ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	185/3991	495/18639	0.373737373737374	1.74544998974966	1.56970481600889e-16	1.93464857546424e-13
GO:0004842	ubiquitin-protein transferase activity	171/3991	449/18639	0.380846325167038	1.77865062760923	2.89834992578912e-16	1.93464857546424e-13
GO:0019787	ubiquitin-like protein transferase activity	179/3991	479/18639	0.373695198329854	1.74525301971189	4.98155850861601e-16	2.21679353633412e-13
GO:0016755	aminoacyltransferase activity	181/3991	496/18639	0.36491935483871	1.70426756573258	4.80960646850221e-15	1.60520615886261e-12
GO:0060589	nucleoside-triphosphatase regulator activity	178/3991	490/18639	0.363265306122449	1.69654273134962	1.32381468315716e-14	3.53458520402962e-12
GO:0030695	GTPase regulator activity	177/3991	489/18639	0.361963190184049	1.69046151386632	2.29979831398681e-14	5.11705124862064e-12
GO:0140297	DNA-binding transcription factor binding	171/3991	488/18639	0.350409836065574	1.63650436843554	1.59101504211058e-12	3.03429297316804e-10
GO:0051020	GTPase binding	121/3991	315/18639	0.384126984126984	1.79397215162687	3.3998873376862e-12	5.67356199476384e-10
GO:0031267	small GTPase binding	110/3991	283/18639	0.3886925795053	1.81529466033558	1.38387336155194e-11	2.03002642736294e-09
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	129/3991	349/18639	0.369627507163324	1.72625585217168	1.52061904671382e-11	2.03002642736294e-09
GO:0061659	ubiquitin-like protein ligase activity	133/3991	372/18639	0.35752688172043	1.66974280841571	1.04162198092698e-10	1.26415031321592e-08
GO:0061630	ubiquitin protein ligase activity	127/3991	353/18639	0.359773371104816	1.6802344936163	1.72056307972004e-10	1.91412642618854e-08
GO:0003713	transcription coactivator activity	99/3991	256/18639	0.38671875	1.80607636713856	2.00343122147203e-10	2.05736975435782e-08
GO:0005096	GTPase activator activity	102/3991	271/18639	0.376383763837638	1.75780931450006	6.3494548638254e-10	6.05465874514779e-08
GO:0045296	cadherin binding	119/3991	334/18639	0.356287425149701	1.66395422635061	1.2637175255117e-09	1.12470859770541e-07
GO:0035091	phosphatidylinositol binding	104/3991	284/18639	0.366197183098592	1.71023535348901	2.52672493217848e-09	2.10823611528642e-07
GO:0016922	nuclear receptor binding	59/3991	137/18639	0.430656934306569	2.01127902744679	9.46517653820812e-09	7.43294745794579e-07
GO:0044389	ubiquitin-like protein ligase binding	112/3991	322/18639	0.347826086956522	1.62443759328053	1.76934489512812e-08	1.31226413055336e-06
GO:0005085	guanyl-nucleotide exchange factor activity	86/3991	230/18639	0.373913043478261	1.74627041277657	1.94842564921051e-08	1.36902539036633e-06
GO:0061631	ubiquitin conjugating enzyme activity	23/3991	35/18639	0.657142857142857	3.06902673873358	2.0758757487843e-08	1.38564706231352e-06
GO:0004674	protein serine/threonine kinase activity	139/3991	433/18639	0.321016166281755	1.49922834460677	1.10405783907824e-07	7.01865340556881e-06
GO:0003714	transcription corepressor activity	76/3991	204/18639	0.372549019607843	1.73990006927351	1.51258437520903e-07	9.17863700410935e-06
GO:0106310	protein serine kinase activity	119/3991	361/18639	0.329639889196676	1.53950335623574	1.88678581172486e-07	1.09515611245769e-05
GO:0031625	ubiquitin protein ligase binding	103/3991	302/18639	0.341059602649007	1.59283636526556	1.97387128819953e-07	1.09796590406099e-05
GO:0043130	ubiquitin binding	44/3991	100/18639	0.44	2.05491355549987	3.3349969677868e-07	1.78088838079815e-05
GO:0000149	SNARE binding	45/3991	106/18639	0.424528301886792	1.9826567323648	8.47269462579978e-07	4.35040281747796e-05
GO:0032182	ubiquitin-like protein binding	49/3991	120/18639	0.408333333333333	1.90702204961163	1.1318871844939e-06	5.59655330110872e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	23/3991	41/18639	0.560975609756098	2.61990087452867	1.28959946743846e-06	6.14862603225122e-05
GO:0001217	DNA-binding transcription repressor activity	93/3991	278/18639	0.334532374100719	1.56235252339346	1.95595689153068e-06	9.00414637997744e-05
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	90/3991	268/18639	0.335820895522388	1.56837025097514	2.37226061695836e-06	0.000105565597454647
GO:0005543	phospholipid binding	149/3991	497/18639	0.299798792756539	1.4001377344498	3.5482168276633e-06	0.00015280224080421
GO:0140030	modification-dependent protein binding	63/3991	173/18639	0.364161849710983	1.70072982128865	4.0701315694834e-06	0.000169800801414385
GO:0001221	transcription coregulator binding	45/3991	115/18639	0.391304347826087	1.8274922924406	1.15187192842616e-05	0.000465984552863308
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	143/3991	484/18639	0.295454545454545	1.37984897838318	1.28004035540911e-05	0.000502604080726811
GO:0019902	phosphatase binding	66/3991	190/18639	0.347368421052632	1.62230017539464	1.48020998585262e-05	0.000564594380318073
GO:0001216	DNA-binding transcription activator activity	144/3991	491/18639	0.293279022403259	1.3696887242732	1.81118862765981e-05	0.000671649116090512
GO:0140767	enzyme-substrate adaptor activity	51/3991	139/18639	0.366906474820144	1.71354792888315	2.55563024714665e-05	0.000922099021605615
GO:0005484	SNAP receptor activity	19/3991	36/18639	0.527777777777778	2.46485843147081	3.46900714479167e-05	0.00120326739167168
GO:0046332	SMAD binding	33/3991	79/18639	0.417721518987342	1.9508672995252	3.51516316668132e-05	0.00120326739167168
GO:0036408	histone H3K14 acetyltransferase activity	16/3991	28/18639	0.571428571428571	2.66871890324659	3.99218578269644e-05	0.00129230772647469
GO:0046966	nuclear thyroid hormone receptor binding	16/3991	28/18639	0.571428571428571	2.66871890324659	3.99218578269644e-05	0.00129230772647469
GO:0032266	phosphatidylinositol-3-phosphate binding	23/3991	48/18639	0.479166666666667	2.23783199699323	4.06568722935859e-05	0.00129230772647469
GO:0010484	histone H3 acetyltransferase activity	16/3991	29/18639	0.551724137931034	2.57669411347947	7.13709087739741e-05	0.00221581774914548
GO:1901981	phosphatidylinositol phosphate binding	62/3991	185/18639	0.335135135135135	1.56516757298516	8.81417086606833e-05	0.00267429956959119
GO:0140857	histone H3T45 kinase activity	78/3991	246/18639	0.317073170731707	1.48081353777707	0.000100049991898712	0.00293066738747497
GO:0003779	actin binding	128/3991	443/18639	0.288939051918736	1.34941994204794	0.000106574958784921	0.00293066738747497
GO:0035402	histone H3T11 kinase activity	78/3991	247/18639	0.315789473684211	1.47481834126785	0.000115978370402291	0.00293066738747497
GO:0043995	histone H4K5 acetyltransferase activity	16/3991	30/18639	0.533333333333333	2.49080430969682	0.000122600850271153	0.00293066738747497
GO:0043996	histone H4K8 acetyltransferase activity	16/3991	30/18639	0.533333333333333	2.49080430969682	0.000122600850271153	0.00293066738747497
GO:0043997	histone H4K12 acetyltransferase activity	16/3991	30/18639	0.533333333333333	2.49080430969682	0.000122600850271153	0.00293066738747497
GO:0004679	AMP-activated protein kinase activity	78/3991	248/18639	0.314516129032258	1.46887149311758	0.000134197566443818	0.00293066738747497
GO:0017124	SH3 domain binding	42/3991	115/18639	0.365217391304348	1.70565947294456	0.00014300267956805	0.00293066738747497
GO:0004676	3-phosphoinositide-dependent protein kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0004711	ribosomal protein S6 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0035175	histone H3S10 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0035979	histone H2AXS139 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0044022	histone H3S28 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0044023	histone H4S1 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0044024	histone H2AS1 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0044025	histone H2BS14 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0072354	histone H3T3 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0072371	histone H2AS121 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0072518	Rho-dependent protein serine/threonine kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0140823	histone H2BS36 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0140855	histone H3S57 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0140995	histone H2A kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0140997	histone H4 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0140998	histone H2B kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:1990244	histone H2AT120 kinase activity	77/3991	245/18639	0.314285714285714	1.46779539678562	0.000151472696431291	0.00293066738747497
GO:0004677	DNA-dependent protein kinase activity	77/3991	246/18639	0.313008130081301	1.46182874883121	0.000174901976011222	0.00333563054249973
GO:0035173	histone kinase activity	106/3991	360/18639	0.294444444444444	1.37513154597845	0.000185078986675992	0.00348000629876689
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	76/3991	243/18639	0.312757201646091	1.460656848279	0.000197359077046936	0.00365936622024526
GO:0035403	histone H3T6 kinase activity	77/3991	247/18639	0.311740890688259	1.4559104138157	0.000201590903257618	0.00368662816231397
GO:0140996	histone H3 kinase activity	105/3991	357/18639	0.294117647058824	1.37360531784751	0.000207192970436371	0.00373787318287236
GO:0004712	protein serine/threonine/tyrosine kinase activity	20/3991	43/18639	0.465116279069767	2.17221306078211	0.000213311939566915	0.00379695252429108
GO:0141003	histone H2AX kinase activity	104/3991	354/18639	0.293785310734463	1.37205322144316	0.000231915538124334	0.00407377951836824
GO:0044013	histone H2B acetyltransferase activity	13/3991	23/18639	0.565217391304348	2.63971108908087	0.000249313356800746	0.00432251079648046
GO:0034212	protein N-acetyltransferase activity	23/3991	53/18639	0.433962264150943	2.0267157708618	0.000266070660593017	0.00449625736571743
GO:0140296	general transcription initiation factor binding	23/3991	53/18639	0.433962264150943	2.0267157708618	0.000266070660593017	0.00449625736571743
GO:0005160	transforming growth factor beta receptor binding	14/3991	26/18639	0.538461538461538	2.51475435113621	0.000285965774862124	0.00471313962272759
GO:0052742	phosphatidylinositol kinase activity	14/3991	26/18639	0.538461538461538	2.51475435113621	0.000285965774862124	0.00471313962272759
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	43/3991	122/18639	0.352459016393443	1.64607456942054	0.000297309251717382	0.00480923758159165
GO:0061733	protein-lysine-acetyltransferase activity	21/3991	47/18639	0.446808510638298	2.08671105732579	0.000299001287844275	0.00480923758159165
GO:0010485	histone H4 acetyltransferase activity	17/3991	35/18639	0.485714285714286	2.2684110677596	0.000331873597254414	0.00527441967065051
GO:0005114	type II transforming growth factor beta receptor binding	8/3991	11/18639	0.727272727272727	3.39655133140475	0.000386064771170515	0.00599298220363533
GO:0032050	clathrin heavy chain binding	8/3991	11/18639	0.727272727272727	3.39655133140475	0.000386064771170515	0.00599298220363533
GO:0035035	histone acetyltransferase binding	13/3991	24/18639	0.541666666666667	2.52972312703583	0.000437586796419334	0.006648210316258
GO:0005024	transforming growth factor beta receptor activity	10/3991	16/18639	0.625	2.91891130042596	0.000443214021083867	0.006648210316258
GO:0034450	ubiquitin-ubiquitin ligase activity	10/3991	16/18639	0.625	2.91891130042596	0.000443214021083867	0.006648210316258
GO:0046915	transition metal ion transmembrane transporter activity	20/3991	45/18639	0.444444444444444	2.07567025808068	0.000450756365634302	0.00668621942357547
GO:0004402	histone acetyltransferase activity	19/3991	42/18639	0.452380952380952	2.11273579840355	0.000473556567667093	0.0068834844332775
GO:0031490	chromatin DNA binding	44/3991	128/18639	0.34375	1.60540121523428	0.000474367466562944	0.0068834844332775
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	31/3991	83/18639	0.373493975903614	1.74431325904973	0.000651392200848549	0.00852605998068217
GO:0032931	histone H3K56 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0043992	histone H3K9 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0043993	histone H3K18 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0043994	histone H3K23 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0043999	histone H2AK5 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0044012	histone H2AK9 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0044014	histone H2BK5 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0044015	histone H2BK12 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0044016	histone H3K4 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0044017	histone H3K27 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0044018	histone H3K36 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0140908	histone H3K122 acetyltransferase activity	12/3991	22/18639	0.545454545454545	2.54741349855356	0.000670588987244665	0.00852605998068217
GO:0042974	nuclear retinoic acid receptor binding	13/3991	25/18639	0.52	2.4285342019544	0.000733666123381171	0.00915368481040994
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	13/3991	25/18639	0.52	2.4285342019544	0.000733666123381171	0.00915368481040994
GO:0070273	phosphatidylinositol-4-phosphate binding	15/3991	31/18639	0.483870967741935	2.25980229710397	0.000777717708611618	0.00961345500922694
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	24/3991	60/18639	0.4	1.86810323227261	0.000838315127011305	0.0102674375647715
GO:0008429	phosphatidylethanolamine binding	10/3991	17/18639	0.588235294117647	2.74721063569502	0.000869944458862613	0.0105579622961963
GO:0001223	transcription coactivator binding	19/3991	44/18639	0.431818181818182	2.01670235302157	0.000958259341923564	0.0115250110042158
GO:0019207	kinase regulator activity	84/3991	287/18639	0.292682926829268	1.36690480410191	0.000991495782426202	0.0118182756208837
GO:0003925	G protein activity	22/3991	54/18639	0.407407407407407	1.90269773657396	0.00101862435895169	0.0120341904354027
GO:0019903	protein phosphatase binding	47/3991	144/18639	0.326388888888889	1.524320345778	0.00112549801649316	0.0130066104054855
GO:0019955	cytokine binding	47/3991	144/18639	0.326388888888889	1.524320345778	0.00112549801649316	0.0130066104054855
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	12/3991	23/18639	0.521739130434783	2.4366563899208	0.0011301624022744	0.0130066104054855
GO:0034237	protein kinase A regulatory subunit binding	13/3991	26/18639	0.5	2.33512904034077	0.00118136647190022	0.013365459660905
GO:0050681	nuclear androgen receptor binding	13/3991	26/18639	0.5	2.33512904034077	0.00118136647190022	0.013365459660905
GO:0061578	K63-linked deubiquitinase activity	9/3991	15/18639	0.6	2.80215484840892	0.0013163463446536	0.0147674148748955
GO:0140313	molecular sequestering activity	22/3991	55/18639	0.4	1.86810323227261	0.00135849543110843	0.0151132616710813
GO:0008080	N-acetyltransferase activity	26/3991	69/18639	0.376811594202899	1.75980739272058	0.00147931053811409	0.0163213187469612
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	10/3991	18/18639	0.555555555555556	2.59458782260085	0.00158289101248075	0.017180158550096
GO:0030228	lipoprotein particle receptor activity	10/3991	18/18639	0.555555555555556	2.59458782260085	0.00158289101248075	0.017180158550096
GO:0071889	14-3-3 protein binding	15/3991	33/18639	0.454545454545455	2.12284458212797	0.00173358897792945	0.0184201146586169
GO:0010314	phosphatidylinositol-5-phosphate binding	11/3991	21/18639	0.523809523809524	2.44632566130938	0.00174544806608996	0.0184201146586169
GO:0051010	microtubule plus-end binding	11/3991	21/18639	0.523809523809524	2.44632566130938	0.00174544806608996	0.0184201146586169
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	42/3991	128/18639	0.328125	1.53242843272363	0.00178613085715381	0.0184201146586169
GO:0032452	histone demethylase activity	14/3991	30/18639	0.466666666666667	2.17945377098472	0.00180054014292567	0.0184201146586169
GO:0043998	histone H2A acetyltransferase activity	12/3991	24/18639	0.5	2.33512904034077	0.00182273800812946	0.0184201146586169
GO:0050431	transforming growth factor beta binding	12/3991	24/18639	0.5	2.33512904034077	0.00182273800812946	0.0184201146586169
GO:0140033	acetylation-dependent protein binding	12/3991	24/18639	0.5	2.33512904034077	0.00182273800812946	0.0184201146586169
GO:0005385	zinc ion transmembrane transporter activity	13/3991	27/18639	0.481481481481481	2.2486427795874	0.0018351125465139	0.0184201146586169
GO:0023026	MHC class II protein complex binding	13/3991	27/18639	0.481481481481481	2.2486427795874	0.0018351125465139	0.0184201146586169
GO:0070123	transforming growth factor beta receptor activity, type III	8/3991	13/18639	0.615384615384615	2.8740049727271	0.00198539929302632	0.0192498868869343
GO:0033192	calmodulin-dependent protein phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0140791	histone H2AXS140 phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:1990439	MAP kinase serine/threonine phosphatase activity	29/3991	81/18639	0.358024691358025	1.67206770789833	0.00204755351156904	0.0192498868869343
GO:0035591	signaling adaptor activity	42/3991	129/18639	0.325581395348837	1.52054914254748	0.00210912782958816	0.0196901094580433
GO:0032451	demethylase activity	17/3991	40/18639	0.425	1.98485968428965	0.00215686843922803	0.0199959678220098
GO:0016407	acetyltransferase activity	33/3991	96/18639	0.34375	1.60540121523428	0.00227934545592511	0.020985697818345
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	29/3991	82/18639	0.353658536585366	1.65167663828981	0.00252996553564337	0.0229762176196183
GO:0033549	MAP kinase phosphatase activity	29/3991	82/18639	0.353658536585366	1.65167663828981	0.00252996553564337	0.0229762176196183
GO:0019003	GDP binding	27/3991	75/18639	0.36	1.68129290904535	0.0026226716797368	0.0236572073814096
GO:0140457	protein demethylase activity	14/3991	31/18639	0.451612903225806	2.10914881063037	0.00264286450059608	0.0236793564315152
GO:1990841	promoter-specific chromatin binding	25/3991	68/18639	0.367647058823529	1.71700664730939	0.00267808345712464	0.0236968335850501
GO:0019905	syntaxin binding	23/3991	61/18639	0.377049180327869	1.76091698124058	0.0026803160084963	0.0236968335850501
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	13/3991	28/18639	0.464285714285714	2.16833410888785	0.00276034659447294	0.023928978594944
GO:0097718	disordered domain specific binding	13/3991	28/18639	0.464285714285714	2.16833410888785	0.00276034659447294	0.023928978594944
GO:0141052	histone H3 demethylase activity	13/3991	28/18639	0.464285714285714	2.16833410888785	0.00276034659447294	0.023928978594944
GO:0042826	histone deacetylase binding	41/3991	127/18639	0.322834645669291	1.50772111266097	0.00281495351386999	0.0241353207595419
GO:0046972	histone H4K16 acetyltransferase activity	11/3991	22/18639	0.5	2.33512904034077	0.00282030714493524	0.0241353207595419
GO:0001727	lipid kinase activity	17/3991	41/18639	0.414634146341463	1.93644847247771	0.0029588698253858	0.0249911351578439
GO:0016176	superoxide-generating NADPH oxidase activator activity	7/3991	11/18639	0.636363636363636	2.97198241497916	0.00297647227722636	0.0249911351578439
GO:0048185	activin binding	7/3991	11/18639	0.636363636363636	2.97198241497916	0.00297647227722636	0.0249911351578439
GO:0140034	methylation-dependent protein binding	27/3991	76/18639	0.355263157894737	1.65917063392633	0.00325134447139644	0.027128405433214
GO:0016757	glycosyltransferase activity	76/3991	267/18639	0.284644194756554	1.32936185068089	0.00372762430655719	0.0308034669109894
GO:0019209	kinase activator activity	46/3991	148/18639	0.310810810810811	1.45156670075237	0.0037379487936931	0.0308034669109894
GO:0017018	myosin phosphatase activity	29/3991	84/18639	0.345238095238095	1.61235100404482	0.00378993124133696	0.0309633191551775
GO:0042393	histone binding	71/3991	247/18639	0.287449392712551	1.34246284910279	0.00380373358910046	0.0309633191551775
GO:0031593	polyubiquitin modification-dependent protein binding	22/3991	59/18639	0.372881355932203	1.74145216567786	0.00384737388062357	0.0311287523068634
GO:0004722	protein serine/threonine phosphatase activity	34/3991	103/18639	0.330097087378641	1.54163858973954	0.00416095316681286	0.0334630872150311
GO:0016805	dipeptidase activity	9/3991	17/18639	0.529411764705882	2.47248957212552	0.00420407070735006	0.0335752293052491
GO:0097602	cullin family protein binding	12/3991	26/18639	0.461538461538462	2.15550372954532	0.00423946541303729	0.0335752293052491
GO:0001222	transcription corepressor binding	19/3991	49/18639	0.387755102040816	1.81091639863161	0.00425034738021505	0.0335752293052491
GO:0001618	virus receptor activity	28/3991	81/18639	0.345679012345679	1.61441020072942	0.00430660027986869	0.0337192177301721
GO:0019888	protein phosphatase regulator activity	35/3991	107/18639	0.327102803738318	1.52765451237246	0.00434132830557676	0.0337192177301721
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	11/3991	23/18639	0.478260869565217	2.23360169076073	0.00436960649237436	0.0337192177301721
GO:0070577	lysine-acetylated histone binding	11/3991	23/18639	0.478260869565217	2.23360169076073	0.00436960649237436	0.0337192177301721
GO:0030276	clathrin binding	18/3991	46/18639	0.391304347826087	1.8274922924406	0.00475393114299657	0.0364741268729909
GO:0003924	GTPase activity	91/3991	331/18639	0.274924471299094	1.28396823366169	0.00482997033146529	0.0368457736714638
GO:0051018	protein kinase A binding	20/3991	53/18639	0.377358490566038	1.76236153987982	0.00488693335895776	0.0370685001943671
GO:0140272	exogenous protein binding	28/3991	82/18639	0.341463414634146	1.59472227145223	0.0052278182953929	0.0394301549398278
GO:0005025	transforming growth factor beta receptor activity, type I	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0005026	transforming growth factor beta receptor activity, type II	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0005078	MAP-kinase scaffold activity	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0016361	activin receptor activity, type I	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0016362	activin receptor activity, type II	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0017002	activin receptor activity	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/3991	12/18639	0.583333333333333	2.72431721373089	0.0058274223806274	0.0416021865141047
GO:0030331	nuclear estrogen receptor binding	16/3991	40/18639	0.4	1.86810323227261	0.00590942788102638	0.0419632245806927
GO:0008234	cysteine-type peptidase activity	55/3991	187/18639	0.294117647058824	1.37360531784751	0.00603239178478733	0.04260975149572
GO:0019838	growth factor binding	42/3991	136/18639	0.308823529411765	1.44228558373989	0.0061293107339146	0.0430664727882947
GO:0019208	phosphatase regulator activity	37/3991	117/18639	0.316239316239316	1.47691922209587	0.00638236961254576	0.044609756192401
GO:0023023	MHC protein complex binding	15/3991	37/18639	0.405405405405405	1.89334787054657	0.0065601223047775	0.0454140348102258
GO:0005041	low-density lipoprotein particle receptor activity	8/3991	15/18639	0.533333333333333	2.49080430969682	0.00656547469541092	0.0454140348102258
GO:0034185	apolipoprotein binding	9/3991	18/18639	0.5	2.33512904034077	0.00682525040221939	0.0469675736441386
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	16/3991	41/18639	0.390243902439024	1.82253973880255	0.00779778503663633	0.0533848360200487
GO:0019887	protein kinase regulator activity	71/3991	255/18639	0.27843137254902	1.30034636756231	0.00859782222161325	0.0585616972747637
GO:0005381	iron ion transmembrane transporter activity	6/3991	10/18639	0.6	2.80215484840892	0.00903413151369887	0.0597057701524158
GO:0008140	cAMP response element binding protein binding	6/3991	10/18639	0.6	2.80215484840892	0.00903413151369887	0.0597057701524158
GO:0008239	dipeptidyl-peptidase activity	6/3991	10/18639	0.6	2.80215484840892	0.00903413151369887	0.0597057701524158
GO:0016303	1-phosphatidylinositol-3-kinase activity	6/3991	10/18639	0.6	2.80215484840892	0.00903413151369887	0.0597057701524158
GO:0032395	MHC class II receptor activity	6/3991	10/18639	0.6	2.80215484840892	0.00903413151369887	0.0597057701524158
GO:0042975	peroxisome proliferator activated receptor binding	6/3991	10/18639	0.6	2.80215484840892	0.00903413151369887	0.0597057701524158
GO:0035064	methylated histone binding	25/3991	74/18639	0.337837837837838	1.57778989212214	0.00932218298206489	0.0613059816800819
GO:0017025	TBP-class protein binding	11/3991	25/18639	0.44	2.05491355549987	0.00942913142439409	0.0617053453508142
GO:0004721	phosphoprotein phosphatase activity	51/3991	175/18639	0.291428571428571	1.36104664065576	0.00959573215633507	0.0624892801400357
GO:0051213	dioxygenase activity	30/3991	93/18639	0.32258064516129	1.50653486473598	0.00974543448275938	0.0628509905047526
GO:0051219	phosphoprotein binding	30/3991	93/18639	0.32258064516129	1.50653486473598	0.00974543448275938	0.0628509905047526
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	7/3991	13/18639	0.538461538461538	2.51475435113621	0.0103097826494953	0.0661709607551742
GO:0140789	histone phosphatase activity	41/3991	136/18639	0.301470588235294	1.4079454507937	0.0104234105608076	0.0665801583668812
GO:0042277	peptide binding	69/3991	249/18639	0.27710843373494	1.29416790187561	0.0106061492103515	0.0669985942966306
GO:0001098	basal transcription machinery binding	21/3991	60/18639	0.35	1.63459032823854	0.0106394771467309	0.0669985942966306
GO:0001099	basal RNA polymerase II transcription machinery binding	21/3991	60/18639	0.35	1.63459032823854	0.0106394771467309	0.0669985942966306
GO:0004707	MAP kinase activity	8/3991	16/18639	0.5	2.33512904034077	0.0106920043444358	0.0670132666658297
GO:0043236	laminin binding	12/3991	29/18639	0.413793103448276	1.9325205851096	0.012019471891147	0.0746325347659591
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	12/3991	29/18639	0.413793103448276	1.9325205851096	0.012019471891147	0.0746325347659591
GO:0001540	amyloid-beta binding	27/3991	83/18639	0.325301204819277	1.51924058046267	0.0122015654196647	0.0754124529409833
GO:0008013	beta-catenin binding	33/3991	106/18639	0.311320754716981	1.45394827040085	0.0123061426797758	0.0757082971313395
GO:0048156	tau protein binding	16/3991	43/18639	0.372093023255814	1.73777044862569	0.013002740009459	0.079626871158843
GO:0043548	phosphatidylinositol 3-kinase binding	11/3991	26/18639	0.423076923076923	1.97587841874988	0.0132348864993891	0.0803116976212927
GO:0070412	R-SMAD binding	11/3991	26/18639	0.423076923076923	1.97587841874988	0.0132348864993891	0.0803116976212927
GO:0038024	cargo receptor activity	22/3991	65/18639	0.338461538461538	1.5807027349999	0.0138413071320209	0.0836115159332487
GO:0016791	phosphatase activity	74/3991	273/18639	0.271062271062271	1.26593076179646	0.0143401629872254	0.0854111893404359
GO:0004860	protein kinase inhibitor activity	27/3991	84/18639	0.321428571428571	1.50115438307621	0.0143968990339451	0.0854111893404359
GO:0140103	catalytic activity, acting on a glycoprotein	10/3991	23/18639	0.434782608695652	2.03054699160067	0.0144470424039105	0.0854111893404359
GO:0043495	protein-membrane adaptor activity	17/3991	47/18639	0.361702127659574	1.68924228450183	0.0144542680096266	0.0854111893404359
GO:0140311	protein sequestering activity	13/3991	33/18639	0.393939393939394	1.83979863784424	0.0144591226898416	0.0854111893404359
GO:0061791	GTPase motor activity	15/3991	40/18639	0.375	1.75134678025558	0.0147428168994343	0.0863230726348453
GO:1990606	membrane scission GTPase motor activity	15/3991	40/18639	0.375	1.75134678025558	0.0147428168994343	0.0863230726348453
GO:0004197	cysteine-type endopeptidase activity	28/3991	88/18639	0.318181818181818	1.48599120748958	0.0148332410448113	0.0864732611127643
GO:0031418	L-ascorbic acid binding	9/3991	20/18639	0.45	2.10161613630669	0.0155710661839377	0.0903798841545951
GO:0008432	JUN kinase binding	6/3991	11/18639	0.545454545454545	2.54741349855356	0.0163033225974659	0.0931128549233168
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	6/3991	11/18639	0.545454545454545	2.54741349855356	0.0163033225974659	0.0931128549233168
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	6/3991	11/18639	0.545454545454545	2.54741349855356	0.0163033225974659	0.0931128549233168
GO:0017110	nucleoside diphosphate phosphatase activity	8/3991	17/18639	0.470588235294118	2.19776850855602	0.0164590564662896	0.0931128549233168
GO:0046965	nuclear retinoid X receptor binding	8/3991	17/18639	0.470588235294118	2.19776850855602	0.0164590564662896	0.0931128549233168
GO:0001046	core promoter sequence-specific DNA binding	16/3991	44/18639	0.363636363636364	1.69827566570238	0.01646039982165	0.0931128549233168
GO:0004705	JUN kinase activity	7/3991	14/18639	0.5	2.33512904034077	0.0168536257239836	0.0937482930896588
GO:0005545	1-phosphatidylinositol binding	7/3991	14/18639	0.5	2.33512904034077	0.0168536257239836	0.0937482930896588
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	7/3991	14/18639	0.5	2.33512904034077	0.0168536257239836	0.0937482930896588
GO:0098821	BMP receptor activity	7/3991	14/18639	0.5	2.33512904034077	0.0168536257239836	0.0937482930896588
GO:0004713	protein tyrosine kinase activity	41/3991	140/18639	0.292857142857143	1.36771843791388	0.0172023589848738	0.0952910757045915
GO:0042625	ATPase-coupled ion transmembrane transporter activity	10/3991	24/18639	0.416666666666667	1.94594086695064	0.0201058947952993	0.109303378873131
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	10/3991	24/18639	0.416666666666667	1.94594086695064	0.0201058947952993	0.109303378873131
GO:0046961	proton-transporting ATPase activity, rotational mechanism	10/3991	24/18639	0.416666666666667	1.94594086695064	0.0201058947952993	0.109303378873131
GO:0050699	WW domain binding	10/3991	24/18639	0.416666666666667	1.94594086695064	0.0201058947952993	0.109303378873131
GO:0019210	kinase inhibitor activity	28/3991	90/18639	0.311111111111111	1.45296918065648	0.0201412967811163	0.109303378873131
GO:0016763	pentosyltransferase activity	17/3991	49/18639	0.346938775510204	1.62029361982829	0.0222216904255128	0.120105087927367
GO:0042578	phosphoric ester hydrolase activity	94/3991	363/18639	0.258953168044077	1.20937812557593	0.0224999004274948	0.121118415607684
GO:0004520	DNA endonuclease activity	15/3991	42/18639	0.357142857142857	1.66794931452912	0.023533143197717	0.126171671361254
GO:0016854	racemase and epimerase activity	8/3991	18/18639	0.444444444444444	2.07567025808068	0.0241661013175459	0.128340508239444
GO:0050811	GABA receptor binding	8/3991	18/18639	0.444444444444444	2.07567025808068	0.0241661013175459	0.128340508239444
GO:0140566	histone reader activity	13/3991	35/18639	0.371428571428571	1.73466728711028	0.0243395056334996	0.128340508239444
GO:0005518	collagen binding	23/3991	72/18639	0.319444444444444	1.49188799799549	0.0243957448062443	0.128340508239444
GO:0030295	protein kinase activator activity	40/3991	139/18639	0.287769784172662	1.34395915990835	0.0244183438897519	0.128340508239444
GO:0019783	ubiquitin-like protein peptidase activity	37/3991	127/18639	0.291338582677165	1.36062636996234	0.0245784102579021	0.128675206644311
GO:0030291	protein serine/threonine kinase inhibitor activity	16/3991	46/18639	0.347826086956522	1.62443759328053	0.0254494030220586	0.132714660290813
GO:0042809	nuclear vitamin D receptor binding	7/3991	15/18639	0.466666666666667	2.17945377098472	0.0258557578739847	0.134309092458247
GO:0035014	phosphatidylinositol 3-kinase regulator activity	6/3991	12/18639	0.5	2.33512904034077	0.0267792228143044	0.137501009450371
GO:0035259	nuclear glucocorticoid receptor binding	6/3991	12/18639	0.5	2.33512904034077	0.0267792228143044	0.137501009450371
GO:0035497	cAMP response element binding	6/3991	12/18639	0.5	2.33512904034077	0.0267792228143044	0.137501009450371
GO:0004896	cytokine receptor activity	29/3991	96/18639	0.302083333333333	1.41080712853921	0.027111553765832	0.138674039376957
GO:0004709	MAP kinase kinase kinase activity	10/3991	25/18639	0.4	1.86810323227261	0.0272237370425695	0.138716370045154
GO:0002020	protease binding	39/3991	136/18639	0.286764705882353	1.33926518490132	0.0274355792563605	0.139264252118788
GO:0071813	lipoprotein particle binding	12/3991	32/18639	0.375	1.75134678025558	0.0277324999205765	0.139709009033848
GO:0071814	protein-lipid complex binding	12/3991	32/18639	0.375	1.75134678025558	0.0277324999205765	0.139709009033848
GO:0061980	regulatory RNA binding	19/3991	58/18639	0.327586206896552	1.52991212987843	0.0298583865150179	0.149853180441913
GO:1990782	protein tyrosine kinase binding	34/3991	117/18639	0.290598290598291	1.35716901489891	0.0312596469255536	0.156298234627768
GO:1990380	K48-linked deubiquitinase activity	8/3991	19/18639	0.421052631578947	1.9664244550238	0.0340800450349929	0.169764403439237
GO:0005525	GTP binding	96/3991	378/18639	0.253968253968254	1.18609729033182	0.0344209841246942	0.170825330135564
GO:0019239	deaminase activity	12/3991	33/18639	0.363636363636364	1.69827566570238	0.0353172869095679	0.174624363052864
GO:0001786	phosphatidylserine binding	19/3991	59/18639	0.322033898305085	1.5039814158127	0.0354567706875811	0.174667117593804
GO:0019205	nucleobase-containing compound kinase activity	15/3991	44/18639	0.340909090909091	1.59213343659598	0.0357506534467298	0.175467361585971
GO:0051015	actin filament binding	56/3991	209/18639	0.267942583732057	1.25136101683333	0.0366867983832186	0.179402475610245
GO:0070411	I-SMAD binding	7/3991	16/18639	0.4375	2.04323791029817	0.0376497883969673	0.183439662445078
GO:1902936	phosphatidylinositol bisphosphate binding	32/3991	111/18639	0.288288288288288	1.34638070794423	0.0397384766362596	0.192912241125115
GO:0031624	ubiquitin conjugating enzyme binding	11/3991	30/18639	0.366666666666667	1.71242796291656	0.040499086902279	0.195185130016399
GO:0051721	protein phosphatase 2A binding	11/3991	30/18639	0.366666666666667	1.71242796291656	0.040499086902279	0.195185130016399
GO:0004536	DNA nuclease activity	20/3991	64/18639	0.3125	1.45945565021298	0.0427158444525753	0.200751691145397
GO:0004382	GDP phosphatase activity	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0004445	inositol-polyphosphate 5-phosphatase activity	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0005131	growth hormone receptor binding	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0045322	unmethylated CpG binding	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0070513	death domain binding	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:1905394	retromer complex binding	5/3991	10/18639	0.5	2.33512904034077	0.0430074784026842	0.200751691145397
GO:0042605	peptide antigen binding	15/3991	45/18639	0.333333333333333	1.55675269356051	0.0433334503745341	0.201568488675969
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	12/3991	34/18639	0.352941176470588	1.64832638141701	0.0442613919795433	0.205169994071842
GO:0043022	ribosome binding	32/3991	112/18639	0.285714285714286	1.3343594516233	0.0445600496766273	0.20583967584186
GO:0004843	cysteine-type deubiquitinase activity	31/3991	108/18639	0.287037037037037	1.34053704167711	0.0447983104742111	0.206226705114041
GO:0019001	guanyl nucleotide binding	100/3991	400/18639	0.25	1.16756452017038	0.0457878910147303	0.209338474331044
GO:0032561	guanyl ribonucleotide binding	100/3991	400/18639	0.25	1.16756452017038	0.0457878910147303	0.209338474331044
GO:0005044	scavenger receptor activity	10/3991	27/18639	0.37037037037037	1.72972521506723	0.0464784887569922	0.211770588705067
GO:1901505	carbohydrate derivative transmembrane transporter activity	17/3991	53/18639	0.320754716981132	1.49800730889785	0.0466834241109216	0.211980854381226
GO:0015026	coreceptor activity	19/3991	61/18639	0.311475409836066	1.45467054972048	0.0489047834092856	0.221314867292869
GO:0035198	miRNA binding	14/3991	42/18639	0.333333333333333	1.55675269356051	0.0499125805103046	0.22435452855642
GO:0043175	RNA polymerase core enzyme binding	14/3991	42/18639	0.333333333333333	1.55675269356051	0.0499125805103046	0.22435452855642
GO:0008327	methyl-CpG binding	11/3991	31/18639	0.354838709677419	1.65718835120958	0.0510030146943469	0.228486659788433
GO:0004550	nucleoside diphosphate kinase activity	7/3991	17/18639	0.411764705882353	1.92304744498651	0.0524833007484415	0.23277477242249
GO:0031489	myosin V binding	7/3991	17/18639	0.411764705882353	1.92304744498651	0.0524833007484415	0.23277477242249
GO:0070403	NAD+ binding	7/3991	17/18639	0.411764705882353	1.92304744498651	0.0524833007484415	0.23277477242249
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/3991	24/18639	0.375	1.75134678025558	0.0533802879226059	0.235969153565162
GO:0005154	epidermal growth factor receptor binding	12/3991	35/18639	0.342857142857143	1.60123134194795	0.0546554196383488	0.240808532069953
GO:0140463	chromatin-protein adaptor activity	17/3991	54/18639	0.314814814814815	1.47026643280715	0.0549958358653299	0.241511318684919
GO:0016410	N-acyltransferase activity	27/3991	94/18639	0.287234042553192	1.34145710828087	0.0576307520869468	0.252252636183849
GO:0008474	palmitoyl-(protein) hydrolase activity	6/3991	14/18639	0.428571428571429	2.00153917743494	0.0589275808792586	0.255416624914968
GO:0032454	histone H3K9 demethylase activity	6/3991	14/18639	0.428571428571429	2.00153917743494	0.0589275808792586	0.255416624914968
GO:0098599	palmitoyl hydrolase activity	6/3991	14/18639	0.428571428571429	2.00153917743494	0.0589275808792586	0.255416624914968
GO:0043021	ribonucleoprotein complex binding	47/3991	177/18639	0.265536723163842	1.24012502707363	0.0592933169924623	0.256170155938308
GO:0008375	acetylglucosaminyltransferase activity	14/3991	43/18639	0.325581395348837	1.52054914254748	0.0599241011470041	0.258060242036292
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	8/3991	21/18639	0.380952380952381	1.77914593549773	0.0613419434631005	0.262472738856536
GO:0005123	death receptor binding	8/3991	21/18639	0.380952380952381	1.77914593549773	0.0613419434631005	0.262472738856536
GO:0101005	deubiquitinase activity	32/3991	115/18639	0.278260869565217	1.29955007462443	0.0616170547838536	0.262807565931133
GO:0005178	integrin binding	43/3991	161/18639	0.267080745341615	1.24733600912612	0.063408929635769	0.269588920585196
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	59/3991	229/18639	0.25764192139738	1.20325426532843	0.0647297308846539	0.269731755420708
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0002162	dystroglycan binding	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0019206	nucleoside kinase activity	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0034713	type I transforming growth factor beta receptor binding	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0042608	T cell receptor binding	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0097493	structural molecule activity conferring elasticity	5/3991	11/18639	0.454545454545455	2.12284458212797	0.0652609415736994	0.269731755420708
GO:0050840	extracellular matrix binding	20/3991	67/18639	0.298507462686567	1.39410688975568	0.0659723287829931	0.271830428781777
GO:0000993	RNA polymerase II complex binding	12/3991	36/18639	0.333333333333333	1.55675269356051	0.0665714119604548	0.272616058181617
GO:0044390	ubiquitin-like protein conjugating enzyme binding	12/3991	36/18639	0.333333333333333	1.55675269356051	0.0665714119604548	0.272616058181617
GO:0008483	transaminase activity	9/3991	25/18639	0.36	1.68129290904535	0.0680933477926261	0.277148229582792
GO:0015296	monoatomic anion:monoatomic cation symporter activity	9/3991	25/18639	0.36	1.68129290904535	0.0680933477926261	0.277148229582792
GO:0000287	magnesium ion binding	59/3991	230/18639	0.256521739130435	1.19802272504439	0.0694529565625776	0.281822787267602
GO:0004706	JUN kinase kinase kinase activity	7/3991	18/18639	0.388888888888889	1.8162114758206	0.0705033367499206	0.283499863135976
GO:0017075	syntaxin-1 binding	7/3991	18/18639	0.388888888888889	1.8162114758206	0.0705033367499206	0.283499863135976
GO:0098641	cadherin binding involved in cell-cell adhesion	7/3991	18/18639	0.388888888888889	1.8162114758206	0.0705033367499206	0.283499863135976
GO:0016790	thiolester hydrolase activity	14/3991	44/18639	0.318181818181818	1.48599120748958	0.0712050434071324	0.285461660506071
GO:0035250	UDP-galactosyltransferase activity	10/3991	29/18639	0.344827586206897	1.61043382092467	0.0732325026742952	0.292710751707138
GO:0017022	myosin binding	22/3991	76/18639	0.289473684210526	1.35191681282886	0.0749773729424459	0.298790426501986
GO:0016758	hexosyltransferase activity	51/3991	197/18639	0.258883248730964	1.20905158433887	0.0754329894154576	0.299711431159631
GO:0140416	transcription regulator inhibitor activity	11/3991	33/18639	0.333333333333333	1.55675269356051	0.0771298544804134	0.305544082288878
GO:0015377	chloride:monoatomic cation symporter activity	8/3991	22/18639	0.363636363636364	1.69827566570238	0.0789371695753487	0.311778465630445
GO:0043394	proteoglycan binding	12/3991	37/18639	0.324324324324324	1.51467829643725	0.0800602922095871	0.315281681710321
GO:0047372	monoacylglycerol lipase activity	6/3991	15/18639	0.4	1.86810323227261	0.0809754628827745	0.317015375215554
GO:0120283	protein serine/threonine kinase binding	6/3991	15/18639	0.4	1.86810323227261	0.0809754628827745	0.317015375215554
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	25/3991	89/18639	0.280898876404494	1.31187024738245	0.0822873075278835	0.320272756704736
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	25/3991	89/18639	0.280898876404494	1.31187024738245	0.0822873075278835	0.320272756704736
GO:0004715	non-membrane spanning protein tyrosine kinase activity	14/3991	45/18639	0.311111111111111	1.45296918065648	0.083792214454112	0.324589887822826
GO:0030971	receptor tyrosine kinase binding	23/3991	81/18639	0.283950617283951	1.32612266488488	0.0838827799991574	0.324589887822826
GO:0060590	ATPase regulator activity	15/3991	49/18639	0.306122448979592	1.42967084102496	0.0848682706956843	0.327407929609745
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/3991	26/18639	0.346153846153846	1.61662779715899	0.0851015367599863	0.327407929609745
GO:0002039	p53 binding	20/3991	69/18639	0.289855072463768	1.35369799440044	0.0855839148675588	0.328317604448825
GO:0004725	protein tyrosine phosphatase activity	27/3991	98/18639	0.275510204081633	1.28670375692246	0.0892620725799213	0.34144661001202
GO:0001968	fibronectin binding	10/3991	30/18639	0.333333333333333	1.55675269356051	0.0895992105603033	0.341756988851443
GO:0140793	histone H2AXY142 phosphatase activity	25/3991	90/18639	0.277777777777778	1.29729391130043	0.0916683736191224	0.342987325573876
GO:0043395	heparan sulfate proteoglycan binding	7/3991	19/18639	0.368421052631579	1.72062139814583	0.0917502569169619	0.342987325573876
GO:0046527	glucosyltransferase activity	7/3991	19/18639	0.368421052631579	1.72062139814583	0.0917502569169619	0.342987325573876
GO:0140036	ubiquitin-modified protein reader activity	7/3991	19/18639	0.368421052631579	1.72062139814583	0.0917502569169619	0.342987325573876
GO:0005247	voltage-gated chloride channel activity	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0008603	cAMP-dependent protein kinase regulator activity	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0035251	UDP-glucosyltransferase activity	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0070008	serine-type exopeptidase activity	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0070410	co-SMAD binding	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0097677	STAT family protein binding	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/3991	12/18639	0.416666666666667	1.94594086695064	0.0927478835446961	0.342987325573876
GO:0042162	telomeric DNA binding	12/3991	38/18639	0.315789473684211	1.47481834126785	0.0951500099150307	0.349931854646187
GO:0042887	amide transmembrane transporter activity	12/3991	38/18639	0.315789473684211	1.47481834126785	0.0951500099150307	0.349931854646187
GO:0008194	UDP-glycosyltransferase activity	38/3991	145/18639	0.262068965517241	1.22392970390275	0.096869563739309	0.355277108769169
GO:0015605	organophosphate ester transmembrane transporter activity	15/3991	50/18639	0.3	1.40107742420446	0.098242676215181	0.358972220858959
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	16/3991	54/18639	0.296296296296296	1.38378017205379	0.0984148560557147	0.358972220858959
GO:0042171	lysophosphatidic acid acyltransferase activity	8/3991	23/18639	0.347826086956522	1.62443759328053	0.0992223850822729	0.359950771969658
GO:0071617	lysophospholipid acyltransferase activity	8/3991	23/18639	0.347826086956522	1.62443759328053	0.0992223850822729	0.359950771969658
GO:0072341	modified amino acid binding	25/3991	91/18639	0.274725274725275	1.28303793425317	0.101725574948908	0.368031551644422
GO:0001671	ATPase activator activity	9/3991	27/18639	0.333333333333333	1.55675269356051	0.104413060761483	0.376606089451986
GO:0030165	PDZ domain binding	23/3991	83/18639	0.27710843373494	1.29416790187561	0.104659819615496	0.376606089451986
GO:0004708	MAP kinase kinase activity	6/3991	16/18639	0.375	1.75134678025558	0.106970867574259	0.379803479286264
GO:0005159	insulin-like growth factor receptor binding	6/3991	16/18639	0.375	1.75134678025558	0.106970867574259	0.379803479286264
GO:0005521	lamin binding	6/3991	16/18639	0.375	1.75134678025558	0.106970867574259	0.379803479286264
GO:0015378	sodium:chloride symporter activity	6/3991	16/18639	0.375	1.75134678025558	0.106970867574259	0.379803479286264
GO:0030275	LRR domain binding	6/3991	16/18639	0.375	1.75134678025558	0.106970867574259	0.379803479286264
GO:0003725	double-stranded RNA binding	21/3991	75/18639	0.28	1.30767226259083	0.107402196932858	0.380323429457201
GO:0045309	protein phosphorylated amino acid binding	17/3991	59/18639	0.288135593220339	1.34566758256926	0.111739576638631	0.393594550956655
GO:0070063	RNA polymerase binding	17/3991	59/18639	0.288135593220339	1.34566758256926	0.111739576638631	0.393594550956655
GO:0005048	signal sequence binding	15/3991	51/18639	0.294117647058824	1.37360531784751	0.112845113428378	0.395785454494336
GO:0001784	phosphotyrosine residue binding	14/3991	47/18639	0.297872340425532	1.39114070488386	0.112954500496136	0.395785454494336
GO:0015095	magnesium ion transmembrane transporter activity	7/3991	20/18639	0.35	1.63459032823854	0.116159199112002	0.40383471566282
GO:0043024	ribosomal small subunit binding	7/3991	20/18639	0.35	1.63459032823854	0.116159199112002	0.40383471566282
GO:0052745	inositol phosphate phosphatase activity	7/3991	20/18639	0.35	1.63459032823854	0.116159199112002	0.40383471566282
GO:0140375	immune receptor activity	40/3991	156/18639	0.256410256410256	1.19750207196962	0.117337751904914	0.40687246439756
GO:0004622	lysophospholipase activity	8/3991	24/18639	0.333333333333333	1.55675269356051	0.122143433662106	0.422439077561948
GO:0004535	poly(A)-specific ribonuclease activity	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0005035	death receptor activity	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0008035	high-density lipoprotein particle binding	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0045159	myosin II binding	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0089720	caspase binding	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0140410	monoatomic cation:bicarbonate symporter activity	5/3991	13/18639	0.384615384615385	1.79625310795444	0.125155382127186	0.425146145393877
GO:0051019	mitogen-activated protein kinase binding	9/3991	28/18639	0.321428571428571	1.50115438307621	0.125984443954645	0.426876225074748
GO:0008378	galactosyltransferase activity	10/3991	32/18639	0.3125	1.45945565021298	0.128335633036152	0.432646641674906
GO:0043425	bHLH transcription factor binding	10/3991	32/18639	0.3125	1.45945565021298	0.128335633036152	0.432646641674906
GO:0016409	palmitoyltransferase activity	11/3991	36/18639	0.305555555555556	1.42702330243047	0.129620065044527	0.435876037366356
GO:0043014	alpha-tubulin binding	13/3991	44/18639	0.295454545454545	1.37984897838318	0.130043265030709	0.436200399035168
GO:0008238	exopeptidase activity	27/3991	102/18639	0.264705882352941	1.23624478606276	0.130707792869971	0.437330585166443
GO:0035401	histone H3Y41 kinase activity	30/3991	115/18639	0.260869565217391	1.2183281949604	0.133928646831357	0.44587217835377
GO:0140801	histone H2AXY142 kinase activity	30/3991	115/18639	0.260869565217391	1.2183281949604	0.133928646831357	0.44587217835377
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/3991	17/18639	0.352941176470588	1.64832638141701	0.136691358570159	0.452811324295687
GO:0030169	low-density lipoprotein particle binding	6/3991	17/18639	0.352941176470588	1.64832638141701	0.136691358570159	0.452811324295687
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/3991	21/18639	0.333333333333333	1.55675269356051	0.143567826936453	0.464989192784608
GO:0008373	sialyltransferase activity	7/3991	21/18639	0.333333333333333	1.55675269356051	0.143567826936453	0.464989192784608
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/3991	21/18639	0.333333333333333	1.55675269356051	0.143567826936453	0.464989192784608
GO:0140312	cargo adaptor activity	7/3991	21/18639	0.333333333333333	1.55675269356051	0.143567826936453	0.464989192784608
GO:0015294	solute:monoatomic cation symporter activity	30/3991	116/18639	0.258620689655172	1.2078253656935	0.14528842416445	0.464989192784608
GO:0004864	protein phosphatase inhibitor activity	15/3991	53/18639	0.283018867924528	1.32177115490987	0.145687520559889	0.464989192784608
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0005031	tumor necrosis factor receptor activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0015279	store-operated calcium channel activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0016868	intramolecular phosphotransferase activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0019911	structural constituent of myelin sheath	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0030957	Tat protein binding	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0043422	protein kinase B binding	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0051864	histone H3K36 demethylase activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0099122	RNA polymerase II C-terminal domain binding	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0140999	histone H3K4 trimethyltransferase activity	4/3991	10/18639	0.4	1.86810323227261	0.146985347831539	0.464989192784608
GO:0000030	mannosyltransferase activity	8/3991	25/18639	0.32	1.49448258581809	0.14757876818892	0.465762779035955
GO:0051861	glycolipid binding	9/3991	29/18639	0.310344827586207	1.4493904388322	0.149722817530802	0.470842353741387
GO:0019213	deacetylase activity	11/3991	37/18639	0.297297297297297	1.38845510506748	0.150587661243925	0.470842353741387
GO:0042805	actinin binding	11/3991	37/18639	0.297297297297297	1.38845510506748	0.150587661243925	0.470842353741387
GO:0030296	protein tyrosine kinase activator activity	10/3991	33/18639	0.303030303030303	1.41522972141865	0.150599015016908	0.470842353741387
GO:0097110	scaffold protein binding	19/3991	70/18639	0.271428571428571	1.26764147904213	0.152685330708007	0.476249804895302
GO:0015631	tubulin binding	91/3991	385/18639	0.236363636363636	1.10387918270654	0.155710638819744	0.484554085837664
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0034236	protein kinase A catalytic subunit binding	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0042813	Wnt receptor activity	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0044548	S100 protein binding	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0046030	inositol trisphosphate phosphatase activity	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0070742	C2H2 zinc finger domain binding	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0071933	Arp2/3 complex binding	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0098847	sequence-specific single stranded DNA binding	5/3991	14/18639	0.357142857142857	1.66794931452912	0.161948605042701	0.494740017693378
GO:0000900	mRNA regulatory element binding translation repressor activity	6/3991	18/18639	0.333333333333333	1.55675269356051	0.169785369480278	0.513976118494719
GO:0015373	monoatomic anion:sodium symporter activity	6/3991	18/18639	0.333333333333333	1.55675269356051	0.169785369480278	0.513976118494719
GO:0070064	proline-rich region binding	6/3991	18/18639	0.333333333333333	1.55675269356051	0.169785369480278	0.513976118494719
GO:1990381	ubiquitin-specific protease binding	6/3991	18/18639	0.333333333333333	1.55675269356051	0.169785369480278	0.513976118494719
GO:0048487	beta-tubulin binding	12/3991	42/18639	0.285714285714286	1.3343594516233	0.171231109667228	0.517179935307125
GO:0004407	histone deacetylase activity	7/3991	22/18639	0.318181818181818	1.48599120748958	0.173728800371635	0.518316932914727
GO:0033558	protein lysine deacetylase activity	7/3991	22/18639	0.318181818181818	1.48599120748958	0.173728800371635	0.518316932914727
GO:0140035	ubiquitin-like protein reader activity	7/3991	22/18639	0.318181818181818	1.48599120748958	0.173728800371635	0.518316932914727
GO:0051427	hormone receptor binding	10/3991	34/18639	0.294117647058824	1.37360531784751	0.174661290466723	0.518316932914727
GO:0052866	phosphatidylinositol phosphate phosphatase activity	10/3991	34/18639	0.294117647058824	1.37360531784751	0.174661290466723	0.518316932914727
GO:0008157	protein phosphatase 1 binding	8/3991	26/18639	0.307692307692308	1.43700248636355	0.17534642660178	0.518316932914727
GO:0050750	low-density lipoprotein particle receptor binding	8/3991	26/18639	0.307692307692308	1.43700248636355	0.17534642660178	0.518316932914727
GO:0015215	nucleotide transmembrane transporter activity	9/3991	30/18639	0.3	1.40107742420446	0.175490077661016	0.518316932914727
GO:0016769	transferase activity, transferring nitrogenous groups	9/3991	30/18639	0.3	1.40107742420446	0.175490077661016	0.518316932914727
GO:0035925	mRNA 3'-UTR AU-rich region binding	9/3991	30/18639	0.3	1.40107742420446	0.175490077661016	0.518316932914727
GO:0008374	O-acyltransferase activity	15/3991	55/18639	0.272727272727273	1.27370674927678	0.183163587902475	0.539786732560275
GO:0032934	sterol binding	18/3991	68/18639	0.264705882352941	1.23624478606276	0.189997297601882	0.558692494049587
GO:0005225	volume-sensitive anion channel activity	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0019203	carbohydrate phosphatase activity	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0019215	intermediate filament binding	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0032794	GTPase activating protein binding	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0043522	leucine zipper domain binding	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0047676	arachidonate-CoA ligase activity	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0180030	inositol phosphate kinase activity	4/3991	11/18639	0.363636363636364	1.69827566570238	0.193685008550304	0.559067832810333
GO:0015293	symporter activity	36/3991	146/18639	0.246575342465753	1.1515704856475	0.193893937521486	0.559067832810333
GO:0016776	phosphotransferase activity, phosphate group as acceptor	11/3991	39/18639	0.282051282051282	1.31725227916659	0.197266882134287	0.567567430278606
GO:0015929	hexosaminidase activity	5/3991	15/18639	0.333333333333333	1.55675269356051	0.202435176122665	0.575601769900534
GO:0017081	chloride channel regulator activity	5/3991	15/18639	0.333333333333333	1.55675269356051	0.202435176122665	0.575601769900534
GO:0050780	dopamine receptor binding	5/3991	15/18639	0.333333333333333	1.55675269356051	0.202435176122665	0.575601769900534
GO:0141050	histone H3K deacetylase activity	5/3991	15/18639	0.333333333333333	1.55675269356051	0.202435176122665	0.575601769900534
GO:0141051	histone H4K deacetylase activity	5/3991	15/18639	0.333333333333333	1.55675269356051	0.202435176122665	0.575601769900534
GO:0016411	acylglycerol O-acyltransferase activity	9/3991	31/18639	0.290322580645161	1.35588137826238	0.203108511111446	0.575601769900534
GO:0070325	lipoprotein particle receptor binding	9/3991	31/18639	0.290322580645161	1.35588137826238	0.203108511111446	0.575601769900534
GO:0019212	phosphatase inhibitor activity	15/3991	56/18639	0.267857142857143	1.25096198589684	0.203508640743859	0.575601769900534
GO:0005346	purine ribonucleotide transmembrane transporter activity	6/3991	19/18639	0.315789473684211	1.47481834126785	0.205801575278732	0.576243413548277
GO:0015245	fatty acid transmembrane transporter activity	6/3991	19/18639	0.315789473684211	1.47481834126785	0.205801575278732	0.576243413548277
GO:0042800	histone H3K4 methyltransferase activity	6/3991	19/18639	0.315789473684211	1.47481834126785	0.205801575278732	0.576243413548277
GO:0050145	nucleoside monophosphate kinase activity	6/3991	19/18639	0.315789473684211	1.47481834126785	0.205801575278732	0.576243413548277
GO:0000295	adenine nucleotide transmembrane transporter activity	7/3991	23/18639	0.304347826086957	1.42138289412047	0.206325357060731	0.576243413548277
GO:0005283	amino acid:sodium symporter activity	7/3991	23/18639	0.304347826086957	1.42138289412047	0.206325357060731	0.576243413548277
GO:0005080	protein kinase C binding	14/3991	52/18639	0.269230769230769	1.25737717556811	0.208212824724491	0.57909191876499
GO:0030159	signaling receptor complex adaptor activity	14/3991	52/18639	0.269230769230769	1.25737717556811	0.208212824724491	0.57909191876499
GO:0008017	microtubule binding	65/3991	276/18639	0.235507246376812	1.09987962045036	0.210793096396369	0.585049446339196
GO:0140693	molecular condensate scaffold activity	13/3991	48/18639	0.270833333333333	1.26486156351792	0.213000552169252	0.589949662128531
GO:0160215	deacylase activity	17/3991	65/18639	0.261538461538462	1.22145211340902	0.213776822007962	0.590873824804616
GO:0004857	enzyme inhibitor activity	96/3991	416/18639	0.230769230769231	1.07775186477266	0.21737460611759	0.599576651171451
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	11/3991	40/18639	0.275	1.28432097218742	0.222735250975827	0.611834485705204
GO:0071949	FAD binding	11/3991	40/18639	0.275	1.28432097218742	0.222735250975827	0.611834485705204
GO:0005544	calcium-dependent phospholipid binding	14/3991	53/18639	0.264150943396226	1.23365307791588	0.230657805706656	0.63229603823077
GO:0022884	macromolecule transmembrane transporter activity	9/3991	32/18639	0.28125	1.31351008519168	0.232367463401778	0.63308278294158
GO:0051059	NF-kappaB binding	9/3991	32/18639	0.28125	1.31351008519168	0.232367463401778	0.63308278294158
GO:0120015	sterol transfer activity	9/3991	32/18639	0.28125	1.31351008519168	0.232367463401778	0.63308278294158
GO:0043178	alcohol binding	23/3991	92/18639	0.25	1.16756452017038	0.234119893746989	0.636558163242831
GO:0019789	SUMO transferase activity	8/3991	28/18639	0.285714285714286	1.3343594516233	0.236904572155967	0.642820332984178
GO:0015295	solute:proton symporter activity	7/3991	24/18639	0.291666666666667	1.36215860686545	0.240988501989577	0.643063803191743
GO:0019957	C-C chemokine binding	7/3991	24/18639	0.291666666666667	1.36215860686545	0.240988501989577	0.643063803191743
GO:0070300	phosphatidic acid binding	7/3991	24/18639	0.291666666666667	1.36215860686545	0.240988501989577	0.643063803191743
GO:0004000	adenosine deaminase activity	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0004859	phospholipase inhibitor activity	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0005095	GTPase inhibitor activity	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0010853	cyclase activator activity	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0031543	peptidyl-proline dioxygenase activity	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0035197	siRNA binding	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0043047	single-stranded telomeric DNA binding	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/3991	12/18639	0.333333333333333	1.55675269356051	0.244153571053109	0.643063803191743
GO:0001972	retinoic acid binding	6/3991	20/18639	0.3	1.40107742420446	0.244219736493044	0.643063803191743
GO:0010851	cyclase regulator activity	6/3991	20/18639	0.3	1.40107742420446	0.244219736493044	0.643063803191743
GO:0030742	GTP-dependent protein binding	6/3991	20/18639	0.3	1.40107742420446	0.244219736493044	0.643063803191743
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3991	16/18639	0.3125	1.45945565021298	0.245828043644668	0.643491055422806
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/3991	16/18639	0.3125	1.45945565021298	0.245828043644668	0.643491055422806
GO:0097027	ubiquitin-protein transferase activator activity	5/3991	16/18639	0.3125	1.45945565021298	0.245828043644668	0.643491055422806
GO:0042169	SH2 domain binding	11/3991	41/18639	0.268292682926829	1.25299607042675	0.249426441118269	0.650359958775175
GO:0140318	protein transporter activity	11/3991	41/18639	0.268292682926829	1.25299607042675	0.249426441118269	0.650359958775175
GO:0048306	calcium-dependent protein binding	20/3991	80/18639	0.25	1.16756452017038	0.253914836561453	0.66077252789384
GO:0098631	cell adhesion mediator activity	19/3991	76/18639	0.25	1.16756452017038	0.261119197540958	0.678198694002294
GO:0019956	chemokine binding	9/3991	33/18639	0.272727272727273	1.27370674927678	0.263030631546105	0.68183668565835
GO:0051087	protein-folding chaperone binding	32/3991	134/18639	0.238805970149254	1.11528551180455	0.272218346664743	0.704285838754713
GO:0003707	nuclear steroid receptor activity	7/3991	25/18639	0.28	1.30767226259083	0.277314509578722	0.711951673629987
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/3991	25/18639	0.28	1.30767226259083	0.277314509578722	0.711951673629987
GO:0019707	protein-cysteine S-acyltransferase activity	7/3991	25/18639	0.28	1.30767226259083	0.277314509578722	0.711951673629987
GO:0120020	cholesterol transfer activity	7/3991	25/18639	0.28	1.30767226259083	0.277314509578722	0.711951673629987
GO:0098632	cell-cell adhesion mediator activity	14/3991	55/18639	0.254545454545455	1.18879296599166	0.278233354561838	0.712939593742905
GO:0036122	BMP binding	6/3991	21/18639	0.285714285714286	1.3343594516233	0.284480500315681	0.727550704830333
GO:0005109	frizzled binding	10/3991	38/18639	0.263157894736842	1.22901528438988	0.285748955013324	0.729397428188887
GO:0003774	cytoskeletal motor activity	36/3991	153/18639	0.235294117647059	1.09888425427801	0.289429768505137	0.736529771474104
GO:0008484	sulfuric ester hydrolase activity	5/3991	17/18639	0.294117647058824	1.37360531784751	0.291301662425713	0.736529771474104
GO:0036041	long-chain fatty acid binding	5/3991	17/18639	0.294117647058824	1.37360531784751	0.291301662425713	0.736529771474104
GO:0051787	misfolded protein binding	5/3991	17/18639	0.294117647058824	1.37360531784751	0.291301662425713	0.736529771474104
GO:1990226	histone methyltransferase binding	5/3991	17/18639	0.294117647058824	1.37360531784751	0.291301662425713	0.736529771474104
GO:0098531	ligand-modulated transcription factor activity	15/3991	60/18639	0.25	1.16756452017038	0.29379054816715	0.7384555110837
GO:0030332	cyclin binding	9/3991	34/18639	0.264705882352941	1.23624478606276	0.294843594334682	0.7384555110837
GO:0031072	heat shock protein binding	31/3991	131/18639	0.236641221374046	1.10517557634449	0.295266699330311	0.7384555110837
GO:0140938	histone H3 methyltransferase activity	12/3991	47/18639	0.25531914893617	1.19240631847188	0.296030692839626	0.7384555110837
GO:0017154	semaphorin receptor activity	4/3991	13/18639	0.307692307692308	1.43700248636355	0.297041655020185	0.7384555110837
GO:0035673	oligopeptide transmembrane transporter activity	4/3991	13/18639	0.307692307692308	1.43700248636355	0.297041655020185	0.7384555110837
GO:0043560	insulin receptor substrate binding	4/3991	13/18639	0.307692307692308	1.43700248636355	0.297041655020185	0.7384555110837
GO:0051011	microtubule minus-end binding	4/3991	13/18639	0.307692307692308	1.43700248636355	0.297041655020185	0.7384555110837
GO:0140852	histone ubiquitin ligase activity	4/3991	13/18639	0.307692307692308	1.43700248636355	0.297041655020185	0.7384555110837
GO:0019199	transmembrane receptor protein kinase activity	19/3991	78/18639	0.243589743589744	1.13762696837114	0.302636353378888	0.750823795898059
GO:0030170	pyridoxal phosphate binding	14/3991	56/18639	0.25	1.16756452017038	0.303141592501164	0.750823795898059
GO:0001637	G protein-coupled chemoattractant receptor activity	7/3991	26/18639	0.269230769230769	1.25737717556811	0.314881698043911	0.774156660936686
GO:0004950	chemokine receptor activity	7/3991	26/18639	0.269230769230769	1.25737717556811	0.314881698043911	0.774156660936686
GO:0008198	ferrous iron binding	7/3991	26/18639	0.269230769230769	1.25737717556811	0.314881698043911	0.774156660936686
GO:0015216	purine nucleotide transmembrane transporter activity	7/3991	26/18639	0.269230769230769	1.25737717556811	0.314881698043911	0.774156660936686
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	10/3991	39/18639	0.256410256410256	1.19750207196962	0.316260014626785	0.776116028541834
GO:0031683	G-protein beta/gamma-subunit complex binding	6/3991	22/18639	0.272727272727273	1.27370674927678	0.326012387794698	0.795660946445926
GO:0050321	tau-protein kinase activity	6/3991	22/18639	0.272727272727273	1.27370674927678	0.326012387794698	0.795660946445926
GO:0140517	protein-RNA adaptor activity	6/3991	22/18639	0.272727272727273	1.27370674927678	0.326012387794698	0.795660946445926
GO:0015932	nucleobase-containing compound transmembrane transporter activity	14/3991	57/18639	0.245614035087719	1.14708093209722	0.328637944514745	0.797693919867609
GO:0016504	peptidase activator activity	14/3991	57/18639	0.245614035087719	1.14708093209722	0.328637944514745	0.797693919867609
GO:0070279	vitamin B6 binding	14/3991	57/18639	0.245614035087719	1.14708093209722	0.328637944514745	0.797693919867609
GO:0008308	voltage-gated monoatomic anion channel activity	5/3991	18/18639	0.277777777777778	1.29729391130043	0.338038698173957	0.81458783765746
GO:0015172	acidic amino acid transmembrane transporter activity	5/3991	18/18639	0.277777777777778	1.29729391130043	0.338038698173957	0.81458783765746
GO:0035615	clathrin adaptor activity	5/3991	18/18639	0.277777777777778	1.29729391130043	0.338038698173957	0.81458783765746
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/3991	18/18639	0.277777777777778	1.29729391130043	0.338038698173957	0.81458783765746
GO:0017147	Wnt-protein binding	8/3991	31/18639	0.258064516129032	1.20522789178878	0.339802104939843	0.817361819990434
GO:0015036	disulfide oxidoreductase activity	10/3991	40/18639	0.25	1.16756452017038	0.347434935843771	0.833968502028334
GO:0005161	platelet-derived growth factor receptor binding	4/3991	14/18639	0.285714285714286	1.3343594516233	0.351078875011179	0.833968502028334
GO:0008191	metalloendopeptidase inhibitor activity	4/3991	14/18639	0.285714285714286	1.3343594516233	0.351078875011179	0.833968502028334
GO:0008494	translation activator activity	4/3991	14/18639	0.285714285714286	1.3343594516233	0.351078875011179	0.833968502028334
GO:0042043	neurexin family protein binding	4/3991	14/18639	0.285714285714286	1.3343594516233	0.351078875011179	0.833968502028334
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/3991	14/18639	0.285714285714286	1.3343594516233	0.351078875011179	0.833968502028334
GO:0061665	SUMO ligase activity	4/3991	14/18639	0.285714285714286	1.3343594516233	0.351078875011179	0.833968502028334
GO:0008320	protein transmembrane transporter activity	7/3991	27/18639	0.259259259259259	1.21080765054706	0.353265704924823	0.836187439848651
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	7/3991	27/18639	0.259259259259259	1.21080765054706	0.353265704924823	0.836187439848651
GO:0016798	hydrolase activity, acting on glycosyl bonds	30/3991	130/18639	0.230769230769231	1.07775186477266	0.354025792997912	0.836503422393297
GO:0000182	rDNA binding	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0004090	carbonyl reductase (NADPH) activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0004955	prostaglandin receptor activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0005345	purine nucleobase transmembrane transporter activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0005522	profilin binding	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0016783	sulfurtransferase activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0043208	glycosphingolipid binding	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0050308	sugar-phosphatase activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0070739	protein-glutamic acid ligase activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0070740	tubulin-glutamic acid ligase activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0098505	G-rich strand telomeric DNA binding	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:1990757	ubiquitin ligase activator activity	3/3991	10/18639	0.3	1.40107742420446	0.365131782016565	0.838942406864057
GO:0015485	cholesterol binding	13/3991	54/18639	0.240740740740741	1.1243213897937	0.367092887183559	0.838942406864057
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	13/3991	54/18639	0.240740740740741	1.1243213897937	0.367092887183559	0.838942406864057
GO:0015101	organic cation transmembrane transporter activity	19/3991	81/18639	0.234567901234568	1.09549263620925	0.368160663305228	0.838942406864057
GO:0004602	glutathione peroxidase activity	6/3991	23/18639	0.260869565217391	1.2183281949604	0.368254869230215	0.838942406864057
GO:0016493	C-C chemokine receptor activity	6/3991	23/18639	0.260869565217391	1.2183281949604	0.368254869230215	0.838942406864057
GO:0017134	fibroblast growth factor binding	6/3991	23/18639	0.260869565217391	1.2183281949604	0.368254869230215	0.838942406864057
GO:0008201	heparin binding	39/3991	172/18639	0.226744186046512	1.05895386713128	0.371566374581722	0.845044480522316
GO:0140142	nucleocytoplasmic carrier activity	8/3991	32/18639	0.25	1.16756452017038	0.375613652119199	0.852796302005323
GO:0004518	nuclease activity	47/3991	209/18639	0.22488038277512	1.05024942484226	0.377962032937884	0.855637741646014
GO:0015291	secondary active transmembrane transporter activity	64/3991	287/18639	0.222996515679443	1.04145127931574	0.378653697256955	0.855637741646014
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	20/3991	86/18639	0.232558139534884	1.08610653039105	0.378787944054527	0.855637741646014
GO:0005201	extracellular matrix structural constituent	38/3991	168/18639	0.226190476190476	1.05636789920178	0.38029684468008	0.856055297963653
GO:0032813	tumor necrosis factor receptor superfamily binding	12/3991	50/18639	0.24	1.12086193936357	0.380528185421056	0.856055297963653
GO:0004879	nuclear receptor activity	14/3991	59/18639	0.23728813559322	1.10819683270409	0.380896514599558	0.856055297963653
GO:0004620	phospholipase activity	25/3991	109/18639	0.229357798165138	1.07116011024806	0.385105353088805	0.857217388594869
GO:0005229	intracellularly calcium-gated chloride channel activity	5/3991	19/18639	0.263157894736842	1.22901528438988	0.38526624206511	0.857217388594869
GO:0005520	insulin-like growth factor binding	5/3991	19/18639	0.263157894736842	1.22901528438988	0.38526624206511	0.857217388594869
GO:0070003	threonine-type peptidase activity	5/3991	19/18639	0.263157894736842	1.22901528438988	0.38526624206511	0.857217388594869
GO:0097001	ceramide binding	5/3991	19/18639	0.263157894736842	1.22901528438988	0.38526624206511	0.857217388594869
GO:0141147	intracellularly calcium-gated channel activity	5/3991	19/18639	0.263157894736842	1.22901528438988	0.38526624206511	0.857217388594869
GO:0046875	ephrin receptor binding	7/3991	28/18639	0.25	1.16756452017038	0.392052749181109	0.867977479530316
GO:0051393	alpha-actinin binding	7/3991	28/18639	0.25	1.16756452017038	0.392052749181109	0.867977479530316
GO:0051959	dynein light intermediate chain binding	7/3991	28/18639	0.25	1.16756452017038	0.392052749181109	0.867977479530316
GO:0004180	carboxypeptidase activity	11/3991	46/18639	0.239130434782609	1.11680084538037	0.39505964881163	0.873186475436301
GO:0000774	adenyl-nucleotide exchange factor activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0004467	long-chain fatty acid-CoA ligase activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0004559	alpha-mannosidase activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0004865	protein serine/threonine phosphatase inhibitor activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0031386	protein tag activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0033130	acetylcholine receptor binding	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0051371	muscle alpha-actinin binding	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0140776	protein-containing complex destabilizing activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0141047	molecular tag activity	4/3991	15/18639	0.266666666666667	1.24540215484841	0.405131129152457	0.878003339965145
GO:0005315	phosphate transmembrane transporter activity	6/3991	24/18639	0.25	1.16756452017038	0.410676991643762	0.886162365723486
GO:0030552	cAMP binding	6/3991	24/18639	0.25	1.16756452017038	0.410676991643762	0.886162365723486
GO:0019894	kinesin binding	10/3991	42/18639	0.238095238095238	1.11196620968608	0.410887269200628	0.886162365723486
GO:0003953	NAD+ nucleosidase activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0004954	prostanoid receptor activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0008046	axon guidance receptor activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0010854	adenylate cyclase regulator activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0015205	nucleobase transmembrane transporter activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0034056	estrogen response element binding	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0045294	alpha-catenin binding	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0070697	activin receptor binding	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0140537	transcription regulator activator activity	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3991	11/18639	0.272727272727273	1.27370674927678	0.429424322066412	0.900305972131809
GO:0004629	phospholipase C activity	7/3991	29/18639	0.241379310344828	1.12730367464727	0.430850592825452	0.900305972131809
GO:0005416	amino acid:monoatomic cation symporter activity	7/3991	29/18639	0.241379310344828	1.12730367464727	0.430850592825452	0.900305972131809
GO:0016417	S-acyltransferase activity	7/3991	29/18639	0.241379310344828	1.12730367464727	0.430850592825452	0.900305972131809
GO:0106222	lncRNA binding	7/3991	29/18639	0.241379310344828	1.12730367464727	0.430850592825452	0.900305972131809
GO:0005326	neurotransmitter transmembrane transporter activity	5/3991	20/18639	0.25	1.16756452017038	0.432281743922464	0.900305972131809
GO:0016004	phospholipase activator activity	5/3991	20/18639	0.25	1.16756452017038	0.432281743922464	0.900305972131809
GO:0016505	peptidase activator activity involved in apoptotic process	5/3991	20/18639	0.25	1.16756452017038	0.432281743922464	0.900305972131809
GO:0061608	nuclear import signal receptor activity	5/3991	20/18639	0.25	1.16756452017038	0.432281743922464	0.900305972131809
GO:0016298	lipase activity	29/3991	130/18639	0.223076923076923	1.04182680261357	0.435560676222229	0.90572196691071
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	40/3991	181/18639	0.220994475138122	1.03210123329979	0.439531451975605	0.912557524708294
GO:0008139	nuclear localization sequence binding	6/3991	25/18639	0.24	1.12086193936357	0.4527914596643	0.931111005280816
GO:0019211	phosphatase activator activity	6/3991	25/18639	0.24	1.12086193936357	0.4527914596643	0.931111005280816
GO:0047617	fatty acyl-CoA hydrolase activity	6/3991	25/18639	0.24	1.12086193936357	0.4527914596643	0.931111005280816
GO:0000062	fatty-acyl-CoA binding	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0015562	efflux transmembrane transporter activity	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0015923	mannosidase activity	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0022858	alanine transmembrane transporter activity	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0055102	lipase inhibitor activity	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/3991	16/18639	0.25	1.16756452017038	0.458232157655053	0.931111005280816
GO:0015179	L-amino acid transmembrane transporter activity	14/3991	62/18639	0.225806451612903	1.05457440531519	0.460572257128389	0.933078804553615
GO:0031406	carboxylic acid binding	41/3991	187/18639	0.219251336898396	1.02396032784996	0.460598451086766	0.933078804553615
GO:0004519	endonuclease activity	28/3991	127/18639	0.220472440944882	1.02966319889042	0.465372554277119	0.941321757515082
GO:0001965	G-protein alpha-subunit binding	7/3991	30/18639	0.233333333333333	1.08972688549236	0.469297104923022	0.946392197994312
GO:0033612	receptor serine/threonine kinase binding	7/3991	30/18639	0.233333333333333	1.08972688549236	0.469297104923022	0.946392197994312
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3991	21/18639	0.238095238095238	1.11196620968608	0.478469632549584	0.960068746939356
GO:0035613	RNA stem-loop binding	5/3991	21/18639	0.238095238095238	1.11196620968608	0.478469632549584	0.960068746939356
GO:0072542	protein phosphatase activator activity	5/3991	21/18639	0.238095238095238	1.11196620968608	0.478469632549584	0.960068746939356
GO:0005343	organic acid:sodium symporter activity	8/3991	35/18639	0.228571428571429	1.06748756129864	0.483143982594816	0.960068746939356
GO:0005507	copper ion binding	14/3991	63/18639	0.222222222222222	1.03783512904034	0.486990664554256	0.960068746939356
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	20/3991	91/18639	0.21978021978022	1.02643034740253	0.488756208743621	0.960068746939356
GO:0043177	organic acid binding	41/3991	189/18639	0.216931216931217	1.01312476882509	0.491126001783246	0.960068746939356
GO:0004126	cytidine deaminase activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0005049	nuclear export signal receptor activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0005436	sodium:phosphate symporter activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0008504	monoamine transmembrane transporter activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0016208	AMP binding	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0016273	arginine N-methyltransferase activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0016274	protein-arginine N-methyltransferase activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0017166	vinculin binding	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0034452	dynactin binding	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0042301	phosphate ion binding	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0070679	inositol 1,4,5 trisphosphate binding	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:1990459	transferrin receptor binding	3/3991	12/18639	0.25	1.16756452017038	0.491181239070847	0.960068746939356
GO:0016289	acyl-CoA hydrolase activity	6/3991	26/18639	0.230769230769231	1.07775186477266	0.494164388150417	0.96208613530434
GO:0030247	polysaccharide binding	6/3991	26/18639	0.230769230769231	1.07775186477266	0.494164388150417	0.96208613530434
GO:0004177	aminopeptidase activity	9/3991	40/18639	0.225	1.05080806815335	0.4951042860973	0.96208613530434
GO:0004532	RNA exonuclease activity	9/3991	40/18639	0.225	1.05080806815335	0.4951042860973	0.96208613530434
GO:0030145	manganese ion binding	15/3991	68/18639	0.220588235294118	1.03020398838563	0.495816674973323	0.96208613530434
GO:0008081	phosphoric diester hydrolase activity	19/3991	87/18639	0.218390804597701	1.01994141991896	0.503478303187039	0.973261575946751
GO:0141110	transporter inhibitor activity	10/3991	45/18639	0.222222222222222	1.03783512904034	0.505659449835309	0.973261575946751
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0005092	GDP-dissociation inhibitor activity	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0015278	intracellularly gated calcium channel activity	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0019198	transmembrane receptor protein phosphatase activity	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0032977	membrane insertase activity	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0045236	CXCR chemokine receptor binding	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:1901567	fatty acid derivative binding	4/3991	17/18639	0.235294117647059	1.09888425427801	0.509595386956389	0.973261575946751
GO:0052689	carboxylic ester hydrolase activity	20/3991	92/18639	0.217391304347826	1.01527349580033	0.510571509946633	0.973732808255365
GO:0005539	glycosaminoglycan binding	52/3991	242/18639	0.214876033057851	1.00352652973322	0.514107485914647	0.979077737084243
GO:0004190	aspartic-type endopeptidase activity	8/3991	36/18639	0.222222222222222	1.03783512904034	0.518083745005065	0.97966260563989
GO:0045505	dynein intermediate chain binding	8/3991	36/18639	0.222222222222222	1.03783512904034	0.518083745005065	0.97966260563989
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	8/3991	36/18639	0.222222222222222	1.03783512904034	0.518083745005065	0.97966260563989
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	8/3991	36/18639	0.222222222222222	1.03783512904034	0.518083745005065	0.97966260563989
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	8/3991	36/18639	0.222222222222222	1.03783512904034	0.518083745005065	0.97966260563989
GO:0030246	carbohydrate binding	60/3991	280/18639	0.214285714285714	1.00076958871747	0.521153762350713	0.982586284392462
GO:0005243	gap junction channel activity	5/3991	22/18639	0.227272727272727	1.06142229106398	0.523309998653963	0.982586284392462
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	5/3991	22/18639	0.227272727272727	1.06142229106398	0.523309998653963	0.982586284392462
GO:0016881	acid-amino acid ligase activity	5/3991	22/18639	0.227272727272727	1.06142229106398	0.523309998653963	0.982586284392462
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/3991	22/18639	0.227272727272727	1.06142229106398	0.523309998653963	0.982586284392462
GO:0003684	damaged DNA binding	16/3991	74/18639	0.216216216216216	1.00978553095817	0.528273190572125	0.989123014605591
GO:0031491	nucleosome binding	16/3991	74/18639	0.216216216216216	1.00978553095817	0.528273190572125	0.989123014605591
GO:0008266	poly(U) RNA binding	6/3991	27/18639	0.222222222222222	1.03783512904034	0.5344211547863	0.997754652612609
GO:0015370	solute:sodium symporter activity	17/3991	79/18639	0.215189873417722	1.00499224520995	0.535125341775751	0.997754652612609
GO:0033293	monocarboxylic acid binding	17/3991	79/18639	0.215189873417722	1.00499224520995	0.535125341775751	0.997754652612609
GO:0120013	lipid transfer activity	14/3991	65/18639	0.215384615384615	1.00590174045448	0.538951448926306	1
GO:0019842	vitamin binding	32/3991	150/18639	0.213333333333333	0.996321723878727	0.541766532917763	1
GO:0030544	Hsp70 protein binding	11/3991	51/18639	0.215686274509804	1.00731056642151	0.544218635087471	1
GO:0004465	lipoprotein lipase activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0005172	vascular endothelial growth factor receptor binding	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0008253	5'-nucleotidase activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0008417	fucosyltransferase activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0031994	insulin-like growth factor I binding	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0071714	icosanoid transmembrane transporter activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0097157	pre-mRNA intronic binding	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0140666	annealing activity	3/3991	13/18639	0.230769230769231	1.07775186477266	0.549423114286045	1
GO:0030551	cyclic nucleotide binding	8/3991	37/18639	0.216216216216216	1.00978553095817	0.552170749421784	1
GO:0070001	aspartic-type peptidase activity	8/3991	37/18639	0.216216216216216	1.00978553095817	0.552170749421784	1
GO:0004175	endopeptidase activity	86/3991	405/18639	0.212345679012346	0.991709123305215	0.555001510798276	1
GO:0000400	four-way junction DNA binding	4/3991	18/18639	0.222222222222222	1.03783512904034	0.558611583751369	1
GO:0008409	5'-3' exonuclease activity	4/3991	18/18639	0.222222222222222	1.03783512904034	0.558611583751369	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/3991	18/18639	0.222222222222222	1.03783512904034	0.558611583751369	1
GO:0031690	adrenergic receptor binding	4/3991	18/18639	0.222222222222222	1.03783512904034	0.558611583751369	1
GO:0070628	proteasome binding	4/3991	18/18639	0.222222222222222	1.03783512904034	0.558611583751369	1
GO:0031492	nucleosomal DNA binding	9/3991	42/18639	0.214285714285714	1.00076958871747	0.559614515296406	1
GO:0008171	O-methyltransferase activity	5/3991	23/18639	0.217391304347826	1.01527349580033	0.566380867938337	1
GO:0016866	intramolecular transferase activity	6/3991	28/18639	0.214285714285714	1.00076958871747	0.573248901769534	1
GO:0046625	sphingolipid binding	6/3991	28/18639	0.214285714285714	1.00076958871747	0.573248901769534	1
GO:0051537	2 iron, 2 sulfur cluster binding	6/3991	28/18639	0.214285714285714	1.00076958871747	0.573248901769534	1
GO:1901681	sulfur compound binding	58/3991	275/18639	0.210909090909091	0.984999886107378	0.57597534945313	1
GO:0005501	retinoid binding	8/3991	38/18639	0.210526315789474	0.983212227511902	0.585209782769482	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	8/3991	38/18639	0.210526315789474	0.983212227511902	0.585209782769482	1
GO:0019840	isoprenoid binding	8/3991	38/18639	0.210526315789474	0.983212227511902	0.585209782769482	1
GO:0043531	ADP binding	8/3991	38/18639	0.210526315789474	0.983212227511902	0.585209782769482	1
GO:0016209	antioxidant activity	18/3991	86/18639	0.209302325581395	0.977495877351949	0.585868374784759	1
GO:0042054	histone methyltransferase activity	14/3991	67/18639	0.208955223880597	0.975874822828977	0.58909970678362	1
GO:0008200	ion channel inhibitor activity	9/3991	43/18639	0.209302325581395	0.977495877351949	0.590553784937	1
GO:0070851	growth factor receptor binding	29/3991	139/18639	0.20863309352518	0.974370390933557	0.596233821825872	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	11/3991	53/18639	0.207547169811321	0.969298846933903	0.600324943798656	1
GO:0004065	arylsulfatase activity	3/3991	14/18639	0.214285714285714	1.00076958871747	0.603516997724644	1
GO:0005313	L-glutamate transmembrane transporter activity	3/3991	14/18639	0.214285714285714	1.00076958871747	0.603516997724644	1
GO:0005347	ATP transmembrane transporter activity	3/3991	14/18639	0.214285714285714	1.00076958871747	0.603516997724644	1
GO:0016530	metallochaperone activity	3/3991	14/18639	0.214285714285714	1.00076958871747	0.603516997724644	1
GO:0043176	amine binding	3/3991	14/18639	0.214285714285714	1.00076958871747	0.603516997724644	1
GO:1901612	cardiolipin binding	3/3991	14/18639	0.214285714285714	1.00076958871747	0.603516997724644	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/3991	19/18639	0.210526315789474	0.983212227511902	0.604837008201038	1
GO:0008301	DNA binding, bending	4/3991	19/18639	0.210526315789474	0.983212227511902	0.604837008201038	1
GO:0031420	alkali metal ion binding	4/3991	19/18639	0.210526315789474	0.983212227511902	0.604837008201038	1
GO:0042577	lipid phosphatase activity	4/3991	19/18639	0.210526315789474	0.983212227511902	0.604837008201038	1
GO:0120227	acyl-CoA binding	4/3991	19/18639	0.210526315789474	0.983212227511902	0.604837008201038	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	27/3991	130/18639	0.207692307692308	0.969976678295395	0.605536182314596	1
GO:0030215	semaphorin receptor binding	5/3991	24/18639	0.208333333333333	0.972970433475319	0.607355572226383	1
GO:0060229	lipase activator activity	5/3991	24/18639	0.208333333333333	0.972970433475319	0.607355572226383	1
GO:0070840	dynein complex binding	5/3991	24/18639	0.208333333333333	0.972970433475319	0.607355572226383	1
GO:0140612	DNA damage sensor activity	5/3991	24/18639	0.208333333333333	0.972970433475319	0.607355572226383	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/3991	29/18639	0.206896551724138	0.9662602925548	0.610396286711469	1
GO:0097472	cyclin-dependent protein kinase activity	6/3991	29/18639	0.206896551724138	0.9662602925548	0.610396286711469	1
GO:0005548	phospholipid transporter activity	14/3991	68/18639	0.205882352941176	0.961523722493257	0.613284196512216	1
GO:0008376	acetylgalactosaminyltransferase activity	7/3991	34/18639	0.205882352941176	0.961523722493257	0.613669954458325	1
GO:0015035	protein-disulfide reductase activity	7/3991	34/18639	0.205882352941176	0.961523722493257	0.613669954458325	1
GO:0016831	carboxy-lyase activity	7/3991	34/18639	0.205882352941176	0.961523722493257	0.613669954458325	1
GO:0004540	RNA nuclease activity	25/3991	121/18639	0.206611570247934	0.964929355512714	0.615583213624327	1
GO:0000217	DNA secondary structure binding	8/3991	39/18639	0.205128205128205	0.958001657575699	0.617037163538315	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/3991	39/18639	0.205128205128205	0.958001657575699	0.617037163538315	1
GO:0004521	RNA endonuclease activity	15/3991	73/18639	0.205479452054795	0.959642071372918	0.617255276358771	1
GO:0016248	channel inhibitor activity	9/3991	44/18639	0.204545454545455	0.955280061957586	0.620425491480171	1
GO:0035254	glutamate receptor binding	10/3991	49/18639	0.204081632653061	0.953113894016639	0.623795596909351	1
GO:0017171	serine hydrolase activity	41/3991	198/18639	0.207070707070707	0.967073642969408	0.623808049950963	1
GO:0051287	NAD binding	11/3991	54/18639	0.203703703703704	0.951348868286979	0.627125675608772	1
GO:0015103	inorganic anion transmembrane transporter activity	34/3991	165/18639	0.206060606060606	0.96235621056468	0.630375497131459	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/3991	59/18639	0.203389830508475	0.949882999460651	0.630403715453853	1
GO:0008236	serine-type peptidase activity	40/3991	194/18639	0.206185567010309	0.962939810449801	0.634672159198255	1
GO:0016853	isomerase activity	37/3991	180/18639	0.205555555555556	0.959997494362315	0.639757178664704	1
GO:0005496	steroid binding	22/3991	108/18639	0.203703703703704	0.951348868286979	0.641642467797198	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/3991	30/18639	0.2	0.934051616136307	0.645671082158581	1
GO:0008187	poly-pyrimidine tract binding	6/3991	30/18639	0.2	0.934051616136307	0.645671082158581	1
GO:0031210	phosphatidylcholine binding	6/3991	30/18639	0.2	0.934051616136307	0.645671082158581	1
GO:0070566	adenylyltransferase activity	6/3991	30/18639	0.2	0.934051616136307	0.645671082158581	1
GO:0051117	ATPase binding	17/3991	84/18639	0.202380952380952	0.945171278233167	0.645885511459148	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/3991	25/18639	0.2	0.934051616136307	0.645996600366903	1
GO:0000175	3'-5'-RNA exonuclease activity	7/3991	35/18639	0.2	0.934051616136307	0.646301447424202	1
GO:0015144	carbohydrate transmembrane transporter activity	8/3991	40/18639	0.2	0.934051616136307	0.647520382898569	1
GO:0001614	purinergic nucleotide receptor activity	4/3991	20/18639	0.2	0.934051616136307	0.647975824270682	1
GO:0016502	nucleotide receptor activity	4/3991	20/18639	0.2	0.934051616136307	0.647975824270682	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/3991	20/18639	0.2	0.934051616136307	0.647975824270682	1
GO:0004129	cytochrome-c oxidase activity	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0004953	icosanoid receptor activity	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0005523	tropomyosin binding	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0008242	omega peptidase activity	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0008252	nucleotidase activity	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0030553	cGMP binding	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0031005	filamin binding	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0045504	dynein heavy chain binding	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0048531	beta-1,3-galactosyltransferase activity	3/3991	15/18639	0.2	0.934051616136307	0.653113464867691	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	12/3991	60/18639	0.2	0.934051616136307	0.655095918397281	1
GO:0001094	TFIID-class transcription factor complex binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0005528	FK506 binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0008190	eukaryotic initiation factor 4E binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0008401	retinoic acid 4-hydroxylase activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0015187	glycine transmembrane transporter activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0015643	toxic substance binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0031419	cobalamin binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0031434	mitogen-activated protein kinase kinase binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0035256	G protein-coupled glutamate receptor binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0035374	chondroitin sulfate binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0050815	phosphoserine residue binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0051880	G-quadruplex DNA binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0070097	delta-catenin binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0140940	histone H2A methyltransferase activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0141109	transporter activator activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:1990763	arrestin family protein binding	2/3991	10/18639	0.2	0.934051616136307	0.66538390750882	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/3991	41/18639	0.195121951219512	0.911269869401275	0.676556986962943	1
GO:0017080	sodium channel regulator activity	8/3991	41/18639	0.195121951219512	0.911269869401275	0.676556986962943	1
GO:0016597	amino acid binding	10/3991	51/18639	0.196078431372549	0.915736878565007	0.676997385758796	1
GO:0004033	aldo-keto reductase (NADPH) activity	7/3991	36/18639	0.194444444444444	0.908105737910298	0.677250548008132	1
GO:0055106	ubiquitin-protein transferase regulator activity	7/3991	36/18639	0.194444444444444	0.908105737910298	0.677250548008132	1
GO:0005452	solute:inorganic anion antiporter activity	6/3991	31/18639	0.193548387096774	0.903920918841587	0.678936186696292	1
GO:0072349	modified amino acid transmembrane transporter activity	6/3991	31/18639	0.193548387096774	0.903920918841587	0.678936186696292	1
GO:0008509	monoatomic anion transmembrane transporter activity	30/3991	149/18639	0.201342281879195	0.940320418929168	0.679829799375312	1
GO:0140299	molecular sensor activity	14/3991	71/18639	0.197183098591549	0.920895959571006	0.68149015315715	1
GO:0004435	phosphatidylinositol phospholipase C activity	5/3991	26/18639	0.192307692307692	0.898126553977218	0.682147127085115	1
GO:0004529	DNA exonuclease activity	5/3991	26/18639	0.192307692307692	0.898126553977218	0.682147127085115	1
GO:0030507	spectrin binding	5/3991	26/18639	0.192307692307692	0.898126553977218	0.682147127085115	1
GO:0050660	flavin adenine dinucleotide binding	17/3991	86/18639	0.197674418604651	0.923190550832396	0.686210796067826	1
GO:0015174	basic amino acid transmembrane transporter activity	4/3991	21/18639	0.19047619047619	0.889572967748864	0.687859634087411	1
GO:0051428	peptide hormone receptor binding	4/3991	21/18639	0.19047619047619	0.889572967748864	0.687859634087411	1
GO:0005126	cytokine receptor binding	56/3991	275/18639	0.203636363636364	0.95103437279333	0.68814983308037	1
GO:0015297	antiporter activity	27/3991	135/18639	0.2	0.934051616136307	0.688494555010781	1
GO:0033218	amide binding	50/3991	247/18639	0.202429149797571	0.945396372607598	0.697901396791364	1
GO:0008142	oxysterol binding	3/3991	16/18639	0.1875	0.875673390127788	0.698086074224454	1
GO:0008296	3'-5'-DNA exonuclease activity	3/3991	16/18639	0.1875	0.875673390127788	0.698086074224454	1
GO:0022841	potassium ion leak channel activity	3/3991	16/18639	0.1875	0.875673390127788	0.698086074224454	1
GO:0043023	ribosomal large subunit binding	3/3991	16/18639	0.1875	0.875673390127788	0.698086074224454	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/3991	16/18639	0.1875	0.875673390127788	0.698086074224454	1
GO:0140328	floppase activity	3/3991	16/18639	0.1875	0.875673390127788	0.698086074224454	1
GO:0015108	chloride transmembrane transporter activity	24/3991	121/18639	0.198347107438017	0.926332181292205	0.698518531797206	1
GO:0004601	peroxidase activity	11/3991	57/18639	0.192982456140351	0.901277875219243	0.70154995197207	1
GO:0005504	fatty acid binding	9/3991	47/18639	0.191489361702128	0.894304738853911	0.702625017759758	1
GO:0016859	cis-trans isomerase activity	8/3991	42/18639	0.19047619047619	0.889572967748864	0.704072862649186	1
GO:0042056	chemoattractant activity	8/3991	42/18639	0.19047619047619	0.889572967748864	0.704072862649186	1
GO:0015106	bicarbonate transmembrane transporter activity	6/3991	32/18639	0.1875	0.875673390127788	0.710104551695018	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/3991	27/18639	0.185185185185185	0.864862607533617	0.715721211698481	1
GO:0005104	fibroblast growth factor receptor binding	5/3991	27/18639	0.185185185185185	0.864862607533617	0.715721211698481	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/3991	27/18639	0.185185185185185	0.864862607533617	0.715721211698481	1
GO:0001664	G protein-coupled receptor binding	60/3991	297/18639	0.202020202020202	0.943486480945764	0.717333845280362	1
GO:0001851	complement component C3b binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0004016	adenylate cyclase activity	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0015217	ADP transmembrane transporter activity	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0019107	myristoyltransferase activity	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0019864	IgG binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0048407	platelet-derived growth factor binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0050786	RAGE receptor binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0050998	nitric-oxide synthase binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0070990	snRNP binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0140031	phosphorylation-dependent protein binding	2/3991	11/18639	0.181818181818182	0.849137832851188	0.717819370940467	1
GO:0043539	protein serine/threonine kinase activator activity	14/3991	73/18639	0.191780821917808	0.89566593328139	0.722865164873336	1
GO:0003777	microtubule motor activity	13/3991	68/18639	0.191176470588235	0.892843456600881	0.72298068232391	1
GO:1901682	sulfur compound transmembrane transporter activity	12/3991	63/18639	0.19047619047619	0.889572967748864	0.723395095485459	1
GO:0008408	3'-5' exonuclease activity	11/3991	58/18639	0.189655172413793	0.885738601508567	0.724184033455158	1
GO:0008093	cytoskeletal anchor activity	4/3991	22/18639	0.181818181818182	0.849137832851188	0.724426219739288	1
GO:0042626	ATPase-coupled transmembrane transporter activity	19/3991	98/18639	0.193877551020408	0.905458199315807	0.725146403267769	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	8/3991	43/18639	0.186046511627907	0.868885224312843	0.730020080411972	1
GO:0000146	microfilament motor activity	7/3991	38/18639	0.184210526315789	0.860310699072914	0.733809458894245	1
GO:0004549	tRNA-specific ribonuclease activity	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0004659	prenyltransferase activity	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0016018	cyclosporin A binding	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0032183	SUMO binding	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0048038	quinone binding	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0070492	oligosaccharide binding	3/3991	17/18639	0.176470588235294	0.824163190708506	0.738476935781896	1
GO:0005516	calmodulin binding	41/3991	207/18639	0.198067632850242	0.925026962840304	0.739579117628101	1
GO:0003727	single-stranded RNA binding	17/3991	89/18639	0.191011235955056	0.892071768220068	0.741506013603951	1
GO:0004527	exonuclease activity	16/3991	84/18639	0.19047619047619	0.889572967748864	0.741532007732895	1
GO:0016279	protein-lysine N-methyltransferase activity	13/3991	69/18639	0.188405797101449	0.879903696360289	0.742991154322159	1
GO:0045499	chemorepellent activity	5/3991	28/18639	0.178571428571429	0.83397465726456	0.746693452987383	1
GO:0051119	sugar transmembrane transporter activity	5/3991	28/18639	0.178571428571429	0.83397465726456	0.746693452987383	1
GO:0005506	iron ion binding	30/3991	154/18639	0.194805194805195	0.909790535197701	0.750271377477054	1
GO:0003887	DNA-directed DNA polymerase activity	4/3991	23/18639	0.173913043478261	0.812218796640267	0.757698925381594	1
GO:0005158	insulin receptor binding	4/3991	23/18639	0.173913043478261	0.812218796640267	0.757698925381594	1
GO:0043274	phospholipase binding	4/3991	23/18639	0.173913043478261	0.812218796640267	0.757698925381594	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3991	23/18639	0.173913043478261	0.812218796640267	0.757698925381594	1
GO:0099186	structural constituent of postsynapse	4/3991	23/18639	0.173913043478261	0.812218796640267	0.757698925381594	1
GO:0004222	metalloendopeptidase activity	21/3991	110/18639	0.190909090909091	0.891594724493747	0.758231975503429	1
GO:0044183	protein folding chaperone	14/3991	75/18639	0.186666666666667	0.871781508393886	0.760687154044158	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	13/3991	70/18639	0.185714285714286	0.867333643555142	0.762025348041979	1
GO:0016278	lysine N-methyltransferase activity	13/3991	70/18639	0.185714285714286	0.867333643555142	0.762025348041979	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0005165	neurotrophin receptor binding	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0005527	macrolide binding	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0015132	prostaglandin transmembrane transporter activity	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0015166	polyol transmembrane transporter activity	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0016840	carbon-nitrogen lyase activity	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0045295	gamma-catenin binding	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0097371	MDM2/MDM4 family protein binding	2/3991	12/18639	0.166666666666667	0.778376346780256	0.763146997314391	1
GO:0003697	single-stranded DNA binding	23/3991	121/18639	0.190082644628099	0.887735007071696	0.772999593437279	1
GO:0016779	nucleotidyltransferase activity	26/3991	136/18639	0.191176470588235	0.892843456600881	0.773696573145743	1
GO:0003746	translation elongation factor activity	3/3991	18/18639	0.166666666666667	0.778376346780256	0.774450006188002	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/3991	18/18639	0.166666666666667	0.778376346780256	0.774450006188002	1
GO:0017128	phospholipid scramblase activity	3/3991	18/18639	0.166666666666667	0.778376346780256	0.774450006188002	1
GO:0032393	MHC class I receptor activity	3/3991	18/18639	0.166666666666667	0.778376346780256	0.774450006188002	1
GO:0099602	neurotransmitter receptor regulator activity	3/3991	18/18639	0.166666666666667	0.778376346780256	0.774450006188002	1
GO:1901611	phosphatidylglycerol binding	3/3991	18/18639	0.166666666666667	0.778376346780256	0.774450006188002	1
GO:0003785	actin monomer binding	5/3991	29/18639	0.172413793103448	0.805216910462333	0.775088695961532	1
GO:0004181	metallocarboxypeptidase activity	5/3991	29/18639	0.172413793103448	0.805216910462333	0.775088695961532	1
GO:0099604	ligand-gated calcium channel activity	5/3991	29/18639	0.172413793103448	0.805216910462333	0.775088695961532	1
GO:0140303	intramembrane lipid transporter activity	8/3991	45/18639	0.177777777777778	0.830268103232273	0.777132797100693	1
GO:0008235	metalloexopeptidase activity	12/3991	66/18639	0.181818181818182	0.849137832851188	0.782361866321824	1
GO:0050997	quaternary ammonium group binding	7/3991	40/18639	0.175	0.817295164119268	0.783075553328612	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	11/3991	61/18639	0.180327868852459	0.842177686680277	0.785183318228262	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/3991	24/18639	0.166666666666667	0.778376346780256	0.787767596012636	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/3991	24/18639	0.166666666666667	0.778376346780256	0.787767596012636	1
GO:0004806	triacylglycerol lipase activity	4/3991	24/18639	0.166666666666667	0.778376346780256	0.787767596012636	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/3991	24/18639	0.166666666666667	0.778376346780256	0.787767596012636	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/3991	24/18639	0.166666666666667	0.778376346780256	0.787767596012636	1
GO:0015171	amino acid transmembrane transporter activity	19/3991	102/18639	0.186274509803922	0.869950034636756	0.788280286527307	1
GO:0170055	lipid transmembrane transporter activity	10/3991	56/18639	0.178571428571429	0.83397465726456	0.78866359087784	1
GO:0004623	phospholipase A2 activity	6/3991	35/18639	0.171428571428571	0.800615670973977	0.790787537076254	1
GO:0003743	translation initiation factor activity	9/3991	51/18639	0.176470588235294	0.824163190708506	0.792965624443356	1
GO:0061775	cohesin loader activity	29/3991	153/18639	0.189542483660131	0.885212315946173	0.798925646613087	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/3991	67/18639	0.17910447761194	0.836464133853409	0.799893336356295	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0009982	pseudouridine synthase activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0019104	DNA N-glycosylase activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0019855	calcium channel inhibitor activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0030955	potassium ion binding	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0032396	inhibitory MHC class I receptor activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0035325	Toll-like receptor binding	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0046974	histone H3K9 methyltransferase activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0046975	histone H3K36 methyltransferase activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0061459	L-arginine transmembrane transporter activity	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0071837	HMG box domain binding	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/3991	13/18639	0.153846153846154	0.718501243181774	0.802005885137726	1
GO:0003756	protein disulfide isomerase activity	3/3991	19/18639	0.157894736842105	0.737409170633926	0.806252443310557	1
GO:0008574	plus-end-directed microtubule motor activity	3/3991	19/18639	0.157894736842105	0.737409170633926	0.806252443310557	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/3991	19/18639	0.157894736842105	0.737409170633926	0.806252443310557	1
GO:0022840	leak channel activity	3/3991	19/18639	0.157894736842105	0.737409170633926	0.806252443310557	1
GO:0022842	narrow pore channel activity	3/3991	19/18639	0.157894736842105	0.737409170633926	0.806252443310557	1
GO:0046624	sphingolipid transporter activity	3/3991	19/18639	0.157894736842105	0.737409170633926	0.806252443310557	1
GO:0001848	complement binding	4/3991	25/18639	0.16	0.747241292909045	0.814771595183252	1
GO:0015645	fatty acid ligase activity	4/3991	25/18639	0.16	0.747241292909045	0.814771595183252	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/3991	25/18639	0.16	0.747241292909045	0.814771595183252	1
GO:0120515	fatty acid-CoA ligase activity	4/3991	25/18639	0.16	0.747241292909045	0.814771595183252	1
GO:0140223	general transcription initiation factor activity	12/3991	68/18639	0.176470588235294	0.824163190708506	0.816374619363235	1
GO:0180051	translation factor activity	15/3991	84/18639	0.178571428571429	0.83397465726456	0.822862070175447	1
GO:0005164	tumor necrosis factor receptor binding	5/3991	31/18639	0.161290322580645	0.753267432367989	0.824440686419396	1
GO:0047499	calcium-independent phospholipase A2 activity	5/3991	31/18639	0.161290322580645	0.753267432367989	0.824440686419396	1
GO:0051879	Hsp90 protein binding	7/3991	42/18639	0.166666666666667	0.778376346780256	0.825192443154839	1
GO:0048029	monosaccharide binding	13/3991	74/18639	0.175675675675676	0.820450743903513	0.828372154721852	1
GO:0016860	intramolecular oxidoreductase activity	9/3991	53/18639	0.169811320754717	0.793062692945921	0.82974977837556	1
GO:0015464	acetylcholine receptor activity	3/3991	20/18639	0.15	0.70053871210223	0.834183611376418	1
GO:0042288	MHC class I protein binding	3/3991	20/18639	0.15	0.70053871210223	0.834183611376418	1
GO:0140939	histone H4 methyltransferase activity	3/3991	20/18639	0.15	0.70053871210223	0.834183611376418	1
GO:0022829	wide pore channel activity	6/3991	37/18639	0.162162162162162	0.757339148218627	0.834216051124381	1
GO:0008195	phosphatidate phosphatase activity	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0008331	high voltage-gated calcium channel activity	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0008559	ABC-type xenobiotic transporter activity	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0015386	potassium:proton antiporter activity	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0030983	mismatched DNA binding	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0031404	chloride ion binding	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0032036	myosin heavy chain binding	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:1901474	azole transmembrane transporter activity	2/3991	14/18639	0.142857142857143	0.667179725811648	0.83508736637324	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/3991	48/18639	0.166666666666667	0.778376346780256	0.836060067328696	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/3991	48/18639	0.166666666666667	0.778376346780256	0.836060067328696	1
GO:0051082	unfolded protein binding	22/3991	121/18639	0.181818181818182	0.849137832851188	0.836433344599316	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0008143	poly(A) binding	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0015145	monosaccharide transmembrane transporter activity	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0019865	immunoglobulin binding	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0051139	metal cation:proton antiporter activity	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0070006	metalloaminopeptidase activity	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0120014	phospholipid transfer activity	4/3991	26/18639	0.153846153846154	0.718501243181774	0.838885134837459	1
GO:0005245	voltage-gated calcium channel activity	7/3991	43/18639	0.162790697674419	0.760274571273738	0.843698180354841	1
GO:0031369	translation initiation factor binding	5/3991	32/18639	0.15625	0.72972782510649	0.845614044701688	1
GO:0042910	xenobiotic transmembrane transporter activity	5/3991	32/18639	0.15625	0.72972782510649	0.845614044701688	1
GO:0070717	poly-purine tract binding	5/3991	32/18639	0.15625	0.72972782510649	0.845614044701688	1
GO:0140658	ATP-dependent chromatin remodeler activity	29/3991	158/18639	0.183544303797468	0.857199267973193	0.850912796466709	1
GO:0008514	organic anion transmembrane transporter activity	51/3991	269/18639	0.189591078066914	0.885439264367131	0.856558358230868	1
GO:0008237	metallopeptidase activity	34/3991	184/18639	0.184782608695652	0.862982471430283	0.857277794141765	1
GO:0019200	carbohydrate kinase activity	3/3991	21/18639	0.142857142857143	0.667179725811648	0.858570940924586	1
GO:0070182	DNA polymerase binding	3/3991	21/18639	0.142857142857143	0.667179725811648	0.858570940924586	1
GO:1904047	S-adenosyl-L-methionine binding	3/3991	21/18639	0.142857142857143	0.667179725811648	0.858570940924586	1
GO:0004364	glutathione transferase activity	4/3991	27/18639	0.148148148148148	0.691890086026894	0.860304947557281	1
GO:0016405	CoA-ligase activity	4/3991	27/18639	0.148148148148148	0.691890086026894	0.860304947557281	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/3991	27/18639	0.148148148148148	0.691890086026894	0.860304947557281	1
GO:0035255	ionotropic glutamate receptor binding	4/3991	27/18639	0.148148148148148	0.691890086026894	0.860304947557281	1
GO:0022804	active transmembrane transporter activity	89/3991	457/18639	0.194748358862144	0.909525096675397	0.860353959678439	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/3991	44/18639	0.159090909090909	0.742995603744789	0.860597267596149	1
GO:0015250	water channel activity	2/3991	15/18639	0.133333333333333	0.622701077424204	0.863083351220247	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/3991	15/18639	0.133333333333333	0.622701077424204	0.863083351220247	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/3991	15/18639	0.133333333333333	0.622701077424204	0.863083351220247	1
GO:0140161	monocarboxylate:sodium symporter activity	2/3991	15/18639	0.133333333333333	0.622701077424204	0.863083351220247	1
GO:0005253	monoatomic anion channel activity	18/3991	103/18639	0.174757281553398	0.816161606332695	0.864980503187975	1
GO:0140097	catalytic activity, acting on DNA	64/3991	336/18639	0.19047619047619	0.889572967748864	0.872293844723138	1
GO:0004252	serine-type endopeptidase activity	32/3991	176/18639	0.181818181818182	0.849137832851188	0.874554847332085	1
GO:0005254	chloride channel activity	14/3991	83/18639	0.168674698795181	0.787754375054716	0.876101724093959	1
GO:0008135	translation factor activity, RNA binding	14/3991	83/18639	0.168674698795181	0.787754375054716	0.876101724093959	1
GO:0000510	H3-H4 histone complex chaperone activity	27/3991	151/18639	0.178807947019868	0.835079259459612	0.878900006737837	1
GO:0140584	chromatin extrusion motor activity	27/3991	151/18639	0.178807947019868	0.835079259459612	0.878900006737837	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	27/3991	151/18639	0.178807947019868	0.835079259459612	0.878900006737837	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	27/3991	151/18639	0.178807947019868	0.835079259459612	0.878900006737837	1
GO:0005242	inward rectifier potassium channel activity	4/3991	28/18639	0.142857142857143	0.667179725811648	0.879240196652264	1
GO:0033691	sialic acid binding	3/3991	22/18639	0.136363636363636	0.636853374638391	0.879751686374896	1
GO:0061133	endopeptidase activator activity	3/3991	22/18639	0.136363636363636	0.636853374638391	0.879751686374896	1
GO:0140784	metal ion sensor activity	3/3991	22/18639	0.136363636363636	0.636853374638391	0.879751686374896	1
GO:0008175	tRNA methyltransferase activity	5/3991	34/18639	0.147058823529412	0.686802658923755	0.881630149560951	1
GO:0015020	glucuronosyltransferase activity	5/3991	34/18639	0.147058823529412	0.686802658923755	0.881630149560951	1
GO:0005010	insulin-like growth factor receptor activity	8/3991	51/18639	0.156862745098039	0.732589502852005	0.881974661969353	1
GO:0044325	transmembrane transporter binding	24/3991	136/18639	0.176470588235294	0.824163190708506	0.882657823303035	1
GO:0071855	neuropeptide receptor binding	6/3991	40/18639	0.15	0.70053871210223	0.885429761837326	1
GO:0140662	ATP-dependent protein folding chaperone	6/3991	40/18639	0.15	0.70053871210223	0.885429761837326	1
GO:0015385	sodium:proton antiporter activity	2/3991	16/18639	0.125	0.583782260085192	0.886654390791075	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/3991	16/18639	0.125	0.583782260085192	0.886654390791075	1
GO:0019841	retinol binding	2/3991	16/18639	0.125	0.583782260085192	0.886654390791075	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/3991	16/18639	0.125	0.583782260085192	0.886654390791075	1
GO:0140327	flippase activity	2/3991	16/18639	0.125	0.583782260085192	0.886654390791075	1
GO:0015616	DNA translocase activity	27/3991	152/18639	0.177631578947368	0.829585316963167	0.886882662225379	1
GO:0140674	ATP-dependent histone chaperone activity	27/3991	152/18639	0.177631578947368	0.829585316963167	0.886882662225379	1
GO:0140597	protein carrier chaperone	34/3991	188/18639	0.180851063829787	0.844621142250916	0.887981833792859	1
GO:0140104	molecular carrier activity	46/3991	249/18639	0.184738955823293	0.862778601250404	0.889420078650132	1
GO:0004867	serine-type endopeptidase inhibitor activity	16/3991	95/18639	0.168421052631579	0.786569782009521	0.890224825300753	1
GO:0008276	protein methyltransferase activity	16/3991	95/18639	0.168421052631579	0.786569782009521	0.890224825300753	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/3991	52/18639	0.153846153846154	0.718501243181774	0.894690363135963	1
GO:0034061	DNA polymerase activity	5/3991	35/18639	0.142857142857143	0.667179725811648	0.896770584975067	1
GO:0043015	gamma-tubulin binding	5/3991	35/18639	0.142857142857143	0.667179725811648	0.896770584975067	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/3991	23/18639	0.130434782608696	0.6091640974802	0.898059600523891	1
GO:0016849	phosphorus-oxygen lyase activity	3/3991	23/18639	0.130434782608696	0.6091640974802	0.898059600523891	1
GO:0031681	G-protein beta-subunit binding	3/3991	23/18639	0.130434782608696	0.6091640974802	0.898059600523891	1
GO:0005200	structural constituent of cytoskeleton	19/3991	112/18639	0.169642857142857	0.792275924401332	0.900114518643501	1
GO:0061749	forked DNA-dependent helicase activity	7/3991	47/18639	0.148936170212766	0.69557035244193	0.902506965073954	1
GO:0140359	ABC-type transporter activity	7/3991	47/18639	0.148936170212766	0.69557035244193	0.902506965073954	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	7/3991	47/18639	0.148936170212766	0.69557035244193	0.902506965073954	1
GO:0005246	calcium channel regulator activity	8/3991	53/18639	0.150943396226415	0.70494461595193	0.906235355982257	1
GO:0038064	collagen receptor activity	8/3991	53/18639	0.150943396226415	0.70494461595193	0.906235355982257	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0008569	minus-end-directed microtubule motor activity	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0009881	photoreceptor activity	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0030548	acetylcholine receptor regulator activity	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0038191	neuropilin binding	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0045125	bioactive lipid receptor activity	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0070402	NADPH binding	2/3991	17/18639	0.117647058823529	0.549442127139004	0.906411384792299	1
GO:0003689	DNA clamp loader activity	28/3991	160/18639	0.175	0.817295164119268	0.907127230585912	1
GO:0003796	lysozyme activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0004983	neuropeptide Y receptor activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0005337	nucleoside transmembrane transporter activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0008519	ammonium channel activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0015203	polyamine transmembrane transporter activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0016427	tRNA (cytidine) methyltransferase activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0031996	thioesterase binding	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0033204	ribonuclease P RNA binding	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0042166	acetylcholine binding	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0043121	neurotrophin binding	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0043295	glutathione binding	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0051378	serotonin binding	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/3991	10/18639	0.1	0.467025808068153	0.910201012337928	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/3991	36/18639	0.138888888888889	0.648646955650213	0.91020214144042	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	5/3991	36/18639	0.138888888888889	0.648646955650213	0.91020214144042	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/3991	30/18639	0.133333333333333	0.622701077424204	0.910509393384421	1
GO:0098918	structural constituent of synapse	4/3991	30/18639	0.133333333333333	0.622701077424204	0.910509393384421	1
GO:0008307	structural constituent of muscle	6/3991	42/18639	0.142857142857143	0.667179725811648	0.911554098037759	1
GO:0015149	hexose transmembrane transporter activity	3/3991	24/18639	0.125	0.583782260085192	0.913815601168356	1
GO:0048027	mRNA 5'-UTR binding	3/3991	24/18639	0.125	0.583782260085192	0.913815601168356	1
GO:0055056	D-glucose transmembrane transporter activity	3/3991	24/18639	0.125	0.583782260085192	0.913815601168356	1
GO:0009378	four-way junction helicase activity	7/3991	48/18639	0.145833333333333	0.681079303432724	0.913851557371925	1
GO:0036121	double-stranded DNA helicase activity	7/3991	48/18639	0.145833333333333	0.681079303432724	0.913851557371925	1
GO:0043138	3'-5' DNA helicase activity	7/3991	48/18639	0.145833333333333	0.681079303432724	0.913851557371925	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	9/3991	60/18639	0.15	0.70053871210223	0.919814193765951	1
GO:0005319	lipid transporter activity	31/3991	178/18639	0.174157303370787	0.813359553377121	0.921706246871532	1
GO:0005262	calcium channel activity	22/3991	131/18639	0.16793893129771	0.784318150954151	0.922584796394311	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	2/3991	18/18639	0.111111111111111	0.51891756452017	0.922906557117836	1
GO:0005372	water transmembrane transporter activity	2/3991	18/18639	0.111111111111111	0.51891756452017	0.922906557117836	1
GO:0008525	phosphatidylcholine transporter activity	2/3991	18/18639	0.111111111111111	0.51891756452017	0.922906557117836	1
GO:0015280	ligand-gated sodium channel activity	2/3991	18/18639	0.111111111111111	0.51891756452017	0.922906557117836	1
GO:0016878	acid-thiol ligase activity	4/3991	31/18639	0.129032258064516	0.602613945894391	0.923260312934795	1
GO:0015662	P-type ion transporter activity	3/3991	25/18639	0.12	0.560430969681784	0.927321601984507	1
GO:0017056	structural constituent of nuclear pore	3/3991	25/18639	0.12	0.560430969681784	0.927321601984507	1
GO:0140358	P-type transmembrane transporter activity	3/3991	25/18639	0.12	0.560430969681784	0.927321601984507	1
GO:0061134	peptidase regulator activity	40/3991	226/18639	0.176991150442478	0.826594350563103	0.929162506721929	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0008172	S-methyltransferase activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0008199	ferric iron binding	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0008503	benzodiazepine receptor activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0008526	phosphatidylinositol transfer activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0032404	mismatch repair complex binding	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0035252	UDP-xylosyltransferase activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0042285	xylosyltransferase activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:1900750	oligopeptide binding	1/3991	11/18639	0.0909090909090909	0.424568916425594	0.929439176477674	1
GO:0140713	histone chaperone activity	28/3991	164/18639	0.170731707317073	0.797361135726116	0.93047993418224	1
GO:0030547	signaling receptor inhibitor activity	6/3991	44/18639	0.136363636363636	0.636853374638391	0.93234099606502	1
GO:0005017	platelet-derived growth factor receptor activity	7/3991	50/18639	0.14	0.653836131295415	0.933158888800883	1
GO:0005019	platelet-derived growth factor beta-receptor activity	7/3991	50/18639	0.14	0.653836131295415	0.933158888800883	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/3991	32/18639	0.125	0.583782260085192	0.934352636968096	1
GO:0008381	mechanosensitive monoatomic ion channel activity	2/3991	19/18639	0.105263157894737	0.491606113755951	0.936630570506928	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/3991	19/18639	0.105263157894737	0.491606113755951	0.936630570506928	1
GO:0016918	retinal binding	2/3991	19/18639	0.105263157894737	0.491606113755951	0.936630570506928	1
GO:0022821	solute:potassium antiporter activity	2/3991	19/18639	0.105263157894737	0.491606113755951	0.936630570506928	1
GO:0034987	immunoglobulin receptor binding	2/3991	19/18639	0.105263157894737	0.491606113755951	0.936630570506928	1
GO:0042834	peptidoglycan binding	2/3991	19/18639	0.105263157894737	0.491606113755951	0.936630570506928	1
GO:0016830	carbon-carbon lyase activity	7/3991	51/18639	0.137254901960784	0.641015814995505	0.941301833978626	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/3991	33/18639	0.121212121212121	0.566091888567459	0.943969768221516	1
GO:0046943	carboxylic acid transmembrane transporter activity	32/3991	188/18639	0.170212765957447	0.794937545647921	0.944332790612389	1
GO:0003720	telomerase activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0003995	acyl-CoA dehydrogenase activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0004526	ribonuclease P activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0004875	complement receptor activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0008179	adenylate cyclase binding	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0016423	tRNA (guanine) methyltransferase activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:1990817	poly(A) RNA polymerase activity	1/3991	12/18639	0.0833333333333333	0.389188173390128	0.9445566473107	1
GO:0046982	protein heterodimerization activity	67/3991	369/18639	0.181571815718157	0.847987239581742	0.947809554400289	1
GO:0000339	RNA cap binding	2/3991	20/18639	0.1	0.467025808068153	0.948013565965873	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/3991	20/18639	0.1	0.467025808068153	0.948013565965873	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/3991	20/18639	0.1	0.467025808068153	0.948013565965873	1
GO:0016408	C-acyltransferase activity	2/3991	20/18639	0.1	0.467025808068153	0.948013565965873	1
GO:0140664	ATP-dependent DNA damage sensor activity	2/3991	20/18639	0.1	0.467025808068153	0.948013565965873	1
GO:0005342	organic acid transmembrane transporter activity	32/3991	189/18639	0.169312169312169	0.790731526887879	0.948269850691737	1
GO:0008170	N-methyltransferase activity	15/3991	98/18639	0.153061224489796	0.71483542051248	0.950053949674885	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/3991	34/18639	0.117647058823529	0.549442127139004	0.952281717376258	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	4/3991	34/18639	0.117647058823529	0.549442127139004	0.952281717376258	1
GO:0090482	vitamin transmembrane transporter activity	4/3991	34/18639	0.117647058823529	0.549442127139004	0.952281717376258	1
GO:0005179	hormone activity	21/3991	132/18639	0.159090909090909	0.742995603744789	0.954916807434833	1
GO:0015459	potassium channel regulator activity	8/3991	59/18639	0.135593220338983	0.633255332973767	0.955173594155358	1
GO:0070888	E-box binding	8/3991	59/18639	0.135593220338983	0.633255332973767	0.955173594155358	1
GO:0019843	rRNA binding	9/3991	65/18639	0.138461538461538	0.646651118863597	0.955789187825353	1
GO:0003964	RNA-directed DNA polymerase activity	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:0005542	folic acid binding	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:0031432	titin binding	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:0039706	co-receptor binding	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:0070700	BMP receptor binding	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:0140333	glycerophospholipid flippase activity	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:1901338	catecholamine binding	1/3991	13/18639	0.0769230769230769	0.359250621590887	0.956435877491781	1
GO:0001530	lipopolysaccharide binding	5/3991	41/18639	0.121951219512195	0.569543668375797	0.956780838097584	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	5/3991	41/18639	0.121951219512195	0.569543668375797	0.956780838097584	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3991	41/18639	0.121951219512195	0.569543668375797	0.956780838097584	1
GO:0050698	proteoglycan sulfotransferase activity	3/3991	28/18639	0.107142857142857	0.500384794358736	0.957008043366615	1
GO:0001846	opsonin binding	2/3991	21/18639	0.0952380952380952	0.444786483874432	0.957428579128114	1
GO:0005248	voltage-gated sodium channel activity	2/3991	21/18639	0.0952380952380952	0.444786483874432	0.957428579128114	1
GO:0009975	cyclase activity	2/3991	21/18639	0.0952380952380952	0.444786483874432	0.957428579128114	1
GO:0061891	calcium ion sensor activity	2/3991	21/18639	0.0952380952380952	0.444786483874432	0.957428579128114	1
GO:0003724	RNA helicase activity	11/3991	77/18639	0.142857142857143	0.667179725811648	0.957828690032638	1
GO:0050661	NADP binding	7/3991	54/18639	0.12962962962963	0.605403825273532	0.960697144730487	1
GO:0042379	chemokine receptor binding	10/3991	72/18639	0.138888888888889	0.648646955650213	0.961594943930125	1
GO:0004866	endopeptidase inhibitor activity	26/3991	161/18639	0.161490683229814	0.754203168308819	0.961964842327003	1
GO:0008083	growth factor activity	26/3991	162/18639	0.160493827160494	0.749547593195802	0.965041400725268	1
GO:0008970	phospholipase A1 activity	2/3991	22/18639	0.0909090909090909	0.424568916425594	0.965196268403436	1
GO:0034062	5'-3' RNA polymerase activity	2/3991	22/18639	0.0909090909090909	0.424568916425594	0.965196268403436	1
GO:0097747	RNA polymerase activity	2/3991	22/18639	0.0909090909090909	0.424568916425594	0.965196268403436	1
GO:0005344	oxygen carrier activity	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0008174	mRNA methyltransferase activity	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0015926	glucosidase activity	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0019763	immunoglobulin receptor activity	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0019992	diacylglycerol binding	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0061783	peptidoglycan muralytic activity	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/3991	14/18639	0.0714285714285714	0.333589862905824	0.965770378347053	1
GO:0005004	GPI-linked ephrin receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0005008	hepatocyte growth factor receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0005009	insulin receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0005011	macrophage colony-stimulating factor receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0005020	stem cell factor receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0008288	boss receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0036332	placental growth factor receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0038062	protein tyrosine kinase collagen receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0060175	brain-derived neurotrophic factor receptor activity	6/3991	49/18639	0.122448979591837	0.571868336409984	0.96658546419862	1
GO:0008186	ATP-dependent activity, acting on RNA	11/3991	79/18639	0.139240506329114	0.650289099841732	0.966613190599078	1
GO:0015085	calcium ion transmembrane transporter activity	23/3991	147/18639	0.156462585034014	0.730720652079424	0.968796500654142	1
GO:0048019	receptor antagonist activity	3/3991	30/18639	0.1	0.467025808068153	0.970008355749744	1
GO:0015081	sodium ion transmembrane transporter activity	26/3991	164/18639	0.158536585365854	0.740406768888536	0.970549353713218	1
GO:0005006	epidermal growth factor receptor activity	6/3991	50/18639	0.12	0.560430969681784	0.971143633571039	1
GO:0005007	fibroblast growth factor receptor activity	6/3991	50/18639	0.12	0.560430969681784	0.971143633571039	1
GO:0005212	structural constituent of eye lens	2/3991	23/18639	0.0869565217391304	0.406109398320133	0.971590236772916	1
GO:0004089	carbonate dehydratase activity	1/3991	15/18639	0.0666666666666667	0.311350538712102	0.973105165998968	1
GO:0008020	G protein-coupled photoreceptor activity	1/3991	15/18639	0.0666666666666667	0.311350538712102	0.973105165998968	1
GO:0016846	carbon-sulfur lyase activity	1/3991	15/18639	0.0666666666666667	0.311350538712102	0.973105165998968	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/3991	15/18639	0.0666666666666667	0.311350538712102	0.973105165998968	1
GO:0034483	heparan sulfate sulfotransferase activity	1/3991	15/18639	0.0666666666666667	0.311350538712102	0.973105165998968	1
GO:0050700	CARD domain binding	1/3991	15/18639	0.0666666666666667	0.311350538712102	0.973105165998968	1
GO:0005021	vascular endothelial growth factor receptor activity	6/3991	51/18639	0.117647058823529	0.549442127139004	0.975122540183361	1
GO:0005030	neurotrophin receptor activity	6/3991	51/18639	0.117647058823529	0.549442127139004	0.975122540183361	1
GO:0004386	helicase activity	24/3991	155/18639	0.154838709677419	0.72313673507327	0.97517235983142	1
GO:0016782	transferase activity, transferring sulphur-containing groups	9/3991	70/18639	0.128571428571429	0.600461753230483	0.976614047829507	1
GO:0008009	chemokine activity	5/3991	45/18639	0.111111111111111	0.51891756452017	0.976770042151191	1
GO:0005540	hyaluronic acid binding	2/3991	24/18639	0.0833333333333333	0.389188173390128	0.976842476373331	1
GO:0042562	hormone binding	13/3991	94/18639	0.138297872340426	0.645886755838936	0.977461180067865	1
GO:0017116	single-stranded DNA helicase activity	7/3991	58/18639	0.120689655172414	0.563651837323633	0.977533462756378	1
GO:0061135	endopeptidase regulator activity	29/3991	184/18639	0.157608695652174	0.736073284455242	0.978595507299147	1
GO:0003688	DNA replication origin binding	1/3991	16/18639	0.0625	0.291891130042596	0.978868551012827	1
GO:0005149	interleukin-1 receptor binding	1/3991	16/18639	0.0625	0.291891130042596	0.978868551012827	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/3991	32/18639	0.09375	0.437836695063894	0.979223740587052	1
GO:0036002	pre-mRNA binding	7/3991	59/18639	0.11864406779661	0.554098416352046	0.980543445068054	1
GO:0030414	peptidase inhibitor activity	26/3991	169/18639	0.153846153846154	0.718501243181774	0.981114090102575	1
GO:0005537	D-mannose binding	2/3991	25/18639	0.08	0.373620646454523	0.981148639363663	1
GO:0015271	outward rectifier potassium channel activity	2/3991	25/18639	0.08	0.373620646454523	0.981148639363663	1
GO:0005003	ephrin receptor activity	6/3991	53/18639	0.113207547169811	0.528708461963947	0.981600467670747	1
GO:0005005	transmembrane-ephrin receptor activity	6/3991	53/18639	0.113207547169811	0.528708461963947	0.981600467670747	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/3991	40/18639	0.1	0.467025808068153	0.982508566374014	1
GO:0141108	transporter regulator activity	26/3991	170/18639	0.152941176470588	0.714274765280705	0.982765117424985	1
GO:0046873	metal ion transmembrane transporter activity	79/3991	450/18639	0.175555555555556	0.819889751941869	0.98282382658709	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/3991	47/18639	0.106382978723404	0.49683596602995	0.983143569584297	1
GO:0005112	Notch binding	2/3991	26/18639	0.0769230769230769	0.359250621590887	0.984672959864676	1
GO:0005227	calcium-activated cation channel activity	2/3991	26/18639	0.0769230769230769	0.359250621590887	0.984672959864676	1
GO:0016500	protein-hormone receptor activity	8/3991	67/18639	0.119402985074627	0.557642755902273	0.984774474812553	1
GO:0008094	ATP-dependent activity, acting on DNA	33/3991	210/18639	0.157142857142857	0.733897698392812	0.985104640826262	1
GO:0004812	aminoacyl-tRNA ligase activity	4/3991	41/18639	0.0975609756097561	0.455634934700637	0.985289942403898	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	4/3991	41/18639	0.0975609756097561	0.455634934700637	0.985289942403898	1
GO:0042287	MHC protein binding	4/3991	41/18639	0.0975609756097561	0.455634934700637	0.985289942403898	1
GO:0038187	pattern recognition receptor activity	5/3991	48/18639	0.104166666666667	0.48648521673766	0.985674726718786	1
GO:0000049	tRNA binding	10/3991	80/18639	0.125	0.583782260085192	0.986031730153827	1
GO:0008395	steroid hydroxylase activity	2/3991	27/18639	0.0740740740740741	0.345945043013447	0.987552734727786	1
GO:0016229	steroid dehydrogenase activity	3/3991	35/18639	0.0857142857142857	0.400307835486989	0.988158831029009	1
GO:0046906	tetrapyrrole binding	22/3991	152/18639	0.144736842105263	0.675958406414432	0.98869782737496	1
GO:0022853	active monoatomic ion transmembrane transporter activity	16/3991	118/18639	0.135593220338983	0.633255332973767	0.989317448025623	1
GO:0048020	CCR chemokine receptor binding	5/3991	50/18639	0.1	0.467025808068153	0.989699553043304	1
GO:0099589	serotonin receptor activity	1/3991	19/18639	0.0526315789473684	0.245803056877975	0.989751215982007	1
GO:0020037	heme binding	20/3991	142/18639	0.140845070422535	0.657782828265005	0.990240187284702	1
GO:0099106	ion channel regulator activity	23/3991	160/18639	0.14375	0.67134959909797	0.991083825488129	1
GO:0005272	sodium channel activity	5/3991	51/18639	0.0980392156862745	0.457868439282503	0.991284010962863	1
GO:0015399	primary active transmembrane transporter activity	24/3991	166/18639	0.144578313253012	0.675218035761186	0.991374296522058	1
GO:0030280	structural constituent of skin epidermis	3/3991	37/18639	0.0810810810810811	0.378669574109314	0.99191561679933	1
GO:0016874	ligase activity	24/3991	167/18639	0.143712574850299	0.671174813990161	0.992205092002929	1
GO:0016247	channel regulator activity	24/3991	168/18639	0.142857142857143	0.667179725811648	0.992961666883212	1
GO:0022839	monoatomic ion-gated channel activity	2/3991	30/18639	0.0666666666666667	0.311350538712102	0.993374424816734	1
GO:0015125	bile acid transmembrane transporter activity	1/3991	21/18639	0.0476190476190476	0.222393241937216	0.993673902167698	1
GO:0008146	sulfotransferase activity	5/3991	53/18639	0.0943396226415094	0.440590384969956	0.993784021363914	1
GO:0017046	peptide hormone binding	5/3991	53/18639	0.0943396226415094	0.440590384969956	0.993784021363914	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/3991	60/18639	0.1	0.467025808068153	0.993887478016589	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/3991	46/18639	0.0869565217391304	0.406109398320133	0.993942222430034	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	4/3991	46/18639	0.0869565217391304	0.406109398320133	0.993942222430034	1
GO:0008173	RNA methyltransferase activity	7/3991	67/18639	0.104477611940299	0.487937411414489	0.994151030026923	1
GO:0003678	DNA helicase activity	8/3991	74/18639	0.108108108108108	0.504892765479085	0.994506055010776	1
GO:0005184	neuropeptide hormone activity	2/3991	31/18639	0.0645161290322581	0.301306972947196	0.994640448968041	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/3991	31/18639	0.0645161290322581	0.301306972947196	0.994640448968041	1
GO:0070034	telomerase RNA binding	1/3991	22/18639	0.0454545454545455	0.212284458212797	0.995029979965997	1
GO:0030515	snoRNA binding	2/3991	32/18639	0.0625	0.291891130042596	0.995668229526774	1
GO:0160041	neuropeptide activity	2/3991	32/18639	0.0625	0.291891130042596	0.995668229526774	1
GO:0008188	neuropeptide receptor activity	4/3991	48/18639	0.0833333333333333	0.389188173390128	0.995789659326819	1
GO:0051536	iron-sulfur cluster binding	8/3991	76/18639	0.105263157894737	0.491606113755951	0.995939238458758	1
GO:0015078	proton transmembrane transporter activity	26/3991	185/18639	0.140540540540541	0.65636059512281	0.996038732853264	1
GO:0140102	catalytic activity, acting on a rRNA	1/3991	23/18639	0.0434782608695652	0.203054699160067	0.996095422838409	1
GO:0042923	neuropeptide binding	2/3991	33/18639	0.0606060606060606	0.283045944283729	0.996501719314075	1
GO:0051540	metal cluster binding	8/3991	77/18639	0.103896103896104	0.485221618772107	0.996514761066885	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	15/3991	122/18639	0.122950819672131	0.574212059100189	0.996807335715919	1
GO:0019825	oxygen binding	2/3991	34/18639	0.0588235294117647	0.274721063569502	0.997176976904524	1
GO:0016835	carbon-oxygen lyase activity	8/3991	79/18639	0.10126582278481	0.472937527157624	0.997441025058931	1
GO:0016887	ATP hydrolysis activity	67/3991	417/18639	0.160671462829736	0.750377197615498	0.99770700031544	1
GO:0004497	monooxygenase activity	12/3991	106/18639	0.113207547169811	0.528708461963947	0.997766970830523	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	16/3991	132/18639	0.121212121212121	0.566091888567459	0.998049747839914	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	9/3991	88/18639	0.102272727272727	0.477640030978793	0.99820701238785	1
GO:0140101	catalytic activity, acting on a tRNA	17/3991	139/18639	0.122302158273381	0.571182642961051	0.998252685323365	1
GO:0016836	hydro-lyase activity	5/3991	61/18639	0.0819672131147541	0.382808039400126	0.998465982751511	1
GO:0015252	proton channel activity	1/3991	27/18639	0.037037037037037	0.172972521506723	0.998512784768544	1
GO:0140098	catalytic activity, acting on RNA	60/3991	387/18639	0.155038759689922	0.724071020260703	0.998766178022086	1
GO:0099094	ligand-gated monoatomic cation channel activity	16/3991	136/18639	0.117647058823529	0.549442127139004	0.998838255123412	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	21/3991	167/18639	0.125748502994012	0.58727796224139	0.998892507175742	1
GO:0008168	methyltransferase activity	26/3991	204/18639	0.127450980392157	0.595228971067254	0.999514754441411	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	5/3991	68/18639	0.0735294117647059	0.343401329461877	0.999571894660151	1
GO:0022832	voltage-gated channel activity	21/3991	175/18639	0.12	0.560430969681784	0.999586961091539	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/3991	53/18639	0.0566037735849057	0.264354230981974	0.999669821985721	1
GO:0005244	voltage-gated monoatomic ion channel activity	20/3991	173/18639	0.115606936416185	0.539914228980524	0.999759326370776	1
GO:0005125	cytokine activity	30/3991	234/18639	0.128205128205128	0.598751035984812	0.999760807410611	1
GO:0016829	lyase activity	24/3991	200/18639	0.12	0.560430969681784	0.999818286778367	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3991	56/18639	0.0535714285714286	0.250192397179368	0.999822611144069	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	5/3991	73/18639	0.0684931506849315	0.319880690457639	0.999832117930559	1
GO:0016741	transferase activity, transferring one-carbon groups	26/3991	215/18639	0.12093023255814	0.564775395803348	0.999870525061418	1
GO:0015079	potassium ion transmembrane transporter activity	17/3991	160/18639	0.10625	0.496214921072413	0.999895257006953	1
GO:0022834	ligand-gated channel activity	21/3991	188/18639	0.111702127659574	0.521677764331448	0.99992398216469	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/3991	69/18639	0.0579710144927536	0.270739598880089	0.999926185571149	1
GO:0022843	voltage-gated monoatomic cation channel activity	14/3991	143/18639	0.0979020979020979	0.457228063842947	0.999930790509864	1
GO:0009055	electron transfer activity	10/3991	116/18639	0.0862068965517241	0.402608455231167	0.999937862527984	1
GO:0008227	G protein-coupled amine receptor activity	1/3991	41/18639	0.024390243902439	0.113908733675159	0.99994937437947	1
GO:0015276	ligand-gated monoatomic ion channel activity	20/3991	186/18639	0.10752688172043	0.502178288245326	0.99995828331674	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/3991	63/18639	0.0476190476190476	0.222393241937216	0.999959177443315	1
GO:0022835	transmitter-gated channel activity	3/3991	63/18639	0.0476190476190476	0.222393241937216	0.999959177443315	1
GO:0017069	snRNA binding	2/3991	54/18639	0.037037037037037	0.172972521506723	0.999965498802638	1
GO:0005249	voltage-gated potassium channel activity	7/3991	98/18639	0.0714285714285714	0.333589862905824	0.999970199424453	1
GO:0008528	G protein-coupled peptide receptor activity	10/3991	122/18639	0.0819672131147541	0.382808039400126	0.999977204677692	1
GO:0051539	4 iron, 4 sulfur cluster binding	1/3991	45/18639	0.0222222222222222	0.103783512904034	0.999980737563679	1
GO:0005267	potassium channel activity	10/3991	124/18639	0.0806451612903226	0.376633716183995	0.999983761496475	1
GO:0003823	antigen binding	17/3991	174/18639	0.0977011494252874	0.456289582595322	0.999986343972879	1
GO:0001653	peptide receptor activity	10/3991	128/18639	0.078125	0.364863912553245	0.999991816469086	1
GO:0030594	neurotransmitter receptor activity	6/3991	97/18639	0.0618556701030928	0.28888194313494	0.99999189904356	1
GO:0003730	mRNA 3'-UTR binding	28/3991	262/18639	0.106870229007634	0.499111550607187	0.999998558283169	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/3991	58/18639	0.0172413793103448	0.0805216910462333	0.999999168018978	1
GO:0005261	monoatomic cation channel activity	39/3991	341/18639	0.114369501466276	0.534135088406392	0.999999578778856	1
GO:0005216	monoatomic ion channel activity	56/3991	448/18639	0.125	0.583782260085192	0.999999712857247	1
GO:0022836	gated channel activity	34/3991	318/18639	0.106918238993711	0.499335769632617	0.99999986607593	1
GO:0003735	structural constituent of ribosome	3/3991	175/18639	0.0171428571428571	0.0800615670973977	1	1
GO:0030371	translation repressor activity	9/3991	329/18639	0.027355623100304	0.127757819836273	1	1
GO:0045182	translation regulator activity	15/3991	356/18639	0.0421348314606742	0.196780537107368	1	1
GO:1903231	mRNA base-pairing translational repressor activity	1/3991	298/18639	0.00335570469798658	0.0156720069821528	1	1