type peptidase activity 46/3674 187/18639 0.245989304812834 1.24795717267458 0.0580402773824047 0.218179418059348 GO:0005229 intracellularly calcium-gated chloride channel activity 7/3674 19/18639 0.368421052631579 1.86908002177463 0.063121367212589 0.23530242999804 GO:0005520 insulin-like growth factor binding 7/3674 19/18639 0.368421052631579 1.86908002177463 0.063121367212589 0.23530242999804 GO:0141147 intracellularly calcium-gated channel activity 7/3674 19/18639 0.368421052631579 1.86908002177463 0.063121367212589 0.23530242999804 GO:0015101 organic cation transmembrane transporter activity 22/3674 81/18639 0.271604938271605 1.37791084497671 0.0646561526371808 0.240356113127692 GO:0005516 calmodulin binding 50/3674 207/18639 0.241545893719807 1.22541478308206 0.0658178307341181 0.243998698467366 GO:0004712 protein serine/threonine/tyrosine kinase activity 13/3674 43/18639 0.302325581395349 1.53376334012736 0.0663609981894333 0.244776567044286 GO:0008171 O-methyltransferase activity 8/3674 23/18639 0.347826086956522 1.76459728763816 0.0664055634141023 0.244776567044286 GO:0001671 ATPase activator activity 9/3674 27/18639 0.333333333333333 1.69107240065324 0.0680371178560407 0.244776567044286 GO:0005385 zinc ion transmembrane transporter activity 9/3674 27/18639 0.333333333333333 1.69107240065324 0.0680371178560407 0.244776567044286 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 9/3674 27/18639 0.333333333333333 1.69107240065324 0.0680371178560407 0.244776567044286 GO:0005025 transforming growth factor beta receptor activity, type I 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0005026 transforming growth factor beta receptor activity, type II 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0008603 cAMP-dependent protein kinase regulator activity 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0016361 activin receptor activity, type I 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0016362 activin receptor activity, type II 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0017002 activin receptor activity 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0097677 STAT family protein binding 5/3674 12/18639 0.416666666666667 2.11384050081655 0.068719141266349 0.244776567044286 GO:0001098 basal transcription machinery binding 17/3674 60/18639 0.283333333333333 1.43741154055525 0.0687636108611741 0.244776567044286 GO:0001099 basal RNA polymerase II transcription machinery binding 17/3674 60/18639 0.283333333333333 1.43741154055525 0.0687636108611741 0.244776567044286 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 17/3674 60/18639 0.283333333333333 1.43741154055525 0.0687636108611741 0.244776567044286 GO:0051015 actin filament binding 50/3674 209/18639 0.239234449760766 1.21368832582768 0.0756364854191371 0.268529532890164 GO:0019783 ubiquitin-like protein peptidase activity 32/3674 127/18639 0.251968503937008 1.27829094852528 0.0768523638131607 0.269525581154387 GO:0004708 MAP kinase kinase activity 6/3674 16/18639 0.375 1.90245645073489 0.0769212351580702 0.269525581154387 GO:0005024 transforming growth factor beta receptor activity 6/3674 16/18639 0.375 1.90245645073489 0.0769212351580702 0.269525581154387 GO:0005159 insulin-like growth factor receptor binding 6/3674 16/18639 0.375 1.90245645073489 0.0769212351580702 0.269525581154387 GO:0070411 I-SMAD binding 6/3674 16/18639 0.375 1.90245645073489 0.0769212351580702 0.269525581154387 GO:0005543 phospholipid binding 111/3674 497/18639 0.223340040241449 1.13305253403929 0.0775167934934277 0.270905043927552 GO:0071949 FAD binding 12/3674 40/18639 0.3 1.52196516058791 0.0798371257577209 0.278289409784056 GO:0033218 amide binding 58/3674 247/18639 0.234817813765182 1.1912817721201 0.080050591814414 0.278310606774465 GO:0016004 phospholipase activator activity 7/3674 20/18639 0.35 1.7756260206859 0.0811798648794012 0.281507438419009 GO:0000993 RNA polymerase II complex binding 11/3674 36/18639 0.305555555555556 1.5501497005988 0.0815307488929002 0.281995528387299 GO:0052689 carboxylic ester hydrolase activity 24/3674 92/18639 0.260869565217391 1.32344796572862 0.0825388631530971 0.284748468769811 GO:0019957 C-C chemokine binding 8/3674 24/18639 0.333333333333333 1.69107240065324 0.0830504290145544 0.285047764034609 GO:0048027 mRNA 5'-UTR binding 8/3674 24/18639 0.333333333333333 1.69107240065324 0.0830504290145544 0.285047764034609 GO:0101005 deubiquitinase activity 29/3674 115/18639 0.252173913043478 1.27933303353767 0.087885073393212 0.300871858402272 GO:0000287 magnesium ion binding 54/3674 230/18639 0.234782608695652 1.19110316915576 0.0886398192116604 0.302683555679512 GO:0004527 exonuclease activity 22/3674 84/18639 0.261904761904762 1.3286997433704 0.0901853749867566 0.307179627492963 GO:0005338 nucleotide-sugar transmembrane transporter activity 5/3674 13/18639 0.384615384615385 1.95123738536912 0.0941431118514431 0.316641744623149 GO:0017154 semaphorin receptor activity 5/3674 13/18639 0.384615384615385 1.95123738536912 0.0941431118514431 0.316641744623149 GO:0035325 Toll-like receptor binding 5/3674 13/18639 0.384615384615385 1.95123738536912 0.0941431118514431 0.316641744623149 GO:0070123 transforming growth factor beta receptor activity, type III 5/3674 13/18639 0.384615384615385 1.95123738536912 0.0941431118514431 0.316641744623149 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 5/3674 13/18639 0.384615384615385 1.95123738536912 0.0941431118514431 0.316641744623149 GO:0005507 copper ion binding 17/3674 63/18639 0.26984126984127 1.36896337195738 0.100620747175824 0.333605783236754 GO:0016417 S-acyltransferase activity 9/3674 29/18639 0.310344827586207 1.57444671784957 0.100699632974648 0.333605783236754 GO:0106222 lncRNA binding 9/3674 29/18639 0.310344827586207 1.57444671784957 0.100699632974648 0.333605783236754 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 7/3674 21/18639 0.333333333333333 1.69107240065324 0.101896848077377 0.333605783236754 GO:0051010 microtubule plus-end binding 7/3674 21/18639 0.333333333333333 1.69107240065324 0.101896848077377 0.333605783236754 GO:0140312 cargo adaptor activity 7/3674 21/18639 0.333333333333333 1.69107240065324 0.101896848077377 0.333605783236754 GO:0000030 mannosyltransferase activity 8/3674 25/18639 0.32 1.62342950462711 0.101921289960558 0.333605783236754 GO:0008483 transaminase activity 8/3674 25/18639 0.32 1.62342950462711 0.101921289960558 0.333605783236754 GO:0019706 protein-cysteine S-palmitoyltransferase activity 8/3674 25/18639 0.32 1.62342950462711 0.101921289960558 0.333605783236754 GO:0019707 protein-cysteine S-acyltransferase activity 8/3674 25/18639 0.32 1.62342950462711 0.101921289960558 0.333605783236754 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 8/3674 25/18639 0.32 1.62342950462711 0.101921289960558 0.333605783236754 GO:0001618 virus receptor activity 21/3674 81/18639 0.259259259259259 1.31527853384141 0.104676918190021 0.341791786401479 GO:0004843 cysteine-type deubiquitinase activity 27/3674 108/18639 0.25 1.26830430048993 0.105222680455598 0.342739896047116 GO:0032934 sterol binding 18/3674 68/18639 0.264705882352941 1.34291043581287 0.107959268463646 0.35080227186008 GO:0003724 RNA helicase activity 20/3674 77/18639 0.25974025974026 1.31771875375577 0.109632367555255 0.355378350867516 GO:0005109 frizzled binding 11/3674 38/18639 0.289473684210526 1.4685628742515 0.112430378260158 0.360526834255304 GO:0042162 telomeric DNA binding 11/3674 38/18639 0.289473684210526 1.4685628742515 0.112430378260158 0.360526834255304 GO:0042887 amide transmembrane transporter activity 11/3674 38/18639 0.289473684210526 1.4685628742515 0.112430378260158 0.360526834255304 GO:0005048 signal sequence binding 14/3674 51/18639 0.274509803921569 1.39264785936149 0.114564294563845 0.360526834255304 GO:0043539 protein serine/threonine kinase activator activity 19/3674 73/18639 0.26027397260274 1.32042639503061 0.114864139076267 0.360526834255304 GO:0140272 exogenous protein binding 21/3674 82/18639 0.25609756097561 1.29923855172139 0.115742535882948 0.360526834255304 GO:0004382 GDP phosphatase activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0004445 inositol-polyphosphate 5-phosphatase activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0004862 cAMP-dependent protein kinase inhibitor activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0005345 purine nucleobase transmembrane transporter activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0005381 iron ion transmembrane transporter activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0016868 intramolecular phosphotransferase activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0030957 Tat protein binding 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0043422 protein kinase B binding 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0051864 histone H3K36 demethylase activity 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0099122 RNA polymerase II C-terminal domain binding 4/3674 10/18639 0.4 2.02928688078389 0.115787679257851 0.360526834255304 GO:0098531 ligand-modulated transcription factor activity 16/3674 60/18639 0.266666666666667 1.35285792052259 0.118286044410145 0.367453406477811 GO:0005504 fatty acid binding 13/3674 47/18639 0.276595744680851 1.40323028990375 0.119580132639261 0.368911581613535 GO:0061749 forked DNA-dependent helicase activity 13/3674 47/18639 0.276595744680851 1.40323028990375 0.119580132639261 0.368911581613535 GO:1990518 single-stranded 3'-5' DNA helicase activity 13/3674 47/18639 0.276595744680851 1.40323028990375 0.119580132639261 0.368911581613535 GO:0004435 phosphatidylinositol phospholipase C activity 8/3674 26/18639 0.307692307692308 1.5609899082953 0.122968890737518 0.377079819510096 GO:0050750 low-density lipoprotein particle receptor binding 8/3674 26/18639 0.307692307692308 1.5609899082953 0.122968890737518 0.377079819510096 GO:0004705 JUN kinase activity 5/3674 14/18639 0.357142857142857 1.81186328641418 0.123632727708228 0.377079819510096 GO:0016530 metallochaperone activity 5/3674 14/18639 0.357142857142857 1.81186328641418 0.123632727708228 0.377079819510096 GO:0098821 BMP receptor activity 5/3674 14/18639 0.357142857142857 1.81186328641418 0.123632727708228 0.377079819510096 GO:0016887 ATP hydrolysis activity 92/3674 417/18639 0.220623501199041 1.11927094143955 0.124120419237856 0.377708849472114 GO:0003924 GTPase activity 74/3674 331/18639 0.223564954682779 1.13419357385202 0.125683113823132 0.379510453024098 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 6/3674 18/18639 0.333333333333333 1.69107240065324 0.125843630101135 0.379510453024098 GO:0008409 5'-3' exonuclease activity 6/3674 18/18639 0.333333333333333 1.69107240065324 0.125843630101135 0.379510453024098 GO:0017075 syntaxin-1 binding 6/3674 18/18639 0.333333333333333 1.69107240065324 0.125843630101135 0.379510453024098 GO:0017124 SH3 domain binding 28/3674 115/18639 0.243478260869565 1.23521810134671 0.129059365795719 0.388335580488465 GO:0008186 ATP-dependent activity, acting on RNA 20/3674 79/18639 0.253164556962025 1.28435878530626 0.133825716514931 0.400879713310353 GO:0033293 monocarboxylic acid binding 20/3674 79/18639 0.253164556962025 1.28435878530626 0.133825716514931 0.400879713310353 GO:1902936 phosphatidylinositol bisphosphate binding 27/3674 111/18639 0.243243243243243 1.23402580588209 0.13528110592559 0.402531493807339 GO:0000175 3'-5'-RNA exonuclease activity 10/3674 35/18639 0.285714285714286 1.44949062913135 0.135472348121247 0.402531493807339 GO:0009378 four-way junction helicase activity 13/3674 48/18639 0.270833333333333 1.37399632553076 0.13587687533139 0.402531493807339 GO:0036121 double-stranded DNA helicase activity 13/3674 48/18639 0.270833333333333 1.37399632553076 0.13587687533139 0.402531493807339 GO:0043138 3'-5' DNA helicase activity 13/3674 48/18639 0.270833333333333 1.37399632553076 0.13587687533139 0.402531493807339 GO:0070273 phosphatidylinositol-4-phosphate binding 9/3674 31/18639 0.290322580645161 1.47286951024637 0.140864243239363 0.415472119620275 GO:0070325 lipoprotein particle receptor binding 9/3674 31/18639 0.290322580645161 1.47286951024637 0.140864243239363 0.415472119620275 GO:0008170 N-methyltransferase activity 24/3674 98/18639 0.244897959183673 1.24242053925544 0.143925035395036 0.423568854166971 GO:0005201 extracellular matrix structural constituent 39/3674 168/18639 0.232142857142857 1.17771113616922 0.147353225558563 0.432709034353593 GO:0003887 DNA-directed DNA polymerase activity 7/3674 23/18639 0.304347826086957 1.54402262668339 0.150905377435922 0.439093937965782 GO:0004602 glutathione peroxidase activity 7/3674 23/18639 0.304347826086957 1.54402262668339 0.150905377435922 0.439093937965782 GO:0016493 C-C chemokine receptor activity 7/3674 23/18639 0.304347826086957 1.54402262668339 0.150905377435922 0.439093937965782 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 7/3674 23/18639 0.304347826086957 1.54402262668339 0.150905377435922 0.439093937965782 GO:0016758 hexosyltransferase activity 45/3674 197/18639 0.228426395939086 1.15885672125983 0.153765016856671 0.439093937965782 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0015205 nucleobase transmembrane transporter activity 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0032794 GTPase activating protein binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0034056 estrogen response element binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0034713 type I transforming growth factor beta receptor binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0043522 leucine zipper domain binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0070990 snRNP binding 4/3674 11/18639 0.363636363636364 1.84480625525808 0.154744990510409 0.439093937965782 GO:0015245 fatty acid transmembrane transporter activity 6/3674 19/18639 0.315789473684211 1.60206859009254 0.154792366818926 0.439093937965782 GO:0042800 histone H3K4 methyltransferase activity 6/3674 19/18639 0.315789473684211 1.60206859009254 0.154792366818926 0.439093937965782 GO:0017116 single-stranded DNA helicase activity 15/3674 58/18639 0.258620689655172 1.31203893154131 0.155089811174203 0.439093937965782 GO:0015929 hexosaminidase activity 5/3674 15/18639 0.333333333333333 1.69107240065324 0.156785230938065 0.442028949409418 GO:0031005 filamin binding 5/3674 15/18639 0.333333333333333 1.69107240065324 0.156785230938065 0.442028949409418 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 14/3674 54/18639 0.259259259259259 1.31527853384141 0.163204772564676 0.458316533320783 GO:0043425 bHLH transcription factor binding 9/3674 32/18639 0.28125 1.42684233805117 0.163586899747135 0.458316533320783 GO:0120015 sterol transfer activity 9/3674 32/18639 0.28125 1.42684233805117 0.163586899747135 0.458316533320783 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 21/3674 86/18639 0.244186046511628 1.23880885164133 0.166812333747478 0.466379483102325 GO:0015175 neutral L-amino acid transmembrane transporter activity 11/3674 41/18639 0.268292682926829 1.36110705418431 0.169534080496119 0.47300360920123 GO:0046875 ephrin receptor binding 8/3674 28/18639 0.285714285714286 1.44949062913135 0.171172178519637 0.475329190912165 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 8/3674 28/18639 0.285714285714286 1.44949062913135 0.171172178519637 0.475329190912165 GO:0001786 phosphatidylserine binding 15/3674 59/18639 0.254237288135593 1.28980098354908 0.172138589257312 0.475329190912165 GO:0004879 nuclear receptor activity 15/3674 59/18639 0.254237288135593 1.28980098354908 0.172138589257312 0.475329190912165 GO:0031593 polyubiquitin modification-dependent protein binding 15/3674 59/18639 0.254237288135593 1.28980098354908 0.172138589257312 0.475329190912165 GO:0001091 RNA polymerase II general transcription initiation factor binding 7/3674 24/18639 0.291666666666667 1.47968835057158 0.178845650315309 0.489818087190091 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 7/3674 24/18639 0.291666666666667 1.47968835057158 0.178845650315309 0.489818087190091 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 7/3674 24/18639 0.291666666666667 1.47968835057158 0.178845650315309 0.489818087190091 GO:0060229 lipase activator activity 7/3674 24/18639 0.291666666666667 1.47968835057158 0.178845650315309 0.489818087190091 GO:0035401 histone H3Y41 kinase activity 27/3674 115/18639 0.234782608695652 1.19110316915576 0.182504761220995 0.497807702354828 GO:0140801 histone H2AXY142 kinase activity 27/3674 115/18639 0.234782608695652 1.19110316915576 0.182504761220995 0.497807702354828 GO:0051087 protein-folding chaperone binding 31/3674 134/18639 0.23134328358209 1.1736547258265 0.185263796052117 0.504308345440042 GO:0005326 neurotransmitter transmembrane transporter activity 6/3674 20/18639 0.3 1.52196516058791 0.186340581935865 0.504926858251871 GO:0031418 L-ascorbic acid binding 6/3674 20/18639 0.3 1.52196516058791 0.186340581935865 0.504926858251871 GO:0043178 alcohol binding 22/3674 92/18639 0.239130434782609 1.21316063525124 0.186619762811422 0.504926858251871 GO:0030296 protein tyrosine kinase activator activity 9/3674 33/18639 0.272727272727273 1.38360469144356 0.187916233405731 0.507411640302799 GO:0048487 beta-tubulin binding 11/3674 42/18639 0.261904761904762 1.3286997433704 0.191204567129808 0.51500254558983 GO:0030544 Hsp70 protein binding 13/3674 51/18639 0.254901960784314 1.29317301226424 0.191495248335384 0.51500254558983 GO:0005324 long-chain fatty acid transmembrane transporter activity 5/3674 16/18639 0.3125 1.58538037561241 0.193087047201698 0.51500254558983 GO:0031435 mitogen-activated protein kinase kinase kinase binding 5/3674 16/18639 0.3125 1.58538037561241 0.193087047201698 0.51500254558983 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 5/3674 16/18639 0.3125 1.58538037561241 0.193087047201698 0.51500254558983 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 5/3674 16/18639 0.3125 1.58538037561241 0.193087047201698 0.51500254558983 GO:0015631 tubulin binding 83/3674 385/18639 0.215584415584416 1.09370656561729 0.19509154669177 0.51500254558983 GO:0004875 complement receptor activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0005095 GTPase inhibitor activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0005247 voltage-gated chloride channel activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0008504 monoamine transmembrane transporter activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0035014 phosphatidylinositol 3-kinase regulator activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0035251 UDP-glucosyltransferase activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0070410 co-SMAD binding 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0070679 inositol 1,4,5 trisphosphate binding 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 4/3674 12/18639 0.333333333333333 1.69107240065324 0.197757915132438 0.51500254558983 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 8/3674 29/18639 0.275862068965517 1.39950819364406 0.198018862536775 0.51500254558983 GO:0051861 glycolipid binding 8/3674 29/18639 0.275862068965517 1.39950819364406 0.198018862536775 0.51500254558983 GO:0042626 ATPase-coupled transmembrane transporter activity 23/3674 98/18639 0.23469387755102 1.19065301678646 0.206313910567476 0.535208756014381 GO:0031072 heat shock protein binding 30/3674 131/18639 0.229007633587786 1.16180546609765 0.20658579405026 0.535208756014381 GO:0008139 nuclear localization sequence binding 7/3674 25/18639 0.28 1.42050081654872 0.208760679342156 0.538763137840719 GO:0019211 phosphatase activator activity 7/3674 25/18639 0.28 1.42050081654872 0.208760679342156 0.538763137840719 GO:0003727 single-stranded RNA binding 21/3674 89/18639 0.235955056179775 1.19705124990061 0.211861525559583 0.545716252017198 GO:0052866 phosphatidylinositol phosphate phosphatase activity 9/3674 34/18639 0.264705882352941 1.34291043581287 0.213705013258191 0.549410206499028 GO:0008017 microtubule binding 60/3674 276/18639 0.217391304347826 1.10287330477385 0.216849338215014 0.556427938593784 GO:0010314 phosphatidylinositol-5-phosphate binding 6/3674 21/18639 0.285714285714286 1.44949062913135 0.22011807547926 0.562663728177461 GO:0035613 RNA stem-loop binding 6/3674 21/18639 0.285714285714286 1.44949062913135 0.22011807547926 0.562663728177461 GO:0015932 nucleobase-containing compound transmembrane transporter activity 14/3674 57/18639 0.245614035087719 1.24605334784976 0.220750576223847 0.563207743901907 GO:0016769 transferase activity, transferring nitrogenous groups 8/3674 30/18639 0.266666666666667 1.35285792052259 0.226436400841234 0.576473685318333 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 10/3674 39/18639 0.256410256410256 1.30082492357941 0.22680931881377 0.576473685318333 GO:0015291 secondary active transmembrane transporter activity 62/3674 287/18639 0.21602787456446 1.09595632934321 0.228546399276295 0.57979067642493 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:0015278 intracellularly gated calcium channel activity 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:0017110 nucleoside diphosphate phosphatase activity 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:0038191 neuropilin binding 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:0070403 NAD+ binding 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:1990226 histone methyltransferase binding 5/3674 17/18639 0.294117647058824 1.49212270645874 0.23195349266565 0.580749229771087 GO:0050660 flavin adenine dinucleotide binding 20/3674 86/18639 0.232558139534884 1.17981795394412 0.239969750921424 0.593814148615038 GO:0001637 G protein-coupled chemoattractant receptor activity 7/3674 26/18639 0.269230769230769 1.36586616975839 0.240368180407023 0.593814148615038 GO:0004112 cyclic-nucleotide phosphodiesterase activity 7/3674 26/18639 0.269230769230769 1.36586616975839 0.240368180407023 0.593814148615038 GO:0004529 DNA exonuclease activity 7/3674 26/18639 0.269230769230769 1.36586616975839 0.240368180407023 0.593814148615038 GO:0004950 chemokine receptor activity 7/3674 26/18639 0.269230769230769 1.36586616975839 0.240368180407023 0.593814148615038 GO:0005112 Notch binding 7/3674 26/18639 0.269230769230769 1.36586616975839 0.240368180407023 0.593814148615038 GO:0005343 organic acid:sodium symporter activity 9/3674 35/18639 0.257142857142857 1.30454156621821 0.24078555119021 0.593814148615038 GO:0043021 ribonucleoprotein complex binding 39/3674 177/18639 0.220338983050847 1.11782751907587 0.243398031774394 0.593814148615038 GO:0005035 death receptor activity 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0008035 high-density lipoprotein particle binding 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0035673 oligopeptide transmembrane transporter activity 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0043560 insulin receptor substrate binding 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0045159 myosin II binding 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0097157 pre-mRNA intronic binding 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0140852 histone ubiquitin ligase activity 4/3674 13/18639 0.307692307692308 1.5609899082953 0.243808938812881 0.593814148615038 GO:0072341 modified amino acid binding 21/3674 91/18639 0.230769230769231 1.17074243122147 0.244738071939397 0.594997269099041 GO:0061791 GTPase motor activity 10/3674 40/18639 0.25 1.26830430048993 0.252702276142712 0.612141614771696 GO:1990606 membrane scission GTPase motor activity 10/3674 40/18639 0.25 1.26830430048993 0.252702276142712 0.612141614771696 GO:0030246 carbohydrate binding 60/3674 280/18639 0.214285714285714 1.08711797184851 0.254448292172419 0.613251531511618 GO:0008093 cytoskeletal anchor activity 6/3674 22/18639 0.272727272727273 1.38360469144356 0.255716837758871 0.613251531511618 GO:0015377 chloride:monoatomic cation symporter activity 6/3674 22/18639 0.272727272727273 1.38360469144356 0.255716837758871 0.613251531511618 GO:0030021 extracellular matrix structural constituent conferring compression resistance 6/3674 22/18639 0.272727272727273 1.38360469144356 0.255716837758871 0.613251531511618 GO:0070034 telomerase RNA binding 6/3674 22/18639 0.272727272727273 1.38360469144356 0.255716837758871 0.613251531511618 GO:0015485 cholesterol binding 13/3674 54/18639 0.240740740740741 1.22133006713845 0.255902278425116 0.613251531511618 GO:0015297 antiporter activity 30/3674 135/18639 0.222222222222222 1.12738160043549 0.26095548256755 0.624246448494924 GO:0140303 intramembrane lipid transporter activity 11/3674 45/18639 0.244444444444444 1.24011976047904 0.262779871037725 0.627492147566952 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 14/3674 59/18639 0.23728813559322 1.20381425131248 0.263266119608893 0.627536647451394 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 9/3674 36/18639 0.25 1.26830430048993 0.268974362568539 0.637744866726111 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 9/3674 36/18639 0.25 1.26830430048993 0.268974362568539 0.637744866726111 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 9/3674 36/18639 0.25 1.26830430048993 0.268974362568539 0.637744866726111 GO:0015172 acidic amino acid transmembrane transporter activity 5/3674 18/18639 0.277777777777778 1.40922700054437 0.272764978267387 0.643322672820445 GO:0035615 clathrin adaptor activity 5/3674 18/18639 0.277777777777778 1.40922700054437 0.272764978267387 0.643322672820445 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 5/3674 18/18639 0.277777777777778 1.40922700054437 0.272764978267387 0.643322672820445 GO:0004683 calcium/calmodulin-dependent protein kinase activity 7/3674 27/18639 0.259259259259259 1.31527853384141 0.273362723156185 0.643601358729124 GO:0008168 methyltransferase activity 44/3674 204/18639 0.215686274509804 1.09422331806974 0.276443660187107 0.649715222366196 GO:0008374 O-acyltransferase activity 13/3674 55/18639 0.236363636363636 1.19912406591775 0.278942401036792 0.654441787047859 GO:0015293 symporter activity 32/3674 146/18639 0.219178082191781 1.11193801686788 0.28019562510987 0.656234779925734 GO:0031491 nucleosome binding 17/3674 74/18639 0.22972972972973 1.16546881666642 0.280916567904934 0.656777062941501 GO:0070717 poly-purine tract binding 8/3674 32/18639 0.25 1.26830430048993 0.287071872847381 0.664662666980321 GO:0051117 ATPase binding 19/3674 84/18639 0.226190476190476 1.14751341472898 0.2900166359476 0.664662666980321 GO:0180051 translation factor activity 19/3674 84/18639 0.226190476190476 1.14751341472898 0.2900166359476 0.664662666980321 GO:0016741 transferase activity, transferring one-carbon groups 46/3674 215/18639 0.213953488372093 1.08543251762859 0.291149322589634 0.664662666980321 GO:0004065 arylsulfatase activity 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0008174 mRNA methyltransferase activity 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0008494 translation activator activity 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0015926 glucosidase activity 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0019763 immunoglobulin receptor activity 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0042043 neurexin family protein binding 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0046030 inositol trisphosphate phosphatase activity 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0070742 C2H2 zinc finger domain binding 4/3674 14/18639 0.285714285714286 1.44949062913135 0.291879423254742 0.664662666980321 GO:0005283 amino acid:sodium symporter activity 6/3674 23/18639 0.260869565217391 1.32344796572862 0.292709117872854 0.664662666980321 GO:0042171 lysophosphatidic acid acyltransferase activity 6/3674 23/18639 0.260869565217391 1.32344796572862 0.292709117872854 0.664662666980321 GO:0043274 phospholipase binding 6/3674 23/18639 0.260869565217391 1.32344796572862 0.292709117872854 0.664662666980321 GO:0071617 lysophospholipid acyltransferase activity 6/3674 23/18639 0.260869565217391 1.32344796572862 0.292709117872854 0.664662666980321 GO:0140103 catalytic activity, acting on a glycoprotein 6/3674 23/18639 0.260869565217391 1.32344796572862 0.292709117872854 0.664662666980321 GO:0008028 monocarboxylic acid transmembrane transporter activity 16/3674 70/18639 0.228571428571429 1.15959250330508 0.296585589442177 0.672327467958448 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 36/3674 167/18639 0.215568862275449 1.09362766030269 0.301957610573399 0.683350950066612 GO:0170055 lipid transmembrane transporter activity 13/3674 56/18639 0.232142857142857 1.17771113616922 0.302606826343097 0.683667274330701 GO:0016859 cis-trans isomerase activity 10/3674 42/18639 0.238095238095238 1.20790885760946 0.307132651108004 0.686027902888085 GO:0051879 Hsp90 protein binding 10/3674 42/18639 0.238095238095238 1.20790885760946 0.307132651108004 0.686027902888085 GO:0045499 chemorepellent activity 7/3674 28/18639 0.25 1.26830430048993 0.307426238035035 0.686027902888085 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0004090 carbonyl reductase (NADPH) activity 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0005031 tumor necrosis factor receptor activity 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0015643 toxic substance binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0035256 G protein-coupled glutamate receptor binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0043208 glycosphingolipid binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0043295 glutathione binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0050815 phosphoserine residue binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0070513 death domain binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0098505 G-rich strand telomeric DNA binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:1990763 arrestin family protein binding 3/3674 10/18639 0.3 1.52196516058791 0.313481972726634 0.686027902888085 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 5/3674 19/18639 0.263157894736842 1.33505715841045 0.314898053784695 0.686027902888085 GO:0005346 purine ribonucleotide transmembrane transporter activity 5/3674 19/18639 0.263157894736842 1.33505715841045 0.314898053784695 0.686027902888085 GO:0097001 ceramide binding 5/3674 19/18639 0.263157894736842 1.33505715841045 0.314898053784695 0.686027902888085 GO:0120227 acyl-CoA binding 5/3674 19/18639 0.263157894736842 1.33505715841045 0.314898053784695 0.686027902888085 GO:0005319 lipid transporter activity 38/3674 178/18639 0.213483146067416 1.08304636895769 0.3185955823896 0.692958300756634 GO:0005080 protein kinase C binding 12/3674 52/18639 0.230769230769231 1.17074243122147 0.321204189187367 0.697501653542794 GO:0000146 microfilament motor activity 9/3674 38/18639 0.236842105263158 1.20155144256941 0.327892120013963 0.7088667103399 GO:0043531 ADP binding 9/3674 38/18639 0.236842105263158 1.20155144256941 0.327892120013963 0.7088667103399 GO:0016209 antioxidant activity 19/3674 86/18639 0.22093023255814 1.12082705624691 0.328988870791945 0.7088667103399 GO:0004806 triacylglycerol lipase activity 6/3674 24/18639 0.25 1.26830430048993 0.330663607058702 0.7088667103399 GO:0005540 hyaluronic acid binding 6/3674 24/18639 0.25 1.26830430048993 0.330663607058702 0.7088667103399 GO:0015295 solute:proton symporter activity 6/3674 24/18639 0.25 1.26830430048993 0.330663607058702 0.7088667103399 GO:0030215 semaphorin receptor binding 6/3674 24/18639 0.25 1.26830430048993 0.330663607058702 0.7088667103399 GO:0070840 dynein complex binding 6/3674 24/18639 0.25 1.26830430048993 0.330663607058702 0.7088667103399 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 20/3674 91/18639 0.21978021978022 1.1149927916395 0.331995510639873 0.710586882422185 GO:0008375 acetylglucosaminyltransferase activity 10/3674 43/18639 0.232558139534884 1.17981795394412 0.335341079610587 0.716604663753835 GO:0004559 alpha-mannosidase activity 4/3674 15/18639 0.266666666666667 1.35285792052259 0.34100458409717 0.724095176991143 GO:0005402 carbohydrate:monoatomic cation symporter activity 4/3674 15/18639 0.266666666666667 1.35285792052259 0.34100458409717 0.724095176991143 GO:0005523 tropomyosin binding 4/3674 15/18639 0.266666666666667 1.35285792052259 0.34100458409717 0.724095176991143 GO:0140776 protein-containing complex destabilizing activity 4/3674 15/18639 0.266666666666667 1.35285792052259 0.34100458409717 0.724095176991143 GO:0035250 UDP-galactosyltransferase activity 7/3674 29/18639 0.241379310344828 1.22456966943855 0.342237675693571 0.72556549886378 GO:0015294 solute:monoatomic cation symporter activity 25/3674 116/18639 0.21551724137931 1.09336577628442 0.343679118579186 0.727472203680232 GO:0004540 RNA nuclease activity 26/3674 121/18639 0.214876033057851 1.09011278719796 0.345508276331446 0.729044193139624 GO:0051082 unfolded protein binding 26/3674 121/18639 0.214876033057851 1.09011278719796 0.345508276331446 0.729044193139624 GO:0004864 protein phosphatase inhibitor activity 12/3674 53/18639 0.226415094339623 1.14865295138711 0.346848475135049 0.730723161116539 GO:0051427 hormone receptor binding 8/3674 34/18639 0.235294117647059 1.19369816516699 0.351139112610406 0.736821377070899 GO:0090482 vitamin transmembrane transporter activity 8/3674 34/18639 0.235294117647059 1.19369816516699 0.351139112610406 0.736821377070899 GO:0008408 3'-5' exonuclease activity 13/3674 58/18639 0.224137931034483 1.1371004073358 0.351390224534557 0.736821377070899 GO:1901682 sulfur compound transmembrane transporter activity 14/3674 63/18639 0.222222222222222 1.12738160043549 0.355336376990122 0.743933569299133 GO:0016408 C-acyltransferase activity 5/3674 20/18639 0.25 1.26830430048993 0.357750544400971 0.746658212420067 GO:0140939 histone H4 methyltransferase activity 5/3674 20/18639 0.25 1.26830430048993 0.357750544400971 0.746658212420067 GO:0005548 phospholipid transporter activity 15/3674 68/18639 0.220588235294118 1.11909202984406 0.358795856305889 0.74767707944488 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 38/3674 181/18639 0.209944751381215 1.06509532416834 0.360008415222037 0.749040764694533 GO:0043014 alpha-tubulin binding 10/3674 44/18639 0.227272727272727 1.1530039095363 0.363987270029819 0.756146929380831 GO:0019199 transmembrane receptor protein kinase activity 17/3674 78/18639 0.217948717948718 1.1057011850425 0.364569353982038 0.756185584302774 GO:0008135 translation factor activity, RNA binding 18/3674 83/18639 0.216867469879518 1.10021577873825 0.366999519776566 0.760051474598998 GO:0035254 glutamate receptor binding 11/3674 49/18639 0.224489795918367 1.13888549431749 0.368783813997677 0.760755613525012 GO:0015296 monoatomic anion:monoatomic cation symporter activity 6/3674 25/18639 0.24 1.21757212847033 0.369159268442874 0.760755613525012 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 6/3674 25/18639 0.24 1.21757212847033 0.369159268442874 0.760755613525012 GO:0050661 NADP binding 12/3674 54/18639 0.222222222222222 1.12738160043549 0.372833102766458 0.760755613525012 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/3674 11/18639 0.272727272727273 1.38360469144356 0.373008341057718 0.760755613525012 GO:0019203 carbohydrate phosphatase activity 3/3674 11/18639 0.272727272727273 1.38360469144356 0.373008341057718 0.760755613525012 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/3674 11/18639 0.272727272727273 1.38360469144356 0.373008341057718 0.760755613525012 GO:0045294 alpha-catenin binding 3/3674 11/18639 0.272727272727273 1.38360469144356 0.373008341057718 0.760755613525012 GO:0140537 transcription regulator activator activity 3/3674 11/18639 0.272727272727273 1.38360469144356 0.373008341057718 0.760755613525012 GO:1900750 oligopeptide binding 3/3674 11/18639 0.272727272727273 1.38360469144356 0.373008341057718 0.760755613525012 GO:0015459 potassium channel regulator activity 13/3674 59/18639 0.220338983050847 1.11782751907587 0.376294862883114 0.766293939285491 GO:0008187 poly-pyrimidine tract binding 7/3674 30/18639 0.233333333333333 1.18375068045727 0.377481541952979 0.766384613163234 GO:0051721 protein phosphatase 2A binding 7/3674 30/18639 0.233333333333333 1.18375068045727 0.377481541952979 0.766384613163234 GO:0004536 DNA nuclease activity 14/3674 64/18639 0.21875 1.10976626292869 0.379285309889654 0.768883513401686 GO:0034061 DNA polymerase activity 8/3674 35/18639 0.228571428571429 1.15959250330508 0.383836464142316 0.776457948688216 GO:0003678 DNA helicase activity 16/3674 74/18639 0.216216216216216 1.09691182745075 0.384178895625168 0.776457948688216 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 9/3674 40/18639 0.225 1.14147387044094 0.388850255796013 0.776548931949273 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 9/3674 40/18639 0.225 1.14147387044094 0.388850255796013 0.776548931949273 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0015378 sodium:chloride symporter activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0015562 efflux transmembrane transporter activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0015923 mannosidase activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0022858 alanine transmembrane transporter activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0030275 LRR domain binding 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0140327 flippase activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0140328 floppase activity 4/3674 16/18639 0.25 1.26830430048993 0.390310429728995 0.776548931949273 GO:0005525 GTP binding 77/3674 378/18639 0.203703703703704 1.03343313373253 0.392883593533602 0.776548931949273 GO:0004715 non-membrane spanning protein tyrosine kinase activity 10/3674 45/18639 0.222222222222222 1.12738160043549 0.392903669741845 0.776548931949273 GO:0008009 chemokine activity 10/3674 45/18639 0.222222222222222 1.12738160043549 0.392903669741845 0.776548931949273 GO:0051539 4 iron, 4 sulfur cluster binding 10/3674 45/18639 0.222222222222222 1.12738160043549 0.392903669741845 0.776548931949273 GO:0141110 transporter inhibitor activity 10/3674 45/18639 0.222222222222222 1.12738160043549 0.392903669741845 0.776548931949273 GO:0015605 organophosphate ester transmembrane transporter activity 11/3674 50/18639 0.22 1.11610778443114 0.396242952927671 0.780848814726777 GO:0032813 tumor necrosis factor receptor superfamily binding 11/3674 50/18639 0.22 1.11610778443114 0.396242952927671 0.780848814726777 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 5/3674 21/18639 0.238095238095238 1.20790885760946 0.400760690939007 0.785139922978317 GO:0005123 death receptor binding 5/3674 21/18639 0.238095238095238 1.20790885760946 0.400760690939007 0.785139922978317 GO:0015174 basic amino acid transmembrane transporter activity 5/3674 21/18639 0.238095238095238 1.20790885760946 0.400760690939007 0.785139922978317 GO:0072542 protein phosphatase activator activity 5/3674 21/18639 0.238095238095238 1.20790885760946 0.400760690939007 0.785139922978317 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 13/3674 60/18639 0.216666666666667 1.09919706042461 0.401398023078021 0.785242196750298 GO:0120013 lipid transfer activity 14/3674 65/18639 0.215384615384615 1.09269293580671 0.403417147842392 0.787161101059528 GO:0004518 nuclease activity 43/3674 209/18639 0.205741626794258 1.04377196021181 0.403552039887448 0.787161101059528 GO:0008143 poly(A) binding 6/3674 26/18639 0.230769230769231 1.17074243122147 0.40779659485363 0.791987019238164 GO:0019865 immunoglobulin binding 6/3674 26/18639 0.230769230769231 1.17074243122147 0.40779659485363 0.791987019238164 GO:0030247 polysaccharide binding 6/3674 26/18639 0.230769230769231 1.17074243122147 0.40779659485363 0.791987019238164 GO:0019001 guanyl nucleotide binding 81/3674 400/18639 0.2025 1.02732648339684 0.412192091617446 0.7971965464104 GO:0032561 guanyl ribonucleotide binding 81/3674 400/18639 0.2025 1.02732648339684 0.412192091617446 0.7971965464104 GO:0016411 acylglycerol O-acyltransferase activity 7/3674 31/18639 0.225806451612903 1.14556517463607 0.412855141397338 0.7971965464104 GO:0017147 Wnt-protein binding 7/3674 31/18639 0.225806451612903 1.14556517463607 0.412855141397338 0.7971965464104 GO:0016798 hydrolase activity, acting on glycosyl bonds 27/3674 130/18639 0.207692307692308 1.05366818809933 0.414981118565794 0.800150375165654 GO:1901681 sulfur compound binding 56/3674 275/18639 0.203636363636364 1.03309150294452 0.41609430672049 0.801074421771784 GO:0004190 aspartic-type endopeptidase activity 8/3674 36/18639 0.222222222222222 1.12738160043549 0.41665420744911 0.801074421771784 GO:0017080 sodium channel regulator activity 9/3674 41/18639 0.219512195121951 1.11363304433262 0.419596373452343 0.805577014553711 GO:0019212 phosphatase inhibitor activity 12/3674 56/18639 0.214285714285714 1.08711797184851 0.425333795259477 0.814262415461081 GO:0030170 pyridoxal phosphate binding 12/3674 56/18639 0.214285714285714 1.08711797184851 0.425333795259477 0.814262415461081 GO:0017022 myosin binding 16/3674 76/18639 0.210526315789474 1.06804572672836 0.429233138584919 0.814589373874338 GO:0005165 neurotrophin receptor binding 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0016273 arginine N-methyltransferase activity 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0016274 protein-arginine N-methyltransferase activity 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0034452 dynactin binding 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0035197 siRNA binding 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0043047 single-stranded telomeric DNA binding 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0097371 MDM2/MDM4 family protein binding 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/3674 12/18639 0.25 1.26830430048993 0.431425149699478 0.814589373874338 GO:0003697 single-stranded DNA binding 25/3674 121/18639 0.206611570247934 1.04818537230573 0.43205272785994 0.814589373874338 GO:0016779 nucleotidyltransferase activity 28/3674 136/18639 0.205882352941176 1.04448589452112 0.43218154560248 0.814589373874338 GO:0005092 GDP-dissociation inhibitor activity 4/3674 17/18639 0.235294117647059 1.19369816516699 0.4390356411331 0.822885237989693 GO:0016805 dipeptidase activity 4/3674 17/18639 0.235294117647059 1.19369816516699 0.4390356411331 0.822885237989693 GO:0031489 myosin V binding 4/3674 17/18639 0.235294117647059 1.19369816516699 0.4390356411331 0.822885237989693 GO:0032183 SUMO binding 4/3674 17/18639 0.235294117647059 1.19369816516699 0.4390356411331 0.822885237989693 GO:0008970 phospholipase A1 activity 5/3674 22/18639 0.227272727272727 1.1530039095363 0.443420647756694 0.826486818457615 GO:0031683 G-protein beta/gamma-subunit complex binding 5/3674 22/18639 0.227272727272727 1.1530039095363 0.443420647756694 0.826486818457615 GO:0034062 5'-3' RNA polymerase activity 5/3674 22/18639 0.227272727272727 1.1530039095363 0.443420647756694 0.826486818457615 GO:0097747 RNA polymerase activity 5/3674 22/18639 0.227272727272727 1.1530039095363 0.443420647756694 0.826486818457615 GO:0008266 poly(U) RNA binding 6/3674 27/18639 0.222222222222222 1.12738160043549 0.446206272481471 0.829375093725948 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 6/3674 27/18639 0.222222222222222 1.12738160043549 0.446206272481471 0.829375093725948 GO:0008378 galactosyltransferase activity 7/3674 32/18639 0.21875 1.10976626292869 0.448074456591327 0.829546938007242 GO:0022884 macromolecule transmembrane transporter activity 7/3674 32/18639 0.21875 1.10976626292869 0.448074456591327 0.829546938007242 GO:0042805 actinin binding 8/3674 37/18639 0.216216216216216 1.09691182745075 0.449365191669024 0.829546938007242 GO:0070001 aspartic-type peptidase activity 8/3674 37/18639 0.216216216216216 1.09691182745075 0.449365191669024 0.829546938007242 GO:0140359 ABC-type transporter activity 10/3674 47/18639 0.212765957446809 1.07940791531058 0.450898603235375 0.829546938007242 GO:0004601 peroxidase activity 12/3674 57/18639 0.210526315789474 1.06804572672836 0.451611706658085 0.829546938007242 GO:0070279 vitamin B6 binding 12/3674 57/18639 0.210526315789474 1.06804572672836 0.451611706658085 0.829546938007242 GO:0015179 L-amino acid transmembrane transporter activity 13/3674 62/18639 0.209677419354839 1.06373909073349 0.451778796127428 0.829546938007242 GO:0042379 chemokine receptor binding 15/3674 72/18639 0.208333333333333 1.05692025040827 0.451862005725256 0.829546938007242 GO:0005496 steroid binding 22/3674 108/18639 0.203703703703704 1.03343313373253 0.469869588492624 0.861131513299763 GO:0004857 enzyme inhibitor activity 83/3674 416/18639 0.199519230769231 1.01220439366023 0.470349775893238 0.861131513299763 GO:0022804 active transmembrane transporter activity 91/3674 457/18639 0.199124726477024 1.01020298769876 0.475560126928718 0.865749784920162 GO:0030145 manganese ion binding 14/3674 68/18639 0.205882352941176 1.04448589452112 0.475982812985999 0.865749784920162 GO:0038187 pattern recognition receptor activity 10/3674 48/18639 0.208333333333333 1.05692025040827 0.479670490294551 0.865749784920162 GO:0008200 ion channel inhibitor activity 9/3674 43/18639 0.209302325581395 1.06183615854971 0.480690208406229 0.865749784920162 GO:0070851 growth factor receptor binding 28/3674 139/18639 0.201438848920863 1.02194303348829 0.482841840733322 0.865749784920162 GO:0140098 catalytic activity, acting on RNA 77/3674 387/18639 0.198966408268734 1.00939980504108 0.483837243458576 0.865749784920162 GO:0016866 intramolecular transferase activity 6/3674 28/18639 0.214285714285714 1.08711797184851 0.484055372785044 0.865749784920162 GO:0050698 proteoglycan sulfotransferase activity 6/3674 28/18639 0.214285714285714 1.08711797184851 0.484055372785044 0.865749784920162 GO:0000295 adenine nucleotide transmembrane transporter activity 5/3674 23/18639 0.217391304347826 1.10287330477385 0.485284961613315 0.865749784920162 GO:0008308 voltage-gated monoatomic anion channel activity 4/3674 18/18639 0.222222222222222 1.12738160043549 0.486541544809018 0.865749784920162 GO:0008525 phosphatidylcholine transporter activity 4/3674 18/18639 0.222222222222222 1.12738160043549 0.486541544809018 0.865749784920162 GO:0015373 monoatomic anion:sodium symporter activity 4/3674 18/18639 0.222222222222222 1.12738160043549 0.486541544809018 0.865749784920162 GO:0031690 adrenergic receptor binding 4/3674 18/18639 0.222222222222222 1.12738160043549 0.486541544809018 0.865749784920162 GO:1990381 ubiquitin-specific protease binding 4/3674 18/18639 0.222222222222222 1.12738160043549 0.486541544809018 0.865749784920162 GO:0004465 lipoprotein lipase activity 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0008253 5'-nucleotidase activity 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0008417 fucosyltransferase activity 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0071714 icosanoid transmembrane transporter activity 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0071837 HMG box domain binding 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0089720 caspase binding 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/3674 13/18639 0.230769230769231 1.17074243122147 0.487710012965457 0.865749784920162 GO:0015370 solute:sodium symporter activity 16/3674 79/18639 0.20253164556962 1.02748702824501 0.496705098521296 0.88055249962428 GO:0003684 damaged DNA binding 15/3674 74/18639 0.202702702702703 1.02835483823508 0.498266306324622 0.881327068993341 GO:0008194 UDP-glycosyltransferase activity 29/3674 145/18639 0.2 1.01464344039194 0.498455473447054 0.881327068993341 GO:0051287 NAD binding 11/3674 54/18639 0.203703703703704 1.03343313373253 0.505774739750695 0.893091711507148 GO:0016248 channel inhibitor activity 9/3674 44/18639 0.204545454545455 1.03770351858267 0.510699535417306 0.900602860092016 GO:0016776 phosphotransferase activity, phosphate group as acceptor 8/3674 39/18639 0.205128205128205 1.04065993886353 0.513639572171367 0.904598826580019 GO:0008376 acetylgalactosaminyltransferase activity 7/3674 34/18639 0.205882352941176 1.04448589452112 0.517033365474105 0.907004936557188 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 7/3674 34/18639 0.205882352941176 1.04448589452112 0.517033365474105 0.907004936557188 GO:0016831 carboxy-lyase activity 7/3674 34/18639 0.205882352941176 1.04448589452112 0.517033365474105 0.907004936557188 GO:0044325 transmembrane transporter binding 27/3674 136/18639 0.198529411764706 1.00718282685965 0.517905220500868 0.907348310590293 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 6/3674 29/18639 0.206896551724138 1.04963114523304 0.521051293765428 0.908117969134032 GO:0005416 amino acid:monoatomic cation symporter activity 6/3674 29/18639 0.206896551724138 1.04963114523304 0.521051293765428 0.908117969134032 GO:0097472 cyclin-dependent protein kinase activity 6/3674 29/18639 0.206896551724138 1.04963114523304 0.521051293765428 0.908117969134032 GO:0099604 ligand-gated calcium channel activity 6/3674 29/18639 0.206896551724138 1.04963114523304 0.521051293765428 0.908117969134032 GO:0008201 heparin binding 34/3674 172/18639 0.197674418604651 1.0028452608525 0.523360507907126 0.910959535163895 GO:0030552 cAMP binding 5/3674 24/18639 0.208333333333333 1.05692025040827 0.525974791759266 0.913141229677794 GO:0050699 WW domain binding 5/3674 24/18639 0.208333333333333 1.05692025040827 0.525974791759266 0.913141229677794 GO:0003756 protein disulfide isomerase activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0008381 mechanosensitive monoatomic ion channel activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0008574 plus-end-directed microtubule motor activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0016918 retinal binding 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0022821 solute:potassium antiporter activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0050145 nucleoside monophosphate kinase activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0070003 threonine-type peptidase activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:1990380 K48-linked deubiquitinase activity 4/3674 19/18639 0.210526315789474 1.06804572672836 0.532313142415504 0.913509254631211 GO:0005313 L-glutamate transmembrane transporter activity 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0015386 potassium:proton antiporter activity 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0031404 chloride ion binding 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0043176 amine binding 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0044548 S100 protein binding 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0098847 sequence-specific single stranded DNA binding 3/3674 14/18639 0.214285714285714 1.08711797184851 0.541118355613833 0.920381284199955 GO:0098631 cell adhesion mediator activity 15/3674 76/18639 0.197368421052632 1.00129286880784 0.543773375699966 0.923726417961208 GO:0015036 disulfide oxidoreductase activity 8/3674 40/18639 0.2 1.01464344039194 0.544836901265205 0.92394809938288 GO:0043022 ribosome binding 22/3674 112/18639 0.196428571428571 0.996524807527801 0.545280845537437 0.92394809938288 GO:0003743 translation initiation factor activity 10/3674 51/18639 0.196078431372549 0.994748470972493 0.563449609651458 0.949273815536401 GO:0005010 insulin-like growth factor receptor activity 10/3674 51/18639 0.196078431372549 0.994748470972493 0.563449609651458 0.949273815536401 GO:0016830 carbon-carbon lyase activity 10/3674 51/18639 0.196078431372549 0.994748470972493 0.563449609651458 0.949273815536401 GO:0015662 P-type ion transporter activity 5/3674 25/18639 0.2 1.01464344039194 0.565178672588364 0.949273815536401 GO:0017056 structural constituent of nuclear pore 5/3674 25/18639 0.2 1.01464344039194 0.565178672588364 0.949273815536401 GO:0120020 cholesterol transfer activity 5/3674 25/18639 0.2 1.01464344039194 0.565178672588364 0.949273815536401 GO:0140358 P-type transmembrane transporter activity 5/3674 25/18639 0.2 1.01464344039194 0.565178672588364 0.949273815536401 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 9/3674 46/18639 0.195652173913043 0.992585974296466 0.568905181388461 0.954338441779143 GO:0005539 glycosaminoglycan binding 47/3674 242/18639 0.194214876033058 0.985294249967383 0.571373607943302 0.956596520736983 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 8/3674 41/18639 0.195121951219512 0.989896039406774 0.57519824134105 0.956596520736983 GO:0140828 metal cation:monoatomic cation antiporter activity 8/3674 41/18639 0.195121951219512 0.989896039406774 0.57519824134105 0.956596520736983 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/3674 20/18639 0.2 1.01464344039194 0.575953791919137 0.956596520736983 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/3674 20/18639 0.2 1.01464344039194 0.575953791919137 0.956596520736983 GO:0042288 MHC class I protein binding 4/3674 20/18639 0.2 1.01464344039194 0.575953791919137 0.956596520736983 GO:0043024 ribosomal small subunit binding 4/3674 20/18639 0.2 1.01464344039194 0.575953791919137 0.956596520736983 GO:0052745 inositol phosphate phosphatase activity 4/3674 20/18639 0.2 1.01464344039194 0.575953791919137 0.956596520736983 GO:0019842 vitamin binding 29/3674 150/18639 0.193333333333333 0.980821992378879 0.579300064496604 0.957571219706796 GO:0000774 adenyl-nucleotide exchange factor activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0008242 omega peptidase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0008252 nucleotidase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0016846 carbon-sulfur lyase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0030553 cGMP binding 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0031386 protein tag activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0033130 acetylcholine receptor binding 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0034483 heparan sulfate sulfotransferase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0045504 dynein heavy chain binding 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0050780 dopamine receptor binding 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0051371 muscle alpha-actinin binding 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0140161 monocarboxylate:sodium symporter activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0141047 molecular tag activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0141050 histone H3K deacetylase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0141051 histone H4K deacetylase activity 3/3674 15/18639 0.2 1.01464344039194 0.591146798492999 0.957571219706796 GO:0005164 tumor necrosis factor receptor binding 6/3674 31/18639 0.193548387096774 0.981913006830913 0.591524993395629 0.957571219706796 GO:0047499 calcium-independent phospholipase A2 activity 6/3674 31/18639 0.193548387096774 0.981913006830913 0.591524993395629 0.957571219706796 GO:0072349 modified amino acid transmembrane transporter activity 6/3674 31/18639 0.193548387096774 0.981913006830913 0.591524993395629 0.957571219706796 GO:0005227 calcium-activated cation channel activity 5/3674 26/18639 0.192307692307692 0.975618692684561 0.602650595858538 0.960426553287677 GO:0015216 purine nucleotide transmembrane transporter activity 5/3674 26/18639 0.192307692307692 0.975618692684561 0.602650595858538 0.960426553287677 GO:0030507 spectrin binding 5/3674 26/18639 0.192307692307692 0.975618692684561 0.602650595858538 0.960426553287677 GO:0051139 metal cation:proton antiporter activity 5/3674 26/18639 0.192307692307692 0.975618692684561 0.602650595858538 0.960426553287677 GO:0004520 DNA endonuclease activity 8/3674 42/18639 0.19047619047619 0.966327086087565 0.604593522191163 0.960426553287677 GO:0031492 nucleosomal DNA binding 8/3674 42/18639 0.19047619047619 0.966327086087565 0.604593522191163 0.960426553287677 GO:0004175 endopeptidase activity 78/3674 405/18639 0.192592592592593 0.97706405371076 0.611457897811089 0.960426553287677 GO:0015108 chloride transmembrane transporter activity 23/3674 121/18639 0.190082644628099 0.964330542521268 0.613537310292523 0.960426553287677 GO:0019213 deacetylase activity 7/3674 37/18639 0.189189189189189 0.959797849019406 0.613687858984899 0.960426553287677 GO:0030551 cyclic nucleotide binding 7/3674 37/18639 0.189189189189189 0.959797849019406 0.613687858984899 0.960426553287677 GO:0004955 prostaglandin receptor activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0005337 nucleoside transmembrane transporter activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0008190 eukaryotic initiation factor 4E binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0015187 glycine transmembrane transporter activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0015203 polyamine transmembrane transporter activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0015279 store-operated calcium channel activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0019911 structural constituent of myelin sheath 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0031419 cobalamin binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0031434 mitogen-activated protein kinase kinase binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0043121 neurotrophin binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0050308 sugar-phosphatase activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0051880 G-quadruplex DNA binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0140940 histone H2A methyltransferase activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0141109 transporter activator activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:1905394 retromer complex binding 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:1990259 histone H2AQ104 methyltransferase activity 2/3674 10/18639 0.2 1.01464344039194 0.615474542345307 0.960426553287677 GO:0008373 sialyltransferase activity 4/3674 21/18639 0.19047619047619 0.966327086087565 0.617175698032109 0.961962586247492 GO:0016879 ligase activity, forming carbon-nitrogen bonds 9/3674 48/18639 0.1875 0.951228225367447 0.623896481062045 0.971309834785689 GO:0000062 fatty-acyl-CoA binding 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0005149 interleukin-1 receptor binding 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0008296 3'-5'-DNA exonuclease activity 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0022841 potassium ion leak channel activity 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0043023 ribosomal large subunit binding 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0097027 ubiquitin-protein transferase activator activity 3/3674 16/18639 0.1875 0.951228225367447 0.637493652823154 0.982193369578169 GO:0004364 glutathione transferase activity 5/3674 27/18639 0.185185185185185 0.939484667029577 0.638206123898781 0.982193369578169 GO:0035255 ionotropic glutamate receptor binding 5/3674 27/18639 0.185185185185185 0.939484667029577 0.638206123898781 0.982193369578169 GO:0016853 isomerase activity 34/3674 180/18639 0.188888888888889 0.958274360370169 0.639264191663496 0.982694782602991 GO:0005501 retinoid binding 7/3674 38/18639 0.184210526315789 0.934540010887316 0.643478469870544 0.986344016023522 GO:0019840 isoprenoid binding 7/3674 38/18639 0.184210526315789 0.934540010887316 0.643478469870544 0.986344016023522 GO:0008509 monoatomic anion transmembrane transporter activity 28/3674 149/18639 0.187919463087248 0.953356252717262 0.643843038775414 0.986344016023522 GO:0141108 transporter regulator activity 32/3674 170/18639 0.188235294117647 0.954958532133594 0.645247940725436 0.987343290643979 GO:0008238 exopeptidase activity 19/3674 102/18639 0.186274509803922 0.945011047423869 0.647716987646449 0.987343290643979 GO:0015171 amino acid transmembrane transporter activity 19/3674 102/18639 0.186274509803922 0.945011047423869 0.647716987646449 0.987343290643979 GO:0015103 inorganic anion transmembrane transporter activity 31/3674 165/18639 0.187878787878788 0.953149898550007 0.64840739204271 0.987343290643979 GO:0160215 deacylase activity 12/3674 65/18639 0.184615384615385 0.936593944977179 0.649047463938427 0.987343290643979 GO:0033691 sialic acid binding 4/3674 22/18639 0.181818181818182 0.922403127629039 0.655787931426646 0.987343290643979 GO:0061133 endopeptidase activator activity 4/3674 22/18639 0.181818181818182 0.922403127629039 0.655787931426646 0.987343290643979 GO:0140035 ubiquitin-like protein reader activity 4/3674 22/18639 0.181818181818182 0.922403127629039 0.655787931426646 0.987343290643979 GO:0051536 iron-sulfur cluster binding 14/3674 76/18639 0.184210526315789 0.934540010887316 0.656617617765185 0.987343290643979 GO:0004714 transmembrane receptor protein tyrosine kinase activity 11/3674 60/18639 0.183333333333333 0.930089820359281 0.656712788513504 0.987343290643979 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/3674 44/18639 0.181818181818182 0.922403127629039 0.660073111674478 0.987343290643979 GO:0001664 G protein-coupled receptor binding 56/3674 297/18639 0.188552188552189 0.956566206430115 0.66847607333913 0.987343290643979 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0000099 sulfur amino acid transmembrane transporter activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0001851 complement component C3b binding 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0004954 prostanoid receptor activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0008046 axon guidance receptor activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0008172 S-methyltransferase activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0008199 ferric iron binding 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0010854 adenylate cyclase regulator activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0015173 aromatic amino acid transmembrane transporter activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0016594 glycine binding 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0019206 nucleoside kinase activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0032404 mismatch repair complex binding 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0035252 UDP-xylosyltransferase activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0042285 xylosyltransferase activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0047676 arachidonate-CoA ligase activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0050998 nitric-oxide synthase binding 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0099528 G protein-coupled neurotransmitter receptor activity 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0140031 phosphorylation-dependent protein binding 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/3674 11/18639 0.181818181818182 0.922403127629039 0.669355920409216 0.987343290643979 GO:0017171 serine hydrolase activity 37/3674 198/18639 0.186868686868687 0.948025436729846 0.669932169535105 0.987343290643979 GO:0046625 sphingolipid binding 5/3674 28/18639 0.178571428571429 0.905931643207092 0.671717156749593 0.987343290643979 GO:0051119 sugar transmembrane transporter activity 5/3674 28/18639 0.178571428571429 0.905931643207092 0.671717156749593 0.987343290643979 GO:0051393 alpha-actinin binding 5/3674 28/18639 0.178571428571429 0.905931643207092 0.671717156749593 0.987343290643979 GO:0051959 dynein light intermediate chain binding 5/3674 28/18639 0.178571428571429 0.905931643207092 0.671717156749593 0.987343290643979 GO:0048020 CCR chemokine receptor binding 9/3674 50/18639 0.18 0.913179096352749 0.674948518359036 0.988718673913139 GO:0046943 carboxylic acid transmembrane transporter activity 35/3674 188/18639 0.186170212765957 0.944481925896756 0.676066788164827 0.988718673913139 GO:0051540 metal cluster binding 14/3674 77/18639 0.181818181818182 0.922403127629039 0.676749872962178 0.988718673913139 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 11/3674 61/18639 0.180327868852459 0.914842446255031 0.679229923494872 0.988718673913139 GO:0004659 prenyltransferase activity 3/3674 17/18639 0.176470588235294 0.895273623875244 0.68002036961388 0.988718673913139 GO:0009881 photoreceptor activity 3/3674 17/18639 0.176470588235294 0.895273623875244 0.68002036961388 0.988718673913139 GO:0016018 cyclosporin A binding 3/3674 17/18639 0.176470588235294 0.895273623875244 0.68002036961388 0.988718673913139 GO:0045236 CXCR chemokine receptor binding 3/3674 17/18639 0.176470588235294 0.895273623875244 0.68002036961388 0.988718673913139 GO:0048038 quinone binding 3/3674 17/18639 0.176470588235294 0.895273623875244 0.68002036961388 0.988718673913139 GO:1901567 fatty acid derivative binding 3/3674 17/18639 0.176470588235294 0.895273623875244 0.68002036961388 0.988718673913139 GO:0008236 serine-type peptidase activity 36/3674 194/18639 0.185567010309278 0.941421748817267 0.68555603595152 0.995688528405778 GO:0005342 organic acid transmembrane transporter activity 35/3674 189/18639 0.185185185185185 0.939484667029577 0.688776324431992 0.998676655973788 GO:0005254 chloride channel activity 15/3674 83/18639 0.180722891566265 0.916846482281876 0.689101776029603 0.998676655973788 GO:0017134 fibroblast growth factor binding 4/3674 23/18639 0.173913043478261 0.882298643819081 0.691683293492611 0.999702154155554 GO:0031681 G-protein beta-subunit binding 4/3674 23/18639 0.173913043478261 0.882298643819081 0.691683293492611 0.999702154155554 GO:0008173 RNA methyltransferase activity 12/3674 67/18639 0.17910447761194 0.908635916768905 0.692044188681453 0.999702154155554 GO:0015144 carbohydrate transmembrane transporter activity 7/3674 40/18639 0.175 0.88781301034295 0.698829419419186 1 GO:0005021 vascular endothelial growth factor receptor activity 9/3674 51/18639 0.176470588235294 0.895273623875244 0.698841141653517 1 GO:0003785 actin monomer binding 5/3674 29/18639 0.172413793103448 0.874692621027537 0.703105878204627 1 GO:0046982 protein heterodimerization activity 69/3674 369/18639 0.186991869918699 0.948650371098158 0.709116217632063 1 GO:0016504 peptidase activator activity 10/3674 57/18639 0.175438596491228 0.890038105606968 0.710632882119158 1 GO:0004867 serine-type endopeptidase inhibitor activity 17/3674 95/18639 0.178947368421053 0.907838867719107 0.711431886864374 1 GO:0004623 phospholipase A2 activity 6/3674 35/18639 0.171428571428571 0.869694377478809 0.713990964325817 1 GO:0004859 phospholipase inhibitor activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0005436 sodium:phosphate symporter activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0015132 prostaglandin transmembrane transporter activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0015166 polyol transmembrane transporter activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0016208 AMP binding 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0016801 hydrolase activity, acting on ether bonds 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0016803 ether hydrolase activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0016840 carbon-nitrogen lyase activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0031543 peptidyl-proline dioxygenase activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0036009 protein-glutamine N-methyltransferase activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0042301 phosphate ion binding 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0045295 gamma-catenin binding 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0140900 chloride:bicarbonate antiporter activity 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:1990459 transferrin receptor binding 2/3674 12/18639 0.166666666666667 0.845536200326619 0.716942074551164 1 GO:0003746 translation elongation factor activity 3/3674 18/18639 0.166666666666667 0.845536200326619 0.718716134574853 1 GO:0032393 MHC class I receptor activity 3/3674 18/18639 0.166666666666667 0.845536200326619 0.718716134574853 1 GO:0048029 monosaccharide binding 13/3674 74/18639 0.175675675675676 0.891240859803734 0.722966216494691 1 GO:0099106 ion channel regulator activity 29/3674 160/18639 0.18125 0.919520617855199 0.723584527965246 1 GO:0140318 protein transporter activity 7/3674 41/18639 0.170731707317073 0.866159034480927 0.724282897258802 1 GO:0005315 phosphate transmembrane transporter activity 4/3674 24/18639 0.166666666666667 0.845536200326619 0.72482499383928 1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/3674 24/18639 0.166666666666667 0.845536200326619 0.72482499383928 1 GO:0070300 phosphatidic acid binding 4/3674 24/18639 0.166666666666667 0.845536200326619 0.72482499383928 1 GO:0001965 G-protein alpha-subunit binding 5/3674 30/18639 0.166666666666667 0.845536200326619 0.732338307501844 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 5/3674 30/18639 0.166666666666667 0.845536200326619 0.732338307501844 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/3674 30/18639 0.166666666666667 0.845536200326619 0.732338307501844 1 GO:0015215 nucleotide transmembrane transporter activity 5/3674 30/18639 0.166666666666667 0.845536200326619 0.732338307501844 1 GO:0022839 monoatomic ion-gated channel activity 5/3674 30/18639 0.166666666666667 0.845536200326619 0.732338307501844 1 GO:0033612 receptor serine/threonine kinase binding 5/3674 30/18639 0.166666666666667 0.845536200326619 0.732338307501844 1 GO:0099095 ligand-gated monoatomic anion channel activity 8/3674 47/18639 0.170212765957447 0.863526332248462 0.733998626018858 1 GO:0004033 aldo-keto reductase (NADPH) activity 6/3674 36/18639 0.166666666666667 0.845536200326619 0.74026919983298 1 GO:0045505 dynein intermediate chain binding 6/3674 36/18639 0.166666666666667 0.845536200326619 0.74026919983298 1 GO:0055106 ubiquitin-protein transferase regulator activity 6/3674 36/18639 0.166666666666667 0.845536200326619 0.74026919983298 1 GO:0008146 sulfotransferase activity 9/3674 53/18639 0.169811320754717 0.861489713540329 0.743176808884464 1 GO:0016251 RNA polymerase II general transcription initiation factor activity 9/3674 53/18639 0.169811320754717 0.861489713540329 0.743176808884464 1 GO:0038064 collagen receptor activity 9/3674 53/18639 0.169811320754717 0.861489713540329 0.743176808884464 1 GO:0016782 transferase activity, transferring sulphur-containing groups 12/3674 70/18639 0.171428571428571 0.869694377478809 0.750252979622195 1 GO:0036002 pre-mRNA binding 10/3674 59/18639 0.169491525423729 0.859867322366054 0.751860589372956 1 GO:0070888 E-box binding 10/3674 59/18639 0.169491525423729 0.859867322366054 0.751860589372956 1 GO:0005253 monoatomic anion channel activity 18/3674 103/18639 0.174757281553398 0.886581646944417 0.752670743216336 1 GO:0008301 DNA binding, bending 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0022840 leak channel activity 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0022842 narrow pore channel activity 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0031420 alkali metal ion binding 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0034987 immunoglobulin receptor binding 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0042577 lipid phosphatase activity 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0140036 ubiquitin-modified protein reader activity 3/3674 19/18639 0.157894736842105 0.801034295046271 0.75366669560473 1 GO:0008514 organic anion transmembrane transporter activity 49/3674 269/18639 0.182156133828996 0.92411763158374 0.755052912664348 1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/3674 25/18639 0.16 0.811714752313555 0.755233816934693 1 GO:0047617 fatty acyl-CoA hydrolase activity 4/3674 25/18639 0.16 0.811714752313555 0.755233816934693 1 GO:0016247 channel regulator activity 30/3674 168/18639 0.178571428571429 0.905931643207092 0.756264406535566 1 GO:0005172 vascular endothelial growth factor receptor binding 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0009982 pseudouridine synthase activity 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0032396 inhibitory MHC class I receptor activity 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0051011 microtubule minus-end binding 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0061459 L-arginine transmembrane transporter activity 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0140333 glycerophospholipid flippase activity 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0140666 annealing activity 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:1901338 catecholamine binding 2/3674 13/18639 0.153846153846154 0.780494954147649 0.75862063120311 1 GO:0017069 snRNA binding 9/3674 54/18639 0.166666666666667 0.845536200326619 0.763586328782741 1 GO:0003774 cytoskeletal motor activity 27/3674 153/18639 0.176470588235294 0.895273623875244 0.769559003360984 1 GO:0004222 metalloendopeptidase activity 19/3674 110/18639 0.172727272727273 0.876282971247587 0.774833634533902 1 GO:0005004 GPI-linked ephrin receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0005008 hepatocyte growth factor receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0005009 insulin receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0005011 macrophage colony-stimulating factor receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0005020 stem cell factor receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0008288 boss receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0036332 placental growth factor receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0038062 protein tyrosine kinase collagen receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0060175 brain-derived neurotrophic factor receptor activity 8/3674 49/18639 0.163265306122449 0.828280359503627 0.776715451941613 1 GO:0098632 cell-cell adhesion mediator activity 9/3674 55/18639 0.163636363636364 0.830162814866136 0.782820566295045 1 GO:0008198 ferrous iron binding 4/3674 26/18639 0.153846153846154 0.780494954147649 0.782976220766721 1 GO:0015145 monosaccharide transmembrane transporter activity 4/3674 26/18639 0.153846153846154 0.780494954147649 0.782976220766721 1 GO:0016289 acyl-CoA hydrolase activity 4/3674 26/18639 0.153846153846154 0.780494954147649 0.782976220766721 1 GO:0031369 translation initiation factor binding 5/3674 32/18639 0.15625 0.792690187806206 0.784378684975737 1 GO:0047498 calcium-dependent phospholipase A2 activity 5/3674 32/18639 0.15625 0.792690187806206 0.784378684975737 1 GO:0001972 retinoic acid binding 3/3674 20/18639 0.15 0.760982580293957 0.785027796255129 1 GO:0030742 GTP-dependent protein binding 3/3674 20/18639 0.15 0.760982580293957 0.785027796255129 1 GO:0061608 nuclear import signal receptor activity 3/3674 20/18639 0.15 0.760982580293957 0.785027796255129 1 GO:0019205 nucleobase-containing compound kinase activity 7/3674 44/18639 0.159090909090909 0.80710273667541 0.79155981897293 1 GO:0005161 platelet-derived growth factor receptor binding 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0005347 ATP transmembrane transporter activity 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0008195 phosphatidate phosphatase activity 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0008559 ABC-type xenobiotic transporter activity 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0030983 mismatched DNA binding 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0032036 myosin heavy chain binding 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0071933 Arp2/3 complex binding 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:1901474 azole transmembrane transporter activity 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:1901612 cardiolipin binding 2/3674 14/18639 0.142857142857143 0.724745314565674 0.79487101046799 1 GO:0005006 epidermal growth factor receptor activity 8/3674 50/18639 0.16 0.811714752313555 0.796099629766866 1 GO:0005007 fibroblast growth factor receptor activity 8/3674 50/18639 0.16 0.811714752313555 0.796099629766866 1 GO:0005017 platelet-derived growth factor receptor activity 8/3674 50/18639 0.16 0.811714752313555 0.796099629766866 1 GO:0005019 platelet-derived growth factor beta-receptor activity 8/3674 50/18639 0.16 0.811714752313555 0.796099629766866 1 GO:0004521 RNA endonuclease activity 12/3674 73/18639 0.164383561643836 0.833953512650912 0.800570259993098 1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 5/3674 33/18639 0.151515151515152 0.7686692730242 0.807280409177931 1 GO:0019239 deaminase activity 5/3674 33/18639 0.151515151515152 0.7686692730242 0.807280409177931 1 GO:0008320 protein transmembrane transporter activity 4/3674 27/18639 0.148148148148148 0.751587733623662 0.808153628917667 1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/3674 39/18639 0.153846153846154 0.780494954147649 0.808534394661325 1 GO:0140223 general transcription initiation factor activity 11/3674 68/18639 0.161764705882353 0.820667488552307 0.810706364742739 1 GO:0001846 opsonin binding 3/3674 21/18639 0.142857142857143 0.724745314565674 0.813003145958966 1 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/3674 21/18639 0.142857142857143 0.724745314565674 0.813003145958966 1 GO:0015125 bile acid transmembrane transporter activity 3/3674 21/18639 0.142857142857143 0.724745314565674 0.813003145958966 1 GO:0051428 peptide hormone receptor binding 3/3674 21/18639 0.142857142857143 0.724745314565674 0.813003145958966 1 GO:0061891 calcium ion sensor activity 3/3674 21/18639 0.142857142857143 0.724745314565674 0.813003145958966 1 GO:0005030 neurotrophin receptor activity 8/3674 51/18639 0.156862745098039 0.795798776777995 0.814194232206559 1 GO:0004467 long-chain fatty acid-CoA ligase activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0004953 icosanoid receptor activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0008020 G protein-coupled photoreceptor activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0010181 FMN binding 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0017081 chloride channel regulator activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0048531 beta-1,3-galactosyltransferase activity 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0050700 CARD domain binding 2/3674 15/18639 0.133333333333333 0.676428960261296 0.826213196925681 1 GO:0140662 ATP-dependent protein folding chaperone 6/3674 40/18639 0.15 0.760982580293957 0.827894096174644 1 GO:0008175 tRNA methyltransferase activity 5/3674 34/18639 0.147058823529412 0.74606135322937 0.828201989527372 1 GO:0015035 protein-disulfide reductase activity 5/3674 34/18639 0.147058823529412 0.74606135322937 0.828201989527372 1 GO:0004180 carboxypeptidase activity 7/3674 46/18639 0.152173913043478 0.772011313341696 0.829016018822394 1 GO:0044183 protein folding chaperone 12/3674 75/18639 0.16 0.811714752313555 0.829753024699412 1 GO:0051537 2 iron, 2 sulfur cluster binding 4/3674 28/18639 0.142857142857143 0.724745314565674 0.83089304094568 1 GO:0004407 histone deacetylase activity 3/3674 22/18639 0.136363636363636 0.69180234572178 0.837826600885122 1 GO:0008649 rRNA methyltransferase activity 3/3674 22/18639 0.136363636363636 0.69180234572178 0.837826600885122 1 GO:0016881 acid-amino acid ligase activity 3/3674 22/18639 0.136363636363636 0.69180234572178 0.837826600885122 1 GO:0033558 protein lysine deacetylase activity 3/3674 22/18639 0.136363636363636 0.69180234572178 0.837826600885122 1 GO:0140784 metal ion sensor activity 3/3674 22/18639 0.136363636363636 0.69180234572178 0.837826600885122 1 GO:0004519 endonuclease activity 21/3674 127/18639 0.165354330708661 0.838878434969717 0.845209625730025 1 GO:0001530 lipopolysaccharide binding 6/3674 41/18639 0.146341463414634 0.742422029555081 0.845656015988789 1 GO:0042287 MHC protein binding 6/3674 41/18639 0.146341463414634 0.742422029555081 0.845656015988789 1 GO:0005003 ephrin receptor activity 8/3674 53/18639 0.150943396226415 0.765768634258071 0.846649623076875 1 GO:0005005 transmembrane-ephrin receptor activity 8/3674 53/18639 0.150943396226415 0.765768634258071 0.846649623076875 1 GO:0016860 intramolecular oxidoreductase activity 8/3674 53/18639 0.150943396226415 0.765768634258071 0.846649623076875 1 GO:0017046 peptide hormone binding 8/3674 53/18639 0.150943396226415 0.765768634258071 0.846649623076875 1 GO:0015399 primary active transmembrane transporter activity 28/3674 166/18639 0.168674698795181 0.855723383463085 0.847248447724042 1 GO:0003688 DNA replication origin binding 2/3674 16/18639 0.125 0.634152150244965 0.85317313179747 1 GO:0008142 oxysterol binding 2/3674 16/18639 0.125 0.634152150244965 0.85317313179747 1 GO:0015385 sodium:proton antiporter activity 2/3674 16/18639 0.125 0.634152150244965 0.85317313179747 1 GO:0019841 retinol binding 2/3674 16/18639 0.125 0.634152150244965 0.85317313179747 1 GO:0055102 lipase inhibitor activity 2/3674 16/18639 0.125 0.634152150244965 0.85317313179747 1 GO:0005212 structural constituent of eye lens 3/3674 23/18639 0.130434782608696 0.661723982864311 0.859748096993998 1 GO:0140102 catalytic activity, acting on a rRNA 3/3674 23/18639 0.130434782608696 0.661723982864311 0.859748096993998 1 GO:0008307 structural constituent of muscle 6/3674 42/18639 0.142857142857143 0.724745314565674 0.861895223274865 1 GO:0042056 chemoattractant activity 6/3674 42/18639 0.142857142857143 0.724745314565674 0.861895223274865 1 GO:0031210 phosphatidylcholine binding 4/3674 30/18639 0.133333333333333 0.676428960261296 0.869646783827695 1 GO:0048019 receptor antagonist activity 4/3674 30/18639 0.133333333333333 0.676428960261296 0.869646783827695 1 GO:0030414 peptidase inhibitor activity 28/3674 169/18639 0.165680473372781 0.840533027543622 0.871892450687561 1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 10/3674 67/18639 0.149253731343284 0.75719659730742 0.875470112133475 1 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0004549 tRNA-specific ribonuclease activity 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0004550 nucleoside diphosphate kinase activity 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0032977 membrane insertase activity 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0051787 misfolded protein binding 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0070402 NADPH binding 2/3674 17/18639 0.117647058823529 0.596849082583496 0.876260166755282 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/3674 43/18639 0.13953488372093 0.707890772366472 0.876693127723419 1 GO:0015149 hexose transmembrane transporter activity 3/3674 24/18639 0.125 0.634152150244965 0.879022826016101 1 GO:0055056 D-glucose transmembrane transporter activity 3/3674 24/18639 0.125 0.634152150244965 0.879022826016101 1 GO:0005262 calcium channel activity 21/3674 131/18639 0.16030534351145 0.813263826268351 0.881583795823024 1 GO:0061134 peptidase regulator activity 38/3674 226/18639 0.168141592920354 0.853018821568448 0.883646976908467 1 GO:0005452 solute:inorganic anion antiporter activity 4/3674 31/18639 0.129032258064516 0.654608671220609 0.885977004989753 1 GO:0000182 rDNA binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0001094 TFIID-class transcription factor complex binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0003796 lysozyme activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0005522 profilin binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0005528 FK506 binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0016427 tRNA (cytidine) methyltransferase activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0016783 sulfurtransferase activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0032052 bile acid binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0033204 ribonuclease P RNA binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0051378 serotonin binding 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0140135 mechanosensitive monoatomic cation channel activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:1990757 ubiquitin ligase activator activity 1/3674 10/18639 0.1 0.507321720195972 0.888754202555641 1 GO:0030547 signaling receptor inhibitor activity 6/3674 44/18639 0.136363636363636 0.69180234572178 0.890135229105075 1 GO:0004866 endopeptidase inhibitor activity 26/3674 161/18639 0.161490683229814 0.819277312117718 0.894920679655047 1 GO:0001848 complement binding 3/3674 25/18639 0.12 0.608786064235166 0.895903145436293 1 GO:0015271 outward rectifier potassium channel activity 3/3674 25/18639 0.12 0.608786064235166 0.895903145436293 1 GO:0000400 four-way junction DNA binding 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0017128 phospholipid scramblase activity 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0098641 cadherin binding involved in cell-cell adhesion 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:1901611 phosphatidylglycerol binding 2/3674 18/18639 0.111111111111111 0.563690800217746 0.895953170777836 1 GO:0061135 endopeptidase regulator activity 30/3674 184/18639 0.16304347826087 0.827154978580389 0.898525539457946 1 GO:0015106 bicarbonate transmembrane transporter activity 4/3674 32/18639 0.125 0.634152150244965 0.900491050706041 1 GO:0042910 xenobiotic transmembrane transporter activity 4/3674 32/18639 0.125 0.634152150244965 0.900491050706041 1 GO:0140142 nucleocytoplasmic carrier activity 4/3674 32/18639 0.125 0.634152150244965 0.900491050706041 1 GO:0042562 hormone binding 14/3674 94/18639 0.148936170212766 0.755585540717405 0.908185089655662 1 GO:0120014 phospholipid transfer activity 3/3674 26/18639 0.115384615384615 0.585371215610737 0.910632744306237 1 GO:0003953 NAD+ nucleosidase activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0004016 adenylate cyclase activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0005536 D-glucose binding 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0008503 benzodiazepine receptor activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0008526 phosphatidylinositol transfer activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0015217 ADP transmembrane transporter activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0031731 CCR6 chemokine receptor binding 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0048407 platelet-derived growth factor binding 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0070697 activin receptor binding 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:1990948 ubiquitin ligase inhibitor activity 1/3674 11/18639 0.0909090909090909 0.46120156381452 0.910694030770284 1 GO:0046624 sphingolipid transporter activity 2/3674 19/18639 0.105263157894737 0.534022863364181 0.912692756092319 1 GO:0022853 active monoatomic ion transmembrane transporter activity 18/3674 118/18639 0.152542372881356 0.773880590129448 0.912901233410233 1 GO:0015085 calcium ion transmembrane transporter activity 23/3674 147/18639 0.156462585034014 0.793768677857643 0.914307926622033 1 GO:0004252 serine-type endopeptidase activity 28/3674 176/18639 0.159090909090909 0.80710273667541 0.917478196145767 1 GO:0004177 aminopeptidase activity 5/3674 40/18639 0.125 0.634152150244965 0.917933329378043 1 GO:0050997 quaternary ammonium group binding 5/3674 40/18639 0.125 0.634152150244965 0.917933329378043 1 GO:0005246 calcium channel regulator activity 7/3674 53/18639 0.132075471698113 0.670047554975812 0.919867364756521 1 GO:0015252 proton channel activity 3/3674 27/18639 0.111111111111111 0.563690800217746 0.923442633729808 1 GO:0016405 CoA-ligase activity 3/3674 27/18639 0.111111111111111 0.563690800217746 0.923442633729808 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/3674 27/18639 0.111111111111111 0.563690800217746 0.923442633729808 1 GO:0015020 glucuronosyltransferase activity 4/3674 34/18639 0.117647058823529 0.596849082583496 0.924700451102073 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/3674 34/18639 0.117647058823529 0.596849082583496 0.924700451102073 1 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/3674 34/18639 0.117647058823529 0.596849082583496 0.924700451102073 1 GO:0000339 RNA cap binding 2/3674 20/18639 0.1 0.507321720195972 0.926877751629785 1 GO:0001614 purinergic nucleotide receptor activity 2/3674 20/18639 0.1 0.507321720195972 0.926877751629785 1 GO:0010851 cyclase regulator activity 2/3674 20/18639 0.1 0.507321720195972 0.926877751629785 1 GO:0016502 nucleotide receptor activity 2/3674 20/18639 0.1 0.507321720195972 0.926877751629785 1 GO:0016505 peptidase activator activity involved in apoptotic process 2/3674 20/18639 0.1 0.507321720195972 0.926877751629785 1 GO:0000340 RNA 7-methylguanosine cap binding 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0003720 telomerase activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0003995 acyl-CoA dehydrogenase activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0004000 adenosine deaminase activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0004032 aldose reductase (NADPH) activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0004126 cytidine deaminase activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0004526 ribonuclease P activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0005049 nuclear export signal receptor activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0005527 macrolide binding 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0015269 calcium-activated potassium channel activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0015368 calcium:monoatomic cation antiporter activity 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0017166 vinculin binding 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/3674 12/18639 0.0833333333333333 0.42276810016331 0.928307844972022 1 GO:0016500 protein-hormone receptor activity 9/3674 67/18639 0.134328358208955 0.681476937576678 0.932053464278214 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 18/3674 122/18639 0.147540983606557 0.748507456026843 0.936835242745678 1 GO:0005248 voltage-gated sodium channel activity 2/3674 21/18639 0.0952380952380952 0.483163543043783 0.938864552226713 1 GO:0019200 carbohydrate kinase activity 2/3674 21/18639 0.0952380952380952 0.483163543043783 0.938864552226713 1 GO:0036122 BMP binding 2/3674 21/18639 0.0952380952380952 0.483163543043783 0.938864552226713 1 GO:0070182 DNA polymerase binding 2/3674 21/18639 0.0952380952380952 0.483163543043783 0.938864552226713 1 GO:0015081 sodium ion transmembrane transporter activity 25/3674 164/18639 0.152439024390244 0.773356280786542 0.9423317152599 1 GO:0002161 aminoacyl-tRNA editing activity 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0003964 RNA-directed DNA polymerase activity 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0019104 DNA N-glycosylase activity 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0030955 potassium ion binding 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0031432 titin binding 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0070700 BMP receptor binding 1/3674 13/18639 0.0769230769230769 0.390247477073824 0.942448446119431 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/3674 36/18639 0.111111111111111 0.563690800217746 0.943471421564228 1 GO:0005245 voltage-gated calcium channel activity 5/3674 43/18639 0.116279069767442 0.58990897697206 0.944823222379532 1 GO:0004497 monooxygenase activity 15/3674 106/18639 0.141509433962264 0.717908094616941 0.946176574124798 1 GO:0005243 gap junction channel activity 2/3674 22/18639 0.0909090909090909 0.46120156381452 0.948968347360872 1 GO:0008237 metallopeptidase activity 28/3674 184/18639 0.152173913043478 0.772011313341696 0.952422824240869 1 GO:0005344 oxygen carrier activity 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:0008191 metalloendopeptidase inhibitor activity 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:0008331 high voltage-gated calcium channel activity 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:0019992 diacylglycerol binding 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:0061783 peptidoglycan muralytic activity 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:1990825 sequence-specific mRNA binding 1/3674 14/18639 0.0714285714285714 0.362372657282837 0.953800556554157 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 19/3674 132/18639 0.143939393939394 0.73023580937299 0.955074988998107 1 GO:0140299 molecular sensor activity 9/3674 71/18639 0.126760563380282 0.64308387067095 0.956190617109495 1 GO:0016917 GABA receptor activity 2/3674 23/18639 0.0869565217391304 0.441149321909541 0.957465514062479 1 GO:0099186 structural constituent of postsynapse 2/3674 23/18639 0.0869565217391304 0.441149321909541 0.957465514062479 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 6/3674 52/18639 0.115384615384615 0.585371215610737 0.959199623438598 1 GO:0016878 acid-thiol ligase activity 3/3674 31/18639 0.0967741935483871 0.490956503415456 0.959547520568256 1 GO:0009055 electron transfer activity 16/3674 116/18639 0.137931034482759 0.69975409682203 0.962518478594643 1 GO:0004089 carbonate dehydratase activity 1/3674 15/18639 0.0666666666666667 0.338214480130648 0.962913939384763 1 GO:0015250 water channel activity 1/3674 15/18639 0.0666666666666667 0.338214480130648 0.962913939384763 1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/3674 15/18639 0.0666666666666667 0.338214480130648 0.962913939384763 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/3674 15/18639 0.0666666666666667 0.338214480130648 0.962913939384763 1 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/3674 15/18639 0.0666666666666667 0.338214480130648 0.962913939384763 1 GO:0008235 metalloexopeptidase activity 8/3674 66/18639 0.121212121212121 0.61493541841936 0.962960273414996 1 GO:0000217 DNA secondary structure binding 4/3674 39/18639 0.102564102564103 0.520329969431766 0.963719628823777 1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/3674 24/18639 0.0833333333333333 0.42276810016331 0.964596667521241 1 GO:0140612 DNA damage sensor activity 2/3674 24/18639 0.0833333333333333 0.42276810016331 0.964596667521241 1 GO:0046873 metal ion transmembrane transporter activity 74/3674 450/18639 0.164444444444444 0.834262384322265 0.968063023886932 1 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/3674 16/18639 0.0625 0.317076075122482 0.970229993223915 1 GO:0016722 oxidoreductase activity, acting on metal ions 1/3674 16/18639 0.0625 0.317076075122482 0.970229993223915 1 GO:0017070 U6 snRNA binding 1/3674 16/18639 0.0625 0.317076075122482 0.970229993223915 1 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/3674 16/18639 0.0625 0.317076075122482 0.970229993223915 1 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/3674 16/18639 0.0625 0.317076075122482 0.970229993223915 1 GO:0005251 delayed rectifier potassium channel activity 2/3674 25/18639 0.08 0.405857376156777 0.970570017267758 1 GO:0005537 D-mannose binding 2/3674 25/18639 0.08 0.405857376156777 0.970570017267758 1 GO:0015645 fatty acid ligase activity 2/3674 25/18639 0.08 0.405857376156777 0.970570017267758 1 GO:0120515 fatty acid-CoA ligase activity 2/3674 25/18639 0.08 0.405857376156777 0.970570017267758 1 GO:0042923 neuropeptide binding 3/3674 33/18639 0.0909090909090909 0.46120156381452 0.970887722517721 1 GO:0003777 microtubule motor activity 8/3674 68/18639 0.117647058823529 0.596849082583496 0.970906962818743 1 GO:0015078 proton transmembrane transporter activity 27/3674 185/18639 0.145945945945946 0.740415483529256 0.971518142062983 1 GO:0016651 oxidoreductase activity, acting on NAD(P)H 11/3674 88/18639 0.125 0.634152150244965 0.97261728458535 1 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/3674 41/18639 0.0975609756097561 0.494948019703387 0.973221606272351 1 GO:0070006 metalloaminopeptidase activity 2/3674 26/18639 0.0769230769230769 0.390247477073824 0.975564790014551 1 GO:0140101 catalytic activity, acting on a tRNA 19/3674 139/18639 0.136690647482014 0.693461344152767 0.975722746399279 1 GO:0005125 cytokine activity 35/3674 234/18639 0.14957264957265 0.758814538754658 0.975764815617725 1 GO:0008569 minus-end-directed microtubule motor activity 1/3674 17/18639 0.0588235294117647 0.298424541291748 0.976103107378205 1 GO:0030548 acetylcholine receptor regulator activity 1/3674 17/18639 0.0588235294117647 0.298424541291748 0.976103107378205 1 GO:0045125 bioactive lipid receptor activity 1/3674 17/18639 0.0588235294117647 0.298424541291748 0.976103107378205 1 GO:0070492 oligosaccharide binding 1/3674 17/18639 0.0588235294117647 0.298424541291748 0.976103107378205 1 GO:0043015 gamma-tubulin binding 3/3674 35/18639 0.0857142857142857 0.434847188739404 0.979169496965105 1 GO:0005104 fibroblast growth factor receptor binding 2/3674 27/18639 0.0740740740740741 0.375793866811831 0.979734562517331 1 GO:0008395 steroid hydroxylase activity 2/3674 27/18639 0.0740740740740741 0.375793866811831 0.979734562517331 1 GO:0004970 glutamate-gated receptor activity 1/3674 18/18639 0.0555555555555556 0.281845400108873 0.980817809531168 1 GO:0005372 water transmembrane transporter activity 1/3674 18/18639 0.0555555555555556 0.281845400108873 0.980817809531168 1 GO:0015280 ligand-gated sodium channel activity 1/3674 18/18639 0.0555555555555556 0.281845400108873 0.980817809531168 1 GO:0022851 GABA-gated chloride ion channel activity 1/3674 18/18639 0.0555555555555556 0.281845400108873 0.980817809531168 1 GO:0070628 proteasome binding 1/3674 18/18639 0.0555555555555556 0.281845400108873 0.980817809531168 1 GO:0099602 neurotransmitter receptor regulator activity 1/3674 18/18639 0.0555555555555556 0.281845400108873 0.980817809531168 1 GO:0019843 rRNA binding 7/3674 65/18639 0.107692307692308 0.546346467903354 0.981934818409995 1 GO:0005242 inward rectifier potassium channel activity 2/3674 28/18639 0.0714285714285714 0.362372657282837 0.98321040695221 1 GO:0004890 GABA-A receptor activity 1/3674 19/18639 0.0526315789473684 0.26701143168209 0.984602534722215 1 GO:0030506 ankyrin binding 1/3674 19/18639 0.0526315789473684 0.26701143168209 0.984602534722215 1 GO:0042834 peptidoglycan binding 1/3674 19/18639 0.0526315789473684 0.26701143168209 0.984602534722215 1 GO:0000049 tRNA binding 9/3674 80/18639 0.1125 0.570736935220468 0.984897450223286 1 GO:0005179 hormone activity 17/3674 132/18639 0.128787878787879 0.65336888207057 0.98543670776915 1 GO:0004181 metallocarboxypeptidase activity 2/3674 29/18639 0.0689655172413793 0.349877048411015 0.986103793221888 1 GO:0005544 calcium-dependent phospholipid binding 5/3674 53/18639 0.0943396226415094 0.478605396411294 0.986763144715946 1 GO:0046906 tetrapyrrole binding 20/3674 152/18639 0.131578947368421 0.667528579205226 0.987172726594986 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/3674 20/18639 0.05 0.253660860097986 0.987640681200764 1 GO:0015464 acetylcholine receptor activity 1/3674 20/18639 0.05 0.253660860097986 0.987640681200764 1 GO:0016836 hydro-lyase activity 6/3674 61/18639 0.0983606557377049 0.499004970684562 0.988098393598921 1 GO:0070566 adenylyltransferase activity 2/3674 30/18639 0.0666666666666667 0.338214480130648 0.988509221791008 1 GO:0098918 structural constituent of synapse 2/3674 30/18639 0.0666666666666667 0.338214480130648 0.988509221791008 1 GO:0005506 iron ion binding 20/3674 154/18639 0.12987012987013 0.658859376877885 0.989409672972799 1 GO:0020037 heme binding 18/3674 142/18639 0.126760563380282 0.64308387067095 0.989959962981294 1 GO:0009975 cyclase activity 1/3674 21/18639 0.0476190476190476 0.241581771521891 0.990079487649467 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/3674 31/18639 0.0645161290322581 0.327304335610304 0.990506580496025 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 16/3674 130/18639 0.123076923076923 0.624395963318119 0.990666511688511 1 GO:0071855 neuropeptide receptor binding 3/3674 40/18639 0.075 0.380491290146979 0.991173475155942 1 GO:0016829 lyase activity 27/3674 200/18639 0.135 0.684884322264562 0.991845348080595 1 GO:0030515 snoRNA binding 2/3674 32/18639 0.0625 0.317076075122482 0.992163231825493 1 GO:0004812 aminoacyl-tRNA ligase activity 3/3674 41/18639 0.0731707317073171 0.37121101477754 0.992590727962541 1 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/3674 41/18639 0.0731707317073171 0.37121101477754 0.992590727962541 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/3674 41/18639 0.0731707317073171 0.37121101477754 0.992590727962541 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/3674 23/18639 0.0434782608695652 0.22057466095477 0.993608599493545 1 GO:0016849 phosphorus-oxygen lyase activity 1/3674 23/18639 0.0434782608695652 0.22057466095477 0.993608599493545 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/3674 58/18639 0.0862068965517241 0.437346310513769 0.993824867563452 1 GO:0016874 ligase activity 21/3674 167/18639 0.125748502994012 0.637949468509904 0.994529069068108 1 GO:0005272 sodium channel activity 4/3674 51/18639 0.0784313725490196 0.397899388388997 0.994578534834294 1 GO:0019825 oxygen binding 2/3674 34/18639 0.0588235294117647 0.298424541291748 0.994671994508474 1 GO:0003954 NADH dehydrogenase activity 3/3674 44/18639 0.0681818181818182 0.34590117286089 0.995642625993094 1 GO:0008066 glutamate receptor activity 1/3674 26/18639 0.0384615384615385 0.195123738536912 0.996695194477996 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/3674 46/18639 0.0652173913043478 0.330861991432155 0.996954912544946 1 GO:0022829 wide pore channel activity 2/3674 37/18639 0.0540540540540541 0.274227956862687 0.997028673668602 1 GO:0030280 structural constituent of skin epidermis 2/3674 37/18639 0.0540540540540541 0.274227956862687 0.997028673668602 1 GO:0003823 antigen binding 21/3674 174/18639 0.120689655172414 0.612284834719276 0.997326019087258 1 GO:0016835 carbon-oxygen lyase activity 7/3674 79/18639 0.0886075949367089 0.44952557485719 0.997463350344111 1 GO:0008083 growth factor activity 19/3674 162/18639 0.117283950617284 0.595006955785399 0.997586076758282 1 GO:0003730 mRNA 3'-UTR binding 34/3674 262/18639 0.129770992366412 0.658356430788665 0.998510529060796 1 GO:0005200 structural constituent of cytoskeleton 11/3674 112/18639 0.0982142857142857 0.498262403763901 0.998535207835495 1 GO:0015079 potassium ion transmembrane transporter activity 18/3674 160/18639 0.1125 0.570736935220468 0.998551593153249 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5/3674 68/18639 0.0735294117647059 0.373030676614685 0.998752790834159 1 GO:0022832 voltage-gated channel activity 20/3674 175/18639 0.114285714285714 0.579796251652539 0.99881163457084 1 GO:0005184 neuropeptide hormone activity 1/3674 31/18639 0.032258064516129 0.163652167805152 0.998899438633445 1 GO:0160041 neuropeptide activity 1/3674 32/18639 0.03125 0.158538037561241 0.99911673562725 1 GO:0005244 voltage-gated monoatomic ion channel activity 19/3674 173/18639 0.109826589595376 0.55717414356783 0.999299361929296 1 GO:0022834 ligand-gated channel activity 21/3674 188/18639 0.111702127659574 0.566689155538053 0.999418797989155 1 GO:0005249 voltage-gated potassium channel activity 8/3674 98/18639 0.0816326530612245 0.414140179751814 0.999536451432725 1 GO:0099094 ligand-gated monoatomic cation channel activity 13/3674 136/18639 0.0955882352941176 0.484939879599091 0.999598143685892 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/3674 36/18639 0.0277777777777778 0.140922700054437 0.999633613820498 1 GO:0015276 ligand-gated monoatomic ion channel activity 20/3674 186/18639 0.10752688172043 0.545507226017174 0.999662657283477 1 GO:0005267 potassium channel activity 11/3674 124/18639 0.0887096774193548 0.450043461464168 0.999716410030863 1 GO:0008227 G protein-coupled amine receptor activity 1/3674 41/18639 0.024390243902439 0.123737004925847 0.999878067274894 1 GO:0022843 voltage-gated monoatomic cation channel activity 12/3674 143/18639 0.0839160839160839 0.425724520444172 0.99994514641661 1 GO:0098960 postsynaptic neurotransmitter receptor activity 3/3674 69/18639 0.0434782608695652 0.22057466095477 0.999958923367632 1 GO:0003735 structural constituent of ribosome 16/3674 175/18639 0.0914285714285714 0.463837001322031 0.999960671417517 1 GO:0008528 G protein-coupled peptide receptor activity 9/3674 122/18639 0.0737704918032787 0.374253728013422 0.999961139944774 1 GO:0008188 neuropeptide receptor activity 1/3674 48/18639 0.0208333333333333 0.105692025040827 0.999973882445834 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/3674 73/18639 0.0410958904109589 0.208488378162728 0.999981065499847 1 GO:0022824 transmitter-gated monoatomic ion channel activity 2/3674 63/18639 0.0317460317460317 0.161054514347928 0.999984139589826 1 GO:0022835 transmitter-gated channel activity 2/3674 63/18639 0.0317460317460317 0.161054514347928 0.999984139589826 1 GO:0001653 peptide receptor activity 9/3674 128/18639 0.0703125 0.356710584512793 0.999984908595256 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/3674 53/18639 0.0188679245283019 0.0957210792822588 0.999991315023413 1 GO:0030594 neurotransmitter receptor activity 5/3674 97/18639 0.0515463917525773 0.26150604133813 0.999991818987402 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/3674 56/18639 0.0178571428571429 0.0905931643207092 0.999995514599102 1 GO:0022836 gated channel activity 34/3674 318/18639 0.106918238993711 0.542419449266133 0.999995586587181 1 GO:0005261 monoatomic cation channel activity 37/3674 341/18639 0.108504398826979 0.55046638261733 0.999996801430544 1 GO:0005216 monoatomic ion channel activity 53/3674 448/18639 0.118303571428571 0.600179713624699 0.999997435161748 1 GO:0005549 odorant binding 1/3674 111/18639 0.00900900900900901 0.0457046594771146 0.999999999975927 1 GO:0045182 translation regulator activity 20/3674 356/18639 0.0561797752808989 0.285012202357287 0.999999999999996 1 GO:0004984 olfactory receptor activity 1/3674 419/18639 0.00238663484486874 0.0121079169497845 1 1 GO:0030371 translation repressor activity 13/3674 329/18639 0.0395136778115502 0.20046146998625 1 1