ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0023023	MHC protein complex binding	18/1277	37/18639	0.486486486486487	7.10072170839594	4.97666741118798e-12	5.45940415007321e-09
GO:0023026	MHC class II protein complex binding	15/1277	27/18639	0.555555555555556	8.10884886452623	2.52143794945382e-11	1.38300871527542e-08
GO:0019003	GDP binding	21/1277	75/18639	0.28	4.08685982772122	1.78131061521975e-08	5.70135641801624e-06
GO:0042605	peptide antigen binding	16/1277	45/18639	0.355555555555556	5.18966327329679	2.07889021623199e-08	5.70135641801624e-06
GO:0042277	peptide binding	41/1277	249/18639	0.164658634538153	2.40334556707645	1.40778326433666e-07	3.08867648195463e-05
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	16/1277	54/18639	0.296296296296296	4.32471939441399	3.76580666756622e-07	6.88514985720024e-05
GO:0035325	Toll-like receptor binding	8/1277	13/18639	0.615384615384615	8.98210951147521	4.48159065007779e-07	7.02329277590763e-05
GO:0016798	hydrolase activity, acting on glycosyl bonds	26/1277	130/18639	0.2	2.91918559122944	6.40315568133954e-07	8.78032722803684e-05
GO:0140375	immune receptor activity	29/1277	156/18639	0.185897435897436	2.71334558159147	7.39912596943527e-07	9.01871243163388e-05
GO:0015399	primary active transmembrane transporter activity	30/1277	166/18639	0.180722891566265	2.63781830532781	8.94921750949949e-07	9.81729160792094e-05
GO:0005525	GTP binding	52/1277	378/18639	0.137566137566138	2.00790543312078	1.16335963989561e-06	0.00011387999205965
GO:0022853	active monoatomic ion transmembrane transporter activity	24/1277	118/18639	0.203389830508475	2.96866331311469	1.24572461687858e-06	0.00011387999205965
GO:0003924	GTPase activity	47/1277	331/18639	0.141993957703928	2.07253357685474	1.54804400204255e-06	0.000121699066332495
GO:0042625	ATPase-coupled ion transmembrane transporter activity	10/1277	24/18639	0.416666666666667	6.08163664839468	1.77512000097758e-06	0.000121699066332495
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	10/1277	24/18639	0.416666666666667	6.08163664839468	1.77512000097758e-06	0.000121699066332495
GO:0046961	proton-transporting ATPase activity, rotational mechanism	10/1277	24/18639	0.416666666666667	6.08163664839468	1.77512000097758e-06	0.000121699066332495
GO:0022804	active transmembrane transporter activity	59/1277	457/18639	0.12910284463895	1.88437581928378	1.88594724489737e-06	0.000121699066332495
GO:0003925	G protein activity	15/1277	54/18639	0.277777777777778	4.05442443226312	2.15750909061226e-06	0.000131488192911203
GO:0019001	guanyl nucleotide binding	53/1277	400/18639	0.1325	1.93396045418951	2.89125299550429e-06	0.00015858522680341
GO:0032561	guanyl ribonucleotide binding	53/1277	400/18639	0.1325	1.93396045418951	2.89125299550429e-06	0.00015858522680341
GO:0008238	exopeptidase activity	21/1277	102/18639	0.205882352941176	3.00504399097149	4.6275823479126e-06	0.000241736087412387
GO:0038024	cargo receptor activity	16/1277	65/18639	0.246153846153846	3.59284380459009	5.64746932961767e-06	0.000281603357026845
GO:0046915	transition metal ion transmembrane transporter activity	13/1277	45/18639	0.288888888888889	4.21660140955364	6.36357633526422e-06	0.000303514923468906
GO:0001618	virus receptor activity	18/1277	81/18639	0.222222222222222	3.24353954581049	7.13345000688192e-06	0.000326058110731228
GO:0140272	exogenous protein binding	18/1277	82/18639	0.219512195121951	3.20398418549573	8.56110757054165e-06	0.000375661400195368
GO:0042626	ATPase-coupled transmembrane transporter activity	20/1277	98/18639	0.204081632653061	2.97876080737698	8.90682906883851e-06	0.000375799672635225
GO:0009055	electron transfer activity	22/1277	116/18639	0.189655172413793	2.7681932330624	1.1207911676364e-05	0.000455373300332272
GO:0005178	integrin binding	27/1277	161/18639	0.167701863354037	2.44776431562717	1.30938139623581e-05	0.000512996925596675
GO:0015078	proton transmembrane transporter activity	29/1277	185/18639	0.156756756756757	2.28801032826092	2.39653236358482e-05	0.000906550345811224
GO:0003779	actin binding	54/1277	443/18639	0.121896162528217	1.77918760639266	2.66269993122855e-05	0.000973660608185908
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	23/1277	132/18639	0.174242424242424	2.54322987114686	2.99630752028032e-05	0.00106030624185404
GO:0042608	T cell receptor binding	6/1277	11/18639	0.545454545454545	7.96141524880757	3.49952489463495e-05	0.00117076627231665
GO:0120015	sterol transfer activity	10/1277	32/18639	0.3125	4.56122748629601	3.52190400970369e-05	0.00117076627231665
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	18/1277	91/18639	0.197802197802198	2.88710662868846	3.83950904746441e-05	0.00123880630149072
GO:0030246	carbohydrate binding	38/1277	280/18639	0.135714285714286	1.98087593690569	4.19330040130802e-05	0.00131430015435283
GO:0032934	sterol binding	15/1277	68/18639	0.220588235294118	3.21968999032659	4.46348148072851e-05	0.00136012199565533
GO:0042287	MHC protein binding	11/1277	41/18639	0.268292682926829	3.91598067116145	6.97034829481014e-05	0.00206661407551533
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	21/1277	122/18639	0.172131147540984	2.51241382851714	7.85550651090769e-05	0.00226776069538572
GO:0051015	actin filament binding	30/1277	209/18639	0.143540669856459	2.09510927600199	9.42994226756375e-05	0.00265247350449165
GO:0017154	semaphorin receptor activity	6/1277	13/18639	0.461538461538462	6.73658213360641	0.000115328067358095	0.00316287224729576
GO:0019955	cytokine binding	23/1277	144/18639	0.159722222222222	2.33129404855129	0.000120440026231044	0.00322250509208427
GO:0005496	steroid binding	19/1277	108/18639	0.175925925925926	2.56780214043331	0.000125556582097306	0.00327941834668439
GO:0043394	proteoglycan binding	10/1277	37/18639	0.27027027027027	3.9448453935533	0.000138826923516475	0.00348854651954985
GO:0016790	thiolester hydrolase activity	11/1277	44/18639	0.25	3.6489819890368	0.000139923470246302	0.00348854651954985
GO:0061134	peptidase regulator activity	31/1277	226/18639	0.13716814159292	2.00209631256887	0.000169593924177728	0.00413432299606596
GO:0047617	fatty acyl-CoA hydrolase activity	8/1277	25/18639	0.32	4.67069694596711	0.000179168276357699	0.00418186381200842
GO:0120020	cholesterol transfer activity	8/1277	25/18639	0.32	4.67069694596711	0.000179168276357699	0.00418186381200842
GO:0044389	ubiquitin-like protein ligase binding	40/1277	322/18639	0.124223602484472	1.81315875231642	0.000190099713595637	0.00425660034704793
GO:0044548	S100 protein binding	6/1277	14/18639	0.428571428571429	6.25539769549167	0.000190130735647537	0.00425660034704793
GO:0071813	lipoprotein particle binding	9/1277	32/18639	0.28125	4.10510473766641	0.000214636571554357	0.00461679056853196
GO:0071814	protein-lipid complex binding	9/1277	32/18639	0.28125	4.10510473766641	0.000214636571554357	0.00461679056853196
GO:0015485	cholesterol binding	12/1277	54/18639	0.222222222222222	3.24353954581049	0.000235845650481316	0.00487453886857271
GO:0016289	acyl-CoA hydrolase activity	8/1277	26/18639	0.307692307692308	4.49105475573761	0.000243350598481981	0.00487453886857271
GO:0070006	metalloaminopeptidase activity	8/1277	26/18639	0.307692307692308	4.49105475573761	0.000243350598481981	0.00487453886857271
GO:0042288	MHC class I protein binding	7/1277	20/18639	0.35	5.10857478465153	0.000244393471077028	0.00487453886857271
GO:0004177	aminopeptidase activity	10/1277	40/18639	0.25	3.6489819890368	0.000279856639009015	0.00524435789461817
GO:0004090	carbonyl reductase (NADPH) activity	5/1277	10/18639	0.5	7.29796397807361	0.000282057534897422	0.00524435789461817
GO:0032395	MHC class II receptor activity	5/1277	10/18639	0.5	7.29796397807361	0.000282057534897422	0.00524435789461817
GO:1905394	retromer complex binding	5/1277	10/18639	0.5	7.29796397807361	0.000282057534897422	0.00524435789461817
GO:0005543	phospholipid binding	55/1277	497/18639	0.110663983903421	1.61524353639456	0.000295958828323024	0.00541111391117262
GO:0061135	endopeptidase regulator activity	26/1277	184/18639	0.141304347826087	2.06246808075993	0.000344675134223402	0.00619850200398479
GO:0015101	organic cation transmembrane transporter activity	15/1277	81/18639	0.185185185185185	2.70294962150874	0.000354262710216981	0.0062681644049682
GO:0045296	cadherin binding	40/1277	334/18639	0.119760479041916	1.74801532408949	0.00040605068149516	0.00707043805714587
GO:0048029	monosaccharide binding	14/1277	74/18639	0.189189189189189	2.76139177548731	0.000439322025753605	0.00736921909545078
GO:0016229	steroid dehydrogenase activity	9/1277	35/18639	0.257142857142857	3.753238617295	0.0004484278395312	0.00736921909545078
GO:0000062	fatty-acyl-CoA binding	6/1277	16/18639	0.375	5.47347298355521	0.000450079926522518	0.00736921909545078
GO:0055102	lipase inhibitor activity	6/1277	16/18639	0.375	5.47347298355521	0.000450079926522518	0.00736921909545078
GO:0008235	metalloexopeptidase activity	13/1277	66/18639	0.196969696969697	2.87495550651385	0.000464205434159039	0.00748872590106568
GO:0003725	double-stranded RNA binding	14/1277	75/18639	0.186666666666667	2.72457321848081	0.000506648382501514	0.00805497500875596
GO:0004033	aldo-keto reductase (NADPH) activity	9/1277	36/18639	0.25	3.6489819890368	0.000561944717561472	0.00880647650235621
GO:0005126	cytokine receptor binding	34/1277	275/18639	0.123636363636364	1.80458745639638	0.000605999632038624	0.00936312107530099
GO:0004602	glutathione peroxidase activity	7/1277	23/18639	0.304347826086957	4.44223894317524	0.000644461185040245	0.00958697137663365
GO:0036041	long-chain fatty acid binding	6/1277	17/18639	0.352941176470588	5.15150398452255	0.000655444715813604	0.00958697137663365
GO:0048038	quinone binding	6/1277	17/18639	0.352941176470588	5.15150398452255	0.000655444715813604	0.00958697137663365
GO:1901567	fatty acid derivative binding	6/1277	17/18639	0.352941176470588	5.15150398452255	0.000655444715813604	0.00958697137663365
GO:0004859	phospholipase inhibitor activity	5/1277	12/18639	0.416666666666667	6.08163664839468	0.000789384429021928	0.0112461651771046
GO:0070008	serine-type exopeptidase activity	5/1277	12/18639	0.416666666666667	6.08163664839468	0.000789384429021928	0.0112461651771046
GO:0033218	amide binding	31/1277	247/18639	0.125506072874494	1.83187759773508	0.000803992134291017	0.0113074278374006
GO:0033293	monocarboxylic acid binding	14/1277	79/18639	0.177215189873418	2.58662014412736	0.000870573644672452	0.0120723341776926
GO:0004197	cysteine-type endopeptidase activity	15/1277	88/18639	0.170454545454545	2.48794226525237	0.000880389001107936	0.0120723341776926
GO:0016854	racemase and epimerase activity	6/1277	18/18639	0.333333333333333	4.86530931871574	0.00092652120152416	0.0123950458301464
GO:0030228	lipoprotein particle receptor activity	6/1277	18/18639	0.333333333333333	4.86530931871574	0.00092652120152416	0.0123950458301464
GO:0008374	O-acyltransferase activity	11/1277	55/18639	0.2	2.91918559122944	0.00109100816534129	0.0144111281953424
GO:0005504	fatty acid binding	10/1277	47/18639	0.212765957446809	3.1055165864143	0.00110349568679012	0.0144111281953424
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/1277	32/18639	0.25	3.6489819890368	0.00113393934281277	0.014634487753713
GO:0008035	high-density lipoprotein particle binding	5/1277	13/18639	0.384615384615385	5.61381844467201	0.00121066965506183	0.0154430768791026
GO:0120227	acyl-CoA binding	6/1277	19/18639	0.315789473684211	4.60924040720439	0.00127623879285986	0.016092344319164
GO:0038187	pattern recognition receptor activity	10/1277	48/18639	0.208333333333333	3.04081832419734	0.0013096364111214	0.0163258084431838
GO:0120013	lipid transfer activity	12/1277	65/18639	0.184615384615385	2.69463285344256	0.0013794696559104	0.0170031259835248
GO:0016504	peptidase activator activity	11/1277	57/18639	0.192982456140351	2.8167580266249	0.00148382667055341	0.0180861984177454
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/1277	14/18639	0.357142857142857	5.21283141290972	0.0017776357214031	0.0214293009492219
GO:0005044	scavenger receptor activity	7/1277	27/18639	0.259259259259259	3.78412947011224	0.00183395859844164	0.0218679628531573
GO:0016209	antioxidant activity	14/1277	86/18639	0.162790697674419	2.37608129518676	0.00203185575583558	0.0239671587543186
GO:0004896	cytokine receptor activity	15/1277	96/18639	0.15625	2.280613743148	0.00217462636149302	0.0253783523250835
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/1277	60/18639	0.183333333333333	2.67592012529366	0.00228356923601361	0.0263115897834922
GO:0051537	2 iron, 2 sulfur cluster binding	7/1277	28/18639	0.25	3.6489819890368	0.00230256391906586	0.0263115897834922
GO:0005080	protein kinase C binding	10/1277	52/18639	0.192307692307692	2.806909222336	0.00246964046040014	0.0273400492764089
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	10/1277	52/18639	0.192307692307692	2.806909222336	0.00246964046040014	0.0273400492764089
GO:0005041	low-density lipoprotein particle receptor activity	5/1277	15/18639	0.333333333333333	4.86530931871574	0.00251717864805588	0.0273400492764089
GO:0015929	hexosaminidase activity	5/1277	15/18639	0.333333333333333	4.86530931871574	0.00251717864805588	0.0273400492764089
GO:0050700	CARD domain binding	5/1277	15/18639	0.333333333333333	4.86530931871574	0.00251717864805588	0.0273400492764089
GO:0004175	endopeptidase activity	43/1277	405/18639	0.106172839506173	1.54969111633168	0.00284574379822103	0.0304419881642463
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	7/1277	29/18639	0.241379310344828	3.52315502389761	0.00285827236182075	0.0304419881642463
GO:0061133	endopeptidase activator activity	6/1277	22/18639	0.272727272727273	3.98070762440379	0.00293966549460983	0.0306417760064628
GO:0048306	calcium-dependent protein binding	13/1277	80/18639	0.1625	2.37183829287392	0.00294022441373624	0.0306417760064628
GO:0015179	L-amino acid transmembrane transporter activity	11/1277	62/18639	0.17741935483871	2.58960012125193	0.00298846619342157	0.0306417760064628
GO:0031625	ubiquitin protein ligase binding	34/1277	302/18639	0.112582781456954	1.64325016724836	0.0029887602850424	0.0306417760064628
GO:0051020	GTPase binding	35/1277	315/18639	0.111111111111111	1.62176977290525	0.00324934166711001	0.0329061129210859
GO:0005381	iron ion transmembrane transporter activity	4/1277	10/18639	0.4	5.83837118245889	0.00329496885002083	0.0329061129210859
GO:0050661	NADP binding	10/1277	54/18639	0.185185185185185	2.70294962150874	0.00329961022909703	0.0329061129210859
GO:0022858	alanine transmembrane transporter activity	5/1277	16/18639	0.3125	4.56122748629601	0.00345676897602559	0.0341628429432439
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/1277	30/18639	0.233333333333333	3.40571652310102	0.00351113208549371	0.0343902848016661
GO:0140313	molecular sequestering activity	10/1277	55/18639	0.181818181818182	2.65380508293586	0.00379041068770942	0.0367971727824534
GO:0043178	alcohol binding	14/1277	92/18639	0.152173913043478	2.22111947158762	0.00385198813633867	0.0370669384698555
GO:0005200	structural constituent of cytoskeleton	16/1277	112/18639	0.142857142857143	2.08513256516389	0.00398912322619037	0.0380527667750508
GO:1901981	phosphatidylinositol phosphate binding	23/1277	185/18639	0.124324324324324	1.81462888103452	0.00402818795867852	0.0380941568161236
GO:0001540	amyloid-beta binding	13/1277	83/18639	0.156626506024096	2.28610919795077	0.0040827116173821	0.0382797832843432
GO:0016411	acylglycerol O-acyltransferase activity	7/1277	31/18639	0.225806451612903	3.29585469977518	0.00427151246251324	0.0397105861981104
GO:0004857	enzyme inhibitor activity	43/1277	416/18639	0.103365384615385	1.5087137070056	0.00462354066734082	0.0409073725589137
GO:0004029	aldehyde dehydrogenase (NAD+) activity	5/1277	17/18639	0.294117647058824	4.29291998710212	0.00462398741778058	0.0409073725589137
GO:0008429	phosphatidylethanolamine binding	5/1277	17/18639	0.294117647058824	4.29291998710212	0.00462398741778058	0.0409073725589137
GO:0008484	sulfuric ester hydrolase activity	5/1277	17/18639	0.294117647058824	4.29291998710212	0.00462398741778058	0.0409073725589137
GO:0030169	low-density lipoprotein particle binding	5/1277	17/18639	0.294117647058824	4.29291998710212	0.00462398741778058	0.0409073725589137
GO:0032977	membrane insertase activity	5/1277	17/18639	0.294117647058824	4.29291998710212	0.00462398741778058	0.0409073725589137
GO:0015295	solute:proton symporter activity	6/1277	24/18639	0.25	3.6489819890368	0.00471415923910456	0.0413714614823816
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/1277	11/18639	0.363636363636364	5.30761016587172	0.00489898375106704	0.04204602201739
GO:0047676	arachidonate-CoA ligase activity	4/1277	11/18639	0.363636363636364	5.30761016587172	0.00489898375106704	0.04204602201739
GO:0046943	carboxylic acid transmembrane transporter activity	23/1277	188/18639	0.122340425531915	1.78567203718822	0.00491307476329667	0.04204602201739
GO:0004601	peroxidase activity	10/1277	57/18639	0.175438596491228	2.56068911511355	0.0049443362262929	0.04204602201739
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/1277	40/18639	0.2	2.91918559122944	0.00509365348932495	0.0428210146001292
GO:0022884	macromolecule transmembrane transporter activity	7/1277	32/18639	0.21875	3.1928592404072	0.00515003293602937	0.0428210146001292
GO:0017124	SH3 domain binding	16/1277	115/18639	0.139130434782609	2.0307378025944	0.00518386361893143	0.0428210146001292
GO:0005319	lipid transporter activity	22/1277	178/18639	0.123595505617978	1.80399109570359	0.00519160888041676	0.0428210146001292
GO:0005342	organic acid transmembrane transporter activity	23/1277	189/18639	0.121693121693122	1.77622403699146	0.00524170347218831	0.0429115575297804
GO:0002020	protease binding	18/1277	136/18639	0.132352941176471	1.93181399419596	0.00537364850922288	0.0433447971663052
GO:0044325	transmembrane transporter binding	18/1277	136/18639	0.132352941176471	1.93181399419596	0.00537364850922288	0.0433447971663052
GO:0008514	organic anion transmembrane transporter activity	30/1277	269/18639	0.111524163568773	1.62779865681939	0.00580243064577435	0.0454284967129269
GO:0005537	D-mannose binding	6/1277	25/18639	0.24	3.50302270947533	0.00584919830549505	0.0454284967129269
GO:0015662	P-type ion transporter activity	6/1277	25/18639	0.24	3.50302270947533	0.00584919830549505	0.0454284967129269
GO:0140358	P-type transmembrane transporter activity	6/1277	25/18639	0.24	3.50302270947533	0.00584919830549505	0.0454284967129269
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/1277	41/18639	0.195121951219512	2.84798594266287	0.00595640178556855	0.0454284967129269
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/1277	41/18639	0.195121951219512	2.84798594266287	0.00595640178556855	0.0454284967129269
GO:0140318	protein transporter activity	8/1277	41/18639	0.195121951219512	2.84798594266287	0.00595640178556855	0.0454284967129269
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/1277	18/18639	0.277777777777778	4.05442443226312	0.00604608980864843	0.0454284967129269
GO:0032393	MHC class I receptor activity	5/1277	18/18639	0.277777777777778	4.05442443226312	0.00604608980864843	0.0454284967129269
GO:0034185	apolipoprotein binding	5/1277	18/18639	0.277777777777778	4.05442443226312	0.00604608980864843	0.0454284967129269
GO:0140311	protein sequestering activity	7/1277	33/18639	0.212121212121212	3.09610593009183	0.00615748898519857	0.0459507851480465
GO:0001786	phosphatidylserine binding	10/1277	59/18639	0.169491525423729	2.47388609426224	0.00635706932369929	0.0468033895845512
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/1277	59/18639	0.169491525423729	2.47388609426224	0.00635706932369929	0.0468033895845512
GO:0031267	small GTPase binding	31/1277	283/18639	0.109540636042403	1.59884723194546	0.00660283395340828	0.0482887256459259
GO:0016651	oxidoreductase activity, acting on NAD(P)H	13/1277	88/18639	0.147727272727273	2.15621662988538	0.00676111916160416	0.0491188590747004
GO:0035091	phosphatidylinositol binding	31/1277	284/18639	0.109154929577465	1.593217488171	0.0069408584119459	0.0495344182017031
GO:0035251	UDP-glucosyltransferase activity	4/1277	12/18639	0.333333333333333	4.86530931871574	0.00695378341208959	0.0495344182017031
GO:0097677	STAT family protein binding	4/1277	12/18639	0.333333333333333	4.86530931871574	0.00695378341208959	0.0495344182017031
GO:0004866	endopeptidase inhibitor activity	20/1277	161/18639	0.124223602484472	1.81315875231642	0.00706652915446763	0.0500127902093612
GO:0008237	metallopeptidase activity	22/1277	184/18639	0.119565217391304	1.74516529910456	0.00764052406040266	0.0533947781707897
GO:0008028	monocarboxylic acid transmembrane transporter activity	11/1277	70/18639	0.157142857142857	2.29364582168028	0.00772668919623191	0.0533947781707897
GO:0015245	fatty acid transmembrane transporter activity	5/1277	19/18639	0.263157894736842	3.84103367267032	0.00774960802857294	0.0533947781707897
GO:0046527	glucosyltransferase activity	5/1277	19/18639	0.263157894736842	3.84103367267032	0.00774960802857294	0.0533947781707897
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	26/1277	229/18639	0.11353711790393	1.65717959327436	0.00778775251351536	0.0533947781707897
GO:0019905	syntaxin binding	10/1277	61/18639	0.163934426229508	2.39277507477823	0.00806487678408637	0.0549513654170357
GO:0004364	glutathione transferase activity	6/1277	27/18639	0.222222222222222	3.24353954581049	0.00869602171996653	0.0585247596736398
GO:0005385	zinc ion transmembrane transporter activity	6/1277	27/18639	0.222222222222222	3.24353954581049	0.00869602171996653	0.0585247596736398
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/1277	53/18639	0.169811320754717	2.47855380387406	0.00929430431644667	0.062169828263061
GO:0030955	potassium ion binding	4/1277	13/18639	0.307692307692308	4.49105475573761	0.00950627841521305	0.0632023480090225
GO:0016505	peptidase activator activity involved in apoptotic process	5/1277	20/18639	0.25	3.6489819890368	0.00975999129927021	0.0644982557548158
GO:0005484	SNAP receptor activity	7/1277	36/18639	0.194444444444444	2.83809710258418	0.0100624670463938	0.0660989601790061
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	9/1277	54/18639	0.166666666666667	2.43265465935787	0.0104932431339166	0.0681129450763699
GO:0051287	NAD binding	9/1277	54/18639	0.166666666666667	2.43265465935787	0.0104932431339166	0.0681129450763699
GO:0030414	peptidase inhibitor activity	20/1277	169/18639	0.118343195266272	1.72732875220677	0.0118310254318831	0.0763449111692695
GO:0004180	carboxypeptidase activity	8/1277	46/18639	0.173913043478261	2.53842225324299	0.0120273861084688	0.0771581436315223
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/1277	21/18639	0.238095238095238	3.47522094193981	0.0121012904155483	0.0771809045689333
GO:0043236	laminin binding	6/1277	29/18639	0.206896551724138	3.0198471633408	0.0124174536816898	0.0787395762359171
GO:0000149	SNARE binding	14/1277	106/18639	0.132075471698113	1.92776406967982	0.013337688697673	0.0840887615019956
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	12/1277	86/18639	0.13953488372093	2.03664111016008	0.0140289979929871	0.0879417759903251
GO:0001968	fibronectin binding	6/1277	30/18639	0.2	2.91918559122944	0.0146440340807388	0.0907599174382511
GO:0031210	phosphatidylcholine binding	6/1277	30/18639	0.2	2.91918559122944	0.0146440340807388	0.0907599174382511
GO:0003823	antigen binding	20/1277	174/18639	0.114942528735632	1.67769286852267	0.0159210981802982	0.0981204758639725
GO:0004467	long-chain fatty acid-CoA ligase activity	4/1277	15/18639	0.266666666666667	3.89224745497259	0.0162633925271665	0.0991163422350093
GO:0017081	chloride channel regulator activity	4/1277	15/18639	0.266666666666667	3.89224745497259	0.0162633925271665	0.0991163422350093
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	9/1277	58/18639	0.155172413793103	2.2648853725056	0.0164738462617841	0.09984425054794
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	10/1277	68/18639	0.147058823529412	2.14645999355106	0.016911784795714	0.101935318246694
GO:0005164	tumor necrosis factor receptor binding	6/1277	31/18639	0.193548387096774	2.82501831409301	0.0171334392691129	0.10270701026348
GO:0060590	ATPase regulator activity	8/1277	49/18639	0.163265306122449	2.38300864590159	0.0173582173510833	0.103488937142057
GO:0061791	GTPase motor activity	7/1277	40/18639	0.175	2.55428739232576	0.0177285003884074	0.104239860643479
GO:1990606	membrane scission GTPase motor activity	7/1277	40/18639	0.175	2.55428739232576	0.0177285003884074	0.104239860643479
GO:0042171	lysophosphatidic acid acyltransferase activity	5/1277	23/18639	0.217391304347826	3.17302781655374	0.0178642605296026	0.104239860643479
GO:0071617	lysophospholipid acyltransferase activity	5/1277	23/18639	0.217391304347826	3.17302781655374	0.0178642605296026	0.104239860643479
GO:0016829	lyase activity	22/1277	200/18639	0.11	1.60555207517619	0.0189771124325937	0.110147578510875
GO:0032813	tumor necrosis factor receptor superfamily binding	8/1277	50/18639	0.16	2.33534847298356	0.0194622628462598	0.112368959696563
GO:0001530	lipopolysaccharide binding	7/1277	41/18639	0.170731707317073	2.49198769983001	0.0201521677478154	0.115743078635358
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/1277	16/18639	0.25	3.6489819890368	0.0205322670442135	0.116704129261669
GO:0016722	oxidoreductase activity, acting on metal ions	4/1277	16/18639	0.25	3.6489819890368	0.0205322670442135	0.116704129261669
GO:0072341	modified amino acid binding	12/1277	91/18639	0.131868131868132	1.92473775245897	0.021217058116179	0.119974808007466
GO:0015171	amino acid transmembrane transporter activity	13/1277	102/18639	0.127450980392157	1.86026532774425	0.0219052889883763	0.123231292411532
GO:0015026	coreceptor activity	9/1277	61/18639	0.147540983606557	2.15349756730041	0.0223680732099191	0.125192736282047
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/1277	33/18639	0.181818181818182	2.65380508293586	0.0229524744517926	0.127811494789932
GO:0019838	growth factor binding	16/1277	136/18639	0.117647058823529	1.71716799484085	0.0238278180359265	0.13201573932026
GO:0005518	collagen binding	10/1277	72/18639	0.138888888888889	2.02721221613156	0.0244229679966864	0.133959979461825
GO:0042379	chemokine receptor binding	10/1277	72/18639	0.138888888888889	2.02721221613156	0.0244229679966864	0.133959979461825
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/1277	17/18639	0.235294117647059	3.4343359896817	0.0254271223138852	0.137406665903114
GO:0016805	dipeptidase activity	4/1277	17/18639	0.235294117647059	3.4343359896817	0.0254271223138852	0.137406665903114
GO:0070402	NADPH binding	4/1277	17/18639	0.235294117647059	3.4343359896817	0.0254271223138852	0.137406665903114
GO:0005345	purine nucleobase transmembrane transporter activity	3/1277	10/18639	0.3	4.37877838684417	0.026749594903074	0.141759930476677
GO:0008239	dipeptidyl-peptidase activity	3/1277	10/18639	0.3	4.37877838684417	0.026749594903074	0.141759930476677
GO:0030957	Tat protein binding	3/1277	10/18639	0.3	4.37877838684417	0.026749594903074	0.141759930476677
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/1277	10/18639	0.3	4.37877838684417	0.026749594903074	0.141759930476677
GO:0017171	serine hydrolase activity	21/1277	198/18639	0.106060606060606	1.54805296504592	0.0306715825234515	0.161763105904934
GO:0015172	acidic amino acid transmembrane transporter activity	4/1277	18/18639	0.222222222222222	3.24353954581049	0.0309645601725243	0.162526901958178
GO:0031406	carboxylic acid binding	20/1277	187/18639	0.106951871657754	1.56106181349168	0.0317741291548869	0.165981998490052
GO:0160215	deacylase activity	9/1277	65/18639	0.138461538461538	2.02097464008192	0.0323873367021686	0.168383451953929
GO:0016409	palmitoyltransferase activity	6/1277	36/18639	0.166666666666667	2.43265465935787	0.0339493325358315	0.171418700968279
GO:0008199	ferric iron binding	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0008526	phosphatidylinositol transfer activity	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0015173	aromatic amino acid transmembrane transporter activity	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0015205	nucleobase transmembrane transporter activity	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0019107	myristoyltransferase activity	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0019206	nucleoside kinase activity	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0019864	IgG binding	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0032050	clathrin heavy chain binding	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0050786	RAGE receptor binding	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0097493	structural molecule activity conferring elasticity	3/1277	11/18639	0.272727272727273	3.98070762440379	0.0349435740850766	0.171418700968279
GO:0043177	organic acid binding	20/1277	189/18639	0.105820105820106	1.54454264086214	0.0350025424037325	0.171418700968279
GO:0030170	pyridoxal phosphate binding	8/1277	56/18639	0.142857142857143	2.08513256516389	0.035997309157015	0.174730301527635
GO:0170055	lipid transmembrane transporter activity	8/1277	56/18639	0.142857142857143	2.08513256516389	0.035997309157015	0.174730301527635
GO:0031420	alkali metal ion binding	4/1277	19/18639	0.210526315789474	3.07282693813626	0.0371552140775779	0.177214216709143
GO:0043395	heparan sulfate proteoglycan binding	4/1277	19/18639	0.210526315789474	3.07282693813626	0.0371552140775779	0.177214216709143
GO:0070003	threonine-type peptidase activity	4/1277	19/18639	0.210526315789474	3.07282693813626	0.0371552140775779	0.177214216709143
GO:0097001	ceramide binding	4/1277	19/18639	0.210526315789474	3.07282693813626	0.0371552140775779	0.177214216709143
GO:0015291	secondary active transmembrane transporter activity	28/1277	287/18639	0.0975609756097561	1.42399297133144	0.0375344093508849	0.178247822761562
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	9/1277	67/18639	0.134328358208955	1.96064703888545	0.0384101289787168	0.180840821844002
GO:0050840	extracellular matrix binding	9/1277	67/18639	0.134328358208955	1.96064703888545	0.0384101289787168	0.180840821844002
GO:0070279	vitamin B6 binding	8/1277	57/18639	0.140350877192982	2.04855129209084	0.0394598859153123	0.184989294226913
GO:0016853	isomerase activity	19/1277	180/18639	0.105555555555556	1.54068128425998	0.0399770437389246	0.186300985855071
GO:1902936	phosphatidylinositol bisphosphate binding	13/1277	111/18639	0.117117117117117	1.7094330038731	0.0402041156666093	0.186300985855071
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	11/1277	89/18639	0.123595505617978	1.80399109570359	0.0404189923732971	0.186300985855071
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	11/1277	89/18639	0.123595505617978	1.80399109570359	0.0404189923732971	0.186300985855071
GO:0030145	manganese ion binding	9/1277	68/18639	0.132352941176471	1.93181399419596	0.0416895374134122	0.191353232395453
GO:0042887	amide transmembrane transporter activity	6/1277	38/18639	0.157894736842105	2.30462020360219	0.0428968546546893	0.195758692191741
GO:0140793	histone H2AXY142 phosphatase activity	11/1277	90/18639	0.122222222222222	1.78394675019577	0.0433180996631906	0.195758692191741
GO:0140693	molecular condensate scaffold activity	7/1277	48/18639	0.145833333333333	2.12857282693814	0.0437570063873009	0.195758692191741
GO:0016408	C-acyltransferase activity	4/1277	20/18639	0.2	2.91918559122944	0.0440040197721549	0.195758692191741
GO:0008236	serine-type peptidase activity	20/1277	194/18639	0.103092783505155	1.50473484083992	0.0441280464865887	0.195758692191741
GO:0015368	calcium:monoatomic cation antiporter activity	3/1277	12/18639	0.25	3.6489819890368	0.0442735043094055	0.195758692191741
GO:0016208	AMP binding	3/1277	12/18639	0.25	3.6489819890368	0.0442735043094055	0.195758692191741
GO:0016801	hydrolase activity, acting on ether bonds	3/1277	12/18639	0.25	3.6489819890368	0.0442735043094055	0.195758692191741
GO:0016803	ether hydrolase activity	3/1277	12/18639	0.25	3.6489819890368	0.0442735043094055	0.195758692191741
GO:0015085	calcium ion transmembrane transporter activity	16/1277	147/18639	0.108843537414966	1.58867243060106	0.0444338325941143	0.195758692191741
GO:0051861	glycolipid binding	5/1277	29/18639	0.172413793103448	2.516539302784	0.0449934452118015	0.197431237589385
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/1277	39/18639	0.153846153846154	2.2455273778688	0.0478749369226204	0.209238270135915
GO:0001846	opsonin binding	4/1277	21/18639	0.19047619047619	2.78017675355185	0.0515105443266505	0.223348091408441
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/1277	21/18639	0.19047619047619	2.78017675355185	0.0515105443266505	0.223348091408441
GO:0005096	GTPase activator activity	26/1277	271/18639	0.0959409594095941	1.40034733158608	0.0517142724105048	0.223348648954031
GO:0048020	CCR chemokine receptor binding	7/1277	50/18639	0.14	2.04342991386061	0.052828009025032	0.227061483475405
GO:0015036	disulfide oxidoreductase activity	6/1277	40/18639	0.15	2.18938919342208	0.053194896311011	0.227061483475405
GO:0050997	quaternary ammonium group binding	6/1277	40/18639	0.15	2.18938919342208	0.053194896311011	0.227061483475405
GO:0032396	inhibitory MHC class I receptor activity	3/1277	13/18639	0.230769230769231	3.3682910668032	0.0547036720776633	0.229923096816845
GO:0035673	oligopeptide transmembrane transporter activity	3/1277	13/18639	0.230769230769231	3.3682910668032	0.0547036720776633	0.229923096816845
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/1277	13/18639	0.230769230769231	3.3682910668032	0.0547036720776633	0.229923096816845
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/1277	13/18639	0.230769230769231	3.3682910668032	0.0547036720776633	0.229923096816845
GO:0030695	GTPase regulator activity	43/1277	489/18639	0.0879345603271984	1.28348650739127	0.0551880340143253	0.230615671228592
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	8/1277	61/18639	0.131147540983607	1.91422005982259	0.0554991223376009	0.230615671228592
GO:0016836	hydro-lyase activity	8/1277	61/18639	0.131147540983607	1.91422005982259	0.0554991223376009	0.230615671228592
GO:0060589	nucleoside-triphosphatase regulator activity	43/1277	490/18639	0.0877551020408163	1.2808671471721	0.0566564348129139	0.234536260338742
GO:0016878	acid-thiol ligase activity	5/1277	31/18639	0.161290322580645	2.35418192841084	0.0575883059320335	0.237497637621958
GO:0035591	signaling adaptor activity	14/1277	129/18639	0.108527131782946	1.58405419679117	0.0585044537446032	0.240032425200661
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/1277	41/18639	0.146341463414634	2.13598945699715	0.0588593640647017	0.240032425200661
GO:0140828	metal cation:monoatomic cation antiporter activity	6/1277	41/18639	0.146341463414634	2.13598945699715	0.0588593640647017	0.240032425200661
GO:1901682	sulfur compound transmembrane transporter activity	8/1277	63/18639	0.126984126984127	1.85345116903457	0.064875069614366	0.263585005062813
GO:0004065	arylsulfatase activity	3/1277	14/18639	0.214285714285714	3.12769884774583	0.0661871093280978	0.264026396119721
GO:0008191	metalloendopeptidase inhibitor activity	3/1277	14/18639	0.214285714285714	3.12769884774583	0.0661871093280978	0.264026396119721
GO:0008474	palmitoyl-(protein) hydrolase activity	3/1277	14/18639	0.214285714285714	3.12769884774583	0.0661871093280978	0.264026396119721
GO:0071933	Arp2/3 complex binding	3/1277	14/18639	0.214285714285714	3.12769884774583	0.0661871093280978	0.264026396119721
GO:0098599	palmitoyl hydrolase activity	3/1277	14/18639	0.214285714285714	3.12769884774583	0.0661871093280978	0.264026396119721
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/1277	23/18639	0.173913043478261	2.53842225324299	0.0684704302951609	0.271162678822352
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/1277	23/18639	0.173913043478261	2.53842225324299	0.0684704302951609	0.271162678822352
GO:0008375	acetylglucosaminyltransferase activity	6/1277	43/18639	0.13953488372093	2.03664111016008	0.0712259284054455	0.281060587988395
GO:0004725	protein tyrosine phosphatase activity	11/1277	98/18639	0.112244897959184	1.63831844405734	0.0717171779355554	0.281179216172061
GO:0019956	chemokine binding	5/1277	33/18639	0.151515151515152	2.21150423577988	0.0719991511808035	0.281179216172061
GO:0008194	UDP-glycosyltransferase activity	15/1277	145/18639	0.103448275862069	1.5099235816704	0.0720249405144476	0.281179216172061
GO:0051536	iron-sulfur cluster binding	9/1277	76/18639	0.118421052631579	1.72846515270164	0.0747545455849337	0.290800484066214
GO:0005315	phosphate transmembrane transporter activity	4/1277	24/18639	0.166666666666667	2.43265465935787	0.0778995536540358	0.296559581668655
GO:0050431	transforming growth factor beta binding	4/1277	24/18639	0.166666666666667	2.43265465935787	0.0778995536540358	0.296559581668655
GO:0060229	lipase activator activity	4/1277	24/18639	0.166666666666667	2.43265465935787	0.0778995536540358	0.296559581668655
GO:0019205	nucleobase-containing compound kinase activity	6/1277	44/18639	0.136363636363636	1.99035381220189	0.0779269211367225	0.296559581668655
GO:0000774	adenyl-nucleotide exchange factor activity	3/1277	15/18639	0.2	2.91918559122944	0.0786680385283307	0.296559581668655
GO:0004129	cytochrome-c oxidase activity	3/1277	15/18639	0.2	2.91918559122944	0.0786680385283307	0.296559581668655
GO:0016846	carbon-sulfur lyase activity	3/1277	15/18639	0.2	2.91918559122944	0.0786680385283307	0.296559581668655
GO:0047372	monoacylglycerol lipase activity	3/1277	15/18639	0.2	2.91918559122944	0.0786680385283307	0.296559581668655
GO:0050780	dopamine receptor binding	3/1277	15/18639	0.2	2.91918559122944	0.0786680385283307	0.296559581668655
GO:0051540	metal cluster binding	9/1277	77/18639	0.116883116883117	1.70601755331591	0.0797704687259994	0.299685630795963
GO:0043130	ubiquitin binding	11/1277	100/18639	0.11	1.60555207517619	0.0803224262644227	0.299733004860828
GO:0098632	cell-cell adhesion mediator activity	7/1277	55/18639	0.127272727272727	1.8576635580551	0.0803295382215892	0.299733004860828
GO:0141110	transporter inhibitor activity	6/1277	45/18639	0.133333333333333	1.9461237274863	0.084970270142	0.315974191002624
GO:0001848	complement binding	4/1277	25/18639	0.16	2.33534847298356	0.0879387605786885	0.321430303538481
GO:0015645	fatty acid ligase activity	4/1277	25/18639	0.16	2.33534847298356	0.0879387605786885	0.321430303538481
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/1277	25/18639	0.16	2.33534847298356	0.0879387605786885	0.321430303538481
GO:0019707	protein-cysteine S-acyltransferase activity	4/1277	25/18639	0.16	2.33534847298356	0.0879387605786885	0.321430303538481
GO:0120515	fatty acid-CoA ligase activity	4/1277	25/18639	0.16	2.33534847298356	0.0879387605786885	0.321430303538481
GO:0061631	ubiquitin conjugating enzyme activity	5/1277	35/18639	0.142857142857143	2.08513256516389	0.0881955527484801	0.321430303538481
GO:1901681	sulfur compound binding	25/1277	275/18639	0.0909090909090909	1.32690254146793	0.0905198196422631	0.327974455895792
GO:0004721	phosphoprotein phosphatase activity	17/1277	175/18639	0.0971428571428571	1.41789014431144	0.092023564750592	0.327974455895792
GO:0005149	interleukin-1 receptor binding	3/1277	16/18639	0.1875	2.7367364917776	0.0920839857938961	0.327974455895792
GO:0015923	mannosidase activity	3/1277	16/18639	0.1875	2.7367364917776	0.0920839857938961	0.327974455895792
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/1277	16/18639	0.1875	2.7367364917776	0.0920839857938961	0.327974455895792
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/1277	16/18639	0.1875	2.7367364917776	0.0920839857938961	0.327974455895792
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/1277	16/18639	0.1875	2.7367364917776	0.0920839857938961	0.327974455895792
GO:0070851	growth factor receptor binding	14/1277	139/18639	0.100719424460432	1.47009346320907	0.0948085409470702	0.336585661549955
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/1277	36/18639	0.138888888888889	2.02721221613156	0.0969449431053588	0.342176348300016
GO:0046906	tetrapyrrole binding	15/1277	152/18639	0.0986842105263158	1.44038762725137	0.0981725387286146	0.342176348300016
GO:0052689	carboxylic ester hydrolase activity	10/1277	92/18639	0.108695652173913	1.58651390827687	0.0982162798775784	0.342176348300016
GO:0008198	ferrous iron binding	4/1277	26/18639	0.153846153846154	2.2455273778688	0.0985667511967228	0.342176348300016
GO:0019865	immunoglobulin binding	4/1277	26/18639	0.153846153846154	2.2455273778688	0.0985667511967228	0.342176348300016
GO:0030247	polysaccharide binding	4/1277	26/18639	0.153846153846154	2.2455273778688	0.0985667511967228	0.342176348300016
GO:0051139	metal cation:proton antiporter activity	4/1277	26/18639	0.153846153846154	2.2455273778688	0.0985667511967228	0.342176348300016
GO:0001784	phosphotyrosine residue binding	6/1277	47/18639	0.127659574468085	1.86330995184858	0.100068624680086	0.346294262694178
GO:0016757	glycosyltransferase activity	24/1277	267/18639	0.0898876404494382	1.31199352414806	0.104940177957533	0.362010613897529
GO:0046873	metal ion transmembrane transporter activity	38/1277	450/18639	0.0844444444444444	1.23254502740799	0.106178200951027	0.362376573100127
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1277	17/18639	0.176470588235294	2.57575199226127	0.106367599396756	0.362376573100127
GO:0019198	transmembrane receptor protein phosphatase activity	3/1277	17/18639	0.176470588235294	2.57575199226127	0.106367599396756	0.362376573100127
GO:0070492	oligosaccharide binding	3/1277	17/18639	0.176470588235294	2.57575199226127	0.106367599396756	0.362376573100127
GO:0020037	heme binding	14/1277	142/18639	0.0985915492957746	1.43903515060606	0.107934163752531	0.365975572101733
GO:0016298	lipase activity	13/1277	130/18639	0.1	1.45959279561472	0.108990529505532	0.365975572101733
GO:0005085	guanyl-nucleotide exchange factor activity	21/1277	230/18639	0.091304347826087	1.33267168295257	0.109398273358648	0.365975572101733
GO:0001671	ATPase activator activity	4/1277	27/18639	0.148148148148148	2.162359697207	0.109759310138077	0.365975572101733
GO:0008320	protein transmembrane transporter activity	4/1277	27/18639	0.148148148148148	2.162359697207	0.109759310138077	0.365975572101733
GO:0016405	CoA-ligase activity	4/1277	27/18639	0.148148148148148	2.162359697207	0.109759310138077	0.365975572101733
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/1277	27/18639	0.148148148148148	2.162359697207	0.109759310138077	0.365975572101733
GO:0031072	heat shock protein binding	13/1277	131/18639	0.099236641221374	1.44845086587721	0.11385203770839	0.378471773836678
GO:0000146	microfilament motor activity	5/1277	38/18639	0.131578947368421	1.92051683633516	0.115693480649805	0.382276350219387
GO:0043531	ADP binding	5/1277	38/18639	0.131578947368421	1.92051683633516	0.115693480649805	0.382276350219387
GO:0016763	pentosyltransferase activity	6/1277	49/18639	0.122448979591837	1.78725648442619	0.116479142093342	0.382567721186814
GO:0035254	glutamate receptor binding	6/1277	49/18639	0.122448979591837	1.78725648442619	0.116479142093342	0.382567721186814
GO:0005516	calmodulin binding	19/1277	207/18639	0.0917874396135266	1.33972285587825	0.118525250512932	0.386302071880361
GO:0051117	ATPase binding	9/1277	84/18639	0.107142857142857	1.56384942387292	0.120423257721368	0.386302071880361
GO:0004706	JUN kinase kinase kinase activity	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:0008525	phosphatidylcholine transporter activity	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:0035615	clathrin adaptor activity	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:0050811	GABA receptor binding	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:0098641	cadherin binding involved in cell-cell adhesion	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:1990381	ubiquitin-specific protease binding	3/1277	18/18639	0.166666666666667	2.43265465935787	0.121448207241602	0.386302071880361
GO:0046625	sphingolipid binding	4/1277	28/18639	0.142857142857143	2.08513256516389	0.121489712669758	0.386302071880361
GO:0050698	proteoglycan sulfotransferase activity	4/1277	28/18639	0.142857142857143	2.08513256516389	0.121489712669758	0.386302071880361
GO:0051087	protein-folding chaperone binding	13/1277	134/18639	0.0970149253731343	1.41602286141727	0.129181959697647	0.409574016729244
GO:0004222	metalloendopeptidase activity	11/1277	110/18639	0.1	1.45959279561472	0.132572958866086	0.419113936242352
GO:0005416	amino acid:monoatomic cation symporter activity	4/1277	29/18639	0.137931034482759	2.0132314422272	0.133729115463031	0.420346245452565
GO:0016417	S-acyltransferase activity	4/1277	29/18639	0.137931034482759	2.0132314422272	0.133729115463031	0.420346245452565
GO:0016830	carbon-carbon lyase activity	6/1277	51/18639	0.117647058823529	1.71716799484085	0.134143548901401	0.420444208985249
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/1277	40/18639	0.125	1.8244909945184	0.136019924417059	0.421755457634348
GO:0003756	protein disulfide isomerase activity	3/1277	19/18639	0.157894736842105	2.30462020360219	0.137253143459856	0.421755457634348
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/1277	19/18639	0.157894736842105	2.30462020360219	0.137253143459856	0.421755457634348
GO:0005520	insulin-like growth factor binding	3/1277	19/18639	0.157894736842105	2.30462020360219	0.137253143459856	0.421755457634348
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/1277	19/18639	0.157894736842105	2.30462020360219	0.137253143459856	0.421755457634348
GO:0030506	ankyrin binding	3/1277	19/18639	0.157894736842105	2.30462020360219	0.137253143459856	0.421755457634348
GO:0034987	immunoglobulin receptor binding	3/1277	19/18639	0.157894736842105	2.30462020360219	0.137253143459856	0.421755457634348
GO:0005507	copper ion binding	7/1277	63/18639	0.111111111111111	1.62176977290525	0.138508551211572	0.424424247706967
GO:0140789	histone phosphatase activity	13/1277	136/18639	0.0955882352941176	1.39519899580819	0.140014000319482	0.426976460994044
GO:0044183	protein folding chaperone	8/1277	75/18639	0.106666666666667	1.55689898198904	0.140404244127064	0.426976460994044
GO:0008234	cysteine-type peptidase activity	17/1277	187/18639	0.0909090909090909	1.32690254146793	0.142301384558711	0.426976460994044
GO:0001965	G-protein alpha-subunit binding	4/1277	30/18639	0.133333333333333	1.9461237274863	0.146446929005342	0.426976460994044
GO:0016769	transferase activity, transferring nitrogenous groups	4/1277	30/18639	0.133333333333333	1.9461237274863	0.146446929005342	0.426976460994044
GO:0051721	protein phosphatase 2A binding	4/1277	30/18639	0.133333333333333	1.9461237274863	0.146446929005342	0.426976460994044
GO:0070566	adenylyltransferase activity	4/1277	30/18639	0.133333333333333	1.9461237274863	0.146446929005342	0.426976460994044
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0005522	profilin binding	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0008140	cAMP response element binding protein binding	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0016868	intramolecular phosphotransferase activity	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0035256	G protein-coupled glutamate receptor binding	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0043422	protein kinase B binding	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0071723	lipopeptide binding	2/1277	10/18639	0.2	2.91918559122944	0.146471664065056	0.426976460994044
GO:0042169	SH2 domain binding	5/1277	41/18639	0.121951219512195	1.7799912141643	0.146736668910442	0.426976460994044
GO:0061650	ubiquitin-like protein conjugating enzyme activity	5/1277	41/18639	0.121951219512195	1.7799912141643	0.146736668910442	0.426976460994044
GO:0019842	vitamin binding	14/1277	150/18639	0.0933333333333333	1.36228660924041	0.147949938469254	0.428749679858304
GO:0098631	cell adhesion mediator activity	8/1277	76/18639	0.105263157894737	1.53641346906813	0.148127738073197	0.428749679858304
GO:0004252	serine-type endopeptidase activity	16/1277	176/18639	0.0909090909090909	1.32690254146793	0.15102338143945	0.435707058586273
GO:0005544	calcium-dependent phospholipid binding	6/1277	53/18639	0.113207547169811	1.6523692025827	0.152989056891041	0.435707058586273
GO:0001614	purinergic nucleotide receptor activity	3/1277	20/18639	0.15	2.18938919342208	0.153708871169451	0.435707058586273
GO:0001972	retinoic acid binding	3/1277	20/18639	0.15	2.18938919342208	0.153708871169451	0.435707058586273
GO:0010851	cyclase regulator activity	3/1277	20/18639	0.15	2.18938919342208	0.153708871169451	0.435707058586273
GO:0016004	phospholipase activator activity	3/1277	20/18639	0.15	2.18938919342208	0.153708871169451	0.435707058586273
GO:0016502	nucleotide receptor activity	3/1277	20/18639	0.15	2.18938919342208	0.153708871169451	0.435707058586273
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/1277	20/18639	0.15	2.18938919342208	0.153708871169451	0.435707058586273
GO:0016859	cis-trans isomerase activity	5/1277	42/18639	0.119047619047619	1.73761047096991	0.157799774967743	0.445003478508006
GO:0048487	beta-tubulin binding	5/1277	42/18639	0.119047619047619	1.73761047096991	0.157799774967743	0.445003478508006
GO:0070325	lipoprotein particle receptor binding	4/1277	31/18639	0.129032258064516	1.88334554272867	0.159611169460646	0.448957571534177
GO:0003774	cytoskeletal motor activity	14/1277	153/18639	0.0915032679738562	1.33557510709844	0.164772298456546	0.462289543239976
GO:0008200	ion channel inhibitor activity	5/1277	43/18639	0.116279069767442	1.6972009251334	0.169191070568046	0.467332053269864
GO:0005506	iron ion binding	14/1277	154/18639	0.0909090909090909	1.32690254146793	0.170589706636853	0.467332053269864
GO:0051010	microtubule plus-end binding	3/1277	21/18639	0.142857142857143	2.08513256516389	0.170741925643251	0.467332053269864
GO:0140312	cargo adaptor activity	3/1277	21/18639	0.142857142857143	2.08513256516389	0.170741925643251	0.467332053269864
GO:0000099	sulfur amino acid transmembrane transporter activity	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0001851	complement component C3b binding	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0008432	JUN kinase binding	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0010854	adenylate cyclase regulator activity	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0034713	type I transforming growth factor beta receptor binding	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0050998	nitric-oxide synthase binding	2/1277	11/18639	0.181818181818182	2.65380508293586	0.171255684060607	0.467332053269864
GO:0016835	carbon-oxygen lyase activity	8/1277	79/18639	0.10126582278481	1.47806865378706	0.172487970602745	0.469106422052496
GO:0043425	bHLH transcription factor binding	4/1277	32/18639	0.125	1.8244909945184	0.173188788451468	0.469106422052496
GO:0051059	NF-kappaB binding	4/1277	32/18639	0.125	1.8244909945184	0.173188788451468	0.469106422052496
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	12/1277	130/18639	0.0923076923076923	1.34731642672128	0.18012227284679	0.486367862728978
GO:0016248	channel inhibitor activity	5/1277	44/18639	0.113636363636364	1.65862817683491	0.18089160254642	0.486367862728978
GO:0030547	signaling receptor inhibitor activity	5/1277	44/18639	0.113636363636364	1.65862817683491	0.18089160254642	0.486367862728978
GO:0140416	transcription regulator inhibitor activity	4/1277	33/18639	0.121212121212121	1.76920338862391	0.187145979799146	0.49821564815681
GO:0008093	cytoskeletal anchor activity	3/1277	22/18639	0.136363636363636	1.99035381220189	0.188279699593376	0.49821564815681
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/1277	22/18639	0.136363636363636	1.99035381220189	0.188279699593376	0.49821564815681
GO:0016881	acid-amino acid ligase activity	3/1277	22/18639	0.136363636363636	1.99035381220189	0.188279699593376	0.49821564815681
GO:0141108	transporter regulator activity	15/1277	170/18639	0.0882352941176471	1.28787599613064	0.188875761499328	0.49821564815681
GO:0008009	chemokine activity	5/1277	45/18639	0.111111111111111	1.62176977290525	0.192881769096973	0.49821564815681
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/1277	57/18639	0.105263157894737	1.53641346906813	0.193872139371193	0.49821564815681
GO:0016758	hexosyltransferase activity	17/1277	197/18639	0.0862944162436548	1.25954708251017	0.193911122475008	0.49821564815681
GO:0003995	acyl-CoA dehydrogenase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0004300	enoyl-CoA hydratase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0004875	complement receptor activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0005049	nuclear export signal receptor activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0008179	adenylate cyclase binding	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0010853	cyclase activator activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0016840	carbon-nitrogen lyase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0017166	vinculin binding	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0031543	peptidyl-proline dioxygenase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0042301	phosphate ion binding	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:1990459	transferrin receptor binding	2/1277	12/18639	0.166666666666667	2.43265465935787	0.196652120010847	0.49821564815681
GO:0032182	ubiquitin-like protein binding	11/1277	120/18639	0.0916666666666667	1.33796006264683	0.199326350739772	0.503827204519654
GO:0015035	protein-disulfide reductase activity	4/1277	34/18639	0.117647058823529	1.71716799484085	0.201448462728966	0.506855421132285
GO:0090482	vitamin transmembrane transporter activity	4/1277	34/18639	0.117647058823529	1.71716799484085	0.201448462728966	0.506855421132285
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/1277	46/18639	0.108695652173913	1.58651390827687	0.205141447572445	0.514221467538534
GO:0005283	amino acid:sodium symporter activity	3/1277	23/18639	0.130434782608696	1.90381668993225	0.206251089988108	0.514221467538534
GO:0016493	C-C chemokine receptor activity	3/1277	23/18639	0.130434782608696	1.90381668993225	0.206251089988108	0.514221467538534
GO:0016849	phosphorus-oxygen lyase activity	3/1277	23/18639	0.130434782608696	1.90381668993225	0.206251089988108	0.514221467538534
GO:0004620	phospholipase activity	10/1277	109/18639	0.0917431192660551	1.33907595927956	0.213058187202169	0.529988279729658
GO:0015297	antiporter activity	12/1277	135/18639	0.0888888888888889	1.2974158183242	0.214645968603793	0.532729926602626
GO:0004879	nuclear receptor activity	6/1277	59/18639	0.101694915254237	1.48433165655734	0.215710513177965	0.532960434586098
GO:0045309	protein phosphorylated amino acid binding	6/1277	59/18639	0.101694915254237	1.48433165655734	0.215710513177965	0.532960434586098
GO:0004860	protein kinase inhibitor activity	8/1277	84/18639	0.0952380952380952	1.39008837677593	0.216686148190704	0.534143575637447
GO:0043495	protein-membrane adaptor activity	5/1277	47/18639	0.106382978723404	1.55275829320715	0.217650116964393	0.534143575637447
GO:0140359	ABC-type transporter activity	5/1277	47/18639	0.106382978723404	1.55275829320715	0.217650116964393	0.534143575637447
GO:0016779	nucleotidyltransferase activity	12/1277	136/18639	0.0882352941176471	1.28787599613064	0.221868417147436	0.535174646518399
GO:0005539	glycosaminoglycan binding	20/1277	242/18639	0.0826446280991736	1.20627503769812	0.222391404613632	0.535174646518399
GO:0005172	vascular endothelial growth factor receptor binding	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0031994	insulin-like growth factor I binding	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0071714	icosanoid transmembrane transporter activity	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0089720	caspase binding	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0140852	histone ubiquitin ligase activity	2/1277	13/18639	0.153846153846154	2.2455273778688	0.222460928725971	0.535174646518399
GO:0004622	lysophospholipase activity	3/1277	24/18639	0.125	1.8244909945184	0.224587023750119	0.535591228378001
GO:0019957	C-C chemokine binding	3/1277	24/18639	0.125	1.8244909945184	0.224587023750119	0.535591228378001
GO:0030215	semaphorin receptor binding	3/1277	24/18639	0.125	1.8244909945184	0.224587023750119	0.535591228378001
GO:0050699	WW domain binding	3/1277	24/18639	0.125	1.8244909945184	0.224587023750119	0.535591228378001
GO:0098531	ligand-modulated transcription factor activity	6/1277	60/18639	0.1	1.45959279561472	0.226931851636715	0.540009200098648
GO:0016879	ligase activity, forming carbon-nitrogen bonds	5/1277	48/18639	0.104166666666667	1.52040916209867	0.230386974567339	0.547044396321149
GO:0004190	aspartic-type endopeptidase activity	4/1277	36/18639	0.111111111111111	1.62176977290525	0.230951341227472	0.547200046061633
GO:0050660	flavin adenine dinucleotide binding	8/1277	86/18639	0.0930232558139535	1.35776074010672	0.235462540651796	0.556686222187543
GO:0003707	nuclear steroid receptor activity	3/1277	25/18639	0.12	1.75151135473767	0.24322087781895	0.569126726775855
GO:0004709	MAP kinase kinase kinase activity	3/1277	25/18639	0.12	1.75151135473767	0.24322087781895	0.569126726775855
GO:0008483	transaminase activity	3/1277	25/18639	0.12	1.75151135473767	0.24322087781895	0.569126726775855
GO:0070001	aspartic-type peptidase activity	4/1277	37/18639	0.108108108108108	1.57793815742132	0.246083021712087	0.569126726775855
GO:0004705	JUN kinase activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0005313	L-glutamate transmembrane transporter activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0005347	ATP transmembrane transporter activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0005545	1-phosphatidylinositol binding	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0019763	immunoglobulin receptor activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0019992	diacylglycerol binding	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0031404	chloride ion binding	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0061665	SUMO ligase activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:1901474	azole transmembrane transporter activity	2/1277	14/18639	0.142857142857143	2.08513256516389	0.248506565292283	0.569126726775855
GO:0015605	organophosphate ester transmembrane transporter activity	5/1277	50/18639	0.1	1.45959279561472	0.256461291370738	0.58612090965354
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/1277	128/18639	0.0859375	1.2543375587314	0.261370790787638	0.587957917574792
GO:0005501	retinoid binding	4/1277	38/18639	0.105263157894737	1.53641346906813	0.261422967719414	0.587957917574792
GO:0019840	isoprenoid binding	4/1277	38/18639	0.105263157894737	1.53641346906813	0.261422967719414	0.587957917574792
GO:0001637	G protein-coupled chemoattractant receptor activity	3/1277	26/18639	0.115384615384615	1.6841455334016	0.262088807378371	0.587957917574792
GO:0004950	chemokine receptor activity	3/1277	26/18639	0.115384615384615	1.6841455334016	0.262088807378371	0.587957917574792
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/1277	26/18639	0.115384615384615	1.6841455334016	0.262088807378371	0.587957917574792
GO:0043548	phosphatidylinositol 3-kinase binding	3/1277	26/18639	0.115384615384615	1.6841455334016	0.262088807378371	0.587957917574792
GO:0050750	low-density lipoprotein particle receptor binding	3/1277	26/18639	0.115384615384615	1.6841455334016	0.262088807378371	0.587957917574792
GO:0120014	phospholipid transfer activity	3/1277	26/18639	0.115384615384615	1.6841455334016	0.262088807378371	0.587957917574792
GO:0015294	solute:monoatomic cation symporter activity	10/1277	116/18639	0.0862068965517241	1.258269651392	0.271694084655215	0.607409717021302
GO:0004722	protein serine/threonine phosphatase activity	9/1277	103/18639	0.087378640776699	1.27537234568277	0.273426662414159	0.607409717021302
GO:0019210	kinase inhibitor activity	8/1277	90/18639	0.0888888888888889	1.2974158183242	0.274556024663263	0.607409717021302
GO:0004559	alpha-mannosidase activity	2/1277	15/18639	0.133333333333333	1.9461237274863	0.274635569409814	0.607409717021302
GO:0005523	tropomyosin binding	2/1277	15/18639	0.133333333333333	1.9461237274863	0.274635569409814	0.607409717021302
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/1277	15/18639	0.133333333333333	1.9461237274863	0.274635569409814	0.607409717021302
GO:0140776	protein-containing complex destabilizing activity	2/1277	15/18639	0.133333333333333	1.9461237274863	0.274635569409814	0.607409717021302
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4/1277	39/18639	0.102564102564103	1.49701825191254	0.276937958784056	0.611269498563599
GO:1990782	protein tyrosine kinase binding	10/1277	117/18639	0.0854700854700855	1.24751520992711	0.280459161347986	0.617798594374982
GO:0035255	ionotropic glutamate receptor binding	3/1277	27/18639	0.111111111111111	1.62176977290525	0.281129994533408	0.618035278563425
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	27/1277	349/18639	0.0773638968481375	1.12919786480222	0.282884395009712	0.620092663802813
GO:0030159	signaling receptor complex adaptor activity	5/1277	52/18639	0.0961538461538462	1.403454611168	0.283196376084968	0.620092663802813
GO:0005262	calcium channel activity	11/1277	131/18639	0.083969465648855	1.22561227112687	0.286167361706433	0.625349792414256
GO:0008201	heparin binding	14/1277	172/18639	0.0813953488372093	1.18804064759338	0.290672561197323	0.633932007223584
GO:0071949	FAD binding	4/1277	40/18639	0.1	1.45959279561472	0.292595518158167	0.636859689324422
GO:0015293	symporter activity	12/1277	146/18639	0.0821917808219178	1.19966531146416	0.298903621191688	0.644304024755756
GO:0051019	mitogen-activated protein kinase binding	3/1277	28/18639	0.107142857142857	1.56384942387292	0.300286828357046	0.644304024755756
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/1277	28/18639	0.107142857142857	1.56384942387292	0.300286828357046	0.644304024755756
GO:0001664	G protein-coupled receptor binding	23/1277	297/18639	0.0774410774410774	1.13032438717638	0.300710692939763	0.644304024755756
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/1277	16/18639	0.125	1.8244909945184	0.300714367069231	0.644304024755756
GO:0004707	MAP kinase activity	2/1277	16/18639	0.125	1.8244909945184	0.300714367069231	0.644304024755756
GO:0008142	oxysterol binding	2/1277	16/18639	0.125	1.8244909945184	0.300714367069231	0.644304024755756
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/1277	16/18639	0.125	1.8244909945184	0.300714367069231	0.644304024755756
GO:0099106	ion channel regulator activity	13/1277	160/18639	0.08125	1.18591914643696	0.302477271100814	0.646817868221429
GO:0051219	phosphoprotein binding	8/1277	93/18639	0.0860215053763441	1.25556369515245	0.304965178683577	0.650869262676818
GO:0017080	sodium channel regulator activity	4/1277	41/18639	0.0975609756097561	1.42399297133144	0.308364042401164	0.656845348571023
GO:0000287	magnesium ion binding	18/1277	230/18639	0.0782608695652174	1.14229001395935	0.313298694181633	0.663820101364647
GO:0019209	kinase activator activity	12/1277	148/18639	0.0810810810810811	1.18345361806599	0.315161424878481	0.663820101364647
GO:0030971	receptor tyrosine kinase binding	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0033192	calmodulin-dependent protein phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0140791	histone H2AXS140 phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:1990439	MAP kinase serine/threonine phosphatase activity	7/1277	81/18639	0.0864197530864197	1.26137649003741	0.318933604234949	0.663820101364647
GO:0003785	actin monomer binding	3/1277	29/18639	0.103448275862069	1.5099235816704	0.319505025998663	0.663820101364647
GO:0106222	lncRNA binding	3/1277	29/18639	0.103448275862069	1.5099235816704	0.319505025998663	0.663820101364647
GO:0005548	phospholipid transporter activity	6/1277	68/18639	0.0882352941176471	1.28787599613064	0.322066675982355	0.664768301595251
GO:0016791	phosphatase activity	21/1277	273/18639	0.0769230769230769	1.1227636889344	0.322507853106879	0.664768301595251
GO:0019894	kinesin binding	4/1277	42/18639	0.0952380952380952	1.39008837677593	0.324212912657313	0.664768301595251
GO:0042056	chemoattractant activity	4/1277	42/18639	0.0952380952380952	1.39008837677593	0.324212912657313	0.664768301595251
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0005092	GDP-dissociation inhibitor activity	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0016018	cyclosporin A binding	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0038191	neuropilin binding	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0051787	misfolded protein binding	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0070403	NAD+ binding	2/1277	17/18639	0.117647058823529	1.71716799484085	0.326627269425561	0.664768301595251
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	7/1277	82/18639	0.0853658536585366	1.24599384991501	0.330173390819126	0.669501311882776
GO:0033549	MAP kinase phosphatase activity	7/1277	82/18639	0.0853658536585366	1.24599384991501	0.330173390819126	0.669501311882776
GO:0016407	acetyltransferase activity	8/1277	96/18639	0.0833333333333333	1.21632732967893	0.336055372619041	0.680171113954037
GO:0015215	nucleotide transmembrane transporter activity	3/1277	30/18639	0.1	1.45959279561472	0.338733703442366	0.682319162498301
GO:0048019	receptor antagonist activity	3/1277	30/18639	0.1	1.45959279561472	0.338733703442366	0.682319162498301
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/1277	43/18639	0.0930232558139535	1.35776074010672	0.340112588769033	0.682319162498301
GO:0048156	tau protein binding	4/1277	43/18639	0.0930232558139535	1.35776074010672	0.340112588769033	0.682319162498301
GO:0008017	microtubule binding	21/1277	276/18639	0.0760869565217391	1.11055973579381	0.340799111427612	0.682319162498301
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	7/1277	83/18639	0.0843373493975904	1.23098187581965	0.341470574486388	0.682319162498301
GO:0030165	PDZ domain binding	7/1277	83/18639	0.0843373493975904	1.23098187581965	0.341470574486388	0.682319162498301
GO:0140297	DNA-binding transcription factor binding	36/1277	488/18639	0.0737704918032787	1.0767487836502	0.345943074054898	0.689999185887678
GO:0017018	myosin phosphatase activity	7/1277	84/18639	0.0833333333333333	1.21632732967893	0.352814613240541	0.702427641968917
GO:0140767	enzyme-substrate adaptor activity	11/1277	139/18639	0.079136690647482	1.15507343537856	0.355093306365585	0.705683617904069
GO:0042578	phosphoric ester hydrolase activity	27/1277	363/18639	0.0743801652892562	1.08564753392831	0.356629697994059	0.70619454613756
GO:0016874	ligase activity	13/1277	167/18639	0.0778443113772455	1.13620996065817	0.357791743433721	0.70619454613756
GO:0008327	methyl-CpG binding	3/1277	31/18639	0.0967741935483871	1.41250915704651	0.357925403511835	0.70619454613756
GO:0070273	phosphatidylinositol-4-phosphate binding	3/1277	31/18639	0.0967741935483871	1.41250915704651	0.357925403511835	0.70619454613756
GO:0016247	channel regulator activity	13/1277	168/18639	0.0773809523809524	1.12944680613044	0.365841468799687	0.720517219521107
GO:0051539	4 iron, 4 sulfur cluster binding	4/1277	45/18639	0.0888888888888889	1.2974158183242	0.371952045273667	0.731239056747693
GO:0042910	xenobiotic transmembrane transporter activity	3/1277	32/18639	0.09375	1.3683682458888	0.377036087828425	0.731794551966698
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0008381	mechanosensitive monoatomic ion channel activity	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0042834	peptidoglycan binding	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0046624	sphingolipid transporter activity	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0050145	nucleoside monophosphate kinase activity	2/1277	19/18639	0.105263157894737	1.53641346906813	0.377571300285461	0.731794551966698
GO:0015459	potassium channel regulator activity	5/1277	59/18639	0.0847457627118644	1.23694304713112	0.379619686577011	0.734467012654287
GO:0030296	protein tyrosine kinase activator activity	3/1277	33/18639	0.0909090909090909	1.32690254146793	0.396025098631353	0.764858333096117
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/1277	20/18639	0.1	1.45959279561472	0.402444903520574	0.773173483646357
GO:0015095	magnesium ion transmembrane transporter activity	2/1277	20/18639	0.1	1.45959279561472	0.402444903520574	0.773173483646357
GO:0031418	L-ascorbic acid binding	2/1277	20/18639	0.1	1.45959279561472	0.402444903520574	0.773173483646357
GO:0008376	acetylgalactosaminyltransferase activity	3/1277	34/18639	0.0882352941176471	1.28787599613064	0.414855095654165	0.794233926583977
GO:0016831	carboxy-lyase activity	3/1277	34/18639	0.0882352941176471	1.28787599613064	0.414855095654165	0.794233926583977
GO:0017022	myosin binding	6/1277	76/18639	0.0789473684210526	1.1523101018011	0.421584821278132	0.803152068027641
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0005123	death receptor binding	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0008373	sialyltransferase activity	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0009975	cyclase activity	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0015125	bile acid transmembrane transporter activity	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0015174	basic amino acid transmembrane transporter activity	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0019200	carbohydrate kinase activity	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0072542	protein phosphatase activator activity	2/1277	21/18639	0.0952380952380952	1.39008837677593	0.426834690665556	0.803152068027641
GO:0005154	epidermal growth factor receptor binding	3/1277	35/18639	0.0857142857142857	1.25107953909833	0.433491972612106	0.812890075137573
GO:0005343	organic acid:sodium symporter activity	3/1277	35/18639	0.0857142857142857	1.25107953909833	0.433491972612106	0.812890075137573
GO:0005125	cytokine activity	17/1277	234/18639	0.0726495726495727	1.06038792843805	0.437247074798415	0.818532493265975
GO:0008970	phospholipase A1 activity	2/1277	22/18639	0.0909090909090909	1.32690254146793	0.450690189772774	0.835985697706458
GO:0031683	G-protein beta/gamma-subunit complex binding	2/1277	22/18639	0.0909090909090909	1.32690254146793	0.450690189772774	0.835985697706458
GO:0033691	sialic acid binding	2/1277	22/18639	0.0909090909090909	1.32690254146793	0.450690189772774	0.835985697706458
GO:0140035	ubiquitin-like protein reader activity	2/1277	22/18639	0.0909090909090909	1.32690254146793	0.450690189772774	0.835985697706458
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/1277	36/18639	0.0833333333333333	1.21632732967893	0.451904757283436	0.835985697706458
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/1277	36/18639	0.0833333333333333	1.21632732967893	0.451904757283436	0.835985697706458
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/1277	36/18639	0.0833333333333333	1.21632732967893	0.451904757283436	0.835985697706458
GO:0046332	SMAD binding	6/1277	79/18639	0.0759493670886076	1.1085514903403	0.458655695993598	0.847045957079085
GO:0042562	hormone binding	7/1277	94/18639	0.074468085106383	1.08693080524501	0.466635310902655	0.85429159317396
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0003887	DNA-directed DNA polymerase activity	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0005158	insulin receptor binding	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0008171	O-methyltransferase activity	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0017134	fibroblast growth factor binding	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0031681	G-protein beta-subunit binding	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0099186	structural constituent of postsynapse	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0140103	catalytic activity, acting on a glycoprotein	2/1277	23/18639	0.0869565217391304	1.2692111266215	0.47397010403798	0.85429159317396
GO:0004867	serine-type endopeptidase inhibitor activity	7/1277	95/18639	0.0736842105263158	1.07548942834769	0.477851611769582	0.85429159317396
GO:0015631	tubulin binding	27/1277	385/18639	0.0701298701298701	1.02361053198955	0.478774378210402	0.85429159317396
GO:0030295	protein kinase activator activity	10/1277	139/18639	0.0719424460431655	1.05006675943505	0.483818221839037	0.85429159317396
GO:0005246	calcium channel regulator activity	4/1277	53/18639	0.0754716981132075	1.10157946838847	0.496291825845285	0.85429159317396
GO:0008146	sulfotransferase activity	4/1277	53/18639	0.0754716981132075	1.10157946838847	0.496291825845285	0.85429159317396
GO:0004806	triacylglycerol lipase activity	2/1277	24/18639	0.0833333333333333	1.21632732967893	0.496641293155058	0.85429159317396
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1277	24/18639	0.0833333333333333	1.21632732967893	0.496641293155058	0.85429159317396
GO:0035035	histone acetyltransferase binding	2/1277	24/18639	0.0833333333333333	1.21632732967893	0.496641293155058	0.85429159317396
GO:0070300	phosphatidic acid binding	2/1277	24/18639	0.0833333333333333	1.21632732967893	0.496641293155058	0.85429159317396
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1277	24/18639	0.0833333333333333	1.21632732967893	0.496641293155058	0.85429159317396
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/1277	39/18639	0.0769230769230769	1.1227636889344	0.505533409614872	0.85429159317396
GO:0003796	lysozyme activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0004382	GDP phosphatase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0004955	prostaglandin receptor activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0005031	tumor necrosis factor receptor activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0005337	nucleoside transmembrane transporter activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0005528	FK506 binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0015187	glycine transmembrane transporter activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0015203	polyamine transmembrane transporter activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0031419	cobalamin binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0031996	thioesterase binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0032052	bile acid binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0033204	ribonuclease P RNA binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0043121	neurotrophin binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0043208	glycosphingolipid binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0043295	glutathione binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0047429	nucleoside triphosphate diphosphatase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0050308	sugar-phosphatase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0070513	death domain binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0070739	protein-glutamic acid ligase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0070740	tubulin-glutamic acid ligase activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0098505	G-rich strand telomeric DNA binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0141109	transporter activator activity	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:1990763	arrestin family protein binding	1/1277	10/18639	0.1	1.45959279561472	0.508306702072201	0.85429159317396
GO:0008139	nuclear localization sequence binding	2/1277	25/18639	0.08	1.16767423649178	0.518677851010372	0.85429159317396
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1277	25/18639	0.08	1.16767423649178	0.518677851010372	0.85429159317396
GO:0017025	TBP-class protein binding	2/1277	25/18639	0.08	1.16767423649178	0.518677851010372	0.85429159317396
GO:0019211	phosphatase activator activity	2/1277	25/18639	0.08	1.16767423649178	0.518677851010372	0.85429159317396
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1277	25/18639	0.08	1.16767423649178	0.518677851010372	0.85429159317396
GO:0015144	carbohydrate transmembrane transporter activity	3/1277	40/18639	0.075	1.09469459671104	0.522798644057307	0.85429159317396
GO:0140662	ATP-dependent protein folding chaperone	3/1277	40/18639	0.075	1.09469459671104	0.522798644057307	0.85429159317396
GO:0097110	scaffold protein binding	5/1277	70/18639	0.0714285714285714	1.04256628258194	0.528401349676726	0.85429159317396
GO:0019903	protein phosphatase binding	10/1277	144/18639	0.0694444444444444	1.01360610806578	0.529480250185864	0.85429159317396
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/1277	41/18639	0.0731707317073171	1.06799472849858	0.539727691556477	0.85429159317396
GO:0005160	transforming growth factor beta receptor binding	2/1277	26/18639	0.0769230769230769	1.1227636889344	0.540060271313038	0.85429159317396
GO:0015216	purine nucleotide transmembrane transporter activity	2/1277	26/18639	0.0769230769230769	1.1227636889344	0.540060271313038	0.85429159317396
GO:0030507	spectrin binding	2/1277	26/18639	0.0769230769230769	1.1227636889344	0.540060271313038	0.85429159317396
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0002162	dystroglycan binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0003953	NAD+ nucleosidase activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0004016	adenylate cyclase activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0004954	prostanoid receptor activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0005114	type II transforming growth factor beta receptor binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0005225	volume-sensitive anion channel activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0005536	D-glucose binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0008271	secondary active sulfate transmembrane transporter activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0008503	benzodiazepine receptor activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0015217	ADP transmembrane transporter activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0019203	carbohydrate phosphatase activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0019215	intermediate filament binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0031731	CCR6 chemokine receptor binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0032794	GTPase activating protein binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0034056	estrogen response element binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0043522	leucine zipper domain binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0045294	alpha-catenin binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0048185	activin binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0070697	activin receptor binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0140031	phosphorylation-dependent protein binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0140537	transcription regulator activator activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0180030	inositol phosphate kinase activity	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:1900750	oligopeptide binding	1/1277	11/18639	0.0909090909090909	1.32690254146793	0.54201180387336	0.85429159317396
GO:0019902	phosphatase binding	13/1277	190/18639	0.068421052631579	0.998668754894284	0.54333726786567	0.855152055736929
GO:0004520	DNA endonuclease activity	3/1277	42/18639	0.0714285714285714	1.04256628258194	0.556305751471797	0.871810584806516
GO:0008307	structural constituent of muscle	3/1277	42/18639	0.0714285714285714	1.04256628258194	0.556305751471797	0.871810584806516
GO:0051879	Hsp90 protein binding	3/1277	42/18639	0.0714285714285714	1.04256628258194	0.556305751471797	0.871810584806516
GO:0043021	ribonucleoprotein complex binding	12/1277	177/18639	0.0677966101694915	0.989554437704896	0.557951138041468	0.872439290195059
GO:0008395	steroid hydroxylase activity	2/1277	27/18639	0.0740740740740741	1.0811798486035	0.560774693455409	0.872439290195059
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/1277	27/18639	0.0740740740740741	1.0811798486035	0.560774693455409	0.872439290195059
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/1277	27/18639	0.0740740740740741	1.0811798486035	0.560774693455409	0.872439290195059
GO:0043539	protein serine/threonine kinase activator activity	5/1277	73/18639	0.0684931506849315	0.999721092886796	0.566340709033299	0.872439290195059
GO:0004032	aldose reductase (NADPH) activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0004526	ribonuclease P activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0005095	GTPase inhibitor activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0005247	voltage-gated chloride channel activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0005527	macrolide binding	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0008504	monoamine transmembrane transporter activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0015132	prostaglandin transmembrane transporter activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0015166	polyol transmembrane transporter activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0015269	calcium-activated potassium channel activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0016423	tRNA (guanine) methyltransferase activity	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0035197	siRNA binding	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0035259	nuclear glucocorticoid receptor binding	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0035497	cAMP response element binding	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0043047	single-stranded telomeric DNA binding	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0070410	co-SMAD binding	1/1277	12/18639	0.0833333333333333	1.21632732967893	0.573408138769952	0.872439290195059
GO:0016866	intramolecular transferase activity	2/1277	28/18639	0.0714285714285714	1.04256628258194	0.580812221539898	0.877618466982463
GO:0019789	SUMO transferase activity	2/1277	28/18639	0.0714285714285714	1.04256628258194	0.580812221539898	0.877618466982463
GO:0045499	chemorepellent activity	2/1277	28/18639	0.0714285714285714	1.04256628258194	0.580812221539898	0.877618466982463
GO:0046875	ephrin receptor binding	2/1277	28/18639	0.0714285714285714	1.04256628258194	0.580812221539898	0.877618466982463
GO:0051959	dynein light intermediate chain binding	2/1277	28/18639	0.0714285714285714	1.04256628258194	0.580812221539898	0.877618466982463
GO:0070888	E-box binding	4/1277	59/18639	0.0677966101694915	0.989554437704896	0.582214842842859	0.878041294202594
GO:0019887	protein kinase regulator activity	17/1277	255/18639	0.0666666666666667	0.973061863743148	0.58269285522287	0.878041294202594
GO:0001046	core promoter sequence-specific DNA binding	3/1277	44/18639	0.0681818181818182	0.995176906100947	0.588360644865959	0.880307792741445
GO:0003954	NADH dehydrogenase activity	3/1277	44/18639	0.0681818181818182	0.995176906100947	0.588360644865959	0.880307792741445
GO:0051082	unfolded protein binding	8/1277	121/18639	0.0661157024793388	0.965020030158494	0.593453752710391	0.880307792741445
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/1277	60/18639	0.0666666666666667	0.973061863743148	0.595694445985612	0.880307792741445
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/1277	60/18639	0.0666666666666667	0.973061863743148	0.595694445985612	0.880307792741445
GO:0019207	kinase regulator activity	19/1277	287/18639	0.0662020905923345	0.966280944832046	0.595975956000135	0.880307792741445
GO:0004629	phospholipase C activity	2/1277	29/18639	0.0689655172413793	1.0066157211136	0.600168310098508	0.880307792741445
GO:0035250	UDP-galactosyltransferase activity	2/1277	29/18639	0.0689655172413793	1.0066157211136	0.600168310098508	0.880307792741445
GO:0099604	ligand-gated calcium channel activity	2/1277	29/18639	0.0689655172413793	1.0066157211136	0.600168310098508	0.880307792741445
GO:0004465	lipoprotein lipase activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0005035	death receptor activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0005542	folic acid binding	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0019104	DNA N-glycosylase activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0019855	calcium channel inhibitor activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0031432	titin binding	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0045159	myosin II binding	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0051011	microtubule minus-end binding	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0061459	L-arginine transmembrane transporter activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0070700	BMP receptor binding	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1277	13/18639	0.0769230769230769	1.1227636889344	0.602653739606951	0.880307792741445
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/1277	45/18639	0.0666666666666667	0.973061863743148	0.603818401979694	0.880836152887931
GO:0005201	extracellular matrix structural constituent	11/1277	168/18639	0.0654761904761905	0.955685759033449	0.606251673724233	0.883211269688557
GO:0033612	receptor serine/threonine kinase binding	2/1277	30/18639	0.0666666666666667	0.973061863743148	0.618842210573947	0.895072183216214
GO:0098918	structural constituent of synapse	2/1277	30/18639	0.0666666666666667	0.973061863743148	0.618842210573947	0.895072183216214
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/1277	46/18639	0.0652173913043478	0.951908344966123	0.61888674847612	0.895072183216214
GO:0030276	clathrin binding	3/1277	46/18639	0.0652173913043478	0.951908344966123	0.61888674847612	0.895072183216214
GO:0030291	protein serine/threonine kinase inhibitor activity	3/1277	46/18639	0.0652173913043478	0.951908344966123	0.61888674847612	0.895072183216214
GO:0051213	dioxygenase activity	6/1277	93/18639	0.0645161290322581	0.941672771364337	0.619844832328158	0.895072183216214
GO:0004713	protein tyrosine kinase activity	9/1277	140/18639	0.0642857142857143	0.93830965432375	0.627003982391986	0.895072183216214
GO:0008174	mRNA methyltransferase activity	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0008494	translation activator activity	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0008559	ABC-type xenobiotic transporter activity	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0015926	glucosidase activity	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0016530	metallochaperone activity	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0032036	myosin heavy chain binding	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0042043	neurexin family protein binding	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0043176	amine binding	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0061783	peptidoglycan muralytic activity	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0070742	C2H2 zinc finger domain binding	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0098847	sequence-specific single stranded DNA binding	1/1277	14/18639	0.0714285714285714	1.04256628258194	0.629895829938849	0.895072183216214
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1277	31/18639	0.0645161290322581	0.941672771364337	0.636836473129955	0.901431756159433
GO:0005452	solute:inorganic anion antiporter activity	2/1277	31/18639	0.0645161290322581	0.941672771364337	0.636836473129955	0.901431756159433
GO:0047499	calcium-independent phospholipase A2 activity	2/1277	31/18639	0.0645161290322581	0.941672771364337	0.636836473129955	0.901431756159433
GO:0140597	protein carrier chaperone	12/1277	188/18639	0.0638297872340425	0.931654975924291	0.64249692248637	0.906472767249251
GO:0004536	DNA nuclease activity	4/1277	64/18639	0.0625	0.912245497259201	0.64692897266182	0.906472767249251
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1277	48/18639	0.0625	0.912245497259201	0.647836419244121	0.906472767249251
GO:0008378	galactosyltransferase activity	2/1277	32/18639	0.0625	0.912245497259201	0.654156498816723	0.906472767249251
GO:0140142	nucleocytoplasmic carrier activity	2/1277	32/18639	0.0625	0.912245497259201	0.654156498816723	0.906472767249251
GO:0004089	carbonate dehydratase activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0004953	icosanoid receptor activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0008242	omega peptidase activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0010181	FMN binding	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0015116	sulfate transmembrane transporter activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0015250	water channel activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0033130	acetylcholine receptor binding	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0034483	heparan sulfate sulfotransferase activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0042809	nuclear vitamin D receptor binding	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0051371	muscle alpha-actinin binding	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0061578	K63-linked deubiquitinase activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0140161	monocarboxylate:sodium symporter activity	1/1277	15/18639	0.0666666666666667	0.973061863743148	0.65527156283378	0.906472767249251
GO:0001222	transcription corepressor binding	3/1277	49/18639	0.0612244897959184	0.893628242213095	0.661712102479883	0.914229441335556
GO:0019239	deaminase activity	2/1277	33/18639	0.0606060606060606	0.884601694311953	0.67081013753836	0.919695013282414
GO:0071889	14-3-3 protein binding	2/1277	33/18639	0.0606060606060606	0.884601694311953	0.67081013753836	0.919695013282414
GO:0005159	insulin-like growth factor receptor binding	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0005521	lamin binding	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0015378	sodium:chloride symporter activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0015385	sodium:proton antiporter activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0015562	efflux transmembrane transporter activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0019841	retinol binding	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0022841	potassium ion leak channel activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0030275	LRR domain binding	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0070411	I-SMAD binding	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0140327	flippase activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0140328	floppase activity	1/1277	16/18639	0.0625	0.912245497259201	0.678908709218083	0.919695013282414
GO:0008083	growth factor activity	10/1277	162/18639	0.0617283950617284	0.900983207169581	0.679082006161126	0.919695013282414
GO:0001221	transcription coregulator binding	7/1277	115/18639	0.0608695652173913	0.888447788635048	0.680755922304696	0.92082521179809
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/1277	34/18639	0.0588235294117647	0.858583997420425	0.686807327656122	0.925272557100637
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1277	34/18639	0.0588235294117647	0.858583997420425	0.686807327656122	0.925272557100637
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/1277	34/18639	0.0588235294117647	0.858583997420425	0.686807327656122	0.925272557100637
GO:0005021	vascular endothelial growth factor receptor activity	3/1277	51/18639	0.0588235294117647	0.858583997420425	0.688261081671941	0.925272557100637
GO:0005048	signal sequence binding	3/1277	51/18639	0.0588235294117647	0.858583997420425	0.688261081671941	0.925272557100637
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0004549	tRNA-specific ribonuclease activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0004550	nucleoside diphosphate kinase activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0004659	prenyltransferase activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0015278	intracellularly gated calcium channel activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0017110	nucleoside diphosphate phosphatase activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0030548	acetylcholine receptor regulator activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0032183	SUMO binding	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0045125	bioactive lipid receptor activity	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0046965	nuclear retinoid X receptor binding	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:1990226	histone methyltransferase binding	1/1277	17/18639	0.0588235294117647	0.858583997420425	0.700926299205115	0.925804412785762
GO:0015103	inorganic anion transmembrane transporter activity	10/1277	165/18639	0.0606060606060606	0.884601694311953	0.701050437477836	0.925804412785762
GO:0004623	phospholipase A2 activity	2/1277	35/18639	0.0571428571428571	0.834053026065555	0.702159773416366	0.925804412785762
GO:0034061	DNA polymerase activity	2/1277	35/18639	0.0571428571428571	0.834053026065555	0.702159773416366	0.925804412785762
GO:0043015	gamma-tubulin binding	2/1277	35/18639	0.0571428571428571	0.834053026065555	0.702159773416366	0.925804412785762
GO:0002039	p53 binding	4/1277	69/18639	0.0579710144927536	0.846140751080998	0.704641655931615	0.927961460452559
GO:0016860	intramolecular oxidoreductase activity	3/1277	53/18639	0.0566037735849057	0.826184601291352	0.713214950460141	0.932172480471308
GO:0016782	transferase activity, transferring sulphur-containing groups	4/1277	70/18639	0.0571428571428571	0.834053026065555	0.715322886613729	0.932172480471308
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/1277	36/18639	0.0555555555555556	0.810884886452623	0.716880656718303	0.932172480471308
GO:0008081	phosphoric diester hydrolase activity	5/1277	87/18639	0.0574712643678161	0.838846434261335	0.719681823633168	0.932172480471308
GO:0003746	translation elongation factor activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0005372	water transmembrane transporter activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0008308	voltage-gated monoatomic anion channel activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0008409	5'-3' exonuclease activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0015373	monoatomic anion:sodium symporter activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0017075	syntaxin-1 binding	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0070064	proline-rich region binding	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0099602	neurotransmitter receptor regulator activity	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:1901611	phosphatidylglycerol binding	1/1277	18/18639	0.0555555555555556	0.810884886452623	0.721435219617266	0.932172480471308
GO:0004674	protein serine/threonine kinase activity	27/1277	433/18639	0.0623556581986143	0.910138694725115	0.723245557675686	0.933412207964973
GO:0140104	molecular carrier activity	15/1277	249/18639	0.0602409638554217	0.879272768442604	0.734152752866314	0.944617478428264
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	7/1277	122/18639	0.0573770491803279	0.837471276172382	0.738575597499906	0.944617478428264
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0008574	plus-end-directed microtubule motor activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0016918	retinal binding	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0022840	leak channel activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0022842	narrow pore channel activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0140036	ubiquitin-modified protein reader activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0141147	intracellularly calcium-gated channel activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:1990380	K48-linked deubiquitinase activity	1/1277	19/18639	0.0526315789473684	0.768206734534064	0.740538770691255	0.944617478428264
GO:0106310	protein serine kinase activity	22/1277	361/18639	0.0609418282548476	0.889502534723653	0.746770807871532	0.951460599576157
GO:0003714	transcription corepressor activity	12/1277	204/18639	0.0588235294117647	0.858583997420425	0.748329839896079	0.952340875134569
GO:0005326	neurotransmitter transmembrane transporter activity	1/1277	20/18639	0.05	0.729796397807361	0.75833318475287	0.961724281703929
GO:0030742	GTP-dependent protein binding	1/1277	20/18639	0.05	0.729796397807361	0.75833318475287	0.961724281703929
GO:0043024	ribosomal small subunit binding	1/1277	20/18639	0.05	0.729796397807361	0.75833318475287	0.961724281703929
GO:0036122	BMP binding	1/1277	21/18639	0.0476190476190476	0.695044188387963	0.774908109457236	0.978497890787038
GO:0070182	DNA polymerase binding	1/1277	21/18639	0.0476190476190476	0.695044188387963	0.774908109457236	0.978497890787038
GO:0004519	endonuclease activity	7/1277	127/18639	0.0551181102362205	0.804499966086855	0.775127317314436	0.978497890787038
GO:0042826	histone deacetylase binding	7/1277	127/18639	0.0551181102362205	0.804499966086855	0.775127317314436	0.978497890787038
GO:0031593	polyubiquitin modification-dependent protein binding	3/1277	59/18639	0.0508474576271186	0.742165828278672	0.778801205788196	0.982005658332932
GO:0016410	N-acyltransferase activity	5/1277	94/18639	0.0531914893617021	0.776379146603576	0.780120661999683	0.982080548793638
GO:0046982	protein heterodimerization activity	22/1277	369/18639	0.0596205962059621	0.870217926924767	0.781179194078335	0.982080548793638
GO:0001727	lipid kinase activity	2/1277	41/18639	0.0487804878048781	0.711996485665718	0.781546325521282	0.982080548793638
GO:0043022	ribosome binding	6/1277	112/18639	0.0535714285714286	0.781924711936458	0.787542910177847	0.985572894416729
GO:0015377	chloride:monoatomic cation symporter activity	1/1277	22/18639	0.0454545454545455	0.663451270733965	0.790347058013639	0.985572894416729
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/1277	22/18639	0.0454545454545455	0.663451270733965	0.790347058013639	0.985572894416729
GO:0050321	tau-protein kinase activity	1/1277	22/18639	0.0454545454545455	0.663451270733965	0.790347058013639	0.985572894416729
GO:0070034	telomerase RNA binding	1/1277	22/18639	0.0454545454545455	0.663451270733965	0.790347058013639	0.985572894416729
GO:0140517	protein-RNA adaptor activity	1/1277	22/18639	0.0454545454545455	0.663451270733965	0.790347058013639	0.985572894416729
GO:0019199	transmembrane receptor protein kinase activity	4/1277	78/18639	0.0512820512820513	0.748509125956268	0.790614536997923	0.985572894416729
GO:0031492	nucleosomal DNA binding	2/1277	42/18639	0.0476190476190476	0.695044188387963	0.792808354223756	0.987185884884745
GO:0005261	monoatomic cation channel activity	20/1277	341/18639	0.0586510263929619	0.856066155785761	0.795884773711843	0.989892966850217
GO:0015081	sodium ion transmembrane transporter activity	9/1277	164/18639	0.0548780487804878	0.800996046373933	0.798986770747941	0.992625693669865
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	10/1277	181/18639	0.0552486187845304	0.806404859455647	0.801619968950147	0.993385034680749
GO:0005245	voltage-gated calcium channel activity	2/1277	43/18639	0.0465116279069767	0.678880370053359	0.803554115957866	0.993385034680749
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1277	43/18639	0.0465116279069767	0.678880370053359	0.803554115957866	0.993385034680749
GO:0005212	structural constituent of eye lens	1/1277	23/18639	0.0434782608695652	0.634605563310749	0.804727828648896	0.993385034680749
GO:0043274	phospholipase binding	1/1277	23/18639	0.0434782608695652	0.634605563310749	0.804727828648896	0.993385034680749
GO:0035402	histone H3T11 kinase activity	14/1277	247/18639	0.0566801619433198	0.827299560267454	0.805031263291874	0.993385034680749
GO:0035401	histone H3Y41 kinase activity	6/1277	115/18639	0.0521739130434783	0.761526675972898	0.807988616456286	0.994796310047751
GO:0140801	histone H2AXY142 kinase activity	6/1277	115/18639	0.0521739130434783	0.761526675972898	0.807988616456286	0.994796310047751
GO:0004679	AMP-activated protein kinase activity	14/1277	248/18639	0.0564516129032258	0.823963674943795	0.809604731651988	0.995668599352276
GO:0001223	transcription coactivator binding	2/1277	44/18639	0.0454545454545455	0.663451270733965	0.813801424105099	0.997475041612619
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/1277	44/18639	0.0454545454545455	0.663451270733965	0.813801424105099	0.997475041612619
GO:0043014	alpha-tubulin binding	2/1277	44/18639	0.0454545454545455	0.663451270733965	0.813801424105099	0.997475041612619
GO:0005540	hyaluronic acid binding	1/1277	24/18639	0.0416666666666667	0.608163664839467	0.818122895409497	0.999421844392226
GO:0015149	hexose transmembrane transporter activity	1/1277	24/18639	0.0416666666666667	0.608163664839467	0.818122895409497	0.999421844392226
GO:0055056	D-glucose transmembrane transporter activity	1/1277	24/18639	0.0416666666666667	0.608163664839467	0.818122895409497	0.999421844392226
GO:0019208	phosphatase regulator activity	6/1277	117/18639	0.0512820512820513	0.748509125956268	0.82074384805392	0.9999999999417
GO:0140303	intramembrane lipid transporter activity	2/1277	45/18639	0.0444444444444444	0.648707909162099	0.823568076296979	0.9999999999417
GO:0015271	outward rectifier potassium channel activity	1/1277	25/18639	0.04	0.583837118245889	0.830599772259461	0.9999999999417
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1277	25/18639	0.04	0.583837118245889	0.830599772259461	0.9999999999417
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/1277	25/18639	0.04	0.583837118245889	0.830599772259461	0.9999999999417
GO:0017056	structural constituent of nuclear pore	1/1277	25/18639	0.04	0.583837118245889	0.830599772259461	0.9999999999417
GO:0042974	nuclear retinoic acid receptor binding	1/1277	25/18639	0.04	0.583837118245889	0.830599772259461	0.9999999999417
GO:0016922	nuclear receptor binding	7/1277	137/18639	0.0510948905109489	0.74577734082504	0.836636274084705	0.9999999999417
GO:0016887	ATP hydrolysis activity	24/1277	417/18639	0.0575539568345324	0.840053407548042	0.840041817232008	0.9999999999417
GO:0004435	phosphatidylinositol phospholipase C activity	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0004529	DNA exonuclease activity	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0005112	Notch binding	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0005227	calcium-activated cation channel activity	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0008157	protein phosphatase 1 binding	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0015145	monosaccharide transmembrane transporter activity	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0050681	nuclear androgen receptor binding	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0052742	phosphatidylinositol kinase activity	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0070412	R-SMAD binding	1/1277	26/18639	0.0384615384615385	0.561381844467201	0.842221352297318	0.9999999999417
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/1277	27/18639	0.037037037037037	0.540589924301749	0.853046223791238	0.9999999999417
GO:0005104	fibroblast growth factor receptor binding	1/1277	27/18639	0.037037037037037	0.540589924301749	0.853046223791238	0.9999999999417
GO:0008266	poly(U) RNA binding	1/1277	27/18639	0.037037037037037	0.540589924301749	0.853046223791238	0.9999999999417
GO:0015252	proton channel activity	1/1277	27/18639	0.037037037037037	0.540589924301749	0.853046223791238	0.9999999999417
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	13/1277	243/18639	0.0534979423868313	0.780852112880304	0.857114987094573	0.9999999999417
GO:0004497	monooxygenase activity	5/1277	106/18639	0.0471698113207547	0.688487167742793	0.859647142615946	0.9999999999417
GO:0008080	N-acetyltransferase activity	3/1277	69/18639	0.0434782608695652	0.634605563310749	0.860332749940144	0.9999999999417
GO:0008527	taste receptor activity	1/1277	28/18639	0.0357142857142857	0.521283141290972	0.863128964615361	0.9999999999417
GO:0046966	nuclear thyroid hormone receptor binding	1/1277	28/18639	0.0357142857142857	0.521283141290972	0.863128964615361	0.9999999999417
GO:0051119	sugar transmembrane transporter activity	1/1277	28/18639	0.0357142857142857	0.521283141290972	0.863128964615361	0.9999999999417
GO:0051393	alpha-actinin binding	1/1277	28/18639	0.0357142857142857	0.521283141290972	0.863128964615361	0.9999999999417
GO:0097718	disordered domain specific binding	1/1277	28/18639	0.0357142857142857	0.521283141290972	0.863128964615361	0.9999999999417
GO:0004676	3-phosphoinositide-dependent protein kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0004711	ribosomal protein S6 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0035175	histone H3S10 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0035979	histone H2AXS139 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0044022	histone H3S28 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0044023	histone H4S1 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0044024	histone H2AS1 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0044025	histone H2BS14 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0072354	histone H3T3 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0072371	histone H2AS121 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0072518	Rho-dependent protein serine/threonine kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0140823	histone H2BS36 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0140855	histone H3S57 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0140995	histone H2A kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0140997	histone H4 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0140998	histone H2B kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:1990244	histone H2AT120 kinase activity	13/1277	245/18639	0.0530612244897959	0.774477809918016	0.864498192240148	0.9999999999417
GO:0019888	protein phosphatase regulator activity	5/1277	107/18639	0.0467289719626168	0.682052708231178	0.865029205506288	0.9999999999417
GO:0003727	single-stranded RNA binding	4/1277	89/18639	0.0449438202247191	0.655996762074032	0.867102492675535	0.9999999999417
GO:0004677	DNA-dependent protein kinase activity	13/1277	246/18639	0.0528455284552846	0.771329526137861	0.868075656255972	0.9999999999417
GO:0140857	histone H3T45 kinase activity	13/1277	246/18639	0.0528455284552846	0.771329526137861	0.868075656255972	0.9999999999417
GO:0035403	histone H3T6 kinase activity	13/1277	247/18639	0.0526315789473684	0.768206734534064	0.871578122531755	0.9999999999417
GO:0004181	metallocarboxypeptidase activity	1/1277	29/18639	0.0344827586206897	0.503307860556801	0.872520416562392	0.9999999999417
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/1277	29/18639	0.0344827586206897	0.503307860556801	0.872520416562392	0.9999999999417
GO:0097472	cyclin-dependent protein kinase activity	1/1277	29/18639	0.0344827586206897	0.503307860556801	0.872520416562392	0.9999999999417
GO:0005010	insulin-like growth factor receptor activity	2/1277	51/18639	0.0392156862745098	0.572389331613616	0.873050605457879	0.9999999999417
GO:0005030	neurotrophin receptor activity	2/1277	51/18639	0.0392156862745098	0.572389331613616	0.873050605457879	0.9999999999417
GO:0030544	Hsp70 protein binding	2/1277	51/18639	0.0392156862745098	0.572389331613616	0.873050605457879	0.9999999999417
GO:0031490	chromatin DNA binding	6/1277	128/18639	0.046875	0.684184122944401	0.879274886914242	0.9999999999417
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/1277	30/18639	0.0333333333333333	0.486530931871574	0.881267940906821	0.9999999999417
GO:0008187	poly-pyrimidine tract binding	1/1277	30/18639	0.0333333333333333	0.486530931871574	0.881267940906821	0.9999999999417
GO:0022839	monoatomic ion-gated channel activity	1/1277	30/18639	0.0333333333333333	0.486530931871574	0.881267940906821	0.9999999999417
GO:0031624	ubiquitin conjugating enzyme binding	1/1277	30/18639	0.0333333333333333	0.486530931871574	0.881267940906821	0.9999999999417
GO:0035925	mRNA 3'-UTR AU-rich region binding	1/1277	30/18639	0.0333333333333333	0.486530931871574	0.881267940906821	0.9999999999417
GO:0004521	RNA endonuclease activity	3/1277	73/18639	0.0410958904109589	0.599832655732078	0.884733073276755	0.9999999999417
GO:0004864	protein phosphatase inhibitor activity	2/1277	53/18639	0.0377358490566038	0.550789734194235	0.88647322650777	0.9999999999417
GO:0034212	protein N-acetyltransferase activity	2/1277	53/18639	0.0377358490566038	0.550789734194235	0.88647322650777	0.9999999999417
GO:0038064	collagen receptor activity	2/1277	53/18639	0.0377358490566038	0.550789734194235	0.88647322650777	0.9999999999417
GO:0140296	general transcription initiation factor binding	2/1277	53/18639	0.0377358490566038	0.550789734194235	0.88647322650777	0.9999999999417
GO:0017147	Wnt-protein binding	1/1277	31/18639	0.032258064516129	0.470836385682168	0.889415656499383	0.9999999999417
GO:0072349	modified amino acid transmembrane transporter activity	1/1277	31/18639	0.032258064516129	0.470836385682168	0.889415656499383	0.9999999999417
GO:0061659	ubiquitin-like protein ligase activity	20/1277	372/18639	0.0537634408602151	0.784727309470281	0.896162416661657	0.9999999999417
GO:0015106	bicarbonate transmembrane transporter activity	1/1277	32/18639	0.03125	0.456122748629601	0.89700466158592	0.9999999999417
GO:0030515	snoRNA binding	1/1277	32/18639	0.03125	0.456122748629601	0.89700466158592	0.9999999999417
GO:0031369	translation initiation factor binding	1/1277	32/18639	0.03125	0.456122748629601	0.89700466158592	0.9999999999417
GO:0047498	calcium-dependent phospholipase A2 activity	1/1277	32/18639	0.03125	0.456122748629601	0.89700466158592	0.9999999999417
GO:0070717	poly-purine tract binding	1/1277	32/18639	0.03125	0.456122748629601	0.89700466158592	0.9999999999417
GO:0042923	neuropeptide binding	1/1277	33/18639	0.0303030303030303	0.442300847155976	0.904073240462407	0.9999999999417
GO:0019212	phosphatase inhibitor activity	2/1277	56/18639	0.0357142857142857	0.521283141290972	0.904157204524732	0.9999999999417
GO:0003724	RNA helicase activity	3/1277	77/18639	0.038961038961039	0.56867251777197	0.905255141113299	0.9999999999417
GO:0008175	tRNA methyltransferase activity	1/1277	34/18639	0.0294117647058824	0.429291998710212	0.910657056001991	0.9999999999417
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1277	34/18639	0.0294117647058824	0.429291998710212	0.910657056001991	0.9999999999417
GO:0019825	oxygen binding	1/1277	34/18639	0.0294117647058824	0.429291998710212	0.910657056001991	0.9999999999417
GO:0030332	cyclin binding	1/1277	34/18639	0.0294117647058824	0.429291998710212	0.910657056001991	0.9999999999417
GO:0051427	hormone receptor binding	1/1277	34/18639	0.0294117647058824	0.429291998710212	0.910657056001991	0.9999999999417
GO:0004518	nuclease activity	10/1277	209/18639	0.0478468899521531	0.698369758667331	0.9138684436688	0.9999999999417
GO:0008186	ATP-dependent activity, acting on RNA	3/1277	79/18639	0.0379746835443038	0.554275745170148	0.914224030290879	0.9999999999417
GO:0015370	solute:sodium symporter activity	3/1277	79/18639	0.0379746835443038	0.554275745170148	0.914224030290879	0.9999999999417
GO:0061980	regulatory RNA binding	2/1277	58/18639	0.0344827586206897	0.503307860556801	0.914479115943012	0.9999999999417
GO:0005216	monoatomic ion channel activity	24/1277	448/18639	0.0535714285714286	0.781924711936458	0.917428418432072	0.9999999999417
GO:0000049	tRNA binding	3/1277	80/18639	0.0375	0.547347298355521	0.918412454217572	0.9999999999417
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/1277	36/18639	0.0277777777777778	0.405442443226312	0.92250100537067	0.9999999999417
GO:0045505	dynein intermediate chain binding	1/1277	36/18639	0.0277777777777778	0.405442443226312	0.92250100537067	0.9999999999417
GO:0003697	single-stranded DNA binding	5/1277	121/18639	0.0413223140495868	0.603137518849059	0.923792314246151	0.9999999999417
GO:0015108	chloride transmembrane transporter activity	5/1277	121/18639	0.0413223140495868	0.603137518849059	0.923792314246151	0.9999999999417
GO:0061630	ubiquitin protein ligase activity	18/1277	353/18639	0.0509915014164306	0.74426828105	0.9276179740051	0.9999999999417
GO:0019213	deacetylase activity	1/1277	37/18639	0.027027027027027	0.39448453935533	0.927820911629964	0.9999999999417
GO:0022829	wide pore channel activity	1/1277	37/18639	0.027027027027027	0.39448453935533	0.927820911629964	0.9999999999417
GO:0042805	actinin binding	1/1277	37/18639	0.027027027027027	0.39448453935533	0.927820911629964	0.9999999999417
GO:0015079	potassium ion transmembrane transporter activity	7/1277	160/18639	0.04375	0.638571848081441	0.927830344755826	0.9999999999417
GO:0005253	monoatomic anion channel activity	4/1277	103/18639	0.0388349514563107	0.566832153636785	0.928745042704721	0.9999999999417
GO:0141003	histone H2AX kinase activity	18/1277	354/18639	0.0508474576271186	0.742165828278672	0.929498838019561	0.9999999999417
GO:0005254	chloride channel activity	3/1277	83/18639	0.036144578313253	0.527563661065562	0.929881248373159	0.9999999999417
GO:0005109	frizzled binding	1/1277	38/18639	0.0263157894736842	0.384103367267032	0.932775900117683	0.9999999999417
GO:0042162	telomeric DNA binding	1/1277	38/18639	0.0263157894736842	0.384103367267032	0.932775900117683	0.9999999999417
GO:0005267	potassium channel activity	5/1277	124/18639	0.0403225806451613	0.58854548210271	0.932942597656444	0.9999999999417
GO:0140996	histone H3 kinase activity	18/1277	357/18639	0.0504201680672269	0.735929140646078	0.93489703183862	0.9999999999417
GO:0000217	DNA secondary structure binding	1/1277	39/18639	0.0256410256410256	0.374254562978134	0.937390984013694	0.9999999999417
GO:0008013	beta-catenin binding	4/1277	106/18639	0.0377358490566038	0.550789734194235	0.938002029926791	0.9999999999417
GO:0140713	histone chaperone activity	7/1277	164/18639	0.0426829268292683	0.622996924957503	0.938033274013945	0.9999999999417
GO:0035173	histone kinase activity	18/1277	360/18639	0.05	0.729796397807361	0.939941984275902	0.9999999999417
GO:0016755	aminoacyltransferase activity	26/1277	496/18639	0.0524193548387097	0.765109126733524	0.94137645717919	0.9999999999417
GO:0008509	monoatomic anion transmembrane transporter activity	6/1277	149/18639	0.0402684563758389	0.587755488167002	0.947149944796436	0.9999999999417
GO:0035198	miRNA binding	1/1277	42/18639	0.0238095238095238	0.347522094193981	0.949421936488051	0.9999999999417
GO:0000510	H3-H4 histone complex chaperone activity	6/1277	151/18639	0.0397350993377483	0.579970647264128	0.951358557526353	0.9999999999417
GO:0140584	chromatin extrusion motor activity	6/1277	151/18639	0.0397350993377483	0.579970647264128	0.951358557526353	0.9999999999417
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	6/1277	151/18639	0.0397350993377483	0.579970647264128	0.951358557526353	0.9999999999417
GO:0140849	ATP-dependent H2AZ histone chaperone activity	6/1277	151/18639	0.0397350993377483	0.579970647264128	0.951358557526353	0.9999999999417
GO:0003777	microtubule motor activity	2/1277	68/18639	0.0294117647058824	0.429291998710212	0.952159967739684	0.9999999999417
GO:1990841	promoter-specific chromatin binding	2/1277	68/18639	0.0294117647058824	0.429291998710212	0.952159967739684	0.9999999999417
GO:0015616	DNA translocase activity	6/1277	152/18639	0.0394736842105263	0.576155050900548	0.953347495660962	0.9999999999417
GO:0140674	ATP-dependent histone chaperone activity	6/1277	152/18639	0.0394736842105263	0.576155050900548	0.953347495660962	0.9999999999417
GO:0061775	cohesin loader activity	6/1277	153/18639	0.0392156862745098	0.572389331613616	0.955262692166638	0.9999999999417
GO:0005244	voltage-gated monoatomic ion channel activity	7/1277	173/18639	0.0404624277456647	0.590586680306535	0.95646106910333	0.9999999999417
GO:0022832	voltage-gated channel activity	7/1277	175/18639	0.04	0.583837118245889	0.959817593330061	0.9999999999417
GO:0140299	molecular sensor activity	2/1277	71/18639	0.028169014084507	0.411152900173161	0.959939078915458	0.9999999999417
GO:0003712	transcription coregulator activity	25/1277	495/18639	0.0505050505050505	0.737168078593294	0.960116708727334	0.9999999999417
GO:0019787	ubiquitin-like protein transferase activity	24/1277	479/18639	0.0501043841336117	0.731319981101322	0.961128199384167	0.9999999999417
GO:0140658	ATP-dependent chromatin remodeler activity	6/1277	158/18639	0.0379746835443038	0.554275745170148	0.963811899423445	0.9999999999417
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/1277	73/18639	0.0273972602739726	0.399888437154718	0.964434734191865	0.9999999999417
GO:0061733	protein-lysine-acetyltransferase activity	1/1277	47/18639	0.0212765957446809	0.31055165864143	0.964561938332255	0.9999999999417
GO:0099095	ligand-gated monoatomic anion channel activity	1/1277	47/18639	0.0212765957446809	0.31055165864143	0.964561938332255	0.9999999999417
GO:0004842	ubiquitin-protein transferase activity	22/1277	449/18639	0.0489977728285078	0.715167962216568	0.965266731698789	0.9999999999417
GO:0031491	nucleosome binding	2/1277	74/18639	0.027027027027027	0.39448453935533	0.966496629620311	0.9999999999417
GO:0003689	DNA clamp loader activity	6/1277	160/18639	0.0375	0.547347298355521	0.966792643287607	0.9999999999417
GO:0003713	transcription coactivator activity	11/1277	256/18639	0.04296875	0.627168779365701	0.967549661181726	0.9999999999417
GO:0005004	GPI-linked ephrin receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0005008	hepatocyte growth factor receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0005009	insulin receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0005011	macrophage colony-stimulating factor receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0005020	stem cell factor receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0008288	boss receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0036332	placental growth factor receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0038062	protein tyrosine kinase collagen receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0060175	brain-derived neurotrophic factor receptor activity	1/1277	49/18639	0.0204081632653061	0.297876080737698	0.969263033270062	0.9999999999417
GO:0004540	RNA nuclease activity	4/1277	121/18639	0.0330578512396694	0.482510015079247	0.969854056305729	0.9999999999417
GO:0022843	voltage-gated monoatomic cation channel activity	5/1277	143/18639	0.034965034965035	0.510347131333819	0.971293516419592	0.9999999999417
GO:0001217	DNA-binding transcription repressor activity	12/1277	278/18639	0.0431654676258993	0.630040055661031	0.97133284499105	0.9999999999417
GO:0005006	epidermal growth factor receptor activity	1/1277	50/18639	0.02	0.291918559122944	0.971374442980343	0.9999999999417
GO:0005007	fibroblast growth factor receptor activity	1/1277	50/18639	0.02	0.291918559122944	0.971374442980343	0.9999999999417
GO:0005017	platelet-derived growth factor receptor activity	1/1277	50/18639	0.02	0.291918559122944	0.971374442980343	0.9999999999417
GO:0005019	platelet-derived growth factor beta-receptor activity	1/1277	50/18639	0.02	0.291918559122944	0.971374442980343	0.9999999999417
GO:0003743	translation initiation factor activity	1/1277	51/18639	0.0196078431372549	0.286194665806808	0.973340919730793	0.9999999999417
GO:0005272	sodium channel activity	1/1277	51/18639	0.0196078431372549	0.286194665806808	0.973340919730793	0.9999999999417
GO:0016597	amino acid binding	1/1277	51/18639	0.0196078431372549	0.286194665806808	0.973340919730793	0.9999999999417
GO:0022836	gated channel activity	14/1277	318/18639	0.0440251572327044	0.642588023226607	0.974441821113826	0.9999999999417
GO:0005003	ephrin receptor activity	1/1277	53/18639	0.0188679245283019	0.275394867097117	0.976878158285577	0.9999999999417
GO:0005005	transmembrane-ephrin receptor activity	1/1277	53/18639	0.0188679245283019	0.275394867097117	0.976878158285577	0.9999999999417
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/1277	53/18639	0.0188679245283019	0.275394867097117	0.976878158285577	0.9999999999417
GO:0140463	chromatin-protein adaptor activity	1/1277	54/18639	0.0185185185185185	0.270294962150874	0.978466805217102	0.9999999999417
GO:0001653	peptide receptor activity	4/1277	128/18639	0.03125	0.456122748629601	0.97874162820774	0.9999999999417
GO:0008135	translation factor activity, RNA binding	2/1277	83/18639	0.0240963855421687	0.351709107377041	0.980538772534363	0.9999999999417
GO:0180051	translation factor activity	2/1277	84/18639	0.0238095238095238	0.347522094193981	0.981689426159027	0.9999999999417
GO:0099094	ligand-gated monoatomic cation channel activity	4/1277	136/18639	0.0294117647058824	0.429291998710212	0.985862575336068	0.9999999999417
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1277	60/18639	0.0166666666666667	0.243265465935787	0.985952840021197	0.9999999999417
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	10/1277	268/18639	0.0373134328358209	0.54462417746818	0.989923253715548	0.9999999999417
GO:0008173	RNA methyltransferase activity	1/1277	67/18639	0.0149253731343284	0.217849670987272	0.991467621753958	0.9999999999417
GO:0016500	protein-hormone receptor activity	1/1277	67/18639	0.0149253731343284	0.217849670987272	0.991467621753958	0.9999999999417
GO:0008528	G protein-coupled peptide receptor activity	3/1277	122/18639	0.0245901639344262	0.358916261216735	0.991485706041999	0.9999999999417
GO:0030594	neurotransmitter receptor activity	2/1277	97/18639	0.0206185567010309	0.300946968167984	0.991784804037237	0.9999999999417
GO:0140223	general transcription initiation factor activity	1/1277	68/18639	0.0147058823529412	0.214645999355106	0.992054303157156	0.9999999999417
GO:0005249	voltage-gated potassium channel activity	2/1277	98/18639	0.0204081632653061	0.297876080737698	0.992280984807555	0.9999999999417
GO:0140097	catalytic activity, acting on DNA	13/1277	336/18639	0.0386904761904762	0.56472340306522	0.993045615935909	0.9999999999417
GO:0019783	ubiquitin-like protein peptidase activity	3/1277	127/18639	0.0236220472440945	0.344785699751509	0.993595988742635	0.9999999999417
GO:0001216	DNA-binding transcription activator activity	21/1277	491/18639	0.0427698574338086	0.624265757798557	0.994154700792575	0.9999999999417
GO:0004386	helicase activity	4/1277	155/18639	0.0258064516129032	0.376669108545735	0.994805943593962	0.9999999999417
GO:0005179	hormone activity	3/1277	132/18639	0.0227272727272727	0.331725635366982	0.995195608679026	0.9999999999417
GO:0004843	cysteine-type deubiquitinase activity	2/1277	108/18639	0.0185185185185185	0.270294962150874	0.995878215545346	0.9999999999417
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	20/1277	484/18639	0.0413223140495868	0.603137518849059	0.996007263468672	0.9999999999417
GO:0015276	ligand-gated monoatomic ion channel activity	5/1277	186/18639	0.0268817204301075	0.39236365473514	0.996529600436914	0.9999999999417
GO:0008094	ATP-dependent activity, acting on DNA	6/1277	210/18639	0.0285714285714286	0.417026513032778	0.996751918699651	0.9999999999417
GO:0140101	catalytic activity, acting on a tRNA	3/1277	139/18639	0.0215827338129496	0.315020027830516	0.996799958352737	0.9999999999417
GO:0022834	ligand-gated channel activity	5/1277	188/18639	0.0265957446808511	0.388189573301788	0.996870708989646	0.9999999999417
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/1277	167/18639	0.0239520958083832	0.349603064817897	0.997295777865282	0.9999999999417
GO:0101005	deubiquitinase activity	2/1277	115/18639	0.0173913043478261	0.253842225324299	0.997354744732757	0.9999999999417
GO:0004527	exonuclease activity	1/1277	84/18639	0.0119047619047619	0.173761047096991	0.997459686661275	0.9999999999417
GO:0140030	modification-dependent protein binding	4/1277	173/18639	0.023121387283237	0.337478103032306	0.998058785591955	0.9999999999417
GO:0008168	methyltransferase activity	5/1277	204/18639	0.0245098039215686	0.35774333225851	0.998650890536013	0.9999999999417
GO:0008276	protein methyltransferase activity	1/1277	95/18639	0.0105263157894737	0.153641346906813	0.998840823073846	0.9999999999417
GO:0008170	N-methyltransferase activity	1/1277	98/18639	0.0102040816326531	0.148938040368849	0.999064195902721	0.9999999999417
GO:0016741	transferase activity, transferring one-carbon groups	5/1277	215/18639	0.0232558139534884	0.33944018502668	0.9992531969948	0.9999999999417
GO:0042393	histone binding	6/1277	247/18639	0.0242914979757085	0.354556954400337	0.999509015025101	0.9999999999417
GO:0003735	structural constituent of ribosome	3/1277	175/18639	0.0171428571428571	0.250215907819667	0.999627747247236	0.9999999999417
GO:0140098	catalytic activity, acting on RNA	11/1277	387/18639	0.0284237726098191	0.414871337254831	0.999863947434105	0.9999999999417
GO:0003730	mRNA 3'-UTR binding	3/1277	262/18639	0.0114503816793893	0.167128946062754	0.999998452438526	0.9999999999417
GO:1903231	mRNA base-pairing translational repressor activity	1/1277	298/18639	0.00335570469798658	0.0489796240139168	0.999999999452855	0.9999999999417
GO:0045182	translation regulator activity	2/1277	356/18639	0.00561797752808989	0.081999595259254	0.999999999770763	0.9999999999417
GO:0030371	translation repressor activity	1/1277	329/18639	0.00303951367781155	0.0443645226630615	0.9999999999417	0.9999999999417