ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	198/4553	489/18639	0.404907975460123	1.65760592018476	1.51756575638841e-15	1.32296877943928e-12
GO:0060589	nucleoside-triphosphatase regulator activity	198/4553	490/18639	0.404081632653061	1.6542230509599	1.94126013123885e-15	1.32296877943928e-12
GO:0003712	transcription coregulator activity	196/4553	495/18639	0.395959595959596	1.62097318451371	2.90029034290885e-14	1.31769857912825e-11
GO:0019787	ubiquitin-like protein transferase activity	182/4553	479/18639	0.379958246346555	1.55546711040049	1.67497148423315e-11	5.70746533252447e-09
GO:0140097	catalytic activity, acting on DNA	134/4553	336/18639	0.398809523809524	1.63264017445326	1.98615750658731e-10	5.26515209746332e-08
GO:0005096	GTPase activator activity	113/4553	271/18639	0.416974169741697	1.707002317113	2.31774853886867e-10	5.26515209746332e-08
GO:0005085	guanyl-nucleotide exchange factor activity	99/4553	230/18639	0.430434782608696	1.76210716297902	3.76148840431949e-10	6.80366866344814e-08
GO:0004842	ubiquitin-protein transferase activity	168/4553	449/18639	0.374164810690423	1.53175003436389	3.9933491788397e-10	6.80366866344814e-08
GO:0016755	aminoacyltransferase activity	182/4553	496/18639	0.366935483870968	1.50215472960048	4.60595743684007e-10	6.97546665157002e-08
GO:0140297	DNA-binding transcription factor binding	179/4553	488/18639	0.366803278688525	1.50161351009783	6.62124382987814e-10	9.0247553401239e-08
GO:0042393	histone binding	102/4553	247/18639	0.412955465587045	1.69055060906587	3.20802299779189e-09	3.97503213271849e-07
GO:0001216	DNA-binding transcription activator activity	175/4553	491/18639	0.356415478615071	1.45908809705827	1.19121102537298e-08	1.27165559064534e-06
GO:0004386	helicase activity	70/4553	155/18639	0.451612903225806	1.84880582104674	1.28011803496884e-08	1.27165559064534e-06
GO:0140030	modification-dependent protein binding	76/4553	173/18639	0.439306358381503	1.79842548075397	1.37722615943182e-08	1.27165559064534e-06
GO:0003713	transcription coactivator activity	103/4553	256/18639	0.40234375	1.64710853420821	1.39947423768746e-08	1.27165559064534e-06
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	172/4553	484/18639	0.355371900826446	1.45481591467255	2.01261064304952e-08	1.71449269154781e-06
GO:0019902	phosphatase binding	80/4553	190/18639	0.421052631578947	1.72369866022403	5.67830874584368e-08	4.55266754152055e-06
GO:0061659	ubiquitin-like protein ligase activity	136/4553	372/18639	0.365591397849462	1.49665233132355	9.22190894803953e-08	6.98303438676549e-06
GO:0001217	DNA-binding transcription repressor activity	107/4553	278/18639	0.384892086330935	1.57566518715623	1.14454085161727e-07	8.21057463554917e-06
GO:0017116	single-stranded DNA helicase activity	33/4553	58/18639	0.568965517241379	2.32922211198376	1.24203337425836e-07	8.46445744557076e-06
GO:0003678	DNA helicase activity	38/4553	74/18639	0.513513513513513	2.10221356871917	5.20345783072737e-07	3.37729191584829e-05
GO:0031267	small GTPase binding	106/4553	283/18639	0.374558303886926	1.53336091064099	6.21610084229551e-07	3.85115702184035e-05
GO:0019207	kinase regulator activity	107/4553	287/18639	0.372822299651568	1.52625408372624	7.15200137042576e-07	4.23833820343057e-05
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	101/4553	268/18639	0.376865671641791	1.54280677657179	8.14970167973716e-07	4.54934702905762e-05
GO:0003689	DNA clamp loader activity	67/4553	160/18639	0.41875	1.71427218317593	8.34436358961412e-07	4.54934702905762e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	125/4553	349/18639	0.358166189111748	1.46625512823498	1.05364667633368e-06	5.52354007631851e-05
GO:0008094	ATP-dependent activity, acting on DNA	82/4553	210/18639	0.39047619047619	1.59852530513633	1.69593352618906e-06	8.46362895585043e-05
GO:0051020	GTPase binding	114/4553	315/18639	0.361904761904762	1.48156003890684	1.73867652798101e-06	8.46362895585043e-05
GO:0042578	phosphoric ester hydrolase activity	128/4553	363/18639	0.352617079889807	1.44353827192315	2.00797263086125e-06	9.37016019997194e-05
GO:0061630	ubiquitin protein ligase activity	125/4553	353/18639	0.354107648725212	1.44964033924648	2.06239769625208e-06	9.37016019997194e-05
GO:0019887	protein kinase regulator activity	95/4553	255/18639	0.372549019607843	1.52513533416881	3.03507625566016e-06	0.000133445449563381
GO:0004721	phosphoprotein phosphatase activity	70/4553	175/18639	0.4	1.63751372721283	3.51013508710757e-06	0.000149509816366488
GO:0001223	transcription coactivator binding	25/4553	44/18639	0.568181818181818	2.32601381706367	4.32442291474039e-06	0.000178611770690641
GO:0003714	transcription corepressor activity	78/4553	204/18639	0.382352941176471	1.56527047454167	7.52281467231627e-06	0.000295138579167829
GO:0061775	cohesin loader activity	62/4553	153/18639	0.405228758169935	1.65891913541169	7.57876028677477e-06	0.000295138579167829
GO:0019903	protein phosphatase binding	59/4553	144/18639	0.409722222222222	1.67731440808258	8.32059635623539e-06	0.000309636457781517
GO:0004536	DNA nuclease activity	32/4553	64/18639	0.5	2.04689215901603	8.40539173728255e-06	0.000309636457781517
GO:0140713	histone chaperone activity	65/4553	164/18639	0.396341463414634	1.62253646751271	1.09707942296489e-05	0.000385211050761315
GO:0004674	protein serine/threonine kinase activity	145/4553	433/18639	0.334872979214781	1.37089775084215	1.10221797356502e-05	0.000385211050761315
GO:0140034	methylation-dependent protein binding	36/4553	76/18639	0.473684210526316	1.93916099275203	1.1307425762751e-05	0.00038530053286574
GO:0015616	DNA translocase activity	61/4553	152/18639	0.401315789473684	1.64290028552603	1.280509733744e-05	0.000425691406608065
GO:0001221	transcription coregulator binding	49/4553	115/18639	0.426086956521739	1.74430810072671	1.35093834347905e-05	0.000438411657657607
GO:0000510	H3-H4 histone complex chaperone activity	60/4553	151/18639	0.397350993377483	1.62666926544321	2.14351547313899e-05	0.000635132954323575
GO:0140584	chromatin extrusion motor activity	60/4553	151/18639	0.397350993377483	1.62666926544321	2.14351547313899e-05	0.000635132954323575
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	60/4553	151/18639	0.397350993377483	1.62666926544321	2.14351547313899e-05	0.000635132954323575
GO:0140849	ATP-dependent H2AZ histone chaperone activity	60/4553	151/18639	0.397350993377483	1.62666926544321	2.14351547313899e-05	0.000635132954323575
GO:0019209	kinase activator activity	59/4553	148/18639	0.398648648648649	1.63198158624251	2.22970536760933e-05	0.000646614556606707
GO:0032182	ubiquitin-like protein binding	50/4553	120/18639	0.416666666666667	1.70574346584669	2.30439495258446e-05	0.000654352150077629
GO:0140658	ATP-dependent chromatin remodeler activity	62/4553	158/18639	0.392405063291139	1.60642169441765	2.48384024219629e-05	0.000690913112268069
GO:0140674	ATP-dependent histone chaperone activity	60/4553	152/18639	0.394736842105263	1.61596749396003	2.70634530317917e-05	0.000737749729646643
GO:0140597	protein carrier chaperone	71/4553	188/18639	0.377659574468085	1.54605684351211	3.03894111679632e-05	0.000812171910233998
GO:0016922	nuclear receptor binding	55/4553	137/18639	0.401459854014599	1.64349005468441	3.29726946007715e-05	0.000829537180024005
GO:0009378	four-way junction helicase activity	25/4553	48/18639	0.520833333333333	2.13217933230837	3.31548360145489e-05	0.000829537180024005
GO:0043138	3'-5' DNA helicase activity	25/4553	48/18639	0.520833333333333	2.13217933230837	3.31548360145489e-05	0.000829537180024005
GO:0106310	protein serine kinase activity	122/4553	361/18639	0.337950138504155	1.38349497728508	3.34958484086683e-05	0.000829537180024005
GO:0043130	ubiquitin binding	43/4553	100/18639	0.43	1.76032725675379	3.40822319012064e-05	0.000829537180024005
GO:0016791	phosphatase activity	96/4553	273/18639	0.351648351648352	1.43957250743985	4.08926425273964e-05	0.000977836346751603
GO:0035064	methylated histone binding	34/4553	74/18639	0.459459459459459	1.88092792990663	4.34118453648753e-05	0.00102017836607457
GO:0019789	SUMO transferase activity	17/4553	28/18639	0.607142857142857	2.48551190737661	4.71944689620465e-05	0.00107210101992116
GO:0046966	nuclear thyroid hormone receptor binding	17/4553	28/18639	0.607142857142857	2.48551190737661	4.71944689620465e-05	0.00107210101992116
GO:0016407	acetyltransferase activity	41/4553	96/18639	0.427083333333333	1.74838705249286	6.19958314858728e-05	0.00138525111992204
GO:0003697	single-stranded DNA binding	49/4553	121/18639	0.40495867768595	1.65781348416175	6.66199875623612e-05	0.00146456521044352
GO:0061733	protein-lysine-acetyltransferase activity	24/4553	47/18639	0.51063829787234	2.09044305601637	7.19385184977578e-05	0.00150849539557606
GO:0061749	forked DNA-dependent helicase activity	24/4553	47/18639	0.51063829787234	2.09044305601637	7.19385184977578e-05	0.00150849539557606
GO:1990518	single-stranded 3'-5' DNA helicase activity	24/4553	47/18639	0.51063829787234	2.09044305601637	7.19385184977578e-05	0.00150849539557606
GO:0004402	histone acetyltransferase activity	22/4553	42/18639	0.523809523809524	2.14436321420727	8.72853377081705e-05	0.0018025744741854
GO:0005114	type II transforming growth factor beta receptor binding	9/4553	11/18639	0.818181818181818	3.34945989657169	0.000103206979371932	0.00209956884901408
GO:0030295	protein kinase activator activity	54/4553	139/18639	0.388489208633094	1.59039103002685	0.000109643122018585	0.002169609873681
GO:0036121	double-stranded DNA helicase activity	24/4553	48/18639	0.5	2.04689215901603	0.000110722200980967	0.002169609873681
GO:1990841	promoter-specific chromatin binding	31/4553	68/18639	0.455882352941176	1.86628402733815	0.000111425305324776	0.002169609873681
GO:0140789	histone phosphatase activity	53/4553	136/18639	0.389705882352941	1.59537182982132	0.000114873024170206	0.00220523847808437
GO:0010485	histone H4 acetyltransferase activity	19/4553	35/18639	0.542857142857143	2.22234005836026	0.000141346675516984	0.00267577109346735
GO:0031625	ubiquitin protein ligase binding	102/4553	302/18639	0.337748344370861	1.38266887562672	0.000145192696992376	0.00271092665754259
GO:0015631	tubulin binding	125/4553	385/18639	0.324675324675325	1.32915075260781	0.000194358490944856	0.00357987328591675
GO:0044389	ubiquitin-like protein ligase binding	107/4553	322/18639	0.332298136645963	1.36035690071252	0.000206087326767032	0.00374529368511286
GO:0035091	phosphatidylinositol binding	96/4553	284/18639	0.338028169014085	1.38381441736295	0.000216329563899463	0.00387969994203905
GO:0140938	histone H3 methyltransferase activity	23/4553	47/18639	0.48936170212766	2.00334126201569	0.000231114285545843	0.00409102300258421
GO:0004725	protein tyrosine phosphatase activity	40/4553	98/18639	0.408163265306122	1.67093237470697	0.000245460308587424	0.00428926154621358
GO:0034212	protein N-acetyltransferase activity	25/4553	53/18639	0.471698113207547	1.93103033869437	0.000260837724341235	0.00450027618072283
GO:0061665	SUMO ligase activity	10/4553	14/18639	0.714285714285714	2.92413165573719	0.000276886889940651	0.00471746038736385
GO:0003684	damaged DNA binding	32/4553	74/18639	0.432432432432432	1.77028511050035	0.000290686864626594	0.00482953157434545
GO:0052742	phosphatidylinositol kinase activity	15/4553	26/18639	0.576923076923077	2.3617986450185	0.000293943705615828	0.00482953157434545
GO:0004520	DNA endonuclease activity	21/4553	42/18639	0.5	2.04689215901603	0.00029409473270042	0.00482953157434545
GO:0005131	growth hormone receptor binding	8/4553	10/18639	0.8	3.27502745442565	0.000348579003750289	0.00558956684837229
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	8/4553	10/18639	0.8	3.27502745442565	0.000348579003750289	0.00558956684837229
GO:0140767	enzyme-substrate adaptor activity	52/4553	139/18639	0.37410071942446	1.53148765854437	0.000429765856584963	0.00681128909913145
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	13/4553	22/18639	0.590909090909091	2.41905436974622	0.000546562521954621	0.00856281284395573
GO:0140104	molecular carrier activity	84/4553	249/18639	0.337349397590361	1.38103567355299	0.000554541547256283	0.00858909237398083
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	36/4553	89/18639	0.404494382022472	1.65591275785567	0.000599792736436002	0.00908352777513634
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	36/4553	89/18639	0.404494382022472	1.65591275785567	0.000599792736436002	0.00908352777513634
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	34/4553	83/18639	0.409638554216867	1.67697188931434	0.000641550948228314	0.00960916420258453
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	48/4553	128/18639	0.375	1.53516911926202	0.000657385970181439	0.00973931605823154
GO:0140793	histone H2AXY142 phosphatase activity	36/4553	90/18639	0.4	1.63751372721283	0.00076744112351346	0.0112475510897725
GO:0008017	microtubule binding	91/4553	276/18639	0.329710144927536	1.34976222080043	0.000780470816310774	0.0113168268365062
GO:0004722	protein serine/threonine phosphatase activity	40/4553	103/18639	0.388349514563107	1.58981915263381	0.000810997758717364	0.011635683632966
GO:0051019	mitogen-activated protein kinase binding	15/4553	28/18639	0.535714285714286	2.19309874180289	0.000855667392237593	0.0121486943293733
GO:0008080	N-acetyltransferase activity	29/4553	69/18639	0.420289855072464	1.72057601772362	0.000959097226865043	0.0134767991774954
GO:0140693	molecular condensate scaffold activity	22/4553	48/18639	0.458333333333333	1.87631781243136	0.000976439539473623	0.0135804805336995
GO:0002162	dystroglycan binding	8/4553	11/18639	0.727272727272727	2.9772976858415	0.00100290440209257	0.0138076636368907
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	33/4553	82/18639	0.402439024390244	1.6474985670129	0.00110231334138969	0.0150245308431414
GO:0023023	MHC protein complex binding	18/4553	37/18639	0.486486486486487	1.9915707493129	0.00118638608055032	0.0157478759014727
GO:0004529	DNA exonuclease activity	14/4553	26/18639	0.538461538461538	2.20434540201727	0.00119004491405113	0.0157478759014727
GO:0005160	transforming growth factor beta receptor binding	14/4553	26/18639	0.538461538461538	2.20434540201727	0.00119004491405113	0.0157478759014727
GO:0051010	microtubule plus-end binding	12/4553	21/18639	0.571428571428571	2.33930532458975	0.00134840871144414	0.0176719334009458
GO:0035035	histone acetyltransferase binding	13/4553	24/18639	0.541666666666667	2.2174665056007	0.00165712043623248	0.0213080674960837
GO:0140033	acetylation-dependent protein binding	13/4553	24/18639	0.541666666666667	2.2174665056007	0.00165712043623248	0.0213080674960837
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	9/4553	14/18639	0.642857142857143	2.63171849016347	0.00179933068923443	0.0218952849148155
GO:0070063	RNA polymerase binding	25/4553	59/18639	0.423728813559322	1.73465437204749	0.00182577430139909	0.0218952849148155
GO:0033192	calmodulin-dependent protein phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0140791	histone H2AXS140 phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:1990439	MAP kinase serine/threonine phosphatase activity	32/4553	81/18639	0.395061728395062	1.61729750835835	0.00186342850338855	0.0218952849148155
GO:0023026	MHC class II protein complex binding	14/4553	27/18639	0.518518518518518	2.12270297972033	0.00191974251045917	0.0223641798440671
GO:0019955	cytokine binding	51/4553	144/18639	0.354166666666667	1.44988194596969	0.00199049443418205	0.0229918975744926
GO:0002039	p53 binding	28/4553	69/18639	0.405797101449275	1.66124581021591	0.00219362551047369	0.0251253073174424
GO:0033549	MAP kinase phosphatase activity	32/4553	82/18639	0.390243902439024	1.59757436801251	0.00235054220706784	0.0259769038478117
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	8/4553	12/18639	0.666666666666667	2.72918954535471	0.00236326931557494	0.0259769038478117
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	8/4553	12/18639	0.666666666666667	2.72918954535471	0.00236326931557494	0.0259769038478117
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	8/4553	12/18639	0.666666666666667	2.72918954535471	0.00236326931557494	0.0259769038478117
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	8/4553	12/18639	0.666666666666667	2.72918954535471	0.00236326931557494	0.0259769038478117
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	25/4553	60/18639	0.416666666666667	1.70574346584669	0.00241325995084173	0.0263141865039782
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	10/4553	17/18639	0.588235294117647	2.4081084223718	0.00256367163833747	0.0275140507327084
GO:0019198	transmembrane receptor protein phosphatase activity	10/4553	17/18639	0.588235294117647	2.4081084223718	0.00256367163833747	0.0275140507327084
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	75/4553	229/18639	0.327510917030568	1.34075905612404	0.00260630177676724	0.027753041576045
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	13/4553	25/18639	0.52	2.12876784537667	0.0026858446235162	0.0281600478604045
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	13/4553	25/18639	0.52	2.12876784537667	0.0026858446235162	0.0281600478604045
GO:0000149	SNARE binding	39/4553	106/18639	0.367924528301887	1.50620366418161	0.00297738147203023	0.0309784041708183
GO:0099122	RNA polymerase II C-terminal domain binding	7/4553	10/18639	0.7	2.86564902262245	0.00302993136752468	0.0312770612844119
GO:0004679	AMP-activated protein kinase activity	80/4553	248/18639	0.32258064516129	1.32057558646196	0.00305198030141364	0.0312770612844119
GO:0035173	histone kinase activity	111/4553	360/18639	0.308333333333333	1.26225016472655	0.00312723349587702	0.0318090989170177
GO:0042809	nuclear vitamin D receptor binding	9/4553	15/18639	0.6	2.45627059081924	0.00352584326409529	0.0353198059832167
GO:0120283	protein serine/threonine kinase binding	9/4553	15/18639	0.6	2.45627059081924	0.00352584326409529	0.0353198059832167
GO:0141003	histone H2AX kinase activity	109/4553	354/18639	0.307909604519774	1.26051551035451	0.0035501198970658	0.0353198059832167
GO:0004527	exonuclease activity	32/4553	84/18639	0.380952380952381	1.55953688305983	0.00365810994728575	0.0357992376729764
GO:0017018	myosin phosphatase activity	32/4553	84/18639	0.380952380952381	1.55953688305983	0.00365810994728575	0.0357992376729764
GO:0140857	histone H3T45 kinase activity	79/4553	246/18639	0.321138211382114	1.31467057367696	0.00367710438313771	0.0357992376729764
GO:0003887	DNA-directed DNA polymerase activity	12/4553	23/18639	0.521739130434783	2.1358874702776	0.00376565388109997	0.036144973520699
GO:0070577	lysine-acetylated histone binding	12/4553	23/18639	0.521739130434783	2.1358874702776	0.00376565388109997	0.036144973520699
GO:0003779	actin binding	133/4553	443/18639	0.300225733634311	1.22905940022182	0.00383200516615532	0.0365246366536343
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	78/4553	243/18639	0.320987654320988	1.31405422554116	0.00393240590111353	0.0372213141890121
GO:0045309	protein phosphorylated amino acid binding	24/4553	59/18639	0.406779661016949	1.66526819716559	0.00423590531633483	0.0390907909920563
GO:0140375	immune receptor activity	53/4553	156/18639	0.33974358974359	1.39083697984423	0.00449618835769979	0.0390907909920563
GO:0000287	magnesium ion binding	74/4553	230/18639	0.321739130434783	1.31713060667119	0.00457058620608432	0.0390907909920563
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	43/4553	122/18639	0.352459016393443	1.44289119406048	0.00472394712062595	0.0390907909920563
GO:0140996	histone H3 kinase activity	109/4553	357/18639	0.305322128851541	1.2499229430406	0.00473554385640631	0.0390907909920563
GO:0004535	poly(A)-specific ribonuclease activity	8/4553	13/18639	0.615384615384615	2.51925188801973	0.00483151331127907	0.0390907909920563
GO:0046974	histone H3K9 methyltransferase activity	8/4553	13/18639	0.615384615384615	2.51925188801973	0.00483151331127907	0.0390907909920563
GO:0051011	microtubule minus-end binding	8/4553	13/18639	0.615384615384615	2.51925188801973	0.00483151331127907	0.0390907909920563
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	8/4553	13/18639	0.615384615384615	2.51925188801973	0.00483151331127907	0.0390907909920563
GO:0035591	signaling adaptor activity	45/4553	129/18639	0.348837209302326	1.42806429698793	0.00487336467627728	0.0390907909920563
GO:0042162	telomeric DNA binding	17/4553	38/18639	0.447368421052632	1.83142982648803	0.00487445509130455	0.0390907909920563
GO:0001727	lipid kinase activity	18/4553	41/18639	0.439024390243902	1.79727116401408	0.00487645936386802	0.0390907909920563
GO:0004676	3-phosphoinositide-dependent protein kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0004711	ribosomal protein S6 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0035175	histone H3S10 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0035979	histone H2AXS139 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0044022	histone H3S28 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0044023	histone H4S1 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0044024	histone H2AS1 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0044025	histone H2BS14 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0072354	histone H3T3 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0072371	histone H2AS121 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0072518	Rho-dependent protein serine/threonine kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0140823	histone H2BS36 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0140855	histone H3S57 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0140995	histone H2A kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0140997	histone H4 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0140998	histone H2B kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:1990244	histone H2AT120 kinase activity	78/4553	245/18639	0.318367346938775	1.30332725227143	0.00496163377962269	0.0390907909920563
GO:0004677	DNA-dependent protein kinase activity	78/4553	246/18639	0.317073170731707	1.29802917401017	0.00555802242799076	0.0435378423525943
GO:0043539	protein serine/threonine kinase activator activity	28/4553	73/18639	0.383561643835616	1.57021864253285	0.00564956498195967	0.0440020404023487
GO:0035402	histone H3T11 kinase activity	78/4553	247/18639	0.315789473684211	1.29277399516802	0.00621492661850479	0.0478584462204635
GO:0035403	histone H3T6 kinase activity	78/4553	247/18639	0.315789473684211	1.29277399516802	0.00621492661850479	0.0478584462204635
GO:1990782	protein tyrosine kinase binding	41/4553	117/18639	0.35042735042735	1.43457399178901	0.00638394762163043	0.0479399065413534
GO:0031624	ubiquitin conjugating enzyme binding	14/4553	30/18639	0.466666666666667	1.9104326817483	0.00654383540713164	0.0479399065413534
GO:0032452	histone demethylase activity	14/4553	30/18639	0.466666666666667	1.9104326817483	0.00654383540713164	0.0479399065413534
GO:0043995	histone H4K5 acetyltransferase activity	14/4553	30/18639	0.466666666666667	1.9104326817483	0.00654383540713164	0.0479399065413534
GO:0043996	histone H4K8 acetyltransferase activity	14/4553	30/18639	0.466666666666667	1.9104326817483	0.00654383540713164	0.0479399065413534
GO:0043997	histone H4K12 acetyltransferase activity	14/4553	30/18639	0.466666666666667	1.9104326817483	0.00654383540713164	0.0479399065413534
GO:0008432	JUN kinase binding	7/4553	11/18639	0.636363636363636	2.60513547511132	0.00657722855703088	0.0479399065413534
GO:0019215	intermediate filament binding	7/4553	11/18639	0.636363636363636	2.60513547511132	0.00657722855703088	0.0479399065413534
GO:0032404	mismatch repair complex binding	7/4553	11/18639	0.636363636363636	2.60513547511132	0.00657722855703088	0.0479399065413534
GO:0048185	activin binding	7/4553	11/18639	0.636363636363636	2.60513547511132	0.00657722855703088	0.0479399065413534
GO:0000217	DNA secondary structure binding	17/4553	39/18639	0.435897435897436	1.78447008734731	0.0067034188589202	0.0482991796698424
GO:0016409	palmitoyltransferase activity	16/4553	36/18639	0.444444444444444	1.81945969690314	0.0067328276869186	0.0482991796698424
GO:0044390	ubiquitin-like protein conjugating enzyme binding	16/4553	36/18639	0.444444444444444	1.81945969690314	0.0067328276869186	0.0482991796698424
GO:0004518	nuclease activity	67/4553	209/18639	0.320574162679426	1.31236147994329	0.00733792531401631	0.0523643570837918
GO:0046527	glucosyltransferase activity	10/4553	19/18639	0.526315789473684	2.15462332528004	0.00746024872016042	0.0529599948207221
GO:0004197	cysteine-type endopeptidase activity	32/4553	88/18639	0.363636363636364	1.48864884292075	0.00816130862437247	0.0576365992488067
GO:0004709	MAP kinase kinase kinase activity	12/4553	25/18639	0.48	1.96501647265539	0.0088172728974609	0.0616304767140472
GO:0042974	nuclear retinoic acid receptor binding	12/4553	25/18639	0.48	1.96501647265539	0.0088172728974609	0.0616304767140472
GO:0042813	Wnt receptor activity	8/4553	14/18639	0.571428571428571	2.33930532458975	0.00887442347400528	0.0617134652809653
GO:0030331	nuclear estrogen receptor binding	17/4553	40/18639	0.425	1.73985833516363	0.00904839153466142	0.062603845998698
GO:0141052	histone H3 demethylase activity	13/4553	28/18639	0.464285714285714	1.90068557622917	0.00914039063574673	0.0629209719016303
GO:0043394	proteoglycan binding	16/4553	37/18639	0.432432432432432	1.77028511050035	0.00921567413769046	0.0631204213551362
GO:0140457	protein demethylase activity	14/4553	31/18639	0.451612903225806	1.84880582104674	0.0092899912378049	0.0633112902856404
GO:0016887	ATP hydrolysis activity	123/4553	417/18639	0.294964028776978	1.20751911539075	0.00964830465904837	0.0654260659218056
GO:0008186	ATP-dependent activity, acting on RNA	29/4553	79/18639	0.367088607594937	1.50278158510038	0.00988922931287566	0.0667278195715323
GO:0008234	cysteine-type peptidase activity	60/4553	187/18639	0.320855614973262	1.31351368493008	0.0104938906989362	0.0701573595663775
GO:0008429	phosphatidylethanolamine binding	9/4553	17/18639	0.529411764705882	2.16729758013462	0.0105519139479878	0.0701573595663775
GO:0036041	long-chain fatty acid binding	9/4553	17/18639	0.529411764705882	2.16729758013462	0.0105519139479878	0.0701573595663775
GO:0051219	phosphoprotein binding	33/4553	93/18639	0.354838709677419	1.45263314510815	0.0109701586588327	0.0725841080193642
GO:0001784	phosphotyrosine residue binding	19/4553	47/18639	0.404255319148936	1.65493408601296	0.0111323209156062	0.0733012241930978
GO:0016278	lysine N-methyltransferase activity	26/4553	70/18639	0.371428571428571	1.52054846098334	0.0119457087635735	0.0782788511766857
GO:0042169	SH2 domain binding	17/4553	41/18639	0.414634146341463	1.6974227660133	0.0120035101556401	0.0782812647949162
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	11/4553	23/18639	0.478260869565217	1.95789684775447	0.0124077627779853	0.0798396222900439
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	11/4553	23/18639	0.478260869565217	1.95789684775447	0.0124077627779853	0.0798396222900439
GO:0035259	nuclear glucocorticoid receptor binding	7/4553	12/18639	0.583333333333333	2.38804085218537	0.0124767714950692	0.0798396222900439
GO:0035497	cAMP response element binding	7/4553	12/18639	0.583333333333333	2.38804085218537	0.0124767714950692	0.0798396222900439
GO:0008081	phosphoric diester hydrolase activity	31/4553	87/18639	0.35632183908046	1.45870475699993	0.0125615034609461	0.0800062112956523
GO:1901981	phosphatidylinositol phosphate binding	59/4553	185/18639	0.318918918918919	1.30558526899401	0.0126531062918067	0.0802015274322478
GO:0042054	histone methyltransferase activity	25/4553	67/18639	0.373134328358209	1.52753146195226	0.0127098532100994	0.0802015274322478
GO:0140463	chromatin-protein adaptor activity	21/4553	54/18639	0.388888888888889	1.59202723479025	0.0129001946811244	0.080794369433409
GO:0010484	histone H3 acetyltransferase activity	13/4553	29/18639	0.448275862068966	1.83514469429024	0.0129223569600023	0.080794369433409
GO:0004860	protein kinase inhibitor activity	30/4553	84/18639	0.357142857142857	1.4620658278686	0.0134414159607966	0.083655935865597
GO:0017124	SH3 domain binding	39/4553	115/18639	0.339130434782609	1.38832685568044	0.0137801025532857	0.0853739990005836
GO:0005543	phospholipid binding	143/4553	497/18639	0.287726358148893	1.17788965287442	0.0138512046625666	0.0854262079415305
GO:0015026	coreceptor activity	23/4553	61/18639	0.377049180327869	1.54355802155307	0.0143594584502027	0.0881619003046229
GO:0042605	peptide antigen binding	18/4553	45/18639	0.4	1.63751372721283	0.0149867523431674	0.0907884399837098
GO:0051539	4 iron, 4 sulfur cluster binding	18/4553	45/18639	0.4	1.63751372721283	0.0149867523431674	0.0907884399837098
GO:0047372	monoacylglycerol lipase activity	8/4553	15/18639	0.533333333333333	2.18335163628377	0.0149870865710453	0.0907884399837098
GO:0003777	microtubule motor activity	25/4553	68/18639	0.367647058823529	1.50506776398238	0.015536534465836	0.0937004268890904
GO:0019003	GDP binding	27/4553	75/18639	0.36	1.47376235449154	0.0164640981511792	0.0978936433385584
GO:0000400	four-way junction DNA binding	9/4553	18/18639	0.5	2.04689215901603	0.0165909256135048	0.0978936433385584
GO:0000900	mRNA regulatory element binding translation repressor activity	9/4553	18/18639	0.5	2.04689215901603	0.0165909256135048	0.0978936433385584
GO:0016854	racemase and epimerase activity	9/4553	18/18639	0.5	2.04689215901603	0.0165909256135048	0.0978936433385584
GO:0034185	apolipoprotein binding	9/4553	18/18639	0.5	2.04689215901603	0.0165909256135048	0.0978936433385584
GO:0140311	protein sequestering activity	14/4553	33/18639	0.424242424242424	1.73675698340754	0.0174191718305336	0.101866339163049
GO:0032395	MHC class II receptor activity	6/4553	10/18639	0.6	2.45627059081924	0.0175631619246637	0.101866339163049
GO:0043422	protein kinase B binding	6/4553	10/18639	0.6	2.45627059081924	0.0175631619246637	0.101866339163049
GO:0051864	histone H3K36 demethylase activity	6/4553	10/18639	0.6	2.45627059081924	0.0175631619246637	0.101866339163049
GO:0001968	fibronectin binding	13/4553	30/18639	0.433333333333333	1.77397320448056	0.0178000499121976	0.102802830636971
GO:0043998	histone H2A acetyltransferase activity	11/4553	24/18639	0.458333333333333	1.87631781243136	0.0179361727758466	0.103151913474594
GO:0004896	cytokine receptor activity	33/4553	96/18639	0.34375	1.40723835932352	0.0180674084079029	0.103470074201562
GO:0046332	SMAD binding	28/4553	79/18639	0.354430379746835	1.45096153044175	0.018407959439328	0.104979283329724
GO:0031593	polyubiquitin modification-dependent protein binding	22/4553	59/18639	0.372881355932203	1.52649584740179	0.0188262159199448	0.106551014786325
GO:0016279	protein-lysine N-methyltransferase activity	25/4553	69/18639	0.36231884057971	1.48325518769278	0.0188399079702893	0.106551014786325
GO:0030291	protein serine/threonine kinase inhibitor activity	18/4553	46/18639	0.391304347826087	1.6019156027082	0.0191213766743647	0.107696018211401
GO:0031490	chromatin DNA binding	42/4553	128/18639	0.328125	1.34327297935427	0.0196089033813214	0.109987388101815
GO:0048156	tau protein binding	17/4553	43/18639	0.395348837209302	1.61847286991965	0.0201434580512572	0.112522677556818
GO:0001540	amyloid-beta binding	29/4553	83/18639	0.349397590361446	1.43035837617988	0.0203820247837571	0.113390611348004
GO:0017154	semaphorin receptor activity	7/4553	13/18639	0.538461538461538	2.20434540201727	0.0213962393761577	0.118069126597987
GO:0140852	histone ubiquitin ligase activity	7/4553	13/18639	0.538461538461538	2.20434540201727	0.0213962393761577	0.118069126597987
GO:0097110	scaffold protein binding	25/4553	70/18639	0.357142857142857	1.4620658278686	0.0226700186406872	0.124195712807808
GO:0016410	N-acyltransferase activity	32/4553	94/18639	0.340425531914894	1.39362870401092	0.02268872523048	0.124195712807808
GO:0003724	RNA helicase activity	27/4553	77/18639	0.350649350649351	1.43548281281644	0.0234846197182271	0.126418670403468
GO:0003688	DNA replication origin binding	8/4553	16/18639	0.5	2.04689215901603	0.0236513286521529	0.126418670403468
GO:0004707	MAP kinase activity	8/4553	16/18639	0.5	2.04689215901603	0.0236513286521529	0.126418670403468
GO:0005521	lamin binding	8/4553	16/18639	0.5	2.04689215901603	0.0236513286521529	0.126418670403468
GO:0070411	I-SMAD binding	8/4553	16/18639	0.5	2.04689215901603	0.0236513286521529	0.126418670403468
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/4553	16/18639	0.5	2.04689215901603	0.0236513286521529	0.126418670403468
GO:0043495	protein-membrane adaptor activity	18/4553	47/18639	0.382978723404255	1.56783229201228	0.0240801009384218	0.128207724918238
GO:0036408	histone H3K14 acetyltransferase activity	12/4553	28/18639	0.428571428571429	1.75447899344231	0.0246405393388344	0.130681148322301
GO:0043395	heparan sulfate proteoglycan binding	9/4553	19/18639	0.473684210526316	1.93916099275203	0.0248085348175147	0.131062143241366
GO:0000030	mannosyltransferase activity	11/4553	25/18639	0.44	1.80126509993411	0.0251010226802924	0.131587284281687
GO:0008483	transaminase activity	11/4553	25/18639	0.44	1.80126509993411	0.0251010226802924	0.131587284281687
GO:0030971	receptor tyrosine kinase binding	28/4553	81/18639	0.345679012345679	1.41513531981355	0.0258358153405357	0.134920369000576
GO:0008276	protein methyltransferase activity	32/4553	95/18639	0.336842105263158	1.37895892817922	0.0264007064819968	0.137344133339548
GO:0019783	ubiquitin-like protein peptidase activity	41/4553	127/18639	0.322834645669291	1.32161540975838	0.0273117023031508	0.141543156803021
GO:0030145	manganese ion binding	24/4553	68/18639	0.352941176470588	1.44486505342308	0.0290818975374201	0.15014631190721
GO:0008408	3'-5' exonuclease activity	21/4553	58/18639	0.362068965517241	1.48223225308058	0.0299305617467679	0.153412622828068
GO:0034061	DNA polymerase activity	14/4553	35/18639	0.4	1.63751372721283	0.0300522159171638	0.153412622828068
GO:0140566	histone reader activity	14/4553	35/18639	0.4	1.63751372721283	0.0300522159171638	0.153412622828068
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	6/4553	11/18639	0.545454545454545	2.23297326438113	0.030746281965823	0.153506162342186
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	6/4553	11/18639	0.545454545454545	2.23297326438113	0.030746281965823	0.153506162342186
GO:0019864	IgG binding	6/4553	11/18639	0.545454545454545	2.23297326438113	0.030746281965823	0.153506162342186
GO:0032050	clathrin heavy chain binding	6/4553	11/18639	0.545454545454545	2.23297326438113	0.030746281965823	0.153506162342186
GO:0045294	alpha-catenin binding	6/4553	11/18639	0.545454545454545	2.23297326438113	0.030746281965823	0.153506162342186
GO:0180030	inositol phosphate kinase activity	6/4553	11/18639	0.545454545454545	2.23297326438113	0.030746281965823	0.153506162342186
GO:0004629	phospholipase C activity	12/4553	29/18639	0.413793103448276	1.69397971780637	0.0329121974885981	0.163720164879413
GO:0032454	histone H3K9 demethylase activity	7/4553	14/18639	0.5	2.04689215901603	0.0339180552783101	0.166139573903103
GO:0034236	protein kinase A catalytic subunit binding	7/4553	14/18639	0.5	2.04689215901603	0.0339180552783101	0.166139573903103
GO:0042043	neurexin family protein binding	7/4553	14/18639	0.5	2.04689215901603	0.0339180552783101	0.166139573903103
GO:0043175	RNA polymerase core enzyme binding	16/4553	42/18639	0.380952380952381	1.55953688305983	0.0340131053683998	0.166139573903103
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	11/4553	26/18639	0.423076923076923	1.73198567301357	0.0341286155186007	0.166139573903103
GO:0016779	nucleotidyltransferase activity	43/4553	136/18639	0.316176470588235	1.29435827702484	0.0341299198040123	0.166139573903103
GO:0008171	O-methyltransferase activity	10/4553	23/18639	0.434782608695652	1.77990622523133	0.0350617096237227	0.168725123048592
GO:0044013	histone H2B acetyltransferase activity	10/4553	23/18639	0.434782608695652	1.77990622523133	0.0350617096237227	0.168725123048592
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	8/4553	17/18639	0.470588235294118	1.92648673789744	0.035295252833633	0.168725123048592
GO:0046965	nuclear retinoid X receptor binding	8/4553	17/18639	0.470588235294118	1.92648673789744	0.035295252833633	0.168725123048592
GO:0030165	PDZ domain binding	28/4553	83/18639	0.337349397590361	1.38103567355299	0.0353891897551152	0.168725123048592
GO:0019210	kinase inhibitor activity	30/4553	90/18639	0.333333333333333	1.36459477267736	0.0354038042493744	0.168725123048592
GO:0015095	magnesium ion transmembrane transporter activity	9/4553	20/18639	0.45	1.84220294311443	0.0355386894701718	0.168777817936739
GO:0000993	RNA polymerase II complex binding	14/4553	36/18639	0.388888888888889	1.59202723479025	0.0384148293803634	0.181174437527458
GO:0005484	SNAP receptor activity	14/4553	36/18639	0.388888888888889	1.59202723479025	0.0384148293803634	0.181174437527458
GO:0016298	lipase activity	41/4553	130/18639	0.315384615384615	1.29111659261011	0.0393117356124975	0.184765157378738
GO:0071889	14-3-3 protein binding	13/4553	33/18639	0.393939393939394	1.61270291316415	0.0406979325805794	0.190622962568143
GO:0042826	histone deacetylase binding	40/4553	127/18639	0.31496062992126	1.28938088756916	0.0422019243163823	0.196990489189141
GO:0005126	cytokine receptor binding	80/4553	275/18639	0.290909090909091	1.1909190743366	0.042598010050807	0.19816070887116
GO:0016769	transferase activity, transferring nitrogenous groups	12/4553	30/18639	0.4	1.63751372721283	0.0429869625395319	0.198614338784346
GO:0051721	protein phosphatase 2A binding	12/4553	30/18639	0.4	1.63751372721283	0.0429869625395319	0.198614338784346
GO:0042277	peptide binding	73/4553	249/18639	0.293172690763052	1.20018576392105	0.043476734616341	0.200198612439435
GO:0003774	cytoskeletal motor activity	47/4553	153/18639	0.30718954248366	1.25756773168305	0.0448325005325466	0.205746458672932
GO:0008013	beta-catenin binding	34/4553	106/18639	0.320754716981132	1.31310063031217	0.0452565350258999	0.206995494094971
GO:0050431	transforming growth factor beta binding	10/4553	24/18639	0.416666666666667	1.70574346584669	0.0472942359436344	0.214159613259713
GO:0050699	WW domain binding	10/4553	24/18639	0.416666666666667	1.70574346584669	0.0472942359436344	0.214159613259713
GO:0070840	dynein complex binding	10/4553	24/18639	0.416666666666667	1.70574346584669	0.0472942359436344	0.214159613259713
GO:0005078	MAP-kinase scaffold activity	6/4553	12/18639	0.5	2.04689215901603	0.0490157924365769	0.217096508800661
GO:0005247	voltage-gated chloride channel activity	6/4553	12/18639	0.5	2.04689215901603	0.0490157924365769	0.217096508800661
GO:0008603	cAMP-dependent protein kinase regulator activity	6/4553	12/18639	0.5	2.04689215901603	0.0490157924365769	0.217096508800661
GO:0070008	serine-type exopeptidase activity	6/4553	12/18639	0.5	2.04689215901603	0.0490157924365769	0.217096508800661
GO:0070410	co-SMAD binding	6/4553	12/18639	0.5	2.04689215901603	0.0490157924365769	0.217096508800661
GO:1990247	N6-methyladenosine-containing RNA reader activity	6/4553	12/18639	0.5	2.04689215901603	0.0490157924365769	0.217096508800661
GO:0010314	phosphatidylinositol-5-phosphate binding	9/4553	21/18639	0.428571428571429	1.75447899344231	0.0490577584083666	0.217096508800661
GO:0004706	JUN kinase kinase kinase activity	8/4553	18/18639	0.444444444444444	1.81945969690314	0.0502587146097356	0.219559705170095
GO:0008409	5'-3' exonuclease activity	8/4553	18/18639	0.444444444444444	1.81945969690314	0.0502587146097356	0.219559705170095
GO:0030228	lipoprotein particle receptor activity	8/4553	18/18639	0.444444444444444	1.81945969690314	0.0502587146097356	0.219559705170095
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	8/4553	18/18639	0.444444444444444	1.81945969690314	0.0502587146097356	0.219559705170095
GO:0004559	alpha-mannosidase activity	7/4553	15/18639	0.466666666666667	1.9104326817483	0.0504826528971669	0.219833405427599
GO:0002020	protease binding	42/4553	136/18639	0.308823529411765	1.2642569217452	0.051244125283678	0.22173251670366
GO:0019838	growth factor binding	42/4553	136/18639	0.308823529411765	1.2642569217452	0.051244125283678	0.22173251670366
GO:0030332	cyclin binding	13/4553	34/18639	0.382352941176471	1.56527047454167	0.0515922872773025	0.221830560122912
GO:0052866	phosphatidylinositol phosphate phosphatase activity	13/4553	34/18639	0.382352941176471	1.56527047454167	0.0515922872773025	0.221830560122912
GO:0070273	phosphatidylinositol-4-phosphate binding	12/4553	31/18639	0.387096774193548	1.58469070375435	0.0550127051544411	0.235793450080199
GO:0038024	cargo receptor activity	22/4553	65/18639	0.338461538461538	1.38558853841085	0.0555594213283503	0.237390254766588
GO:0101005	deubiquitinase activity	36/4553	115/18639	0.31304347826087	1.28153248216656	0.0561614780365572	0.239212795511961
GO:0004843	cysteine-type deubiquitinase activity	34/4553	108/18639	0.314814814814815	1.28878395197306	0.0577623265339426	0.245264956591164
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	17/4553	48/18639	0.354166666666667	1.44988194596969	0.0581364375817627	0.245324967256788
GO:0032266	phosphatidylinositol-3-phosphate binding	17/4553	48/18639	0.354166666666667	1.44988194596969	0.0581364375817627	0.245324967256788
GO:0051536	iron-sulfur cluster binding	25/4553	76/18639	0.328947368421053	1.34663957830002	0.0594523523926216	0.249426361573585
GO:0140313	molecular sequestering activity	19/4553	55/18639	0.345454545454545	1.41421640077471	0.0594743708814492	0.249426361573585
GO:0017056	structural constituent of nuclear pore	10/4553	25/18639	0.4	1.63751372721283	0.0620897114525288	0.25801303874938
GO:0019706	protein-cysteine S-palmitoyltransferase activity	10/4553	25/18639	0.4	1.63751372721283	0.0620897114525288	0.25801303874938
GO:0019707	protein-cysteine S-acyltransferase activity	10/4553	25/18639	0.4	1.63751372721283	0.0620897114525288	0.25801303874938
GO:0008170	N-methyltransferase activity	31/4553	98/18639	0.316326530612245	1.2949725903979	0.063845149035964	0.26054458055701
GO:0061631	ubiquitin conjugating enzyme activity	13/4553	35/18639	0.371428571428571	1.52054846098334	0.0643205112628393	0.26054458055701
GO:0032931	histone H3K56 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0043992	histone H3K9 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0043993	histone H3K18 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0043994	histone H3K23 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0043999	histone H2AK5 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0044012	histone H2AK9 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0044014	histone H2BK5 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0044015	histone H2BK12 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0044016	histone H3K4 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0044017	histone H3K27 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0044018	histone H3K36 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0046972	histone H4K16 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0140908	histone H3K122 acetyltransferase activity	9/4553	22/18639	0.409090909090909	1.67472994828585	0.0655662444101645	0.26054458055701
GO:0051540	metal cluster binding	25/4553	77/18639	0.324675324675325	1.32915075260781	0.0682953873761607	0.2701925036094
GO:0016763	pentosyltransferase activity	17/4553	49/18639	0.346938775510204	1.42029251850092	0.0694554460569072	0.2701925036094
GO:0004708	MAP kinase kinase activity	7/4553	16/18639	0.4375	1.79103063913903	0.0713514606432887	0.2701925036094
GO:0005024	transforming growth factor beta receptor activity	7/4553	16/18639	0.4375	1.79103063913903	0.0713514606432887	0.2701925036094
GO:0008296	3'-5'-DNA exonuclease activity	7/4553	16/18639	0.4375	1.79103063913903	0.0713514606432887	0.2701925036094
GO:0015923	mannosidase activity	7/4553	16/18639	0.4375	1.79103063913903	0.0713514606432887	0.2701925036094
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0004382	GDP phosphatase activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0004862	cAMP-dependent protein kinase inhibitor activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0005381	iron ion transmembrane transporter activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0008239	dipeptidyl-peptidase activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0042975	peroxisome proliferator activated receptor binding	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0050815	phosphoserine residue binding	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0098505	G-rich strand telomeric DNA binding	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0140999	histone H3K4 trimethyltransferase activity	5/4553	10/18639	0.5	2.04689215901603	0.0715623578892102	0.2701925036094
GO:0005035	death receptor activity	6/4553	13/18639	0.461538461538462	1.8894389160148	0.0726896950597933	0.270699602094257
GO:0031994	insulin-like growth factor I binding	6/4553	13/18639	0.461538461538462	1.8894389160148	0.0726896950597933	0.270699602094257
GO:0046975	histone H3K36 methyltransferase activity	6/4553	13/18639	0.461538461538462	1.8894389160148	0.0726896950597933	0.270699602094257
GO:0070123	transforming growth factor beta receptor activity, type III	6/4553	13/18639	0.461538461538462	1.8894389160148	0.0726896950597933	0.270699602094257
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	6/4553	13/18639	0.461538461538462	1.8894389160148	0.0726896950597933	0.270699602094257
GO:0016417	S-acyltransferase activity	11/4553	29/18639	0.379310344827586	1.55281474132251	0.0741916729614902	0.274046748635532
GO:0043236	laminin binding	11/4553	29/18639	0.379310344827586	1.55281474132251	0.0741916729614902	0.274046748635532
GO:0051861	glycolipid binding	11/4553	29/18639	0.379310344827586	1.55281474132251	0.0741916729614902	0.274046748635532
GO:0001098	basal transcription machinery binding	20/4553	60/18639	0.333333333333333	1.36459477267736	0.0757130928608242	0.277973936855805
GO:0001099	basal RNA polymerase II transcription machinery binding	20/4553	60/18639	0.333333333333333	1.36459477267736	0.0757130928608242	0.277973936855805
GO:0051018	protein kinase A binding	18/4553	53/18639	0.339622641509434	1.39034184385995	0.0758666944316651	0.277973936855805
GO:0004713	protein tyrosine kinase activity	42/4553	140/18639	0.3	1.22813529540962	0.0769068421026892	0.281029559747897
GO:0016741	transferase activity, transferring one-carbon groups	62/4553	215/18639	0.288372093023256	1.18053315217669	0.0776035968365186	0.282817386332018
GO:0004435	phosphatidylinositol phospholipase C activity	10/4553	26/18639	0.384615384615385	1.57453243001233	0.0795653964112338	0.286915650093935
GO:0008157	protein phosphatase 1 binding	10/4553	26/18639	0.384615384615385	1.57453243001233	0.0795653964112338	0.286915650093935
GO:0043548	phosphatidylinositol 3-kinase binding	10/4553	26/18639	0.384615384615385	1.57453243001233	0.0795653964112338	0.286915650093935
GO:0008168	methyltransferase activity	59/4553	204/18639	0.28921568627451	1.18398664099947	0.0795701509431456	0.286915650093935
GO:0004712	protein serine/threonine/tyrosine kinase activity	15/4553	43/18639	0.348837209302326	1.42806429698793	0.0813362290756424	0.292509974221901
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	49/4553	167/18639	0.293413173652695	1.20117024900342	0.0835389237954053	0.29964092929773
GO:0019905	syntaxin binding	20/4553	61/18639	0.327868852459016	1.34222436656789	0.0877454429930195	0.312795694111759
GO:0004532	RNA exonuclease activity	14/4553	40/18639	0.35	1.43282451131122	0.088124392178221	0.312795694111759
GO:0032451	demethylase activity	14/4553	40/18639	0.35	1.43282451131122	0.088124392178221	0.312795694111759
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	14/4553	40/18639	0.35	1.43282451131122	0.088124392178221	0.312795694111759
GO:0005518	collagen binding	23/4553	72/18639	0.319444444444444	1.30773665714913	0.0910464824588752	0.322328196341421
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/4553	30/18639	0.366666666666667	1.50105424994509	0.092257557942624	0.325769563408799
GO:0016597	amino acid binding	17/4553	51/18639	0.333333333333333	1.36459477267736	0.0962873809414141	0.338440279506415
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	7/4553	17/18639	0.411764705882353	1.68567589566026	0.0965908061100479	0.338440279506415
GO:1990226	histone methyltransferase binding	7/4553	17/18639	0.411764705882353	1.68567589566026	0.0965908061100479	0.338440279506415
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	10/4553	27/18639	0.37037037037037	1.51621641408595	0.099769349598897	0.347789318422753
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	10/4553	27/18639	0.37037037037037	1.51621641408595	0.099769349598897	0.347789318422753
GO:0004705	JUN kinase activity	6/4553	14/18639	0.428571428571429	1.75447899344231	0.101768424895906	0.349396380687958
GO:0008174	mRNA methyltransferase activity	6/4553	14/18639	0.428571428571429	1.75447899344231	0.101768424895906	0.349396380687958
GO:0008474	palmitoyl-(protein) hydrolase activity	6/4553	14/18639	0.428571428571429	1.75447899344231	0.101768424895906	0.349396380687958
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	6/4553	14/18639	0.428571428571429	1.75447899344231	0.101768424895906	0.349396380687958
GO:0098599	palmitoyl hydrolase activity	6/4553	14/18639	0.428571428571429	1.75447899344231	0.101768424895906	0.349396380687958
GO:0098847	sequence-specific single stranded DNA binding	6/4553	14/18639	0.428571428571429	1.75447899344231	0.101768424895906	0.349396380687958
GO:0019208	phosphatase regulator activity	35/4553	117/18639	0.299145299145299	1.22463633445404	0.102384955507168	0.35062988531726
GO:0016176	superoxide-generating NADPH oxidase activator activity	5/4553	11/18639	0.454545454545455	1.86081105365094	0.105575754492033	0.35618750834812
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	5/4553	11/18639	0.454545454545455	1.86081105365094	0.105575754492033	0.35618750834812
GO:0032794	GTPase activating protein binding	5/4553	11/18639	0.454545454545455	1.86081105365094	0.105575754492033	0.35618750834812
GO:0034713	type I transforming growth factor beta receptor binding	5/4553	11/18639	0.454545454545455	1.86081105365094	0.105575754492033	0.35618750834812
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/4553	11/18639	0.454545454545455	1.86081105365094	0.105575754492033	0.35618750834812
GO:0050786	RAGE receptor binding	5/4553	11/18639	0.454545454545455	1.86081105365094	0.105575754492033	0.35618750834812
GO:0004622	lysophospholipase activity	9/4553	24/18639	0.375	1.53516911926202	0.107905542413281	0.359597198800248
GO:0019957	C-C chemokine binding	9/4553	24/18639	0.375	1.53516911926202	0.107905542413281	0.359597198800248
GO:0042625	ATPase-coupled ion transmembrane transporter activity	9/4553	24/18639	0.375	1.53516911926202	0.107905542413281	0.359597198800248
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	9/4553	24/18639	0.375	1.53516911926202	0.107905542413281	0.359597198800248
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9/4553	24/18639	0.375	1.53516911926202	0.107905542413281	0.359597198800248
GO:0004715	non-membrane spanning protein tyrosine kinase activity	15/4553	45/18639	0.333333333333333	1.36459477267736	0.113579666526926	0.375750207466504
GO:0046915	transition metal ion transmembrane transporter activity	15/4553	45/18639	0.333333333333333	1.36459477267736	0.113579666526926	0.375750207466504
GO:0141110	transporter inhibitor activity	15/4553	45/18639	0.333333333333333	1.36459477267736	0.113579666526926	0.375750207466504
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	13/4553	38/18639	0.342105263157895	1.40050516143202	0.114141977282435	0.375786268202799
GO:0042887	amide transmembrane transporter activity	13/4553	38/18639	0.342105263157895	1.40050516143202	0.114141977282435	0.375786268202799
GO:0019888	protein phosphatase regulator activity	32/4553	107/18639	0.299065420560748	1.22430932875725	0.114530803737244	0.376157796370756
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	8/4553	21/18639	0.380952380952381	1.55953688305983	0.116682619218373	0.382303870179428
GO:0016757	glycosyltransferase activity	74/4553	267/18639	0.277153558052434	1.13460688964185	0.118310947056013	0.386709402487639
GO:0030170	pyridoxal phosphate binding	18/4553	56/18639	0.321428571428571	1.31585924508174	0.11866608844769	0.38694229319187
GO:0031406	carboxylic acid binding	53/4553	187/18639	0.283422459893048	1.16027042168823	0.122544708321296	0.398119026960587
GO:0097718	disordered domain specific binding	10/4553	28/18639	0.357142857142857	1.4620658278686	0.122677909995192	0.398119026960587
GO:0000175	3'-5'-RNA exonuclease activity	12/4553	35/18639	0.342857142857143	1.40358319475385	0.124308648090014	0.400550088290044
GO:0005154	epidermal growth factor receptor binding	12/4553	35/18639	0.342857142857143	1.40358319475385	0.124308648090014	0.400550088290044
GO:0043015	gamma-tubulin binding	12/4553	35/18639	0.342857142857143	1.40358319475385	0.124308648090014	0.400550088290044
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	19/4553	60/18639	0.316666666666667	1.29636503404349	0.125018128834811	0.401886107551528
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	7/4553	18/18639	0.388888888888889	1.59202723479025	0.126074864337519	0.403380375802908
GO:0050811	GABA receptor binding	7/4553	18/18639	0.388888888888889	1.59202723479025	0.126074864337519	0.403380375802908
GO:0030276	clathrin binding	15/4553	46/18639	0.326086956521739	1.3349296689235	0.132182833677867	0.421932558086493
GO:0003707	nuclear steroid receptor activity	9/4553	25/18639	0.36	1.47376235449154	0.133676947328703	0.42471253894877
GO:0017025	TBP-class protein binding	9/4553	25/18639	0.36	1.47376235449154	0.133676947328703	0.42471253894877
GO:0070279	vitamin B6 binding	18/4553	57/18639	0.315789473684211	1.29277399516802	0.135607470388899	0.428963043107963
GO:0005041	low-density lipoprotein particle receptor activity	6/4553	15/18639	0.4	1.63751372721283	0.135958939561732	0.428963043107963
GO:0061578	K63-linked deubiquitinase activity	6/4553	15/18639	0.4	1.63751372721283	0.135958939561732	0.428963043107963
GO:0004620	phospholipase activity	32/4553	109/18639	0.293577981651376	1.20184493740391	0.138484227928608	0.435921484218689
GO:0043177	organic acid binding	53/4553	189/18639	0.28042328042328	1.14799242780793	0.141023723663849	0.442892477773792
GO:0008200	ion channel inhibitor activity	14/4553	43/18639	0.325581395348837	1.33286001052207	0.14398010451073	0.445111669867823
GO:0140035	ubiquitin-like protein reader activity	8/4553	22/18639	0.363636363636364	1.48864884292075	0.145891976251634	0.445111669867823
GO:0140517	protein-RNA adaptor activity	8/4553	22/18639	0.363636363636364	1.48864884292075	0.145891976251634	0.445111669867823
GO:0005025	transforming growth factor beta receptor activity, type I	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0005026	transforming growth factor beta receptor activity, type II	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0016361	activin receptor activity, type I	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0016362	activin receptor activity, type II	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0016840	carbon-nitrogen lyase activity	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0017002	activin receptor activity	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0043047	single-stranded telomeric DNA binding	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0097371	MDM2/MDM4 family protein binding	5/4553	12/18639	0.416666666666667	1.70574346584669	0.145975727388787	0.445111669867823
GO:0003925	G protein activity	17/4553	54/18639	0.314814814814815	1.28878395197306	0.147237613974226	0.446959616585458
GO:0050661	NADP binding	17/4553	54/18639	0.314814814814815	1.28878395197306	0.147237613974226	0.446959616585458
GO:0005504	fatty acid binding	15/4553	47/18639	0.319148936170213	1.30652691001023	0.152397944300981	0.46159644018275
GO:0005229	intracellularly calcium-gated chloride channel activity	7/4553	19/18639	0.368421052631579	1.50823632769602	0.159503905706269	0.477810601049768
GO:0005520	insulin-like growth factor binding	7/4553	19/18639	0.368421052631579	1.50823632769602	0.159503905706269	0.477810601049768
GO:0008574	plus-end-directed microtubule motor activity	7/4553	19/18639	0.368421052631579	1.50823632769602	0.159503905706269	0.477810601049768
GO:0042800	histone H3K4 methyltransferase activity	7/4553	19/18639	0.368421052631579	1.50823632769602	0.159503905706269	0.477810601049768
GO:0141147	intracellularly calcium-gated channel activity	7/4553	19/18639	0.368421052631579	1.50823632769602	0.159503905706269	0.477810601049768
GO:0019956	chemokine binding	11/4553	33/18639	0.333333333333333	1.36459477267736	0.160732780448957	0.478891640139799
GO:0030296	protein tyrosine kinase activator activity	11/4553	33/18639	0.333333333333333	1.36459477267736	0.160732780448957	0.478891640139799
GO:0004112	cyclic-nucleotide phosphodiesterase activity	9/4553	26/18639	0.346153846153846	1.4170791870111	0.162324238990893	0.478891640139799
GO:0034237	protein kinase A regulatory subunit binding	9/4553	26/18639	0.346153846153846	1.4170791870111	0.162324238990893	0.478891640139799
GO:0050681	nuclear androgen receptor binding	9/4553	26/18639	0.346153846153846	1.4170791870111	0.162324238990893	0.478891640139799
GO:0070412	R-SMAD binding	9/4553	26/18639	0.346153846153846	1.4170791870111	0.162324238990893	0.478891640139799
GO:0097602	cullin family protein binding	9/4553	26/18639	0.346153846153846	1.4170791870111	0.162324238990893	0.478891640139799
GO:1902936	phosphatidylinositol bisphosphate binding	32/4553	111/18639	0.288288288288288	1.1801900736669	0.165218508683926	0.485761460113192
GO:0001046	core promoter sequence-specific DNA binding	14/4553	44/18639	0.318181818181818	1.30256773755566	0.166078386216249	0.485761460113192
GO:0016248	channel inhibitor activity	14/4553	44/18639	0.318181818181818	1.30256773755566	0.166078386216249	0.485761460113192
GO:0016790	thiolester hydrolase activity	14/4553	44/18639	0.318181818181818	1.30256773755566	0.166078386216249	0.485761460113192
GO:0001618	virus receptor activity	24/4553	81/18639	0.296296296296296	1.21297313126876	0.167345662912056	0.488419996893218
GO:0019213	deacetylase activity	12/4553	37/18639	0.324324324324324	1.32771383287527	0.171660890202274	0.499944002875426
GO:0031435	mitogen-activated protein kinase kinase kinase binding	6/4553	16/18639	0.375	1.53516911926202	0.174723426912797	0.506697938047111
GO:0034450	ubiquitin-ubiquitin ligase activity	6/4553	16/18639	0.375	1.53516911926202	0.174723426912797	0.506697938047111
GO:0005158	insulin receptor binding	8/4553	23/18639	0.347826086956522	1.42392498018507	0.178273668926019	0.511551601570871
GO:0016493	C-C chemokine receptor activity	8/4553	23/18639	0.347826086956522	1.42392498018507	0.178273668926019	0.511551601570871
GO:0043274	phospholipase binding	8/4553	23/18639	0.347826086956522	1.42392498018507	0.178273668926019	0.511551601570871
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	8/4553	23/18639	0.347826086956522	1.42392498018507	0.178273668926019	0.511551601570871
GO:0140103	catalytic activity, acting on a glycoprotein	8/4553	23/18639	0.347826086956522	1.42392498018507	0.178273668926019	0.511551601570871
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/4553	41/18639	0.317073170731707	1.29802917401017	0.181270891357299	0.518500989135224
GO:0030159	signaling receptor complex adaptor activity	16/4553	52/18639	0.307692307692308	1.25962594400987	0.181456325618123	0.518500989135224
GO:0140272	exogenous protein binding	24/4553	82/18639	0.292682926829268	1.19818077600939	0.18447770865089	0.525312157533868
GO:0050840	extracellular matrix binding	20/4553	67/18639	0.298507462686567	1.22202516956181	0.18461080224411	0.525312157533868
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/4553	13/18639	0.384615384615385	1.57453243001233	0.191779497594408	0.538959701486964
GO:0019104	DNA N-glycosylase activity	5/4553	13/18639	0.384615384615385	1.57453243001233	0.191779497594408	0.538959701486964
GO:0035325	Toll-like receptor binding	5/4553	13/18639	0.384615384615385	1.57453243001233	0.191779497594408	0.538959701486964
GO:0035673	oligopeptide transmembrane transporter activity	5/4553	13/18639	0.384615384615385	1.57453243001233	0.191779497594408	0.538959701486964
GO:0097157	pre-mRNA intronic binding	5/4553	13/18639	0.384615384615385	1.57453243001233	0.191779497594408	0.538959701486964
GO:0140666	annealing activity	5/4553	13/18639	0.384615384615385	1.57453243001233	0.191779497594408	0.538959701486964
GO:0005044	scavenger receptor activity	9/4553	27/18639	0.333333333333333	1.36459477267736	0.193601683686891	0.541846190688362
GO:0005385	zinc ion transmembrane transporter activity	9/4553	27/18639	0.333333333333333	1.36459477267736	0.193601683686891	0.541846190688362
GO:0016004	phospholipase activator activity	7/4553	20/18639	0.35	1.43282451131122	0.196433287827445	0.547522640713308
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	7/4553	20/18639	0.35	1.43282451131122	0.196433287827445	0.547522640713308
GO:0001222	transcription corepressor binding	15/4553	49/18639	0.306122448979592	1.25319928103022	0.197387063978249	0.549058302453784
GO:0043531	ADP binding	12/4553	38/18639	0.315789473684211	1.29277399516802	0.198208080780661	0.550219173327986
GO:0140296	general transcription initiation factor binding	16/4553	53/18639	0.30188679245283	1.2358594167644	0.204209782172747	0.564623513547861
GO:0008327	methyl-CpG binding	10/4553	31/18639	0.32258064516129	1.32057558646196	0.206368821458288	0.564623513547861
GO:0048487	beta-tubulin binding	13/4553	42/18639	0.30952380952381	1.26712371748612	0.207130342180408	0.564623513547861
GO:0004090	carbonyl reductase (NADPH) activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0005031	tumor necrosis factor receptor activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0005345	purine nucleobase transmembrane transporter activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0008140	cAMP response element binding protein binding	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0031434	mitogen-activated protein kinase kinase binding	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0032356	oxidized DNA binding	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0035374	chondroitin sulfate binding	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0051880	G-quadruplex DNA binding	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0070513	death domain binding	4/4553	10/18639	0.4	1.63751372721283	0.21085353514003	0.564623513547861
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	8/4553	24/18639	0.333333333333333	1.36459477267736	0.213457732182389	0.569359860987467
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	8/4553	24/18639	0.333333333333333	1.36459477267736	0.213457732182389	0.569359860987467
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	14/4553	46/18639	0.304347826086957	1.24593435766193	0.214989520572683	0.572325618243295
GO:0008484	sulfuric ester hydrolase activity	6/4553	17/18639	0.352941176470588	1.44486505342308	0.217341220077933	0.574100935981052
GO:0017110	nucleoside diphosphate phosphatase activity	6/4553	17/18639	0.352941176470588	1.44486505342308	0.217341220077933	0.574100935981052
GO:0038191	neuropilin binding	6/4553	17/18639	0.352941176470588	1.44486505342308	0.217341220077933	0.574100935981052
GO:0070403	NAD+ binding	6/4553	17/18639	0.352941176470588	1.44486505342308	0.217341220077933	0.574100935981052
GO:0032813	tumor necrosis factor receptor superfamily binding	15/4553	50/18639	0.3	1.22813529540962	0.221965219138212	0.585181032273467
GO:0016776	phosphotransferase activity, phosphate group as acceptor	12/4553	39/18639	0.307692307692308	1.25962594400987	0.226449559200222	0.59382823003461
GO:0035401	histone H3Y41 kinase activity	32/4553	115/18639	0.278260869565217	1.13913998414805	0.226552222757151	0.59382823003461
GO:0140801	histone H2AXY142 kinase activity	32/4553	115/18639	0.278260869565217	1.13913998414805	0.226552222757151	0.59382823003461
GO:0046875	ephrin receptor binding	9/4553	28/18639	0.321428571428571	1.31585924508174	0.22719715543559	0.594375667675066
GO:0004519	endonuclease activity	35/4553	127/18639	0.275590551181102	1.12820827662301	0.233028037608955	0.608462098201161
GO:0008375	acetylglucosaminyltransferase activity	13/4553	43/18639	0.302325581395349	1.23765572405621	0.234495445170603	0.611122928809811
GO:0031072	heat shock protein binding	36/4553	131/18639	0.274809160305344	1.12500943090958	0.234964370999128	0.611176407770632
GO:0005123	death receptor binding	7/4553	21/18639	0.333333333333333	1.36459477267736	0.236308622131982	0.612335840239337
GO:0035613	RNA stem-loop binding	7/4553	21/18639	0.333333333333333	1.36459477267736	0.236308622131982	0.612335840239337
GO:0015101	organic cation transmembrane transporter activity	23/4553	81/18639	0.283950617283951	1.16243258413256	0.237530321813	0.613443269834915
GO:0043425	bHLH transcription factor binding	10/4553	32/18639	0.3125	1.27930759938502	0.238536267800811	0.613443269834915
GO:0071813	lipoprotein particle binding	10/4553	32/18639	0.3125	1.27930759938502	0.238536267800811	0.613443269834915
GO:0071814	protein-lipid complex binding	10/4553	32/18639	0.3125	1.27930759938502	0.238536267800811	0.613443269834915
GO:0005545	1-phosphatidylinositol binding	5/4553	14/18639	0.357142857142857	1.4620658278686	0.241785649093576	0.617142021937349
GO:0019763	immunoglobulin receptor activity	5/4553	14/18639	0.357142857142857	1.4620658278686	0.241785649093576	0.617142021937349
GO:0046030	inositol trisphosphate phosphatase activity	5/4553	14/18639	0.357142857142857	1.4620658278686	0.241785649093576	0.617142021937349
GO:0098821	BMP receptor activity	5/4553	14/18639	0.357142857142857	1.4620658278686	0.241785649093576	0.617142021937349
GO:0030544	Hsp70 protein binding	15/4553	51/18639	0.294117647058824	1.2040542111859	0.247768087781602	0.631229726441726
GO:0008139	nuclear localization sequence binding	8/4553	25/18639	0.32	1.31001098177026	0.251001630937064	0.638274669714959
GO:0008374	O-acyltransferase activity	16/4553	55/18639	0.290909090909091	1.1909190743366	0.253304219329443	0.642930448689072
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	12/4553	40/18639	0.3	1.22813529540962	0.256182337347156	0.646623195933655
GO:0061791	GTPase motor activity	12/4553	40/18639	0.3	1.22813529540962	0.256182337347156	0.646623195933655
GO:1990606	membrane scission GTPase motor activity	12/4553	40/18639	0.3	1.22813529540962	0.256182337347156	0.646623195933655
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	24/4553	86/18639	0.27906976744186	1.14245143759034	0.261195603112324	0.653411946201637
GO:1901682	sulfur compound transmembrane transporter activity	18/4553	63/18639	0.285714285714286	1.16965266229488	0.262715567547199	0.653411946201637
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9/4553	29/18639	0.310344827586207	1.27048478835478	0.262747233428419	0.653411946201637
GO:0097472	cyclin-dependent protein kinase activity	9/4553	29/18639	0.310344827586207	1.27048478835478	0.262747233428419	0.653411946201637
GO:0008308	voltage-gated monoatomic anion channel activity	6/4553	18/18639	0.333333333333333	1.36459477267736	0.26297439794814	0.653411946201637
GO:0015172	acidic amino acid transmembrane transporter activity	6/4553	18/18639	0.333333333333333	1.36459477267736	0.26297439794814	0.653411946201637
GO:0017075	syntaxin-1 binding	6/4553	18/18639	0.333333333333333	1.36459477267736	0.26297439794814	0.653411946201637
GO:0070064	proline-rich region binding	6/4553	18/18639	0.333333333333333	1.36459477267736	0.26297439794814	0.653411946201637
GO:0019205	nucleobase-containing compound kinase activity	13/4553	44/18639	0.295454545454545	1.20952718487311	0.263186469893396	0.653411946201637
GO:0038187	pattern recognition receptor activity	14/4553	48/18639	0.291666666666667	1.19402042609269	0.269288978248809	0.659624499710183
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0015205	nucleobase transmembrane transporter activity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0019107	myristoyltransferase activity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0019203	carbohydrate phosphatase activity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0019206	nucleoside kinase activity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0042608	T cell receptor binding	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0097493	structural molecule activity conferring elasticity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0140031	phosphorylation-dependent protein binding	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:1990948	ubiquitin ligase inhibitor activity	4/4553	11/18639	0.363636363636364	1.48864884292075	0.271012266938887	0.659624499710183
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	10/4553	33/18639	0.303030303030303	1.24054070243396	0.272363870997268	0.660555082151738
GO:0019239	deaminase activity	10/4553	33/18639	0.303030303030303	1.24054070243396	0.272363870997268	0.660555082151738
GO:0033293	monocarboxylic acid binding	22/4553	79/18639	0.278481012658228	1.14004120248994	0.276782511874616	0.669487948010907
GO:0008093	cytoskeletal anchor activity	7/4553	22/18639	0.318181818181818	1.30256773755566	0.278503056876144	0.669487948010907
GO:0008649	rRNA methyltransferase activity	7/4553	22/18639	0.318181818181818	1.30256773755566	0.278503056876144	0.669487948010907
GO:0033691	sialic acid binding	7/4553	22/18639	0.318181818181818	1.30256773755566	0.278503056876144	0.669487948010907
GO:0050321	tau-protein kinase activity	7/4553	22/18639	0.318181818181818	1.30256773755566	0.278503056876144	0.669487948010907
GO:0016758	hexosyltransferase activity	52/4553	197/18639	0.263959390862944	1.08059281491202	0.283479356435337	0.679403494756275
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	17/4553	60/18639	0.283333333333333	1.15990555677575	0.283624789813882	0.679403494756275
GO:0051087	protein-folding chaperone binding	36/4553	134/18639	0.26865671641791	1.09982265260563	0.284371983765506	0.679998269951552
GO:0051015	actin filament binding	55/4553	209/18639	0.263157894736842	1.07731166264002	0.285278265010818	0.680970709649291
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	12/4553	41/18639	0.292682926829268	1.19818077600939	0.287180177067097	0.684312205144149
GO:0001637	G protein-coupled chemoattractant receptor activity	8/4553	26/18639	0.307692307692308	1.25962594400987	0.290413805135362	0.687211834026907
GO:0004950	chemokine receptor activity	8/4553	26/18639	0.307692307692308	1.25962594400987	0.290413805135362	0.687211834026907
GO:0005112	Notch binding	8/4553	26/18639	0.307692307692308	1.25962594400987	0.290413805135362	0.687211834026907
GO:0019865	immunoglobulin binding	8/4553	26/18639	0.307692307692308	1.25962594400987	0.290413805135362	0.687211834026907
GO:0015929	hexosaminidase activity	5/4553	15/18639	0.333333333333333	1.36459477267736	0.294699003859499	0.693738760380824
GO:0017081	chloride channel regulator activity	5/4553	15/18639	0.333333333333333	1.36459477267736	0.294699003859499	0.693738760380824
GO:0050780	dopamine receptor binding	5/4553	15/18639	0.333333333333333	1.36459477267736	0.294699003859499	0.693738760380824
GO:0035254	glutamate receptor binding	14/4553	49/18639	0.285714285714286	1.16965266229488	0.298049743957032	0.700416898299026
GO:1901505	carbohydrate derivative transmembrane transporter activity	15/4553	53/18639	0.283018867924528	1.15861820321662	0.302457071090905	0.709550753695188
GO:0052689	carboxylic ester hydrolase activity	25/4553	92/18639	0.271739130434783	1.11244139076958	0.305620823492698	0.715740863265545
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	10/4553	34/18639	0.294117647058824	1.2040542111859	0.307519824864769	0.716494908189196
GO:0016831	carboxy-lyase activity	10/4553	34/18639	0.294117647058824	1.2040542111859	0.307519824864769	0.716494908189196
GO:0051427	hormone receptor binding	10/4553	34/18639	0.294117647058824	1.2040542111859	0.307519824864769	0.716494908189196
GO:0015245	fatty acid transmembrane transporter activity	6/4553	19/18639	0.315789473684211	1.29277399516802	0.31073000975208	0.719057730546834
GO:0050145	nucleoside monophosphate kinase activity	6/4553	19/18639	0.315789473684211	1.29277399516802	0.31073000975208	0.719057730546834
GO:0140036	ubiquitin-modified protein reader activity	6/4553	19/18639	0.315789473684211	1.29277399516802	0.31073000975208	0.719057730546834
GO:1990380	K48-linked deubiquitinase activity	6/4553	19/18639	0.315789473684211	1.29277399516802	0.31073000975208	0.719057730546834
GO:0005516	calmodulin binding	54/4553	207/18639	0.260869565217391	1.0679437351388	0.312824922092834	0.722678591207682
GO:0005109	frizzled binding	11/4553	38/18639	0.289473684210526	1.18504282890402	0.313866323863499	0.723857528639507
GO:0035198	miRNA binding	12/4553	42/18639	0.285714285714286	1.16965266229488	0.319200111021772	0.733675803242286
GO:0051879	Hsp90 protein binding	12/4553	42/18639	0.285714285714286	1.16965266229488	0.319200111021772	0.733675803242286
GO:0004602	glutathione peroxidase activity	7/4553	23/18639	0.304347826086957	1.24593435766193	0.322353414104324	0.735959302218079
GO:0042171	lysophosphatidic acid acyltransferase activity	7/4553	23/18639	0.304347826086957	1.24593435766193	0.322353414104324	0.735959302218079
GO:0071617	lysophospholipid acyltransferase activity	7/4553	23/18639	0.304347826086957	1.24593435766193	0.322353414104324	0.735959302218079
GO:0140102	catalytic activity, acting on a rRNA	7/4553	23/18639	0.304347826086957	1.24593435766193	0.322353414104324	0.735959302218079
GO:0051287	NAD binding	15/4553	54/18639	0.277777777777778	1.13716231056446	0.331018227849142	0.742575497820467
GO:0004683	calcium/calmodulin-dependent protein kinase activity	8/4553	27/18639	0.296296296296296	1.21297313126876	0.331176803639981	0.742575497820467
GO:0004875	complement receptor activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0005049	nuclear export signal receptor activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0005095	GTPase inhibitor activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0005165	neurotrophin receptor binding	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0008504	monoamine transmembrane transporter activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0035197	siRNA binding	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0035251	UDP-glucosyltransferase activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0045295	gamma-catenin binding	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0070679	inositol 1,4,5 trisphosphate binding	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0097677	STAT family protein binding	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:1990459	transferrin receptor binding	4/4553	12/18639	0.333333333333333	1.36459477267736	0.333530536713937	0.742575497820467
GO:0061980	regulatory RNA binding	16/4553	58/18639	0.275862068965517	1.12931981187091	0.333968290655867	0.742575497820467
GO:0015179	L-amino acid transmembrane transporter activity	17/4553	62/18639	0.274193548387097	1.12248924849266	0.336558380270575	0.747115752945918
GO:0050660	flavin adenine dinucleotide binding	23/4553	86/18639	0.267441860465116	1.09484929435741	0.347000646294784	0.765281455971535
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0005159	insulin-like growth factor receptor binding	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0022858	alanine transmembrane transporter activity	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0140327	flippase activity	5/4553	16/18639	0.3125	1.27930759938502	0.349233357017091	0.765281455971535
GO:0045296	cadherin binding	85/4553	334/18639	0.254491017964072	1.04183133842133	0.35073822903317	0.766613829640831
GO:0008238	exopeptidase activity	27/4553	102/18639	0.264705882352941	1.08364879006731	0.35096627270424	0.766613829640831
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	12/4553	43/18639	0.27906976744186	1.14245143759034	0.351989013931903	0.767617641582694
GO:0005048	signal sequence binding	14/4553	51/18639	0.274509803921569	1.12378393044018	0.357859282570437	0.775776292720259
GO:0016830	carbon-carbon lyase activity	14/4553	51/18639	0.274509803921569	1.12378393044018	0.357859282570437	0.775776292720259
GO:0001614	purinergic nucleotide receptor activity	6/4553	20/18639	0.3	1.22813529540962	0.359714319148352	0.775776292720259
GO:0005326	neurotransmitter transmembrane transporter activity	6/4553	20/18639	0.3	1.22813529540962	0.359714319148352	0.775776292720259
GO:0016502	nucleotide receptor activity	6/4553	20/18639	0.3	1.22813529540962	0.359714319148352	0.775776292720259
GO:0016505	peptidase activator activity involved in apoptotic process	6/4553	20/18639	0.3	1.22813529540962	0.359714319148352	0.775776292720259
GO:0043024	ribosomal small subunit binding	6/4553	20/18639	0.3	1.22813529540962	0.359714319148352	0.775776292720259
GO:0005507	copper ion binding	17/4553	63/18639	0.26984126984127	1.10467195883405	0.363848115407474	0.783451787204404
GO:0008173	RNA methyltransferase activity	18/4553	67/18639	0.26865671641791	1.09982265260563	0.365329231241819	0.784163373515904
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	18/4553	67/18639	0.26865671641791	1.09982265260563	0.365329231241819	0.784163373515904
GO:0030552	cAMP binding	7/4553	24/18639	0.291666666666667	1.19402042609269	0.367192812542767	0.784391510019723
GO:0048027	mRNA 5'-UTR binding	7/4553	24/18639	0.291666666666667	1.19402042609269	0.367192812542767	0.784391510019723
GO:0060229	lipase activator activity	7/4553	24/18639	0.291666666666667	1.19402042609269	0.367192812542767	0.784391510019723
GO:0003725	double-stranded RNA binding	20/4553	75/18639	0.266666666666667	1.09167581814188	0.367737472415703	0.784391510019723
GO:0072341	modified amino acid binding	24/4553	91/18639	0.263736263736264	1.07967938057989	0.370952644913934	0.790013210965144
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/4553	28/18639	0.285714285714286	1.16965266229488	0.372768662921738	0.792642258287564
GO:0070717	poly-purine tract binding	9/4553	32/18639	0.28125	1.15137683944652	0.377055240660954	0.798022194131802
GO:0120015	sterol transfer activity	9/4553	32/18639	0.28125	1.15137683944652	0.377055240660954	0.798022194131802
GO:0140142	nucleocytoplasmic carrier activity	9/4553	32/18639	0.28125	1.15137683944652	0.377055240660954	0.798022194131802
GO:0030246	carbohydrate binding	71/4553	280/18639	0.253571428571429	1.0380667377867	0.380063031436852	0.803140948602217
GO:0043014	alpha-tubulin binding	12/4553	44/18639	0.272727272727273	1.11648663219056	0.385289967946343	0.812926046920844
GO:0098531	ligand-modulated transcription factor activity	16/4553	60/18639	0.266666666666667	1.09167581814188	0.390690210702751	0.823045992562364
GO:0005172	vascular endothelial growth factor receptor binding	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0008035	high-density lipoprotein particle binding	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0008253	5'-nucleotidase activity	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0009982	pseudouridine synthase activity	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0032396	inhibitory MHC class I receptor activity	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0043560	insulin receptor substrate binding	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0089720	caspase binding	4/4553	13/18639	0.307692307692308	1.25962594400987	0.396530998544838	0.823889864354595
GO:0004550	nucleoside diphosphate kinase activity	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0015278	intracellularly gated calcium channel activity	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0016805	dipeptidase activity	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0030169	low-density lipoprotein particle binding	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0032183	SUMO binding	5/4553	17/18639	0.294117647058824	1.2040542111859	0.404188414075073	0.830933345979373
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	6/4553	21/18639	0.285714285714286	1.16965266229488	0.409076597954901	0.833440064293766
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/4553	21/18639	0.285714285714286	1.16965266229488	0.409076597954901	0.833440064293766
GO:0008373	sialyltransferase activity	6/4553	21/18639	0.285714285714286	1.16965266229488	0.409076597954901	0.833440064293766
GO:0015174	basic amino acid transmembrane transporter activity	6/4553	21/18639	0.285714285714286	1.16965266229488	0.409076597954901	0.833440064293766
GO:0072542	protein phosphatase activator activity	6/4553	21/18639	0.285714285714286	1.16965266229488	0.409076597954901	0.833440064293766
GO:0140312	cargo adaptor activity	6/4553	21/18639	0.285714285714286	1.16965266229488	0.409076597954901	0.833440064293766
GO:0015296	monoatomic anion:monoatomic cation symporter activity	7/4553	25/18639	0.28	1.14625960904898	0.412378272056097	0.836416048828065
GO:0019211	phosphatase activator activity	7/4553	25/18639	0.28	1.14625960904898	0.412378272056097	0.836416048828065
GO:0120020	cholesterol transfer activity	7/4553	25/18639	0.28	1.14625960904898	0.412378272056097	0.836416048828065
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	8/4553	29/18639	0.275862068965517	1.12931981187091	0.414681588443002	0.838199884472802
GO:0106222	lncRNA binding	8/4553	29/18639	0.275862068965517	1.12931981187091	0.414681588443002	0.838199884472802
GO:0051213	dioxygenase activity	24/4553	93/18639	0.258064516129032	1.05646046916957	0.417247836249337	0.838199884472802
GO:0042805	actinin binding	10/4553	37/18639	0.27027027027027	1.10642819406272	0.417475297961983	0.838199884472802
GO:0017080	sodium channel regulator activity	11/4553	41/18639	0.268292682926829	1.0983323780086	0.418291302494014	0.838199884472802
GO:0140318	protein transporter activity	11/4553	41/18639	0.268292682926829	1.0983323780086	0.418291302494014	0.838199884472802
GO:0140303	intramembrane lipid transporter activity	12/4553	45/18639	0.266666666666667	1.09167581814188	0.418848208169983	0.838199884472802
GO:0060590	ATPase regulator activity	13/4553	49/18639	0.26530612244898	1.08610604355953	0.419205877274128	0.838199884472802
GO:0160215	deacylase activity	17/4553	65/18639	0.261538461538462	1.07068205240839	0.419357086814727	0.838199884472802
GO:0004864	protein phosphatase inhibitor activity	14/4553	53/18639	0.264150943396226	1.08137698966885	0.419407425686318	0.838199884472802
GO:0141108	transporter regulator activity	43/4553	170/18639	0.252941176470588	1.03548662161988	0.42501406294496	0.848161299844775
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	33/4553	130/18639	0.253846153846154	1.03919140380814	0.432789789377945	0.859611472743759
GO:0031491	nucleosome binding	19/4553	74/18639	0.256756756756757	1.05110678435958	0.44531097820736	0.859611472743759
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	14/4553	54/18639	0.259259259259259	1.06135148986017	0.45034364492933	0.859611472743759
GO:0019894	kinesin binding	11/4553	42/18639	0.261904761904762	1.07218160710364	0.453452693016422	0.859611472743759
GO:0000146	microfilament motor activity	10/4553	38/18639	0.263157894736842	1.07731166264002	0.454478502997156	0.859611472743759
GO:0001965	G-protein alpha-subunit binding	8/4553	30/18639	0.266666666666667	1.09167581814188	0.456437373764288	0.859611472743759
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0005522	profilin binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0008190	eukaryotic initiation factor 4E binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0015279	store-operated calcium channel activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0015643	toxic substance binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0016783	sulfurtransferase activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0016868	intramolecular phosphotransferase activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0030957	Tat protein binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0031419	cobalamin binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0031996	thioesterase binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0035256	G protein-coupled glutamate receptor binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0043208	glycosphingolipid binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0043295	glutathione binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0045322	unmethylated CpG binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0047429	nucleoside triphosphate diphosphatase activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0050308	sugar-phosphatase activity	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/4553	10/18639	0.3	1.22813529540962	0.457160571333632	0.859611472743759
GO:0030247	polysaccharide binding	7/4553	26/18639	0.269230769230769	1.10217270100863	0.457312549342683	0.859611472743759
GO:0016853	isomerase activity	45/4553	180/18639	0.25	1.02344607950802	0.457401045448662	0.859611472743759
GO:0008970	phospholipase A1 activity	6/4553	22/18639	0.272727272727273	1.11648663219056	0.458041675859434	0.859611472743759
GO:0015377	chloride:monoatomic cation symporter activity	6/4553	22/18639	0.272727272727273	1.11648663219056	0.458041675859434	0.859611472743759
GO:0031683	G-protein beta/gamma-subunit complex binding	6/4553	22/18639	0.272727272727273	1.11648663219056	0.458041675859434	0.859611472743759
GO:0034062	5'-3' RNA polymerase activity	6/4553	22/18639	0.272727272727273	1.11648663219056	0.458041675859434	0.859611472743759
GO:0097747	RNA polymerase activity	6/4553	22/18639	0.272727272727273	1.11648663219056	0.458041675859434	0.859611472743759
GO:0005161	platelet-derived growth factor receptor binding	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0005313	L-glutamate transmembrane transporter activity	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0008494	translation activator activity	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0015926	glucosidase activity	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0016530	metallochaperone activity	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0030983	mismatched DNA binding	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0031404	chloride ion binding	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0071933	Arp2/3 complex binding	4/4553	14/18639	0.285714285714286	1.16965266229488	0.458429138325343	0.859611472743759
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/4553	18/18639	0.277777777777778	1.13716231056446	0.458501497200816	0.859611472743759
GO:0031690	adrenergic receptor binding	5/4553	18/18639	0.277777777777778	1.13716231056446	0.458501497200816	0.859611472743759
GO:0032393	MHC class I receptor activity	5/4553	18/18639	0.277777777777778	1.13716231056446	0.458501497200816	0.859611472743759
GO:0099106	ion channel regulator activity	40/4553	160/18639	0.25	1.02344607950802	0.463216828088386	0.867258978962184
GO:0004879	nuclear receptor activity	15/4553	59/18639	0.254237288135593	1.04079262322849	0.479035304877659	0.894417973353767
GO:0015459	potassium channel regulator activity	15/4553	59/18639	0.254237288135593	1.04079262322849	0.479035304877659	0.894417973353767
GO:0098632	cell-cell adhesion mediator activity	14/4553	55/18639	0.254545454545455	1.04205419004453	0.481137725280409	0.895995541260144
GO:0005178	integrin binding	40/4553	161/18639	0.248447204968944	1.01708927156076	0.481194964198404	0.895995541260144
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	10/4553	39/18639	0.256410256410256	1.04968828667489	0.4911232887662	0.913234710216003
GO:0051117	ATPase binding	21/4553	84/18639	0.25	1.02344607950802	0.493277907100236	0.915991535936814
GO:0048306	calcium-dependent protein binding	20/4553	80/18639	0.25	1.02344607950802	0.495485671958441	0.916900120644881
GO:0005164	tumor necrosis factor receptor binding	8/4553	31/18639	0.258064516129032	1.05646046916957	0.497599319580026	0.916900120644881
GO:0017147	Wnt-protein binding	8/4553	31/18639	0.258064516129032	1.05646046916957	0.497599319580026	0.916900120644881
GO:0072349	modified amino acid transmembrane transporter activity	8/4553	31/18639	0.258064516129032	1.05646046916957	0.497599319580026	0.916900120644881
GO:0140098	catalytic activity, acting on RNA	95/4553	387/18639	0.245478036175711	1.00493413491743	0.497696955629159	0.916900120644881
GO:0098631	cell adhesion mediator activity	19/4553	76/18639	0.25	1.02344607950802	0.497803440408813	0.916900120644881
GO:0001671	ATPase activator activity	7/4553	27/18639	0.259259259259259	1.06135148986017	0.501460060338628	0.922388747964305
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/4553	19/18639	0.263157894736842	1.07731166264002	0.511277028432507	0.926780530079363
GO:0008301	DNA binding, bending	5/4553	19/18639	0.263157894736842	1.07731166264002	0.511277028432507	0.926780530079363
GO:0097001	ceramide binding	5/4553	19/18639	0.263157894736842	1.07731166264002	0.511277028432507	0.926780530079363
GO:0120227	acyl-CoA binding	5/4553	19/18639	0.263157894736842	1.07731166264002	0.511277028432507	0.926780530079363
GO:0019212	phosphatase inhibitor activity	14/4553	56/18639	0.25	1.02344607950802	0.511614091559644	0.926780530079363
GO:0170055	lipid transmembrane transporter activity	14/4553	56/18639	0.25	1.02344607950802	0.511614091559644	0.926780530079363
GO:0003924	GTPase activity	81/4553	331/18639	0.244712990936556	1.0018022047148	0.514001604595067	0.926780530079363
GO:0005080	protein kinase C binding	13/4553	52/18639	0.25	1.02344607950802	0.51499059763389	0.926780530079363
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0005523	tropomyosin binding	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0008252	nucleotidase activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0050700	CARD domain binding	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0051371	muscle alpha-actinin binding	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0140776	protein-containing complex destabilizing activity	4/4553	15/18639	0.266666666666667	1.09167581814188	0.517967369040195	0.926780530079363
GO:0000099	sulfur amino acid transmembrane transporter activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0001851	complement component C3b binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0004016	adenylate cyclase activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0005225	volume-sensitive anion channel activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0008199	ferric iron binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0034056	estrogen response element binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0043522	leucine zipper domain binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0047676	arachidonate-CoA ligase activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0048407	platelet-derived growth factor binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0070990	snRNP binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0140537	transcription regulator activator activity	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:1900750	oligopeptide binding	3/4553	11/18639	0.272727272727273	1.11648663219056	0.526966185481663	0.926780530079363
GO:0015297	antiporter activity	33/4553	135/18639	0.244444444444444	1.00070283329673	0.531469304979014	0.931964729595818
GO:0004190	aspartic-type endopeptidase activity	9/4553	36/18639	0.25	1.02344607950802	0.532110227074326	0.931964729595818
GO:0055106	ubiquitin-protein transferase regulator activity	9/4553	36/18639	0.25	1.02344607950802	0.532110227074326	0.931964729595818
GO:0016247	channel regulator activity	41/4553	168/18639	0.244047619047619	0.999078315710207	0.532648954038989	0.931964729595818
GO:0022884	macromolecule transmembrane transporter activity	8/4553	32/18639	0.25	1.02344607950802	0.537780679219716	0.938534015078711
GO:0051059	NF-kappaB binding	8/4553	32/18639	0.25	1.02344607950802	0.537780679219716	0.938534015078711
GO:0016504	peptidase activator activity	14/4553	57/18639	0.245614035087719	1.00549088513068	0.541609705116712	0.944007708534628
GO:0016866	intramolecular transferase activity	7/4553	28/18639	0.25	1.02344607950802	0.544357192810925	0.944509061127496
GO:0051537	2 iron, 2 sulfur cluster binding	7/4553	28/18639	0.25	1.02344607950802	0.544357192810925	0.944509061127496
GO:0051959	dynein light intermediate chain binding	7/4553	28/18639	0.25	1.02344607950802	0.544357192810925	0.944509061127496
GO:0033218	amide binding	60/4553	247/18639	0.242914979757085	0.994441534744632	0.544694862864344	0.944509061127496
GO:0043021	ribonucleoprotein complex binding	43/4553	177/18639	0.242937853107345	0.994535173307225	0.545709705474707	0.944509061127496
GO:0005246	calcium channel regulator activity	13/4553	53/18639	0.245283018867925	1.00413577612107	0.54605512851685	0.944509061127496
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/4553	24/18639	0.25	1.02344607950802	0.552177929947786	0.949077576946826
GO:0004806	triacylglycerol lipase activity	6/4553	24/18639	0.25	1.02344607950802	0.552177929947786	0.949077576946826
GO:0015295	solute:proton symporter activity	6/4553	24/18639	0.25	1.02344607950802	0.552177929947786	0.949077576946826
GO:0030215	semaphorin receptor binding	6/4553	24/18639	0.25	1.02344607950802	0.552177929947786	0.949077576946826
GO:0070300	phosphatidic acid binding	6/4553	24/18639	0.25	1.02344607950802	0.552177929947786	0.949077576946826
GO:0008009	chemokine activity	11/4553	45/18639	0.244444444444444	1.00070283329673	0.556269710383486	0.954906316439157
GO:0001972	retinoic acid binding	5/4553	20/18639	0.25	1.02344607950802	0.561797931527226	0.956356940675008
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/4553	20/18639	0.25	1.02344607950802	0.561797931527226	0.956356940675008
GO:0052745	inositol phosphate phosphatase activity	5/4553	20/18639	0.25	1.02344607950802	0.561797931527226	0.956356940675008
GO:0061608	nuclear import signal receptor activity	5/4553	20/18639	0.25	1.02344607950802	0.561797931527226	0.956356940675008
GO:0140939	histone H4 methyltransferase activity	5/4553	20/18639	0.25	1.02344607950802	0.561797931527226	0.956356940675008
GO:0015175	neutral L-amino acid transmembrane transporter activity	10/4553	41/18639	0.24390243902439	0.998483980007821	0.562233970540622	0.956356940675008
GO:0140828	metal cation:monoatomic cation antiporter activity	10/4553	41/18639	0.24390243902439	0.998483980007821	0.562233970540622	0.956356940675008
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	22/4553	91/18639	0.241758241758242	0.989706098864895	0.562728001776491	0.956356940675008
GO:0043022	ribosome binding	27/4553	112/18639	0.241071428571429	0.986894433811302	0.56795460630291	0.963339901574343
GO:0030551	cyclic nucleotide binding	9/4553	37/18639	0.243243243243243	0.995785374656449	0.568957168574722	0.963339901574343
GO:0070001	aspartic-type peptidase activity	9/4553	37/18639	0.243243243243243	0.995785374656449	0.568957168574722	0.963339901574343
GO:0005149	interleukin-1 receptor binding	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0015562	efflux transmembrane transporter activity	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0016722	oxidoreductase activity, acting on metal ions	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0022841	potassium ion leak channel activity	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0030275	LRR domain binding	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0097027	ubiquitin-protein transferase activator activity	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0140328	floppase activity	4/4553	16/18639	0.25	1.02344607950802	0.574212039714564	0.963855923806589
GO:0015485	cholesterol binding	13/4553	54/18639	0.240740740740741	0.985540669155868	0.576402672093381	0.964384972559598
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	13/4553	54/18639	0.240740740740741	0.985540669155868	0.576402672093381	0.964384972559598
GO:0140416	transcription regulator inhibitor activity	8/4553	33/18639	0.242424242424242	0.992432561947168	0.576649855198879	0.964384972559598
GO:0019842	vitamin binding	36/4553	150/18639	0.24	0.982508236327696	0.580124618715257	0.968917276324089
GO:0004540	RNA nuclease activity	29/4553	121/18639	0.239669421487603	0.981154919197768	0.582037366799363	0.968917276324089
GO:0003785	actin monomer binding	7/4553	29/18639	0.241379310344828	0.988154835387051	0.585617612382537	0.968917276324089
GO:0043178	alcohol binding	22/4553	92/18639	0.239130434782609	0.978948423877233	0.585852874237293	0.968917276324089
GO:0004180	carboxypeptidase activity	11/4553	46/18639	0.239130434782609	0.978948423877233	0.588909296794072	0.968917276324089
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0004000	adenosine deaminase activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0004126	cytidine deaminase activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0005436	sodium:phosphate symporter activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0016273	arginine N-methyltransferase activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0016274	protein-arginine N-methyltransferase activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0016801	hydrolase activity, acting on ether bonds	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0016803	ether hydrolase activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0034452	dynactin binding	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0140900	chloride:bicarbonate antiporter activity	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/4553	12/18639	0.25	1.02344607950802	0.591444735070904	0.968917276324089
GO:0016798	hydrolase activity, acting on glycosyl bonds	31/4553	130/18639	0.238461538461538	0.976210106607647	0.595141006466497	0.973802151037017
GO:0001786	phosphatidylserine binding	14/4553	59/18639	0.23728813559322	0.971406448346592	0.599579613445612	0.979888504947685
GO:0005501	retinoid binding	9/4553	38/18639	0.236842105263158	0.969580496376016	0.604485030305691	0.985541981228059
GO:0019840	isoprenoid binding	9/4553	38/18639	0.236842105263158	0.969580496376016	0.604485030305691	0.985541981228059
GO:0070851	growth factor receptor binding	33/4553	139/18639	0.237410071942446	0.97190562946085	0.607394394475927	0.987848185124936
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/4553	21/18639	0.238095238095238	0.974710551912397	0.609523348268578	0.987848185124936
GO:0019200	carbohydrate kinase activity	5/4553	21/18639	0.238095238095238	0.974710551912397	0.609523348268578	0.987848185124936
GO:0061891	calcium ion sensor activity	5/4553	21/18639	0.238095238095238	0.974710551912397	0.609523348268578	0.987848185124936
GO:0070182	DNA polymerase binding	5/4553	21/18639	0.238095238095238	0.974710551912397	0.609523348268578	0.987848185124936
GO:0003727	single-stranded RNA binding	21/4553	89/18639	0.235955056179775	0.965949108749139	0.613050544830618	0.992384670551226
GO:0046982	protein heterodimerization activity	88/4553	369/18639	0.238482384823848	0.976295447118758	0.623083376842357	1
GO:0004549	tRNA-specific ribonuclease activity	4/4553	17/18639	0.235294117647059	0.963243368948722	0.626527001449791	1
GO:0005092	GDP-dissociation inhibitor activity	4/4553	17/18639	0.235294117647059	0.963243368948722	0.626527001449791	1
GO:0031489	myosin V binding	4/4553	17/18639	0.235294117647059	0.963243368948722	0.626527001449791	1
GO:0032977	membrane insertase activity	4/4553	17/18639	0.235294117647059	0.963243368948722	0.626527001449791	1
GO:0048038	quinone binding	4/4553	17/18639	0.235294117647059	0.963243368948722	0.626527001449791	1
GO:0070402	NADPH binding	4/4553	17/18639	0.235294117647059	0.963243368948722	0.626527001449791	1
GO:0044325	transmembrane transporter binding	32/4553	136/18639	0.235294117647059	0.963243368948722	0.62914283331021	1
GO:0008143	poly(A) binding	6/4553	26/18639	0.230769230769231	0.9447194580074	0.638028982632221	1
GO:0050750	low-density lipoprotein particle receptor binding	6/4553	26/18639	0.230769230769231	0.9447194580074	0.638028982632221	1
GO:0051139	metal cation:proton antiporter activity	6/4553	26/18639	0.230769230769231	0.9447194580074	0.638028982632221	1
GO:0015294	solute:monoatomic cation symporter activity	27/4553	116/18639	0.232758620689655	0.952863591266085	0.648815959452524	1
GO:0005343	organic acid:sodium symporter activity	8/4553	35/18639	0.228571428571429	0.935722129835901	0.649412404537303	1
GO:0003964	RNA-directed DNA polymerase activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0005542	folic acid binding	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0008417	fucosyltransferase activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0019855	calcium channel inhibitor activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0045159	myosin II binding	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0061459	L-arginine transmembrane transporter activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0071714	icosanoid transmembrane transporter activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0071837	HMG box domain binding	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/4553	13/18639	0.230769230769231	0.9447194580074	0.649918856028724	1
GO:0019199	transmembrane receptor protein kinase activity	18/4553	78/18639	0.230769230769231	0.9447194580074	0.652077351168865	1
GO:0004407	histone deacetylase activity	5/4553	22/18639	0.227272727272727	0.93040552682547	0.654076781330091	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/4553	22/18639	0.227272727272727	0.93040552682547	0.654076781330091	1
GO:0033558	protein lysine deacetylase activity	5/4553	22/18639	0.227272727272727	0.93040552682547	0.654076781330091	1
GO:0070034	telomerase RNA binding	5/4553	22/18639	0.227272727272727	0.93040552682547	0.654076781330091	1
GO:0140784	metal ion sensor activity	5/4553	22/18639	0.227272727272727	0.93040552682547	0.654076781330091	1
GO:0016411	acylglycerol O-acyltransferase activity	7/4553	31/18639	0.225806451612903	0.92440291052337	0.662072425645878	1
GO:0070325	lipoprotein particle receptor binding	7/4553	31/18639	0.225806451612903	0.92440291052337	0.662072425645878	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	16/4553	70/18639	0.228571428571429	0.935722129835901	0.664938256053651	1
GO:0071949	FAD binding	9/4553	40/18639	0.225	0.921101471557215	0.670826067296199	1
GO:0008525	phosphatidylcholine transporter activity	4/4553	18/18639	0.222222222222222	0.90972984845157	0.67453428837807	1
GO:0015373	monoatomic anion:sodium symporter activity	4/4553	18/18639	0.222222222222222	0.90972984845157	0.67453428837807	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/4553	18/18639	0.222222222222222	0.90972984845157	0.67453428837807	1
GO:0035615	clathrin adaptor activity	4/4553	18/18639	0.222222222222222	0.90972984845157	0.67453428837807	1
GO:0005525	GTP binding	89/4553	378/18639	0.235449735449735	0.963880434668926	0.675786717689537	1
GO:0008266	poly(U) RNA binding	6/4553	27/18639	0.222222222222222	0.90972984845157	0.677048674716105	1
GO:0008320	protein transmembrane transporter activity	6/4553	27/18639	0.222222222222222	0.90972984845157	0.677048674716105	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/4553	27/18639	0.222222222222222	0.90972984845157	0.677048674716105	1
GO:0035255	ionotropic glutamate receptor binding	6/4553	27/18639	0.222222222222222	0.90972984845157	0.677048674716105	1
GO:0019001	guanyl nucleotide binding	94/4553	400/18639	0.235	0.962039314737536	0.687157584354178	1
GO:0032561	guanyl ribonucleotide binding	94/4553	400/18639	0.235	0.962039314737536	0.687157584354178	1
GO:0031681	G-protein beta-subunit binding	5/4553	23/18639	0.217391304347826	0.889953112615667	0.695228206533857	1
GO:0008378	galactosyltransferase activity	7/4553	32/18639	0.21875	0.895515319569515	0.696874114645203	1
GO:0004065	arylsulfatase activity	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:0015386	potassium:proton antiporter activity	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:0019992	diacylglycerol binding	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:0043176	amine binding	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:0044548	S100 protein binding	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:0070742	C2H2 zinc finger domain binding	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:1901612	cardiolipin binding	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:1990825	sequence-specific mRNA binding	3/4553	14/18639	0.214285714285714	0.877239496721157	0.702143324493282	1
GO:0042626	ATPase-coupled transmembrane transporter activity	22/4553	98/18639	0.224489795918367	0.919012806088831	0.712616758223849	1
GO:0045499	chemorepellent activity	6/4553	28/18639	0.214285714285714	0.877239496721157	0.713237260690245	1
GO:0050698	proteoglycan sulfotransferase activity	6/4553	28/18639	0.214285714285714	0.877239496721157	0.713237260690245	1
GO:0051393	alpha-actinin binding	6/4553	28/18639	0.214285714285714	0.877239496721157	0.713237260690245	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0008381	mechanosensitive monoatomic ion channel activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0016918	retinal binding	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0022821	solute:potassium antiporter activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0022840	leak channel activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0022842	narrow pore channel activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0042577	lipid phosphatase activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0070003	threonine-type peptidase activity	4/4553	19/18639	0.210526315789474	0.861849330112014	0.718069557696886	1
GO:0005548	phospholipid transporter activity	15/4553	68/18639	0.220588235294118	0.903040658389426	0.719241930027227	1
GO:0032934	sterol binding	15/4553	68/18639	0.220588235294118	0.903040658389426	0.719241930027227	1
GO:0005315	phosphate transmembrane transporter activity	5/4553	24/18639	0.208333333333333	0.852871732923347	0.732873016161771	1
GO:0005540	hyaluronic acid binding	5/4553	24/18639	0.208333333333333	0.852871732923347	0.732873016161771	1
GO:0015291	secondary active transmembrane transporter activity	66/4553	287/18639	0.229965156794425	0.941427752578803	0.735927710798491	1
GO:0015108	chloride transmembrane transporter activity	27/4553	121/18639	0.223140495867769	0.91348906270137	0.738339454092393	1
GO:0001094	TFIID-class transcription factor complex binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0004955	prostaglandin receptor activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0005337	nucleoside transmembrane transporter activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0005528	FK506 binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0015187	glycine transmembrane transporter activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0015203	polyamine transmembrane transporter activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0016427	tRNA (cytidine) methyltransferase activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0019911	structural constituent of myelin sheath	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0033204	ribonuclease P RNA binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0070097	delta-catenin binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0070739	protein-glutamic acid ligase activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0070740	tubulin-glutamic acid ligase activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0140940	histone H2A methyltransferase activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0141109	transporter activator activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:1905394	retromer complex binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:1990757	ubiquitin ligase activator activity	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:1990763	arrestin family protein binding	2/4553	10/18639	0.2	0.818756863606413	0.742901899824875	1
GO:1901681	sulfur compound binding	63/4553	275/18639	0.229090909090909	0.937848771040073	0.743545404372362	1
GO:0140359	ABC-type transporter activity	10/4553	47/18639	0.212765957446809	0.871017940006823	0.744246279734217	1
GO:0004181	metallocarboxypeptidase activity	6/4553	29/18639	0.206896551724138	0.846989858903186	0.746529342857474	1
GO:0035250	UDP-galactosyltransferase activity	6/4553	29/18639	0.206896551724138	0.846989858903186	0.746529342857474	1
GO:0099604	ligand-gated calcium channel activity	6/4553	29/18639	0.206896551724138	0.846989858903186	0.746529342857474	1
GO:0004467	long-chain fatty acid-CoA ligase activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0004953	icosanoid receptor activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0010181	FMN binding	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0016846	carbon-sulfur lyase activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0030553	cGMP binding	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0031005	filamin binding	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0034483	heparan sulfate sulfotransferase activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0045504	dynein heavy chain binding	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0048531	beta-1,3-galactosyltransferase activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0140161	monocarboxylate:sodium symporter activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0141050	histone H3K deacetylase activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0141051	histone H4K deacetylase activity	3/4553	15/18639	0.2	0.818756863606413	0.748187313356554	1
GO:0120013	lipid transfer activity	14/4553	65/18639	0.215384615384615	0.881738160806907	0.749853391841079	1
GO:0010851	cyclase regulator activity	4/4553	20/18639	0.2	0.818756863606413	0.757137464239301	1
GO:0016408	C-acyltransferase activity	4/4553	20/18639	0.2	0.818756863606413	0.757137464239301	1
GO:0030742	GTP-dependent protein binding	4/4553	20/18639	0.2	0.818756863606413	0.757137464239301	1
GO:0042288	MHC class I protein binding	4/4553	20/18639	0.2	0.818756863606413	0.757137464239301	1
GO:0005254	chloride channel activity	18/4553	83/18639	0.216867469879518	0.887808647284063	0.757801918697006	1
GO:0008175	tRNA methyltransferase activity	7/4553	34/18639	0.205882352941176	0.842837947830131	0.759137234379361	1
GO:0008376	acetylgalactosaminyltransferase activity	7/4553	34/18639	0.205882352941176	0.842837947830131	0.759137234379361	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	7/4553	34/18639	0.205882352941176	0.842837947830131	0.759137234379361	1
GO:0090482	vitamin transmembrane transporter activity	7/4553	34/18639	0.205882352941176	0.842837947830131	0.759137234379361	1
GO:0015370	solute:sodium symporter activity	17/4553	79/18639	0.215189873417722	0.880940929196774	0.765300070945207	1
GO:0047617	fatty acyl-CoA hydrolase activity	5/4553	25/18639	0.2	0.818756863606413	0.767009972618554	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/4553	48/18639	0.208333333333333	0.852871732923347	0.768868270770362	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/4553	57/18639	0.210526315789474	0.861849330112014	0.769176337881705	1
GO:0008509	monoatomic anion transmembrane transporter activity	33/4553	149/18639	0.221476510067114	0.906677063725223	0.769944246517259	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/4553	39/18639	0.205128205128205	0.839750629339911	0.770811434006939	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/4553	30/18639	0.2	0.818756863606413	0.776928344276993	1
GO:0008187	poly-pyrimidine tract binding	6/4553	30/18639	0.2	0.818756863606413	0.776928344276993	1
GO:0033612	receptor serine/threonine kinase binding	6/4553	30/18639	0.2	0.818756863606413	0.776928344276993	1
GO:0070566	adenylyltransferase activity	6/4553	30/18639	0.2	0.818756863606413	0.776928344276993	1
GO:0004623	phospholipase A2 activity	7/4553	35/18639	0.2	0.818756863606413	0.786568441839876	1
GO:0016229	steroid dehydrogenase activity	7/4553	35/18639	0.2	0.818756863606413	0.786568441839876	1
GO:0015293	symporter activity	32/4553	146/18639	0.219178082191781	0.897267795733056	0.78796904823411	1
GO:0000062	fatty-acyl-CoA binding	3/4553	16/18639	0.1875	0.767584559631012	0.788335453427782	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/4553	16/18639	0.1875	0.767584559631012	0.788335453427782	1
GO:0015378	sodium:chloride symporter activity	3/4553	16/18639	0.1875	0.767584559631012	0.788335453427782	1
GO:0015385	sodium:proton antiporter activity	3/4553	16/18639	0.1875	0.767584559631012	0.788335453427782	1
GO:0043023	ribosomal large subunit binding	3/4553	16/18639	0.1875	0.767584559631012	0.788335453427782	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0004954	prostanoid receptor activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0008526	phosphatidylinositol transfer activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0010854	adenylate cyclase regulator activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0016594	glycine binding	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0035252	UDP-xylosyltransferase activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0042285	xylosyltransferase activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0050998	nitric-oxide synthase binding	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/4553	11/18639	0.181818181818182	0.744324421460376	0.790887614123366	1
GO:0017022	myosin binding	16/4553	76/18639	0.210526315789474	0.861849330112014	0.791680013488677	1
GO:0001846	opsonin binding	4/4553	21/18639	0.19047619047619	0.779768441529917	0.791870197408883	1
GO:1904047	S-adenosyl-L-methionine binding	4/4553	21/18639	0.19047619047619	0.779768441529917	0.791870197408883	1
GO:0004857	enzyme inhibitor activity	95/4553	416/18639	0.228365384615385	0.934878630319823	0.793417684908056	1
GO:0004177	aminopeptidase activity	8/4553	40/18639	0.2	0.818756863606413	0.795807775684625	1
GO:0005227	calcium-activated cation channel activity	5/4553	26/18639	0.192307692307692	0.787266215006167	0.79771973213911	1
GO:0016289	acyl-CoA hydrolase activity	5/4553	26/18639	0.192307692307692	0.787266215006167	0.79771973213911	1
GO:0030507	spectrin binding	5/4553	26/18639	0.192307692307692	0.787266215006167	0.79771973213911	1
GO:0070006	metalloaminopeptidase activity	5/4553	26/18639	0.192307692307692	0.787266215006167	0.79771973213911	1
GO:0047499	calcium-independent phospholipase A2 activity	6/4553	31/18639	0.193548387096774	0.792345351877174	0.804493764748461	1
GO:0015103	inorganic anion transmembrane transporter activity	36/4553	165/18639	0.218181818181818	0.893189305752451	0.80811026665832	1
GO:0016209	antioxidant activity	18/4553	86/18639	0.209302325581395	0.856838578192758	0.80993714289791	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/4553	59/18639	0.203389830508475	0.832634098582793	0.810077043355687	1
GO:0004033	aldo-keto reductase (NADPH) activity	7/4553	36/18639	0.194444444444444	0.796013617395124	0.811585266191325	1
GO:0045505	dynein intermediate chain binding	7/4553	36/18639	0.194444444444444	0.796013617395124	0.811585266191325	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/4553	36/18639	0.194444444444444	0.796013617395124	0.811585266191325	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/4553	36/18639	0.194444444444444	0.796013617395124	0.811585266191325	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/4553	36/18639	0.194444444444444	0.796013617395124	0.811585266191325	1
GO:0015605	organophosphate ester transmembrane transporter activity	10/4553	50/18639	0.2	0.818756863606413	0.812962907067405	1
GO:0001530	lipopolysaccharide binding	8/4553	41/18639	0.195121951219512	0.798787184006257	0.818702365060605	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/4553	41/18639	0.195121951219512	0.798787184006257	0.818702365060605	1
GO:0016881	acid-amino acid ligase activity	4/4553	22/18639	0.181818181818182	0.744324421460376	0.822490956537504	1
GO:0061133	endopeptidase activator activity	4/4553	22/18639	0.181818181818182	0.744324421460376	0.822490956537504	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:0004659	prenyltransferase activity	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:0009881	photoreceptor activity	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:0016018	cyclosporin A binding	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:0045236	CXCR chemokine receptor binding	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:0051787	misfolded protein binding	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:1901567	fatty acid derivative binding	3/4553	17/18639	0.176470588235294	0.722432526711541	0.823008693137352	1
GO:0004364	glutathione transferase activity	5/4553	27/18639	0.185185185185185	0.758108207042975	0.82514497246252	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/4553	32/18639	0.1875	0.767584559631012	0.829329068618443	1
GO:0008194	UDP-glycosyltransferase activity	31/4553	145/18639	0.213793103448276	0.875222854199959	0.829800508340138	1
GO:0003720	telomerase activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0003995	acyl-CoA dehydrogenase activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0004526	ribonuclease P activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0004859	phospholipase inhibitor activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0005527	macrolide binding	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0010853	cyclase activator activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0015132	prostaglandin transmembrane transporter activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0015166	polyol transmembrane transporter activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0015368	calcium:monoatomic cation antiporter activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0016208	AMP binding	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0017166	vinculin binding	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0042301	phosphate ion binding	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/4553	12/18639	0.166666666666667	0.682297386338678	0.830776189933859	1
GO:0005010	insulin-like growth factor receptor activity	10/4553	51/18639	0.196078431372549	0.802702807457268	0.83249436275014	1
GO:0008307	structural constituent of muscle	8/4553	42/18639	0.19047619047619	0.779768441529917	0.839563628201688	1
GO:0016859	cis-trans isomerase activity	8/4553	42/18639	0.19047619047619	0.779768441529917	0.839563628201688	1
GO:0031492	nucleosomal DNA binding	8/4553	42/18639	0.19047619047619	0.779768441529917	0.839563628201688	1
GO:0042056	chemoattractant activity	8/4553	42/18639	0.19047619047619	0.779768441529917	0.839563628201688	1
GO:0016782	transferase activity, transferring sulphur-containing groups	14/4553	70/18639	0.2	0.818756863606413	0.842306656400821	1
GO:0000295	adenine nucleotide transmembrane transporter activity	4/4553	23/18639	0.173913043478261	0.711962490092533	0.849283114433008	1
GO:0005212	structural constituent of eye lens	4/4553	23/18639	0.173913043478261	0.711962490092533	0.849283114433008	1
GO:0005283	amino acid:sodium symporter activity	4/4553	23/18639	0.173913043478261	0.711962490092533	0.849283114433008	1
GO:0017134	fibroblast growth factor binding	4/4553	23/18639	0.173913043478261	0.711962490092533	0.849283114433008	1
GO:0046625	sphingolipid binding	5/4553	28/18639	0.178571428571429	0.731032913934298	0.849472735891276	1
GO:0051119	sugar transmembrane transporter activity	5/4553	28/18639	0.178571428571429	0.731032913934298	0.849472735891276	1
GO:0008235	metalloexopeptidase activity	13/4553	66/18639	0.196969696969697	0.806351456582074	0.851417667179696	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/4553	18/18639	0.166666666666667	0.682297386338678	0.852703574089209	1
GO:1901611	phosphatidylglycerol binding	3/4553	18/18639	0.166666666666667	0.682297386338678	0.852703574089209	1
GO:1990381	ubiquitin-specific protease binding	3/4553	18/18639	0.166666666666667	0.682297386338678	0.852703574089209	1
GO:0005319	lipid transporter activity	38/4553	178/18639	0.213483146067416	0.873953955534936	0.85318814052057	1
GO:0004601	peroxidase activity	11/4553	57/18639	0.192982456140351	0.79002855260268	0.855766110887634	1
GO:0005253	monoatomic anion channel activity	21/4553	103/18639	0.203883495145631	0.834655055132752	0.858905200820575	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/4553	13/18639	0.153846153846154	0.629812972004933	0.863659341552975	1
GO:0004465	lipoprotein lipase activity	2/4553	13/18639	0.153846153846154	0.629812972004933	0.863659341552975	1
GO:0070700	BMP receptor binding	2/4553	13/18639	0.153846153846154	0.629812972004933	0.863659341552975	1
GO:0140333	glycerophospholipid flippase activity	2/4553	13/18639	0.153846153846154	0.629812972004933	0.863659341552975	1
GO:1901338	catecholamine binding	2/4553	13/18639	0.153846153846154	0.629812972004933	0.863659341552975	1
GO:0008146	sulfotransferase activity	10/4553	53/18639	0.188679245283019	0.772412135477748	0.866788867780715	1
GO:0038064	collagen receptor activity	10/4553	53/18639	0.188679245283019	0.772412135477748	0.866788867780715	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	25/4553	122/18639	0.204918032786885	0.838890229104932	0.869974948658909	1
GO:0042379	chemokine receptor binding	14/4553	72/18639	0.194444444444444	0.796013617395124	0.871005227283132	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/4553	34/18639	0.176470588235294	0.722432526711541	0.871377747861409	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/4553	24/18639	0.166666666666667	0.682297386338678	0.872565134087256	1
GO:0140612	DNA damage sensor activity	4/4553	24/18639	0.166666666666667	0.682297386338678	0.872565134087256	1
GO:0005539	glycosaminoglycan binding	52/4553	242/18639	0.214876033057851	0.879656134453171	0.875157189628776	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/4553	19/18639	0.157894736842105	0.646386997584011	0.877947452162769	1
GO:0031420	alkali metal ion binding	3/4553	19/18639	0.157894736842105	0.646386997584011	0.877947452162769	1
GO:0034987	immunoglobulin receptor binding	3/4553	19/18639	0.157894736842105	0.646386997584011	0.877947452162769	1
GO:0042834	peptidoglycan binding	3/4553	19/18639	0.157894736842105	0.646386997584011	0.877947452162769	1
GO:0046624	sphingolipid transporter activity	3/4553	19/18639	0.157894736842105	0.646386997584011	0.877947452162769	1
GO:0008201	heparin binding	36/4553	172/18639	0.209302325581395	0.856838578192758	0.87851518062196	1
GO:0140223	general transcription initiation factor activity	13/4553	68/18639	0.191176470588235	0.782635237270836	0.879579062789918	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	27/4553	132/18639	0.204545454545455	0.837364974142923	0.880022748624718	1
GO:0070888	E-box binding	11/4553	59/18639	0.186440677966102	0.763247923700894	0.885057702479202	1
GO:0015144	carbohydrate transmembrane transporter activity	7/4553	40/18639	0.175	0.716412255655612	0.889476158395549	1
GO:0050997	quaternary ammonium group binding	7/4553	40/18639	0.175	0.716412255655612	0.889476158395549	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/4553	30/18639	0.166666666666667	0.682297386338678	0.889717462472583	1
GO:0022839	monoatomic ion-gated channel activity	5/4553	30/18639	0.166666666666667	0.682297386338678	0.889717462472583	1
GO:0031210	phosphatidylcholine binding	5/4553	30/18639	0.166666666666667	0.682297386338678	0.889717462472583	1
GO:0005347	ATP transmembrane transporter activity	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:0008195	phosphatidate phosphatase activity	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:0008559	ABC-type xenobiotic transporter activity	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:1901474	azole transmembrane transporter activity	2/4553	14/18639	0.142857142857143	0.584826331147438	0.89057867772959	1
GO:0001848	complement binding	4/4553	25/18639	0.16	0.655005490885131	0.892670879128913	1
GO:0005251	delayed rectifier potassium channel activity	4/4553	25/18639	0.16	0.655005490885131	0.892670879128913	1
GO:0015271	outward rectifier potassium channel activity	4/4553	25/18639	0.16	0.655005490885131	0.892670879128913	1
GO:0015662	P-type ion transporter activity	4/4553	25/18639	0.16	0.655005490885131	0.892670879128913	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/4553	25/18639	0.16	0.655005490885131	0.892670879128913	1
GO:0140358	P-type transmembrane transporter activity	4/4553	25/18639	0.16	0.655005490885131	0.892670879128913	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/4553	88/18639	0.193181818181818	0.790844697801649	0.895493997982677	1
GO:0015171	amino acid transmembrane transporter activity	20/4553	102/18639	0.196078431372549	0.802702807457268	0.897005006724601	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	11/4553	60/18639	0.183333333333333	0.750527124972545	0.89777530910091	1
GO:0000339	RNA cap binding	3/4553	20/18639	0.15	0.61406764770481	0.899266861796322	1
GO:0031418	L-ascorbic acid binding	3/4553	20/18639	0.15	0.61406764770481	0.899266861796322	1
GO:0140664	ATP-dependent DNA damage sensor activity	3/4553	20/18639	0.15	0.61406764770481	0.899266861796322	1
GO:0019843	rRNA binding	12/4553	65/18639	0.184615384615385	0.75577556640592	0.900490890012142	1
GO:0003743	translation initiation factor activity	9/4553	51/18639	0.176470588235294	0.722432526711541	0.905800260890362	1
GO:0005021	vascular endothelial growth factor receptor activity	9/4553	51/18639	0.176470588235294	0.722432526711541	0.905800260890362	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/4553	31/18639	0.161290322580645	0.660287793230978	0.906106635111837	1
GO:0005452	solute:inorganic anion antiporter activity	5/4553	31/18639	0.161290322580645	0.660287793230978	0.906106635111837	1
GO:0008198	ferrous iron binding	4/4553	26/18639	0.153846153846154	0.629812972004933	0.90993472403615	1
GO:0015145	monosaccharide transmembrane transporter activity	4/4553	26/18639	0.153846153846154	0.629812972004933	0.90993472403615	1
GO:0015216	purine nucleotide transmembrane transporter activity	4/4553	26/18639	0.153846153846154	0.629812972004933	0.90993472403615	1
GO:0120014	phospholipid transfer activity	4/4553	26/18639	0.153846153846154	0.629812972004933	0.90993472403615	1
GO:0022804	active transmembrane transporter activity	100/4553	457/18639	0.218818380743982	0.895795255586886	0.910696384457445	1
GO:0000774	adenyl-nucleotide exchange factor activity	2/4553	15/18639	0.133333333333333	0.545837909070942	0.912485041479288	1
GO:0004129	cytochrome-c oxidase activity	2/4553	15/18639	0.133333333333333	0.545837909070942	0.912485041479288	1
GO:0008020	G protein-coupled photoreceptor activity	2/4553	15/18639	0.133333333333333	0.545837909070942	0.912485041479288	1
GO:0008242	omega peptidase activity	2/4553	15/18639	0.133333333333333	0.545837909070942	0.912485041479288	1
GO:0015116	sulfate transmembrane transporter activity	2/4553	15/18639	0.133333333333333	0.545837909070942	0.912485041479288	1
GO:0033130	acetylcholine receptor binding	2/4553	15/18639	0.133333333333333	0.545837909070942	0.912485041479288	1
GO:0001664	G protein-coupled receptor binding	63/4553	297/18639	0.212121212121212	0.868378491703772	0.916038357841534	1
GO:0099095	ligand-gated monoatomic anion channel activity	8/4553	47/18639	0.170212765957447	0.696814352005458	0.916845434124752	1
GO:0009975	cyclase activity	3/4553	21/18639	0.142857142857143	0.584826331147438	0.917166305860895	1
GO:0015125	bile acid transmembrane transporter activity	3/4553	21/18639	0.142857142857143	0.584826331147438	0.917166305860895	1
GO:0036122	BMP binding	3/4553	21/18639	0.142857142857143	0.584826331147438	0.917166305860895	1
GO:0015106	bicarbonate transmembrane transporter activity	5/4553	32/18639	0.15625	0.63965379969251	0.920324702980984	1
GO:0031369	translation initiation factor binding	5/4553	32/18639	0.15625	0.63965379969251	0.920324702980984	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/4553	32/18639	0.15625	0.63965379969251	0.920324702980984	1
GO:0016405	CoA-ligase activity	4/4553	27/18639	0.148148148148148	0.60648656563438	0.924680767788085	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/4553	53/18639	0.169811320754717	0.695170921929974	0.927743365109059	1
GO:0005245	voltage-gated calcium channel activity	7/4553	43/18639	0.162790697674419	0.666430005261034	0.928312121399579	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/4553	16/18639	0.125	0.511723039754008	0.930220696915217	1
GO:0019841	retinol binding	2/4553	16/18639	0.125	0.511723039754008	0.930220696915217	1
GO:0055102	lipase inhibitor activity	2/4553	16/18639	0.125	0.511723039754008	0.930220696915217	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/4553	16/18639	0.125	0.511723039754008	0.930220696915217	1
GO:0015399	primary active transmembrane transporter activity	33/4553	166/18639	0.198795180722892	0.813824593343724	0.930606563495526	1
GO:0004521	RNA endonuclease activity	13/4553	73/18639	0.178082191780822	0.729030084033108	0.931511738503035	1
GO:0005243	gap junction channel activity	3/4553	22/18639	0.136363636363636	0.558243316095282	0.932115045227747	1
GO:0009055	electron transfer activity	22/4553	116/18639	0.189655172413793	0.776407370661254	0.934164926152485	1
GO:0017069	snRNA binding	9/4553	54/18639	0.166666666666667	0.682297386338678	0.93695377134477	1
GO:0036002	pre-mRNA binding	10/4553	59/18639	0.169491525423729	0.693861748818994	0.937070278096928	1
GO:0005004	GPI-linked ephrin receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0005008	hepatocyte growth factor receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0005009	insulin receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0005011	macrophage colony-stimulating factor receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0005020	stem cell factor receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0008288	boss receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0036332	placental growth factor receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0038062	protein tyrosine kinase collagen receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0060175	brain-derived neurotrophic factor receptor activity	8/4553	49/18639	0.163265306122449	0.668372949882786	0.937307878789672	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	36/4553	181/18639	0.198895027624309	0.814233345022953	0.937761328857891	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/4553	44/18639	0.159090909090909	0.651283868777829	0.938294038465067	1
GO:0005200	structural constituent of cytoskeleton	21/4553	112/18639	0.1875	0.767584559631012	0.938379368860225	1
GO:0000182	rDNA binding	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0003796	lysozyme activity	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0008519	ammonium channel activity	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0019531	oxalate transmembrane transporter activity	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0032052	bile acid binding	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0043121	neurotrophin binding	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0051378	serotonin binding	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/4553	10/18639	0.1	0.409378431803207	0.939282803090824	1
GO:0005201	extracellular matrix structural constituent	33/4553	168/18639	0.196428571428571	0.804136205327727	0.94107587181162	1
GO:0180051	translation factor activity	15/4553	84/18639	0.178571428571429	0.731032913934298	0.941478741601308	1
GO:0005496	steroid binding	20/4553	108/18639	0.185185185185185	0.758108207042975	0.942601784201898	1
GO:0008569	minus-end-directed microtubule motor activity	2/4553	17/18639	0.117647058823529	0.481621684474361	0.944515630752266	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/4553	17/18639	0.117647058823529	0.481621684474361	0.944515630752266	1
GO:0016849	phosphorus-oxygen lyase activity	3/4553	23/18639	0.130434782608696	0.5339718675694	0.944539834846958	1
GO:0099186	structural constituent of postsynapse	3/4553	23/18639	0.130434782608696	0.5339718675694	0.944539834846958	1
GO:0005006	epidermal growth factor receptor activity	8/4553	50/18639	0.16	0.655005490885131	0.945773393621144	1
GO:0005007	fibroblast growth factor receptor activity	8/4553	50/18639	0.16	0.655005490885131	0.945773393621144	1
GO:0005017	platelet-derived growth factor receptor activity	8/4553	50/18639	0.16	0.655005490885131	0.945773393621144	1
GO:0005019	platelet-derived growth factor beta-receptor activity	8/4553	50/18639	0.16	0.655005490885131	0.945773393621144	1
GO:0048020	CCR chemokine receptor binding	8/4553	50/18639	0.16	0.655005490885131	0.945773393621144	1
GO:0005416	amino acid:monoatomic cation symporter activity	4/4553	29/18639	0.137931034482759	0.564659905935457	0.947822825957165	1
GO:0015036	disulfide oxidoreductase activity	6/4553	40/18639	0.15	0.61406764770481	0.949077527596033	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	10/4553	61/18639	0.163934426229508	0.671112183283945	0.951914314272605	1
GO:0140299	molecular sensor activity	12/4553	71/18639	0.169014084507042	0.691907208681476	0.952000193572342	1
GO:0005030	neurotrophin receptor activity	8/4553	51/18639	0.156862745098039	0.642162245965814	0.953210255524545	1
GO:0003953	NAD+ nucleosidase activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0005536	D-glucose binding	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0008046	axon guidance receptor activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0008172	S-methyltransferase activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0008503	benzodiazepine receptor activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0015217	ADP transmembrane transporter activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0031731	CCR6 chemokine receptor binding	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0070697	activin receptor binding	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/4553	11/18639	0.0909090909090909	0.372162210730188	0.95412232198757	1
GO:0015149	hexose transmembrane transporter activity	3/4553	24/18639	0.125	0.511723039754008	0.954821934955487	1
GO:0055056	D-glucose transmembrane transporter activity	3/4553	24/18639	0.125	0.511723039754008	0.954821934955487	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/4553	24/18639	0.125	0.511723039754008	0.954821934955487	1
GO:0003746	translation elongation factor activity	2/4553	18/18639	0.111111111111111	0.454864924225785	0.955992137835148	1
GO:0017128	phospholipid scramblase activity	2/4553	18/18639	0.111111111111111	0.454864924225785	0.955992137835148	1
GO:0070628	proteasome binding	2/4553	18/18639	0.111111111111111	0.454864924225785	0.955992137835148	1
GO:0098641	cadherin binding involved in cell-cell adhesion	2/4553	18/18639	0.111111111111111	0.454864924225785	0.955992137835148	1
GO:0015215	nucleotide transmembrane transporter activity	4/4553	30/18639	0.133333333333333	0.545837909070942	0.9567621126471	1
GO:0048019	receptor antagonist activity	4/4553	30/18639	0.133333333333333	0.545837909070942	0.9567621126471	1
GO:0098918	structural constituent of synapse	4/4553	30/18639	0.133333333333333	0.545837909070942	0.9567621126471	1
GO:0042287	MHC protein binding	6/4553	41/18639	0.146341463414634	0.599090388004693	0.956797006584966	1
GO:0016829	lyase activity	39/4553	200/18639	0.195	0.798287942016253	0.959412307159501	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/4553	36/18639	0.138888888888889	0.568581155282232	0.959907554948121	1
GO:0005262	calcium channel activity	24/4553	131/18639	0.183206106870229	0.75000628727305	0.962085053914476	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/4553	68/18639	0.161764705882353	0.662229816152246	0.963150789244519	1
GO:0008135	translation factor activity, RNA binding	14/4553	83/18639	0.168674698795181	0.690517836776493	0.963169350396817	1
GO:0005537	D-mannose binding	3/4553	25/18639	0.12	0.491254118163848	0.963297078931837	1
GO:0015645	fatty acid ligase activity	3/4553	25/18639	0.12	0.491254118163848	0.963297078931837	1
GO:0120515	fatty acid-CoA ligase activity	3/4553	25/18639	0.12	0.491254118163848	0.963297078931837	1
GO:0016878	acid-thiol ligase activity	4/4553	31/18639	0.129032258064516	0.528230234584783	0.96426662783751	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	9/4553	58/18639	0.155172413793103	0.63524239417739	0.964303079927094	1
GO:0046943	carboxylic acid transmembrane transporter activity	36/4553	188/18639	0.191489361702128	0.78391614600614	0.965151991852284	1
GO:0003756	protein disulfide isomerase activity	2/4553	19/18639	0.105263157894737	0.430924665056007	0.96517386556131	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/4553	19/18639	0.105263157894737	0.430924665056007	0.96517386556131	1
GO:0030506	ankyrin binding	2/4553	19/18639	0.105263157894737	0.430924665056007	0.96517386556131	1
GO:0000340	RNA 7-methylguanosine cap binding	1/4553	12/18639	0.0833333333333333	0.341148693169339	0.965335606719726	1
GO:0004032	aldose reductase (NADPH) activity	1/4553	12/18639	0.0833333333333333	0.341148693169339	0.965335606719726	1
GO:0008179	adenylate cyclase binding	1/4553	12/18639	0.0833333333333333	0.341148693169339	0.965335606719726	1
GO:0015269	calcium-activated potassium channel activity	1/4553	12/18639	0.0833333333333333	0.341148693169339	0.965335606719726	1
GO:1990817	poly(A) RNA polymerase activity	1/4553	12/18639	0.0833333333333333	0.341148693169339	0.965335606719726	1
GO:0005003	ephrin receptor activity	8/4553	53/18639	0.150943396226415	0.617929708382199	0.965407745812453	1
GO:0005005	transmembrane-ephrin receptor activity	8/4553	53/18639	0.150943396226415	0.617929708382199	0.965407745812453	1
GO:0005544	calcium-dependent phospholipid binding	8/4553	53/18639	0.150943396226415	0.617929708382199	0.965407745812453	1
GO:0016860	intramolecular oxidoreductase activity	8/4553	53/18639	0.150943396226415	0.617929708382199	0.965407745812453	1
GO:0022853	active monoatomic ion transmembrane transporter activity	21/4553	118/18639	0.177966101694915	0.728554836259944	0.966905865585897	1
GO:0048029	monosaccharide binding	12/4553	74/18639	0.162162162162162	0.663856916437633	0.967571273588794	1
GO:0005342	organic acid transmembrane transporter activity	36/4553	189/18639	0.19047619047619	0.779768441529917	0.968053935492169	1
GO:0004867	serine-type endopeptidase inhibitor activity	16/4553	95/18639	0.168421052631579	0.689479464089611	0.971607529575134	1
GO:0044183	protein folding chaperone	12/4553	75/18639	0.16	0.655005490885131	0.971652573525006	1
GO:0030955	potassium ion binding	1/4553	13/18639	0.0769230769230769	0.314906486002467	0.973808628816955	1
GO:0031432	titin binding	1/4553	13/18639	0.0769230769230769	0.314906486002467	0.973808628816955	1
GO:0008395	steroid hydroxylase activity	3/4553	27/18639	0.111111111111111	0.454864924225785	0.975954463380152	1
GO:0015252	proton channel activity	3/4553	27/18639	0.111111111111111	0.454864924225785	0.975954463380152	1
GO:0005248	voltage-gated sodium channel activity	2/4553	21/18639	0.0952380952380952	0.389884220764959	0.978321135465826	1
GO:0051428	peptide hormone receptor binding	2/4553	21/18639	0.0952380952380952	0.389884220764959	0.978321135465826	1
GO:0061134	peptidase regulator activity	43/4553	226/18639	0.190265486725664	0.77890586582026	0.978445816602334	1
GO:0008191	metalloendopeptidase inhibitor activity	1/4553	14/18639	0.0714285714285714	0.292413165573719	0.980210932746752	1
GO:0008331	high voltage-gated calcium channel activity	1/4553	14/18639	0.0714285714285714	0.292413165573719	0.980210932746752	1
GO:0032036	myosin heavy chain binding	1/4553	14/18639	0.0714285714285714	0.292413165573719	0.980210932746752	1
GO:0061783	peptidoglycan muralytic activity	1/4553	14/18639	0.0714285714285714	0.292413165573719	0.980210932746752	1
GO:0015078	proton transmembrane transporter activity	34/4553	185/18639	0.183783783783784	0.75237117196265	0.980383460432888	1
GO:0015085	calcium ion transmembrane transporter activity	26/4553	147/18639	0.17687074829932	0.724070695706352	0.980515298032939	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/4553	52/18639	0.134615384615385	0.551086350504317	0.982967302858875	1
GO:0004222	metalloendopeptidase activity	18/4553	110/18639	0.163636363636364	0.669891979314338	0.984759091749366	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/4553	15/18639	0.0666666666666667	0.272918954535471	0.985048496408714	1
GO:0015250	water channel activity	1/4553	15/18639	0.0666666666666667	0.272918954535471	0.985048496408714	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/4553	15/18639	0.0666666666666667	0.272918954535471	0.985048496408714	1
GO:0031386	protein tag activity	1/4553	15/18639	0.0666666666666667	0.272918954535471	0.985048496408714	1
GO:0141047	molecular tag activity	1/4553	15/18639	0.0666666666666667	0.272918954535471	0.985048496408714	1
GO:0008237	metallopeptidase activity	33/4553	184/18639	0.179347826086957	0.734211317907925	0.986369021543257	1
GO:0016917	GABA receptor activity	2/4553	23/18639	0.0869565217391304	0.355981245046267	0.986599069217508	1
GO:0008142	oxysterol binding	1/4553	16/18639	0.0625	0.255861519877004	0.988703683041614	1
GO:0017070	U6 snRNA binding	1/4553	16/18639	0.0625	0.255861519877004	0.988703683041614	1
GO:0022829	wide pore channel activity	4/4553	37/18639	0.108108108108108	0.442571277625088	0.989162502076502	1
GO:0016836	hydro-lyase activity	8/4553	61/18639	0.131147540983607	0.536889746627156	0.99049339736971	1
GO:0140101	catalytic activity, acting on a tRNA	23/4553	139/18639	0.165467625899281	0.677388772048471	0.990733128265425	1
GO:0030547	signaling receptor inhibitor activity	5/4553	44/18639	0.113636363636364	0.465202763412735	0.990975251858261	1
GO:0015081	sodium ion transmembrane transporter activity	28/4553	164/18639	0.170731707317073	0.698938786005475	0.991150654663819	1
GO:0016500	protein-hormone receptor activity	9/4553	67/18639	0.134328358208955	0.549911326302815	0.991193690406141	1
GO:0030414	peptidase inhibitor activity	29/4553	169/18639	0.171597633136095	0.702483699543964	0.991270195400828	1
GO:0008514	organic anion transmembrane transporter activity	50/4553	269/18639	0.185873605947955	0.760926453165812	0.991271847290491	1
GO:0017171	serine hydrolase activity	35/4553	198/18639	0.176767676767677	0.723648743086477	0.991275096467006	1
GO:0030548	acetylcholine receptor regulator activity	1/4553	17/18639	0.0588235294117647	0.24081084223718	0.991465436309698	1
GO:0045125	bioactive lipid receptor activity	1/4553	17/18639	0.0588235294117647	0.24081084223718	0.991465436309698	1
GO:0070492	oligosaccharide binding	1/4553	17/18639	0.0588235294117647	0.24081084223718	0.991465436309698	1
GO:0042562	hormone binding	14/4553	94/18639	0.148936170212766	0.609712558004776	0.991521230086634	1
GO:0042910	xenobiotic transmembrane transporter activity	3/4553	32/18639	0.09375	0.383792279815506	0.9919455923079	1
GO:0016835	carbon-oxygen lyase activity	11/4553	79/18639	0.139240506329114	0.570020601244971	0.99260782044916	1
GO:0004175	endopeptidase activity	79/4553	405/18639	0.195061728395062	0.798540644751934	0.992648589271734	1
GO:0051082	unfolded protein binding	19/4553	121/18639	0.15702479338843	0.642825636715779	0.992835902030014	1
GO:0004866	endopeptidase inhibitor activity	27/4553	161/18639	0.167701863354037	0.686535258303514	0.992851393086845	1
GO:0004497	monooxygenase activity	16/4553	106/18639	0.150943396226415	0.617929708382199	0.993210764910873	1
GO:0005372	water transmembrane transporter activity	1/4553	18/18639	0.0555555555555556	0.227432462112893	0.993552100925848	1
GO:0015280	ligand-gated sodium channel activity	1/4553	18/18639	0.0555555555555556	0.227432462112893	0.993552100925848	1
GO:0022851	GABA-gated chloride ion channel activity	1/4553	18/18639	0.0555555555555556	0.227432462112893	0.993552100925848	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/4553	18/18639	0.0555555555555556	0.227432462112893	0.993552100925848	1
GO:0099602	neurotransmitter receptor regulator activity	1/4553	18/18639	0.0555555555555556	0.227432462112893	0.993552100925848	1
GO:0042923	neuropeptide binding	3/4553	33/18639	0.0909090909090909	0.372162210730188	0.99356241146752	1
GO:0000049	tRNA binding	11/4553	80/18639	0.1375	0.562895343729409	0.993675444689747	1
GO:0015020	glucuronosyltransferase activity	3/4553	34/18639	0.0882352941176471	0.361216263355771	0.99486264818192	1
GO:0015035	protein-disulfide reductase activity	3/4553	34/18639	0.0882352941176471	0.361216263355771	0.99486264818192	1
GO:0017046	peptide hormone binding	6/4553	53/18639	0.113207547169811	0.463447281286649	0.994943499947228	1
GO:0005104	fibroblast growth factor receptor binding	2/4553	27/18639	0.0740740740740741	0.30324328281719	0.99496595203976	1
GO:0061135	endopeptidase regulator activity	31/4553	184/18639	0.168478260869565	0.689713662277142	0.995092328319847	1
GO:0004890	GABA-A receptor activity	1/4553	19/18639	0.0526315789473684	0.215462332528004	0.995128669557211	1
GO:0008236	serine-type peptidase activity	33/4553	194/18639	0.170103092783505	0.696365373685867	0.995203861074855	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/4553	41/18639	0.0975609756097561	0.399393592003128	0.995295306351919	1
GO:0005242	inward rectifier potassium channel activity	2/4553	28/18639	0.0714285714285714	0.292413165573719	0.996070783257183	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/4553	20/18639	0.05	0.204689215901603	0.996319817113925	1
GO:0015464	acetylcholine receptor activity	1/4553	20/18639	0.05	0.204689215901603	0.996319817113925	1
GO:0008083	growth factor activity	26/4553	162/18639	0.160493827160494	0.657027112770579	0.996461965871581	1
GO:0046906	tetrapyrrole binding	24/4553	152/18639	0.157894736842105	0.646386997584011	0.996498250194159	1
GO:0005125	cytokine activity	40/4553	234/18639	0.170940170940171	0.699792191116593	0.997450302056974	1
GO:0003954	NADH dehydrogenase activity	4/4553	44/18639	0.0909090909090909	0.372162210730188	0.997525561646932	1
GO:0022832	voltage-gated channel activity	28/4553	175/18639	0.16	0.655005490885131	0.997527437939474	1
GO:0020037	heme binding	21/4553	142/18639	0.147887323943662	0.605418807596292	0.998275188756977	1
GO:0005244	voltage-gated monoatomic ion channel activity	27/4553	173/18639	0.15606936416185	0.638914315531016	0.998303748234028	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/4553	46/18639	0.0869565217391304	0.355981245046267	0.998398947598511	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/4553	23/18639	0.0434782608695652	0.177990622523133	0.998413319325788	1
GO:0046873	metal ion transmembrane transporter activity	84/4553	450/18639	0.186666666666667	0.764173072699319	0.998709129122412	1
GO:0071855	neuropeptide receptor binding	3/4553	40/18639	0.075	0.307033823852405	0.998710339639945	1
GO:0140662	ATP-dependent protein folding chaperone	3/4553	40/18639	0.075	0.307033823852405	0.998710339639945	1
GO:0015079	potassium ion transmembrane transporter activity	24/4553	160/18639	0.15	0.61406764770481	0.998753893098435	1
GO:0004812	aminoacyl-tRNA ligase activity	3/4553	41/18639	0.0731707317073171	0.299545194002346	0.998979947531105	1
GO:0008227	G protein-coupled amine receptor activity	3/4553	41/18639	0.0731707317073171	0.299545194002346	0.998979947531105	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/4553	41/18639	0.0731707317073171	0.299545194002346	0.998979947531105	1
GO:0016874	ligase activity	25/4553	167/18639	0.149700598802395	0.612841963777255	0.999021860587355	1
GO:0019825	oxygen binding	2/4553	34/18639	0.0588235294117647	0.24081084223718	0.999129183824567	1
GO:0005249	voltage-gated potassium channel activity	12/4553	98/18639	0.122448979591837	0.50127971241209	0.999166577632707	1
GO:0005272	sodium channel activity	4/4553	51/18639	0.0784313725490196	0.321081122982907	0.999472254252144	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/4553	36/18639	0.0555555555555556	0.227432462112893	0.999476395101127	1
GO:0005267	potassium channel activity	16/4553	124/18639	0.129032258064516	0.528230234584783	0.999532241536397	1
GO:0030280	structural constituent of skin epidermis	2/4553	37/18639	0.0540540540540541	0.221285638812544	0.999594400849351	1
GO:0022843	voltage-gated monoatomic cation channel activity	19/4553	143/18639	0.132867132867133	0.543929384913352	0.999682003008262	1
GO:0005179	hormone activity	17/4553	132/18639	0.128787878787879	0.527229798534433	0.999682651620763	1
GO:0004252	serine-type endopeptidase activity	25/4553	176/18639	0.142045454545455	0.581503454265919	0.999714420869357	1
GO:0008188	neuropeptide receptor activity	3/4553	48/18639	0.0625	0.255861519877004	0.99980773494074	1
GO:0005184	neuropeptide hormone activity	1/4553	31/18639	0.032258064516129	0.132057558646196	0.999831805869986	1
GO:0003735	structural constituent of ribosome	24/4553	175/18639	0.137142857142857	0.561433277901541	0.999846654344728	1
GO:0005506	iron ion binding	20/4553	154/18639	0.12987012987013	0.531660301043125	0.999863736924844	1
GO:0030515	snoRNA binding	1/4553	32/18639	0.03125	0.127930759938502	0.999872959560547	1
GO:0160041	neuropeptide activity	1/4553	32/18639	0.03125	0.127930759938502	0.999872959560547	1
GO:0003823	antigen binding	23/4553	174/18639	0.132183908045977	0.541132409854813	0.999920570980921	1
GO:0008528	G protein-coupled peptide receptor activity	13/4553	122/18639	0.10655737704918	0.436222919134564	0.999965670606952	1
GO:0003730	mRNA 3'-UTR binding	38/4553	262/18639	0.145038167938931	0.593754977424498	0.999974342111253	1
GO:0001653	peptide receptor activity	13/4553	128/18639	0.1015625	0.415774969800132	0.999988662486348	1
GO:0099094	ligand-gated monoatomic cation channel activity	14/4553	136/18639	0.102941176470588	0.421418973915066	0.99999201075663	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/4553	73/18639	0.0410958904109589	0.168237711699948	0.999999619067365	1
GO:0005261	monoatomic cation channel activity	47/4553	341/18639	0.13782991202346	0.564245932397382	0.999999660747751	1
GO:0015276	ligand-gated monoatomic ion channel activity	19/4553	186/18639	0.102150537634409	0.418182269046286	0.999999779976882	1
GO:0022834	ligand-gated channel activity	19/4553	188/18639	0.101063829787234	0.413733521503241	0.99999984764778	1
GO:0005216	monoatomic ion channel activity	66/4553	448/18639	0.147321428571429	0.603102153995796	0.999999872470097	1
GO:0022836	gated channel activity	41/4553	318/18639	0.128930817610063	0.527814959243128	0.999999915113972	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/4553	63/18639	0.0158730158730159	0.0649807034608264	0.999999978998381	1
GO:0022835	transmitter-gated channel activity	1/4553	63/18639	0.0158730158730159	0.0649807034608264	0.999999978998381	1
GO:0030594	neurotransmitter receptor activity	4/4553	97/18639	0.0412371134020619	0.168815848166271	0.999999991784111	1
GO:0098960	postsynaptic neurotransmitter receptor activity	1/4553	69/18639	0.0144927536231884	0.0593302075077111	0.999999996114282	1
GO:0030527	structural constituent of chromatin	1/4553	98/18639	0.0102040816326531	0.0417733093676741	0.999999999998894	1
GO:0005549	odorant binding	1/4553	111/18639	0.00900900900900901	0.0368809398020907	0.999999999999972	1
GO:0004984	olfactory receptor activity	1/4553	419/18639	0.00238663484486874	0.00977036830079252	1	1
GO:0030371	translation repressor activity	13/4553	329/18639	0.0395136778115502	0.161760474572696	1	1
GO:0045182	translation regulator activity	21/4553	356/18639	0.0589887640449438	0.241487277187285	1	1
GO:1903231	mRNA base-pairing translational repressor activity	1/4553	298/18639	0.00335570469798658	0.013737531268564	1	1