ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	231/5347	495/18639	0.466666666666667	1.62674396858051	7.03467361817168e-18	9.66564155136789e-15
GO:0046332	SMAD binding	55/5347	79/18639	0.69620253164557	2.4268784341391	5.32466982099476e-14	3.6580481670234e-11
GO:0019787	ubiquitin-like protein transferase activity	207/5347	479/18639	0.432150313152401	1.5064241045161	4.73674396460459e-12	2.1694287357889e-09
GO:0140297	DNA-binding transcription factor binding	209/5347	488/18639	0.42827868852459	1.49292808591918	1.03300565920538e-11	3.54837443937046e-09
GO:0016755	aminoacyltransferase activity	210/5347	496/18639	0.423387096774194	1.47587658439764	3.30007679415088e-11	9.06861103032663e-09
GO:0004842	ubiquitin-protein transferase activity	189/5347	449/18639	0.420935412026726	1.46733030573521	5.62570143065726e-10	1.28828562762051e-07
GO:0003713	transcription coactivator activity	118/5347	256/18639	0.4609375	1.60677278146624	2.08919487796019e-09	4.10079108902472e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	150/5347	349/18639	0.429799426934097	1.49822919742372	6.38431539875022e-09	1.01066200503493e-06
GO:0060589	nucleoside-triphosphatase regulator activity	199/5347	490/18639	0.406122448979592	1.41569409510578	6.62005680153887e-09	1.01066200503493e-06
GO:0003714	transcription corepressor activity	97/5347	204/18639	0.475490196078431	1.65750173269233	7.87737049736742e-09	1.08235070633828e-06
GO:0030695	GTPase regulator activity	198/5347	489/18639	0.404907975460123	1.4114605862355	9.54098882538559e-09	1.19175624055271e-06
GO:0061659	ubiquitin-like protein ligase activity	157/5347	372/18639	0.422043010752688	1.47119126190749	1.29016392887009e-08	1.47723769855625e-06
GO:0004674	protein serine/threonine kinase activity	178/5347	433/18639	0.41108545034642	1.43299452197624	1.46372717466968e-08	1.5470470292278e-06
GO:0005201	extracellular matrix structural constituent	82/5347	168/18639	0.488095238095238	1.70144139570921	2.55646163091316e-08	2.50898448633906e-06
GO:0001221	transcription coregulator binding	60/5347	115/18639	0.521739130434783	1.81871996487262	9.49380303374024e-08	8.69632357890606e-06
GO:0106310	protein serine kinase activity	147/5347	361/18639	0.407202216066482	1.41945803352593	5.04650995873398e-07	4.33369042706281e-05
GO:0005096	GTPase activator activity	115/5347	271/18639	0.424354243542435	1.47924794190901	7.83773646928639e-07	6.3347352404703e-05
GO:0061630	ubiquitin protein ligase activity	143/5347	353/18639	0.405099150141643	1.41212699822145	1.01721667523834e-06	7.76475395431935e-05
GO:0031267	small GTPase binding	118/5347	283/18639	0.416961130742049	1.45347643835816	1.64497421773155e-06	0.000118957609219113
GO:0051020	GTPase binding	128/5347	315/18639	0.406349206349206	1.41648454407011	3.0467270044331e-06	0.000209310145204554
GO:0051018	protein kinase A binding	31/5347	53/18639	0.584905660377358	2.03891090401601	5.56569496536727e-06	0.000364155470591173
GO:0001217	DNA-binding transcription repressor activity	113/5347	278/18639	0.406474820143885	1.41692241867624	1.10503830794131e-05	0.000690146652323346
GO:0005518	collagen binding	38/5347	72/18639	0.527777777777778	1.83976996446606	1.45414191976266e-05	0.000868691738153869
GO:0061665	SUMO ligase activity	12/5347	14/18639	0.857142857142857	2.98789708514788	1.51739500223113e-05	0.000868708638777324
GO:0019789	SUMO transferase activity	19/5347	28/18639	0.678571428571429	2.36541852574207	1.95470228108531e-05	0.00104317991970776
GO:0019838	growth factor binding	62/5347	136/18639	0.455882352941176	1.58915114577718	1.97399402564787e-05	0.00104317991970776
GO:0031625	ubiquitin protein ligase binding	120/5347	302/18639	0.397350993377483	1.38511785404206	2.102480268986e-05	0.0010699288479951
GO:0050431	transforming growth factor beta binding	17/5347	24/18639	0.708333333333333	2.46916495230971	2.27967073017886e-05	0.00111866699402348
GO:0050321	tau-protein kinase activity	16/5347	22/18639	0.727272727272727	2.53518540558002	2.3657492343311e-05	0.00112087567171411
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	108/5347	268/18639	0.402985074626866	1.40475758480833	2.64598132293097e-05	0.00121185944590238
GO:0044389	ubiquitin-like protein ligase binding	126/5347	322/18639	0.391304347826087	1.36403997365447	3.085665053735e-05	0.00136764638188126
GO:0042393	histone binding	100/5347	247/18639	0.404858299595142	1.41128742213463	4.14944131419338e-05	0.00169828773788545
GO:0046915	transition metal ion transmembrane transporter activity	26/5347	45/18639	0.577777777777778	2.01406396109968	4.23584393447938e-05	0.00169828773788545
GO:0035173	histone kinase activity	138/5347	360/18639	0.383333333333333	1.33625397419114	4.32081605971739e-05	0.00169828773788545
GO:0140996	histone H3 kinase activity	137/5347	357/18639	0.38375350140056	1.33771862962503	4.32606046768492e-05	0.00169828773788545
GO:0141003	histone H2AX kinase activity	135/5347	354/18639	0.38135593220339	1.32936099127342	6.87723642420139e-05	0.00262481190190353
GO:0042826	histone deacetylase binding	57/5347	127/18639	0.448818897637795	1.5645287886798	7.18549588403356e-05	0.00266834360666544
GO:0001223	transcription coactivator binding	25/5347	44/18639	0.568181818181818	1.98061359810939	8.67064055458831e-05	0.00313512108473798
GO:0140030	modification-dependent protein binding	73/5347	173/18639	0.421965317919075	1.47092043401789	9.362243802396e-05	0.00329839050884413
GO:0070063	RNA polymerase binding	31/5347	59/18639	0.525423728813559	1.83156403242116	9.76861411103918e-05	0.00335551894714196
GO:0005085	guanyl-nucleotide exchange factor activity	92/5347	230/18639	0.4	1.39435197306901	0.000137887679411822	0.00462091881736204
GO:0005024	transforming growth factor beta receptor activity	12/5347	16/18639	0.75	2.61440994950439	0.000164862906213834	0.00539337221756686
GO:0048156	tau protein binding	24/5347	43/18639	0.558139534883721	1.94560740428234	0.000174730335949668	0.00558324375801962
GO:0140296	general transcription initiation factor binding	28/5347	53/18639	0.528301886792453	1.84159694556284	0.000185634821058693	0.00579686918487829
GO:0032182	ubiquitin-like protein binding	53/5347	120/18639	0.441666666666667	1.5395969702637	0.000209089376769123	0.00638419563735057
GO:0019902	phosphatase binding	77/5347	190/18639	0.405263157894737	1.41269870955676	0.000288255193924804	0.00861005731418872
GO:0001098	basal transcription machinery binding	30/5347	60/18639	0.5	1.74293996633626	0.00039248188531356	0.010877136107141
GO:0001099	basal RNA polymerase II transcription machinery binding	30/5347	60/18639	0.5	1.74293996633626	0.00039248188531356	0.010877136107141
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	30/5347	60/18639	0.5	1.74293996633626	0.00039248188531356	0.010877136107141
GO:0097493	structural molecule activity conferring elasticity	9/5347	11/18639	0.818181818181818	2.85208358127752	0.000397137938830131	0.010877136107141
GO:0046875	ephrin receptor binding	17/5347	28/18639	0.607142857142857	2.11642710197975	0.000407392481455459	0.010877136107141
GO:0140034	methylation-dependent protein binding	36/5347	76/18639	0.473684210526316	1.65120628389751	0.000418746319149428	0.010877136107141
GO:0016922	nuclear receptor binding	58/5347	137/18639	0.423357664233577	1.47577398609494	0.000421104985775899	0.010877136107141
GO:0004713	protein tyrosine kinase activity	59/5347	140/18639	0.421428571428571	1.46904940019771	0.000435170633775158	0.010877136107141
GO:0017154	semaphorin receptor activity	10/5347	13/18639	0.769230769230769	2.68144610205579	0.000435402100358629	0.010877136107141
GO:0005160	transforming growth factor beta receptor binding	16/5347	26/18639	0.615384615384615	2.14515688164463	0.000487264270112273	0.0117456334584958
GO:0050750	low-density lipoprotein particle receptor binding	16/5347	26/18639	0.615384615384615	2.14515688164463	0.000487264270112273	0.0117456334584958
GO:0034212	protein N-acetyltransferase activity	27/5347	53/18639	0.509433962264151	1.77582562607846	0.000517685236126094	0.0120717419293971
GO:0035064	methylated histone binding	35/5347	74/18639	0.472972972972973	1.64872699518295	0.000518364464217197	0.0120717419293971
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	14/5347	22/18639	0.636363636363636	2.21828722988252	0.000683029662695777	0.0156413792757333
GO:0043130	ubiquitin binding	44/5347	100/18639	0.44	1.53378717037591	0.000763540104870912	0.0171984279359448
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	12/5347	18/18639	0.666666666666667	2.32391995511502	0.000916641020068837	0.0199915041519775
GO:0070064	proline-rich region binding	12/5347	18/18639	0.666666666666667	2.32391995511502	0.000916641020068837	0.0199915041519775
GO:0061733	protein-lysine-acetyltransferase activity	24/5347	47/18639	0.51063829787234	1.78002379540725	0.000998106746911752	0.0214281042227617
GO:0000030	mannosyltransferase activity	15/5347	25/18639	0.6	2.09152795960352	0.00106507306458308	0.0225140060113409
GO:0016757	glycosyltransferase activity	100/5347	267/18639	0.374531835205993	1.30557300849158	0.00113519599708567	0.0236327166666016
GO:0140857	histone H3T45 kinase activity	93/5347	246/18639	0.378048780487805	1.31783265747376	0.00118085227880303	0.0242162840459009
GO:0004197	cysteine-type endopeptidase activity	39/5347	88/18639	0.443181818181818	1.54487860652532	0.00125451573900576	0.024278175250458
GO:0008080	N-acetyltransferase activity	32/5347	69/18639	0.463768115942029	1.61663996877566	0.00133654065684436	0.024278175250458
GO:0035402	histone H3T11 kinase activity	93/5347	247/18639	0.376518218623482	1.3124973025852	0.0013677073428741	0.024278175250458
GO:0035403	histone H3T6 kinase activity	93/5347	247/18639	0.376518218623482	1.3124973025852	0.0013677073428741	0.024278175250458
GO:0035091	phosphatidylinositol binding	105/5347	284/18639	0.369718309859155	1.28879363707963	0.00143897102542052	0.024278175250458
GO:0051019	mitogen-activated protein kinase binding	16/5347	28/18639	0.571428571428571	1.99193139009859	0.00150664349197479	0.024278175250458
GO:0004676	3-phosphoinositide-dependent protein kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0004711	ribosomal protein S6 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0035175	histone H3S10 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0035979	histone H2AXS139 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0044022	histone H3S28 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0044023	histone H4S1 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0044024	histone H2AS1 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0044025	histone H2BS14 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0072354	histone H3T3 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0072371	histone H2AS121 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0072518	Rho-dependent protein serine/threonine kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0140823	histone H2BS36 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0140855	histone H3S57 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0140995	histone H2A kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0140997	histone H4 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0140998	histone H2B kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:1990244	histone H2AT120 kinase activity	92/5347	245/18639	0.375510204081633	1.30898348492193	0.00159027348802127	0.024278175250458
GO:0000149	SNARE binding	45/5347	106/18639	0.424528301886792	1.47985468839871	0.00164614247301338	0.0248549423947296
GO:0019199	transmembrane receptor protein kinase activity	35/5347	78/18639	0.448717948717949	1.56417689286588	0.00167473986733635	0.0250118758447842
GO:0004677	DNA-dependent protein kinase activity	92/5347	246/18639	0.373983739837398	1.30366241384501	0.00183486278183997	0.0265209787425683
GO:0042800	histone H3K4 methyltransferase activity	12/5347	19/18639	0.631578947368421	2.20160837853002	0.00183945605008245	0.0265209787425683
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	91/5347	243/18639	0.374485596707819	1.30541182663868	0.00184737895446098	0.0265209787425683
GO:0034237	protein kinase A regulatory subunit binding	15/5347	26/18639	0.576923076923077	2.01108457654184	0.00185299414795237	0.0265209787425683
GO:0140318	protein transporter activity	21/5347	41/18639	0.51219512195122	1.78545069722251	0.00193514579457992	0.0274112404304413
GO:0070325	lipoprotein particle receptor binding	17/5347	31/18639	0.548387096774194	1.91161157598171	0.00198994098889393	0.0277999465566668
GO:0005484	SNAP receptor activity	19/5347	36/18639	0.527777777777778	1.83976996446606	0.00200305291783843	0.0277999465566668
GO:0035035	histone acetyltransferase binding	14/5347	24/18639	0.583333333333333	2.03342996072564	0.00227512364402576	0.031260198868914
GO:0004679	AMP-activated protein kinase activity	92/5347	248/18639	0.370967741935484	1.29314900728174	0.00242572847844667	0.032999514152334
GO:0004402	histone acetyltransferase activity	21/5347	42/18639	0.5	1.74293996633626	0.0028347567882273	0.0378013506807527
GO:0043175	RNA polymerase core enzyme binding	21/5347	42/18639	0.5	1.74293996633626	0.0028347567882273	0.0378013506807527
GO:0070123	transforming growth factor beta receptor activity, type III	9/5347	13/18639	0.692307692307692	2.41330149185021	0.00286123760611228	0.0378013506807527
GO:0048185	activin binding	8/5347	11/18639	0.727272727272727	2.53518540558002	0.00313490297142199	0.0406354404031492
GO:0048407	platelet-derived growth factor binding	8/5347	11/18639	0.727272727272727	2.53518540558002	0.00313490297142199	0.0406354404031492
GO:0032266	phosphatidylinositol-3-phosphate binding	23/5347	48/18639	0.479166666666667	1.67031746773892	0.00365955939418418	0.0469928468000847
GO:0010485	histone H4 acetyltransferase activity	18/5347	35/18639	0.514285714285714	1.79273825108873	0.00377914409784317	0.0476380182608854
GO:0140566	histone reader activity	18/5347	35/18639	0.514285714285714	1.79273825108873	0.00377914409784317	0.0476380182608854
GO:0043995	histone H4K5 acetyltransferase activity	16/5347	30/18639	0.533333333333333	1.85913596409201	0.00389892253556909	0.0478314246774279
GO:0043996	histone H4K8 acetyltransferase activity	16/5347	30/18639	0.533333333333333	1.85913596409201	0.00389892253556909	0.0478314246774279
GO:0043997	histone H4K12 acetyltransferase activity	16/5347	30/18639	0.533333333333333	1.85913596409201	0.00389892253556909	0.0478314246774279
GO:0051213	dioxygenase activity	39/5347	93/18639	0.419354838709677	1.46182061692719	0.00418603634389543	0.0508992383762153
GO:0016407	acetyltransferase activity	40/5347	96/18639	0.416666666666667	1.45244997194689	0.00430322799637405	0.0518652216405083
GO:0140463	chromatin-protein adaptor activity	25/5347	54/18639	0.462962962962963	1.61383330216321	0.00444031652711975	0.0530521296370655
GO:0036408	histone H3K14 acetyltransferase activity	15/5347	28/18639	0.535714285714286	1.86743567821742	0.00487626745635741	0.0572648844874794
GO:0046966	nuclear thyroid hormone receptor binding	15/5347	28/18639	0.535714285714286	1.86743567821742	0.00487626745635741	0.0572648844874794
GO:0097027	ubiquitin-protein transferase activator activity	10/5347	16/18639	0.625	2.17867495792033	0.00499648044308046	0.0581793570236657
GO:0016791	phosphatase activity	98/5347	273/18639	0.358974358974359	1.2513415142927	0.005538769159656	0.0636074439313586
GO:0000993	RNA polymerase II complex binding	18/5347	36/18639	0.5	1.74293996633626	0.00555523527784791	0.0636074439313586
GO:0035401	histone H3Y41 kinase activity	46/5347	115/18639	0.4	1.39435197306901	0.00585604624655915	0.0659525208423956
GO:0140801	histone H2AXY142 kinase activity	46/5347	115/18639	0.4	1.39435197306901	0.00585604624655915	0.0659525208423956
GO:0034236	protein kinase A catalytic subunit binding	9/5347	14/18639	0.642857142857143	2.24092281386091	0.00597635110127057	0.0662218259124658
GO:0042813	Wnt receptor activity	9/5347	14/18639	0.642857142857143	2.24092281386091	0.00597635110127057	0.0662218259124658
GO:0070412	R-SMAD binding	14/5347	26/18639	0.538461538461538	1.87701227143905	0.006104414199423	0.0670997208800576
GO:0140938	histone H3 methyltransferase activity	22/5347	47/18639	0.468085106382979	1.63168847912331	0.00628761614632801	0.0685649570242435
GO:0005025	transforming growth factor beta receptor activity, type I	8/5347	12/18639	0.666666666666667	2.32391995511502	0.00704108286385416	0.0738507469842413
GO:0005026	transforming growth factor beta receptor activity, type II	8/5347	12/18639	0.666666666666667	2.32391995511502	0.00704108286385416	0.0738507469842413
GO:0016361	activin receptor activity, type I	8/5347	12/18639	0.666666666666667	2.32391995511502	0.00704108286385416	0.0738507469842413
GO:0016362	activin receptor activity, type II	8/5347	12/18639	0.666666666666667	2.32391995511502	0.00704108286385416	0.0738507469842413
GO:0017002	activin receptor activity	8/5347	12/18639	0.666666666666667	2.32391995511502	0.00704108286385416	0.0738507469842413
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	15/5347	29/18639	0.517241379310345	1.80304134448579	0.00745223462379892	0.0764132117395502
GO:0010484	histone H3 acetyltransferase activity	15/5347	29/18639	0.517241379310345	1.80304134448579	0.00745223462379892	0.0764132117395502
GO:0097472	cyclin-dependent protein kinase activity	15/5347	29/18639	0.517241379310345	1.80304134448579	0.00745223462379892	0.0764132117395502
GO:0005381	iron ion transmembrane transporter activity	7/5347	10/18639	0.7	2.44011595287077	0.00808991277981331	0.0793967154247392
GO:0005522	profilin binding	7/5347	10/18639	0.7	2.44011595287077	0.00808991277981331	0.0793967154247392
GO:0043422	protein kinase B binding	7/5347	10/18639	0.7	2.44011595287077	0.00808991277981331	0.0793967154247392
GO:0099122	RNA polymerase II C-terminal domain binding	7/5347	10/18639	0.7	2.44011595287077	0.00808991277981331	0.0793967154247392
GO:0140999	histone H3K4 trimethyltransferase activity	7/5347	10/18639	0.7	2.44011595287077	0.00808991277981331	0.0793967154247392
GO:1990757	ubiquitin ligase activator activity	7/5347	10/18639	0.7	2.44011595287077	0.00808991277981331	0.0793967154247392
GO:0005539	glycosaminoglycan binding	87/5347	242/18639	0.359504132231405	1.2531882402583	0.00818809847334304	0.0797904063998109
GO:0004177	aminopeptidase activity	19/5347	40/18639	0.475	1.65579296801945	0.0088920677173569	0.0860401481947069
GO:0004721	phosphoprotein phosphatase activity	65/5347	175/18639	0.371428571428571	1.29475540356408	0.00929485207391858	0.0881905438001404
GO:0042578	phosphoric ester hydrolase activity	125/5347	363/18639	0.34435261707989	1.20037187764205	0.00930619107432887	0.0881905438001404
GO:0005385	zinc ion transmembrane transporter activity	14/5347	27/18639	0.518518518518518	1.80749329842279	0.00937104759448362	0.0881905438001404
GO:0023026	MHC class II protein complex binding	14/5347	27/18639	0.518518518518518	1.80749329842279	0.00937104759448362	0.0881905438001404
GO:0004712	protein serine/threonine/tyrosine kinase activity	20/5347	43/18639	0.465116279069767	1.62133950356862	0.00976816725689687	0.0913024612991584
GO:0016758	hexosyltransferase activity	72/5347	197/18639	0.365482233502538	1.27402718351483	0.00991326282028173	0.0920325886153183
GO:0042809	nuclear vitamin D receptor binding	9/5347	15/18639	0.6	2.09152795960352	0.0111617397557883	0.10156443989704
GO:0050780	dopamine receptor binding	9/5347	15/18639	0.6	2.09152795960352	0.0111617397557883	0.10156443989704
GO:0120283	protein serine/threonine kinase binding	9/5347	15/18639	0.6	2.09152795960352	0.0111617397557883	0.10156443989704
GO:0017025	TBP-class protein binding	13/5347	25/18639	0.52	1.81265756498971	0.0118038749589152	0.105315092165906
GO:0042974	nuclear retinoic acid receptor binding	13/5347	25/18639	0.52	1.81265756498971	0.0118038749589152	0.105315092165906
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	13/5347	25/18639	0.52	1.81265756498971	0.0118038749589152	0.105315092165906
GO:0071889	14-3-3 protein binding	16/5347	33/18639	0.484848484848485	1.69012360372001	0.012530762433942	0.11107914570475
GO:0030971	receptor tyrosine kinase binding	33/5347	81/18639	0.407407407407407	1.42017330590362	0.0131130488879895	0.115189685718118
GO:0001046	core promoter sequence-specific DNA binding	20/5347	44/18639	0.454545454545455	1.58449087848751	0.0131621402166991	0.115189685718118
GO:0005338	nucleotide-sugar transmembrane transporter activity	8/5347	13/18639	0.615384615384615	2.14515688164463	0.0137288352762411	0.118649677459178
GO:0019905	syntaxin binding	26/5347	61/18639	0.426229508196721	1.48578488933583	0.0137302028500795	0.118649677459178
GO:1901681	sulfur compound binding	96/5347	275/18639	0.349090909090909	1.21688899467841	0.0139531691739973	0.119640047738082
GO:0008238	exopeptidase activity	40/5347	102/18639	0.392156862745098	1.36701173830295	0.0140189575588291	0.119640047738082
GO:0008201	heparin binding	63/5347	172/18639	0.366279069767442	1.27680485906029	0.0143150304039429	0.121412665277886
GO:0050840	extracellular matrix binding	28/5347	67/18639	0.417910447761194	1.45678564350494	0.0146025685044927	0.122413858940695
GO:0015605	organophosphate ester transmembrane transporter activity	22/5347	50/18639	0.44	1.53378717037591	0.0148549396665692	0.122413858940695
GO:0005158	insulin receptor binding	12/5347	23/18639	0.521739130434783	1.81871996487262	0.0148970765735608	0.122413858940695
GO:0044013	histone H2B acetyltransferase activity	12/5347	23/18639	0.521739130434783	1.81871996487262	0.0148970765735608	0.122413858940695
GO:0070577	lysine-acetylated histone binding	12/5347	23/18639	0.521739130434783	1.81871996487262	0.0148970765735608	0.122413858940695
GO:0097110	scaffold protein binding	29/5347	70/18639	0.414285714285714	1.44415025782148	0.0149676334075959	0.122413858940695
GO:0035615	clathrin adaptor activity	10/5347	18/18639	0.555555555555556	1.93659996259585	0.0151591972184667	0.123246964367889
GO:0017147	Wnt-protein binding	15/5347	31/18639	0.483870967741935	1.68671609645445	0.0157590253307846	0.127370004732342
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	7/5347	11/18639	0.636363636363636	2.21828722988252	0.0167611799444981	0.133120585223933
GO:0005114	type II transforming growth factor beta receptor binding	7/5347	11/18639	0.636363636363636	2.21828722988252	0.0167611799444981	0.133120585223933
GO:0032794	GTPase activating protein binding	7/5347	11/18639	0.636363636363636	2.21828722988252	0.0167611799444981	0.133120585223933
GO:0005178	integrin binding	59/5347	161/18639	0.366459627329193	1.27743426104149	0.0171312267865796	0.135277618418163
GO:0032934	sterol binding	28/5347	68/18639	0.411764705882353	1.4353623252181	0.018168387466554	0.142647796451687
GO:0051010	microtubule plus-end binding	11/5347	21/18639	0.523809523809524	1.82593710759037	0.0188428710070843	0.146522912715177
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	48/5347	128/18639	0.375	1.3072049747522	0.0190399040974779	0.146522912715177
GO:0005159	insulin-like growth factor receptor binding	9/5347	16/18639	0.5625	1.9608074621283	0.0190885017292697	0.146522912715177
GO:0070411	I-SMAD binding	9/5347	16/18639	0.5625	1.9608074621283	0.0190885017292697	0.146522912715177
GO:0019903	protein phosphatase binding	53/5347	144/18639	0.368055555555556	1.28299747521975	0.020991049219941	0.159346417835353
GO:0019955	cytokine binding	53/5347	144/18639	0.368055555555556	1.28299747521975	0.020991049219941	0.159346417835353
GO:0001091	RNA polymerase II general transcription initiation factor binding	12/5347	24/18639	0.5	1.74293996633626	0.022144395397554	0.165360865631735
GO:0043998	histone H2A acetyltransferase activity	12/5347	24/18639	0.5	1.74293996633626	0.022144395397554	0.165360865631735
GO:0140033	acetylation-dependent protein binding	12/5347	24/18639	0.5	1.74293996633626	0.022144395397554	0.165360865631735
GO:0002039	p53 binding	28/5347	69/18639	0.405797101449275	1.41455997267871	0.0223885626888664	0.166280460186499
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	80/5347	229/18639	0.349344978165939	1.21777464896857	0.0226588714600435	0.167383276269354
GO:0005496	steroid binding	41/5347	108/18639	0.37962962962963	1.32334330777383	0.023192413100431	0.170408425668407
GO:0001222	transcription corepressor binding	21/5347	49/18639	0.428571428571429	1.49394854257394	0.0236277360994995	0.172218597281779
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	159/5347	484/18639	0.328512396694215	1.14515477127052	0.0237149046742005	0.172218597281779
GO:0005161	platelet-derived growth factor receptor binding	8/5347	14/18639	0.571428571428571	1.99193139009859	0.0240654808428687	0.172218597281779
GO:0005545	1-phosphatidylinositol binding	8/5347	14/18639	0.571428571428571	1.99193139009859	0.0240654808428687	0.172218597281779
GO:0098821	BMP receptor activity	8/5347	14/18639	0.571428571428571	1.99193139009859	0.0240654808428687	0.172218597281779
GO:0019207	kinase regulator activity	98/5347	287/18639	0.341463414634146	1.19030046481501	0.0243718124017385	0.173507099689061
GO:0016410	N-acyltransferase activity	36/5347	94/18639	0.382978723404255	1.33501784655544	0.0278237694210773	0.183780963813806
GO:0043014	alpha-tubulin binding	19/5347	44/18639	0.431818181818182	1.50526633456314	0.0280373223649637	0.183780963813806
GO:0030021	extracellular matrix structural constituent conferring compression resistance	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0032931	histone H3K56 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0043992	histone H3K9 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0043993	histone H3K18 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0043994	histone H3K23 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0043999	histone H2AK5 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0044012	histone H2AK9 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0044014	histone H2BK5 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0044015	histone H2BK12 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0044016	histone H3K4 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0044017	histone H3K27 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0044018	histone H3K36 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0046972	histone H4K16 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0140035	ubiquitin-like protein reader activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0140908	histone H3K122 acetyltransferase activity	11/5347	22/18639	0.5	1.74293996633626	0.0280887935959965	0.183780963813806
GO:0005165	neurotrophin receptor binding	7/5347	12/18639	0.583333333333333	2.03342996072564	0.0303693158573996	0.194263494280915
GO:0034452	dynactin binding	7/5347	12/18639	0.583333333333333	2.03342996072564	0.0303693158573996	0.194263494280915
GO:0035497	cAMP response element binding	7/5347	12/18639	0.583333333333333	2.03342996072564	0.0303693158573996	0.194263494280915
GO:0016805	dipeptidase activity	9/5347	17/18639	0.529411764705882	1.84546584670898	0.0303978539085857	0.194263494280915
GO:0032977	membrane insertase activity	9/5347	17/18639	0.529411764705882	1.84546584670898	0.0303978539085857	0.194263494280915
GO:0019211	phosphatase activator activity	12/5347	25/18639	0.48	1.67322236768281	0.0316894911870668	0.201580374495508
GO:1990841	promoter-specific chromatin binding	27/5347	68/18639	0.397058823529412	1.38409938503174	0.0329001307097047	0.208316956659605
GO:0048487	beta-tubulin binding	18/5347	42/18639	0.428571428571429	1.49394854257394	0.0346458737159818	0.218364360026417
GO:0031418	L-ascorbic acid binding	10/5347	20/18639	0.5	1.74293996633626	0.0357379204317125	0.224218733667457
GO:0008194	UDP-glycosyltransferase activity	52/5347	145/18639	0.358620689655172	1.25010866551015	0.0359640357416099	0.224611750495327
GO:0140767	enzyme-substrate adaptor activity	50/5347	139/18639	0.359712230215827	1.25391364484623	0.0370622696791728	0.228877815313243
GO:0001216	DNA-binding transcription activator activity	159/5347	491/18639	0.323828920570265	1.12882873583489	0.0383122415436962	0.228877815313243
GO:0004862	cAMP-dependent protein kinase inhibitor activity	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0008239	dipeptidyl-peptidase activity	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0042975	peroxisome proliferator activated receptor binding	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0045322	unmethylated CpG binding	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0070097	delta-catenin binding	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:1905394	retromer complex binding	6/5347	10/18639	0.6	2.09152795960352	0.0383346302504955	0.228877815313243
GO:0005041	low-density lipoprotein particle receptor activity	8/5347	15/18639	0.533333333333333	1.85913596409201	0.0388126135138177	0.228877815313243
GO:0141050	histone H3K deacetylase activity	8/5347	15/18639	0.533333333333333	1.85913596409201	0.0388126135138177	0.228877815313243
GO:0141051	histone H4K deacetylase activity	8/5347	15/18639	0.533333333333333	1.85913596409201	0.0388126135138177	0.228877815313243
GO:0030332	cyclin binding	15/5347	34/18639	0.441176470588235	1.53788820559082	0.0395064991487771	0.231974059104358
GO:0019003	GDP binding	29/5347	75/18639	0.386666666666667	1.34787357396671	0.0396779652613864	0.231989464975085
GO:0042171	lysophosphatidic acid acyltransferase activity	11/5347	23/18639	0.478260869565217	1.6671599677999	0.0401812008665628	0.232949240466908
GO:0071617	lysophospholipid acyltransferase activity	11/5347	23/18639	0.478260869565217	1.6671599677999	0.0401812008665628	0.232949240466908
GO:0023023	MHC protein complex binding	16/5347	37/18639	0.432432432432432	1.50740753845298	0.0413136078844313	0.238507971568103
GO:0070006	metalloaminopeptidase activity	12/5347	26/18639	0.461538461538462	1.60886766123347	0.0438490530173462	0.252086187639471
GO:0030291	protein serine/threonine kinase inhibitor activity	19/5347	46/18639	0.41304347826087	1.43981997219083	0.0450151982679373	0.257712010083941
GO:0005543	phospholipid binding	160/5347	497/18639	0.321931589537223	1.12221486766118	0.0455648724167374	0.259776492533598
GO:0016763	pentosyltransferase activity	20/5347	49/18639	0.408163265306122	1.4228081357847	0.0457972434203803	0.260022365535547
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	44/5347	122/18639	0.360655737704918	1.25720259866878	0.0460655286268263	0.260469285322055
GO:0005080	protein kinase C binding	21/5347	52/18639	0.403846153846154	1.40775920357929	0.0464017843308322	0.261295293731818
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	7/5347	13/18639	0.538461538461538	1.87701227143905	0.0497832098687512	0.275815041772839
GO:0046974	histone H3K9 methyltransferase activity	7/5347	13/18639	0.538461538461538	1.87701227143905	0.0497832098687512	0.275815041772839
GO:0046975	histone H3K36 methyltransferase activity	7/5347	13/18639	0.538461538461538	1.87701227143905	0.0497832098687512	0.275815041772839
GO:0070700	BMP receptor binding	7/5347	13/18639	0.538461538461538	1.87701227143905	0.0497832098687512	0.275815041772839
GO:0035591	signaling adaptor activity	46/5347	129/18639	0.356589147286822	1.24302695273594	0.0506649438178179	0.279572822512778
GO:0005123	death receptor binding	10/5347	21/18639	0.476190476190476	1.65994282508216	0.0510970562722837	0.279710578956645
GO:0140312	cargo adaptor activity	10/5347	21/18639	0.476190476190476	1.65994282508216	0.0510970562722837	0.279710578956645
GO:1990782	protein tyrosine kinase binding	42/5347	117/18639	0.358974358974359	1.2513415142927	0.0540358070278601	0.294623804985237
GO:0030165	PDZ domain binding	31/5347	83/18639	0.373493975903614	1.30195515557649	0.0544052064535131	0.295465429514336
GO:0030020	extracellular matrix structural constituent conferring tensile strength	18/5347	44/18639	0.409090909090909	1.42604179063876	0.055099924597014	0.297634352099323
GO:0044325	transmembrane transporter binding	48/5347	136/18639	0.352941176470588	1.23031056447266	0.0552378164376472	0.297634352099323
GO:0030145	manganese ion binding	26/5347	68/18639	0.382352941176471	1.33283644484538	0.0564844860595976	0.300901571864658
GO:1901505	carbohydrate derivative transmembrane transporter activity	21/5347	53/18639	0.39622641509434	1.38119770917213	0.0566819242111182	0.300901571864658
GO:0038024	cargo receptor activity	25/5347	65/18639	0.384615384615385	1.34072305102789	0.0567201652932653	0.300901571864658
GO:0160215	deacylase activity	25/5347	65/18639	0.384615384615385	1.34072305102789	0.0567201652932653	0.300901571864658
GO:0005521	lamin binding	8/5347	16/18639	0.5	1.74293996633626	0.0585367252983656	0.308158852720131
GO:0015923	mannosidase activity	8/5347	16/18639	0.5	1.74293996633626	0.0585367252983656	0.308158852720131
GO:0005044	scavenger receptor activity	12/5347	27/18639	0.444444444444444	1.54927997007668	0.0588844985358679	0.308806492321689
GO:0001968	fibronectin binding	13/5347	30/18639	0.433333333333333	1.51054797082476	0.0615905943901557	0.319665973873223
GO:0015215	nucleotide transmembrane transporter activity	13/5347	30/18639	0.433333333333333	1.51054797082476	0.0615905943901557	0.319665973873223
GO:0019210	kinase inhibitor activity	33/5347	90/18639	0.366666666666667	1.27815597531326	0.061653190011939	0.319665973873223
GO:0004860	protein kinase inhibitor activity	31/5347	84/18639	0.369047619047619	1.28645568943867	0.0632390039708757	0.32205141178361
GO:0140311	protein sequestering activity	14/5347	33/18639	0.424242424242424	1.47885815325501	0.0636964037296732	0.32205141178361
GO:0140416	transcription regulator inhibitor activity	14/5347	33/18639	0.424242424242424	1.47885815325501	0.0636964037296732	0.32205141178361
GO:0003953	NAD+ nucleosidase activity	6/5347	11/18639	0.545454545454545	1.90138905418501	0.0642227706176922	0.32205141178361
GO:0004954	prostanoid receptor activity	6/5347	11/18639	0.545454545454545	1.90138905418501	0.0642227706176922	0.32205141178361
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/5347	11/18639	0.545454545454545	1.90138905418501	0.0642227706176922	0.32205141178361
GO:0034713	type I transforming growth factor beta receptor binding	6/5347	11/18639	0.545454545454545	1.90138905418501	0.0642227706176922	0.32205141178361
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	6/5347	11/18639	0.545454545454545	1.90138905418501	0.0642227706176922	0.32205141178361
GO:0180030	inositol phosphate kinase activity	6/5347	11/18639	0.545454545454545	1.90138905418501	0.0642227706176922	0.32205141178361
GO:0005346	purine ribonucleotide transmembrane transporter activity	9/5347	19/18639	0.473684210526316	1.65120628389751	0.0652029752497296	0.322788347205466
GO:0140036	ubiquitin-modified protein reader activity	9/5347	19/18639	0.473684210526316	1.65120628389751	0.0652029752497296	0.322788347205466
GO:0016409	palmitoyltransferase activity	15/5347	36/18639	0.416666666666667	1.45244997194689	0.0653094326951379	0.322788347205466
GO:0055106	ubiquitin-protein transferase regulator activity	15/5347	36/18639	0.416666666666667	1.45244997194689	0.0653094326951379	0.322788347205466
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	16/5347	39/18639	0.41025641025641	1.43010458776309	0.0665156472045841	0.326792070023362
GO:0004722	protein serine/threonine phosphatase activity	37/5347	103/18639	0.359223300970874	1.25220929620275	0.0665951816641494	0.326792070023362
GO:0016859	cis-trans isomerase activity	17/5347	42/18639	0.404761904761905	1.41095140131983	0.0673842220852063	0.329487263861472
GO:0004714	transmembrane receptor protein tyrosine kinase activity	23/5347	60/18639	0.383333333333333	1.33625397419114	0.0680310741441896	0.330123209472291
GO:0015932	nucleobase-containing compound transmembrane transporter activity	22/5347	57/18639	0.385964912280702	1.34542734243501	0.0683058774996765	0.330123209472291
GO:0015485	cholesterol binding	21/5347	54/18639	0.388888888888889	1.35561997381709	0.0684611987792479	0.330123209472291
GO:0005048	signal sequence binding	20/5347	51/18639	0.392156862745098	1.36701173830295	0.0684753382093181	0.330123209472291
GO:0004407	histone deacetylase activity	10/5347	22/18639	0.454545454545455	1.58449087848751	0.0702706085025227	0.336417477639255
GO:0033558	protein lysine deacetylase activity	10/5347	22/18639	0.454545454545455	1.58449087848751	0.0702706085025227	0.336417477639255
GO:0019706	protein-cysteine S-palmitoyltransferase activity	11/5347	25/18639	0.44	1.53378717037591	0.0741066733288996	0.352327228906256
GO:0019707	protein-cysteine S-acyltransferase activity	11/5347	25/18639	0.44	1.53378717037591	0.0741066733288996	0.352327228906256
GO:0046030	inositol trisphosphate phosphatase activity	7/5347	14/18639	0.5	1.74293996633626	0.0755009388946337	0.357718241521471
GO:0019887	protein kinase regulator activity	84/5347	255/18639	0.329411764705882	1.14828986017448	0.0759058393940338	0.358400767448118
GO:0008234	cysteine-type peptidase activity	63/5347	187/18639	0.336898395721925	1.17438735699663	0.0766269055724976	0.360566329645931
GO:0045499	chemorepellent activity	12/5347	28/18639	0.428571428571429	1.49394854257394	0.0769840158970937	0.361010368063504
GO:0008237	metallopeptidase activity	62/5347	184/18639	0.33695652173913	1.17458997731357	0.0782251494921613	0.363520630118613
GO:0008170	N-methyltransferase activity	35/5347	98/18639	0.357142857142857	1.24495711881162	0.0783698351000096	0.363520630118613
GO:0002020	protease binding	47/5347	136/18639	0.345588235294118	1.20467909437948	0.0789175438897049	0.363520630118613
GO:0140789	histone phosphatase activity	47/5347	136/18639	0.345588235294118	1.20467909437948	0.0789175438897049	0.363520630118613
GO:0042054	histone methyltransferase activity	25/5347	67/18639	0.373134328358209	1.30070146741512	0.0789351636521606	0.363520630118613
GO:0140457	protein demethylase activity	13/5347	31/18639	0.419354838709677	1.46182061692719	0.0791067455643853	0.363520630118613
GO:0008276	protein methyltransferase activity	34/5347	95/18639	0.357894736842105	1.24757808116701	0.0797304033385932	0.365165247290757
GO:0008175	tRNA methyltransferase activity	14/5347	34/18639	0.411764705882353	1.4353623252181	0.0806293369363008	0.36805551146338
GO:0043178	alcohol binding	33/5347	92/18639	0.358695652173913	1.25036997584993	0.0810996119114091	0.368976380020782
GO:0043394	proteoglycan binding	15/5347	37/18639	0.405405405405405	1.41319456729967	0.0816702223388011	0.369120264150071
GO:0140313	molecular sequestering activity	21/5347	55/18639	0.381818181818182	1.33097233792951	0.0818081352411906	0.369120264150071
GO:0032451	demethylase activity	16/5347	40/18639	0.4	1.39435197306901	0.0823213653234657	0.369120264150071
GO:0000287	magnesium ion binding	76/5347	230/18639	0.330434782608696	1.15185597775266	0.0826072629748146	0.369120264150071
GO:0008375	acetylglucosaminyltransferase activity	17/5347	43/18639	0.395348837209302	1.37813857803332	0.0826550357252198	0.369120264150071
GO:0008429	phosphatidylethanolamine binding	8/5347	17/18639	0.470588235294118	1.64041408596354	0.0835490554226143	0.369120264150071
GO:0008484	sulfuric ester hydrolase activity	8/5347	17/18639	0.470588235294118	1.64041408596354	0.0835490554226143	0.369120264150071
GO:0015278	intracellularly gated calcium channel activity	8/5347	17/18639	0.470588235294118	1.64041408596354	0.0835490554226143	0.369120264150071
GO:0046965	nuclear retinoid X receptor binding	8/5347	17/18639	0.470588235294118	1.64041408596354	0.0835490554226143	0.369120264150071
GO:1901981	phosphatidylinositol phosphate binding	62/5347	185/18639	0.335135135135135	1.16824084230106	0.0856741738555502	0.377295881017711
GO:0016004	phospholipase activator activity	9/5347	20/18639	0.45	1.56864596970264	0.0893107473735621	0.390805627042275
GO:0052745	inositol phosphate phosphatase activity	9/5347	20/18639	0.45	1.56864596970264	0.0893107473735621	0.390805627042275
GO:0140223	general transcription initiation factor activity	25/5347	68/18639	0.367647058823529	1.28157350465902	0.0919878831827201	0.400577753711376
GO:0000295	adenine nucleotide transmembrane transporter activity	10/5347	23/18639	0.434782608695652	1.51559997072719	0.0934163066840304	0.400577753711376
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	10/5347	23/18639	0.434782608695652	1.51559997072719	0.0934163066840304	0.400577753711376
GO:0017134	fibroblast growth factor binding	10/5347	23/18639	0.434782608695652	1.51559997072719	0.0934163066840304	0.400577753711376
GO:0003779	actin binding	140/5347	443/18639	0.316027088036117	1.10163248436604	0.0942476205039791	0.400577753711376
GO:0031593	polyubiquitin modification-dependent protein binding	22/5347	59/18639	0.372881355932203	1.29981963591179	0.095670391581907	0.400577753711376
GO:0015216	purine nucleotide transmembrane transporter activity	11/5347	26/18639	0.423076923076923	1.47479535613068	0.0962955948907056	0.400577753711376
GO:0050681	nuclear androgen receptor binding	11/5347	26/18639	0.423076923076923	1.47479535613068	0.0962955948907056	0.400577753711376
GO:0052742	phosphatidylinositol kinase activity	11/5347	26/18639	0.423076923076923	1.47479535613068	0.0962955948907056	0.400577753711376
GO:0097602	cullin family protein binding	11/5347	26/18639	0.423076923076923	1.47479535613068	0.0962955948907056	0.400577753711376
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	56/5347	167/18639	0.335329341317365	1.1689178217345	0.097248597954176	0.400577753711376
GO:0005078	MAP-kinase scaffold activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0005247	voltage-gated chloride channel activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0008603	cAMP-dependent protein kinase regulator activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0031543	peptidyl-proline dioxygenase activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0035014	phosphatidylinositol 3-kinase regulator activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0035251	UDP-glucosyltransferase activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/5347	12/18639	0.5	1.74293996633626	0.0980762253779847	0.400577753711376
GO:0016417	S-acyltransferase activity	12/5347	29/18639	0.413793103448276	1.44243307558863	0.0982494199423098	0.400577753711376
GO:0008378	galactosyltransferase activity	13/5347	32/18639	0.40625	1.41613872264821	0.09949353763822	0.400876542232021
GO:0022884	macromolecule transmembrane transporter activity	13/5347	32/18639	0.40625	1.41613872264821	0.09949353763822	0.400876542232021
GO:0120015	sterol transfer activity	13/5347	32/18639	0.40625	1.41613872264821	0.09949353763822	0.400876542232021
GO:0001727	lipid kinase activity	16/5347	41/18639	0.390243902439024	1.36034338836001	0.100361928192551	0.400876542232021
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	16/5347	41/18639	0.390243902439024	1.36034338836001	0.100361928192551	0.400876542232021
GO:0005109	frizzled binding	15/5347	38/18639	0.394736842105263	1.37600523658126	0.100445632432952	0.400876542232021
GO:0042162	telomeric DNA binding	15/5347	38/18639	0.394736842105263	1.37600523658126	0.100445632432952	0.400876542232021
GO:0019209	kinase activator activity	50/5347	148/18639	0.337837837837838	1.17766213941639	0.100656773704547	0.400876542232021
GO:0042277	peptide binding	81/5347	249/18639	0.325301204819277	1.13396094195371	0.101395132904488	0.402650036447301
GO:0004559	alpha-mannosidase activity	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0004953	icosanoid receptor activity	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0005523	tropomyosin binding	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0031005	filamin binding	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0051371	muscle alpha-actinin binding	7/5347	15/18639	0.466666666666667	1.62674396858051	0.107603223602848	0.418829544561792
GO:0008168	methyltransferase activity	67/5347	204/18639	0.32843137254902	1.14487233082872	0.108119990865235	0.419652167934555
GO:0140097	catalytic activity, acting on DNA	107/5347	336/18639	0.318452380952381	1.11008676427369	0.109950760088444	0.425555899609921
GO:0140597	protein carrier chaperone	62/5347	188/18639	0.329787234042553	1.14959870120051	0.110944248652428	0.428194937214707
GO:0019208	phosphatase regulator activity	40/5347	117/18639	0.341880341880342	1.19175382313591	0.112900732770964	0.434525509320182
GO:0008409	5'-3' exonuclease activity	8/5347	18/18639	0.444444444444444	1.54927997007668	0.113879091281742	0.435849224014243
GO:0030228	lipoprotein particle receptor activity	8/5347	18/18639	0.444444444444444	1.54927997007668	0.113879091281742	0.435849224014243
GO:0004725	protein tyrosine phosphatase activity	34/5347	98/18639	0.346938775510204	1.209386915417	0.115030738298364	0.439033984505424
GO:0005010	insulin-like growth factor receptor activity	19/5347	51/18639	0.372549019607843	1.2986611513878	0.116605877282762	0.440916419903129
GO:0005021	vascular endothelial growth factor receptor activity	19/5347	51/18639	0.372549019607843	1.2986611513878	0.116605877282762	0.440916419903129
GO:0005030	neurotrophin receptor activity	19/5347	51/18639	0.372549019607843	1.2986611513878	0.116605877282762	0.440916419903129
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	9/5347	21/18639	0.428571428571429	1.49394854257394	0.117971015699521	0.440916419903129
GO:0009931	calcium-dependent protein serine/threonine kinase activity	9/5347	21/18639	0.428571428571429	1.49394854257394	0.117971015699521	0.440916419903129
GO:0010314	phosphatidylinositol-5-phosphate binding	9/5347	21/18639	0.428571428571429	1.49394854257394	0.117971015699521	0.440916419903129
GO:0072542	protein phosphatase activator activity	9/5347	21/18639	0.428571428571429	1.49394854257394	0.117971015699521	0.440916419903129
GO:0140693	molecular condensate scaffold activity	18/5347	48/18639	0.375	1.3072049747522	0.118091151764448	0.440916419903129
GO:0061775	cohesin loader activity	51/5347	153/18639	0.333333333333333	1.16195997755751	0.118660130439932	0.44184016049991
GO:0015295	solute:proton symporter activity	10/5347	24/18639	0.416666666666667	1.45244997194689	0.120540016325129	0.445220382878298
GO:0050699	WW domain binding	10/5347	24/18639	0.416666666666667	1.45244997194689	0.120540016325129	0.445220382878298
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	10/5347	24/18639	0.416666666666667	1.45244997194689	0.120540016325129	0.445220382878298
GO:0008320	protein transmembrane transporter activity	11/5347	27/18639	0.407407407407407	1.42017330590362	0.122015723634657	0.445963458218272
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	14/5347	36/18639	0.388888888888889	1.35561997381709	0.122380456460573	0.445963458218272
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	14/5347	36/18639	0.388888888888889	1.35561997381709	0.122380456460573	0.445963458218272
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	14/5347	36/18639	0.388888888888889	1.35561997381709	0.122380456460573	0.445963458218272
GO:0032452	histone demethylase activity	12/5347	30/18639	0.4	1.39435197306901	0.122688636977079	0.445963458218272
GO:0035925	mRNA 3'-UTR AU-rich region binding	12/5347	30/18639	0.4	1.39435197306901	0.122688636977079	0.445963458218272
GO:0140104	molecular carrier activity	80/5347	249/18639	0.321285140562249	1.11996142415182	0.128053223182241	0.447379907290188
GO:0016853	isomerase activity	59/5347	180/18639	0.327777777777778	1.14259397793155	0.128482417883555	0.447379907290188
GO:0004445	inositol-polyphosphate 5-phosphatase activity	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0004955	prostaglandin receptor activity	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0005131	growth hormone receptor binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0008140	cAMP response element binding protein binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0032356	oxidized DNA binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0032395	MHC class II receptor activity	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0043295	glutathione binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0050815	phosphoserine residue binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0051880	G-quadruplex DNA binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0070513	death domain binding	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/5347	10/18639	0.5	1.74293996633626	0.128613583245724	0.447379907290188
GO:0051219	phosphoprotein binding	32/5347	93/18639	0.344086021505376	1.19944255747872	0.134551622193796	0.466853355793625
GO:0030159	signaling receptor complex adaptor activity	19/5347	52/18639	0.365384615384615	1.2736868984765	0.136374264861198	0.471985490980571
GO:0060590	ATPase regulator activity	18/5347	49/18639	0.36734693877551	1.28052732220623	0.138705707118193	0.47551391547096
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	6/5347	13/18639	0.461538461538462	1.60886766123347	0.139470238671613	0.47551391547096
GO:0019855	calcium channel inhibitor activity	6/5347	13/18639	0.461538461538462	1.60886766123347	0.139470238671613	0.47551391547096
GO:0039706	co-receptor binding	6/5347	13/18639	0.461538461538462	1.60886766123347	0.139470238671613	0.47551391547096
GO:0051011	microtubule minus-end binding	6/5347	13/18639	0.461538461538462	1.60886766123347	0.139470238671613	0.47551391547096
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	6/5347	13/18639	0.461538461538462	1.60886766123347	0.139470238671613	0.47551391547096
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0004707	MAP kinase activity	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0004708	MAP kinase kinase activity	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0030275	LRR domain binding	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0031435	mitogen-activated protein kinase kinase kinase binding	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0034450	ubiquitin-ubiquitin ligase activity	7/5347	16/18639	0.4375	1.52507247054423	0.145766055617445	0.4884940498009
GO:0019213	deacetylase activity	14/5347	37/18639	0.378378378378378	1.31898159614636	0.147160598969479	0.489776293212406
GO:0042805	actinin binding	14/5347	37/18639	0.378378378378378	1.31898159614636	0.147160598969479	0.489776293212406
GO:0003924	GTPase activity	104/5347	331/18639	0.314199395770393	1.09526136857385	0.147514864606453	0.489776293212406
GO:0004222	metalloendopeptidase activity	37/5347	110/18639	0.336363636363636	1.17252325008076	0.148146827442102	0.489776293212406
GO:0008376	acetylgalactosaminyltransferase activity	13/5347	34/18639	0.382352941176471	1.33283644484538	0.148843598043164	0.489776293212406
GO:0046527	glucosyltransferase activity	8/5347	19/18639	0.421052631578947	1.46773891902001	0.149279902941387	0.489776293212406
GO:0120227	acyl-CoA binding	8/5347	19/18639	0.421052631578947	1.46773891902001	0.149279902941387	0.489776293212406
GO:1990380	K48-linked deubiquitinase activity	8/5347	19/18639	0.421052631578947	1.46773891902001	0.149279902941387	0.489776293212406
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	11/5347	28/18639	0.392857142857143	1.36945283069278	0.151153887464844	0.489776293212406
GO:0141052	histone H3 demethylase activity	11/5347	28/18639	0.392857142857143	1.36945283069278	0.151153887464844	0.489776293212406
GO:0003707	nuclear steroid receptor activity	10/5347	25/18639	0.4	1.39435197306901	0.151495578322615	0.489776293212406
GO:0004709	MAP kinase kinase kinase activity	10/5347	25/18639	0.4	1.39435197306901	0.151495578322615	0.489776293212406
GO:0008139	nuclear localization sequence binding	10/5347	25/18639	0.4	1.39435197306901	0.151495578322615	0.489776293212406
GO:0017056	structural constituent of nuclear pore	10/5347	25/18639	0.4	1.39435197306901	0.151495578322615	0.489776293212406
GO:0047617	fatty acyl-CoA hydrolase activity	10/5347	25/18639	0.4	1.39435197306901	0.151495578322615	0.489776293212406
GO:0003725	double-stranded RNA binding	26/5347	75/18639	0.346666666666667	1.20843837665981	0.154058893734637	0.496894178383549
GO:0019783	ubiquitin-like protein peptidase activity	42/5347	127/18639	0.330708661417323	1.15281068639564	0.159163913834969	0.512157418288635
GO:0005006	epidermal growth factor receptor activity	18/5347	50/18639	0.36	1.25491677576211	0.16122304054469	0.516611112699156
GO:0016279	protein-lysine N-methyltransferase activity	24/5347	69/18639	0.347826086956522	1.21247997658175	0.161299976235763	0.516611112699156
GO:0003689	DNA clamp loader activity	52/5347	160/18639	0.325	1.13291097811857	0.162619353470496	0.519625562019677
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	28/5347	82/18639	0.341463414634146	1.19030046481501	0.164950487037255	0.523386058764099
GO:0051087	protein-folding chaperone binding	44/5347	134/18639	0.328358208955224	1.14461729132531	0.165827940042982	0.523386058764099
GO:0016790	thiolester hydrolase activity	16/5347	44/18639	0.363636363636364	1.26759270279001	0.167843722519877	0.523386058764099
GO:0031072	heat shock protein binding	43/5347	131/18639	0.32824427480916	1.1442201305719	0.16975670523298	0.523386058764099
GO:0042169	SH2 domain binding	15/5347	41/18639	0.365853658536585	1.27532192658751	0.17114724508151	0.523386058764099
GO:0005516	calmodulin binding	66/5347	207/18639	0.318840579710145	1.11143997853327	0.171922804596115	0.523386058764099
GO:0098531	ligand-modulated transcription factor activity	21/5347	60/18639	0.35	1.22005797643538	0.172935184263878	0.523386058764099
GO:0000510	H3-H4 histone complex chaperone activity	49/5347	151/18639	0.324503311258278	1.13117958080102	0.174143939896943	0.523386058764099
GO:0140584	chromatin extrusion motor activity	49/5347	151/18639	0.324503311258278	1.13117958080102	0.174143939896943	0.523386058764099
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	49/5347	151/18639	0.324503311258278	1.13117958080102	0.174143939896943	0.523386058764099
GO:0140849	ATP-dependent H2AZ histone chaperone activity	49/5347	151/18639	0.324503311258278	1.13117958080102	0.174143939896943	0.523386058764099
GO:0017124	SH3 domain binding	38/5347	115/18639	0.330434782608696	1.15185597775266	0.174968289546971	0.523386058764099
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	30/5347	89/18639	0.337078651685393	1.17501570764242	0.174987260752874	0.523386058764099
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	30/5347	89/18639	0.337078651685393	1.17501570764242	0.174987260752874	0.523386058764099
GO:0061631	ubiquitin conjugating enzyme activity	13/5347	35/18639	0.371428571428571	1.29475540356408	0.177595714944631	0.523386058764099
GO:0140658	ATP-dependent chromatin remodeler activity	51/5347	158/18639	0.322784810126582	1.12518909219176	0.179803208575277	0.523386058764099
GO:0043425	bHLH transcription factor binding	12/5347	32/18639	0.375	1.3072049747522	0.180646344744801	0.523386058764099
GO:0071813	lipoprotein particle binding	12/5347	32/18639	0.375	1.3072049747522	0.180646344744801	0.523386058764099
GO:0071814	protein-lipid complex binding	12/5347	32/18639	0.375	1.3072049747522	0.180646344744801	0.523386058764099
GO:0140142	nucleocytoplasmic carrier activity	12/5347	32/18639	0.375	1.3072049747522	0.180646344744801	0.523386058764099
GO:0016278	lysine N-methyltransferase activity	24/5347	70/18639	0.342857142857143	1.19515883405915	0.181740617924421	0.523386058764099
GO:0005225	volume-sensitive anion channel activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0008046	axon guidance receptor activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0008172	S-methyltransferase activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0008432	JUN kinase binding	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0015217	ADP transmembrane transporter activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0035252	UDP-xylosyltransferase activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0042285	xylosyltransferase activity	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0042608	T cell receptor binding	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0050998	nitric-oxide synthase binding	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0140031	phosphorylation-dependent protein binding	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:1900750	oligopeptide binding	5/5347	11/18639	0.454545454545455	1.58449087848751	0.182272593769083	0.523386058764099
GO:0035250	UDP-galactosyltransferase activity	11/5347	29/18639	0.379310344827586	1.32223031928958	0.183484395395282	0.523386058764099
GO:0051861	glycolipid binding	11/5347	29/18639	0.379310344827586	1.32223031928958	0.183484395395282	0.523386058764099
GO:0099604	ligand-gated calcium channel activity	11/5347	29/18639	0.379310344827586	1.32223031928958	0.183484395395282	0.523386058764099
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	28/5347	83/18639	0.337349397590361	1.17595949535941	0.183826363303285	0.523386058764099
GO:0004386	helicase activity	50/5347	155/18639	0.32258064516129	1.1244773976363	0.183967170227284	0.523386058764099
GO:0008157	protein phosphatase 1 binding	10/5347	26/18639	0.384615384615385	1.34072305102789	0.185995567967558	0.523386058764099
GO:0016289	acyl-CoA hydrolase activity	10/5347	26/18639	0.384615384615385	1.34072305102789	0.185995567967558	0.523386058764099
GO:0043548	phosphatidylinositol 3-kinase binding	10/5347	26/18639	0.384615384615385	1.34072305102789	0.185995567967558	0.523386058764099
GO:0004065	arylsulfatase activity	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0005347	ATP transmembrane transporter activity	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0008174	mRNA methyltransferase activity	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0008191	metalloendopeptidase inhibitor activity	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0008331	high voltage-gated calcium channel activity	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0019992	diacylglycerol binding	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0030983	mismatched DNA binding	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0042043	neurexin family protein binding	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	6/5347	14/18639	0.428571428571429	1.49394854257394	0.187447213504348	0.523386058764099
GO:0016741	transferase activity, transferring one-carbon groups	68/5347	215/18639	0.316279069767442	1.10251086242666	0.187967749376216	0.523386058764099
GO:0008171	O-methyltransferase activity	9/5347	23/18639	0.391304347826087	1.36403997365447	0.188008846713757	0.523386058764099
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	9/5347	23/18639	0.391304347826087	1.36403997365447	0.188008846713757	0.523386058764099
GO:0008013	beta-catenin binding	35/5347	106/18639	0.330188679245283	1.15099809097678	0.188183390965066	0.523386058764099
GO:0015616	DNA translocase activity	49/5347	152/18639	0.322368421052632	1.1237376098747	0.18824995503714	0.523386058764099
GO:0140674	ATP-dependent histone chaperone activity	49/5347	152/18639	0.322368421052632	1.1237376098747	0.18824995503714	0.523386058764099
GO:0030742	GTP-dependent protein binding	8/5347	20/18639	0.4	1.39435197306901	0.189259339986603	0.523386058764099
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:0005092	GDP-dissociation inhibitor activity	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:0030169	low-density lipoprotein particle binding	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:0032183	SUMO binding	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:0038191	neuropilin binding	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:1901567	fatty acid derivative binding	7/5347	17/18639	0.411764705882353	1.4353623252181	0.189317955753826	0.523386058764099
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	17/5347	48/18639	0.354166666666667	1.23458247615485	0.189994566132454	0.524201875232915
GO:0030295	protein kinase activator activity	45/5347	139/18639	0.323741007194245	1.12852228036161	0.191122838553393	0.525205560344724
GO:0070851	growth factor receptor binding	45/5347	139/18639	0.323741007194245	1.12852228036161	0.191122838553393	0.525205560344724
GO:0140793	histone H2AXY142 phosphatase activity	30/5347	90/18639	0.333333333333333	1.16195997755751	0.193686446077471	0.530358147714535
GO:0004715	non-membrane spanning protein tyrosine kinase activity	16/5347	45/18639	0.355555555555556	1.23942397606134	0.194541853310135	0.530358147714535
GO:0042605	peptide antigen binding	16/5347	45/18639	0.355555555555556	1.23942397606134	0.194541853310135	0.530358147714535
GO:0141110	transporter inhibitor activity	16/5347	45/18639	0.355555555555556	1.23942397606134	0.194541853310135	0.530358147714535
GO:0004520	DNA endonuclease activity	15/5347	42/18639	0.357142857142857	1.24495711881162	0.199197991692523	0.541976317991143
GO:0019888	protein phosphatase regulator activity	35/5347	107/18639	0.327102803738318	1.14024109947232	0.205948402143475	0.558990324471068
GO:0033192	calmodulin-dependent protein phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0140791	histone H2AXS140 phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:1990439	MAP kinase serine/threonine phosphatase activity	27/5347	81/18639	0.333333333333333	1.16195997755751	0.209112828805043	0.558990324471068
GO:0019239	deaminase activity	12/5347	33/18639	0.363636363636364	1.26759270279001	0.213723299068245	0.568552753128978
GO:0005004	GPI-linked ephrin receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0005008	hepatocyte growth factor receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0005009	insulin receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0005011	macrophage colony-stimulating factor receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0005018	platelet-derived growth factor alpha-receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0005020	stem cell factor receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0008288	boss receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0036332	placental growth factor receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0038062	protein tyrosine kinase collagen receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0060175	brain-derived neurotrophic factor receptor activity	17/5347	49/18639	0.346938775510204	1.209386915417	0.21724177248378	0.568552753128978
GO:0001965	G-protein alpha-subunit binding	11/5347	30/18639	0.366666666666667	1.27815597531326	0.218681939742662	0.570149877052026
GO:0033612	receptor serine/threonine kinase binding	11/5347	30/18639	0.366666666666667	1.27815597531326	0.218681939742662	0.570149877052026
GO:0004683	calcium/calmodulin-dependent protein kinase activity	10/5347	27/18639	0.37037037037037	1.29106664173057	0.223630770516323	0.581948255093613
GO:0004879	nuclear receptor activity	20/5347	59/18639	0.338983050847458	1.18165421446526	0.22628075808242	0.586813942349697
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	9/5347	24/18639	0.375	1.3072049747522	0.228490144946934	0.586813942349697
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	9/5347	24/18639	0.375	1.3072049747522	0.228490144946934	0.586813942349697
GO:0030215	semaphorin receptor binding	9/5347	24/18639	0.375	1.3072049747522	0.228490144946934	0.586813942349697
GO:0048027	mRNA 5'-UTR binding	9/5347	24/18639	0.375	1.3072049747522	0.228490144946934	0.586813942349697
GO:0060229	lipase activator activity	9/5347	24/18639	0.375	1.3072049747522	0.228490144946934	0.586813942349697
GO:0070840	dynein complex binding	9/5347	24/18639	0.375	1.3072049747522	0.228490144946934	0.586813942349697
GO:0033549	MAP kinase phosphatase activity	27/5347	82/18639	0.329268292682927	1.14778973392876	0.230792523854684	0.591607931417885
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/5347	21/18639	0.380952380952381	1.32795426006572	0.233129078009423	0.591607931417885
GO:0008373	sialyltransferase activity	8/5347	21/18639	0.380952380952381	1.32795426006572	0.233129078009423	0.591607931417885
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	8/5347	21/18639	0.380952380952381	1.32795426006572	0.233129078009423	0.591607931417885
GO:0004706	JUN kinase kinase kinase activity	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0015172	acidic amino acid transmembrane transporter activity	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0017075	syntaxin-1 binding	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0031690	adrenergic receptor binding	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0034185	apolipoprotein binding	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0050811	GABA receptor binding	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:1990381	ubiquitin-specific protease binding	7/5347	18/18639	0.388888888888889	1.35561997381709	0.237324505872425	0.591607931417885
GO:0008235	metalloexopeptidase activity	22/5347	66/18639	0.333333333333333	1.16195997755751	0.239087806864531	0.591607931417885
GO:0005003	ephrin receptor activity	18/5347	53/18639	0.339622641509434	1.18388375071897	0.239194232394056	0.591607931417885
GO:0005005	transmembrane-ephrin receptor activity	18/5347	53/18639	0.339622641509434	1.18388375071897	0.239194232394056	0.591607931417885
GO:0005246	calcium channel regulator activity	18/5347	53/18639	0.339622641509434	1.18388375071897	0.239194232394056	0.591607931417885
GO:0016251	RNA polymerase II general transcription initiation factor activity	18/5347	53/18639	0.339622641509434	1.18388375071897	0.239194232394056	0.591607931417885
GO:0038064	collagen receptor activity	18/5347	53/18639	0.339622641509434	1.18388375071897	0.239194232394056	0.591607931417885
GO:0000774	adenyl-nucleotide exchange factor activity	6/5347	15/18639	0.4	1.39435197306901	0.240676540105348	0.591607931417885
GO:0008252	nucleotidase activity	6/5347	15/18639	0.4	1.39435197306901	0.240676540105348	0.591607931417885
GO:0015929	hexosaminidase activity	6/5347	15/18639	0.4	1.39435197306901	0.240676540105348	0.591607931417885
GO:0061578	K63-linked deubiquitinase activity	6/5347	15/18639	0.4	1.39435197306901	0.240676540105348	0.591607931417885
GO:0140776	protein-containing complex destabilizing activity	6/5347	15/18639	0.4	1.39435197306901	0.240676540105348	0.591607931417885
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/5347	12/18639	0.416666666666667	1.45244997194689	0.242412856905582	0.591607931417885
GO:0005049	nuclear export signal receptor activity	5/5347	12/18639	0.416666666666667	1.45244997194689	0.242412856905582	0.591607931417885
GO:0016423	tRNA (guanine) methyltransferase activity	5/5347	12/18639	0.416666666666667	1.45244997194689	0.242412856905582	0.591607931417885
GO:0043047	single-stranded telomeric DNA binding	5/5347	12/18639	0.416666666666667	1.45244997194689	0.242412856905582	0.591607931417885
GO:0070410	co-SMAD binding	5/5347	12/18639	0.416666666666667	1.45244997194689	0.242412856905582	0.591607931417885
GO:0017022	myosin binding	25/5347	76/18639	0.328947368421053	1.14667103048438	0.243586872520124	0.593419083054344
GO:0005007	fibroblast growth factor receptor activity	17/5347	50/18639	0.34	1.18519917710866	0.246099907119069	0.595319141516903
GO:0005017	platelet-derived growth factor receptor activity	17/5347	50/18639	0.34	1.18519917710866	0.246099907119069	0.595319141516903
GO:0005019	platelet-derived growth factor beta-receptor activity	17/5347	50/18639	0.34	1.18519917710866	0.246099907119069	0.595319141516903
GO:0032813	tumor necrosis factor receptor superfamily binding	17/5347	50/18639	0.34	1.18519917710866	0.246099907119069	0.595319141516903
GO:0052866	phosphatidylinositol phosphate phosphatase activity	12/5347	34/18639	0.352941176470588	1.23031056447266	0.249112226900107	0.601546924008343
GO:0043539	protein serine/threonine kinase activator activity	24/5347	73/18639	0.328767123287671	1.14604271759097	0.250387301747332	0.603565180001465
GO:0043495	protein-membrane adaptor activity	16/5347	47/18639	0.340425531914894	1.1866825302715	0.253341382024094	0.607239320667249
GO:1990518	single-stranded 3'-5' DNA helicase activity	16/5347	47/18639	0.340425531914894	1.1866825302715	0.253341382024094	0.607239320667249
GO:0001540	amyloid-beta binding	27/5347	83/18639	0.325301204819277	1.13396094195371	0.253436922691966	0.607239320667249
GO:0033218	amide binding	76/5347	247/18639	0.307692307692308	1.07257844082232	0.253679308633916	0.607239320667249
GO:0016411	acylglycerol O-acyltransferase activity	11/5347	31/18639	0.354838709677419	1.23692513739993	0.256339283457218	0.612539435600378
GO:0016504	peptidase activator activity	19/5347	57/18639	0.333333333333333	1.16195997755751	0.260378670328232	0.62111161984547
GO:0016248	channel inhibitor activity	15/5347	44/18639	0.340909090909091	1.18836815886563	0.260951701147945	0.62139971815819
GO:0051393	alpha-actinin binding	10/5347	28/18639	0.357142857142857	1.24495711881162	0.263895705544922	0.627323009374953
GO:0008173	RNA methyltransferase activity	22/5347	67/18639	0.328358208955224	1.14461729132531	0.264898563815751	0.627535563246279
GO:0016500	protein-hormone receptor activity	22/5347	67/18639	0.328358208955224	1.14461729132531	0.264898563815751	0.627535563246279
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	18/5347	54/18639	0.333333333333333	1.16195997755751	0.268172111283994	0.633901425364731
GO:0016877	ligase activity, forming carbon-sulfur bonds	14/5347	41/18639	0.341463414634146	1.19030046481501	0.268969818768296	0.633901425364731
GO:0061650	ubiquitin-like protein conjugating enzyme activity	14/5347	41/18639	0.341463414634146	1.19030046481501	0.268969818768296	0.633901425364731
GO:0015662	P-type ion transporter activity	9/5347	25/18639	0.36	1.25491677576211	0.271799588673114	0.636976658414139
GO:0120020	cholesterol transfer activity	9/5347	25/18639	0.36	1.25491677576211	0.271799588673114	0.636976658414139
GO:0140358	P-type transmembrane transporter activity	9/5347	25/18639	0.36	1.25491677576211	0.271799588673114	0.636976658414139
GO:0140713	histone chaperone activity	51/5347	164/18639	0.310975609756098	1.08402363759938	0.272129038201674	0.636976658414139
GO:0004536	DNA nuclease activity	21/5347	64/18639	0.328125	1.14380435290817	0.272659117722842	0.637132019985008
GO:0017018	myosin phosphatase activity	27/5347	84/18639	0.321428571428571	1.12046140693046	0.276956874464176	0.644980924599623
GO:0051117	ATPase binding	27/5347	84/18639	0.321428571428571	1.12046140693046	0.276956874464176	0.644980924599623
GO:0042562	hormone binding	30/5347	94/18639	0.319148936170213	1.11251487212953	0.277685573508404	0.645583719121061
GO:0008093	cytoskeletal anchor activity	8/5347	22/18639	0.363636363636364	1.26759270279001	0.280063194284401	0.649516145048294
GO:0015631	tubulin binding	116/5347	385/18639	0.301298701298701	1.05029109659744	0.280751183338871	0.649516145048294
GO:0015026	coreceptor activity	20/5347	61/18639	0.327868852459016	1.14291145333525	0.280795189344022	0.649516145048294
GO:1902936	phosphatidylinositol bisphosphate binding	35/5347	111/18639	0.315315315315315	1.09915133012197	0.284609633696159	0.657064297682321
GO:0043138	3'-5' DNA helicase activity	16/5347	48/18639	0.333333333333333	1.16195997755751	0.285014789969915	0.657064297682321
GO:0005154	epidermal growth factor receptor binding	12/5347	35/18639	0.342857142857143	1.19515883405915	0.286425189659486	0.659209732985148
GO:0003756	protein disulfide isomerase activity	7/5347	19/18639	0.368421052631579	1.28427155414251	0.288683857582198	0.661086033863233
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	7/5347	19/18639	0.368421052631579	1.28427155414251	0.288683857582198	0.661086033863233
GO:0097001	ceramide binding	7/5347	19/18639	0.368421052631579	1.28427155414251	0.288683857582198	0.661086033863233
GO:0031490	chromatin DNA binding	40/5347	128/18639	0.3125	1.08933747896016	0.28956284009203	0.661995577847669
GO:0015297	antiporter activity	42/5347	135/18639	0.311111111111111	1.08449597905368	0.294988947198553	0.672588436704896
GO:0000062	fatty-acyl-CoA binding	6/5347	16/18639	0.375	1.3072049747522	0.297622830798091	0.672588436704896
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	6/5347	16/18639	0.375	1.3072049747522	0.297622830798091	0.672588436704896
GO:0008142	oxysterol binding	6/5347	16/18639	0.375	1.3072049747522	0.297622830798091	0.672588436704896
GO:0019841	retinol binding	6/5347	16/18639	0.375	1.3072049747522	0.297622830798091	0.672588436704896
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	6/5347	16/18639	0.375	1.3072049747522	0.297622830798091	0.672588436704896
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	6/5347	16/18639	0.375	1.3072049747522	0.297622830798091	0.672588436704896
GO:0008374	O-acyltransferase activity	18/5347	55/18639	0.327272727272727	1.14083343251101	0.298337474485225	0.673096371006074
GO:0008307	structural constituent of muscle	14/5347	42/18639	0.333333333333333	1.16195997755751	0.303855732306182	0.676528473188907
GO:0019894	kinesin binding	14/5347	42/18639	0.333333333333333	1.16195997755751	0.303855732306182	0.676528473188907
GO:0035198	miRNA binding	14/5347	42/18639	0.333333333333333	1.16195997755751	0.303855732306182	0.676528473188907
GO:0051879	Hsp90 protein binding	14/5347	42/18639	0.333333333333333	1.16195997755751	0.303855732306182	0.676528473188907
GO:0008094	ATP-dependent activity, acting on DNA	64/5347	210/18639	0.304761904761905	1.06236340805258	0.305872722240498	0.676528473188907
GO:0004535	poly(A)-specific ribonuclease activity	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0008035	high-density lipoprotein particle binding	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0008253	5'-nucleotidase activity	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0008417	fucosyltransferase activity	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0035673	oligopeptide transmembrane transporter activity	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0043560	insulin receptor substrate binding	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0045159	myosin II binding	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0089720	caspase binding	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0140852	histone ubiquitin ligase activity	5/5347	13/18639	0.384615384615385	1.34072305102789	0.306751993301812	0.676528473188907
GO:0015179	L-amino acid transmembrane transporter activity	20/5347	62/18639	0.32258064516129	1.1244773976363	0.309637172678222	0.678833527702233
GO:0001094	TFIID-class transcription factor complex binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0004090	carbonyl reductase (NADPH) activity	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0004382	GDP phosphatase activity	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0008190	eukaryotic initiation factor 4E binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0015279	store-operated calcium channel activity	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0015643	toxic substance binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0016783	sulfurtransferase activity	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0019911	structural constituent of myelin sheath	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0031434	mitogen-activated protein kinase kinase binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0043208	glycosphingolipid binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0098505	G-rich strand telomeric DNA binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:1990763	arrestin family protein binding	4/5347	10/18639	0.4	1.39435197306901	0.315702055459772	0.678833527702233
GO:0004112	cyclic-nucleotide phosphodiesterase activity	9/5347	26/18639	0.346153846153846	1.20665074592511	0.317225246693703	0.679980481992431
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/5347	26/18639	0.346153846153846	1.20665074592511	0.317225246693703	0.679980481992431
GO:0035254	glutamate receptor binding	16/5347	49/18639	0.326530612244898	1.13824650862776	0.317874434811677	0.680310706279196
GO:0045309	protein phosphorylated amino acid binding	19/5347	59/18639	0.322033898305085	1.122571503742	0.319295093813325	0.682288427526452
GO:0030276	clathrin binding	15/5347	46/18639	0.326086956521739	1.13669997804539	0.32853532951463	0.697938664886629
GO:0003887	DNA-directed DNA polymerase activity	8/5347	23/18639	0.347826086956522	1.21247997658175	0.329158846322078	0.697938664886629
GO:0043274	phospholipase binding	8/5347	23/18639	0.347826086956522	1.21247997658175	0.329158846322078	0.697938664886629
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	8/5347	23/18639	0.347826086956522	1.21247997658175	0.329158846322078	0.697938664886629
GO:0140103	catalytic activity, acting on a glycoprotein	8/5347	23/18639	0.347826086956522	1.21247997658175	0.329158846322078	0.697938664886629
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	55/5347	181/18639	0.303867403314917	1.05924528340878	0.331887694726944	0.702640512411126
GO:0008200	ion channel inhibitor activity	14/5347	43/18639	0.325581395348837	1.13493765249803	0.339891436620734	0.718478206025981
GO:0015095	magnesium ion transmembrane transporter activity	7/5347	20/18639	0.35	1.22005797643538	0.342220136287518	0.720077285235911
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	7/5347	20/18639	0.35	1.22005797643538	0.342220136287518	0.720077285235911
GO:0061608	nuclear import signal receptor activity	7/5347	20/18639	0.35	1.22005797643538	0.342220136287518	0.720077285235911
GO:0061791	GTPase motor activity	13/5347	40/18639	0.325	1.13291097811857	0.352038536517173	0.738474731564269
GO:1990606	membrane scission GTPase motor activity	13/5347	40/18639	0.325	1.13291097811857	0.352038536517173	0.738474731564269
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	6/5347	17/18639	0.352941176470588	1.23031056447266	0.356698217185872	0.745971614023421
GO:0019198	transmembrane receptor protein phosphatase activity	6/5347	17/18639	0.352941176470588	1.23031056447266	0.356698217185872	0.745971614023421
GO:0004527	exonuclease activity	26/5347	84/18639	0.30952380952381	1.0789628363034	0.361683206639344	0.755247303833523
GO:0061749	forked DNA-dependent helicase activity	15/5347	47/18639	0.319148936170213	1.11251487212953	0.363782492400818	0.75782862741062
GO:0035255	ionotropic glutamate receptor binding	9/5347	27/18639	0.333333333333333	1.16195997755751	0.364022484782394	0.75782862741062
GO:0003684	damaged DNA binding	23/5347	74/18639	0.310810810810811	1.08344916826308	0.365660584552428	0.76008720601367
GO:0072341	modified amino acid binding	28/5347	91/18639	0.307692307692308	1.07257844082232	0.367520137225458	0.762798592972477
GO:0004705	JUN kinase activity	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0005313	L-glutamate transmembrane transporter activity	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0016530	metallochaperone activity	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0032454	histone H3K9 demethylase activity	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0070742	C2H2 zinc finger domain binding	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0098847	sequence-specific single stranded DNA binding	5/5347	14/18639	0.357142857142857	1.24495711881162	0.373032426522625	0.763377050165225
GO:0003925	G protein activity	17/5347	54/18639	0.314814814814815	1.09740664547098	0.373354714491289	0.763377050165225
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	17/5347	54/18639	0.314814814814815	1.09740664547098	0.373354714491289	0.763377050165225
GO:0042625	ATPase-coupled ion transmembrane transporter activity	8/5347	24/18639	0.333333333333333	1.16195997755751	0.379493197009651	0.772479485468533
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	8/5347	24/18639	0.333333333333333	1.16195997755751	0.379493197009651	0.772479485468533
GO:0046961	proton-transporting ATPase activity, rotational mechanism	8/5347	24/18639	0.333333333333333	1.16195997755751	0.379493197009651	0.772479485468533
GO:0043021	ribonucleoprotein complex binding	53/5347	177/18639	0.299435028248588	1.04379455611098	0.382707297929442	0.777869567093274
GO:0030544	Hsp70 protein binding	16/5347	51/18639	0.313725490196078	1.09360939064236	0.386064699130573	0.780486685479115
GO:0000099	sulfur amino acid transmembrane transporter activity	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0002162	dystroglycan binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0004016	adenylate cyclase activity	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0019107	myristoyltransferase activity	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0019215	intermediate filament binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0032050	clathrin heavy chain binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0032404	mismatch repair complex binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0043522	leucine zipper domain binding	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0140537	transcription regulator activator activity	4/5347	11/18639	0.363636363636364	1.26759270279001	0.391947462140167	0.780486685479115
GO:0017116	single-stranded DNA helicase activity	18/5347	58/18639	0.310344827586207	1.08182480669147	0.39378324328969	0.782324464196265
GO:0016878	acid-thiol ligase activity	10/5347	31/18639	0.32258064516129	1.1244773976363	0.394578496133924	0.782324464196265
GO:0070273	phosphatidylinositol-4-phosphate binding	10/5347	31/18639	0.32258064516129	1.1244773976363	0.394578496133924	0.782324464196265
GO:0004175	endopeptidase activity	119/5347	405/18639	0.293827160493827	1.02424620243958	0.395752093977117	0.783520716317808
GO:0009378	four-way junction helicase activity	15/5347	48/18639	0.3125	1.08933747896016	0.399585993505775	0.788837866489848
GO:0036121	double-stranded DNA helicase activity	15/5347	48/18639	0.3125	1.08933747896016	0.399585993505775	0.788837866489848
GO:0016798	hydrolase activity, acting on glycosyl bonds	39/5347	130/18639	0.3	1.04576397980176	0.402234589716214	0.792927297374574
GO:0005126	cytokine receptor binding	81/5347	275/18639	0.294545454545455	1.02675008925991	0.410965867648061	0.807619454118779
GO:0050698	proteoglycan sulfotransferase activity	9/5347	28/18639	0.321428571428571	1.12046140693046	0.411450959158039	0.807619454118779
GO:0097718	disordered domain specific binding	9/5347	28/18639	0.321428571428571	1.12046140693046	0.411450959158039	0.807619454118779
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	26/5347	86/18639	0.302325581395349	1.0538706773196	0.41521970055044	0.812660639326316
GO:0000400	four-way junction DNA binding	6/5347	18/18639	0.333333333333333	1.16195997755751	0.416385072842596	0.812660639326316
GO:0008308	voltage-gated monoatomic anion channel activity	6/5347	18/18639	0.333333333333333	1.16195997755751	0.416385072842596	0.812660639326316
GO:0016854	racemase and epimerase activity	6/5347	18/18639	0.333333333333333	1.16195997755751	0.416385072842596	0.812660639326316
GO:0001786	phosphatidylserine binding	18/5347	59/18639	0.305084745762712	1.06348879301874	0.426485357693947	0.830015412849126
GO:0070888	E-box binding	18/5347	59/18639	0.305084745762712	1.06348879301874	0.426485357693947	0.830015412849126
GO:0003697	single-stranded DNA binding	36/5347	121/18639	0.297520661157025	1.03712130228274	0.431437386442203	0.838465302647224
GO:0005402	carbohydrate:monoatomic cation symporter activity	5/5347	15/18639	0.333333333333333	1.16195997755751	0.439210369731263	0.849121127101649
GO:0048531	beta-1,3-galactosyltransferase activity	5/5347	15/18639	0.333333333333333	1.16195997755751	0.439210369731263	0.849121127101649
GO:0031369	translation initiation factor binding	10/5347	32/18639	0.3125	1.08933747896016	0.439392373631203	0.849121127101649
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	10/5347	32/18639	0.3125	1.08933747896016	0.439392373631203	0.849121127101649
GO:0008081	phosphoric diester hydrolase activity	26/5347	87/18639	0.298850574712644	1.04175722125846	0.442274125884859	0.853489675513758
GO:0005507	copper ion binding	19/5347	63/18639	0.301587301587302	1.05129712255203	0.444906025761908	0.85617329364184
GO:0141108	transporter regulator activity	50/5347	170/18639	0.294117647058824	1.02525880372721	0.445782784980701	0.85617329364184
GO:0016776	phosphotransferase activity, phosphate group as acceptor	12/5347	39/18639	0.307692307692308	1.07257844082232	0.446157262188907	0.85617329364184
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/5347	39/18639	0.307692307692308	1.07257844082232	0.446157262188907	0.85617329364184
GO:0031683	G-protein beta/gamma-subunit complex binding	7/5347	22/18639	0.318181818181818	1.10914361494126	0.451226818626243	0.864421173547118
GO:0003724	RNA helicase activity	23/5347	77/18639	0.298701298701299	1.04123686300608	0.451719305091462	0.864421173547118
GO:0101005	deubiquitinase activity	34/5347	115/18639	0.295652173913043	1.03060798009449	0.452342666506825	0.864421173547118
GO:0016860	intramolecular oxidoreductase activity	16/5347	53/18639	0.30188679245283	1.0523411117502	0.455686991437856	0.865261799512596
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	9/5347	29/18639	0.310344827586207	1.08182480669147	0.458806039301132	0.865261799512596
GO:0004518	nuclease activity	61/5347	209/18639	0.291866028708134	1.01740993250251	0.462462305806756	0.865261799512596
GO:0004190	aspartic-type endopeptidase activity	11/5347	36/18639	0.305555555555556	1.06512997942772	0.464199047857742	0.865261799512596
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/5347	36/18639	0.305555555555556	1.06512997942772	0.464199047857742	0.865261799512596
GO:0004000	adenosine deaminase activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0004126	cytidine deaminase activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0005095	GTPase inhibitor activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0008179	adenylate cyclase binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0008504	monoamine transmembrane transporter activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0016801	hydrolase activity, acting on ether bonds	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0016803	ether hydrolase activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0017166	vinculin binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0035197	siRNA binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0035259	nuclear glucocorticoid receptor binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0045295	gamma-catenin binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0070008	serine-type exopeptidase activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0070679	inositol 1,4,5 trisphosphate binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:1990459	transferrin receptor binding	4/5347	12/18639	0.333333333333333	1.16195997755751	0.466714764757459	0.865261799512596
GO:0015101	organic cation transmembrane transporter activity	24/5347	81/18639	0.296296296296296	1.03285331338445	0.46726656130884	0.865261799512596
GO:0015085	calcium ion transmembrane transporter activity	43/5347	147/18639	0.292517006802721	1.01967916397904	0.470843132651194	0.87071125741957
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	6/5347	19/18639	0.315789473684211	1.10080418926501	0.475324095270471	0.873122068050303
GO:0016918	retinal binding	6/5347	19/18639	0.315789473684211	1.10080418926501	0.475324095270471	0.873122068050303
GO:0030506	ankyrin binding	6/5347	19/18639	0.315789473684211	1.10080418926501	0.475324095270471	0.873122068050303
GO:0043395	heparan sulfate proteoglycan binding	6/5347	19/18639	0.315789473684211	1.10080418926501	0.475324095270471	0.873122068050303
GO:0070003	threonine-type peptidase activity	6/5347	19/18639	0.315789473684211	1.10080418926501	0.475324095270471	0.873122068050303
GO:0005112	Notch binding	8/5347	26/18639	0.307692307692308	1.07257844082232	0.480371340071639	0.880040295011243
GO:0030247	polysaccharide binding	8/5347	26/18639	0.307692307692308	1.07257844082232	0.480371340071639	0.880040295011243
GO:0004532	RNA exonuclease activity	12/5347	40/18639	0.3	1.04576397980176	0.486493858905364	0.888886385819109
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	12/5347	40/18639	0.3	1.04576397980176	0.486493858905364	0.888886385819109
GO:0050661	NADP binding	16/5347	54/18639	0.296296296296296	1.03285331338445	0.490353213310094	0.893561425846246
GO:0051287	NAD binding	16/5347	54/18639	0.296296296296296	1.03285331338445	0.490353213310094	0.893561425846246
GO:0008083	growth factor activity	47/5347	162/18639	0.290123456790123	1.01133553602228	0.493261010555695	0.897669706627185
GO:0005525	GTP binding	109/5347	378/18639	0.288359788359788	1.00518759963308	0.494006457262137	0.897837132643091
GO:0004896	cytokine receptor activity	28/5347	96/18639	0.291666666666667	1.01671498036282	0.497194865017645	0.902438235844444
GO:0005262	calcium channel activity	38/5347	131/18639	0.290076335877863	1.01117127817982	0.500757186163091	0.907704978612252
GO:0005212	structural constituent of eye lens	7/5347	23/18639	0.304347826086957	1.06091997950903	0.504631556509315	0.910195839449377
GO:0016849	phosphorus-oxygen lyase activity	7/5347	23/18639	0.304347826086957	1.06091997950903	0.504631556509315	0.910195839449377
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	9/5347	30/18639	0.3	1.04576397980176	0.505443541120724	0.910195839449377
GO:0031624	ubiquitin conjugating enzyme binding	9/5347	30/18639	0.3	1.04576397980176	0.505443541120724	0.910195839449377
GO:0051721	protein phosphatase 2A binding	9/5347	30/18639	0.3	1.04576397980176	0.505443541120724	0.910195839449377
GO:0070001	aspartic-type peptidase activity	11/5347	37/18639	0.297297297297297	1.03634268268643	0.506127575772597	0.910234671611974
GO:0016830	carbon-carbon lyase activity	15/5347	51/18639	0.294117647058824	1.02525880372721	0.507280196291081	0.910833959883929
GO:0061980	regulatory RNA binding	17/5347	58/18639	0.293103448275862	1.02172342854195	0.50778661810123	0.910833959883929
GO:0008186	ATP-dependent activity, acting on RNA	23/5347	79/18639	0.291139240506329	1.01487643609453	0.50912978246915	0.912052569899102
GO:0045296	cadherin binding	96/5347	334/18639	0.287425149700599	1.00192956148671	0.512003346966143	0.916005987931616
GO:0099106	ion channel regulator activity	46/5347	160/18639	0.2875	1.00219048064335	0.523060252720012	0.934017985781692
GO:0098631	cell adhesion mediator activity	22/5347	76/18639	0.289473684210526	1.00907050682626	0.523430748946072	0.934017985781692
GO:0098632	cell-cell adhesion mediator activity	16/5347	55/18639	0.290909090909091	1.01407416223201	0.524584251096993	0.934862206235109
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	10/5347	34/18639	0.294117647058824	1.02525880372721	0.527461566854552	0.936565296847059
GO:0016831	carboxy-lyase activity	10/5347	34/18639	0.294117647058824	1.02525880372721	0.527461566854552	0.936565296847059
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	8/5347	27/18639	0.296296296296296	1.03285331338445	0.529360331772374	0.936565296847059
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	8/5347	27/18639	0.296296296296296	1.03285331338445	0.529360331772374	0.936565296847059
GO:0001972	retinoic acid binding	6/5347	20/18639	0.3	1.04576397980176	0.532368649120308	0.936565296847059
GO:0005326	neurotransmitter transmembrane transporter activity	6/5347	20/18639	0.3	1.04576397980176	0.532368649120308	0.936565296847059
GO:0016505	peptidase activator activity involved in apoptotic process	6/5347	20/18639	0.3	1.04576397980176	0.532368649120308	0.936565296847059
GO:0140939	histone H4 methyltransferase activity	6/5347	20/18639	0.3	1.04576397980176	0.532368649120308	0.936565296847059
GO:0008017	microtubule binding	79/5347	276/18639	0.286231884057971	0.99776998072873	0.53247462182868	0.936565296847059
GO:0004843	cysteine-type deubiquitinase activity	31/5347	108/18639	0.287037037037037	1.00057664734119	0.535008629881556	0.936565296847059
GO:0005172	vascular endothelial growth factor receptor binding	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0009982	pseudouridine synthase activity	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0019104	DNA N-glycosylase activity	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0030955	potassium ion binding	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0031432	titin binding	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0061459	L-arginine transmembrane transporter activity	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0097157	pre-mRNA intronic binding	4/5347	13/18639	0.307692307692308	1.07257844082232	0.537809329848857	0.936565296847059
GO:0016247	channel regulator activity	48/5347	168/18639	0.285714285714286	0.995965695049293	0.542641690502493	0.943784408544841
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	11/5347	38/18639	0.289473684210526	1.00907050682626	0.547103421656917	0.950341468213152
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	26/5347	91/18639	0.285714285714286	0.995965695049293	0.549480509574378	0.953143147887795
GO:0005164	tumor necrosis factor receptor binding	9/5347	31/18639	0.290322580645161	1.01202965787267	0.550797423160778	0.953143147887795
GO:0008327	methyl-CpG binding	9/5347	31/18639	0.290322580645161	1.01202965787267	0.550797423160778	0.953143147887795
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	37/5347	130/18639	0.284615384615385	0.992135057760642	0.556017421441631	0.95879877766716
GO:0004622	lysophospholipase activity	7/5347	24/18639	0.291666666666667	1.01671498036282	0.556159116303294	0.95879877766716
GO:0030552	cAMP binding	7/5347	24/18639	0.291666666666667	1.01671498036282	0.556159116303294	0.95879877766716
GO:0004659	prenyltransferase activity	5/5347	17/18639	0.294117647058824	1.02525880372721	0.56476422730184	0.959145883839038
GO:0016018	cyclosporin A binding	5/5347	17/18639	0.294117647058824	1.02525880372721	0.56476422730184	0.959145883839038
GO:0017110	nucleoside diphosphate phosphatase activity	5/5347	17/18639	0.294117647058824	1.02525880372721	0.56476422730184	0.959145883839038
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/5347	17/18639	0.294117647058824	1.02525880372721	0.56476422730184	0.959145883839038
GO:0031489	myosin V binding	5/5347	17/18639	0.294117647058824	1.02525880372721	0.56476422730184	0.959145883839038
GO:0051787	misfolded protein binding	5/5347	17/18639	0.294117647058824	1.02525880372721	0.56476422730184	0.959145883839038
GO:0042056	chemoattractant activity	12/5347	42/18639	0.285714285714286	0.995965695049293	0.564842430527604	0.959145883839038
GO:0031491	nucleosome binding	21/5347	74/18639	0.283783783783784	0.989236197109771	0.567373025315423	0.959145883839038
GO:0048029	monosaccharide binding	21/5347	74/18639	0.283783783783784	0.989236197109771	0.567373025315423	0.959145883839038
GO:0016229	steroid dehydrogenase activity	10/5347	35/18639	0.285714285714286	0.995965695049293	0.569750994044745	0.959145883839038
GO:0034061	DNA polymerase activity	10/5347	35/18639	0.285714285714286	0.995965695049293	0.569750994044745	0.959145883839038
GO:0043015	gamma-tubulin binding	10/5347	35/18639	0.285714285714286	0.995965695049293	0.569750994044745	0.959145883839038
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	19/5347	67/18639	0.283582089552239	0.988533115235493	0.569894938845016	0.959145883839038
GO:0016866	intramolecular transferase activity	8/5347	28/18639	0.285714285714286	0.995965695049293	0.576524080818107	0.959145883839038
GO:0046625	sphingolipid binding	8/5347	28/18639	0.285714285714286	0.995965695049293	0.576524080818107	0.959145883839038
GO:0051959	dynein light intermediate chain binding	8/5347	28/18639	0.285714285714286	0.995965695049293	0.576524080818107	0.959145883839038
GO:0008146	sulfotransferase activity	15/5347	53/18639	0.283018867924528	0.986569792265809	0.576524650799713	0.959145883839038
GO:0017046	peptide hormone binding	15/5347	53/18639	0.283018867924528	0.986569792265809	0.576524650799713	0.959145883839038
GO:0004180	carboxypeptidase activity	13/5347	46/18639	0.282608695652174	0.985139980972671	0.581021723352145	0.959145883839038
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0005031	tumor necrosis factor receptor activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0005528	FK506 binding	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0016427	tRNA (cytidine) methyltransferase activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0030957	Tat protein binding	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0032052	bile acid binding	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0035256	G protein-coupled glutamate receptor binding	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0047429	nucleoside triphosphate diphosphatase activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0051864	histone H3K36 demethylase activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0097177	mitochondrial ribosome binding	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0141109	transporter activator activity	3/5347	10/18639	0.3	1.04576397980176	0.581490917931527	0.959145883839038
GO:0009975	cyclase activity	6/5347	21/18639	0.285714285714286	0.995965695049293	0.586609842597804	0.963213137574006
GO:0015174	basic amino acid transmembrane transporter activity	6/5347	21/18639	0.285714285714286	0.995965695049293	0.586609842597804	0.963213137574006
GO:0035613	RNA stem-loop binding	6/5347	21/18639	0.285714285714286	0.995965695049293	0.586609842597804	0.963213137574006
GO:0000217	DNA secondary structure binding	11/5347	39/18639	0.282051282051282	0.983196904087123	0.586760841447921	0.963213137574006
GO:0016887	ATP hydrolysis activity	118/5347	417/18639	0.282973621103118	0.986412067279036	0.589261895241243	0.966164491720129
GO:0070717	poly-purine tract binding	9/5347	32/18639	0.28125	0.980403731064148	0.594390703411482	0.97341218890033
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	12/5347	43/18639	0.27906976744186	0.97280370214117	0.60220511072415	0.97589577091815
GO:0008474	palmitoyl-(protein) hydrolase activity	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0008494	translation activator activity	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0015386	potassium:proton antiporter activity	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0032036	myosin heavy chain binding	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0044548	S100 protein binding	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0071933	Arp2/3 complex binding	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0098599	palmitoyl hydrolase activity	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:1901612	cardiolipin binding	4/5347	14/18639	0.285714285714286	0.995965695049293	0.60372009117935	0.97589577091815
GO:0008483	transaminase activity	7/5347	25/18639	0.28	0.976046381148307	0.605153895156554	0.977063985834436
GO:0017069	snRNA binding	15/5347	54/18639	0.277777777777778	0.968299981297924	0.609667511372644	0.983196197917856
GO:0001784	phosphotyrosine residue binding	13/5347	47/18639	0.276595744680851	0.964179555845592	0.616358944646643	0.992822028070911
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/5347	18/18639	0.277777777777778	0.968299981297924	0.621833132863088	0.99929675386419
GO:1901611	phosphatidylglycerol binding	5/5347	18/18639	0.277777777777778	0.968299981297924	0.621833132863088	0.99929675386419
GO:0016597	amino acid binding	14/5347	51/18639	0.274509803921569	0.956908216812066	0.629428824442142	1
GO:0042626	ATPase-coupled transmembrane transporter activity	27/5347	98/18639	0.275510204081633	0.960395491654676	0.635768059927683	1
GO:0061133	endopeptidase activator activity	6/5347	22/18639	0.272727272727273	0.950694527092507	0.637378476587139	1
GO:0140517	protein-RNA adaptor activity	6/5347	22/18639	0.272727272727273	0.950694527092507	0.637378476587139	1
GO:0140784	metal ion sensor activity	6/5347	22/18639	0.272727272727273	0.950694527092507	0.637378476587139	1
GO:0004519	endonuclease activity	35/5347	127/18639	0.275590551181102	0.960675571996366	0.643690889706759	1
GO:0008143	poly(A) binding	7/5347	26/18639	0.269230769230769	0.938506135719526	0.651126415450997	1
GO:0008198	ferrous iron binding	7/5347	26/18639	0.269230769230769	0.938506135719526	0.651126415450997	1
GO:0030507	spectrin binding	7/5347	26/18639	0.269230769230769	0.938506135719526	0.651126415450997	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0008526	phosphatidylinositol transfer activity	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0034056	estrogen response element binding	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0045294	alpha-catenin binding	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0070697	activin receptor binding	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0070990	snRNP binding	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	3/5347	11/18639	0.272727272727273	0.950694527092507	0.652569713853288	1
GO:0016782	transferase activity, transferring sulphur-containing groups	19/5347	70/18639	0.271428571428571	0.946167410296829	0.656345378070499	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	11/5347	41/18639	0.268292682926829	0.935236079497507	0.660954404326733	1
GO:0017080	sodium channel regulator activity	11/5347	41/18639	0.268292682926829	0.935236079497507	0.660954404326733	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/5347	30/18639	0.266666666666667	0.929567982046007	0.663523779158441	1
GO:0016769	transferase activity, transferring nitrogenous groups	8/5347	30/18639	0.266666666666667	0.929567982046007	0.663523779158441	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/5347	15/18639	0.266666666666667	0.929567982046007	0.663541808069564	1
GO:0033130	acetylcholine receptor binding	4/5347	15/18639	0.266666666666667	0.929567982046007	0.663541808069564	1
GO:0045504	dynein heavy chain binding	4/5347	15/18639	0.266666666666667	0.929567982046007	0.663541808069564	1
GO:0003678	DNA helicase activity	20/5347	74/18639	0.27027027027027	0.942129711533115	0.666379598506178	1
GO:0043177	organic acid binding	52/5347	189/18639	0.275132275132275	0.959078076714134	0.666461175590242	1
GO:0004540	RNA nuclease activity	33/5347	121/18639	0.272727272727273	0.950694527092507	0.667944047498451	1
GO:0051082	unfolded protein binding	33/5347	121/18639	0.272727272727273	0.950694527092507	0.667944047498451	1
GO:0051539	4 iron, 4 sulfur cluster binding	12/5347	45/18639	0.266666666666667	0.929567982046007	0.67204836647171	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/5347	19/18639	0.263157894736842	0.917336824387507	0.674157789146165	1
GO:0005520	insulin-like growth factor binding	5/5347	19/18639	0.263157894736842	0.917336824387507	0.674157789146165	1
GO:0022821	solute:potassium antiporter activity	5/5347	19/18639	0.263157894736842	0.917336824387507	0.674157789146165	1
GO:0022840	leak channel activity	5/5347	19/18639	0.263157894736842	0.917336824387507	0.674157789146165	1
GO:0022842	narrow pore channel activity	5/5347	19/18639	0.263157894736842	0.917336824387507	0.674157789146165	1
GO:0050145	nucleoside monophosphate kinase activity	5/5347	19/18639	0.263157894736842	0.917336824387507	0.674157789146165	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	9/5347	34/18639	0.264705882352941	0.922732923354492	0.674856619846971	1
GO:0090482	vitamin transmembrane transporter activity	9/5347	34/18639	0.264705882352941	0.922732923354492	0.674856619846971	1
GO:0003727	single-stranded RNA binding	24/5347	89/18639	0.269662921348315	0.94001256611394	0.678662866274256	1
GO:0004602	glutathione peroxidase activity	6/5347	23/18639	0.260869565217391	0.909359982436311	0.684230330732254	1
GO:0005501	retinoid binding	10/5347	38/18639	0.263157894736842	0.917336824387507	0.685321084301187	1
GO:0019840	isoprenoid binding	10/5347	38/18639	0.263157894736842	0.917336824387507	0.685321084301187	1
GO:0042887	amide transmembrane transporter activity	10/5347	38/18639	0.263157894736842	0.917336824387507	0.685321084301187	1
GO:0015291	secondary active transmembrane transporter activity	79/5347	287/18639	0.275261324041812	0.959527925718222	0.690446734491507	1
GO:0001671	ATPase activator activity	7/5347	27/18639	0.259259259259259	0.903746649211396	0.693744544738515	1
GO:0008266	poly(U) RNA binding	7/5347	27/18639	0.259259259259259	0.903746649211396	0.693744544738515	1
GO:0016405	CoA-ligase activity	7/5347	27/18639	0.259259259259259	0.903746649211396	0.693744544738515	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	7/5347	27/18639	0.259259259259259	0.903746649211396	0.693744544738515	1
GO:0072349	modified amino acid transmembrane transporter activity	8/5347	31/18639	0.258064516129032	0.899581918109039	0.702732946461976	1
GO:0043022	ribosome binding	30/5347	112/18639	0.267857142857143	0.933717839108712	0.705530224503854	1
GO:0000175	3'-5'-RNA exonuclease activity	9/5347	35/18639	0.257142857142857	0.896369125544364	0.711239336470818	1
GO:0003995	acyl-CoA dehydrogenase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0004300	enoyl-CoA hydratase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0005527	macrolide binding	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0015166	polyol transmembrane transporter activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0016208	AMP binding	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0016273	arginine N-methyltransferase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0016274	protein-arginine N-methyltransferase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0140900	chloride:bicarbonate antiporter activity	3/5347	12/18639	0.25	0.871469983168132	0.714521363551898	1
GO:0003688	DNA replication origin binding	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0015385	sodium:proton antiporter activity	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0016722	oxidoreductase activity, acting on metal ions	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0017070	U6 snRNA binding	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0022841	potassium ion leak channel activity	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0043023	ribosomal large subunit binding	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0140328	floppase activity	4/5347	16/18639	0.25	0.871469983168132	0.716866296768214	1
GO:0120013	lipid transfer activity	17/5347	65/18639	0.261538461538462	0.911691674698969	0.717805371992592	1
GO:0019001	guanyl nucleotide binding	110/5347	400/18639	0.275	0.958616981484945	0.719536161309353	1
GO:0032561	guanyl ribonucleotide binding	110/5347	400/18639	0.275	0.958616981484945	0.719536161309353	1
GO:0000339	RNA cap binding	5/5347	20/18639	0.25	0.871469983168132	0.721420835821451	1
GO:0140664	ATP-dependent DNA damage sensor activity	5/5347	20/18639	0.25	0.871469983168132	0.721420835821451	1
GO:0005540	hyaluronic acid binding	6/5347	24/18639	0.25	0.871469983168132	0.726920735541908	1
GO:0070300	phosphatidic acid binding	6/5347	24/18639	0.25	0.871469983168132	0.726920735541908	1
GO:0140612	DNA damage sensor activity	6/5347	24/18639	0.25	0.871469983168132	0.726920735541908	1
GO:0005242	inward rectifier potassium channel activity	7/5347	28/18639	0.25	0.871469983168132	0.732818032711984	1
GO:0051537	2 iron, 2 sulfur cluster binding	7/5347	28/18639	0.25	0.871469983168132	0.732818032711984	1
GO:0140359	ABC-type transporter activity	12/5347	47/18639	0.25531914893617	0.890011897703624	0.734283921786049	1
GO:0019842	vitamin binding	40/5347	150/18639	0.266666666666667	0.929567982046007	0.736374970659412	1
GO:0042910	xenobiotic transmembrane transporter activity	8/5347	32/18639	0.25	0.871469983168132	0.738847027478807	1
GO:0045505	dynein intermediate chain binding	9/5347	36/18639	0.25	0.871469983168132	0.744869816486303	1
GO:0016779	nucleotidyltransferase activity	36/5347	136/18639	0.264705882352941	0.922732923354492	0.745728354666494	1
GO:0001618	virus receptor activity	21/5347	81/18639	0.259259259259259	0.903746649211396	0.746580134902389	1
GO:0031406	carboxylic acid binding	50/5347	187/18639	0.267379679144385	0.932053457933831	0.747668849826281	1
GO:0015036	disulfide oxidoreductase activity	10/5347	40/18639	0.25	0.871469983168132	0.750812118196671	1
GO:0030331	nuclear estrogen receptor binding	10/5347	40/18639	0.25	0.871469983168132	0.750812118196671	1
GO:0071949	FAD binding	10/5347	40/18639	0.25	0.871469983168132	0.750812118196671	1
GO:0019205	nucleobase-containing compound kinase activity	11/5347	44/18639	0.25	0.871469983168132	0.75663354399121	1
GO:0005248	voltage-gated sodium channel activity	5/5347	21/18639	0.238095238095238	0.829971412541078	0.763549271203841	1
GO:0036122	BMP binding	5/5347	21/18639	0.238095238095238	0.829971412541078	0.763549271203841	1
GO:0061891	calcium ion sensor activity	5/5347	21/18639	0.238095238095238	0.829971412541078	0.763549271203841	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0004549	tRNA-specific ribonuclease activity	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0004550	nucleoside diphosphate kinase activity	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0045125	bioactive lipid receptor activity	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0045236	CXCR chemokine receptor binding	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0048038	quinone binding	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0070403	NAD+ binding	4/5347	17/18639	0.235294117647059	0.820207042981771	0.763666933527099	1
GO:0005537	D-mannose binding	6/5347	25/18639	0.24	0.836611183841406	0.765373421979388	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6/5347	25/18639	0.24	0.836611183841406	0.765373421979388	1
GO:0005035	death receptor activity	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:0031994	insulin-like growth factor I binding	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:0071714	icosanoid transmembrane transporter activity	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:1901338	catecholamine binding	3/5347	13/18639	0.230769230769231	0.804433830616737	0.76753497366281	1
GO:0140272	exogenous protein binding	21/5347	82/18639	0.25609756097561	0.892725348611257	0.767802090296511	1
GO:0004181	metallocarboxypeptidase activity	7/5347	29/18639	0.241379310344828	0.841419294093369	0.768279072979191	1
GO:0043236	laminin binding	7/5347	29/18639	0.241379310344828	0.841419294093369	0.768279072979191	1
GO:0140098	catalytic activity, acting on RNA	105/5347	387/18639	0.271317829457364	0.945781377081693	0.769394624067011	1
GO:0030296	protein tyrosine kinase activator activity	8/5347	33/18639	0.242424242424242	0.845061801860007	0.771809185939176	1
GO:0140299	molecular sensor activity	18/5347	71/18639	0.253521126760563	0.883744208283176	0.772012189785215	1
GO:0030170	pyridoxal phosphate binding	14/5347	56/18639	0.25	0.871469983168132	0.773208797799356	1
GO:0005200	structural constituent of cytoskeleton	29/5347	112/18639	0.258928571428571	0.902593911138422	0.774609408055186	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	15/5347	60/18639	0.25	0.871469983168132	0.77842188495176	1
GO:0140303	intramembrane lipid transporter activity	11/5347	45/18639	0.244444444444444	0.852103983542173	0.783999336718108	1
GO:0070279	vitamin B6 binding	14/5347	57/18639	0.245614035087719	0.856181036095007	0.7966819758177	1
GO:0004529	DNA exonuclease activity	6/5347	26/18639	0.230769230769231	0.804433830616737	0.799647523937905	1
GO:0051139	metal cation:proton antiporter activity	6/5347	26/18639	0.230769230769231	0.804433830616737	0.799647523937905	1
GO:0008187	poly-pyrimidine tract binding	7/5347	30/18639	0.233333333333333	0.813371984290256	0.800161118924636	1
GO:0070566	adenylyltransferase activity	7/5347	30/18639	0.233333333333333	0.813371984290256	0.800161118924636	1
GO:0016881	acid-amino acid ligase activity	5/5347	22/18639	0.227272727272727	0.792245439243756	0.800658328444047	1
GO:0034062	5'-3' RNA polymerase activity	5/5347	22/18639	0.227272727272727	0.792245439243756	0.800658328444047	1
GO:0070034	telomerase RNA binding	5/5347	22/18639	0.227272727272727	0.792245439243756	0.800658328444047	1
GO:0097747	RNA polymerase activity	5/5347	22/18639	0.227272727272727	0.792245439243756	0.800658328444047	1
GO:0015035	protein-disulfide reductase activity	8/5347	34/18639	0.235294117647059	0.820207042981771	0.801640744736778	1
GO:0048306	calcium-dependent protein binding	20/5347	80/18639	0.25	0.871469983168132	0.802257501637544	1
GO:0000900	mRNA regulatory element binding translation repressor activity	4/5347	18/18639	0.222222222222222	0.774639985038339	0.804190876573959	1
GO:0008525	phosphatidylcholine transporter activity	4/5347	18/18639	0.222222222222222	0.774639985038339	0.804190876573959	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/5347	18/18639	0.222222222222222	0.774639985038339	0.804190876573959	1
GO:0098641	cadherin binding involved in cell-cell adhesion	4/5347	18/18639	0.222222222222222	0.774639985038339	0.804190876573959	1
GO:0001664	G protein-coupled receptor binding	79/5347	297/18639	0.265993265993266	0.927220588151952	0.806304952899838	1
GO:0022853	active monoatomic ion transmembrane transporter activity	30/5347	118/18639	0.254237288135593	0.886240660848947	0.812007032364823	1
GO:0008559	ABC-type xenobiotic transporter activity	3/5347	14/18639	0.214285714285714	0.74697427128697	0.812211759794663	1
GO:0031404	chloride ion binding	3/5347	14/18639	0.214285714285714	0.74697427128697	0.812211759794663	1
GO:1901474	azole transmembrane transporter activity	3/5347	14/18639	0.214285714285714	0.74697427128697	0.812211759794663	1
GO:1990825	sequence-specific mRNA binding	3/5347	14/18639	0.214285714285714	0.74697427128697	0.812211759794663	1
GO:0004521	RNA endonuclease activity	18/5347	73/18639	0.246575342465753	0.859532038193226	0.812881427706432	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	31/5347	122/18639	0.254098360655738	0.885756376334822	0.816155030495098	1
GO:0008408	3'-5' exonuclease activity	14/5347	58/18639	0.241379310344828	0.841419294093369	0.818363245726028	1
GO:0005343	organic acid:sodium symporter activity	8/5347	35/18639	0.228571428571429	0.796772556039435	0.828426347185951	1
GO:0005452	solute:inorganic anion antiporter activity	7/5347	31/18639	0.225806451612903	0.787134178345409	0.828577669226245	1
GO:0000182	rDNA binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0004935	adrenergic receptor activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0005345	purine nucleobase transmembrane transporter activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0008519	ammonium channel activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0015203	polyamine transmembrane transporter activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0016868	intramolecular phosphotransferase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0031419	cobalamin binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0031996	thioesterase binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0033204	ribonuclease P RNA binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0035374	chondroitin sulfate binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0043121	neurotrophin binding	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0050308	sugar-phosphatase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0070739	protein-glutamic acid ligase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0070740	tubulin-glutamic acid ligase activity	2/5347	10/18639	0.2	0.697175986534505	0.829222796177828	1
GO:0004364	glutathione transferase activity	6/5347	27/18639	0.222222222222222	0.774639985038339	0.829905517994873	1
GO:0005104	fibroblast growth factor receptor binding	6/5347	27/18639	0.222222222222222	0.774639985038339	0.829905517994873	1
GO:0005245	voltage-gated calcium channel activity	10/5347	43/18639	0.232558139534884	0.810669751784308	0.830310767898607	1
GO:0005283	amino acid:sodium symporter activity	5/5347	23/18639	0.217391304347826	0.757799985363593	0.832999438919545	1
GO:0031681	G-protein beta-subunit binding	5/5347	23/18639	0.217391304347826	0.757799985363593	0.832999438919545	1
GO:0004857	enzyme inhibitor activity	111/5347	416/18639	0.266826923076923	0.930126616650602	0.833620074471588	1
GO:0003743	translation initiation factor activity	12/5347	51/18639	0.235294117647059	0.820207042981771	0.833867733142657	1
GO:0008301	DNA binding, bending	4/5347	19/18639	0.210526315789474	0.733869459510006	0.838866366554704	1
GO:0015245	fatty acid transmembrane transporter activity	4/5347	19/18639	0.210526315789474	0.733869459510006	0.838866366554704	1
GO:0031420	alkali metal ion binding	4/5347	19/18639	0.210526315789474	0.733869459510006	0.838866366554704	1
GO:0042577	lipid phosphatase activity	4/5347	19/18639	0.210526315789474	0.733869459510006	0.838866366554704	1
GO:0046624	sphingolipid transporter activity	4/5347	19/18639	0.210526315789474	0.733869459510006	0.838866366554704	1
GO:0050660	flavin adenine dinucleotide binding	21/5347	86/18639	0.244186046511628	0.851203239373524	0.840601710034801	1
GO:0022804	active transmembrane transporter activity	122/5347	457/18639	0.266958424507659	0.930585014849121	0.842657146414304	1
GO:0140101	catalytic activity, acting on a tRNA	35/5347	139/18639	0.251798561151079	0.877739551392363	0.844313201396	1
GO:0005506	iron ion binding	39/5347	154/18639	0.253246753246753	0.882787775157328	0.845301940977817	1
GO:0044183	protein folding chaperone	18/5347	75/18639	0.24	0.836611183841406	0.848191900516635	1
GO:0004129	cytochrome-c oxidase activity	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0008242	omega peptidase activity	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0010181	FMN binding	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0031386	protein tag activity	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0047372	monoacylglycerol lipase activity	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0050700	CARD domain binding	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0141047	molecular tag activity	3/5347	15/18639	0.2	0.697175986534505	0.849379247725937	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	33/5347	132/18639	0.25	0.871469983168132	0.850327941731542	1
GO:0015144	carbohydrate transmembrane transporter activity	9/5347	40/18639	0.225	0.784322984851319	0.85180823975162	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/5347	40/18639	0.225	0.784322984851319	0.85180823975162	1
GO:0003954	NADH dehydrogenase activity	10/5347	44/18639	0.227272727272727	0.792245439243756	0.851980539636077	1
GO:0004033	aldo-keto reductase (NADPH) activity	8/5347	36/18639	0.222222222222222	0.774639985038339	0.852299641671565	1
GO:0015106	bicarbonate transmembrane transporter activity	7/5347	32/18639	0.21875	0.762536235272115	0.853702248915528	1
GO:0051059	NF-kappaB binding	7/5347	32/18639	0.21875	0.762536235272115	0.853702248915528	1
GO:0051119	sugar transmembrane transporter activity	6/5347	28/18639	0.214285714285714	0.74697427128697	0.856383923072025	1
GO:0004806	triacylglycerol lipase activity	5/5347	24/18639	0.208333333333333	0.726224985973443	0.860914887176818	1
GO:0005315	phosphate transmembrane transporter activity	5/5347	24/18639	0.208333333333333	0.726224985973443	0.860914887176818	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	5/5347	24/18639	0.208333333333333	0.726224985973443	0.860914887176818	1
GO:0001614	purinergic nucleotide receptor activity	4/5347	20/18639	0.2	0.697175986534505	0.868227749238017	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/5347	20/18639	0.2	0.697175986534505	0.868227749238017	1
GO:0016408	C-acyltransferase activity	4/5347	20/18639	0.2	0.697175986534505	0.868227749238017	1
GO:0016502	nucleotide receptor activity	4/5347	20/18639	0.2	0.697175986534505	0.868227749238017	1
GO:0043024	ribosomal small subunit binding	4/5347	20/18639	0.2	0.697175986534505	0.868227749238017	1
GO:0001851	complement component C3b binding	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0008199	ferric iron binding	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0010854	adenylate cyclase regulator activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0015205	nucleobase transmembrane transporter activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0019203	carbohydrate phosphatase activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0019206	nucleoside kinase activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0019864	IgG binding	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0047676	arachidonate-CoA ligase activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0050786	RAGE receptor binding	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:1990948	ubiquitin ligase inhibitor activity	2/5347	11/18639	0.181818181818182	0.633796351395005	0.868479036694392	1
GO:0008009	chemokine activity	10/5347	45/18639	0.222222222222222	0.774639985038339	0.871403740469783	1
GO:0004864	protein phosphatase inhibitor activity	12/5347	53/18639	0.226415094339623	0.789255833812648	0.871588391620909	1
GO:0140828	metal cation:monoatomic cation antiporter activity	9/5347	41/18639	0.219512195121951	0.765193155952506	0.872060985382201	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	14/5347	61/18639	0.229508196721311	0.800038017334678	0.873090436859424	1
GO:0030551	cyclic nucleotide binding	8/5347	37/18639	0.216216216216216	0.753703769226492	0.873430074119536	1
GO:0003785	actin monomer binding	6/5347	29/18639	0.206896551724138	0.721216537794316	0.879367797009286	1
GO:0004629	phospholipase C activity	6/5347	29/18639	0.206896551724138	0.721216537794316	0.879367797009286	1
GO:0106222	lncRNA binding	6/5347	29/18639	0.206896551724138	0.721216537794316	0.879367797009286	1
GO:0005149	interleukin-1 receptor binding	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0008296	3'-5'-DNA exonuclease activity	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0015562	efflux transmembrane transporter activity	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0022858	alanine transmembrane transporter activity	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0055102	lipase inhibitor activity	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0140327	flippase activity	3/5347	16/18639	0.1875	0.653602487376099	0.879959159485412	1
GO:0015271	outward rectifier potassium channel activity	5/5347	25/18639	0.2	0.697175986534505	0.884800253476175	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	5/5347	25/18639	0.2	0.697175986534505	0.884800253476175	1
GO:0015645	fatty acid ligase activity	5/5347	25/18639	0.2	0.697175986534505	0.884800253476175	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	5/5347	25/18639	0.2	0.697175986534505	0.884800253476175	1
GO:0120515	fatty acid-CoA ligase activity	5/5347	25/18639	0.2	0.697175986534505	0.884800253476175	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	13/5347	58/18639	0.224137931034483	0.781317915943842	0.887769323704781	1
GO:0015399	primary active transmembrane transporter activity	41/5347	166/18639	0.246987951807229	0.860970344816708	0.891458170587291	1
GO:0019200	carbohydrate kinase activity	4/5347	21/18639	0.19047619047619	0.663977130032862	0.892857979363706	1
GO:0031210	phosphatidylcholine binding	6/5347	30/18639	0.2	0.697175986534505	0.899169466530448	1
GO:0048019	receptor antagonist activity	6/5347	30/18639	0.2	0.697175986534505	0.899169466530448	1
GO:0000340	RNA 7-methylguanosine cap binding	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0003720	telomerase activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0004032	aldose reductase (NADPH) activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0004526	ribonuclease P activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0004859	phospholipase inhibitor activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0004875	complement receptor activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0010853	cyclase activator activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0015132	prostaglandin transmembrane transporter activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0016840	carbon-nitrogen lyase activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0042301	phosphate ion binding	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0097371	MDM2/MDM4 family protein binding	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:0097677	STAT family protein binding	2/5347	12/18639	0.166666666666667	0.580979988778754	0.899270571322891	1
GO:1901682	sulfur compound transmembrane transporter activity	14/5347	63/18639	0.222222222222222	0.774639985038339	0.901668372348143	1
GO:0015459	potassium channel regulator activity	13/5347	59/18639	0.220338983050847	0.768075239402421	0.901753325706356	1
GO:0005272	sodium channel activity	11/5347	51/18639	0.215686274509804	0.751856456066623	0.902871162200934	1
GO:0033293	monocarboxylic acid binding	18/5347	79/18639	0.227848101265823	0.794251123900069	0.903340181968298	1
GO:0005504	fatty acid binding	10/5347	47/18639	0.212765957446809	0.741676581419687	0.904057413817106	1
GO:0008569	minus-end-directed microtubule motor activity	3/5347	17/18639	0.176470588235294	0.615155282236328	0.904878922190764	1
GO:0030548	acetylcholine receptor regulator activity	3/5347	17/18639	0.176470588235294	0.615155282236328	0.904878922190764	1
GO:0070402	NADPH binding	3/5347	17/18639	0.176470588235294	0.615155282236328	0.904878922190764	1
GO:1990226	histone methyltransferase binding	3/5347	17/18639	0.176470588235294	0.615155282236328	0.904878922190764	1
GO:0004435	phosphatidylinositol phospholipase C activity	5/5347	26/18639	0.192307692307692	0.670361525513947	0.905074712890049	1
GO:0015145	monosaccharide transmembrane transporter activity	5/5347	26/18639	0.192307692307692	0.670361525513947	0.905074712890049	1
GO:0003774	cytoskeletal motor activity	37/5347	153/18639	0.241830065359477	0.842990571953487	0.909466035954847	1
GO:0005243	gap junction channel activity	4/5347	22/18639	0.181818181818182	0.633796351395005	0.913346790679185	1
GO:0008970	phospholipase A1 activity	4/5347	22/18639	0.181818181818182	0.633796351395005	0.913346790679185	1
GO:0015377	chloride:monoatomic cation symporter activity	4/5347	22/18639	0.181818181818182	0.633796351395005	0.913346790679185	1
GO:0003777	microtubule motor activity	15/5347	68/18639	0.220588235294118	0.76894410279541	0.913663249485301	1
GO:0051536	iron-sulfur cluster binding	17/5347	76/18639	0.223684210526316	0.779736300729381	0.913885385235675	1
GO:0000049	tRNA binding	18/5347	80/18639	0.225	0.784322984851319	0.914225987762621	1
GO:0019212	phosphatase inhibitor activity	12/5347	56/18639	0.214285714285714	0.74697427128697	0.914989614539902	1
GO:0008395	steroid hydroxylase activity	5/5347	27/18639	0.185185185185185	0.645533320865283	0.922158620820771	1
GO:0140662	ATP-dependent protein folding chaperone	8/5347	40/18639	0.2	0.697175986534505	0.92236093051453	1
GO:0002161	aminoacyl-tRNA editing activity	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0003964	RNA-directed DNA polymerase activity	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0004465	lipoprotein lipase activity	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0005542	folic acid binding	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0035325	Toll-like receptor binding	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0071837	HMG box domain binding	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0140333	glycerophospholipid flippase activity	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0140666	annealing activity	2/5347	13/18639	0.153846153846154	0.536289220411158	0.923222498170179	1
GO:0051540	metal cluster binding	17/5347	77/18639	0.220779220779221	0.769609855265363	0.923993667231297	1
GO:0003746	translation elongation factor activity	3/5347	18/18639	0.166666666666667	0.580979988778754	0.925016531314126	1
GO:0015280	ligand-gated sodium channel activity	3/5347	18/18639	0.166666666666667	0.580979988778754	0.925016531314126	1
GO:0017128	phospholipid scramblase activity	3/5347	18/18639	0.166666666666667	0.580979988778754	0.925016531314126	1
GO:0070628	proteasome binding	3/5347	18/18639	0.166666666666667	0.580979988778754	0.925016531314126	1
GO:0099602	neurotransmitter receptor regulator activity	3/5347	18/18639	0.166666666666667	0.580979988778754	0.925016531314126	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/5347	36/18639	0.194444444444444	0.677809986908547	0.925911895384973	1
GO:0051015	actin filament binding	51/5347	209/18639	0.244019138755981	0.850621418977506	0.928906433000844	1
GO:0015171	amino acid transmembrane transporter activity	23/5347	102/18639	0.225490196078431	0.786031749524197	0.933975760452572	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/5347	41/18639	0.195121951219512	0.680171694180005	0.934554856607215	1
GO:0008574	plus-end-directed microtubule motor activity	3/5347	19/18639	0.157894736842105	0.550402094632504	0.941169687206517	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/5347	19/18639	0.157894736842105	0.550402094632504	0.941169687206517	1
GO:0042834	peptidoglycan binding	3/5347	19/18639	0.157894736842105	0.550402094632504	0.941169687206517	1
GO:0008195	phosphatidate phosphatase activity	2/5347	14/18639	0.142857142857143	0.497982847524647	0.941724287899432	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/5347	46/18639	0.195652173913043	0.682019986827234	0.942157287846716	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/5347	33/18639	0.181818181818182	0.633796351395005	0.942683243595196	1
GO:0019956	chemokine binding	6/5347	33/18639	0.181818181818182	0.633796351395005	0.942683243595196	1
GO:0015149	hexose transmembrane transporter activity	4/5347	24/18639	0.166666666666667	0.580979988778754	0.944131449718936	1
GO:0055056	D-glucose transmembrane transporter activity	4/5347	24/18639	0.166666666666667	0.580979988778754	0.944131449718936	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/5347	59/18639	0.203389830508475	0.708992528679158	0.94533821609404	1
GO:0052689	carboxylic ester hydrolase activity	20/5347	92/18639	0.217391304347826	0.757799985363593	0.947671982150873	1
GO:0005416	amino acid:monoatomic cation symporter activity	5/5347	29/18639	0.172413793103448	0.601013781495263	0.948351149646657	1
GO:0000146	microfilament motor activity	7/5347	38/18639	0.184210526315789	0.642135777071255	0.948577830700644	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	14/5347	68/18639	0.205882352941176	0.71768116260905	0.950675126177487	1
GO:0140375	immune receptor activity	36/5347	156/18639	0.230769230769231	0.804433830616737	0.95244978626042	1
GO:0015020	glucuronosyltransferase activity	6/5347	34/18639	0.176470588235294	0.615155282236328	0.952908797782077	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/5347	34/18639	0.176470588235294	0.615155282236328	0.952908797782077	1
GO:0051427	hormone receptor binding	6/5347	34/18639	0.176470588235294	0.615155282236328	0.952908797782077	1
GO:0010851	cyclase regulator activity	3/5347	20/18639	0.15	0.522881989900879	0.954041793906841	1
GO:0042288	MHC class I protein binding	3/5347	20/18639	0.15	0.522881989900879	0.954041793906841	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0015116	sulfate transmembrane transporter activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0015250	water channel activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0017081	chloride channel regulator activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0034483	heparan sulfate sulfotransferase activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0140161	monocarboxylate:sodium symporter activity	2/5347	15/18639	0.133333333333333	0.464783991023003	0.955931217156892	1
GO:0098918	structural constituent of synapse	5/5347	30/18639	0.166666666666667	0.580979988778754	0.958187486269898	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	9/5347	48/18639	0.1875	0.653602487376099	0.958933349115278	1
GO:0008514	organic anion transmembrane transporter activity	65/5347	269/18639	0.241635687732342	0.842312994883696	0.959133438098301	1
GO:0015293	symporter activity	33/5347	146/18639	0.226027397260274	0.78790436834379	0.960218929742888	1
GO:0030547	signaling receptor inhibitor activity	8/5347	44/18639	0.181818181818182	0.633796351395005	0.961642939090294	1
GO:0015125	bile acid transmembrane transporter activity	3/5347	21/18639	0.142857142857143	0.497982847524647	0.964239096330697	1
GO:1904047	S-adenosyl-L-methionine binding	3/5347	21/18639	0.142857142857143	0.497982847524647	0.964239096330697	1
GO:0008135	translation factor activity, RNA binding	17/5347	83/18639	0.204819277108434	0.713975407896782	0.965915110821397	1
GO:0003796	lysozyme activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0004983	neuropeptide Y receptor activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0005337	nucleoside transmembrane transporter activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0019531	oxalate transmembrane transporter activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0140940	histone H2A methyltransferase activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/5347	10/18639	0.1	0.348587993267253	0.966017503357603	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/5347	31/18639	0.161290322580645	0.562238698818149	0.96627902249806	1
GO:0015378	sodium:chloride symporter activity	2/5347	16/18639	0.125	0.435734991584066	0.966784368252818	1
GO:0015294	solute:monoatomic cation symporter activity	25/5347	116/18639	0.21551724137931	0.751267226869079	0.967600310251176	1
GO:0046873	metal ion transmembrane transporter activity	112/5347	450/18639	0.248888888888889	0.86759678324294	0.969614714731705	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	18/5347	88/18639	0.204545454545455	0.713020895319381	0.969802534413199	1
GO:0180051	translation factor activity	17/5347	84/18639	0.202380952380952	0.705475700659916	0.970427324646419	1
GO:0004620	phospholipase activity	23/5347	109/18639	0.211009174311927	0.735552646343744	0.971743762473393	1
GO:0036002	pre-mRNA binding	11/5347	59/18639	0.186440677966102	0.649909817955895	0.972384780617319	1
GO:0016298	lipase activity	28/5347	130/18639	0.215384615384615	0.750804908575621	0.974326049120043	1
GO:0009881	photoreceptor activity	2/5347	17/18639	0.117647058823529	0.410103521490886	0.975038427727758	1
GO:0036041	long-chain fatty acid binding	2/5347	17/18639	0.117647058823529	0.410103521490886	0.975038427727758	1
GO:0005319	lipid transporter activity	40/5347	178/18639	0.224719101123595	0.78334380509495	0.975117766325698	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0005536	D-glucose binding	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0008503	benzodiazepine receptor activity	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0016594	glycine binding	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0034511	U3 snoRNA binding	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/5347	11/18639	0.0909090909090909	0.316898175697502	0.975771350023924	1
GO:0031492	nucleosomal DNA binding	7/5347	42/18639	0.166666666666667	0.580979988778754	0.976270844013465	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/5347	60/18639	0.183333333333333	0.63907798765663	0.976712730031885	1
GO:0061134	peptidase regulator activity	52/5347	226/18639	0.230088495575221	0.802060869464475	0.977618256815663	1
GO:0016209	antioxidant activity	17/5347	86/18639	0.197674418604651	0.689069289016662	0.977888214682563	1
GO:0042923	neuropeptide binding	5/5347	33/18639	0.151515151515152	0.528163626162504	0.978298492790462	1
GO:0099186	structural constituent of postsynapse	3/5347	23/18639	0.130434782608696	0.454679991218156	0.978576628675367	1
GO:0140102	catalytic activity, acting on a rRNA	3/5347	23/18639	0.130434782608696	0.454679991218156	0.978576628675367	1
GO:0043531	ADP binding	6/5347	38/18639	0.157894736842105	0.550402094632504	0.979300745204988	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	9/5347	52/18639	0.173076923076923	0.603325372962553	0.980063309554266	1
GO:0016836	hydro-lyase activity	11/5347	61/18639	0.180327868852459	0.62860129933439	0.980414653758486	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	13/5347	70/18639	0.185714285714286	0.647377701782041	0.981263833052422	1
GO:0005372	water transmembrane transporter activity	2/5347	18/18639	0.111111111111111	0.38731999251917	0.981291164779462	1
GO:0015373	monoatomic anion:sodium symporter activity	2/5347	18/18639	0.111111111111111	0.38731999251917	0.981291164779462	1
GO:0004601	peroxidase activity	10/5347	57/18639	0.175438596491228	0.611557882925005	0.981871273808154	1
GO:0038187	pattern recognition receptor activity	8/5347	48/18639	0.166666666666667	0.580979988778754	0.982025909194984	1
GO:0015269	calcium-activated potassium channel activity	1/5347	12/18639	0.0833333333333333	0.290489994389377	0.982725966269473	1
GO:1990817	poly(A) RNA polymerase activity	1/5347	12/18639	0.0833333333333333	0.290489994389377	0.982725966269473	1
GO:0030246	carbohydrate binding	65/5347	280/18639	0.232142857142857	0.809222127227551	0.983926384168328	1
GO:0046982	protein heterodimerization activity	88/5347	369/18639	0.238482384823848	0.83132095955334	0.984823061550803	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/5347	19/18639	0.105263157894737	0.366934729755003	0.986011338611574	1
GO:0034987	immunoglobulin receptor binding	2/5347	19/18639	0.105263157894737	0.366934729755003	0.986011338611574	1
GO:0141147	intracellularly calcium-gated channel activity	2/5347	19/18639	0.105263157894737	0.366934729755003	0.986011338611574	1
GO:0050997	quaternary ammonium group binding	6/5347	40/18639	0.15	0.522881989900879	0.986538842994225	1
GO:0046943	carboxylic acid transmembrane transporter activity	41/5347	188/18639	0.218085106382979	0.760218495955179	0.987013200529507	1
GO:0005251	delayed rectifier potassium channel activity	3/5347	25/18639	0.12	0.418305591920703	0.987324378331372	1
GO:0005548	phospholipid transporter activity	12/5347	68/18639	0.176470588235294	0.615155282236328	0.987524290297021	1
GO:0004993	G protein-coupled serotonin receptor activity	1/5347	13/18639	0.0769230769230769	0.268144610205579	0.987684588611081	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/5347	13/18639	0.0769230769230769	0.268144610205579	0.987684588611081	1
GO:0005342	organic acid transmembrane transporter activity	41/5347	189/18639	0.216931216931217	0.75619617587076	0.988384932483988	1
GO:0015078	proton transmembrane transporter activity	40/5347	185/18639	0.216216216216216	0.753703769226492	0.988389702235744	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	5/5347	36/18639	0.138888888888889	0.484149990648962	0.989059215777492	1
GO:0001530	lipopolysaccharide binding	6/5347	41/18639	0.146341463414634	0.510128770635004	0.989191437328891	1
GO:0008227	G protein-coupled amine receptor activity	6/5347	41/18639	0.146341463414634	0.510128770635004	0.989191437328891	1
GO:0042287	MHC protein binding	6/5347	41/18639	0.146341463414634	0.510128770635004	0.989191437328891	1
GO:0047499	calcium-independent phospholipase A2 activity	4/5347	31/18639	0.129032258064516	0.44979095905452	0.989345630297026	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/5347	20/18639	0.1	0.348587993267253	0.989563510245433	1
GO:0019865	immunoglobulin binding	3/5347	26/18639	0.115384615384615	0.402216915308368	0.990289912695029	1
GO:0120014	phospholipid transfer activity	3/5347	26/18639	0.115384615384615	0.402216915308368	0.990289912695029	1
GO:0019843	rRNA binding	11/5347	65/18639	0.169230769230769	0.589918142452274	0.990444644178245	1
GO:0170055	lipid transmembrane transporter activity	9/5347	56/18639	0.160714285714286	0.560230703465228	0.990744405699518	1
GO:0005344	oxygen carrier activity	1/5347	14/18639	0.0714285714285714	0.248991423762323	0.991219996358131	1
GO:0008392	arachidonate epoxygenase activity	1/5347	14/18639	0.0714285714285714	0.248991423762323	0.991219996358131	1
GO:0015926	glucosidase activity	1/5347	14/18639	0.0714285714285714	0.248991423762323	0.991219996358131	1
GO:0019763	immunoglobulin receptor activity	1/5347	14/18639	0.0714285714285714	0.248991423762323	0.991219996358131	1
GO:0061783	peptidoglycan muralytic activity	1/5347	14/18639	0.0714285714285714	0.248991423762323	0.991219996358131	1
GO:0022829	wide pore channel activity	5/5347	37/18639	0.135135135135135	0.471064855766558	0.991341943445178	1
GO:0016835	carbon-oxygen lyase activity	14/5347	79/18639	0.177215189873418	0.617750874144498	0.991388856837592	1
GO:0030515	snoRNA binding	4/5347	32/18639	0.125	0.435734991584066	0.991694685637688	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/5347	32/18639	0.125	0.435734991584066	0.991694685637688	1
GO:0016829	lyase activity	43/5347	200/18639	0.215	0.749464185524593	0.991708872430595	1
GO:0001846	opsonin binding	2/5347	21/18639	0.0952380952380952	0.331988565016431	0.992229238025931	1
GO:0051428	peptide hormone receptor binding	2/5347	21/18639	0.0952380952380952	0.331988565016431	0.992229238025931	1
GO:0070182	DNA polymerase binding	2/5347	21/18639	0.0952380952380952	0.331988565016431	0.992229238025931	1
GO:0005125	cytokine activity	51/5347	234/18639	0.217948717948718	0.75974306224914	0.993355686570481	1
GO:0005544	calcium-dependent phospholipid binding	8/5347	53/18639	0.150943396226415	0.526170555875098	0.993457875313037	1
GO:0004089	carbonate dehydratase activity	1/5347	15/18639	0.0666666666666667	0.232391995511502	0.993740623443933	1
GO:0016846	carbon-sulfur lyase activity	1/5347	15/18639	0.0666666666666667	0.232391995511502	0.993740623443933	1
GO:0030553	cGMP binding	1/5347	15/18639	0.0666666666666667	0.232391995511502	0.993740623443933	1
GO:0008649	rRNA methyltransferase activity	2/5347	22/18639	0.0909090909090909	0.316898175697502	0.994224689474641	1
GO:0033691	sialic acid binding	2/5347	22/18639	0.0909090909090909	0.316898175697502	0.994224689474641	1
GO:0020037	heme binding	28/5347	142/18639	0.197183098591549	0.68735660644247	0.994571643976248	1
GO:0015079	potassium ion transmembrane transporter activity	32/5347	160/18639	0.2	0.697175986534505	0.995460492573906	1
GO:0008391	arachidonate monooxygenase activity	1/5347	16/18639	0.0625	0.217867495792033	0.995537707123341	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/5347	16/18639	0.0625	0.217867495792033	0.995537707123341	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/5347	16/18639	0.0625	0.217867495792033	0.995537707123341	1
GO:0046906	tetrapyrrole binding	30/5347	152/18639	0.197368421052632	0.68800261829063	0.995664464243028	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/5347	23/18639	0.0869565217391304	0.303119994145437	0.995714980979334	1
GO:0005254	chloride channel activity	14/5347	83/18639	0.168674698795181	0.587979747679703	0.99572815275906	1
GO:0004623	phospholipase A2 activity	4/5347	35/18639	0.114285714285714	0.398386278019717	0.996124007975294	1
GO:0004812	aminoacyl-tRNA ligase activity	5/5347	41/18639	0.121951219512195	0.425107308862503	0.996688541861535	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/5347	41/18639	0.121951219512195	0.425107308862503	0.996688541861535	1
GO:0022839	monoatomic ion-gated channel activity	3/5347	30/18639	0.1	0.348587993267253	0.996733561349114	1
GO:0022832	voltage-gated channel activity	35/5347	175/18639	0.2	0.697175986534505	0.996759834158773	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/5347	17/18639	0.0588235294117647	0.205051760745443	0.996818912085565	1
GO:0070492	oligosaccharide binding	1/5347	17/18639	0.0588235294117647	0.205051760745443	0.996818912085565	1
GO:0019957	C-C chemokine binding	2/5347	24/18639	0.0833333333333333	0.290489994389377	0.99682567302052	1
GO:0009055	electron transfer activity	21/5347	116/18639	0.181034482758621	0.631064470570026	0.996946376591922	1
GO:0022843	voltage-gated monoatomic cation channel activity	27/5347	143/18639	0.188811188811189	0.658173134140967	0.997432401893382	1
GO:0042379	chemokine receptor binding	11/5347	72/18639	0.152777777777778	0.532564989713858	0.997505040421525	1
GO:0005244	voltage-gated monoatomic ion channel activity	34/5347	173/18639	0.196531791907514	0.685086229542578	0.997580106149149	1
GO:0008236	serine-type peptidase activity	39/5347	194/18639	0.201030927835052	0.700769677186745	0.997638313929466	1
GO:0001848	complement binding	2/5347	25/18639	0.08	0.278870394613802	0.997651872558707	1
GO:0004970	glutamate-gated receptor activity	1/5347	18/18639	0.0555555555555556	0.193659996259585	0.997732308985924	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/5347	18/18639	0.0555555555555556	0.193659996259585	0.997732308985924	1
GO:0032393	MHC class I receptor activity	1/5347	18/18639	0.0555555555555556	0.193659996259585	0.997732308985924	1
GO:0099094	ligand-gated monoatomic cation channel activity	25/5347	136/18639	0.183823529411765	0.640786752329509	0.997980640728174	1
GO:0004497	monooxygenase activity	18/5347	106/18639	0.169811320754717	0.591941875359486	0.998226383578701	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/5347	26/18639	0.0769230769230769	0.268144610205579	0.998265369214014	1
GO:0004950	chemokine receptor activity	2/5347	26/18639	0.0769230769230769	0.268144610205579	0.998265369214014	1
GO:0005227	calcium-activated cation channel activity	2/5347	26/18639	0.0769230769230769	0.268144610205579	0.998265369214014	1
GO:0061135	endopeptidase regulator activity	36/5347	184/18639	0.195652173913043	0.682019986827234	0.998308115321988	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/5347	19/18639	0.0526315789473684	0.183467364877501	0.998383474006721	1
GO:0099589	serotonin receptor activity	1/5347	19/18639	0.0526315789473684	0.183467364877501	0.998383474006721	1
GO:0005249	voltage-gated potassium channel activity	16/5347	98/18639	0.163265306122449	0.569123254313882	0.998530201560635	1
GO:0015081	sodium ion transmembrane transporter activity	31/5347	164/18639	0.189024390243902	0.65891632873688	0.998558546351918	1
GO:0017171	serine hydrolase activity	39/5347	198/18639	0.196969696969697	0.686612714011255	0.998608402497428	1
GO:0005253	monoatomic anion channel activity	17/5347	103/18639	0.16504854368932	0.575339406363427	0.998642549513583	1
GO:0015108	chloride transmembrane transporter activity	21/5347	121/18639	0.173553719008264	0.604987426331596	0.998651322562078	1
GO:0030414	peptidase inhibitor activity	32/5347	169/18639	0.189349112426035	0.660048271275271	0.998705388597605	1
GO:0015464	acetylcholine receptor activity	1/5347	20/18639	0.05	0.174293996633626	0.998847682625736	1
GO:0030627	pre-mRNA 5'-splice site binding	1/5347	20/18639	0.05	0.174293996633626	0.998847682625736	1
GO:0071855	neuropeptide receptor binding	4/5347	40/18639	0.1	0.348587993267253	0.998956876032178	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/5347	46/18639	0.108695652173913	0.378899992681796	0.99905118443967	1
GO:0008527	taste receptor activity	2/5347	28/18639	0.0714285714285714	0.248991423762323	0.999056854289069	1
GO:0016874	ligase activity	31/5347	167/18639	0.18562874251497	0.64707950846017	0.999073994736418	1
GO:0004252	serine-type endopeptidase activity	33/5347	176/18639	0.1875	0.653602487376099	0.999130741930048	1
GO:0005267	potassium channel activity	21/5347	124/18639	0.169354838709677	0.590350633759057	0.999188429201012	1
GO:0015103	inorganic anion transmembrane transporter activity	30/5347	165/18639	0.181818181818182	0.633796351395005	0.999348138394174	1
GO:0004866	endopeptidase inhibitor activity	29/5347	161/18639	0.180124223602484	0.62789141644412	0.999382183991129	1
GO:0033038	bitter taste receptor activity	1/5347	22/18639	0.0454545454545455	0.158449087848751	0.999414505588159	1
GO:0008188	neuropeptide receptor activity	5/5347	48/18639	0.104166666666667	0.363112492986722	0.999431869238177	1
GO:0016493	C-C chemokine receptor activity	1/5347	23/18639	0.0434782608695652	0.151559997072719	0.999582665797651	1
GO:0016917	GABA receptor activity	1/5347	23/18639	0.0434782608695652	0.151559997072719	0.999582665797651	1
GO:0001653	peptide receptor activity	21/5347	128/18639	0.1640625	0.571902176454086	0.999595578121875	1
GO:0008509	monoatomic anion transmembrane transporter activity	25/5347	149/18639	0.167785234899329	0.584879183334317	0.999756188470621	1
GO:0008528	G protein-coupled peptide receptor activity	19/5347	122/18639	0.155737704918033	0.542882940334246	0.999773844527368	1
GO:0015370	solute:sodium symporter activity	10/5347	79/18639	0.126582278481013	0.441250624388927	0.999801237024492	1
GO:0008066	glutamate receptor activity	1/5347	26/18639	0.0384615384615385	0.13407230510279	0.999848883723462	1
GO:0019825	oxygen binding	2/5347	34/18639	0.0588235294117647	0.205051760745443	0.999852059348669	1
GO:0015252	proton channel activity	1/5347	27/18639	0.037037037037037	0.129106664173057	0.999892295249312	1
GO:0048020	CCR chemokine receptor binding	4/5347	50/18639	0.08	0.278870394613802	0.999933036541283	1
GO:0004867	serine-type endopeptidase inhibitor activity	12/5347	95/18639	0.126315789473684	0.440321675706003	0.999945306744182	1
GO:0005184	neuropeptide hormone activity	1/5347	31/18639	0.032258064516129	0.11244773976363	0.999972213409646	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/5347	47/18639	0.0638297872340425	0.222502974425906	0.999975948071729	1
GO:0160041	neuropeptide activity	1/5347	32/18639	0.03125	0.108933747896016	0.999980197873244	1
GO:0005261	monoatomic cation channel activity	65/5347	341/18639	0.190615835777126	0.664463916785086	0.999985667312889	1
GO:0005179	hormone activity	18/5347	132/18639	0.136363636363636	0.475347263546254	0.999987714362342	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	4/5347	56/18639	0.0714285714285714	0.248991423762323	0.999987831428662	1
GO:0098960	postsynaptic neurotransmitter receptor activity	6/5347	69/18639	0.0869565217391304	0.303119994145437	0.999989599787814	1
GO:0022834	ligand-gated channel activity	29/5347	188/18639	0.154255319148936	0.537715521529273	0.999993798709381	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/5347	53/18639	0.0566037735849057	0.197313958453162	0.999996039018742	1
GO:0015276	ligand-gated monoatomic ion channel activity	28/5347	186/18639	0.150537634408602	0.52475611889694	0.99999622793938	1
GO:0030280	structural constituent of skin epidermis	1/5347	37/18639	0.027027027027027	0.0942129711533115	0.999996361238997	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	6/5347	73/18639	0.0821917808219178	0.286510679397742	0.999996465153793	1
GO:0030594	neurotransmitter receptor activity	9/5347	97/18639	0.0927835051546392	0.323432158701575	0.999999315956344	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/5347	63/18639	0.0476190476190476	0.165994282508216	0.999999813997885	1
GO:0022835	transmitter-gated channel activity	3/5347	63/18639	0.0476190476190476	0.165994282508216	0.999999813997885	1
GO:0022836	gated channel activity	53/5347	318/18639	0.166666666666667	0.580979988778754	0.999999828750246	1
GO:0003823	antigen binding	22/5347	174/18639	0.126436781609195	0.440743439763193	0.99999988275312	1
GO:0005216	monoatomic ion channel activity	82/5347	448/18639	0.183035714285714	0.638040523390954	0.999999893061649	1
GO:0003730	mRNA 3'-UTR binding	35/5347	262/18639	0.133587786259542	0.465670983372284	0.999999999087062	1
GO:0003735	structural constituent of ribosome	7/5347	175/18639	0.04	0.139435197306901	1	1
GO:0030371	translation repressor activity	10/5347	329/18639	0.0303951367781155	0.10595379734567	1	1
GO:0045182	translation regulator activity	18/5347	356/18639	0.050561797752809	0.176252356146364	1	1
GO:1903231	mRNA base-pairing translational repressor activity	1/5347	298/18639	0.00335570469798658	0.0116975836666863	1	1