ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 22/585 168/18639 0.130952380952381 4.17234432234432 1.52081470223338e-08 1.28660923808944e-05 GO:0008083 growth factor activity 19/585 162/18639 0.117283950617284 3.73684710351377 8.26194805068702e-07 0.000331574040839071 GO:0023026 MHC class II protein complex binding 8/585 27/18639 0.296296296296296 9.44045584045584 1.17579447106053e-06 0.000331574040839071 GO:0008201 heparin binding 19/585 172/18639 0.11046511627907 3.5195885509839 2.05910103902295e-06 0.000435499869753353 GO:0003779 actin binding 33/585 443/18639 0.0744920993227991 2.37343288765411 4.41038490000728e-06 0.000746237125081232 GO:0005539 glycosaminoglycan binding 22/585 242/18639 0.0909090909090909 2.8965034965035 8.44420882807276e-06 0.0010843106696697 GO:0042605 peptide antigen binding 9/585 45/18639 0.2 6.37230769230769 8.97183769230249e-06 0.0010843106696697 GO:0019955 cytokine binding 16/585 144/18639 0.111111111111111 3.54017094017094 1.21136166593461e-05 0.00128101496172585 GO:0023023 MHC protein complex binding 8/585 37/18639 0.216216216216216 6.88898128898129 1.55006348396483e-05 0.00145705967492694 GO:0005125 cytokine activity 20/585 234/18639 0.0854700854700855 2.72320841551611 5.19649695410302e-05 0.00439623642317115 GO:1901681 sulfur compound binding 22/585 275/18639 0.08 2.54892307692308 6.06311120971081e-05 0.00466308371219577 GO:0042974 nuclear retinoic acid receptor binding 6/585 25/18639 0.24 7.64676923076923 9.9114298613473e-05 0.00685473240431489 GO:0016922 nuclear receptor binding 14/585 137/18639 0.102189781021898 3.25592363840539 0.000105332767442191 0.00685473240431489 GO:0050681 nuclear androgen receptor binding 6/585 26/18639 0.230769230769231 7.35266272189349 0.000125452677594282 0.00758092608891162 GO:0032395 MHC class II receptor activity 4/585 10/18639 0.4 12.7446153846154 0.000173453206120701 0.00978276082520753 GO:0050840 extracellular matrix binding 9/585 67/18639 0.134328358208955 4.27990815154994 0.000234541765200981 0.0124013958350019 GO:0030414 peptidase inhibitor activity 15/585 169/18639 0.0887573964497041 2.82794720072827 0.000291757462775805 0.0133763174288455 GO:0061134 peptidase regulator activity 18/585 226/18639 0.079646017699115 2.53764465622873 0.000292405437471109 0.0133763174288455 GO:0008307 structural constituent of muscle 7/585 42/18639 0.166666666666667 5.31025641025641 0.000300413748401968 0.0133763174288455 GO:0019838 growth factor binding 13/585 136/18639 0.0955882352941176 3.04558823529412 0.000356687739105832 0.0150878913641767 GO:0035259 nuclear glucocorticoid receptor binding 4/585 12/18639 0.333333333333333 10.6205128205128 0.000388847026719381 0.0156287188241664 GO:0005518 collagen binding 9/585 72/18639 0.125 3.98269230769231 0.000406420584079977 0.0156287188241664 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/585 22/18639 0.227272727272727 7.24125874125874 0.000505943081942529 0.0183886455986186 GO:0031994 insulin-like growth factor I binding 4/585 13/18639 0.307692307692308 9.80355029585799 0.000547775485529847 0.0183886455986186 GO:0004866 endopeptidase inhibitor activity 14/585 161/18639 0.0869565217391304 2.77056856187291 0.000565135680335795 0.0183886455986186 GO:0005178 integrin binding 14/585 161/18639 0.0869565217391304 2.77056856187291 0.000565135680335795 0.0183886455986186 GO:0061135 endopeptidase regulator activity 15/585 184/18639 0.0815217391304348 2.59740802675585 0.000717552936207279 0.021819150964417 GO:0005161 platelet-derived growth factor receptor binding 4/585 14/18639 0.285714285714286 9.1032967032967 0.000747937799016658 0.021819150964417 GO:0008191 metalloendopeptidase inhibitor activity 4/585 14/18639 0.285714285714286 9.1032967032967 0.000747937799016658 0.021819150964417 GO:0043394 proteoglycan binding 6/585 37/18639 0.162162162162162 5.16673596673597 0.000945299858287566 0.0260290048795272 GO:0051015 actin filament binding 16/585 209/18639 0.076555023923445 2.43916083916084 0.000953781502677712 0.0260290048795272 GO:0043548 phosphatidylinositol 3-kinase binding 5/585 26/18639 0.192307692307692 6.12721893491124 0.001139380796645 0.0292095804230809 GO:0070412 R-SMAD binding 5/585 26/18639 0.192307692307692 6.12721893491124 0.001139380796645 0.0292095804230809 GO:0140375 immune receptor activity 13/585 156/18639 0.0833333333333333 2.65512820512821 0.00130136148831386 0.0323809358562803 GO:0046966 nuclear thyroid hormone receptor binding 5/585 28/18639 0.178571428571429 5.68956043956044 0.00161655596038308 0.0377271125609876 GO:0030169 low-density lipoprotein particle binding 4/585 17/18639 0.235294117647059 7.49683257918552 0.00165000374084698 0.0377271125609876 GO:0046965 nuclear retinoid X receptor binding 4/585 17/18639 0.235294117647059 7.49683257918552 0.00165000374084698 0.0377271125609876 GO:0001968 fibronectin binding 5/585 30/18639 0.166666666666667 5.31025641025641 0.00222611121728183 0.0495602655215901 GO:0042277 peptide binding 17/585 249/18639 0.0682730923694779 2.17528575841829 0.00232202163628376 0.050370007802463 GO:0005520 insulin-like growth factor binding 4/585 19/18639 0.210526315789474 6.70769230769231 0.00255664332994509 0.0540730064283386 GO:0042975 peroxisome proliferator activated receptor binding 3/585 10/18639 0.3 9.55846153846154 0.00312976317350266 0.0645799913361768 GO:0140297 DNA-binding transcription factor binding 27/585 488/18639 0.055327868852459 1.76283102143758 0.00331203573859961 0.0667138627346493 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 21/585 349/18639 0.0601719197707736 1.91716993608111 0.00352211252836923 0.0692955162558226 GO:0042608 T cell receptor binding 3/585 11/18639 0.272727272727273 8.68951048951049 0.00420374445231544 0.0808265410604286 GO:0070851 growth factor receptor binding 11/585 139/18639 0.079136690647482 2.52141671278362 0.00443656878069371 0.0834074930770418 GO:0016409 palmitoyltransferase activity 5/585 36/18639 0.138888888888889 4.42521367521368 0.00504707454156193 0.0928222839600303 GO:0050431 transforming growth factor beta binding 4/585 24/18639 0.166666666666667 5.31025641025641 0.00619182502064872 0.111157828298234 GO:0005126 cytokine receptor binding 17/585 275/18639 0.0618181818181818 1.96962237762238 0.00630682713748845 0.111157828298234 GO:0019706 protein-cysteine S-palmitoyltransferase activity 4/585 25/18639 0.16 5.09784615384615 0.00719133557317142 0.12167739789806 GO:0019707 protein-cysteine S-acyltransferase activity 4/585 25/18639 0.16 5.09784615384615 0.00719133557317142 0.12167739789806 GO:0005160 transforming growth factor beta receptor binding 4/585 26/18639 0.153846153846154 4.901775147929 0.00829169098708531 0.134899434136042 GO:0030247 polysaccharide binding 4/585 26/18639 0.153846153846154 4.901775147929 0.00829169098708531 0.134899434136042 GO:0005044 scavenger receptor activity 4/585 27/18639 0.148148148148148 4.72022792022792 0.00949674362541448 0.149129784205821 GO:0045296 cadherin binding 19/585 334/18639 0.0568862275449102 1.81248272685398 0.00951892239611624 0.149129784205821 GO:0098631 cell adhesion mediator activity 7/585 76/18639 0.0921052631578947 2.93461538461538 0.00976737063032203 0.150239919150044 GO:0005523 tropomyosin binding 3/585 15/18639 0.2 6.37230769230769 0.0105589721794814 0.156153407201138 GO:0004896 cytokine receptor activity 8/585 96/18639 0.0833333333333333 2.65512820512821 0.0106231747766344 0.156153407201138 GO:0002020 protease binding 10/585 136/18639 0.0735294117647059 2.34276018099548 0.0107055527395579 0.156153407201138 GO:0046332 SMAD binding 7/585 79/18639 0.0886075949367089 2.82317429406037 0.0119583453521559 0.167840176576306 GO:0016417 S-acyltransferase activity 4/585 29/18639 0.137931034482759 4.3946949602122 0.0122351557675748 0.167840176576306 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/585 16/18639 0.1875 5.97403846153846 0.0126971291972619 0.167840176576306 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/585 16/18639 0.1875 5.97403846153846 0.0126971291972619 0.167840176576306 GO:0019841 retinol binding 3/585 16/18639 0.1875 5.97403846153846 0.0126971291972619 0.167840176576306 GO:0070411 I-SMAD binding 3/585 16/18639 0.1875 5.97403846153846 0.0126971291972619 0.167840176576306 GO:0001965 G-protein alpha-subunit binding 4/585 30/18639 0.133333333333333 4.24820512820513 0.0137750087753122 0.176570567029002 GO:0051721 protein phosphatase 2A binding 4/585 30/18639 0.133333333333333 4.24820512820513 0.0137750087753122 0.176570567029002 GO:0071813 lipoprotein particle binding 4/585 32/18639 0.125 3.98269230769231 0.0172103619962532 0.214117150718091 GO:0071814 protein-lipid complex binding 4/585 32/18639 0.125 3.98269230769231 0.0172103619962532 0.214117150718091 GO:0030228 lipoprotein particle receptor activity 3/585 18/18639 0.166666666666667 5.31025641025641 0.0176633948958318 0.215915827645971 GO:0035091 phosphatidylinositol binding 16/585 284/18639 0.0563380281690141 1.79501625135428 0.0178653758099503 0.215915827645971 GO:0015245 fatty acid transmembrane transporter activity 3/585 19/18639 0.157894736842105 5.03076923076923 0.0204959108144355 0.240826952069617 GO:0016918 retinal binding 3/585 19/18639 0.157894736842105 5.03076923076923 0.0204959108144355 0.240826952069617 GO:0003823 antigen binding 11/585 174/18639 0.0632183908045977 2.01423519009726 0.0216419092494341 0.250808975685223 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 3/585 20/18639 0.15 4.77923076923077 0.0235627128636417 0.265787401101878 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/585 20/18639 0.15 4.77923076923077 0.0235627128636417 0.265787401101878 GO:0005543 phospholipid binding 24/585 497/18639 0.0482897384305835 1.53858535830367 0.025001880503644 0.278310406658984 GO:0036122 BMP binding 3/585 21/18639 0.142857142857143 4.55164835164835 0.0268637559177222 0.287680221599911 GO:0051010 microtubule plus-end binding 3/585 21/18639 0.142857142857143 4.55164835164835 0.0268637559177222 0.287680221599911 GO:0061891 calcium ion sensor activity 3/585 21/18639 0.142857142857143 4.55164835164835 0.0268637559177222 0.287680221599911 GO:0001217 DNA-binding transcription repressor activity 15/585 278/18639 0.0539568345323741 1.7191477587161 0.0298993321117329 0.312463743302748 GO:0140784 metal ion sensor activity 3/585 22/18639 0.136363636363636 4.34475524475524 0.030398224154435 0.312463743302748 GO:0005109 frizzled binding 4/585 38/18639 0.105263157894737 3.35384615384615 0.030518219184365 0.312463743302748 GO:0005516 calmodulin binding 12/585 207/18639 0.0579710144927536 1.84704570791527 0.0306554263523973 0.312463743302748 GO:0017022 myosin binding 6/585 76/18639 0.0789473684210526 2.51538461538462 0.0320415686107667 0.322704369579864 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/585 23/18639 0.130434782608696 4.15585284280936 0.0341645961861281 0.332221245672004 GO:0005158 insulin receptor binding 3/585 23/18639 0.130434782608696 4.15585284280936 0.0341645961861281 0.332221245672004 GO:0140103 catalytic activity, acting on a glycoprotein 3/585 23/18639 0.130434782608696 4.15585284280936 0.0341645961861281 0.332221245672004 GO:0030331 nuclear estrogen receptor binding 4/585 40/18639 0.1 3.18615384615385 0.0359945216124333 0.340650775567411 GO:0001786 phosphatidylserine binding 5/585 59/18639 0.0847457627118644 2.70013037809648 0.0373899095300012 0.340650775567411 GO:0005131 growth hormone receptor binding 2/585 10/18639 0.2 6.37230769230769 0.0374474256829423 0.340650775567411 GO:0008239 dipeptidyl-peptidase activity 2/585 10/18639 0.2 6.37230769230769 0.0374474256829423 0.340650775567411 GO:0030957 Tat protein binding 2/585 10/18639 0.2 6.37230769230769 0.0374474256829423 0.340650775567411 GO:0035374 chondroitin sulfate binding 2/585 10/18639 0.2 6.37230769230769 0.0374474256829423 0.340650775567411 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/585 24/18639 0.125 3.98269230769231 0.0381607063526251 0.343446357173626 GO:0004857 enzyme inhibitor activity 20/585 416/18639 0.0480769230769231 1.53180473372781 0.0398131401466487 0.354546490148051 GO:0048487 beta-tubulin binding 4/585 42/18639 0.0952380952380952 3.03443223443223 0.0420012840091798 0.368255671836185 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 14/585 268/18639 0.0522388059701493 1.66440872560276 0.0440482843766467 0.368255671836185 GO:0002162 dystroglycan binding 2/585 11/18639 0.181818181818182 5.79300699300699 0.0448349104008594 0.368255671836185 GO:0008172 S-methyltransferase activity 2/585 11/18639 0.181818181818182 5.79300699300699 0.0448349104008594 0.368255671836185 GO:0043522 leucine zipper domain binding 2/585 11/18639 0.181818181818182 5.79300699300699 0.0448349104008594 0.368255671836185 GO:0050998 nitric-oxide synthase binding 2/585 11/18639 0.181818181818182 5.79300699300699 0.0448349104008594 0.368255671836185 GO:0070697 activin receptor binding 2/585 11/18639 0.181818181818182 5.79300699300699 0.0448349104008594 0.368255671836185 GO:0097493 structural molecule activity conferring elasticity 2/585 11/18639 0.181818181818182 5.79300699300699 0.0448349104008594 0.368255671836185 GO:0019842 vitamin binding 9/585 150/18639 0.06 1.91169230769231 0.0471615765493677 0.383641286161203 GO:0008013 beta-catenin binding 7/585 106/18639 0.0660377358490566 2.10406386066763 0.0493889102290409 0.397933505273987 GO:0005104 fibroblast growth factor receptor binding 3/585 27/18639 0.111111111111111 3.54017094017094 0.0514973314895509 0.401024655842778 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/585 27/18639 0.111111111111111 3.54017094017094 0.0514973314895509 0.401024655842778 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/585 12/18639 0.166666666666667 5.31025641025641 0.0527068170955284 0.401024655842778 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/585 12/18639 0.166666666666667 5.31025641025641 0.0527068170955284 0.401024655842778 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/585 12/18639 0.166666666666667 5.31025641025641 0.0527068170955284 0.401024655842778 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/585 12/18639 0.166666666666667 5.31025641025641 0.0527068170955284 0.401024655842778 GO:0038024 cargo receptor activity 5/585 65/18639 0.0769230769230769 2.4508875739645 0.0530907345796586 0.401024655842778 GO:0005319 lipid transporter activity 10/585 178/18639 0.0561797752808989 1.78997407087295 0.0545538252148196 0.408429523289711 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/585 28/18639 0.107142857142857 3.41373626373626 0.0563797982799466 0.418397450393288 GO:0003714 transcription corepressor activity 11/585 204/18639 0.053921568627451 1.71802413273002 0.0575084983568104 0.419736870778505 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 12/585 229/18639 0.0524017467248908 1.66960026872691 0.0580831736582502 0.419736870778505 GO:0140359 ABC-type transporter activity 4/585 47/18639 0.0851063829787234 2.71162029459902 0.0593357871666755 0.419736870778505 GO:0005172 vascular endothelial growth factor receptor binding 2/585 13/18639 0.153846153846154 4.901775147929 0.0610255734110592 0.419736870778505 GO:0008035 high-density lipoprotein particle binding 2/585 13/18639 0.153846153846154 4.901775147929 0.0610255734110592 0.419736870778505 GO:0017154 semaphorin receptor activity 2/585 13/18639 0.153846153846154 4.901775147929 0.0610255734110592 0.419736870778505 GO:0035325 Toll-like receptor binding 2/585 13/18639 0.153846153846154 4.901775147929 0.0610255734110592 0.419736870778505 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/585 13/18639 0.153846153846154 4.901775147929 0.0610255734110592 0.419736870778505 GO:0140333 glycerophospholipid flippase activity 2/585 13/18639 0.153846153846154 4.901775147929 0.0610255734110592 0.419736870778505 GO:0032266 phosphatidylinositol-3-phosphate binding 4/585 48/18639 0.0833333333333333 2.65512820512821 0.0631954891268915 0.427707070410802 GO:0038187 pattern recognition receptor activity 4/585 48/18639 0.0833333333333333 2.65512820512821 0.0631954891268915 0.427707070410802 GO:0072341 modified amino acid binding 6/585 91/18639 0.0659340659340659 2.10076077768385 0.0665211751511779 0.440064527494755 GO:0033612 receptor serine/threonine kinase binding 3/585 30/18639 0.1 3.18615384615385 0.0667732333333298 0.440064527494755 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/585 30/18639 0.1 3.18615384615385 0.0667732333333298 0.440064527494755 GO:1901981 phosphatidylinositol phosphate binding 10/585 185/18639 0.0540540540540541 1.72224532224532 0.067102037880406 0.440064527494755 GO:0005545 1-phosphatidylinositol binding 2/585 14/18639 0.142857142857143 4.55164835164835 0.069755481257683 0.447069220787878 GO:0008559 ABC-type xenobiotic transporter activity 2/585 14/18639 0.142857142857143 4.55164835164835 0.069755481257683 0.447069220787878 GO:0032036 myosin heavy chain binding 2/585 14/18639 0.142857142857143 4.55164835164835 0.069755481257683 0.447069220787878 GO:0140299 molecular sensor activity 5/585 71/18639 0.0704225352112676 2.24377031419285 0.072090833381226 0.458562744665543 GO:0019902 phosphatase binding 10/585 190/18639 0.0526315789473684 1.67692307692308 0.0771077091629915 0.479984104168409 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/585 32/18639 0.09375 2.98701923076923 0.0779702627874083 0.479984104168409 GO:0042910 xenobiotic transmembrane transporter activity 3/585 32/18639 0.09375 2.98701923076923 0.0779702627874083 0.479984104168409 GO:0005041 low-density lipoprotein particle receptor activity 2/585 15/18639 0.133333333333333 4.24820512820513 0.0788626365004832 0.479984104168409 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/585 15/18639 0.133333333333333 4.24820512820513 0.0788626365004832 0.479984104168409 GO:0031005 filamin binding 2/585 15/18639 0.133333333333333 4.24820512820513 0.0788626365004832 0.479984104168409 GO:0030296 protein tyrosine kinase activator activity 3/585 33/18639 0.0909090909090909 2.8965034965035 0.0838562047004548 0.506731065547034 GO:0008142 oxysterol binding 2/585 16/18639 0.125 3.98269230769231 0.0883148518295149 0.522478074459928 GO:0030275 LRR domain binding 2/585 16/18639 0.125 3.98269230769231 0.0883148518295149 0.522478074459928 GO:0140327 flippase activity 2/585 16/18639 0.125 3.98269230769231 0.0883148518295149 0.522478074459928 GO:0140463 chromatin-protein adaptor activity 4/585 54/18639 0.0740740740740741 2.36011396011396 0.0890038959264689 0.522897888568005 GO:0051427 hormone receptor binding 3/585 34/18639 0.0882352941176471 2.81131221719457 0.0899258928730955 0.524671071521647 GO:0098632 cell-cell adhesion mediator activity 4/585 55/18639 0.0727272727272727 2.3172027972028 0.0937312642881797 0.538028955374778 GO:0016229 steroid dehydrogenase activity 3/585 35/18639 0.0857142857142857 2.73098901098901 0.0961731981300949 0.538028955374778 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/585 17/18639 0.117647058823529 3.74841628959276 0.098081582691251 0.538028955374778 GO:0008429 phosphatidylethanolamine binding 2/585 17/18639 0.117647058823529 3.74841628959276 0.098081582691251 0.538028955374778 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/585 17/18639 0.117647058823529 3.74841628959276 0.098081582691251 0.538028955374778 GO:0038191 neuropilin binding 2/585 17/18639 0.117647058823529 3.74841628959276 0.098081582691251 0.538028955374778 GO:0045125 bioactive lipid receptor activity 2/585 17/18639 0.117647058823529 3.74841628959276 0.098081582691251 0.538028955374778 GO:0019199 transmembrane receptor protein kinase activity 5/585 78/18639 0.0641025641025641 2.04240631163708 0.0983453972104406 0.538028955374778 GO:0030170 pyridoxal phosphate binding 4/585 56/18639 0.0714285714285714 2.27582417582418 0.0985750450154734 0.538028955374778 GO:0170055 lipid transmembrane transporter activity 4/585 56/18639 0.0714285714285714 2.27582417582418 0.0985750450154734 0.538028955374778 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/585 36/18639 0.0833333333333333 2.65512820512821 0.10259184504369 0.556363467352321 GO:0070279 vitamin B6 binding 4/585 57/18639 0.0701754385964912 2.23589743589744 0.103532988395001 0.557891134918288 GO:0030246 carbohydrate binding 13/585 280/18639 0.0464285714285714 1.47928571428571 0.104240014715348 0.558145901577115 GO:0031267 small GTPase binding 13/585 283/18639 0.0459363957597173 1.46360424028269 0.110667642442103 0.588835380541001 GO:0005501 retinoid binding 3/585 38/18639 0.0789473684210526 2.51538461538462 0.115917485301349 0.608462045922126 GO:0019840 isoprenoid binding 3/585 38/18639 0.0789473684210526 2.51538461538462 0.115917485301349 0.608462045922126 GO:0000149 SNARE binding 6/585 106/18639 0.0566037735849057 1.80348330914369 0.116514008793599 0.608462045922126 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/585 19/18639 0.105263157894737 3.35384615384615 0.118444202677589 0.609807592038759 GO:0043395 heparan sulfate proteoglycan binding 2/585 19/18639 0.105263157894737 3.35384615384615 0.118444202677589 0.609807592038759 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/585 60/18639 0.0666666666666667 2.12410256410256 0.119067796661289 0.609807592038759 GO:0001540 amyloid-beta binding 5/585 83/18639 0.0602409638554217 1.91936978683967 0.119654917586801 0.609807592038759 GO:0051020 GTPase binding 14/585 315/18639 0.0444444444444444 1.41606837606838 0.122017951180616 0.618126866459888 GO:0015026 coreceptor activity 4/585 61/18639 0.0655737704918033 2.08928121059269 0.124457942551596 0.62673463927768 GO:0001972 retinoic acid binding 2/585 20/18639 0.1 3.18615384615385 0.128986590434694 0.645696186436399 GO:0004222 metalloendopeptidase activity 6/585 110/18639 0.0545454545454545 1.7379020979021 0.132339510437281 0.658583681352588 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/585 86/18639 0.0581395348837209 1.85241502683363 0.133395105467175 0.659954732311289 GO:1902936 phosphatidylinositol bisphosphate binding 6/585 111/18639 0.0540540540540541 1.72224532224532 0.136448654917683 0.666241816238963 GO:0001530 lipopolysaccharide binding 3/585 41/18639 0.0731707317073171 2.33133208255159 0.137028458659078 0.666241816238963 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/585 41/18639 0.0731707317073171 2.33133208255159 0.137028458659078 0.666241816238963 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/585 21/18639 0.0952380952380952 3.03443223443223 0.139736362489113 0.671687287873804 GO:0010314 phosphatidylinositol-5-phosphate binding 2/585 21/18639 0.0952380952380952 3.03443223443223 0.139736362489113 0.671687287873804 GO:0005200 structural constituent of cytoskeleton 6/585 112/18639 0.0535714285714286 1.70686813186813 0.140617159091345 0.672102353623037 GO:0035198 miRNA binding 3/585 42/18639 0.0714285714285714 2.27582417582418 0.144338241324454 0.682179621008316 GO:0042056 chemoattractant activity 3/585 42/18639 0.0714285714285714 2.27582417582418 0.144338241324454 0.682179621008316 GO:0030295 protein kinase activator activity 7/585 139/18639 0.0503597122302158 1.60453790813503 0.147785612865317 0.694592380466988 GO:0003712 transcription coregulator activity 20/585 495/18639 0.0404040404040404 1.28733488733489 0.150245693424018 0.7003679624665 GO:0008093 cytoskeletal anchor activity 2/585 22/18639 0.0909090909090909 2.8965034965035 0.15067017632258 0.7003679624665 GO:0008375 acetylglucosaminyltransferase activity 3/585 43/18639 0.0697674418604651 2.22289803220036 0.151773312650615 0.701640560122513 GO:0031625 ubiquitin protein ligase binding 13/585 302/18639 0.043046357615894 1.37152317880795 0.156608683254311 0.716513037680839 GO:0001046 core promoter sequence-specific DNA binding 3/585 44/18639 0.0681818181818182 2.17237762237762 0.159327023544888 0.716513037680839 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/585 44/18639 0.0681818181818182 2.17237762237762 0.159327023544888 0.716513037680839 GO:0043014 alpha-tubulin binding 3/585 44/18639 0.0681818181818182 2.17237762237762 0.159327023544888 0.716513037680839 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/585 23/18639 0.0869565217391304 2.77056856187291 0.161765945859386 0.716513037680839 GO:0042171 lysophosphatidic acid acyltransferase activity 2/585 23/18639 0.0869565217391304 2.77056856187291 0.161765945859386 0.716513037680839 GO:0071617 lysophospholipid acyltransferase activity 2/585 23/18639 0.0869565217391304 2.77056856187291 0.161765945859386 0.716513037680839 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/585 23/18639 0.0869565217391304 2.77056856187291 0.161765945859386 0.716513037680839 GO:0043178 alcohol binding 5/585 92/18639 0.0543478260869565 1.73160535117057 0.162843615659651 0.717529681500339 GO:1990841 promoter-specific chromatin binding 4/585 68/18639 0.0588235294117647 1.87420814479638 0.16487267411913 0.722706125931522 GO:0140303 intramembrane lipid transporter activity 3/585 45/18639 0.0666666666666667 2.12410256410256 0.166992755181524 0.728226138575099 GO:0070840 dynein complex binding 2/585 24/18639 0.0833333333333333 2.65512820512821 0.173002785814546 0.747570774935376 GO:0042562 hormone binding 5/585 94/18639 0.0531914893617021 1.69476268412439 0.173196066060678 0.747570774935376 GO:0061749 forked DNA-dependent helicase activity 3/585 47/18639 0.0638297872340425 2.03371522094926 0.182634032603679 0.764555738783242 GO:0140938 histone H3 methyltransferase activity 3/585 47/18639 0.0638297872340425 2.03371522094926 0.182634032603679 0.764555738783242 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/585 47/18639 0.0638297872340425 2.03371522094926 0.182634032603679 0.764555738783242 GO:0003713 transcription coactivator activity 11/585 256/18639 0.04296875 1.36905048076923 0.183024799655409 0.764555738783242 GO:0016407 acetyltransferase activity 5/585 96/18639 0.0520833333333333 1.65945512820513 0.18379386413445 0.764555738783242 GO:0019209 kinase activator activity 7/585 148/18639 0.0472972972972973 1.50696465696466 0.184303618230902 0.764555738783242 GO:0001848 complement binding 2/585 25/18639 0.08 2.54892307692308 0.184360958288158 0.764555738783242 GO:0015271 outward rectifier potassium channel activity 2/585 25/18639 0.08 2.54892307692308 0.184360958288158 0.764555738783242 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/585 122/18639 0.0491803278688525 1.56696090794451 0.185348439103414 0.764901363324332 GO:0009378 four-way junction helicase activity 3/585 48/18639 0.0625 1.99134615384615 0.190596602168798 0.775215026128861 GO:0036121 double-stranded DNA helicase activity 3/585 48/18639 0.0625 1.99134615384615 0.190596602168798 0.775215026128861 GO:0043138 3'-5' DNA helicase activity 3/585 48/18639 0.0625 1.99134615384615 0.190596602168798 0.775215026128861 GO:0042626 ATPase-coupled transmembrane transporter activity 5/585 98/18639 0.0510204081632653 1.62558869701727 0.194622686348251 0.786785446058821 GO:0008198 ferrous iron binding 2/585 26/18639 0.0769230769230769 2.4508875739645 0.195821821520117 0.786785446058821 GO:0004521 RNA endonuclease activity 4/585 73/18639 0.0547945205479452 1.74583772391992 0.196231358295994 0.786785446058821 GO:0005006 epidermal growth factor receptor activity 3/585 50/18639 0.06 1.91169230769231 0.206773711788308 0.824516499886899 GO:0044389 ubiquitin-like protein ligase binding 13/585 322/18639 0.0403726708074534 1.28633540372671 0.21402766420388 0.824516499886899 GO:0005021 vascular endothelial growth factor receptor activity 3/585 51/18639 0.0588235294117647 1.87420814479638 0.214975752316505 0.824516499886899 GO:0008237 metallopeptidase activity 8/585 184/18639 0.0434782608695652 1.38528428093645 0.22222594463299 0.824516499886899 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/585 52/18639 0.0576923076923077 1.83816568047337 0.223245277783108 0.824516499886899 GO:0008514 organic anion transmembrane transporter activity 11/585 269/18639 0.0408921933085502 1.30288818987704 0.226335962577449 0.824516499886899 GO:0004181 metallocarboxypeptidase activity 2/585 29/18639 0.0689655172413793 2.1973474801061 0.230649561653636 0.824516499886899 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/585 29/18639 0.0689655172413793 2.1973474801061 0.230649561653636 0.824516499886899 GO:0043236 laminin binding 2/585 29/18639 0.0689655172413793 2.1973474801061 0.230649561653636 0.824516499886899 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/585 29/18639 0.0689655172413793 2.1973474801061 0.230649561653636 0.824516499886899 GO:0097472 cyclin-dependent protein kinase activity 2/585 29/18639 0.0689655172413793 2.1973474801061 0.230649561653636 0.824516499886899 GO:0005544 calcium-dependent phospholipid binding 3/585 53/18639 0.0566037735849057 1.80348330914369 0.231576289687515 0.824516499886899 GO:0017046 peptide hormone binding 3/585 53/18639 0.0566037735849057 1.80348330914369 0.231576289687515 0.824516499886899 GO:0038064 collagen receptor activity 3/585 53/18639 0.0566037735849057 1.80348330914369 0.231576289687515 0.824516499886899 GO:0005179 hormone activity 6/585 132/18639 0.0454545454545455 1.44825174825175 0.234832708328066 0.824516499886899 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 6/585 132/18639 0.0454545454545455 1.44825174825175 0.234832708328066 0.824516499886899 GO:0033293 monocarboxylic acid binding 4/585 79/18639 0.0506329113924051 1.61324245374878 0.235991337213082 0.824516499886899 GO:0004497 monooxygenase activity 5/585 106/18639 0.0471698113207547 1.50290275761974 0.239951771131742 0.824516499886899 GO:0003925 G protein activity 3/585 54/18639 0.0555555555555556 1.77008547008547 0.239962901085224 0.824516499886899 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/585 30/18639 0.0666666666666667 2.12410256410256 0.242355013676515 0.824516499886899 GO:0008374 O-acyltransferase activity 3/585 55/18639 0.0545454545454545 1.7379020979021 0.248399341669668 0.824516499886899 GO:0016411 acylglycerol O-acyltransferase activity 2/585 31/18639 0.0645161290322581 2.05558312655087 0.254084737234327 0.824516499886899 GO:0070273 phosphatidylinositol-4-phosphate binding 2/585 31/18639 0.0645161290322581 2.05558312655087 0.254084737234327 0.824516499886899 GO:0016504 peptidase activator activity 3/585 57/18639 0.0526315789473684 1.67692307692308 0.265399238559445 0.824516499886899 GO:0008236 serine-type peptidase activity 8/585 194/18639 0.0412371134020619 1.31387787470262 0.265583977210152 0.824516499886899 GO:0043425 bHLH transcription factor binding 2/585 32/18639 0.0625 1.99134615384615 0.265825702197454 0.824516499886899 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0003796 lysozyme activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0005522 profilin binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0008140 cAMP response element binding protein binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0008401 retinoic acid 4-hydroxylase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0015279 store-operated calcium channel activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0032052 bile acid binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0043121 neurotrophin binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0045322 unmethylated CpG binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0047429 nucleoside triphosphate diphosphatase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0050308 sugar-phosphatase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0051378 serotonin binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0070513 death domain binding 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0140940 histone H2A methyltransferase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0140999 histone H3K4 trimethyltransferase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:1990259 histone H2AQ104 methyltransferase activity 1/585 10/18639 0.1 3.18615384615385 0.273100598302937 0.824516499886899 GO:0017116 single-stranded DNA helicase activity 3/585 58/18639 0.0517241379310345 1.64801061007958 0.27395177474684 0.824516499886899 GO:0061980 regulatory RNA binding 3/585 58/18639 0.0517241379310345 1.64801061007958 0.27395177474684 0.824516499886899 GO:0004713 protein tyrosine kinase activity 6/585 140/18639 0.0428571428571429 1.36549450549451 0.277009190760431 0.824516499886899 GO:0071889 14-3-3 protein binding 2/585 33/18639 0.0606060606060606 1.93100233100233 0.277565669777906 0.824516499886899 GO:0140311 protein sequestering activity 2/585 33/18639 0.0606060606060606 1.93100233100233 0.277565669777906 0.824516499886899 GO:0019887 protein kinase regulator activity 10/585 255/18639 0.0392156862745098 1.24947209653092 0.280902128323576 0.824516499886899 GO:0036002 pre-mRNA binding 3/585 59/18639 0.0508474576271186 1.62007822685789 0.282532306061991 0.824516499886899 GO:0017171 serine hydrolase activity 8/585 198/18639 0.0404040404040404 1.28733488733489 0.283589121999767 0.824516499886899 GO:0050660 flavin adenine dinucleotide binding 4/585 86/18639 0.0465116279069767 1.48193202146691 0.284467939246528 0.824516499886899 GO:0020037 heme binding 6/585 142/18639 0.0422535211267606 1.34626218851571 0.287825722377295 0.824516499886899 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/585 34/18639 0.0588235294117647 1.87420814479638 0.289293155834457 0.824516499886899 GO:0030332 cyclin binding 2/585 34/18639 0.0588235294117647 1.87420814479638 0.289293155834457 0.824516499886899 GO:0008081 phosphoric diester hydrolase activity 4/585 87/18639 0.0459770114942529 1.46489832007073 0.291520560148763 0.824516499886899 GO:0019207 kinase regulator activity 11/585 287/18639 0.0383275261324042 1.22117394800322 0.292065153024191 0.824516499886899 GO:0001851 complement component C3b binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0005225 volume-sensitive anion channel activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0008199 ferric iron binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0010854 adenylate cyclase regulator activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0015173 aromatic amino acid transmembrane transporter activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0019107 myristoyltransferase activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0019203 carbohydrate phosphatase activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0019864 IgG binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0034713 type I transforming growth factor beta receptor binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0045294 alpha-catenin binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0047676 arachidonate-CoA ligase activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0048185 activin binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0070990 snRNP binding 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0180030 inositol phosphate kinase activity 1/585 11/18639 0.0909090909090909 2.8965034965035 0.295927167093145 0.824516499886899 GO:0004197 cysteine-type endopeptidase activity 4/585 88/18639 0.0454545454545455 1.44825174825175 0.298596302573122 0.824516499886899 GO:0019903 protein phosphatase binding 6/585 144/18639 0.0416666666666667 1.3275641025641 0.298730093475285 0.824516499886899 GO:0043015 gamma-tubulin binding 2/585 35/18639 0.0571428571428571 1.82065934065934 0.300997395695327 0.824516499886899 GO:0140566 histone reader activity 2/585 35/18639 0.0571428571428571 1.82065934065934 0.300997395695327 0.824516499886899 GO:0008168 methyltransferase activity 8/585 204/18639 0.0392156862745098 1.24947209653092 0.311154228395412 0.824516499886899 GO:0004033 aldo-keto reductase (NADPH) activity 2/585 36/18639 0.0555555555555556 1.77008547008547 0.312668310439541 0.824516499886899 GO:0005484 SNAP receptor activity 2/585 36/18639 0.0555555555555556 1.77008547008547 0.312668310439541 0.824516499886899 GO:0045505 dynein intermediate chain binding 2/585 36/18639 0.0555555555555556 1.77008547008547 0.312668310439541 0.824516499886899 GO:0004252 serine-type endopeptidase activity 7/585 176/18639 0.0397727272727273 1.26722027972028 0.316117742000219 0.824516499886899 GO:0005507 copper ion binding 3/585 63/18639 0.0476190476190476 1.51721611721612 0.317033798763403 0.824516499886899 GO:0000340 RNA 7-methylguanosine cap binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0003995 acyl-CoA dehydrogenase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0008179 adenylate cyclase binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0008504 monoamine transmembrane transporter activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0015132 prostaglandin transmembrane transporter activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0015269 calcium-activated potassium channel activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0016208 AMP binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0016273 arginine N-methyltransferase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0016274 protein-arginine N-methyltransferase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0016801 hydrolase activity, acting on ether bonds 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0016803 ether hydrolase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0016840 carbon-nitrogen lyase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0017166 vinculin binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0031543 peptidyl-proline dioxygenase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0035197 siRNA binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0036009 protein-glutamine N-methyltransferase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0045295 gamma-catenin binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0070410 co-SMAD binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0070679 inositol 1,4,5 trisphosphate binding 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/585 12/18639 0.0833333333333333 2.65512820512821 0.318038108002019 0.824516499886899 GO:0043021 ribonucleoprotein complex binding 7/585 177/18639 0.0395480225988701 1.26006084311169 0.321163187819939 0.824516499886899 GO:0042805 actinin binding 2/585 37/18639 0.0540540540540541 1.72224532224532 0.324296474580296 0.824516499886899 GO:0015631 tubulin binding 14/585 385/18639 0.0363636363636364 1.1586013986014 0.324663634903972 0.824516499886899 GO:0004540 RNA nuclease activity 5/585 121/18639 0.0413223140495868 1.31659249841068 0.330905598234696 0.824516499886899 GO:0016887 ATP hydrolysis activity 15/585 417/18639 0.0359712230215827 1.14609850581074 0.331231868100108 0.824516499886899 GO:0019843 rRNA binding 3/585 65/18639 0.0461538461538462 1.4705325443787 0.334325599280533 0.824516499886899 GO:0004518 nuclease activity 8/585 209/18639 0.0382775119617225 1.21958041958042 0.334530137655846 0.824516499886899 GO:0000146 microfilament motor activity 2/585 38/18639 0.0526315789473684 1.67692307692308 0.335873085095794 0.824516499886899 GO:0043531 ADP binding 2/585 38/18639 0.0526315789473684 1.67692307692308 0.335873085095794 0.824516499886899 GO:0004993 G protein-coupled serotonin receptor activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0019855 calcium channel inhibitor activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0035673 oligopeptide transmembrane transporter activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0045159 myosin II binding 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0046974 histone H3K9 methyltransferase activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0051011 microtubule minus-end binding 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0070700 BMP receptor binding 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0071714 icosanoid transmembrane transporter activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/585 13/18639 0.0769230769230769 2.4508875739645 0.339455819217933 0.824516499886899 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 7/585 181/18639 0.0386740331491713 1.23221419464513 0.341470569962776 0.824516499886899 GO:0046906 tetrapyrrole binding 6/585 152/18639 0.0394736842105263 1.25769230769231 0.343017322627179 0.824516499886899 GO:0004867 serine-type endopeptidase inhibitor activity 4/585 95/18639 0.0421052631578947 1.34153846153846 0.348542733617954 0.824516499886899 GO:0008276 protein methyltransferase activity 4/585 95/18639 0.0421052631578947 1.34153846153846 0.348542733617954 0.824516499886899 GO:0042054 histone methyltransferase activity 3/585 67/18639 0.0447761194029851 1.42663605051665 0.351597383778002 0.824516499886899 GO:0005506 iron ion binding 6/585 154/18639 0.038961038961039 1.24135864135864 0.354205350733962 0.824516499886899 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/585 40/18639 0.05 1.59307692307692 0.358839368687793 0.824516499886899 GO:0004065 arylsulfatase activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0008195 phosphatidate phosphatase activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0019763 immunoglobulin receptor activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0043176 amine binding 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0046030 inositol trisphosphate phosphatase activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0061783 peptidoglycan muralytic activity 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0071933 Arp2/3 complex binding 1/585 14/18639 0.0714285714285714 2.27582417582418 0.360201999061029 0.824516499886899 GO:0005548 phospholipid transporter activity 3/585 68/18639 0.0441176470588235 1.40565610859729 0.360215447300719 0.824516499886899 GO:0032934 sterol binding 3/585 68/18639 0.0441176470588235 1.40565610859729 0.360215447300719 0.824516499886899 GO:0016741 transferase activity, transferring one-carbon groups 8/585 215/18639 0.0372093023255814 1.18554561717352 0.362923649117781 0.824516499886899 GO:0004519 endonuclease activity 5/585 127/18639 0.0393700787401575 1.25439127801333 0.368335226244856 0.824516499886899 GO:0042826 histone deacetylase binding 5/585 127/18639 0.0393700787401575 1.25439127801333 0.368335226244856 0.824516499886899 GO:0016279 protein-lysine N-methyltransferase activity 3/585 69/18639 0.0434782608695652 1.38528428093645 0.368816396842682 0.824516499886899 GO:0008170 N-methyltransferase activity 4/585 98/18639 0.0408163265306122 1.30047095761381 0.370027491481003 0.824516499886899 GO:0008227 G protein-coupled amine receptor activity 2/585 41/18639 0.0487804878048781 1.55422138836773 0.370214287150804 0.824516499886899 GO:0042287 MHC protein binding 2/585 41/18639 0.0487804878048781 1.55422138836773 0.370214287150804 0.824516499886899 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/585 70/18639 0.0428571428571429 1.36549450549451 0.377396483280362 0.824516499886899 GO:0016278 lysine N-methyltransferase activity 3/585 70/18639 0.0428571428571429 1.36549450549451 0.377396483280362 0.824516499886899 GO:0097110 scaffold protein binding 3/585 70/18639 0.0428571428571429 1.36549450549451 0.377396483280362 0.824516499886899 GO:0000774 adenyl-nucleotide exchange factor activity 1/585 15/18639 0.0666666666666667 2.12410256410256 0.380297667815353 0.824516499886899 GO:0004467 long-chain fatty acid-CoA ligase activity 1/585 15/18639 0.0666666666666667 2.12410256410256 0.380297667815353 0.824516499886899 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/585 15/18639 0.0666666666666667 2.12410256410256 0.380297667815353 0.824516499886899 GO:0033130 acetylcholine receptor binding 1/585 15/18639 0.0666666666666667 2.12410256410256 0.380297667815353 0.824516499886899 GO:0051371 muscle alpha-actinin binding 1/585 15/18639 0.0666666666666667 2.12410256410256 0.380297667815353 0.824516499886899 GO:0120283 protein serine/threonine kinase binding 1/585 15/18639 0.0666666666666667 2.12410256410256 0.380297667815353 0.824516499886899 GO:0043130 ubiquitin binding 4/585 100/18639 0.04 1.27446153846154 0.384327928168927 0.824516499886899 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/585 43/18639 0.0465116279069767 1.48193202146691 0.392714663919757 0.824516499886899 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/585 43/18639 0.0465116279069767 1.48193202146691 0.392714663919757 0.824516499886899 GO:0048156 tau protein binding 2/585 43/18639 0.0465116279069767 1.48193202146691 0.392714663919757 0.824516499886899 GO:0031072 heat shock protein binding 5/585 131/18639 0.0381679389312977 1.21608925425719 0.393332191046693 0.824516499886899 GO:0004175 endopeptidase activity 14/585 405/18639 0.0345679012345679 1.10138651471985 0.394328826128618 0.824516499886899 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0004708 MAP kinase kinase activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0005024 transforming growth factor beta receptor activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0005159 insulin-like growth factor receptor binding 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0015562 efflux transmembrane transporter activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0022858 alanine transmembrane transporter activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0140328 floppase activity 1/585 16/18639 0.0625 1.99134615384615 0.399763188881076 0.824516499886899 GO:0043539 protein serine/threonine kinase activator activity 3/585 73/18639 0.0410958904109589 1.30937829293994 0.402976110634333 0.824516499886899 GO:0001223 transcription coactivator binding 2/585 44/18639 0.0454545454545455 1.44825174825175 0.403828361080465 0.824516499886899 GO:0016248 channel inhibitor activity 2/585 44/18639 0.0454545454545455 1.44825174825175 0.403828361080465 0.824516499886899 GO:0030547 signaling receptor inhibitor activity 2/585 44/18639 0.0454545454545455 1.44825174825175 0.403828361080465 0.824516499886899 GO:0003678 DNA helicase activity 3/585 74/18639 0.0405405405405405 1.29168399168399 0.411437961145686 0.824516499886899 GO:0008009 chemokine activity 2/585 45/18639 0.0444444444444444 1.41606837606838 0.414843970657159 0.824516499886899 GO:0046915 transition metal ion transmembrane transporter activity 2/585 45/18639 0.0444444444444444 1.41606837606838 0.414843970657159 0.824516499886899 GO:0141110 transporter inhibitor activity 2/585 45/18639 0.0444444444444444 1.41606837606838 0.414843970657159 0.824516499886899 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0004549 tRNA-specific ribonuclease activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0005092 GDP-dissociation inhibitor activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0008484 sulfuric ester hydrolase activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0008569 minus-end-directed microtubule motor activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0016805 dipeptidase activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0019198 transmembrane receptor protein phosphatase activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0030548 acetylcholine receptor regulator activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0032977 membrane insertase activity 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0045236 CXCR chemokine receptor binding 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0048038 quinone binding 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0070403 NAD+ binding 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:1990226 histone methyltransferase binding 1/585 17/18639 0.0588235294117647 1.87420814479638 0.41861828926794 0.824516499886899 GO:0003725 double-stranded RNA binding 3/585 75/18639 0.04 1.27446153846154 0.419862221157939 0.824516499886899 GO:0044325 transmembrane transporter binding 5/585 136/18639 0.0367647058823529 1.17138009049774 0.424451653845512 0.824516499886899 GO:0004180 carboxypeptidase activity 2/585 46/18639 0.0434782608695652 1.38528428093645 0.425756699694708 0.824516499886899 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/585 46/18639 0.0434782608695652 1.38528428093645 0.425756699694708 0.824516499886899 GO:0030291 protein serine/threonine kinase inhibitor activity 2/585 46/18639 0.0434782608695652 1.38528428093645 0.425756699694708 0.824516499886899 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/585 167/18639 0.0359281437125748 1.14472593274988 0.42715181439214 0.824516499886899 GO:0000287 magnesium ion binding 8/585 230/18639 0.0347826086956522 1.10822742474916 0.434525904013047 0.824516499886899 GO:0005504 fatty acid binding 2/585 47/18639 0.0425531914893617 1.35581014729951 0.43656215156542 0.824516499886899 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0004706 JUN kinase kinase kinase activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0008525 phosphatidylcholine transporter activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0015172 acidic amino acid transmembrane transporter activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0016854 racemase and epimerase activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0034185 apolipoprotein binding 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0035615 clathrin adaptor activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0050811 GABA receptor binding 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0098641 cadherin binding involved in cell-cell adhesion 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0099602 neurotransmitter receptor regulator activity 1/585 18/18639 0.0555555555555556 1.77008547008547 0.436882079450426 0.824516499886899 GO:0005496 steroid binding 4/585 108/18639 0.037037037037037 1.18005698005698 0.440967645579185 0.824516499886899 GO:0140767 enzyme-substrate adaptor activity 5/585 139/18639 0.0359712230215827 1.14609850581074 0.442986383592237 0.824516499886899 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/585 19/18639 0.0526315789473684 1.67692307692308 0.454573072604473 0.824516499886899 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/585 19/18639 0.0526315789473684 1.67692307692308 0.454573072604473 0.824516499886899 GO:0042577 lipid phosphatase activity 1/585 19/18639 0.0526315789473684 1.67692307692308 0.454573072604473 0.824516499886899 GO:0042800 histone H3K4 methyltransferase activity 1/585 19/18639 0.0526315789473684 1.67692307692308 0.454573072604473 0.824516499886899 GO:0099589 serotonin receptor activity 1/585 19/18639 0.0526315789473684 1.67692307692308 0.454573072604473 0.824516499886899 GO:0005004 GPI-linked ephrin receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0005008 hepatocyte growth factor receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0005009 insulin receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0005011 macrophage colony-stimulating factor receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0005020 stem cell factor receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0008288 boss receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0016763 pentosyltransferase activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0036332 placental growth factor receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0038062 protein tyrosine kinase collagen receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0060175 brain-derived neurotrophic factor receptor activity 2/585 49/18639 0.0408163265306122 1.30047095761381 0.457835499307205 0.824516499886899 GO:0106310 protein serine kinase activity 12/585 361/18639 0.0332409972299169 1.05910931174089 0.461068608011273 0.824516499886899 GO:0016757 glycosyltransferase activity 9/585 267/18639 0.0337078651685393 1.07398444252377 0.461527919429047 0.824516499886899 GO:0005007 fibroblast growth factor receptor activity 2/585 50/18639 0.04 1.27446153846154 0.468296407120492 0.824516499886899 GO:0005017 platelet-derived growth factor receptor activity 2/585 50/18639 0.04 1.27446153846154 0.468296407120492 0.824516499886899 GO:0005019 platelet-derived growth factor beta-receptor activity 2/585 50/18639 0.04 1.27446153846154 0.468296407120492 0.824516499886899 GO:0015605 organophosphate ester transmembrane transporter activity 2/585 50/18639 0.04 1.27446153846154 0.468296407120492 0.824516499886899 GO:0043022 ribosome binding 4/585 112/18639 0.0357142857142857 1.13791208791209 0.468730654107973 0.824516499886899 GO:0001618 virus receptor activity 3/585 81/18639 0.037037037037037 1.18005698005698 0.469461779065676 0.824516499886899 GO:0015101 organic cation transmembrane transporter activity 3/585 81/18639 0.037037037037037 1.18005698005698 0.469461779065676 0.824516499886899 GO:0000339 RNA cap binding 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0001614 purinergic nucleotide receptor activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0005326 neurotransmitter transmembrane transporter activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0010851 cyclase regulator activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0016408 C-acyltransferase activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0016502 nucleotide receptor activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0016505 peptidase activator activity involved in apoptotic process 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0031418 L-ascorbic acid binding 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0042288 MHC class I protein binding 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0043024 ribosomal small subunit binding 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0052745 inositol phosphate phosphatase activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0061608 nuclear import signal receptor activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0140939 histone H4 methyltransferase activity 1/585 20/18639 0.05 1.59307692307692 0.471709203244987 0.824516499886899 GO:0140272 exogenous protein binding 3/585 82/18639 0.0365853658536585 1.1656660412758 0.47754717551358 0.826105646726235 GO:0003743 translation initiation factor activity 2/585 51/18639 0.0392156862745098 1.24947209653092 0.47863602568392 0.826105646726235 GO:0005010 insulin-like growth factor receptor activity 2/585 51/18639 0.0392156862745098 1.24947209653092 0.47863602568392 0.826105646726235 GO:0005030 neurotrophin receptor activity 2/585 51/18639 0.0392156862745098 1.24947209653092 0.47863602568392 0.826105646726235 GO:0005048 signal sequence binding 2/585 51/18639 0.0392156862745098 1.24947209653092 0.47863602568392 0.826105646726235 GO:0005096 GTPase activator activity 9/585 271/18639 0.033210332103321 1.05813227363043 0.479248643361882 0.826105646726235 GO:0008194 UDP-glycosyltransferase activity 5/585 145/18639 0.0344827586206897 1.09867374005305 0.479581917397925 0.826105646726235 GO:0001846 opsonin binding 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0008373 sialyltransferase activity 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0035613 RNA stem-loop binding 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0051428 peptide hormone receptor binding 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0072542 protein phosphatase activator activity 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0140312 cargo adaptor activity 1/585 21/18639 0.0476190476190476 1.51721611721612 0.488307845282782 0.826105646726235 GO:0030159 signaling receptor complex adaptor activity 2/585 52/18639 0.0384615384615385 1.22544378698225 0.488851655599952 0.826105646726235 GO:0035401 histone H3Y41 kinase activity 4/585 115/18639 0.0347826086956522 1.10822742474916 0.489218592210217 0.826105646726235 GO:0140801 histone H2AXY142 kinase activity 4/585 115/18639 0.0347826086956522 1.10822742474916 0.489218592210217 0.826105646726235 GO:0004674 protein serine/threonine kinase activity 14/585 433/18639 0.0323325635103926 1.03016521584651 0.493287451889854 0.828563906355453 GO:0004527 exonuclease activity 3/585 84/18639 0.0357142857142857 1.13791208791209 0.493542611013008 0.828563906355453 GO:0005003 ephrin receptor activity 2/585 53/18639 0.0377358490566038 1.20232220609579 0.498940885635734 0.828563906355453 GO:0005005 transmembrane-ephrin receptor activity 2/585 53/18639 0.0377358490566038 1.20232220609579 0.498940885635734 0.828563906355453 GO:0016860 intramolecular oxidoreductase activity 2/585 53/18639 0.0377358490566038 1.20232220609579 0.498940885635734 0.828563906355453 GO:0034212 protein N-acetyltransferase activity 2/585 53/18639 0.0377358490566038 1.20232220609579 0.498940885635734 0.828563906355453 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/585 53/18639 0.0377358490566038 1.20232220609579 0.498940885635734 0.828563906355453 GO:1990782 protein tyrosine kinase binding 4/585 117/18639 0.0341880341880342 1.08928336620644 0.502695567813889 0.828563906355453 GO:0005243 gap junction channel activity 1/585 22/18639 0.0454545454545455 1.44825174825175 0.504385829518981 0.828563906355453 GO:0034062 5'-3' RNA polymerase activity 1/585 22/18639 0.0454545454545455 1.44825174825175 0.504385829518981 0.828563906355453 GO:0050321 tau-protein kinase activity 1/585 22/18639 0.0454545454545455 1.44825174825175 0.504385829518981 0.828563906355453 GO:0061133 endopeptidase activator activity 1/585 22/18639 0.0454545454545455 1.44825174825175 0.504385829518981 0.828563906355453 GO:0097747 RNA polymerase activity 1/585 22/18639 0.0454545454545455 1.44825174825175 0.504385829518981 0.828563906355453 GO:0140035 ubiquitin-like protein reader activity 1/585 22/18639 0.0454545454545455 1.44825174825175 0.504385829518981 0.828563906355453 GO:0051287 NAD binding 2/585 54/18639 0.037037037037037 1.18005698005698 0.508901577349215 0.833886419056007 GO:0033218 amide binding 8/585 247/18639 0.0323886639676113 1.03195266272189 0.514386022323638 0.833886419056007 GO:0140313 molecular sequestering activity 2/585 55/18639 0.0363636363636364 1.1586013986014 0.518731850393727 0.833886419056007 GO:0000295 adenine nucleotide transmembrane transporter activity 1/585 23/18639 0.0434782608695652 1.38528428093645 0.519959460594417 0.833886419056007 GO:0005283 amino acid:sodium symporter activity 1/585 23/18639 0.0434782608695652 1.38528428093645 0.519959460594417 0.833886419056007 GO:0008171 O-methyltransferase activity 1/585 23/18639 0.0434782608695652 1.38528428093645 0.519959460594417 0.833886419056007 GO:0017134 fibroblast growth factor binding 1/585 23/18639 0.0434782608695652 1.38528428093645 0.519959460594417 0.833886419056007 GO:0070577 lysine-acetylated histone binding 1/585 23/18639 0.0434782608695652 1.38528428093645 0.519959460594417 0.833886419056007 GO:0099186 structural constituent of postsynapse 1/585 23/18639 0.0434782608695652 1.38528428093645 0.519959460594417 0.833886419056007 GO:0032182 ubiquitin-like protein binding 4/585 120/18639 0.0333333333333333 1.06205128205128 0.522611795357999 0.833886419056007 GO:0003774 cytoskeletal motor activity 5/585 153/18639 0.0326797385620915 1.0412267471091 0.527027273588637 0.833886419056007 GO:0003727 single-stranded RNA binding 3/585 89/18639 0.0337078651685393 1.07398444252377 0.532422352462111 0.833886419056007 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0004622 lysophospholipase activity 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0030215 semaphorin receptor binding 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0035035 histone acetyltransferase binding 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0050699 WW domain binding 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0060229 lipase activator activity 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0070300 phosphatidic acid binding 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0140033 acetylation-dependent protein binding 1/585 24/18639 0.0416666666666667 1.3275641025641 0.535044533410933 0.833886419056007 GO:0008528 G protein-coupled peptide receptor activity 4/585 122/18639 0.0327868852459016 1.04464060529634 0.535675679268418 0.833886419056007 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/585 122/18639 0.0327868852459016 1.04464060529634 0.535675679268418 0.833886419056007 GO:0031406 carboxylic acid binding 6/585 187/18639 0.0320855614973262 1.02229535170712 0.536059373186593 0.833886419056007 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/585 57/18639 0.0350877192982456 1.11794871794872 0.537994825925106 0.833886419056007 GO:0046943 carboxylic acid transmembrane transporter activity 6/585 188/18639 0.0319148936170213 1.01685761047463 0.541291731594044 0.833886419056007 GO:0005342 organic acid transmembrane transporter activity 6/585 189/18639 0.0317460317460317 1.01147741147741 0.546498370882952 0.833886419056007 GO:0043177 organic acid binding 6/585 189/18639 0.0317460317460317 1.01147741147741 0.546498370882952 0.833886419056007 GO:0000030 mannosyltransferase activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0004709 MAP kinase kinase kinase activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0005251 delayed rectifier potassium channel activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0008139 nuclear localization sequence binding 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0008483 transaminase activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0015645 fatty acid ligase activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0017056 structural constituent of nuclear pore 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0019211 phosphatase activator activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0047617 fatty acyl-CoA hydrolase activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0120515 fatty acid-CoA ligase activity 1/585 25/18639 0.04 1.27446153846154 0.549656349041049 0.833886419056007 GO:0052689 carboxylic ester hydrolase activity 3/585 92/18639 0.0326086956521739 1.03896321070234 0.554927389305633 0.833886419056007 GO:0141003 histone H2AX kinase activity 11/585 354/18639 0.0310734463276836 0.990047805302043 0.556583807658546 0.833886419056007 GO:0015459 potassium channel regulator activity 2/585 59/18639 0.0338983050847458 1.08005215123859 0.556719413100452 0.833886419056007 GO:0031593 polyubiquitin modification-dependent protein binding 2/585 59/18639 0.0338983050847458 1.08005215123859 0.556719413100452 0.833886419056007 GO:0070888 E-box binding 2/585 59/18639 0.0338983050847458 1.08005215123859 0.556719413100452 0.833886419056007 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0004435 phosphatidylinositol phospholipase C activity 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0005112 Notch binding 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0005227 calcium-activated cation channel activity 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0015216 purine nucleotide transmembrane transporter activity 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0016289 acyl-CoA hydrolase activity 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0019865 immunoglobulin binding 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0030507 spectrin binding 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0097602 cullin family protein binding 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0120014 phospholipid transfer activity 1/585 26/18639 0.0384615384615385 1.22544378698225 0.563809730141887 0.833886419056007 GO:0098531 ligand-modulated transcription factor activity 2/585 60/18639 0.0333333333333333 1.06205128205128 0.565877472128274 0.835181374977626 GO:0140996 histone H3 kinase activity 11/585 357/18639 0.030812324929972 0.981728075845723 0.567915519127884 0.835181374977626 GO:0016410 N-acyltransferase activity 3/585 94/18639 0.0319148936170213 1.01685761047463 0.56956664649204 0.835181374977626 GO:0030695 GTPase regulator activity 15/585 489/18639 0.0306748466257669 0.977347805568665 0.573432653988068 0.835181374977626 GO:0001653 peptide receptor activity 4/585 128/18639 0.03125 0.995673076923077 0.573749746707801 0.835181374977626 GO:0016836 hydro-lyase activity 2/585 61/18639 0.0327868852459016 1.04464060529634 0.574898506279172 0.835181374977626 GO:0019905 syntaxin binding 2/585 61/18639 0.0327868852459016 1.04464060529634 0.574898506279172 0.835181374977626 GO:0060589 nucleoside-triphosphatase regulator activity 15/585 490/18639 0.0306122448979592 0.975353218210361 0.576643148453989 0.835181374977626 GO:0005385 zinc ion transmembrane transporter activity 1/585 27/18639 0.037037037037037 1.18005698005698 0.577519035888784 0.835181374977626 GO:0008320 protein transmembrane transporter activity 1/585 27/18639 0.037037037037037 1.18005698005698 0.577519035888784 0.835181374977626 GO:0008395 steroid hydroxylase activity 1/585 27/18639 0.037037037037037 1.18005698005698 0.577519035888784 0.835181374977626 GO:0016405 CoA-ligase activity 1/585 27/18639 0.037037037037037 1.18005698005698 0.577519035888784 0.835181374977626 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/585 27/18639 0.037037037037037 1.18005698005698 0.577519035888784 0.835181374977626 GO:0035173 histone kinase activity 11/585 360/18639 0.0305555555555556 0.973547008547008 0.57912924166944 0.836080782341887 GO:0015179 L-amino acid transmembrane transporter activity 2/585 62/18639 0.032258064516129 1.02779156327543 0.583782081908292 0.838616203475222 GO:0005085 guanyl-nucleotide exchange factor activity 7/585 230/18639 0.0304347826086957 0.969698996655518 0.586230128582796 0.838616203475222 GO:0016758 hexosyltransferase activity 6/585 197/18639 0.0304568527918782 0.970402186645842 0.587153742838817 0.838616203475222 GO:0001664 G protein-coupled receptor binding 9/585 297/18639 0.0303030303030303 0.965501165501166 0.589906341446008 0.838616203475222 GO:0042578 phosphoric ester hydrolase activity 11/585 363/18639 0.0303030303030303 0.965501165501166 0.590218035827596 0.838616203475222 GO:0045499 chemorepellent activity 1/585 28/18639 0.0357142857142857 1.13791208791209 0.590798176443537 0.838616203475222 GO:0046875 ephrin receptor binding 1/585 28/18639 0.0357142857142857 1.13791208791209 0.590798176443537 0.838616203475222 GO:0051019 mitogen-activated protein kinase binding 1/585 28/18639 0.0357142857142857 1.13791208791209 0.590798176443537 0.838616203475222 GO:0051393 alpha-actinin binding 1/585 28/18639 0.0357142857142857 1.13791208791209 0.590798176443537 0.838616203475222 GO:0051959 dynein light intermediate chain binding 1/585 28/18639 0.0357142857142857 1.13791208791209 0.590798176443537 0.838616203475222 GO:0003924 GTPase activity 10/585 331/18639 0.0302114803625378 0.962584243551011 0.593795650911458 0.841459163603172 GO:0015399 primary active transmembrane transporter activity 5/585 166/18639 0.0301204819277108 0.959684893419833 0.599696570301725 0.847491553461751 GO:0004629 phospholipase C activity 1/585 29/18639 0.0344827586206897 1.09867374005305 0.603660626971747 0.847491553461751 GO:0005416 amino acid:monoatomic cation symporter activity 1/585 29/18639 0.0344827586206897 1.09867374005305 0.603660626971747 0.847491553461751 GO:0035250 UDP-galactosyltransferase activity 1/585 29/18639 0.0344827586206897 1.09867374005305 0.603660626971747 0.847491553461751 GO:0120013 lipid transfer activity 2/585 65/18639 0.0307692307692308 0.980355029585799 0.609606091751807 0.847491553461751 GO:0051087 protein-folding chaperone binding 4/585 134/18639 0.0298507462686567 0.951090700344432 0.61000456705992 0.847491553461751 GO:0015297 antiporter activity 4/585 135/18639 0.0296296296296296 0.944045584045584 0.615859763526342 0.847491553461751 GO:0015215 nucleotide transmembrane transporter activity 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0016769 transferase activity, transferring nitrogenous groups 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0022839 monoatomic ion-gated channel activity 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0031210 phosphatidylcholine binding 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0048019 receptor antagonist activity 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0070566 adenylyltransferase activity 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0098918 structural constituent of synapse 1/585 30/18639 0.0333333333333333 1.06205128205128 0.616119441223308 0.847491553461751 GO:0008235 metalloexopeptidase activity 2/585 66/18639 0.0303030303030303 0.965501165501166 0.617938591718243 0.847491553461751 GO:0016779 nucleotidyltransferase activity 4/585 136/18639 0.0294117647058824 0.93710407239819 0.621660009274246 0.847491553461751 GO:0008238 exopeptidase activity 3/585 102/18639 0.0294117647058824 0.93710407239819 0.625056067239415 0.847491553461751 GO:0008173 RNA methyltransferase activity 2/585 67/18639 0.0298507462686567 0.951090700344432 0.626133705808712 0.847491553461751 GO:0016500 protein-hormone receptor activity 2/585 67/18639 0.0298507462686567 0.951090700344432 0.626133705808712 0.847491553461751 GO:0016791 phosphatase activity 8/585 273/18639 0.0293040293040293 0.93367145674838 0.627868283443282 0.847491553461751 GO:0005164 tumor necrosis factor receptor binding 1/585 31/18639 0.032258064516129 1.02779156327543 0.628187264689607 0.847491553461751 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/585 31/18639 0.032258064516129 1.02779156327543 0.628187264689607 0.847491553461751 GO:0016878 acid-thiol ligase activity 1/585 31/18639 0.032258064516129 1.02779156327543 0.628187264689607 0.847491553461751 GO:0017147 Wnt-protein binding 1/585 31/18639 0.032258064516129 1.02779156327543 0.628187264689607 0.847491553461751 GO:0047499 calcium-independent phospholipase A2 activity 1/585 31/18639 0.032258064516129 1.02779156327543 0.628187264689607 0.847491553461751 GO:0072349 modified amino acid transmembrane transporter activity 1/585 31/18639 0.032258064516129 1.02779156327543 0.628187264689607 0.847491553461751 GO:0003777 microtubule motor activity 2/585 68/18639 0.0294117647058824 0.93710407239819 0.634191834854409 0.847491553461751 GO:0030145 manganese ion binding 2/585 68/18639 0.0294117647058824 0.93710407239819 0.634191834854409 0.847491553461751 GO:0008378 galactosyltransferase activity 1/585 32/18639 0.03125 0.995673076923077 0.639876347350644 0.847491553461751 GO:0015106 bicarbonate transmembrane transporter activity 1/585 32/18639 0.03125 0.995673076923077 0.639876347350644 0.847491553461751 GO:0022884 macromolecule transmembrane transporter activity 1/585 32/18639 0.03125 0.995673076923077 0.639876347350644 0.847491553461751 GO:0031369 translation initiation factor binding 1/585 32/18639 0.03125 0.995673076923077 0.639876347350644 0.847491553461751 GO:0140142 nucleocytoplasmic carrier activity 1/585 32/18639 0.03125 0.995673076923077 0.639876347350644 0.847491553461751 GO:0008080 N-acetyltransferase activity 2/585 69/18639 0.0289855072463768 0.923522853957637 0.642113489720431 0.847491553461751 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/585 243/18639 0.0288065843621399 0.917822095599873 0.643828129339343 0.847491553461751 GO:0019956 chemokine binding 1/585 33/18639 0.0303030303030303 0.965501165501166 0.651198556024792 0.847491553461751 GO:0140416 transcription regulator inhibitor activity 1/585 33/18639 0.0303030303030303 0.965501165501166 0.651198556024792 0.847491553461751 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0004711 ribosomal protein S6 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0035175 histone H3S10 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0035979 histone H2AXS139 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0044022 histone H3S28 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0044023 histone H4S1 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0044024 histone H2AS1 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0044025 histone H2BS14 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0072354 histone H3T3 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0072371 histone H2AS121 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0140823 histone H2BS36 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0140855 histone H3S57 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0140995 histone H2A kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0140997 histone H4 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0140998 histone H2B kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:1990244 histone H2AT120 kinase activity 7/585 245/18639 0.0285714285714286 0.91032967032967 0.652264029121739 0.847491553461751 GO:0004677 DNA-dependent protein kinase activity 7/585 246/18639 0.0284552845528455 0.906629143214509 0.656437282641351 0.847491553461751 GO:0140857 histone H3T45 kinase activity 7/585 246/18639 0.0284552845528455 0.906629143214509 0.656437282641351 0.847491553461751 GO:0035402 histone H3T11 kinase activity 7/585 247/18639 0.0283400809716599 0.902958579881657 0.660580444400618 0.847491553461751 GO:0035403 histone H3T6 kinase activity 7/585 247/18639 0.0283400809716599 0.902958579881657 0.660580444400618 0.847491553461751 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/585 484/18639 0.0289256198347107 0.921614748887476 0.660729790644573 0.847491553461751 GO:0008175 tRNA methyltransferase activity 1/585 34/18639 0.0294117647058824 0.93710407239819 0.66216538633359 0.847491553461751 GO:0008376 acetylgalactosaminyltransferase activity 1/585 34/18639 0.0294117647058824 0.93710407239819 0.66216538633359 0.847491553461751 GO:0016831 carboxy-lyase activity 1/585 34/18639 0.0294117647058824 0.93710407239819 0.66216538633359 0.847491553461751 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/585 34/18639 0.0294117647058824 0.93710407239819 0.66216538633359 0.847491553461751 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/585 34/18639 0.0294117647058824 0.93710407239819 0.66216538633359 0.847491553461751 GO:0004679 AMP-activated protein kinase activity 7/585 248/18639 0.0282258064516129 0.899317617866005 0.664693307842091 0.848636531529112 GO:0042379 chemokine receptor binding 2/585 72/18639 0.0277777777777778 0.885042735042735 0.665066217971396 0.848636531529112 GO:0004620 phospholipase activity 3/585 109/18639 0.0275229357798165 0.876923076923077 0.669425678395263 0.850790173770305 GO:0000175 3'-5'-RNA exonuclease activity 1/585 35/18639 0.0285714285714286 0.91032967032967 0.672787974293539 0.850790173770305 GO:0004623 phospholipase A2 activity 1/585 35/18639 0.0285714285714286 0.91032967032967 0.672787974293539 0.850790173770305 GO:0005154 epidermal growth factor receptor binding 1/585 35/18639 0.0285714285714286 0.91032967032967 0.672787974293539 0.850790173770305 GO:0005343 organic acid:sodium symporter activity 1/585 35/18639 0.0285714285714286 0.91032967032967 0.672787974293539 0.850790173770305 GO:0061631 ubiquitin conjugating enzyme activity 1/585 35/18639 0.0285714285714286 0.91032967032967 0.672787974293539 0.850790173770305 GO:0031491 nucleosome binding 2/585 74/18639 0.027027027027027 0.861122661122661 0.679699345583903 0.854856853527142 GO:0048029 monosaccharide binding 2/585 74/18639 0.027027027027027 0.861122661122661 0.679699345583903 0.854856853527142 GO:0022804 active transmembrane transporter activity 13/585 457/18639 0.0284463894967177 0.906345733041575 0.680692315456124 0.854856853527142 GO:0001216 DNA-binding transcription activator activity 14/585 491/18639 0.0285132382892057 0.908475638414539 0.681281876838045 0.854856853527142 GO:0015291 secondary active transmembrane transporter activity 8/585 287/18639 0.0278745644599303 0.888126507638703 0.682572865476522 0.854856853527142 GO:0000993 RNA polymerase II complex binding 1/585 36/18639 0.0277777777777778 0.885042735042735 0.68307710754651 0.854856853527142 GO:0004190 aspartic-type endopeptidase activity 1/585 36/18639 0.0277777777777778 0.885042735042735 0.68307710754651 0.854856853527142 GO:0019003 GDP binding 2/585 75/18639 0.0266666666666667 0.849641025641026 0.686818170910642 0.857003204410624 GO:0044183 protein folding chaperone 2/585 75/18639 0.0266666666666667 0.849641025641026 0.686818170910642 0.857003204410624 GO:0022829 wide pore channel activity 1/585 37/18639 0.027027027027027 0.861122661122661 0.693043236240016 0.862227320380962 GO:0070001 aspartic-type peptidase activity 1/585 37/18639 0.027027027027027 0.861122661122661 0.693043236240016 0.862227320380962 GO:0000510 H3-H4 histone complex chaperone activity 4/585 151/18639 0.0264900662251656 0.844014263881814 0.701843333490364 0.865323903713454 GO:0140584 chromatin extrusion motor activity 4/585 151/18639 0.0264900662251656 0.844014263881814 0.701843333490364 0.865323903713454 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/585 151/18639 0.0264900662251656 0.844014263881814 0.701843333490364 0.865323903713454 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/585 151/18639 0.0264900662251656 0.844014263881814 0.701843333490364 0.865323903713454 GO:0008234 cysteine-type peptidase activity 5/585 187/18639 0.0267379679144385 0.851912793089264 0.702520541004309 0.865323903713454 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/585 38/18639 0.0263157894736842 0.838461538461538 0.702696483568239 0.865323903713454 GO:0042887 amide transmembrane transporter activity 1/585 38/18639 0.0263157894736842 0.838461538461538 0.702696483568239 0.865323903713454 GO:0001221 transcription coregulator binding 3/585 115/18639 0.0260869565217391 0.831170568561873 0.704300042089684 0.865323903713454 GO:0015616 DNA translocase activity 4/585 152/18639 0.0263157894736842 0.838461538461538 0.706725678743797 0.865323903713454 GO:0140674 ATP-dependent histone chaperone activity 4/585 152/18639 0.0263157894736842 0.838461538461538 0.706725678743797 0.865323903713454 GO:0140597 protein carrier chaperone 5/585 188/18639 0.0265957446808511 0.847381342062193 0.706925699731365 0.865323903713454 GO:0009055 electron transfer activity 3/585 116/18639 0.0258620689655172 0.824005305039788 0.709830764310468 0.865323903713454 GO:0061775 cohesin loader activity 4/585 153/18639 0.0261437908496732 0.83298139768728 0.711549797002996 0.865323903713454 GO:0000217 DNA secondary structure binding 1/585 39/18639 0.0256410256410256 0.816962524654832 0.712046655984377 0.865323903713454 GO:0016835 carbon-oxygen lyase activity 2/585 79/18639 0.0253164556962025 0.806621226874391 0.714001446097359 0.865323903713454 GO:0019208 phosphatase regulator activity 3/585 117/18639 0.0256410256410256 0.816962524654832 0.715281690534063 0.865323903713454 GO:0048306 calcium-dependent protein binding 2/585 80/18639 0.025 0.796538461538462 0.72048043936119 0.865323903713454 GO:0004386 helicase activity 4/585 155/18639 0.0258064516129032 0.822233250620347 0.721023610848007 0.865323903713454 GO:0004532 RNA exonuclease activity 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:0050997 quaternary ammonium group binding 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:0061791 GTPase motor activity 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:0071855 neuropeptide receptor binding 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:0140662 ATP-dependent protein folding chaperone 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:1990606 membrane scission GTPase motor activity 1/585 40/18639 0.025 0.796538461538462 0.721103253094545 0.865323903713454 GO:0030971 receptor tyrosine kinase binding 2/585 81/18639 0.0246913580246914 0.78670465337132 0.726835342153481 0.867239682229909 GO:0001727 lipid kinase activity 1/585 41/18639 0.024390243902439 0.777110694183865 0.729875477243139 0.867239682229909 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/585 41/18639 0.024390243902439 0.777110694183865 0.729875477243139 0.867239682229909 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/585 41/18639 0.024390243902439 0.777110694183865 0.729875477243139 0.867239682229909 GO:0042169 SH2 domain binding 1/585 41/18639 0.024390243902439 0.777110694183865 0.729875477243139 0.867239682229909 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/585 41/18639 0.024390243902439 0.777110694183865 0.729875477243139 0.867239682229909 GO:0140318 protein transporter activity 1/585 41/18639 0.024390243902439 0.777110694183865 0.729875477243139 0.867239682229909 GO:0140658 ATP-dependent chromatin remodeler activity 4/585 158/18639 0.0253164556962025 0.806621226874391 0.734799826963357 0.868534712427723 GO:0051082 unfolded protein binding 3/585 121/18639 0.0247933884297521 0.789955499046408 0.736294643438655 0.868534712427723 GO:0004520 DNA endonuclease activity 1/585 42/18639 0.0238095238095238 0.758608058608059 0.738372242799261 0.868534712427723 GO:0031492 nucleosomal DNA binding 1/585 42/18639 0.0238095238095238 0.758608058608059 0.738372242799261 0.868534712427723 GO:0043175 RNA polymerase core enzyme binding 1/585 42/18639 0.0238095238095238 0.758608058608059 0.738372242799261 0.868534712427723 GO:0051879 Hsp90 protein binding 1/585 42/18639 0.0238095238095238 0.758608058608059 0.738372242799261 0.868534712427723 GO:0008135 translation factor activity, RNA binding 2/585 83/18639 0.0240963855421687 0.767747914735867 0.739178478661892 0.868534712427723 GO:0030165 PDZ domain binding 2/585 83/18639 0.0240963855421687 0.767747914735867 0.739178478661892 0.868534712427723 GO:0003689 DNA clamp loader activity 4/585 160/18639 0.025 0.796538461538462 0.743695995442189 0.871941188641411 GO:0004860 protein kinase inhibitor activity 2/585 84/18639 0.0238095238095238 0.758608058608059 0.745169597385035 0.871941188641411 GO:0180051 translation factor activity 2/585 84/18639 0.0238095238095238 0.758608058608059 0.745169597385035 0.871941188641411 GO:0008200 ion channel inhibitor activity 1/585 43/18639 0.0232558139534884 0.740966010733453 0.746602185153535 0.872410840662832 GO:0005267 potassium channel activity 3/585 124/18639 0.0241935483870968 0.770843672456576 0.751236056306129 0.876614763634462 GO:0016790 thiolester hydrolase activity 1/585 44/18639 0.0227272727272727 0.724125874125874 0.754573669434304 0.878415719914044 GO:0004842 ubiquitin-protein transferase activity 12/585 449/18639 0.0267260579064588 0.851533321911941 0.75485606191195 0.878415719914044 GO:0016829 lyase activity 5/585 200/18639 0.025 0.796538461538462 0.756224071961291 0.878798852856115 GO:0140713 histone chaperone activity 4/585 164/18639 0.024390243902439 0.777110694183865 0.760804312560023 0.88290870840299 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/585 46/18639 0.0217391304347826 0.692642140468227 0.769773423379906 0.889470589253183 GO:0031490 chromatin DNA binding 3/585 128/18639 0.0234375 0.746754807692308 0.770092894668184 0.889470589253183 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/585 89/18639 0.0224719101123595 0.715989628349179 0.773380812457815 0.889470589253183 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/585 89/18639 0.0224719101123595 0.715989628349179 0.773380812457815 0.889470589253183 GO:0035591 signaling adaptor activity 3/585 129/18639 0.0232558139534884 0.740966010733453 0.774620751077606 0.889470589253183 GO:0016247 channel regulator activity 4/585 168/18639 0.0238095238095238 0.758608058608059 0.777014108220795 0.889470589253183 GO:0001784 phosphotyrosine residue binding 1/585 47/18639 0.0212765957446809 0.677905073649754 0.777017146680221 0.889470589253183 GO:0061733 protein-lysine-acetyltransferase activity 1/585 47/18639 0.0212765957446809 0.677905073649754 0.777017146680221 0.889470589253183 GO:0019210 kinase inhibitor activity 2/585 90/18639 0.0222222222222222 0.708034188034188 0.778685027908369 0.889470589253183 GO:0140793 histone H2AXY142 phosphatase activity 2/585 90/18639 0.0222222222222222 0.708034188034188 0.778685027908369 0.889470589253183 GO:0016298 lipase activity 3/585 130/18639 0.0230769230769231 0.735266272189349 0.779075303352965 0.889470589253183 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/585 130/18639 0.0230769230769231 0.735266272189349 0.779075303352965 0.889470589253183 GO:0061630 ubiquitin protein ligase activity 9/585 353/18639 0.0254957507082153 0.812333841795598 0.781778919749108 0.889987496333469 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/585 91/18639 0.021978021978022 0.700253592561285 0.783880255205289 0.889987496333469 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/585 48/18639 0.0208333333333333 0.663782051282051 0.784033334782204 0.889987496333469 GO:0140693 molecular condensate scaffold activity 1/585 48/18639 0.0208333333333333 0.663782051282051 0.784033334782204 0.889987496333469 GO:0141108 transporter regulator activity 4/585 170/18639 0.0235294117647059 0.749683257918552 0.784788028681758 0.889987496333469 GO:0001222 transcription corepressor binding 1/585 49/18639 0.0204081632653061 0.650235478806907 0.790829123021266 0.893694535761244 GO:0060590 ATPase regulator activity 1/585 49/18639 0.0204081632653061 0.650235478806907 0.790829123021266 0.893694535761244 GO:0042393 histone binding 6/585 247/18639 0.0242914979757085 0.77396449704142 0.791226013339447 0.893694535761244 GO:0140030 modification-dependent protein binding 4/585 173/18639 0.023121387283237 0.736682970208982 0.796042866654895 0.897147128292004 GO:0032813 tumor necrosis factor receptor superfamily binding 1/585 50/18639 0.02 0.637230769230769 0.797411423345772 0.897147128292004 GO:0140104 molecular carrier activity 6/585 249/18639 0.0240963855421687 0.767747914735867 0.797464114037337 0.897147128292004 GO:0004721 phosphoprotein phosphatase activity 4/585 175/18639 0.0228571428571429 0.728263736263736 0.803279745283006 0.900667210435711 GO:0016830 carbon-carbon lyase activity 1/585 51/18639 0.0196078431372549 0.62473604826546 0.803786931299009 0.900667210435711 GO:0030544 Hsp70 protein binding 1/585 51/18639 0.0196078431372549 0.62473604826546 0.803786931299009 0.900667210435711 GO:0005080 protein kinase C binding 1/585 52/18639 0.0192307692307692 0.612721893491124 0.809962132783304 0.905194169310383 GO:0004864 protein phosphatase inhibitor activity 1/585 53/18639 0.0188679245283019 0.601161103047895 0.815943310613065 0.905194169310383 GO:0005246 calcium channel regulator activity 1/585 53/18639 0.0188679245283019 0.601161103047895 0.815943310613065 0.905194169310383 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/585 53/18639 0.0188679245283019 0.601161103047895 0.815943310613065 0.905194169310383 GO:0051018 protein kinase A binding 1/585 53/18639 0.0188679245283019 0.601161103047895 0.815943310613065 0.905194169310383 GO:0004725 protein tyrosine phosphatase activity 2/585 98/18639 0.0204081632653061 0.650235478806907 0.817330403590944 0.905194169310383 GO:0005249 voltage-gated potassium channel activity 2/585 98/18639 0.0204081632653061 0.650235478806907 0.817330403590944 0.905194169310383 GO:0016853 isomerase activity 4/585 180/18639 0.0222222222222222 0.708034188034188 0.820463165865041 0.905194169310383 GO:0015485 cholesterol binding 1/585 54/18639 0.0185185185185185 0.59002849002849 0.821736550863326 0.905194169310383 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/585 54/18639 0.0185185185185185 0.59002849002849 0.821736550863326 0.905194169310383 GO:0017069 snRNA binding 1/585 54/18639 0.0185185185185185 0.59002849002849 0.821736550863326 0.905194169310383 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/585 54/18639 0.0185185185185185 0.59002849002849 0.821736550863326 0.905194169310383 GO:0050661 NADP binding 1/585 54/18639 0.0185185185185185 0.59002849002849 0.821736550863326 0.905194169310383 GO:0019787 ubiquitin-like protein transferase activity 12/585 479/18639 0.0250521920668058 0.798201381082383 0.825118669142651 0.907737833673189 GO:0061659 ubiquitin-like protein ligase activity 9/585 372/18639 0.0241935483870968 0.770843672456576 0.829468567260481 0.911338192080996 GO:0019212 phosphatase inhibitor activity 1/585 56/18639 0.0178571428571429 0.568956043956044 0.832782615939198 0.913371685254028 GO:0015171 amino acid transmembrane transporter activity 2/585 102/18639 0.0196078431372549 0.62473604826546 0.834295369552158 0.913371685254028 GO:0003730 mRNA 3'-UTR binding 6/585 262/18639 0.0229007633587786 0.729653552554316 0.834558289245111 0.913371685254028 GO:0005253 monoatomic anion channel activity 2/585 103/18639 0.0194174757281553 0.618670649738611 0.838308411099487 0.916290588876183 GO:0005525 GTP binding 9/585 378/18639 0.0238095238095238 0.758608058608059 0.842737506612158 0.918647341485114 GO:0008408 3'-5' exonuclease activity 1/585 58/18639 0.0172413793103448 0.549336870026525 0.843145310788587 0.918647341485114 GO:0015085 calcium ion transmembrane transporter activity 3/585 147/18639 0.0204081632653061 0.650235478806907 0.844262617755003 0.918647341485114 GO:0004879 nuclear receptor activity 1/585 59/18639 0.0169491525423729 0.540026075619296 0.848083688334934 0.918647341485114 GO:0045309 protein phosphorylated amino acid binding 1/585 59/18639 0.0169491525423729 0.540026075619296 0.848083688334934 0.918647341485114 GO:0070063 RNA polymerase binding 1/585 59/18639 0.0169491525423729 0.540026075619296 0.848083688334934 0.918647341485114 GO:0001098 basal transcription machinery binding 1/585 60/18639 0.0166666666666667 0.531025641025641 0.852866844541827 0.918647341485114 GO:0001099 basal RNA polymerase II transcription machinery binding 1/585 60/18639 0.0166666666666667 0.531025641025641 0.852866844541827 0.918647341485114 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/585 60/18639 0.0166666666666667 0.531025641025641 0.852866844541827 0.918647341485114 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/585 60/18639 0.0166666666666667 0.531025641025641 0.852866844541827 0.918647341485114 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/585 60/18639 0.0166666666666667 0.531025641025641 0.852866844541827 0.918647341485114 GO:0019888 protein phosphatase regulator activity 2/585 107/18639 0.0186915887850467 0.595542774982027 0.853495047762766 0.918647341485114 GO:0016755 aminoacyltransferase activity 12/585 496/18639 0.0241935483870968 0.770843672456576 0.857605863127854 0.92189905998242 GO:1901682 sulfur compound transmembrane transporter activity 1/585 63/18639 0.0158730158730159 0.505738705738706 0.866332934658476 0.930098556752628 GO:0008017 microtubule binding 6/585 276/18639 0.0217391304347826 0.692642140468227 0.868196426192886 0.930917841012905 GO:0004536 DNA nuclease activity 1/585 64/18639 0.015625 0.497836538461538 0.870542411037933 0.932251746503913 GO:0160215 deacylase activity 1/585 65/18639 0.0153846153846154 0.490177514792899 0.874619541026779 0.935433794827629 GO:0015079 potassium ion transmembrane transporter activity 3/585 160/18639 0.01875 0.597403846153846 0.88220100708964 0.940130361970251 GO:0099106 ion channel regulator activity 3/585 160/18639 0.01875 0.597403846153846 0.88220100708964 0.940130361970251 GO:0015294 solute:monoatomic cation symporter activity 2/585 116/18639 0.0172413793103448 0.549336870026525 0.883016881702639 0.940130361970251 GO:0019001 guanyl nucleotide binding 9/585 400/18639 0.0225 0.716884615384615 0.884567101806524 0.940130361970251 GO:0032561 guanyl ribonucleotide binding 9/585 400/18639 0.0225 0.716884615384615 0.884567101806524 0.940130361970251 GO:0140223 general transcription initiation factor activity 1/585 68/18639 0.0147058823529412 0.468552036199095 0.886097746698396 0.94057552535363 GO:0002039 p53 binding 1/585 69/18639 0.0144927536231884 0.461761426978818 0.889685750477484 0.943200682837032 GO:0008094 ATP-dependent activity, acting on DNA 4/585 210/18639 0.019047619047619 0.606886446886447 0.899283274474289 0.952182290619836 GO:0035064 methylated histone binding 1/585 74/18639 0.0135135135135135 0.430561330561331 0.906002414403946 0.958097553232173 GO:0005244 voltage-gated monoatomic ion channel activity 3/585 173/18639 0.0173410404624277 0.552512227656736 0.911687466629365 0.96185889165195 GO:0140034 methylation-dependent protein binding 1/585 76/18639 0.0131578947368421 0.419230769230769 0.911833133693692 0.96185889165195 GO:0022832 voltage-gated channel activity 3/585 175/18639 0.0171428571428571 0.546197802197802 0.9155774791435 0.964605912024161 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/585 130/18639 0.0153846153846154 0.490177514792899 0.918191118951799 0.965815369449078 GO:0015370 solute:sodium symporter activity 1/585 79/18639 0.0126582278481013 0.403310613437196 0.919909177221824 0.965815369449078 GO:0005262 calcium channel activity 2/585 131/18639 0.0152671755725191 0.486435701702877 0.920280016923852 0.965815369449078 GO:0140098 catalytic activity, acting on RNA 8/585 387/18639 0.020671834625323 0.658636453985291 0.922188050739683 0.965815369449078 GO:0000049 tRNA binding 1/585 80/18639 0.0125 0.398269230769231 0.922433591625124 0.965815369449078 GO:0005254 chloride channel activity 1/585 83/18639 0.0120481927710843 0.383873957367933 0.929540120830813 0.971325432878292 GO:0140789 histone phosphatase activity 2/585 136/18639 0.0147058823529412 0.468552036199095 0.929992435734534 0.971325432878292 GO:0051117 ATPase binding 1/585 84/18639 0.0119047619047619 0.379304029304029 0.931761452438594 0.971973105749754 GO:0140101 catalytic activity, acting on a tRNA 2/585 139/18639 0.0143884892086331 0.458439402324294 0.935271754213777 0.973989050633883 GO:0016209 antioxidant activity 1/585 86/18639 0.0116279069767442 0.370483005366726 0.935996569935398 0.973989050633883 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/585 88/18639 0.0113636363636364 0.362062937062937 0.939969262925061 0.976921371541279 GO:0022843 voltage-gated monoatomic cation channel activity 2/585 143/18639 0.013986013986014 0.445615922538999 0.941726406019816 0.97754667422425 GO:0015293 symporter activity 2/585 146/18639 0.0136986301369863 0.436459430979979 0.946161138492357 0.980137975490664 GO:0046982 protein heterodimerization activity 7/585 369/18639 0.018970189701897 0.604419428809673 0.946755913593139 0.980137975490664 GO:0051213 dioxygenase activity 1/585 93/18639 0.010752688172043 0.342597187758478 0.948856976272877 0.980137975490664 GO:0051219 phosphoprotein binding 1/585 93/18639 0.010752688172043 0.342597187758478 0.948856976272877 0.980137975490664 GO:0008509 monoatomic anion transmembrane transporter activity 2/585 149/18639 0.0134228187919463 0.427671657201859 0.950273471445002 0.980404093710331 GO:0140097 catalytic activity, acting on DNA 6/585 336/18639 0.0178571428571429 0.568956043956044 0.95481320513063 0.982894904493165 GO:0030594 neurotransmitter receptor activity 1/585 97/18639 0.0103092783505155 0.328469468675654 0.955011361103288 0.982894904493165 GO:0004722 protein serine/threonine phosphatase activity 1/585 103/18639 0.00970873786407767 0.309335324869305 0.962884557597887 0.989793846570854 GO:0004843 cysteine-type deubiquitinase activity 1/585 108/18639 0.00925925925925926 0.295014245014245 0.968383766126345 0.993983699789232 GO:0016874 ligase activity 2/585 167/18639 0.0119760479041916 0.381575310916628 0.969310345539145 0.993983699789232 GO:0046873 metal ion transmembrane transporter activity 8/585 450/18639 0.0177777777777778 0.56642735042735 0.973625409034282 0.995933423183458 GO:0017124 SH3 domain binding 1/585 115/18639 0.00869565217391304 0.277056856187291 0.974743350349767 0.995933423183458 GO:0101005 deubiquitinase activity 1/585 115/18639 0.00869565217391304 0.277056856187291 0.974743350349767 0.995933423183458 GO:0022853 active monoatomic ion transmembrane transporter activity 1/585 118/18639 0.00847457627118644 0.270013037809648 0.977061563186021 0.996510434409713 GO:0003697 single-stranded DNA binding 1/585 121/18639 0.00826446280991736 0.263318499682136 0.979167326155432 0.996510434409713 GO:0015108 chloride transmembrane transporter activity 1/585 121/18639 0.00826446280991736 0.263318499682136 0.979167326155432 0.996510434409713 GO:0015078 proton transmembrane transporter activity 2/585 185/18639 0.0108108108108108 0.344449064449064 0.981226727639989 0.996510434409713 GO:0019783 ubiquitin-like protein peptidase activity 1/585 127/18639 0.0078740157480315 0.250878255602665 0.982817484323894 0.996510434409713 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/585 128/18639 0.0078125 0.248918269230769 0.983360471125457 0.996510434409713 GO:0005261 monoatomic cation channel activity 5/585 341/18639 0.0146627565982405 0.467177983307016 0.983553442945757 0.996510434409713 GO:0099094 ligand-gated monoatomic cation channel activity 1/585 136/18639 0.00735294117647059 0.234276018099548 0.987130914924518 0.998725742655174 GO:0005216 monoatomic ion channel activity 7/585 448/18639 0.015625 0.497836538461538 0.988101000712034 0.998725742655174 GO:0022836 gated channel activity 4/585 318/18639 0.0125786163522013 0.400774068698597 0.990770405384946 0.999989495830715 GO:0015081 sodium ion transmembrane transporter activity 1/585 164/18639 0.00609756097560976 0.194277673545966 0.994769003275565 0.999989495830715 GO:0015103 inorganic anion transmembrane transporter activity 1/585 165/18639 0.00606060606060606 0.193100233100233 0.994934639707705 0.999989495830715 GO:0003735 structural constituent of ribosome 1/585 175/18639 0.00571428571428571 0.182065934065934 0.996328639906912 0.999989495830715 GO:0015276 ligand-gated monoatomic ion channel activity 1/585 186/18639 0.00537634408602151 0.171298593879239 0.997423818839359 0.999989495830715 GO:0022834 ligand-gated channel activity 1/585 188/18639 0.00531914893617021 0.169476268412439 0.99758457501957 0.999989495830715 GO:1903231 mRNA base-pairing translational repressor activity 1/585 298/18639 0.00335570469798658 0.106917914300465 0.999930948876348 0.999989495830715 GO:0030371 translation repressor activity 1/585 329/18639 0.00303951367781155 0.0968435819499649 0.999974742319446 0.999989495830715 GO:0045182 translation regulator activity 1/585 356/18639 0.00280898876404494 0.0894987035436474 0.999989495830715 0.999989495830715