ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0042605	peptide antigen binding	16/1066	45/18639	0.355555555555556	6.21688555347092	1.57211893400393e-09	1.68531149725221e-06
GO:0023026	MHC class II protein complex binding	12/1066	27/18639	0.444444444444444	7.77110694183865	8.99435861430125e-09	3.60855077906792e-06
GO:0019955	cytokine binding	28/1066	144/18639	0.194444444444444	3.39985928705441	1.0098556284705e-08	3.60855077906792e-06
GO:0023023	MHC protein complex binding	13/1066	37/18639	0.351351351351351	6.14337508239947	6.4064172406625e-08	1.49602881223881e-05
GO:0046332	SMAD binding	19/1066	79/18639	0.240506329113924	4.20525090840003	6.97774632574074e-08	1.49602881223881e-05
GO:0042277	peptide binding	37/1066	249/18639	0.14859437751004	2.59817129681955	9.14658660358182e-08	1.63419013983995e-05
GO:0140297	DNA-binding transcription factor binding	57/1066	488/18639	0.116803278688525	2.04230423215329	2.31803621034738e-07	3.54990688213199e-05
GO:0005178	integrin binding	27/1066	161/18639	0.167701863354037	2.93226550755713	4.40113815625712e-07	5.89752512938453e-05
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	55/1066	484/18639	0.113636363636364	1.98693075217465	9.0756308588636e-07	0.000108100847563353
GO:0005201	extracellular matrix structural constituent	27/1066	168/18639	0.160714285714286	2.81008777807558	1.04656272422879e-06	0.000112191524037326
GO:0001216	DNA-binding transcription activator activity	55/1066	491/18639	0.112016293279022	1.9586038371742	1.42197974297125e-06	0.000138578389496835
GO:0003779	actin binding	50/1066	443/18639	0.112866817155756	1.97347523918024	3.43717181154489e-06	0.000307054015164677
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	42/1066	349/18639	0.120343839541547	2.10421090545488	4.21268350353706e-06	0.00034738436275321
GO:0001540	amyloid-beta binding	16/1066	83/18639	0.192771084337349	3.37060060127941	1.61151708418918e-05	0.00123396165303629
GO:0050431	transforming growth factor beta binding	8/1066	24/18639	0.333333333333333	5.82833020637899	3.60022730102118e-05	0.00257296244446314
GO:0001784	phosphotyrosine residue binding	11/1066	47/18639	0.234042553191489	4.09223184703206	5.27790237036633e-05	0.00353619458814544
GO:0050840	extracellular matrix binding	13/1066	67/18639	0.194029850746269	3.39261012013105	9.21119265975826e-05	0.00535090354932838
GO:0002020	protease binding	20/1066	136/18639	0.147058823529412	2.57132214987308	9.27095185755951e-05	0.00535090354932838
GO:0044389	ubiquitin-like protein ligase binding	36/1066	322/18639	0.111801242236025	1.95484367170475	9.48387755944396e-05	0.00535090354932838
GO:1990782	protein tyrosine kinase binding	18/1066	117/18639	0.153846153846154	2.6899985567903	0.000113731311120476	0.005924303691137
GO:0032395	MHC class II receptor activity	5/1066	10/18639	0.5	8.74249530956848	0.000119941314024264	0.005924303691137
GO:0031625	ubiquitin protein ligase binding	34/1066	302/18639	0.112582781456954	1.96850887765118	0.000128168960815674	0.005924303691137
GO:0004197	cysteine-type endopeptidase activity	15/1066	88/18639	0.170454545454545	2.98039612826198	0.000129045406453226	0.005924303691137
GO:0001217	DNA-binding transcription repressor activity	32/1066	278/18639	0.115107913669065	2.01266079069202	0.000132633664726948	0.005924303691137
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	31/1066	268/18639	0.115671641791045	2.02251757161659	0.000153505365416796	0.00658231006907221
GO:0043394	proteoglycan binding	9/1066	37/18639	0.243243243243243	4.25310582627656	0.000183805960209605	0.00757846112864216
GO:0140416	transcription regulator inhibitor activity	8/1066	33/18639	0.242424242424242	4.23878560463926	0.000429178254892396	0.0161583386170035
GO:0033218	amide binding	28/1066	247/18639	0.11336032388664	1.98210419974022	0.000435607281085914	0.0161583386170035
GO:0004879	nuclear receptor activity	11/1066	59/18639	0.186440677966102	3.25991350526282	0.000452192312043008	0.0161583386170035
GO:0045309	protein phosphorylated amino acid binding	11/1066	59/18639	0.186440677966102	3.25991350526282	0.000452192312043008	0.0161583386170035
GO:0098531	ligand-modulated transcription factor activity	11/1066	60/18639	0.183333333333333	3.20558161350844	0.000525524074051683	0.0181729615284969
GO:0019210	kinase inhibitor activity	14/1066	90/18639	0.155555555555556	2.71988742964353	0.000566080975943527	0.0189637126941082
GO:0019838	growth factor binding	18/1066	136/18639	0.132352941176471	2.31418993488577	0.000751456624526183	0.0244109545906687
GO:0005516	calmodulin binding	24/1066	207/18639	0.115942028985507	2.0272452891753	0.000788388995281242	0.024857441262985
GO:0003712	transcription coregulator activity	46/1066	495/18639	0.0929292929292929	1.62486781511172	0.000826580234531527	0.0253169717547942
GO:0004860	protein kinase inhibitor activity	13/1066	84/18639	0.154761904761905	2.70601045296167	0.000924633793469176	0.0268201558660349
GO:0004857	enzyme inhibitor activity	40/1066	416/18639	0.0961538461538462	1.68124909799394	0.000925695678212024	0.0268201558660349
GO:0120283	protein serine/threonine kinase binding	5/1066	15/18639	0.333333333333333	5.82833020637899	0.00112367830830151	0.0316995564868216
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/1066	23/18639	0.260869565217391	4.56130190064442	0.0015014190454464	0.0407362067062984
GO:0005521	lamin binding	5/1066	16/18639	0.3125	5.4640595684803	0.00155800790574462	0.0407362067062984
GO:0070411	I-SMAD binding	5/1066	16/18639	0.3125	5.4640595684803	0.00155800790574462	0.0407362067062984
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/1066	24/18639	0.25	4.37124765478424	0.00190611481349427	0.0475198855829268
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/1066	24/18639	0.25	4.37124765478424	0.00190611481349427	0.0475198855829268
GO:0071889	14-3-3 protein binding	7/1066	33/18639	0.212121212121212	3.70893740405936	0.00226016425178305	0.0538421350646986
GO:0140311	protein sequestering activity	7/1066	33/18639	0.212121212121212	3.70893740405936	0.00226016425178305	0.0538421350646986
GO:0051219	phosphoprotein binding	13/1066	93/18639	0.139784946236559	2.4441384736428	0.00238892930818747	0.0544217053880178
GO:0005518	collagen binding	11/1066	72/18639	0.152777777777778	2.67131801125704	0.00248165843635038	0.0544217053880178
GO:0001851	complement component C3b binding	4/1066	11/18639	0.363636363636364	6.35817840695889	0.00253832581100829	0.0544217053880178
GO:0034713	type I transforming growth factor beta receptor binding	4/1066	11/18639	0.363636363636364	6.35817840695889	0.00253832581100829	0.0544217053880178
GO:0042608	T cell receptor binding	4/1066	11/18639	0.363636363636364	6.35817840695889	0.00253832581100829	0.0544217053880178
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/1066	26/18639	0.230769230769231	4.03499783518545	0.00295649097303365	0.0621442808449427
GO:0003714	transcription corepressor activity	22/1066	204/18639	0.107843137254902	1.88563624324026	0.00319416585425177	0.0658489576107289
GO:0004175	endopeptidase activity	37/1066	405/18639	0.091358024691358	1.59739420471128	0.00339740336194358	0.0662311513592385
GO:0030695	GTPase regulator activity	43/1066	489/18639	0.0879345603271984	1.537534962419	0.00340757887715162	0.0662311513592385
GO:0060589	nucleoside-triphosphatase regulator activity	43/1066	490/18639	0.0877551020408163	1.53439713596508	0.00353562795107494	0.0662311513592385
GO:0140375	immune receptor activity	18/1066	156/18639	0.115384615384615	2.01749891759273	0.00356302540093757	0.0662311513592385
GO:0005520	insulin-like growth factor binding	5/1066	19/18639	0.263157894736842	4.60131332082552	0.00359411865303484	0.0662311513592385
GO:0070003	threonine-type peptidase activity	5/1066	19/18639	0.263157894736842	4.60131332082552	0.00359411865303484	0.0662311513592385
GO:0038024	cargo receptor activity	10/1066	65/18639	0.153846153846154	2.6899985567903	0.003645184636376	0.0662311513592385
GO:0140313	molecular sequestering activity	9/1066	55/18639	0.163636363636364	2.8611802831315	0.00373361806854159	0.0667073094912764
GO:0019207	kinase regulator activity	28/1066	287/18639	0.0975609756097561	1.70585274333044	0.00414675360288227	0.0728740961031114
GO:0046875	ephrin receptor binding	6/1066	28/18639	0.214285714285714	3.74678370410078	0.00438797155546452	0.0758694436686768
GO:0004866	endopeptidase inhibitor activity	18/1066	161/18639	0.111801242236025	1.95484367170475	0.0049770573558928	0.081486419134624
GO:0005035	death receptor activity	4/1066	13/18639	0.307692307692308	5.3799971135806	0.00501688774522872	0.081486419134624
GO:0031994	insulin-like growth factor I binding	4/1066	13/18639	0.307692307692308	5.3799971135806	0.00501688774522872	0.081486419134624
GO:0045159	myosin II binding	4/1066	13/18639	0.307692307692308	5.3799971135806	0.00501688774522872	0.081486419134624
GO:0043236	laminin binding	6/1066	29/18639	0.206896551724138	3.61758426602834	0.00526962219170123	0.0843139550672196
GO:0001221	transcription coregulator binding	14/1066	115/18639	0.121739130434783	2.12860755363406	0.00596198227329172	0.0939888970142459
GO:0005539	glycosaminoglycan binding	24/1066	242/18639	0.0991735537190083	1.73404865644334	0.00620670657013217	0.0964288325098795
GO:0005096	GTPase activator activity	26/1066	271/18639	0.0959409594095941	1.67752677526775	0.00692968249361351	0.106123137616481
GO:0042562	hormone binding	12/1066	94/18639	0.127659574468085	2.23212646201748	0.00722859555900879	0.108045776062244
GO:0070325	lipoprotein particle receptor binding	6/1066	31/18639	0.193548387096774	3.38419173273619	0.00741117657823082	0.108045776062244
GO:0000149	SNARE binding	13/1066	106/18639	0.122641509433962	2.14438564196963	0.00741886971548118	0.108045776062244
GO:0005543	phospholipid binding	42/1066	497/18639	0.0845070422535211	1.47760484105383	0.00745838379534144	0.108045776062244
GO:0030414	peptidase inhibitor activity	18/1066	169/18639	0.106508875739645	1.86230669316252	0.00817124605329834	0.116794343588478
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/1066	23/18639	0.217391304347826	3.80108491720369	0.00860209427445591	0.120124419851307
GO:0051015	actin filament binding	21/1066	209/18639	0.100478468899522	1.75686508613338	0.00869832804766477	0.120124419851307
GO:0050700	CARD domain binding	4/1066	15/18639	0.266666666666667	4.66266416510319	0.0087403962205242	0.120124419851307
GO:0008081	phosphoric diester hydrolase activity	11/1066	87/18639	0.126436781609195	2.21074594035065	0.0105985438791941	0.143818215677165
GO:0005159	insulin-like growth factor receptor binding	4/1066	16/18639	0.25	4.37124765478424	0.011134525658784	0.14556355495386
GO:0140327	flippase activity	4/1066	16/18639	0.25	4.37124765478424	0.011134525658784	0.14556355495386
GO:0140328	floppase activity	4/1066	16/18639	0.25	4.37124765478424	0.011134525658784	0.14556355495386
GO:0016922	nuclear receptor binding	15/1066	137/18639	0.109489051094891	1.91441503129237	0.0117725103309113	0.152049771984782
GO:0001848	complement binding	5/1066	25/18639	0.2	3.49699812382739	0.0123581925796578	0.155460968499101
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	11/1066	89/18639	0.123595505617978	2.16106625629783	0.0124716821743682	0.155460968499101
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	11/1066	89/18639	0.123595505617978	2.16106625629783	0.0124716821743682	0.155460968499101
GO:0005085	guanyl-nucleotide exchange factor activity	22/1066	230/18639	0.0956521739130435	1.67247736356962	0.0127026800332887	0.156520379260753
GO:0140303	intramembrane lipid transporter activity	7/1066	45/18639	0.155555555555556	2.71988742964353	0.013253916559073	0.157711076294435
GO:0005154	epidermal growth factor receptor binding	6/1066	35/18639	0.171428571428571	2.99742696328062	0.013461839100286	0.157711076294435
GO:0140793	histone H2AXY142 phosphatase activity	11/1066	90/18639	0.122222222222222	2.13705440900563	0.0134976727977146	0.157711076294435
GO:0005319	lipid transporter activity	18/1066	178/18639	0.101123595505618	1.76814511878913	0.0135491271063382	0.157711076294435
GO:0008484	sulfuric ester hydrolase activity	4/1066	17/18639	0.235294117647059	4.11411543979693	0.0139131117456514	0.157711076294435
GO:0030169	low-density lipoprotein particle binding	4/1066	17/18639	0.235294117647059	4.11411543979693	0.0139131117456514	0.157711076294435
GO:0070403	NAD+ binding	4/1066	17/18639	0.235294117647059	4.11411543979693	0.0139131117456514	0.157711076294435
GO:0051020	GTPase binding	28/1066	315/18639	0.0888888888888889	1.55422138836773	0.0139762614253464	0.157711076294435
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/1066	26/18639	0.192307692307692	3.36249819598788	0.0145966929621873	0.159669947504743
GO:0050681	nuclear androgen receptor binding	5/1066	26/18639	0.192307692307692	3.36249819598788	0.0145966929621873	0.159669947504743
GO:0050750	low-density lipoprotein particle receptor binding	5/1066	26/18639	0.192307692307692	3.36249819598788	0.0145966929621873	0.159669947504743
GO:0030291	protein serine/threonine kinase inhibitor activity	7/1066	46/18639	0.152173913043478	2.66075944204258	0.0148831429232785	0.160567815989572
GO:1990841	promoter-specific chromatin binding	9/1066	68/18639	0.132352941176471	2.31418993488577	0.0149783410438034	0.160567815989572
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/1066	10/18639	0.3	5.24549718574109	0.0165321992483041	0.168785881849352
GO:0005131	growth hormone receptor binding	3/1066	10/18639	0.3	5.24549718574109	0.0165321992483041	0.168785881849352
GO:0008239	dipeptidyl-peptidase activity	3/1066	10/18639	0.3	5.24549718574109	0.0165321992483041	0.168785881849352
GO:0031434	mitogen-activated protein kinase kinase binding	3/1066	10/18639	0.3	5.24549718574109	0.0165321992483041	0.168785881849352
GO:0070097	delta-catenin binding	3/1066	10/18639	0.3	5.24549718574109	0.0165321992483041	0.168785881849352
GO:0005044	scavenger receptor activity	5/1066	27/18639	0.185185185185185	3.2379612257661	0.017091391502719	0.171233380288923
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/1066	27/18639	0.185185185185185	3.2379612257661	0.017091391502719	0.171233380288923
GO:0005525	GTP binding	32/1066	378/18639	0.0846560846560847	1.4802108460645	0.0174320928727479	0.173029662588757
GO:0061135	endopeptidase regulator activity	18/1066	184/18639	0.0978260869565217	1.71048821274166	0.0184617454226671	0.181568725624762
GO:0061134	peptidase regulator activity	21/1066	226/18639	0.0929203539823009	1.62471151770742	0.0196648275879039	0.191642683402118
GO:0051019	mitogen-activated protein kinase binding	5/1066	28/18639	0.178571428571429	3.12231975341731	0.0198530045347308	0.191733521272355
GO:0043395	heparan sulfate proteoglycan binding	4/1066	19/18639	0.210526315789474	3.68105065666041	0.0206948453477761	0.197349760080771
GO:0019887	protein kinase regulator activity	23/1066	255/18639	0.0901960784313725	1.57707758525549	0.0208027265756783	0.197349760080771
GO:0008234	cysteine-type peptidase activity	18/1066	187/18639	0.0962566844919786	1.68304722537147	0.0213844301139898	0.201088676159624
GO:0048185	activin binding	3/1066	11/18639	0.272727272727273	4.76863380521917	0.0217799017872901	0.201806661941365
GO:0003823	antigen binding	17/1066	174/18639	0.0977011494252874	1.70830368118005	0.021837288045894	0.201806661941365
GO:0019001	guanyl nucleotide binding	33/1066	400/18639	0.0825	1.4425117260788	0.0223127689170877	0.202705832873882
GO:0032561	guanyl ribonucleotide binding	33/1066	400/18639	0.0825	1.4425117260788	0.0223127689170877	0.202705832873882
GO:0003785	actin monomer binding	5/1066	29/18639	0.172413793103448	3.01465355502361	0.0228912091895286	0.206213245808191
GO:0004725	protein tyrosine phosphatase activity	11/1066	98/18639	0.112244897959184	1.96260098786231	0.024144492075615	0.215690795875494
GO:0016209	antioxidant activity	10/1066	86/18639	0.116279069767442	2.03313844408569	0.0247092653480569	0.217107275687107
GO:0030742	GTP-dependent protein binding	4/1066	20/18639	0.2	3.49699812382739	0.0247261901290095	0.217107275687107
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	6/1066	40/18639	0.15	2.62274859287054	0.0250288097127549	0.217107275687107
GO:0005025	transforming growth factor beta receptor activity, type I	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0005026	transforming growth factor beta receptor activity, type II	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0008603	cAMP-dependent protein kinase regulator activity	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0016208	AMP binding	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0016361	activin receptor activity, type I	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0016362	activin receptor activity, type II	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0017002	activin receptor activity	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0035259	nuclear glucocorticoid receptor binding	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0035497	cAMP response element binding	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/1066	12/18639	0.25	4.37124765478424	0.0278277559499017	0.217107275687107
GO:0001530	lipopolysaccharide binding	6/1066	41/18639	0.146341463414634	2.55877911499565	0.0279485112358403	0.217107275687107
GO:0042287	MHC protein binding	6/1066	41/18639	0.146341463414634	2.55877911499565	0.0279485112358403	0.217107275687107
GO:0001846	opsonin binding	4/1066	21/18639	0.19047619047619	3.33047440364514	0.0291984288177693	0.221990891437225
GO:0036122	BMP binding	4/1066	21/18639	0.19047619047619	3.33047440364514	0.0291984288177693	0.221990891437225
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/1066	21/18639	0.19047619047619	3.33047440364514	0.0291984288177693	0.221990891437225
GO:0140296	general transcription initiation factor binding	7/1066	53/18639	0.132075471698113	2.3093383836596	0.0304363686487835	0.229773149235887
GO:0071813	lipoprotein particle binding	5/1066	32/18639	0.15625	2.73202978424015	0.033745665040445	0.249485192574876
GO:0071814	protein-lipid complex binding	5/1066	32/18639	0.15625	2.73202978424015	0.033745665040445	0.249485192574876
GO:0120015	sterol transfer activity	5/1066	32/18639	0.15625	2.73202978424015	0.033745665040445	0.249485192574876
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/1066	13/18639	0.230769230769231	4.03499783518545	0.0346710164113037	0.251130605357551
GO:0070123	transforming growth factor beta receptor activity, type III	3/1066	13/18639	0.230769230769231	4.03499783518545	0.0346710164113037	0.251130605357551
GO:0140333	glycerophospholipid flippase activity	3/1066	13/18639	0.230769230769231	4.03499783518545	0.0346710164113037	0.251130605357551
GO:0031267	small GTPase binding	24/1066	283/18639	0.0848056537102474	1.48282605957345	0.035139080186834	0.252812711142859
GO:0003713	transcription coactivator activity	22/1066	256/18639	0.0859375	1.50261638133208	0.0373756814012051	0.267111536413946
GO:0019956	chemokine binding	5/1066	33/18639	0.151515151515152	2.64924100289954	0.0379648477645603	0.268158408535903
GO:0001223	transcription coactivator binding	6/1066	44/18639	0.136363636363636	2.38431690260959	0.0380224609118072	0.268158408535903
GO:0004602	glutathione peroxidase activity	4/1066	23/18639	0.173913043478261	3.04086793376295	0.0394902778519318	0.27365745728593
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/1066	23/18639	0.173913043478261	3.04086793376295	0.0394902778519318	0.27365745728593
GO:0005548	phospholipid transporter activity	8/1066	68/18639	0.117647058823529	2.05705771989847	0.0395680092157827	0.27365745728593
GO:0008013	beta-catenin binding	11/1066	106/18639	0.10377358490566	1.81448015858968	0.0398857913148267	0.274086976214706
GO:0030971	receptor tyrosine kinase binding	9/1066	81/18639	0.111111111111111	1.94277673545966	0.0413557300006049	0.282377978093302
GO:0008191	metalloendopeptidase inhibitor activity	3/1066	14/18639	0.214285714285714	3.74678370410078	0.0422969468569506	0.285171868117302
GO:0098821	BMP receptor activity	3/1066	14/18639	0.214285714285714	3.74678370410078	0.0422969468569506	0.285171868117302
GO:0019209	kinase activator activity	14/1066	148/18639	0.0945945945945946	1.65398559910755	0.044257562410795	0.296525668152326
GO:0030215	semaphorin receptor binding	4/1066	24/18639	0.166666666666667	2.91416510318949	0.0453154945957975	0.298025829488926
GO:0030552	cAMP binding	4/1066	24/18639	0.166666666666667	2.91416510318949	0.0453154945957975	0.298025829488926
GO:0035035	histone acetyltransferase binding	4/1066	24/18639	0.166666666666667	2.91416510318949	0.0453154945957975	0.298025829488926
GO:0004896	cytokine receptor activity	10/1066	96/18639	0.104166666666667	1.82135318949343	0.0475688638382931	0.310646105566465
GO:0044325	transmembrane transporter binding	13/1066	136/18639	0.0955882352941176	1.6713593974175	0.0478139994575249	0.310646105566465
GO:0043495	protein-membrane adaptor activity	6/1066	47/18639	0.127659574468085	2.23212646201748	0.0501523804465274	0.323875613486009
GO:0051371	muscle alpha-actinin binding	3/1066	15/18639	0.2	3.49699812382739	0.0506860845160572	0.32536217126475
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/1066	25/18639	0.16	2.79759849906191	0.051593075932205	0.327264955025585
GO:0120020	cholesterol transfer activity	4/1066	25/18639	0.16	2.79759849906191	0.051593075932205	0.327264955025585
GO:0140693	molecular condensate scaffold activity	6/1066	48/18639	0.125	2.18562382739212	0.0546655586551606	0.344714581637248
GO:0005200	structural constituent of cytoskeleton	11/1066	112/18639	0.0982142857142857	1.71727586437952	0.055591396703019	0.348502791027113
GO:0004674	protein serine/threonine kinase activity	33/1066	433/18639	0.0762124711316397	1.33257434279797	0.0571284178823747	0.351228700960306
GO:0004713	protein tyrosine kinase activity	13/1066	140/18639	0.0928571428571429	1.623606271777	0.0577996046517646	0.351228700960306
GO:0042805	actinin binding	5/1066	37/18639	0.135135135135135	2.36283657015364	0.0579463006397852	0.351228700960306
GO:0004435	phosphatidylinositol phospholipase C activity	4/1066	26/18639	0.153846153846154	2.6899985567903	0.0583196910176627	0.351228700960306
GO:0005160	transforming growth factor beta receptor binding	4/1066	26/18639	0.153846153846154	2.6899985567903	0.0583196910176627	0.351228700960306
GO:0043548	phosphatidylinositol 3-kinase binding	4/1066	26/18639	0.153846153846154	2.6899985567903	0.0583196910176627	0.351228700960306
GO:0070412	R-SMAD binding	4/1066	26/18639	0.153846153846154	2.6899985567903	0.0583196910176627	0.351228700960306
GO:0001222	transcription corepressor binding	6/1066	49/18639	0.122448979591837	2.14101925948616	0.0594162761246368	0.352307306466933
GO:0016763	pentosyltransferase activity	6/1066	49/18639	0.122448979591837	2.14101925948616	0.0594162761246368	0.352307306466933
GO:0005024	transforming growth factor beta receptor activity	3/1066	16/18639	0.1875	3.27843574108818	0.0598133673292741	0.352307306466933
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/1066	16/18639	0.1875	3.27843574108818	0.0598133673292741	0.352307306466933
GO:0003725	double-stranded RNA binding	8/1066	75/18639	0.106666666666667	1.86506566604128	0.064080309233271	0.375377549169762
GO:0017124	SH3 domain binding	11/1066	115/18639	0.0956521739130435	1.67247736356962	0.064801835252328	0.377541127122259
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/1066	27/18639	0.148148148148148	2.59036898061288	0.0654898300637399	0.379007827564046
GO:0035591	signaling adaptor activity	12/1066	129/18639	0.0930232558139535	1.62651075526855	0.0657606864989856	0.379007827564046
GO:0008238	exopeptidase activity	10/1066	102/18639	0.0980392156862745	1.71421476658205	0.0665450521715036	0.379891114915749
GO:0042578	phosphoric ester hydrolase activity	28/1066	363/18639	0.0771349862258953	1.34870451056704	0.0666226955262695	0.379891114915749
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1066	17/18639	0.176470588235294	3.0855865798477	0.0696491363829075	0.388874344804567
GO:0019198	transmembrane receptor protein phosphatase activity	3/1066	17/18639	0.176470588235294	3.0855865798477	0.0696491363829075	0.388874344804567
GO:0038191	neuropilin binding	3/1066	17/18639	0.176470588235294	3.0855865798477	0.0696491363829075	0.388874344804567
GO:0046965	nuclear retinoid X receptor binding	3/1066	17/18639	0.176470588235294	3.0855865798477	0.0696491363829075	0.388874344804567
GO:0051393	alpha-actinin binding	4/1066	28/18639	0.142857142857143	2.49785580273385	0.0730959676519082	0.406004545714226
GO:0005080	protein kinase C binding	6/1066	52/18639	0.115384615384615	2.01749891759273	0.0750971342136246	0.414969731324771
GO:0061791	GTPase motor activity	5/1066	40/18639	0.125	2.18562382739212	0.0762102693054638	0.416823513752333
GO:1990606	membrane scission GTPase motor activity	5/1066	40/18639	0.125	2.18562382739212	0.0762102693054638	0.416823513752333
GO:0019199	transmembrane receptor protein kinase activity	8/1066	78/18639	0.102564102564103	1.79333237119353	0.0769475587256337	0.418719710425783
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	3/1066	18/18639	0.166666666666667	2.91416510318949	0.0801600251876071	0.430544542051054
GO:0008525	phosphatidylcholine transporter activity	3/1066	18/18639	0.166666666666667	2.91416510318949	0.0801600251876071	0.430544542051054
GO:0017046	peptide hormone binding	6/1066	53/18639	0.113207547169811	1.97943290027966	0.0807985085410512	0.430544542051054
GO:0004181	metallocarboxypeptidase activity	4/1066	29/18639	0.137931034482759	2.41172284401889	0.0811287290058889	0.430544542051054
GO:0004629	phospholipase C activity	4/1066	29/18639	0.137931034482759	2.41172284401889	0.0811287290058889	0.430544542051054
GO:0051087	protein-folding chaperone binding	12/1066	134/18639	0.0895522388059701	1.5658200554451	0.0822551405266036	0.43437197361832
GO:0016755	aminoacyltransferase activity	36/1066	496/18639	0.0725806451612903	1.26907189977607	0.0844520700541639	0.44378734851992
GO:0051287	NAD binding	6/1066	54/18639	0.111111111111111	1.94277673545966	0.0867347432321621	0.45355924265794
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/1066	67/18639	0.104477611940299	1.82679006468595	0.0874087978283332	0.454865200349385
GO:0140789	histone phosphatase activity	12/1066	136/18639	0.0882352941176471	1.54279328992385	0.0895191977391121	0.45527464255312
GO:0035925	mRNA 3'-UTR AU-rich region binding	4/1066	30/18639	0.133333333333333	2.33133208255159	0.0895770570159537	0.45527464255312
GO:0051721	protein phosphatase 2A binding	4/1066	30/18639	0.133333333333333	2.33133208255159	0.0895770570159537	0.45527464255312
GO:0035198	miRNA binding	5/1066	42/18639	0.119047619047619	2.08154650227821	0.0899172218426131	0.45527464255312
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	11/1066	122/18639	0.0901639344262295	1.5765155476271	0.0899639520614866	0.45527464255312
GO:0001618	virus receptor activity	8/1066	81/18639	0.0987654320987654	1.72691265374192	0.0912535664424513	0.45527464255312
GO:0008301	DNA binding, bending	3/1066	19/18639	0.157894736842105	2.76078799249531	0.0913097464075753	0.45527464255312
GO:0030506	ankyrin binding	3/1066	19/18639	0.157894736842105	2.76078799249531	0.0913097464075753	0.45527464255312
GO:0042800	histone H3K4 methyltransferase activity	3/1066	19/18639	0.157894736842105	2.76078799249531	0.0913097464075753	0.45527464255312
GO:0032934	sterol binding	7/1066	68/18639	0.102941176470588	1.79992550491116	0.0928987243904294	0.460796713455307
GO:0004867	serine-type endopeptidase inhibitor activity	9/1066	95/18639	0.0947368421052632	1.65647279549719	0.0932769466602626	0.460796713455307
GO:0140272	exogenous protein binding	8/1066	82/18639	0.0975609756097561	1.70585274333044	0.0963403921880745	0.471567253061358
GO:0008200	ion channel inhibitor activity	5/1066	43/18639	0.116279069767442	2.03313844408569	0.0972167564613435	0.471567253061358
GO:0008375	acetylglucosaminyltransferase activity	5/1066	43/18639	0.116279069767442	2.03313844408569	0.0972167564613435	0.471567253061358
GO:0048156	tau protein binding	5/1066	43/18639	0.116279069767442	2.03313844408569	0.0972167564613435	0.471567253061358
GO:0002039	p53 binding	7/1066	69/18639	0.101449275362319	1.77383962802839	0.0985765783362873	0.476009423317568
GO:0170055	lipid transmembrane transporter activity	6/1066	56/18639	0.107142857142857	1.87339185205039	0.0993022811676432	0.477363432339522
GO:0042288	MHC class I protein binding	3/1066	20/18639	0.15	2.62274859287054	0.103059785750852	0.484237506900416
GO:0097110	scaffold protein binding	7/1066	70/18639	0.1	1.7484990619137	0.104440549180855	0.484237506900416
GO:0016248	channel inhibitor activity	5/1066	44/18639	0.113636363636364	1.98693075217465	0.104805768711284	0.484237506900416
GO:0051059	NF-kappaB binding	4/1066	32/18639	0.125	2.18562382739212	0.107668765744414	0.484237506900416
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0004090	carbonyl reductase (NADPH) activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0004382	GDP phosphatase activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0005031	tumor necrosis factor receptor activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0005528	FK506 binding	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0015279	store-operated calcium channel activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0031419	cobalamin binding	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0035374	chondroitin sulfate binding	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0043422	protein kinase B binding	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0045322	unmethylated CpG binding	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0140999	histone H3K4 trimethyltransferase activity	2/1066	10/18639	0.2	3.49699812382739	0.108411382141884	0.484237506900416
GO:0005126	cytokine receptor binding	21/1066	275/18639	0.0763636363636364	1.33521746546137	0.108915337740999	0.484469884059546
GO:0042826	histone deacetylase binding	11/1066	127/18639	0.0866141732283465	1.51444800638194	0.111123626140036	0.492250112488094
GO:0004715	non-membrane spanning protein tyrosine kinase activity	5/1066	45/18639	0.111111111111111	1.94277673545966	0.112677364025589	0.493020956062986
GO:0008009	chemokine activity	5/1066	45/18639	0.111111111111111	1.94277673545966	0.112677364025589	0.493020956062986
GO:0141110	transporter inhibitor activity	5/1066	45/18639	0.111111111111111	1.94277673545966	0.112677364025589	0.493020956062986
GO:0019787	ubiquitin-like protein transferase activity	34/1066	479/18639	0.0709812108559499	1.24110580595127	0.113896298398888	0.496328584892714
GO:0141003	histone H2AX kinase activity	26/1066	354/18639	0.0734463276836158	1.28420835055808	0.114694329728566	0.497782678012238
GO:0015174	basic amino acid transmembrane transporter activity	3/1066	21/18639	0.142857142857143	2.49785580273385	0.115370011906365	0.498696180498483
GO:0008201	heparin binding	14/1066	172/18639	0.0813953488372093	1.42319691085999	0.116433644491527	0.501272557810914
GO:0004679	AMP-activated protein kinase activity	19/1066	248/18639	0.0766129032258065	1.33957589420807	0.119722225238623	0.509804287032575
GO:0001786	phosphatidylserine binding	6/1066	59/18639	0.101694915254237	1.77813463923427	0.119842052548702	0.509804287032575
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	6/1066	59/18639	0.101694915254237	1.77813463923427	0.119842052548702	0.509804287032575
GO:0004180	carboxypeptidase activity	5/1066	46/18639	0.108695652173913	1.90054245860184	0.120823934554578	0.511949635741138
GO:0140996	histone H3 kinase activity	26/1066	357/18639	0.0728291316526611	1.27341668374667	0.122918419721767	0.514536383221314
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/1066	130/18639	0.0846153846153846	1.47949920623467	0.125081159198813	0.514536383221314
GO:0002162	dystroglycan binding	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0008432	JUN kinase binding	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0019864	IgG binding	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0070697	activin receptor binding	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0140031	phosphorylation-dependent protein binding	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0140537	transcription regulator activator activity	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:1900750	oligopeptide binding	2/1066	11/18639	0.181818181818182	3.17908920347945	0.127662822220683	0.514536383221314
GO:0004407	histone deacetylase activity	3/1066	22/18639	0.136363636363636	2.38431690260959	0.12819921065393	0.514536383221314
GO:0008093	cytoskeletal anchor activity	3/1066	22/18639	0.136363636363636	2.38431690260959	0.12819921065393	0.514536383221314
GO:0033558	protein lysine deacetylase activity	3/1066	22/18639	0.136363636363636	2.38431690260959	0.12819921065393	0.514536383221314
GO:0004721	phosphoprotein phosphatase activity	14/1066	175/18639	0.08	1.39879924953096	0.128634095805328	0.514536383221314
GO:0035173	histone kinase activity	26/1066	360/18639	0.0722222222222222	1.26280487804878	0.131496073509446	0.52402896208969
GO:0106310	protein serine kinase activity	26/1066	361/18639	0.07202216066482	1.25930680359435	0.134433568740409	0.530527624918854
GO:0015026	coreceptor activity	6/1066	61/18639	0.0983606557377049	1.71983514286593	0.134611486919709	0.530527624918854
GO:0019905	syntaxin binding	6/1066	61/18639	0.0983606557377049	1.71983514286593	0.134611486919709	0.530527624918854
GO:0003924	GTPase activity	24/1066	331/18639	0.0725075528700906	1.26779388175011	0.138464244548486	0.54371307749442
GO:0005158	insulin receptor binding	3/1066	23/18639	0.130434782608696	2.28065095032221	0.14150555057423	0.549738894010821
GO:0017022	myosin binding	7/1066	76/18639	0.0921052631578947	1.61045966228893	0.143390339358336	0.549738894010821
GO:0098631	cell adhesion mediator activity	7/1066	76/18639	0.0921052631578947	1.61045966228893	0.143390339358336	0.549738894010821
GO:0008236	serine-type peptidase activity	15/1066	194/18639	0.077319587628866	1.35193226436626	0.145378401891619	0.549738894010821
GO:0035254	glutamate receptor binding	5/1066	49/18639	0.102040816326531	1.78418271623847	0.146827890055661	0.549738894010821
GO:0004875	complement receptor activity	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:0005527	macrolide binding	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:0015132	prostaglandin transmembrane transporter activity	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:0042301	phosphate ion binding	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:0045295	gamma-catenin binding	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:0070008	serine-type exopeptidase activity	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:1990459	transferrin receptor binding	2/1066	12/18639	0.166666666666667	2.91416510318949	0.147629835474839	0.549738894010821
GO:0045296	cadherin binding	24/1066	334/18639	0.0718562874251497	1.25640651155475	0.148111492266194	0.549738894010821
GO:0004033	aldo-keto reductase (NADPH) activity	4/1066	36/18639	0.111111111111111	1.94277673545966	0.148203862284634	0.549738894010821
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/1066	36/18639	0.111111111111111	1.94277673545966	0.148203862284634	0.549738894010821
GO:0005484	SNAP receptor activity	4/1066	36/18639	0.111111111111111	1.94277673545966	0.148203862284634	0.549738894010821
GO:0072341	modified amino acid binding	8/1066	91/18639	0.0879120879120879	1.5371420324516	0.149024634965624	0.550877271321202
GO:0005507	copper ion binding	6/1066	63/18639	0.0952380952380952	1.66523720182257	0.150193406448362	0.553289799699807
GO:0070840	dynein complex binding	3/1066	24/18639	0.125	2.18562382739212	0.155246987142577	0.555126906524039
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	18/1066	243/18639	0.0740740740740741	1.29518449030644	0.157706466710291	0.555126906524039
GO:0030551	cyclic nucleotide binding	4/1066	37/18639	0.108108108108108	1.89026925612291	0.15914417278704	0.555126906524039
GO:0004842	ubiquitin-protein transferase activity	31/1066	449/18639	0.0690423162583519	1.20720425210077	0.160248848064826	0.555126906524039
GO:1901681	sulfur compound binding	20/1066	275/18639	0.0727272727272727	1.27163568139178	0.161131019022525	0.555126906524039
GO:0017171	serine hydrolase activity	15/1066	198/18639	0.0757575757575758	1.32462050144977	0.163098858391532	0.555126906524039
GO:0004676	3-phosphoinositide-dependent protein kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0004711	ribosomal protein S6 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0035175	histone H3S10 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0035979	histone H2AXS139 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0044022	histone H3S28 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0044023	histone H4S1 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0044024	histone H2AS1 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0044025	histone H2BS14 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0072354	histone H3T3 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0072371	histone H2AS121 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0072518	Rho-dependent protein serine/threonine kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0140823	histone H2BS36 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0140855	histone H3S57 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0140995	histone H2A kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0140997	histone H4 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0140998	histone H2B kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:1990244	histone H2AT120 kinase activity	18/1066	245/18639	0.073469387755102	1.2846115556917	0.165857510522485	0.555126906524039
GO:0120013	lipid transfer activity	6/1066	65/18639	0.0923076923076923	1.61399913407418	0.166539509846065	0.555126906524039
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0005172	vascular endothelial growth factor receptor binding	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0017154	semaphorin receptor activity	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0019855	calcium channel inhibitor activity	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0051011	microtubule minus-end binding	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0061459	L-arginine transmembrane transporter activity	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0071714	icosanoid transmembrane transporter activity	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/1066	13/18639	0.153846153846154	2.6899985567903	0.1681678025773	0.555126906524039
GO:0017025	TBP-class protein binding	3/1066	25/18639	0.12	2.09819887429644	0.169381611398537	0.555126906524039
GO:0019211	phosphatase activator activity	3/1066	25/18639	0.12	2.09819887429644	0.169381611398537	0.555126906524039
GO:0042974	nuclear retinoic acid receptor binding	3/1066	25/18639	0.12	2.09819887429644	0.169381611398537	0.555126906524039
GO:0004677	DNA-dependent protein kinase activity	18/1066	246/18639	0.0731707317073171	1.27938955749783	0.170015390288442	0.555126906524039
GO:0140857	histone H3T45 kinase activity	18/1066	246/18639	0.0731707317073171	1.27938955749783	0.170015390288442	0.555126906524039
GO:0043531	ADP binding	4/1066	38/18639	0.105263157894737	1.84052532833021	0.170370104707471	0.555126906524039
GO:0030295	protein kinase activator activity	11/1066	139/18639	0.079136690647482	1.38370429360077	0.172371969429793	0.558256046008271
GO:0140767	enzyme-substrate adaptor activity	11/1066	139/18639	0.079136690647482	1.38370429360077	0.172371969429793	0.558256046008271
GO:0035402	histone H3T11 kinase activity	18/1066	247/18639	0.0728744939271255	1.27420984269014	0.174227438026599	0.560876317010553
GO:0035403	histone H3T6 kinase activity	18/1066	247/18639	0.0728744939271255	1.27420984269014	0.174227438026599	0.560876317010553
GO:0030159	signaling receptor complex adaptor activity	5/1066	52/18639	0.0961538461538462	1.68124909799394	0.174975969862896	0.561599520038996
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/1066	39/18639	0.102564102564103	1.79333237119353	0.181862392461882	0.581434929663616
GO:0008198	ferrous iron binding	3/1066	26/18639	0.115384615384615	2.01749891759273	0.18386794883952	0.581434929663616
GO:0019865	immunoglobulin binding	3/1066	26/18639	0.115384615384615	2.01749891759273	0.18386794883952	0.581434929663616
GO:0030247	polysaccharide binding	3/1066	26/18639	0.115384615384615	2.01749891759273	0.18386794883952	0.581434929663616
GO:0052742	phosphatidylinositol kinase activity	3/1066	26/18639	0.115384615384615	2.01749891759273	0.18386794883952	0.581434929663616
GO:0005246	calcium channel regulator activity	5/1066	53/18639	0.0943396226415094	1.64952741689971	0.184786122083922	0.582619773158718
GO:0004065	arylsulfatase activity	2/1066	14/18639	0.142857142857143	2.49785580273385	0.189146278530692	0.589432588909597
GO:0032036	myosin heavy chain binding	2/1066	14/18639	0.142857142857143	2.49785580273385	0.189146278530692	0.589432588909597
GO:0061665	SUMO ligase activity	2/1066	14/18639	0.142857142857143	2.49785580273385	0.189146278530692	0.589432588909597
GO:1901474	azole transmembrane transporter activity	2/1066	14/18639	0.142857142857143	2.49785580273385	0.189146278530692	0.589432588909597
GO:0004177	aminopeptidase activity	4/1066	40/18639	0.1	1.7484990619137	0.193601517257039	0.601567613042163
GO:0003925	G protein activity	5/1066	54/18639	0.0925925925925926	1.61898061288305	0.194791364823897	0.601776204873826
GO:0015485	cholesterol binding	5/1066	54/18639	0.0925925925925926	1.61898061288305	0.194791364823897	0.601776204873826
GO:0004364	glutathione transferase activity	3/1066	27/18639	0.111111111111111	1.94277673545966	0.198665213686493	0.61198019848253
GO:0019902	phosphatase binding	14/1066	190/18639	0.0736842105263158	1.28836772983114	0.199713272608761	0.613445926179347
GO:0019903	protein phosphatase binding	11/1066	144/18639	0.0763888888888889	1.33565900562852	0.201882180055124	0.618082443323729
GO:0001727	lipid kinase activity	4/1066	41/18639	0.0975609756097561	1.70585274333044	0.205567811959468	0.618082443323729
GO:0017080	sodium channel regulator activity	4/1066	41/18639	0.0975609756097561	1.70585274333044	0.205567811959468	0.618082443323729
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0005041	low-density lipoprotein particle receptor activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0008242	omega peptidase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0015929	hexosaminidase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0016846	carbon-sulfur lyase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0017081	chloride channel regulator activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0031005	filamin binding	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0050780	dopamine receptor binding	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0061578	K63-linked deubiquitinase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0141050	histone H3K deacetylase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0141051	histone H4K deacetylase activity	2/1066	15/18639	0.133333333333333	2.33133208255159	0.210447846840635	0.618082443323729
GO:0019789	SUMO transferase activity	3/1066	28/18639	0.107142857142857	1.87339185205039	0.213733523210643	0.619249559140026
GO:0045499	chemorepellent activity	3/1066	28/18639	0.107142857142857	1.87339185205039	0.213733523210643	0.619249559140026
GO:0046625	sphingolipid binding	3/1066	28/18639	0.107142857142857	1.87339185205039	0.213733523210643	0.619249559140026
GO:0046966	nuclear thyroid hormone receptor binding	3/1066	28/18639	0.107142857142857	1.87339185205039	0.213733523210643	0.619249559140026
GO:0097718	disordered domain specific binding	3/1066	28/18639	0.107142857142857	1.87339185205039	0.213733523210643	0.619249559140026
GO:0019894	kinesin binding	4/1066	42/18639	0.0952380952380952	1.66523720182257	0.217741558287558	0.625788071003383
GO:0048487	beta-tubulin binding	4/1066	42/18639	0.0952380952380952	1.66523720182257	0.217741558287558	0.625788071003383
GO:0051879	Hsp90 protein binding	4/1066	42/18639	0.0952380952380952	1.66523720182257	0.217741558287558	0.625788071003383
GO:0004601	peroxidase activity	5/1066	57/18639	0.087719298245614	1.53377110694184	0.225861216426582	0.647388299490096
GO:0061659	ubiquitin-like protein ligase activity	25/1066	372/18639	0.0672043010752688	1.17506657386673	0.228858004712919	0.651258699968327
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/1066	29/18639	0.103448275862069	1.80879213301417	0.229034076388115	0.651258699968327
GO:0051861	glycolipid binding	3/1066	29/18639	0.103448275862069	1.80879213301417	0.229034076388115	0.651258699968327
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/1066	16/18639	0.125	2.18562382739212	0.231967058199401	0.654391279973048
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/1066	16/18639	0.125	2.18562382739212	0.231967058199401	0.654391279973048
GO:0008142	oxysterol binding	2/1066	16/18639	0.125	2.18562382739212	0.231967058199401	0.654391279973048
GO:0061980	regulatory RNA binding	5/1066	58/18639	0.0862068965517241	1.50732677751181	0.236529677924299	0.665511324763381
GO:0001046	core promoter sequence-specific DNA binding	4/1066	44/18639	0.0909090909090909	1.58954460173972	0.242632807194809	0.679107280874925
GO:0019205	nucleobase-containing compound kinase activity	4/1066	44/18639	0.0909090909090909	1.58954460173972	0.242632807194809	0.679107280874925
GO:0001968	fibronectin binding	3/1066	30/18639	0.1	1.7484990619137	0.2445293007628	0.679107280874925
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/1066	30/18639	0.1	1.7484990619137	0.2445293007628	0.679107280874925
GO:0070566	adenylyltransferase activity	3/1066	30/18639	0.1	1.7484990619137	0.2445293007628	0.679107280874925
GO:0030246	carbohydrate binding	19/1066	280/18639	0.0678571428571429	1.18648150629858	0.252529899138193	0.684809390465312
GO:0004550	nucleoside diphosphate kinase activity	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0008429	phosphatidylethanolamine binding	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0016805	dipeptidase activity	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0017110	nucleoside diphosphate phosphatase activity	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0045125	bioactive lipid receptor activity	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0051787	misfolded protein binding	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0070492	oligosaccharide binding	2/1066	17/18639	0.117647058823529	2.05705771989847	0.253609447774934	0.684809390465312
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/1066	60/18639	0.0833333333333333	1.45708255159475	0.258262421977648	0.695621397889545
GO:0003774	cytoskeletal motor activity	11/1066	153/18639	0.0718954248366013	1.25709082882684	0.259901482703462	0.696535973645278
GO:0061775	cohesin loader activity	11/1066	153/18639	0.0718954248366013	1.25709082882684	0.259901482703462	0.696535973645278
GO:0035091	phosphatidylinositol binding	19/1066	284/18639	0.0669014084507042	1.16977049916761	0.272353071837148	0.714563875395019
GO:0070851	growth factor receptor binding	10/1066	139/18639	0.0719424460431655	1.25791299418252	0.272723963831341	0.714563875395019
GO:0043178	alcohol binding	7/1066	92/18639	0.0760869565217391	1.33037972102129	0.273260785917205	0.714563875395019
GO:0031406	carboxylic acid binding	13/1066	187/18639	0.0695187165775401	1.21553410721273	0.273520456563525	0.714563875395019
GO:0000900	mRNA regulatory element binding translation repressor activity	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0004706	JUN kinase kinase kinase activity	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0016854	racemase and epimerase activity	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0017128	phospholipid scramblase activity	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0030228	lipoprotein particle receptor activity	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0034185	apolipoprotein binding	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0035615	clathrin adaptor activity	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:1901611	phosphatidylglycerol binding	2/1066	18/18639	0.111111111111111	1.94277673545966	0.27529062559835	0.714563875395019
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/1066	32/18639	0.09375	1.63921787054409	0.275960302624569	0.714563875395019
GO:0043425	bHLH transcription factor binding	3/1066	32/18639	0.09375	1.63921787054409	0.275960302624569	0.714563875395019
GO:0005496	steroid binding	8/1066	108/18639	0.0740740740740741	1.29518449030644	0.276796780558008	0.715002768092011
GO:0140359	ABC-type transporter activity	4/1066	47/18639	0.0851063829787234	1.48808430801166	0.281039018242207	0.722479202771333
GO:0140938	histone H3 methyltransferase activity	4/1066	47/18639	0.0851063829787234	1.48808430801166	0.281039018242207	0.722479202771333
GO:0043177	organic acid binding	13/1066	189/18639	0.0687830687830688	1.20267131242741	0.286074812547383	0.733665547968408
GO:0061630	ubiquitin protein ligase activity	23/1066	353/18639	0.0651558073654391	1.139248680567	0.288346622445469	0.737726919478622
GO:0004222	metalloendopeptidase activity	8/1066	110/18639	0.0727272727272727	1.27163568139178	0.293561190135815	0.743290316709378
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/1066	48/18639	0.0833333333333333	1.45708255159475	0.294050898299342	0.743290316709378
GO:0038187	pattern recognition receptor activity	4/1066	48/18639	0.0833333333333333	1.45708255159475	0.294050898299342	0.743290316709378
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/1066	19/18639	0.105263157894737	1.84052532833021	0.296935434914912	0.743290316709378
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1066	19/18639	0.105263157894737	1.84052532833021	0.296935434914912	0.743290316709378
GO:0015245	fatty acid transmembrane transporter activity	2/1066	19/18639	0.105263157894737	1.84052532833021	0.296935434914912	0.743290316709378
GO:0034987	immunoglobulin receptor binding	2/1066	19/18639	0.105263157894737	1.84052532833021	0.296935434914912	0.743290316709378
GO:0050145	nucleoside monophosphate kinase activity	2/1066	19/18639	0.105263157894737	1.84052532833021	0.296935434914912	0.743290316709378
GO:0097001	ceramide binding	2/1066	19/18639	0.105263157894737	1.84052532833021	0.296935434914912	0.743290316709378
GO:0033293	monocarboxylic acid binding	6/1066	79/18639	0.0759493670886076	1.32797397107369	0.297454800250301	0.743290316709378
GO:0004252	serine-type endopeptidase activity	12/1066	176/18639	0.0681818181818182	1.19215845130479	0.306946599546953	0.761923191359757
GO:0048306	calcium-dependent protein binding	6/1066	80/18639	0.075	1.31137429643527	0.307570712699999	0.761923191359757
GO:0030332	cyclin binding	3/1066	34/18639	0.0882352941176471	1.54279328992385	0.307754423375723	0.761923191359757
GO:0051427	hormone receptor binding	3/1066	34/18639	0.0882352941176471	1.54279328992385	0.307754423375723	0.761923191359757
GO:0031490	chromatin DNA binding	9/1066	128/18639	0.0703125	1.22941340290807	0.310413313078775	0.764972578437808
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	9/1066	128/18639	0.0703125	1.22941340290807	0.310413313078775	0.764972578437808
GO:0033192	calmodulin-dependent protein phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0140791	histone H2AXS140 phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:1990439	MAP kinase serine/threonine phosphatase activity	6/1066	81/18639	0.0740740740740741	1.29518449030644	0.317744729372291	0.765487735915033
GO:0001972	retinoic acid binding	2/1066	20/18639	0.1	1.7484990619137	0.318477173710918	0.765487735915033
GO:0016004	phospholipase activator activity	2/1066	20/18639	0.1	1.7484990619137	0.318477173710918	0.765487735915033
GO:0016505	peptidase activator activity involved in apoptotic process	2/1066	20/18639	0.1	1.7484990619137	0.318477173710918	0.765487735915033
GO:0005006	epidermal growth factor receptor activity	4/1066	50/18639	0.08	1.39879924953096	0.320280989570247	0.766386653614519
GO:0048020	CCR chemokine receptor binding	4/1066	50/18639	0.08	1.39879924953096	0.320280989570247	0.766386653614519
GO:0016229	steroid dehydrogenase activity	3/1066	35/18639	0.0857142857142857	1.49871348164031	0.323709393723865	0.769437849383555
GO:0043015	gamma-tubulin binding	3/1066	35/18639	0.0857142857142857	1.49871348164031	0.323709393723865	0.769437849383555
GO:0061631	ubiquitin conjugating enzyme activity	3/1066	35/18639	0.0857142857142857	1.49871348164031	0.323709393723865	0.769437849383555
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	6/1066	82/18639	0.0731707317073171	1.27938955749783	0.327968735789067	0.776120275421369
GO:0033549	MAP kinase phosphatase activity	6/1066	82/18639	0.0731707317073171	1.27938955749783	0.327968735789067	0.776120275421369
GO:0005010	insulin-like growth factor receptor activity	4/1066	51/18639	0.0784313725490196	1.37137181326564	0.333464713306791	0.780142548073137
GO:0031072	heat shock protein binding	9/1066	131/18639	0.0687022900763359	1.20125889749796	0.334546780824417	0.780142548073137
GO:0035401	histone H3Y41 kinase activity	8/1066	115/18639	0.0695652173913043	1.21634717350518	0.336415465776807	0.780142548073137
GO:0140801	histone H2AXY142 kinase activity	8/1066	115/18639	0.0695652173913043	1.21634717350518	0.336415465776807	0.780142548073137
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	6/1066	83/18639	0.072289156626506	1.26397522547978	0.338234707535295	0.780142548073137
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/1066	36/18639	0.0833333333333333	1.45708255159475	0.339664442036522	0.780142548073137
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/1066	36/18639	0.0833333333333333	1.45708255159475	0.339664442036522	0.780142548073137
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/1066	36/18639	0.0833333333333333	1.45708255159475	0.339664442036522	0.780142548073137
GO:0005123	death receptor binding	2/1066	21/18639	0.0952380952380952	1.66523720182257	0.339856874953503	0.780142548073137
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/1066	21/18639	0.0952380952380952	1.66523720182257	0.339856874953503	0.780142548073137
GO:0015125	bile acid transmembrane transporter activity	2/1066	21/18639	0.0952380952380952	1.66523720182257	0.339856874953503	0.780142548073137
GO:0051010	microtubule plus-end binding	2/1066	21/18639	0.0952380952380952	1.66523720182257	0.339856874953503	0.780142548073137
GO:0072542	protein phosphatase activator activity	2/1066	21/18639	0.0952380952380952	1.66523720182257	0.339856874953503	0.780142548073137
GO:0140312	cargo adaptor activity	2/1066	21/18639	0.0952380952380952	1.66523720182257	0.339856874953503	0.780142548073137
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/1066	52/18639	0.0769230769230769	1.34499927839515	0.346672108593782	0.794086539343023
GO:0017018	myosin phosphatase activity	6/1066	84/18639	0.0714285714285714	1.24892790136693	0.348534724986819	0.796650799969872
GO:0019213	deacetylase activity	3/1066	37/18639	0.0810810810810811	1.41770194209219	0.355592701087946	0.81105399056655
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/1066	22/18639	0.0909090909090909	1.58954460173972	0.36102264138346	0.812518646730106
GO:0031683	G-protein beta/gamma-subunit complex binding	2/1066	22/18639	0.0909090909090909	1.58954460173972	0.36102264138346	0.812518646730106
GO:0033691	sialic acid binding	2/1066	22/18639	0.0909090909090909	1.58954460173972	0.36102264138346	0.812518646730106
GO:0140517	protein-RNA adaptor activity	2/1066	22/18639	0.0909090909090909	1.58954460173972	0.36102264138346	0.812518646730106
GO:0008237	metallopeptidase activity	12/1066	184/18639	0.0652173913043478	1.14032547516111	0.361985375873879	0.812518646730106
GO:0000510	H3-H4 histone complex chaperone activity	10/1066	151/18639	0.0662251655629139	1.15794639861834	0.363056372932575	0.812518646730106
GO:0140584	chromatin extrusion motor activity	10/1066	151/18639	0.0662251655629139	1.15794639861834	0.363056372932575	0.812518646730106
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	10/1066	151/18639	0.0662251655629139	1.15794639861834	0.363056372932575	0.812518646730106
GO:0140849	ATP-dependent H2AZ histone chaperone activity	10/1066	151/18639	0.0662251655629139	1.15794639861834	0.363056372932575	0.812518646730106
GO:0016247	channel regulator activity	11/1066	168/18639	0.0654761904761905	1.14485057625302	0.366323540568427	0.818122573936153
GO:0015616	DNA translocase activity	10/1066	152/18639	0.0657894736842105	1.15032833020638	0.370793904207566	0.819585661420225
GO:0140674	ATP-dependent histone chaperone activity	10/1066	152/18639	0.0657894736842105	1.15032833020638	0.370793904207566	0.819585661420225
GO:0005501	retinoid binding	3/1066	38/18639	0.0789473684210526	1.38039399624765	0.371468923634845	0.819585661420225
GO:0019840	isoprenoid binding	3/1066	38/18639	0.0789473684210526	1.38039399624765	0.371468923634845	0.819585661420225
GO:0042162	telomeric DNA binding	3/1066	38/18639	0.0789473684210526	1.38039399624765	0.371468923634845	0.819585661420225
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/1066	70/18639	0.0714285714285714	1.24892790136693	0.37177693799904	0.819585661420225
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	4/1066	54/18639	0.0740740740740741	1.29518449030644	0.373094965273386	0.819585661420225
GO:0050661	NADP binding	4/1066	54/18639	0.0740740740740741	1.29518449030644	0.373094965273386	0.819585661420225
GO:0016779	nucleotidyltransferase activity	9/1066	136/18639	0.0661764705882353	1.15709496744289	0.375399232672121	0.822961099027635
GO:0141108	transporter regulator activity	11/1066	170/18639	0.0647058823529412	1.13138174594416	0.381035024844839	0.828801459949821
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1066	23/18639	0.0869565217391304	1.52043396688147	0.381929030984339	0.828801459949821
GO:0003887	DNA-directed DNA polymerase activity	2/1066	23/18639	0.0869565217391304	1.52043396688147	0.381929030984339	0.828801459949821
GO:0016917	GABA receptor activity	2/1066	23/18639	0.0869565217391304	1.52043396688147	0.381929030984339	0.828801459949821
GO:0043274	phospholipase binding	2/1066	23/18639	0.0869565217391304	1.52043396688147	0.381929030984339	0.828801459949821
GO:0098632	cell-cell adhesion mediator activity	4/1066	55/18639	0.0727272727272727	1.27163568139178	0.386280441609147	0.835317645046288
GO:0000217	DNA secondary structure binding	3/1066	39/18639	0.0769230769230769	1.34499927839515	0.387269467899259	0.835317645046288
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/1066	39/18639	0.0769230769230769	1.34499927839515	0.387269467899259	0.835317645046288
GO:0140597	protein carrier chaperone	12/1066	188/18639	0.0638297872340425	1.11606323100874	0.390056697401647	0.839640119707962
GO:0016791	phosphatase activity	17/1066	273/18639	0.0622710622710623	1.08880893965322	0.394233950035225	0.843225464572404
GO:0042379	chemokine receptor binding	5/1066	72/18639	0.0694444444444444	1.21423545966229	0.394822813025526	0.843225464572404
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/1066	122/18639	0.0655737704918033	1.14655676191062	0.397736141796562	0.843225464572404
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0005540	hyaluronic acid binding	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0019957	C-C chemokine binding	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0050699	WW domain binding	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0060229	lipase activator activity	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1066	24/18639	0.0833333333333333	1.45708255159475	0.402536489515409	0.843225464572404
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3/1066	40/18639	0.075	1.31137429643527	0.402972274708087	0.843225464572404
GO:0140658	ATP-dependent chromatin remodeler activity	10/1066	158/18639	0.0632911392405063	1.10664497589474	0.417469500222376	0.843225464572404
GO:0048029	monosaccharide binding	5/1066	74/18639	0.0675675675675676	1.18141828507682	0.41779149714659	0.843225464572404
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/1066	41/18639	0.0731707317073171	1.27938955749783	0.418556837556662	0.843225464572404
GO:0061650	ubiquitin-like protein conjugating enzyme activity	3/1066	41/18639	0.0731707317073171	1.27938955749783	0.418556837556662	0.843225464572404
GO:0003707	nuclear steroid receptor activity	2/1066	25/18639	0.08	1.39879924953096	0.422810826742963	0.843225464572404
GO:0004709	MAP kinase kinase kinase activity	2/1066	25/18639	0.08	1.39879924953096	0.422810826742963	0.843225464572404
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1066	25/18639	0.08	1.39879924953096	0.422810826742963	0.843225464572404
GO:0019003	GDP binding	5/1066	75/18639	0.0666666666666667	1.1656660412758	0.429223980618767	0.843225464572404
GO:0003689	DNA clamp loader activity	10/1066	160/18639	0.0625	1.09281191369606	0.433049000320692	0.843225464572404
GO:0099106	ion channel regulator activity	10/1066	160/18639	0.0625	1.09281191369606	0.433049000320692	0.843225464572404
GO:0004402	histone acetyltransferase activity	3/1066	42/18639	0.0714285714285714	1.24892790136693	0.434004166731209	0.843225464572404
GO:0008307	structural constituent of muscle	3/1066	42/18639	0.0714285714285714	1.24892790136693	0.434004166731209	0.843225464572404
GO:0016859	cis-trans isomerase activity	3/1066	42/18639	0.0714285714285714	1.24892790136693	0.434004166731209	0.843225464572404
GO:0042056	chemoattractant activity	3/1066	42/18639	0.0714285714285714	1.24892790136693	0.434004166731209	0.843225464572404
GO:0001664	G protein-coupled receptor binding	18/1066	297/18639	0.0606060606060606	1.05969640115982	0.434501867374808	0.843225464572404
GO:0031593	polyubiquitin modification-dependent protein binding	4/1066	59/18639	0.0677966101694915	1.18542309282284	0.438528486199357	0.843225464572404
GO:0070063	RNA polymerase binding	4/1066	59/18639	0.0677966101694915	1.18542309282284	0.438528486199357	0.843225464572404
GO:0070888	E-box binding	4/1066	59/18639	0.0677966101694915	1.18542309282284	0.438528486199357	0.843225464572404
GO:0051213	dioxygenase activity	6/1066	93/18639	0.0645161290322581	1.12806391091206	0.441528155991028	0.843225464572404
GO:0001637	G protein-coupled chemoattractant receptor activity	2/1066	26/18639	0.0769230769230769	1.34499927839515	0.442722733234916	0.843225464572404
GO:0004950	chemokine receptor activity	2/1066	26/18639	0.0769230769230769	1.34499927839515	0.442722733234916	0.843225464572404
GO:0008157	protein phosphatase 1 binding	2/1066	26/18639	0.0769230769230769	1.34499927839515	0.442722733234916	0.843225464572404
GO:0015216	purine nucleotide transmembrane transporter activity	2/1066	26/18639	0.0769230769230769	1.34499927839515	0.442722733234916	0.843225464572404
GO:0030507	spectrin binding	2/1066	26/18639	0.0769230769230769	1.34499927839515	0.442722733234916	0.843225464572404
GO:0000287	magnesium ion binding	14/1066	230/18639	0.0608695652173913	1.06430377681703	0.444437931565536	0.843225464572404
GO:0000182	rDNA binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0001094	TFIID-class transcription factor complex binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0003796	lysozyme activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0004955	prostaglandin receptor activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0005345	purine nucleobase transmembrane transporter activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0005381	iron ion transmembrane transporter activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0005522	profilin binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0008190	eukaryotic initiation factor 4E binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0008519	ammonium channel activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0015643	toxic substance binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0016868	intramolecular phosphotransferase activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0019911	structural constituent of myelin sheath	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0030957	Tat protein binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0032052	bile acid binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0035256	G protein-coupled glutamate receptor binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0042166	acetylcholine binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0042975	peroxisome proliferator activated receptor binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0043121	neurotrophin binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0043208	glycosphingolipid binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0043295	glutathione binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0050308	sugar-phosphatase activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0098505	G-rich strand telomeric DNA binding	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1066	10/18639	0.1	1.7484990619137	0.445157933529622	0.843225464572404
GO:0015631	tubulin binding	23/1066	385/18639	0.0597402597402597	1.04455788114325	0.445210459839534	0.843225464572404
GO:0001653	peptide receptor activity	8/1066	128/18639	0.0625	1.09281191369606	0.450451082670843	0.847411456024217
GO:0003724	RNA helicase activity	5/1066	77/18639	0.0649350649350649	1.13538900124266	0.451942288215656	0.847411456024217
GO:0016757	glycosyltransferase activity	16/1066	267/18639	0.0599250936329588	1.04778970002319	0.460527374807055	0.847411456024217
GO:0035255	ionotropic glutamate receptor binding	2/1066	27/18639	0.0740740740740741	1.29518449030644	0.46224733479879	0.847411456024217
GO:0140713	histone chaperone activity	10/1066	164/18639	0.0609756097560976	1.06615796458152	0.46409645773671	0.847411456024217
GO:0030547	signaling receptor inhibitor activity	3/1066	44/18639	0.0681818181818182	1.19215845130479	0.464418500307413	0.847411456024217
GO:0043014	alpha-tubulin binding	3/1066	44/18639	0.0681818181818182	1.19215845130479	0.464418500307413	0.847411456024217
GO:0016407	acetyltransferase activity	6/1066	96/18639	0.0625	1.09281191369606	0.472103363948286	0.847411456024217
GO:0008186	ATP-dependent activity, acting on RNA	5/1066	79/18639	0.0632911392405063	1.10664497589474	0.474411760727569	0.847411456024217
GO:0004016	adenylate cyclase activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0004954	prostanoid receptor activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0005114	type II transforming growth factor beta receptor binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0005225	volume-sensitive anion channel activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0008172	S-methyltransferase activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0008199	ferric iron binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0008503	benzodiazepine receptor activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0008526	phosphatidylinositol transfer activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0015205	nucleobase transmembrane transporter activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0019203	carbohydrate phosphatase activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0019215	intermediate filament binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0032050	clathrin heavy chain binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0034056	estrogen response element binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0045294	alpha-catenin binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0050786	RAGE receptor binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0050998	nitric-oxide synthase binding	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0097493	structural molecule activity conferring elasticity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1066	11/18639	0.0909090909090909	1.58954460173972	0.476907444660516	0.847411456024217
GO:0036408	histone H3K14 acetyltransferase activity	2/1066	28/18639	0.0714285714285714	1.24892790136693	0.481363781844032	0.847411456024217
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	8/1066	132/18639	0.0606060606060606	1.05969640115982	0.485193820548984	0.847411456024217
GO:1901981	phosphatidylinositol phosphate binding	11/1066	185/18639	0.0594594594594595	1.0396480908676	0.491623803545113	0.847411456024217
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3/1066	46/18639	0.0652173913043478	1.14032547516111	0.494092048745586	0.847411456024217
GO:0030276	clathrin binding	3/1066	46/18639	0.0652173913043478	1.14032547516111	0.494092048745586	0.847411456024217
GO:0010484	histone H3 acetyltransferase activity	2/1066	29/18639	0.0689655172413793	1.20586142200945	0.500054871137063	0.847411456024217
GO:0035250	UDP-galactosyltransferase activity	2/1066	29/18639	0.0689655172413793	1.20586142200945	0.500054871137063	0.847411456024217
GO:0046906	tetrapyrrole binding	9/1066	152/18639	0.0592105263157895	1.03529549718574	0.506424379450628	0.847411456024217
GO:0004000	adenosine deaminase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0004032	aldose reductase (NADPH) activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0004126	cytidine deaminase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0004859	phospholipase inhibitor activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0005078	MAP-kinase scaffold activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0005165	neurotrophin receptor binding	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0015166	polyol transmembrane transporter activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0015269	calcium-activated potassium channel activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0015368	calcium:monoatomic cation antiporter activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0016801	hydrolase activity, acting on ether bonds	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0016803	ether hydrolase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0016840	carbon-nitrogen lyase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0017166	vinculin binding	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0031543	peptidyl-proline dioxygenase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0035251	UDP-glucosyltransferase activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0043047	single-stranded telomeric DNA binding	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0070410	co-SMAD binding	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0097677	STAT family protein binding	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1066	12/18639	0.0833333333333333	1.45708255159475	0.506841772768305	0.847411456024217
GO:0061733	protein-lysine-acetyltransferase activity	3/1066	47/18639	0.0638297872340425	1.11606323100874	0.508618391734453	0.847411456024217
GO:0043130	ubiquitin binding	6/1066	100/18639	0.06	1.04909943714822	0.512086214395613	0.847411456024217
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0015215	nucleotide transmembrane transporter activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0031210	phosphatidylcholine binding	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0032452	histone demethylase activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0033612	receptor serine/threonine kinase binding	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0043995	histone H4K5 acetyltransferase activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0043996	histone H4K8 acetyltransferase activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0043997	histone H4K12 acetyltransferase activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0048019	receptor antagonist activity	2/1066	30/18639	0.0666666666666667	1.1656660412758	0.518306697592367	0.847411456024217
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1066	48/18639	0.0625	1.09281191369606	0.522922891296794	0.847411456024217
GO:0008235	metalloexopeptidase activity	4/1066	66/18639	0.0606060606060606	1.05969640115982	0.526286513357979	0.847411456024217
GO:0004386	helicase activity	9/1066	155/18639	0.0580645161290323	1.01525751982086	0.530274702946848	0.847411456024217
GO:0140030	modification-dependent protein binding	10/1066	173/18639	0.0578034682080925	1.01069309937208	0.532612378576696	0.847411456024217
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0004535	poly(A)-specific ribonuclease activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0008035	high-density lipoprotein particle binding	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0008417	fucosyltransferase activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0019104	DNA N-glycosylase activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0035325	Toll-like receptor binding	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0039706	co-receptor binding	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0043560	insulin receptor substrate binding	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0046974	histone H3K9 methyltransferase activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0046975	histone H3K36 methyltransferase activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0071837	HMG box domain binding	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0089720	caspase binding	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0140852	histone ubiquitin ligase activity	1/1066	13/18639	0.0769230769230769	1.34499927839515	0.535064603617555	0.847411456024217
GO:0008327	methyl-CpG binding	2/1066	31/18639	0.0645161290322581	1.12806391091206	0.536108333906181	0.847411456024217
GO:0140457	protein demethylase activity	2/1066	31/18639	0.0645161290322581	1.12806391091206	0.536108333906181	0.847411456024217
GO:0005004	GPI-linked ephrin receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0005008	hepatocyte growth factor receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0005009	insulin receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0005011	macrophage colony-stimulating factor receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0005020	stem cell factor receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0008288	boss receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0036332	placental growth factor receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0038062	protein tyrosine kinase collagen receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0060175	brain-derived neurotrophic factor receptor activity	3/1066	49/18639	0.0612244897959184	1.07050962974308	0.536995858908258	0.847411456024217
GO:0016500	protein-hormone receptor activity	4/1066	67/18639	0.0597014925373134	1.0438800369634	0.538289804636733	0.847411456024217
GO:0042054	histone methyltransferase activity	4/1066	67/18639	0.0597014925373134	1.0438800369634	0.538289804636733	0.847411456024217
GO:0004722	protein serine/threonine phosphatase activity	6/1066	103/18639	0.058252427184466	1.01854314286235	0.541307006162925	0.847411456024217
GO:0030145	manganese ion binding	4/1066	68/18639	0.0588235294117647	1.02852885994923	0.550137193539968	0.847411456024217
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	5/1066	86/18639	0.0581395348837209	1.01656922204285	0.550292291481817	0.847411456024217
GO:0005007	fibroblast growth factor receptor activity	3/1066	50/18639	0.06	1.04909943714822	0.550828722908557	0.847411456024217
GO:0005017	platelet-derived growth factor receptor activity	3/1066	50/18639	0.06	1.04909943714822	0.550828722908557	0.847411456024217
GO:0005019	platelet-derived growth factor beta-receptor activity	3/1066	50/18639	0.06	1.04909943714822	0.550828722908557	0.847411456024217
GO:0015605	organophosphate ester transmembrane transporter activity	3/1066	50/18639	0.06	1.04909943714822	0.550828722908557	0.847411456024217
GO:0032813	tumor necrosis factor receptor superfamily binding	3/1066	50/18639	0.06	1.04909943714822	0.550828722908557	0.847411456024217
GO:0008528	G protein-coupled peptide receptor activity	7/1066	122/18639	0.0573770491803279	1.00323716667179	0.551700604387666	0.847411456024217
GO:0008378	galactosyltransferase activity	2/1066	32/18639	0.0625	1.09281191369606	0.553451535991623	0.847411456024217
GO:0031369	translation initiation factor binding	2/1066	32/18639	0.0625	1.09281191369606	0.553451535991623	0.847411456024217
GO:0042910	xenobiotic transmembrane transporter activity	2/1066	32/18639	0.0625	1.09281191369606	0.553451535991623	0.847411456024217
GO:0005161	platelet-derived growth factor receptor binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0005347	ATP transmembrane transporter activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0005545	1-phosphatidylinositol binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0008195	phosphatidate phosphatase activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0008559	ABC-type xenobiotic transporter activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0019763	immunoglobulin receptor activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0032454	histone H3K9 demethylase activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0034236	protein kinase A catalytic subunit binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0042043	neurexin family protein binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0042813	Wnt receptor activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0044548	S100 protein binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0046030	inositol trisphosphate phosphatase activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0061783	peptidoglycan muralytic activity	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0070742	C2H2 zinc finger domain binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0098847	sequence-specific single stranded DNA binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:1901612	cardiolipin binding	1/1066	14/18639	0.0714285714285714	1.24892790136693	0.561673705547314	0.847411456024217
GO:0008080	N-acetyltransferase activity	4/1066	69/18639	0.0579710144927536	1.01362264458765	0.561822611579556	0.847411456024217
GO:0016279	protein-lysine N-methyltransferase activity	4/1066	69/18639	0.0579710144927536	1.01362264458765	0.561822611579556	0.847411456024217
GO:0005021	vascular endothelial growth factor receptor activity	3/1066	51/18639	0.0588235294117647	1.02852885994923	0.564413973508667	0.847411456024217
GO:0005030	neurotrophin receptor activity	3/1066	51/18639	0.0588235294117647	1.02852885994923	0.564413973508667	0.847411456024217
GO:0005048	signal sequence binding	3/1066	51/18639	0.0588235294117647	1.02852885994923	0.564413973508667	0.847411456024217
GO:0016597	amino acid binding	3/1066	51/18639	0.0588235294117647	1.02852885994923	0.564413973508667	0.847411456024217
GO:0019239	deaminase activity	2/1066	33/18639	0.0606060606060606	1.05969640115982	0.57033047231617	0.851161134098942
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/1066	88/18639	0.0568181818181818	0.993465376087327	0.570990730289249	0.851161134098942
GO:0016278	lysine N-methyltransferase activity	4/1066	70/18639	0.0571428571428571	0.999142321093541	0.573340531190496	0.851161134098942
GO:0005125	cytokine activity	13/1066	234/18639	0.0555555555555556	0.971388367729831	0.583573880211415	0.851161134098942
GO:0008083	growth factor activity	9/1066	162/18639	0.0555555555555556	0.971388367729831	0.58419092281356	0.851161134098942
GO:0140299	molecular sensor activity	4/1066	71/18639	0.0563380281690141	0.985069894035885	0.584685949050315	0.851161134098942
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1066	34/18639	0.0588235294117647	1.02852885994923	0.586741475374948	0.851161134098942
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1066	34/18639	0.0588235294117647	1.02852885994923	0.586741475374948	0.851161134098942
GO:0090482	vitamin transmembrane transporter activity	2/1066	34/18639	0.0588235294117647	1.02852885994923	0.586741475374948	0.851161134098942
GO:0000774	adenyl-nucleotide exchange factor activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0004089	carbonate dehydratase activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0004129	cytochrome-c oxidase activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0004953	icosanoid receptor activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0005523	tropomyosin binding	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0010181	FMN binding	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0015250	water channel activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0030553	cGMP binding	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0031386	protein tag activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0033130	acetylcholine receptor binding	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0042809	nuclear vitamin D receptor binding	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0045504	dynein heavy chain binding	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0048531	beta-1,3-galactosyltransferase activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0140776	protein-containing complex destabilizing activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0141047	molecular tag activity	1/1066	15/18639	0.0666666666666667	1.1656660412758	0.586761266883505	0.851161134098942
GO:0005003	ephrin receptor activity	3/1066	53/18639	0.0566037735849057	0.989716450139828	0.590816577111049	0.851284100353555
GO:0005005	transmembrane-ephrin receptor activity	3/1066	53/18639	0.0566037735849057	0.989716450139828	0.590816577111049	0.851284100353555
GO:0005544	calcium-dependent phospholipid binding	3/1066	53/18639	0.0566037735849057	0.989716450139828	0.590816577111049	0.851284100353555
GO:0034212	protein N-acetyltransferase activity	3/1066	53/18639	0.0566037735849057	0.989716450139828	0.590816577111049	0.851284100353555
GO:0038064	collagen receptor activity	3/1066	53/18639	0.0566037735849057	0.989716450139828	0.590816577111049	0.851284100353555
GO:0008194	UDP-glycosyltransferase activity	8/1066	145/18639	0.0551724137931034	0.964689137607556	0.592902266215775	0.853142589776257
GO:0004620	phospholipase activity	6/1066	109/18639	0.055045871559633	0.962476547842402	0.597284827963017	0.858296696483048
GO:0016887	ATP hydrolysis activity	23/1066	417/18639	0.0551558752997602	0.964399962206595	0.602451001073728	0.858745456097649
GO:0010485	histone H4 acetyltransferase activity	2/1066	35/18639	0.0571428571428571	0.999142321093541	0.602682813656831	0.858745456097649
GO:0034061	DNA polymerase activity	2/1066	35/18639	0.0571428571428571	0.999142321093541	0.602682813656831	0.858745456097649
GO:0140463	chromatin-protein adaptor activity	3/1066	54/18639	0.0555555555555556	0.971388367729831	0.603623730748559	0.858745456097649
GO:0043539	protein serine/threonine kinase activator activity	4/1066	73/18639	0.0547945205479452	0.958081677760929	0.60684178340234	0.858745456097649
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0015562	efflux transmembrane transporter activity	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0016722	oxidoreductase activity, acting on metal ions	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0019841	retinol binding	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0055102	lipase inhibitor activity	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:0097027	ubiquitin-protein transferase activator activity	1/1066	16/18639	0.0625	1.09281191369606	0.610414214129112	0.858745456097649
GO:1902936	phosphatidylinositol bisphosphate binding	6/1066	111/18639	0.0540540540540541	0.945134628061457	0.615114260935977	0.862230319438993
GO:0003684	damaged DNA binding	4/1066	74/18639	0.0540540540540541	0.945134628061457	0.617644656902669	0.862230319438993
GO:0004190	aspartic-type endopeptidase activity	2/1066	36/18639	0.0555555555555556	0.971388367729831	0.618154482575673	0.862230319438993
GO:0016409	palmitoyltransferase activity	2/1066	36/18639	0.0555555555555556	0.971388367729831	0.618154482575673	0.862230319438993
GO:0045505	dynein intermediate chain binding	2/1066	36/18639	0.0555555555555556	0.971388367729831	0.618154482575673	0.862230319438993
GO:0055106	ubiquitin-protein transferase regulator activity	2/1066	36/18639	0.0555555555555556	0.971388367729831	0.618154482575673	0.862230319438993
GO:0008017	microtubule binding	15/1066	276/18639	0.0543478260869565	0.950271229300922	0.618521563105024	0.862230319438993
GO:0016298	lipase activity	7/1066	130/18639	0.0538461538461538	0.941499494876606	0.619456189198045	0.862411733532863
GO:0044183	protein folding chaperone	4/1066	75/18639	0.0533333333333333	0.932532833020638	0.628259906270776	0.870186397280181
GO:0016410	N-acyltransferase activity	5/1066	94/18639	0.0531914893617021	0.930052692507285	0.629938080418756	0.870186397280181
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:0015278	intracellularly gated calcium channel activity	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:0016018	cyclosporin A binding	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:0030548	acetylcholine receptor regulator activity	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:0031489	myosin V binding	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:0048038	quinone binding	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:1990226	histone methyltransferase binding	1/1066	17/18639	0.0588235294117647	1.02852885994923	0.632714512026249	0.870186397280181
GO:0070001	aspartic-type peptidase activity	2/1066	37/18639	0.0540540540540541	0.945134628061457	0.6331580129464	0.870186397280181
GO:0008276	protein methyltransferase activity	5/1066	95/18639	0.0526315789473684	0.920262664165103	0.639270283924855	0.87746190059852
GO:0016504	peptidase activator activity	3/1066	57/18639	0.0526315789473684	0.920262664165103	0.64042520791677	0.877923047169792
GO:0000146	microfilament motor activity	2/1066	38/18639	0.0526315789473684	0.920262664165103	0.647696295685931	0.87930826433073
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	3/1066	58/18639	0.0517241379310345	0.904396066507084	0.652144792670606	0.87930826433073
GO:0000400	four-way junction DNA binding	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0005372	water transmembrane transporter activity	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0017075	syntaxin-1 binding	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0022851	GABA-gated chloride ion channel activity	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0031690	adrenergic receptor binding	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0032393	MHC class I receptor activity	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0050811	GABA receptor binding	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0070064	proline-rich region binding	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0098641	cadherin binding involved in cell-cell adhesion	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0099602	neurotransmitter receptor regulator activity	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:1990381	ubiquitin-specific protease binding	1/1066	18/18639	0.0555555555555556	0.971388367729831	0.653739446522007	0.87930826433073
GO:0019208	phosphatase regulator activity	6/1066	117/18639	0.0512820512820513	0.896666185596767	0.665829747818234	0.88511361978737
GO:0008170	N-methyltransferase activity	5/1066	98/18639	0.0510204081632653	0.892091358119233	0.666376519567667	0.88511361978737
GO:0042626	ATPase-coupled transmembrane transporter activity	5/1066	98/18639	0.0510204081632653	0.892091358119233	0.666376519567667	0.88511361978737
GO:0140104	molecular carrier activity	13/1066	249/18639	0.0522088353413655	0.912870996179841	0.672546588562827	0.88511361978737
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0004890	GABA-A receptor activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0016918	retinal binding	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0042577	lipid phosphatase activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0042834	peptidoglycan binding	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0046527	glucosyltransferase activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0046624	sphingolipid transporter activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0140036	ubiquitin-modified protein reader activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:1990380	K48-linked deubiquitinase activity	1/1066	19/18639	0.0526315789473684	0.920262664165103	0.67356189161129	0.88511361978737
GO:0001098	basal transcription machinery binding	3/1066	60/18639	0.05	0.874249530956848	0.674756096518142	0.88511361978737
GO:0001099	basal RNA polymerase II transcription machinery binding	3/1066	60/18639	0.05	0.874249530956848	0.674756096518142	0.88511361978737
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	3/1066	60/18639	0.05	0.874249530956848	0.674756096518142	0.88511361978737
GO:0015036	disulfide oxidoreductase activity	2/1066	40/18639	0.05	0.874249530956848	0.67539453450193	0.88511361978737
GO:0030331	nuclear estrogen receptor binding	2/1066	40/18639	0.05	0.874249530956848	0.67539453450193	0.88511361978737
GO:0032451	demethylase activity	2/1066	40/18639	0.05	0.874249530956848	0.67539453450193	0.88511361978737
GO:0050997	quaternary ammonium group binding	2/1066	40/18639	0.05	0.874249530956848	0.67539453450193	0.88511361978737
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/1066	61/18639	0.0491803278688525	0.859917571432965	0.685647771278042	0.890867468625005
GO:0015101	organic cation transmembrane transporter activity	4/1066	81/18639	0.0493827160493827	0.863456326870961	0.687891043120344	0.890867468625005
GO:0042169	SH2 domain binding	2/1066	41/18639	0.0487804878048781	0.852926371665218	0.688565698447841	0.890867468625005
GO:0140828	metal cation:monoatomic cation antiporter activity	2/1066	41/18639	0.0487804878048781	0.852926371665218	0.688565698447841	0.890867468625005
GO:0032182	ubiquitin-like protein binding	6/1066	120/18639	0.05	0.874249530956848	0.689542688115992	0.890867468625005
GO:0001614	purinergic nucleotide receptor activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0015095	magnesium ion transmembrane transporter activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0015464	acetylcholine receptor activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0016502	nucleotide receptor activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0031418	L-ascorbic acid binding	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0043024	ribosomal small subunit binding	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0052745	inositol phosphate phosphatase activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0061608	nuclear import signal receptor activity	1/1066	20/18639	0.05	0.874249530956848	0.692250560974468	0.890867468625005
GO:0016758	hexosyltransferase activity	10/1066	197/18639	0.050761421319797	0.887562975590709	0.695874298905541	0.893886657792367
GO:0015179	L-amino acid transmembrane transporter activity	3/1066	62/18639	0.0483870967741935	0.846047933184046	0.696264327664764	0.893886657792367
GO:0051082	unfolded protein binding	6/1066	121/18639	0.0495867768595041	0.867024328221668	0.697195354738798	0.894011268277502
GO:0030165	PDZ domain binding	4/1066	83/18639	0.0481927710843374	0.842650150319854	0.706192268858845	0.900333806386716
GO:0020037	heme binding	7/1066	142/18639	0.0492957746478873	0.861936157281399	0.709573356387662	0.900333806386716
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/1066	21/18639	0.0476190476190476	0.832618600911284	0.709870245275516	0.900333806386716
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/1066	21/18639	0.0476190476190476	0.832618600911284	0.709870245275516	0.900333806386716
GO:0009975	cyclase activity	1/1066	21/18639	0.0476190476190476	0.832618600911284	0.709870245275516	0.900333806386716
GO:0035613	RNA stem-loop binding	1/1066	21/18639	0.0476190476190476	0.832618600911284	0.709870245275516	0.900333806386716
GO:0061891	calcium ion sensor activity	1/1066	21/18639	0.0476190476190476	0.832618600911284	0.709870245275516	0.900333806386716
GO:0070182	DNA polymerase binding	1/1066	21/18639	0.0476190476190476	0.832618600911284	0.709870245275516	0.900333806386716
GO:0046982	protein heterodimerization activity	19/1066	369/18639	0.0514905149051491	0.900311170091063	0.715066878092293	0.900333806386716
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/1066	44/18639	0.0454545454545455	0.794772300869862	0.725451446846762	0.900333806386716
GO:0160215	deacylase activity	3/1066	65/18639	0.0461538461538462	0.806999567037091	0.726478068447613	0.900333806386716
GO:0008970	phospholipase A1 activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0015377	chloride:monoatomic cation symporter activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0032931	histone H3K56 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0043992	histone H3K9 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0043993	histone H3K18 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0043994	histone H3K23 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0043999	histone H2AK5 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0044012	histone H2AK9 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0044014	histone H2BK5 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0044015	histone H2BK12 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0044016	histone H3K4 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0044017	histone H3K27 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0044018	histone H3K36 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0046972	histone H4K16 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0050321	tau-protein kinase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0140035	ubiquitin-like protein reader activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0140784	metal ion sensor activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0140908	histone H3K122 acetyltransferase activity	1/1066	22/18639	0.0454545454545455	0.794772300869862	0.726482035937043	0.900333806386716
GO:0046915	transition metal ion transmembrane transporter activity	2/1066	45/18639	0.0444444444444444	0.777110694183865	0.736897806110083	0.905094278459433
GO:0019888	protein phosphatase regulator activity	5/1066	107/18639	0.0467289719626168	0.817055636408269	0.739415415541487	0.905094278459433
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0005212	structural constituent of eye lens	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0008171	O-methyltransferase activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0016493	C-C chemokine receptor activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0016849	phosphorus-oxygen lyase activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0017134	fibroblast growth factor binding	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0031681	G-protein beta-subunit binding	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0042171	lysophosphatidic acid acyltransferase activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0044013	histone H2B acetyltransferase activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0070577	lysine-acetylated histone binding	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0071617	lysophospholipid acyltransferase activity	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0140103	catalytic activity, acting on a glycoprotein	1/1066	23/18639	0.0434782608695652	0.760216983440737	0.742143536162165	0.905094278459433
GO:0004843	cysteine-type deubiquitinase activity	5/1066	108/18639	0.0462962962962963	0.809490306441526	0.746755626728727	0.909684127105904
GO:0046943	carboxylic acid transmembrane transporter activity	9/1066	188/18639	0.0478723404255319	0.837047423256557	0.754257119669662	0.913058592052883
GO:0003777	microtubule motor activity	3/1066	68/18639	0.0441176470588235	0.771396644961925	0.754285733909859	0.913058592052883
GO:0004622	lysophospholipase activity	1/1066	24/18639	0.0416666666666667	0.728541275797373	0.756909059929416	0.913058592052883
GO:0005315	phosphate transmembrane transporter activity	1/1066	24/18639	0.0416666666666667	0.728541275797373	0.756909059929416	0.913058592052883
GO:0043998	histone H2A acetyltransferase activity	1/1066	24/18639	0.0416666666666667	0.728541275797373	0.756909059929416	0.913058592052883
GO:0070300	phosphatidic acid binding	1/1066	24/18639	0.0416666666666667	0.728541275797373	0.756909059929416	0.913058592052883
GO:0140033	acetylation-dependent protein binding	1/1066	24/18639	0.0416666666666667	0.728541275797373	0.756909059929416	0.913058592052883
GO:0005504	fatty acid binding	2/1066	47/18639	0.0425531914893617	0.744042154005828	0.758570699876406	0.913058592052883
GO:0061749	forked DNA-dependent helicase activity	2/1066	47/18639	0.0425531914893617	0.744042154005828	0.758570699876406	0.913058592052883
GO:1990518	single-stranded 3'-5' DNA helicase activity	2/1066	47/18639	0.0425531914893617	0.744042154005828	0.758570699876406	0.913058592052883
GO:0005342	organic acid transmembrane transporter activity	9/1066	189/18639	0.0476190476190476	0.832618600911284	0.759696347547658	0.913058592052883
GO:0042393	histone binding	12/1066	247/18639	0.048582995951417	0.849473228460095	0.759746515029078	0.913058592052883
GO:0008094	ATP-dependent activity, acting on DNA	10/1066	210/18639	0.0476190476190476	0.832618600911284	0.767707932925852	0.914926479763977
GO:0009378	four-way junction helicase activity	2/1066	48/18639	0.0416666666666667	0.728541275797373	0.768816256771171	0.914926479763977
GO:0036121	double-stranded DNA helicase activity	2/1066	48/18639	0.0416666666666667	0.728541275797373	0.768816256771171	0.914926479763977
GO:0043138	3'-5' DNA helicase activity	2/1066	48/18639	0.0416666666666667	0.728541275797373	0.768816256771171	0.914926479763977
GO:0000030	mannosyltransferase activity	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0008139	nuclear localization sequence binding	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0015662	P-type ion transporter activity	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0019707	protein-cysteine S-acyltransferase activity	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0140358	P-type transmembrane transporter activity	1/1066	25/18639	0.04	0.699399624765478	0.770829819645518	0.914926479763977
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4/1066	91/18639	0.043956043956044	0.768571016225801	0.77154247920395	0.914926479763977
GO:0008514	organic anion transmembrane transporter activity	13/1066	269/18639	0.0483271375464684	0.844999546649742	0.772517599520258	0.915070570923444
GO:0060590	ATPase regulator activity	2/1066	49/18639	0.0408163265306122	0.713673086495386	0.778680954552572	0.920480611747297
GO:0005112	Notch binding	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0005227	calcium-activated cation channel activity	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0008143	poly(A) binding	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0051139	metal cation:proton antiporter activity	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0070006	metalloaminopeptidase activity	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0097602	cullin family protein binding	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0120014	phospholipid transfer activity	1/1066	26/18639	0.0384615384615385	0.672499639197575	0.783954103101942	0.920480611747297
GO:0015297	antiporter activity	6/1066	135/18639	0.0444444444444444	0.777110694183865	0.790927250250427	0.927652092197438
GO:0101005	deubiquitinase activity	5/1066	115/18639	0.0434782608695652	0.760216983440737	0.793872002838917	0.927894582662136
GO:0001671	ATPase activator activity	1/1066	27/18639	0.037037037037037	0.647592245153221	0.796327440344371	0.927894582662136
GO:0005385	zinc ion transmembrane transporter activity	1/1066	27/18639	0.037037037037037	0.647592245153221	0.796327440344371	0.927894582662136
GO:0008266	poly(U) RNA binding	1/1066	27/18639	0.037037037037037	0.647592245153221	0.796327440344371	0.927894582662136
GO:0008320	protein transmembrane transporter activity	1/1066	27/18639	0.037037037037037	0.647592245153221	0.796327440344371	0.927894582662136
GO:0008395	steroid hydroxylase activity	1/1066	27/18639	0.037037037037037	0.647592245153221	0.796327440344371	0.927894582662136
GO:0035064	methylated histone binding	3/1066	74/18639	0.0405405405405405	0.708850971046093	0.803037041210204	0.934377820737538
GO:0005242	inward rectifier potassium channel activity	1/1066	28/18639	0.0357142857142857	0.624463950683463	0.807992761029569	0.934377820737538
GO:0016866	intramolecular transferase activity	1/1066	28/18639	0.0357142857142857	0.624463950683463	0.807992761029569	0.934377820737538
GO:0050698	proteoglycan sulfotransferase activity	1/1066	28/18639	0.0357142857142857	0.624463950683463	0.807992761029569	0.934377820737538
GO:0051959	dynein light intermediate chain binding	1/1066	28/18639	0.0357142857142857	0.624463950683463	0.807992761029569	0.934377820737538
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/1066	28/18639	0.0357142857142857	0.624463950683463	0.807992761029569	0.934377820737538
GO:0141052	histone H3 demethylase activity	1/1066	28/18639	0.0357142857142857	0.624463950683463	0.807992761029569	0.934377820737538
GO:0004864	protein phosphatase inhibitor activity	2/1066	53/18639	0.0377358490566038	0.659810966759885	0.814532514617396	0.93798916869003
GO:0008146	sulfotransferase activity	2/1066	53/18639	0.0377358490566038	0.659810966759885	0.814532514617396	0.93798916869003
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/1066	53/18639	0.0377358490566038	0.659810966759885	0.814532514617396	0.93798916869003
GO:0140034	methylation-dependent protein binding	3/1066	76/18639	0.0394736842105263	0.690196998123827	0.817372896037834	0.93798916869003
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/1066	29/18639	0.0344827586206897	0.602930711004723	0.818990542811444	0.93798916869003
GO:0016417	S-acyltransferase activity	1/1066	29/18639	0.0344827586206897	0.602930711004723	0.818990542811444	0.93798916869003
GO:0097472	cyclin-dependent protein kinase activity	1/1066	29/18639	0.0344827586206897	0.602930711004723	0.818990542811444	0.93798916869003
GO:0099604	ligand-gated calcium channel activity	1/1066	29/18639	0.0344827586206897	0.602930711004723	0.818990542811444	0.93798916869003
GO:0106222	lncRNA binding	1/1066	29/18639	0.0344827586206897	0.602930711004723	0.818990542811444	0.93798916869003
GO:0001965	G-protein alpha-subunit binding	1/1066	30/18639	0.0333333333333333	0.582833020637899	0.829358951267274	0.945822123147359
GO:0008187	poly-pyrimidine tract binding	1/1066	30/18639	0.0333333333333333	0.582833020637899	0.829358951267274	0.945822123147359
GO:0022839	monoatomic ion-gated channel activity	1/1066	30/18639	0.0333333333333333	0.582833020637899	0.829358951267274	0.945822123147359
GO:0031624	ubiquitin conjugating enzyme binding	1/1066	30/18639	0.0333333333333333	0.582833020637899	0.829358951267274	0.945822123147359
GO:0008374	O-acyltransferase activity	2/1066	55/18639	0.0363636363636364	0.635817840695889	0.830436150326066	0.946044158501108
GO:0019212	phosphatase inhibitor activity	2/1066	56/18639	0.0357142857142857	0.624463950683463	0.837917834454631	0.948894111623299
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/1066	56/18639	0.0357142857142857	0.624463950683463	0.837917834454631	0.948894111623299
GO:0005164	tumor necrosis factor receptor binding	1/1066	31/18639	0.032258064516129	0.564031955456031	0.839133971845977	0.948894111623299
GO:0005452	solute:inorganic anion antiporter activity	1/1066	31/18639	0.032258064516129	0.564031955456031	0.839133971845977	0.948894111623299
GO:0016411	acylglycerol O-acyltransferase activity	1/1066	31/18639	0.032258064516129	0.564031955456031	0.839133971845977	0.948894111623299
GO:0017147	Wnt-protein binding	1/1066	31/18639	0.032258064516129	0.564031955456031	0.839133971845977	0.948894111623299
GO:0070273	phosphatidylinositol-4-phosphate binding	1/1066	31/18639	0.032258064516129	0.564031955456031	0.839133971845977	0.948894111623299
GO:0015171	amino acid transmembrane transporter activity	4/1066	102/18639	0.0392156862745098	0.685685906632822	0.842057205467056	0.951196337471743
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/1066	57/18639	0.0350877192982456	0.613508442776735	0.845099384510553	0.953281656983208
GO:0005253	monoatomic anion channel activity	4/1066	103/18639	0.0388349514563107	0.679028761908231	0.84745329178481	0.953281656983208
GO:0022884	macromolecule transmembrane transporter activity	1/1066	32/18639	0.03125	0.54640595684803	0.848349534292892	0.953281656983208
GO:0070717	poly-purine tract binding	1/1066	32/18639	0.03125	0.54640595684803	0.848349534292892	0.953281656983208
GO:0140142	nucleocytoplasmic carrier activity	1/1066	32/18639	0.03125	0.54640595684803	0.848349534292892	0.953281656983208
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	10/1066	229/18639	0.0436681222707424	0.763536708259256	0.84976906665896	0.953876899956445
GO:0017116	single-stranded DNA helicase activity	2/1066	58/18639	0.0344827586206897	0.602930711004723	0.851990619933408	0.954480521114916
GO:0015085	calcium ion transmembrane transporter activity	6/1066	147/18639	0.0408163265306122	0.713673086495386	0.852087554763969	0.954480521114916
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/1066	33/18639	0.0303030303030303	0.529848200579908	0.857037629979664	0.959023318724635
GO:0019783	ubiquitin-like protein peptidase activity	5/1066	127/18639	0.0393700787401575	0.688385457446337	0.858320150616607	0.959456935830035
GO:0005254	chloride channel activity	3/1066	83/18639	0.036144578313253	0.63198761273989	0.860740893877994	0.961160664830427
GO:0008376	acetylgalactosaminyltransferase activity	1/1066	34/18639	0.0294117647058824	0.514264429974617	0.865228422543444	0.962162727143747
GO:0015020	glucuronosyltransferase activity	1/1066	34/18639	0.0294117647058824	0.514264429974617	0.865228422543444	0.962162727143747
GO:0015035	protein-disulfide reductase activity	1/1066	34/18639	0.0294117647058824	0.514264429974617	0.865228422543444	0.962162727143747
GO:0019825	oxygen binding	1/1066	34/18639	0.0294117647058824	0.514264429974617	0.865228422543444	0.962162727143747
GO:0051117	ATPase binding	3/1066	84/18639	0.0357142857142857	0.624463950683463	0.866137010333209	0.96217500008
GO:0016798	hydrolase activity, acting on glycosyl bonds	5/1066	130/18639	0.0384615384615385	0.672499639197575	0.871510603466948	0.967142201776986
GO:0000175	3'-5'-RNA exonuclease activity	1/1066	35/18639	0.0285714285714286	0.49957116054677	0.872950352216579	0.967738136066363
GO:0050660	flavin adenine dinucleotide binding	3/1066	86/18639	0.0348837209302326	0.609941533225708	0.876378931502617	0.970535345630997
GO:0000993	RNA polymerase II complex binding	1/1066	36/18639	0.0277777777777778	0.485694183864916	0.88023023420632	0.971788682872477
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1066	36/18639	0.0277777777777778	0.485694183864916	0.88023023420632	0.971788682872477
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/1066	36/18639	0.0277777777777778	0.485694183864916	0.88023023420632	0.971788682872477
GO:0022824	transmitter-gated monoatomic ion channel activity	2/1066	63/18639	0.0317460317460317	0.555079067274189	0.882425096341294	0.972209355886811
GO:0022835	transmitter-gated channel activity	2/1066	63/18639	0.0317460317460317	0.555079067274189	0.882425096341294	0.972209355886811
GO:0043021	ribonucleoprotein complex binding	7/1066	177/18639	0.0395480225988701	0.691496804146659	0.885759856314507	0.974881484567917
GO:0003727	single-stranded RNA binding	3/1066	89/18639	0.0337078651685393	0.589381706263044	0.890438792779486	0.979026036779086
GO:0005109	frizzled binding	1/1066	38/18639	0.0263157894736842	0.460131332082552	0.893563542160232	0.980450478194236
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/1066	38/18639	0.0263157894736842	0.460131332082552	0.893563542160232	0.980450478194236
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/1066	39/18639	0.0256410256410256	0.448333092798384	0.899663282177284	0.986133986190234
GO:0009055	electron transfer activity	4/1066	116/18639	0.0344827586206897	0.602930711004723	0.904483115332151	0.98638572542151
GO:0004532	RNA exonuclease activity	1/1066	40/18639	0.025	0.437124765478424	0.905413762886909	0.98638572542151
GO:0015144	carbohydrate transmembrane transporter activity	1/1066	40/18639	0.025	0.437124765478424	0.905413762886909	0.98638572542151
GO:0071855	neuropeptide receptor binding	1/1066	40/18639	0.025	0.437124765478424	0.905413762886909	0.98638572542151
GO:0071949	FAD binding	1/1066	40/18639	0.025	0.437124765478424	0.905413762886909	0.98638572542151
GO:0140662	ATP-dependent protein folding chaperone	1/1066	40/18639	0.025	0.437124765478424	0.905413762886909	0.98638572542151
GO:0008227	G protein-coupled amine receptor activity	1/1066	41/18639	0.024390243902439	0.426463185832609	0.910834964497885	0.989753993815613
GO:0140318	protein transporter activity	1/1066	41/18639	0.024390243902439	0.426463185832609	0.910834964497885	0.989753993815613
GO:0098960	postsynaptic neurotransmitter receptor activity	2/1066	69/18639	0.0289855072463768	0.506811322293825	0.911275365574637	0.989753993815613
GO:0016782	transferase activity, transferring sulphur-containing groups	2/1066	70/18639	0.0285714285714286	0.49957116054677	0.915385588160862	0.992464907538603
GO:0043175	RNA polymerase core enzyme binding	1/1066	42/18639	0.0238095238095238	0.416309300455642	0.915945725216525	0.992464907538603
GO:0140097	catalytic activity, acting on DNA	14/1066	336/18639	0.0416666666666667	0.728541275797373	0.917789487692335	0.992464907538603
GO:0015399	primary active transmembrane transporter activity	6/1066	166/18639	0.036144578313253	0.63198761273989	0.918388898030367	0.992464907538603
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/1066	43/18639	0.0232558139534884	0.406627688817139	0.920763806461843	0.992464907538603
GO:0015108	chloride transmembrane transporter activity	4/1066	121/18639	0.0330578512396694	0.578016218814445	0.920809539515723	0.992464907538603
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	6/1066	167/18639	0.0359281437125748	0.628203255777376	0.921016985141297	0.992464907538603
GO:0030594	neurotransmitter receptor activity	3/1066	97/18639	0.0309278350515464	0.540772905746504	0.921177782650103	0.992464907538603
GO:0003954	NADH dehydrogenase activity	1/1066	44/18639	0.0227272727272727	0.397386150434931	0.925305954359868	0.995911629592147
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/1066	73/18639	0.0273972602739726	0.479040838880465	0.926668068065156	0.996377300868452
GO:0051539	4 iron, 4 sulfur cluster binding	1/1066	45/18639	0.0222222222222222	0.388555347091932	0.929587957729181	0.998067693903876
GO:0003678	DNA helicase activity	2/1066	74/18639	0.027027027027027	0.472567314030729	0.930102263255571	0.998067693903876
GO:0008509	monoatomic anion transmembrane transporter activity	5/1066	149/18639	0.0335570469798658	0.586744651648891	0.9330305515837	0.999994805861036
GO:0019842	vitamin binding	5/1066	150/18639	0.0333333333333333	0.582833020637899	0.935381467633899	0.999994805861036
GO:0099095	ligand-gated monoatomic anion channel activity	1/1066	47/18639	0.0212765957446809	0.372021077002914	0.93743022455949	0.999994805861036
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/1066	48/18639	0.0208333333333333	0.364270637898687	0.941017755789029	0.999994805861036
GO:0016829	lyase activity	7/1066	200/18639	0.035	0.611974671669794	0.943854512842195	0.999994805861036
GO:0016835	carbon-oxygen lyase activity	2/1066	79/18639	0.0253164556962025	0.442657990357898	0.945106769621964	0.999994805861036
GO:0005262	calcium channel activity	4/1066	131/18639	0.0305343511450382	0.533892843332426	0.946157235270236	0.999994805861036
GO:0004497	monooxygenase activity	3/1066	106/18639	0.0283018867924528	0.494858225069914	0.946196893982626	0.999994805861036
GO:0005179	hormone activity	4/1066	132/18639	0.0303030303030303	0.529848200579908	0.948233563293381	0.999994805861036
GO:0016853	isomerase activity	6/1066	180/18639	0.0333333333333333	0.582833020637899	0.948996491632908	0.999994805861036
GO:0003743	translation initiation factor activity	1/1066	51/18639	0.0196078431372549	0.342842953316411	0.950593640173828	0.999994805861036
GO:0030544	Hsp70 protein binding	1/1066	51/18639	0.0196078431372549	0.342842953316411	0.950593640173828	0.999994805861036
GO:0008168	methyltransferase activity	7/1066	204/18639	0.0343137254901961	0.599975168303719	0.950708493412024	0.999994805861036
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	6/1066	181/18639	0.0331491712707182	0.579612948700673	0.950726661551326	0.999994805861036
GO:0099094	ligand-gated monoatomic cation channel activity	4/1066	136/18639	0.0294117647058824	0.514264429974617	0.955824976403697	0.999994805861036
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/1066	53/18639	0.0188679245283019	0.329905483379943	0.956098085472803	0.999994805861036
GO:0051018	protein kinase A binding	1/1066	53/18639	0.0188679245283019	0.329905483379943	0.956098085472803	0.999994805861036
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/1066	53/18639	0.0188679245283019	0.329905483379943	0.956098085472803	0.999994805861036
GO:0004527	exonuclease activity	2/1066	84/18639	0.0238095238095238	0.416309300455642	0.95701204470543	0.999994805861036
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/1066	54/18639	0.0185185185185185	0.32379612257661	0.958616079709647	0.999994805861036
GO:0015103	inorganic anion transmembrane transporter activity	5/1066	165/18639	0.0303030303030303	0.529848200579908	0.962768110442131	0.999994805861036
GO:0030170	pyridoxal phosphate binding	1/1066	56/18639	0.0178571428571429	0.312231975341731	0.963227453881113	0.999994805861036
GO:0070279	vitamin B6 binding	1/1066	57/18639	0.0175438596491228	0.306754221388368	0.965336883691301	0.999994805861036
GO:0016741	transferase activity, transferring one-carbon groups	7/1066	215/18639	0.0325581395348837	0.569278764343994	0.96585921109231	0.999994805861036
GO:0008408	3'-5' exonuclease activity	1/1066	58/18639	0.0172413793103448	0.301465355502361	0.967325414634422	0.999994805861036
GO:0015459	potassium channel regulator activity	1/1066	59/18639	0.0169491525423729	0.296355773205711	0.969199969717556	0.999994805861036
GO:0036002	pre-mRNA binding	1/1066	59/18639	0.0169491525423729	0.296355773205711	0.969199969717556	0.999994805861036
GO:0015291	secondary active transmembrane transporter activity	10/1066	287/18639	0.0348432055749129	0.609233122618013	0.969436490477649	0.999994805861036
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/1066	60/18639	0.0166666666666667	0.291416510318949	0.970967075868314	0.999994805861036
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1066	60/18639	0.0166666666666667	0.291416510318949	0.970967075868314	0.999994805861036
GO:0003697	single-stranded DNA binding	3/1066	121/18639	0.0247933884297521	0.433512164110834	0.972171071739787	0.999994805861036
GO:0004540	RNA nuclease activity	3/1066	121/18639	0.0247933884297521	0.433512164110834	0.972171071739787	0.999994805861036
GO:0016836	hydro-lyase activity	1/1066	61/18639	0.0163934426229508	0.286639190477655	0.972632886575261	0.999994805861036
GO:1901682	sulfur compound transmembrane transporter activity	1/1066	63/18639	0.0158730158730159	0.277539533637095	0.975683495282009	0.999994805861036
GO:0004519	endonuclease activity	3/1066	127/18639	0.0236220472440945	0.413031274467802	0.978769051125965	0.999994805861036
GO:0005506	iron ion binding	4/1066	154/18639	0.025974025974026	0.454155600497064	0.978856250774758	0.999994805861036
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/1066	68/18639	0.0147058823529412	0.257132214987308	0.981905081475599	0.999994805861036
GO:0140223	general transcription initiation factor activity	1/1066	68/18639	0.0147058823529412	0.257132214987308	0.981905081475599	0.999994805861036
GO:0004518	nuclease activity	6/1066	209/18639	0.0287081339712919	0.501961453180965	0.982074874997283	0.999994805861036
GO:0015276	ligand-gated monoatomic ion channel activity	5/1066	186/18639	0.0268817204301075	0.470026629546692	0.983514838928836	0.999994805861036
GO:0022834	ligand-gated channel activity	5/1066	188/18639	0.0265957446808511	0.465026346253643	0.98478081110569	0.999994805861036
GO:0004521	RNA endonuclease activity	1/1066	73/18639	0.0136986301369863	0.239520419440232	0.986535925253184	0.999994805861036
GO:0031491	nucleosome binding	1/1066	74/18639	0.0135135135135135	0.236283657015364	0.987308989116165	0.999994805861036
GO:0051536	iron-sulfur cluster binding	1/1066	76/18639	0.0131578947368421	0.230065666041276	0.988724615863709	0.999994805861036
GO:0022804	active transmembrane transporter activity	16/1066	457/18639	0.0350109409190372	0.612165973536524	0.989363368518317	0.999994805861036
GO:0051540	metal cluster binding	1/1066	77/18639	0.012987012987013	0.227077800248532	0.989372116778932	0.999994805861036
GO:0043022	ribosome binding	2/1066	112/18639	0.0178571428571429	0.312231975341731	0.989510589863959	0.999994805861036
GO:0000049	tRNA binding	1/1066	80/18639	0.0125	0.218562382739212	0.991100112809572	0.999994805861036
GO:0022853	active monoatomic ion transmembrane transporter activity	2/1066	118/18639	0.0169491525423729	0.296355773205711	0.992303702343299	0.999994805861036
GO:0008135	translation factor activity, RNA binding	1/1066	83/18639	0.0120481927710843	0.210662537579963	0.992547372811947	0.999994805861036
GO:0180051	translation factor activity	1/1066	84/18639	0.0119047619047619	0.208154650227821	0.992975509295158	0.999994805861036
GO:0005267	potassium channel activity	2/1066	124/18639	0.0161290322580645	0.282015977728016	0.994364972408861	0.999994805861036
GO:0015079	potassium ion transmembrane transporter activity	3/1066	160/18639	0.01875	0.327843574108818	0.995469472655403	0.999994805861036
GO:0052689	carboxylic ester hydrolase activity	1/1066	92/18639	0.0108695652173913	0.190054245860184	0.995624708049102	0.999994805861036
GO:0005249	voltage-gated potassium channel activity	1/1066	98/18639	0.0102040816326531	0.178418271623847	0.996932806186408	0.999994805861036
GO:0003730	mRNA 3'-UTR binding	6/1066	262/18639	0.0229007633587786	0.40041963249932	0.997820122076936	0.999994805861036
GO:0015293	symporter activity	2/1066	146/18639	0.0136986301369863	0.239520419440232	0.998231034886281	0.999994805861036
GO:0015294	solute:monoatomic cation symporter activity	1/1066	116/18639	0.00862068965517241	0.150732677751181	0.998944070287362	0.999994805861036
GO:0005261	monoatomic cation channel activity	8/1066	341/18639	0.0234604105571848	0.410205058513477	0.999219215905528	0.999994805861036
GO:0005216	monoatomic ion channel activity	12/1066	448/18639	0.0267857142857143	0.468347963012597	0.999324553150166	0.999994805861036
GO:0046873	metal ion transmembrane transporter activity	12/1066	450/18639	0.0266666666666667	0.466266416510319	0.999371874304751	0.999994805861036
GO:0016874	ligase activity	2/1066	167/18639	0.0119760479041916	0.209401085259125	0.999425561214001	0.999994805861036
GO:0003735	structural constituent of ribosome	2/1066	175/18639	0.0114285714285714	0.199828464218708	0.999627251320593	0.999994805861036
GO:0140098	catalytic activity, acting on RNA	9/1066	387/18639	0.0232558139534884	0.406627688817139	0.999639672229067	0.999994805861036
GO:0140101	catalytic activity, acting on a tRNA	1/1066	139/18639	0.00719424460431655	0.125791299418252	0.9997300936886	0.999994805861036
GO:0015078	proton transmembrane transporter activity	2/1066	185/18639	0.0108108108108108	0.189026925612291	0.999783507735914	0.999994805861036
GO:0022843	voltage-gated monoatomic cation channel activity	1/1066	143/18639	0.00699300699300699	0.122272661672286	0.999787134303785	0.999994805861036
GO:0015081	sodium ion transmembrane transporter activity	1/1066	164/18639	0.00609756097560976	0.106615796458152	0.999938847409471	0.999994805861036
GO:0022836	gated channel activity	5/1066	318/18639	0.0157232704402516	0.274921236149952	0.999953188252101	0.999994805861036
GO:0005244	voltage-gated monoatomic ion channel activity	1/1066	173/18639	0.00578034682080925	0.101069309937208	0.999964184796084	0.999994805861036
GO:0022832	voltage-gated channel activity	1/1066	175/18639	0.00571428571428571	0.0999142321093541	0.999968200607637	0.999994805861036
GO:0045182	translation regulator activity	5/1066	356/18639	0.0140449438202247	0.245575710942935	0.99999258458814	0.999994805861036
GO:0030371	translation repressor activity	4/1066	329/18639	0.0121580547112462	0.212583472573094	0.999994805861036	0.999994805861036