category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	52/416	250/9376	4.688	LGMN/CTSZ/PSAP/ASAH1/CD68/CTSD/CTSC/NPC2/CTSS/LAPTM5/TPP1/MCOLN1/CTSB/PLA2G15/MITF/HEXA/FUCA1/CLTC/TLR7/ACP5/LITAF/AP1S2/NPC1/RRAGD/DNASE2/CTBS/LAMP1/SLC15A3/GNS/ATP6V0A1/CTSL/CLCN7/VPS13C/GGA2/CTSO/M6PR/NAGLU/CTNS/TPCN1/GNPTG/SLC17A5/GPR155/SCARB2/CTSF/SLC11A2/ACP2/GGA1/LAMP2/ATP6V0D1/MANBA/CD63/PPT1	12.7350009935316
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	24/416	82/9376	6.59662288930582	LGMN/HLA-B/HLA-A/B2M/HSPA1A/HLA-E/HLA-DRA/HSPA1B/CTSS/CTSB/CD4/CD74/HLA-DPA1/HLA-DRB1/HSPA6/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F/CTSL/HSP90AA1/IFI30	10.9675578829523
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	30/416	155/9376	4.36228287841191	HLA-B/HLA-A/HLA-E/CD36/HLA-DRA/CTSS/NCF2/CD14/FCGR2A/HLA-DPA1/TLR4/STX7/ITGB5/HLA-DRB1/CYBA/HLA-DPB1/HLA-DQA2/COLEC12/HLA-C/HLA-DMB/HLA-DMA/HLA-F/LAMP1/ATP6V0A1/CTSL/NCF4/M6PR/MSR1/LAMP2/ATP6V0D1	9.09472110748842
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	14/416	44/9376	7.17132867132867	HLA-B/HLA-A/HLA-E/HLA-DRA/CD28/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F/ICA1	8.84088921481093
Human Diseases	Immune disease	hsa05330	Allograft rejection	13/416	39/9376	7.51282051282051	HLA-B/HLA-A/HLA-E/HLA-DRA/CD28/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F	8.78164814864571
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	27/416	180/9376	3.38076923076923	HLA-B/HLA-A/B2M/HLA-E/HLA-DRA/TNFRSF14/CD74/HLA-DPA1/BST2/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/TNFRSF1A/HLA-DMA/HLA-F/POU2F2/JAK2/BIRC3/OAS1/ZC3HAV1/IKBKB/PML/TRAF5/IFNAR1/SYK	6.94916095742265
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	13/416	45/9376	6.51111111111111	HLA-B/HLA-A/HLA-E/HLA-DRA/CD28/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F	7.98471883362717
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	19/416	99/9376	4.32556332556333	C1QA/C1QB/C2/HLA-DRA/FCGR2A/C1QC/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/HLA-DMA/ICAM1/FPR3/C5AR1/SELPLG/CFD/FPR1/PTAFR	7.16732899273234
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	16/416	78/9376	4.6232741617357	HLA-DRA/JUN/NCF2/FCGR2A/HLA-DPA1/TLR4/HLA-DRB1/CYBA/HLA-DPB1/HLA-DQA2/HLA-DMB/FOS/HLA-DMA/CR1/JAK2/NCF4	6.92360090587569
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	22/416	142/9376	3.49187432286024	TYROBP/CSF1R/JUN/LILRB5/NCF2/FCGR2A/JUNB/MITF/ACP5/CYBA/FOS/JUND/TNFRSF1A/SQSTM1/SIRPA/NFATC2/NCF4/FOSB/CYLD/IKBKB/IFNAR1/SYK	6.44694062932506
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	25/416	181/9376	3.11304717382065	CTSD/HLA-DRA/CTSS/CD14/CD74/FCGR2A/HLA-DPA1/TLR4/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/FCER1G/TNFRSF1A/HLA-DMA/CR1/LAMP1/IL10RA/ATP6V0A1/JAK2/TLR1/LAMP2/ATP6V0D1/IL18/SYK	6.1851596229189
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	19/416	112/9376	3.82348901098901	HSPA1A/HLA-DRA/HSPA1B/LY96/HLA-DPA1/TLR4/BIRC7/HLA-DRB1/HSPA6/HLA-DPB1/HLA-DQA2/HLA-DMB/TNFRSF1A/HLA-DMA/IL10RA/JAK2/BIRC3/IKBKB/STAT3	6.47700360281331
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	13/416	54/9376	5.42592592592593	HLA-B/HLA-A/HLA-E/HLA-DRA/CD28/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F	7.02788700770159
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	17/416	93/9376	4.11993382961125	MAF/HLA-DRA/JUN/RBPJ/CD4/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/FOS/HLA-DMA/JAK2/NFATC2/NOTCH2/STAT5A/IKBKB	6.51509842287357
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	17/416	95/9376	4.0331983805668	HLA-DRA/JUN/CD28/HLA-DPA1/TLR4/HLA-DRB1/ACP5/HLA-DPB1/HLA-DQA2/HLA-DMB/FOS/HLA-DMA/ATP6V0A1/CTSL/ICAM1/ATP6V0D1/IL18	6.40241071083541
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	18/416	109/9376	3.72194777699365	HLA-DRA/JUN/CD4/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/FOS/HLA-DMA/JAK2/IL6ST/NFATC2/HSP90AA1/STAT5A/RUNX1/IKBKB/STAT3	6.1588801759687
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	14/416	70/9376	4.50769230769231	HLA-B/HLA-A/HLA-E/HLA-DRA/CD28/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F/ICAM1	6.34698226728303
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	13/416	66/9376	4.43939393939394	MAF/HLA-DRA/JUN/HLA-DPA1/TLR4/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/HLA-DMA/TLR5/IL18/STAT3	6.04167483395097
Human Diseases	Immune disease	hsa05310	Asthma	9/416	32/9376	6.33894230769231	HLA-DRA/PRG2/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/FCER1G/HLA-DMA	6.51841641344392
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	25/416	216/9376	2.60861823361823	ABCA1/HSPA1A/CD36/HSPA1B/LY96/JUN/NCF2/CD14/TLR4/ABCG1/HSPA6/CYBA/FOS/TNFRSF1A/POU2F2/JAK2/ICAM1/NFE2L2/NFATC2/NCF4/HSP90AA1/IL18/VAV1/IKBKB/STAT3	5.15359664236652
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	24/416	205/9376	2.63864915572233	HLA-B/HLA-A/B2M/HLA-E/HLA-DRA/JUN/GADD45B/RBPJ/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F/BCL2L11/ICAM1/OAS1/IKBKB/TRAF5/IFNAR1/SYK/STAT3	5.11131752539511
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	19/416	142/9376	3.01570964247021	KLF2/JUN/DUSP1/NCF2/HMOX1/GSTT1/CYBA/FOS/TNFRSF1A/PDGFB/MEF2C/SQSTM1/CTSL/ICAM1/NFE2L2/HSP90AA1/MGST2/MEF2A/IKBKB	5.21501436559099
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	25/416	224/9376	2.5154532967033	HLA-B/HLA-A/B2M/HLA-E/HLA-DRA/JUN/CD4/NRP1/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/PRKACB/HLA-DMB/FOS/TNFRSF1A/HLA-DMA/HLA-F/ADCY7/ICAM1/NFATC2/STAT5A/ATM/IKBKB	4.94637295500833
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	20/416	160/9376	2.81730769230769	HLA-B/HLA-A/HLA-E/HLA-DRA/CD28/SIGLEC1/CD4/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-C/HLA-DMB/HLA-DMA/HLA-F/ICAM1/PTPRM/SELPLG/CD99/CADM1	4.99569046926684
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	15/416	100/9376	3.38076923076923	CD37/CD36/CSF1R/HLA-DRA/CD4/CD14/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/HLA-DMA/CD59/CR1/EPOR	5.15721491199474
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	18/416	137/9376	2.96125772038181	CTSZ/CTSD/CTSC/JUN/CTSS/GADD45B/CTSB/MCL1/FOS/TNFRSF1A/CTSL/BCL2L11/CTSO/BIRC3/CTSF/NOL3/ATM/IKBKB	4.98265439540111
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	26/416	250/9376	2.344	HLA-B/FOLR2/DAB2/HLA-A/HSPA1A/HLA-E/HSPA1B/WWP1/CLTC/SMAP2/HSPA6/HLA-C/CYTH1/HLA-F/SNX6/EPS15/RABEP1/ZFYVE16/ARAP2/CXCR4/ARAP1/CYTH4/IQSEC3/DNM1/PML/CYTH3	4.64095480892257
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	9/416	42/9376	4.82967032967033	FTL/FTH1/NCOA4/HMOX1/SAT1/SLC40A1/ATG7/PRNP/SLC11A2	5.35957602497459
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	13/416	88/9376	3.32954545454546	F13A1/C1QA/C1QB/C2/A2M/C1QC/VSIG4/CD59/CR1/C5AR1/CFD/SERPINE1/C4BPB	4.73074697456272
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	21/416	196/9376	2.41483516483516	HLA-B/HLA-A/HLA-E/JUN/UBC/GNG7/HLA-C/FOS/TNFRSF1A/HLA-F/PDGFB/CD200R1/JAK2/ICAM1/IL6ST/NFATC2/CLEC2B/IKBKB/IFNAR1/SYK/STAT3	4.31311302681486
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	19/416	173/9376	2.47532236549578	HLA-DRA/DNAJB1/HLA-DPA1/TLR4/HLA-DRB1/TLR7/HLA-DPB1/HLA-DQA2/HLA-DMB/TNFRSF1A/HLA-DMA/RSAD2/JAK2/ICAM1/OAS1/IL18/IKBKB/PML/IFNAR1	4.2201080002046
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	9/416	50/9376	4.05692307692308	HLA-DRA/CD28/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/HLA-DMA/CXCR4	4.66981962275687
Organismal Systems	Digestive system	hsa04978	Mineral absorption	10/416	61/9376	3.69482976040353	FTL/FTH1/HMOX1/ATP2B1/SLC40A1/ATP1B1/CYBRD1/ATOX1/SLC11A2/SLC46A1	4.54970377668652
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	9/416	52/9376	3.9008875739645	APOE/PLTP/APOC1/ABCA1/NPC2/CD36/NPC1/MYLIP/CYP27A1	4.51970131962466
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	17/416	157/9376	2.44047035766781	C1QA/C1QB/ABCA1/CD36/GAS6/PLA2G15/C1QC/ITGB5/HAVCR2/STAB1/SIRPA/JAK2/CPT1A/NFATC2/ADAM9/EPOR/S1PR1	3.92184606290926
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	9/416	56/9376	3.62225274725275	HSPA1A/HSPA1B/CD14/TLR4/HSPA6/TLR5/CR1/CLK1/IL18	4.24071322958548
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	13/416	105/9376	2.79047619047619	LY96/GADD45B/CD14/TLR4/CCL13/TNFRSF1A/ICAM1/BIRC3/CYLD/ATM/IKBKB/TRAF5/SYK	3.97537596694613
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	21/416	238/9376	1.98868778280543	F13A1/C1QA/C1QB/C2/JUN/RPS4Y1/NRP1/FCGR2A/C1QC/TLR4/TLR7/FOS/TNFRSF1A/C5AR1/IL6ST/CFD/OAS1/IKBKB/IFNAR1/SYK/STAT3	3.32889707811433
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	10/416	78/9376	2.88954635108481	C1QA/C1QB/C2/LY96/JUN/CD14/C1QC/TLR4/FOS/C4BPB	3.61067483278656
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	19/416	214/9376	2.00107836089144	HLA-B/HLA-A/B2M/HLA-E/JUN/CD4/TLR4/BST2/GNG7/HLA-C/AP1S2/FOS/TNFRSF1A/HLA-F/NFATC2/CXCR4/ATM/IKBKB/TRAF5	3.19196496206624
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	18/416	201/9376	2.01836969001148	CSF1R/MAF/IGF1/GADD45B/BMP2K/CD14/TSPAN7/MITF/MEF2C/DDX5/FLI1/REL/BIRC3/CEBPA/ATM/RUNX1/PML/JMJD1C	3.14469663358566
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	8/416	62/9376	2.90818858560794	HSPA1A/IGF1/HSPA1B/FOXO3/HSPA6/PRKACB/ADCY7/CAT	3.24808450943543
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	13/416	133/9376	2.20300751879699	KLF2/IGF1/GADD45B/FOXO3/HOMER3/CAT/BCL2L11/GABARAP/RBL2/ATM/IKBKB/S1PR1/STAT3	3.01068961368441
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	7/416	50/9376	3.15538461538462	CD36/GYPC/TLR4/CD81/CR1/ICAM1/IL18	3.29261061473698
Human Diseases	Infectious disease: viral	hsa05162	Measles	13/416	136/9376	2.15441176470588	HSPA1A/HSPA1B/JUN/CD28/TLR4/HSPA6/TLR7/FOS/OAS1/STAT5A/IKBKB/IFNAR1/STAT3	2.92194819164422
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	15/416	169/9376	2.00045516613564	CTSD/CTSB/UBC/STX7/PRKACB/RRAGD/LAMP1/SQSTM1/CTSL/ATG7/GABARAP/RB1CC1/LAMP2/NBR1/C9orf72	2.82787501344156
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	9/416	80/9376	2.53557692307692	IGF1/GAS6/FOXO3/PDGFC/PDGFB/BCL2L11/JAK2/EIF4E/STAT3	2.97198635730493
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	11/416	109/9376	2.27452364149612	SPP1/LY96/JUN/CD14/TLR4/TLR7/FOS/TLR5/TLR1/IKBKB/IFNAR1	2.88383137096175
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	16/416	187/9376	1.92842451665981	TXNIP/JUN/CTSB/TLR4/CYBA/IFI16/CARD6/HSP90AA1/BIRC3/PKN2/OAS1/GABARAP/IL18/IKBKB/TRAF5/IFNAR1	2.7631952675638
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	17/416	205/9376	1.86904315196998	HLA-B/HLA-A/HLA-E/JUN/RBPJ/SCIN/HLA-C/PRKACB/HLA-F/IL6ST/REL/ATP6V0D1/RBL2/STAT5A/TRAF5/SYK/STAT3	2.71074224612207
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	14/416	157/9376	2.00979911807937	HLA-B/HLA-A/HLA-E/GADD45B/FOXO3/ZFP36L1/HLA-C/HLA-F/SQSTM1/NFATC2/ZFP36L2/RBL2/SERPINE1/ATM	2.74929412777414
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	8/416	68/9376	2.65158371040724	CSF1R/CD14/CEBPA/STAT5A/RUNX1/IKBKB/PML/STAT3	2.94513467175521
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	13/416	143/9376	2.04895104895105	C1QA/C1QB/C2/HLA-DRA/CD28/FCGR2A/C1QC/HLA-DPA1/HLA-DRB1/HLA-DPB1/HLA-DQA2/HLA-DMB/HLA-DMA	2.72351719297554
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	12/416	133/9376	2.03354540196645	HLA-B/HLA-A/TYROBP/HLA-E/HLA-C/FCER1G/ICAM1/NFATC2/SH3BP2/VAV1/IFNAR1/SYK	2.58658766329521
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	11/416	119/9376	2.08338720103426	JUN/JUNB/FOS/TNFRSF1A/ICAM1/BIRC3/BCL3/CYLD/IKBKB/TRAF5/RHBDF2	2.56271521955455
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	14/416	168/9376	1.87820512820513	FTL/GLUL/FTH1/TLR4/TNFRSF1A/SQSTM1/JAK2/HSP90AA1/BIRC3/CYLD/STAT5A/TRAF5/IFNAR1/STAT3	2.47483502106862
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	9/416	90/9376	2.25384615384615	IGF1/FOXO3/SESN1/SESN3/PRKACB/ADCY7/CAT/RB1CC1/EIF4E	2.5753097130402
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	9/416	90/9376	2.25384615384615	JUN/CD28/CD4/TLR4/FOS/JAK2/NFATC2/IKBKB/STAT3	2.5753097130402
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	25/416	362/9376	1.55652358691033	SPP1/CSF1R/IGF1/CSH1/FOXO3/TLR4/ITGB5/MCL1/GNG7/PDGFC/PDGFB/NR4A1/FN1/BCL2L11/JAK2/CSH2/HSP90AA1/PKN2/EIF4E/RBL2/VEGFB/IKBKB/EPOR/IFNAR1/SYK	2.3267910395546
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	9/416	91/9376	2.229078613694	JUN/LILRB5/FOS/CD81/NFATC2/INPP5D/VAV1/IKBKB/SYK	2.53856157876662
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	11/416	122/9376	2.03215636822194	IGF1/CSH1/JUNB/PRKACB/FOS/ADCY7/JAK2/CSH2/STAT5A/SOCS2/STAT3	2.47251515859835
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	12/416	138/9376	1.95986622073579	JUN/CD4/FCGR2A/TLR4/FOS/FN1/NFATC2/PKN2/IL18/BAIAP2/VAV1/IKBKB	2.44759507888844
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	12/416	139/9376	1.94576646375208	CTSD/HSPA1A/HSPA1B/JUN/KCNJ5/HSPA6/PRKACB/FOS/ADCY7/GPER1/HSP90AA1/FKBP5	2.42049470627605
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	17/416	227/9376	1.68790240596408	HLA-B/HLA-A/B2M/HLA-E/GNG7/HLA-C/PRKACB/TNFRSF1A/HLA-F/IL10RA/ADCY7/NFATC2/AKAP13/CXCR4/IKBKB/TRAF5/STAT3	2.26063913648975
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	12/416	144/9376	1.87820512820513	C1QA/C1QB/C2/LY96/CD14/C1QC/FOXO3/TLR4/TNFRSF1A/C5AR1/CPT1A/IKBKB	2.28827183750401
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/416	15/9376	4.50769230769231	HEXA/ST3GAL5/ST3GAL1	2.92943789961374
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	9/416	100/9376	2.02846153846154	CSF1R/TNFRSF14/CCL13/TNFRSF1A/IL10RA/CCL18/IL6ST/CXCR4/IL18	2.22785018976962
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	3/416	17/9376	3.97737556561086	NRP2/LAMP1/LAMP2	2.64741274732777
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	9/416	103/9376	1.96938013442868	C1QA/C1QB/JUN/C1QC/TLR4/FOS/TNFRSF1A/SERPINE1/IKBKB	2.13147820686652
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	4/416	30/9376	3.0051282051282	FOLR2/ABCC5/IKBKB/SLC46A1	2.3701082594295
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	7/416	73/9376	2.16122233930453	FEZ1/CD4/BST2/BICD1/CXCR4/AFF4/MDFIC	2.14606860045389
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	3/416	18/9376	3.75641025641026	HEXA/FUCA1/MANBA	2.52212663203184
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	9/416	105/9376	1.93186813186813	JUN/UBC/FOXO3/MITF/SQSTM1/GABARAP/NBR1/BNIP3L/PINK1	2.06901727903252
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	5/416	44/9376	2.56118881118881	MAN1A1/HEXA/MAN1C1/MGAT4A/MGAT1	2.2365195662397
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	20/416	300/9376	1.5025641025641	HSPA1A/CSF1R/IGF1/HSPA1B/JUN/GADD45B/DUSP1/CD14/HSPB1/HSPA6/PDGFC/PRKACB/FOS/JUND/TNFRSF1A/PDGFB/MEF2C/NR4A1/VEGFB/IKBKB	1.90626444118884
NA	NA	hsa04981	Folate transport and metabolism	4/416	31/9376	2.90818858560794	FOLR2/ABCC5/SLCO2B1/SLC46A1	2.29292994658698
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	7/416	75/9376	2.10358974358974	IGF1/GADD45B/SESN1/SESN3/ZMAT3/SERPINE1/ATM	2.06752973297377
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	3/416	19/9376	3.5587044534413	HEXA/GNS/NAGLU	2.40550857531542
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	17/416	248/9376	1.54497518610422	LY96/JUN/CD14/TLR4/RHOB/CYTH1/FOS/TNFRSF1A/TLR5/M6PR/HSP90AA1/BIRC3/CYTH4/IL18/DCTN4/IKBKB/CYTH3	1.87410125611982
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	4/416	32/9376	2.81730769230769	BIRC7/TNFRSF1A/BCL2L11/BIRC3	2.21878559593139
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	17/416	253/9376	1.51444207965947	JUN/UBC/CD14/FOXO3/TLR4/CYTH1/TNFRSF1A/CAST/RRAGD/TLR5/SQSTM1/CYTH4/IL18/ATM/IKBKB/TRAF5/CYTH3	1.7873360171735
NA	NA	hsa03272	Virion - Hepatitis viruses	5/416	48/9376	2.34775641025641	CD81/LAMP1/TGOLN2/LAMP2/CD63	2.01704717083103
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	8/416	97/9376	1.8588421887391	KCNJ5/GNG7/PRKACB/FOS/ADCY7/GRIN2C/PER3/RYR1	1.83200623966465
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	4/416	35/9376	2.57582417582418	HSD17B14/FBP1/PFKFB2/PFKFB3	2.01244209861549
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	9/416	115/9376	1.76387959866221	MAFB/PRKACB/FOS/JUND/MEF2C/NR4A2/ADCY7/AKAP13/MEF2A	1.77591914053082
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	12/416	168/9376	1.60989010989011	CSH1/MCL1/PDGFB/IL10RA/JAK2/IL6ST/CSH2/STAT5A/EPOR/IFNAR1/SOCS2/STAT3	1.71870711577862
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	5/416	51/9376	2.20965309200603	PLA2G7/ENPP2/PLD3/TMEM86A/PLD4	1.86637885871109
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	8/416	101/9376	1.78522467631379	JUN/FN1/JAK2/ICAM1/SERPINE1/STAT5A/VEGFB/STAT3	1.70952700495437
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	15/416	227/9376	1.48932565232125	JUN/NCF2/FOXO3/EPHX1/HMOX1/GSTT1/CYBA/FOS/UQCRB/CAT/NFE2L2/MT-ND2/MGST2/IKBKB/MT-ND5	1.60806054832079
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	5/416	53/9376	2.12626995645864	ATP2B1/CLTC/PRKACB/ATP1B1/DNM1	1.77166208379067
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	6/416	70/9376	1.93186813186813	CD36/TNFRSF1A/JAK2/CPT1A/IKBKB/STAT3	1.6861657151178
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	13/416	195/9376	1.5025641025641	NCF2/FCGR2A/TLR4/TLR7/CYBA/CR1/ATG7/FPR3/C5AR1/NCF4/SELPLG/FPR1/SYK	1.52806586759846
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	6/416	71/9376	1.90465872156013	FOXO3/FOS/JAK2/STAT5A/SOCS2/STAT3	1.64867122765131
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	5/416	55/9376	2.04895104895105	PSAP/ASAH1/HEXA/SGMS1/UGCG	1.68106153507426
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	20/416	333/9376	1.35366135366135	HLA-B/HLA-A/SPP1/HLA-E/RBPJ/ITGB5/HLA-C/PRKACB/TNFRSF1A/HLA-F/ATP6V0A1/FN1/APC/NOTCH2/ATP6V0D1/LFNG/RBL2/ATM/IKBKB/IFNAR1	1.41589730425972
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	3/416	26/9376	2.60059171597633	TCN2/ABCD4/SLC46A1	1.76092042975224
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	13/416	200/9376	1.465	JUN/FCGR2A/TLR4/CYTH1/FOS/TNFRSF1A/TLR5/CYTH4/IL18/BAIAP2/IKBKB/MYO5A/CYTH3	1.43225236140055
NA	NA	hsa04081	Hormone signaling	14/416	219/9376	1.44081489286969	IGF1/CSH1/GNG7/SLC40A1/PRKACB/ADCY7/JAK2/GPER1/CSH2/HAMP/THRA/STAT5A/EPOR/STAT3	1.42226331311743
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	7/416	94/9376	1.67839607201309	JUN/FOS/JUND/HSP90AA1/FOSB/IKBKB/TRAF5	1.42431080228146
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	4/416	45/9376	2.0034188034188	ABCA1/ABCC5/ABCG1/ABCD4	1.453793410465
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	8/416	116/9376	1.55437665782493	NCF2/CYBA/ICAM1/NCF4/CXCR4/CD99/ARHGAP5/VAV1	1.29451395298049
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	7/416	98/9376	1.60989010989011	KCNJ5/ATP2B1/PRKACB/NR4A2/NR4A1/ADCY7/ATP1B1	1.30772294320944
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	4/416	46/9376	1.95986622073579	FTL/FTH1/HMOX1/BLVRA	1.40613526774136
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	12/416	193/9376	1.40135512156238	FOXO3/GNG7/CXCL16/PRKACB/CCL13/CCL18/ADCY7/JAK2/CXCR4/VAV1/IKBKB/STAT3	1.21392951347447
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	7/416	99/9376	1.59362859362859	IGF1/JUN/PRKACB/FOS/ADCY7/GPER1/NOTCH2	1.27940171739428
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	11/416	174/9376	1.42484526967286	HSPA1A/MAN1A1/HSPA1B/DNAJB1/HSPA6/HSPH1/MAN1C1/NFE2L2/HSP90AA1/HERPUD1/DNAJA1	1.21882848488306
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/416	16/9376	2.81730769230769	HEXA/ST3GAL1	1.56757681148684
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	3/416	31/9376	2.18114143920596	GLUL/CAT/ACSS1	1.41929083819948
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	15/416	254/9376	1.33101150817686	HRH1/MCOLN1/ATP2B1/PDGFC/PRKACB/ORAI3/PDGFB/ADCY7/GRIN2C/NFATC2/TPCN1/CXCR4/RYR1/PTAFR/VEGFB	1.15237337630332
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	16/416	275/9376	1.31132867132867	C1QA/C1QB/HSPA1A/HSPA1B/NCF2/C1QC/HSPA6/CYBA/PRKACB/UQCRB/PRNP/GRIN2C/NCF4/MT-ND2/RYR1/MT-ND5	1.12906568045801
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	13/416	217/9376	1.35023041474654	JUN/EPHX1/KLF4/GSTT1/PRKACB/FOS/ADCY7/JAK2/HSP90AA1/NOTCH2/MGST2/STAT5A/STAT3	1.12470336505369
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	9/416	140/9376	1.4489010989011	SPP1/KLF2/GNG7/PRKACB/MEF2C/ADCY7/MEF2A/SERPINE1/RYR1	1.15305765390322
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	4/416	49/9376	1.83987441130298	JUN/PRKACB/GRIN2C/FOSB	1.27004672811019
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	17/416	298/9376	1.28575116159009	CSF1R/CSH1/TNFRSF14/CD4/CXCL16/TNFSF12/CCL13/TNFRSF1A/IL10RA/CCL18/IL6ST/CSH2/CXCR4/TNFRSF25/IL18/EPOR/IFNAR1	1.08013825091676
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	2/416	17/9376	2.65158371040724	GLUL/CA8	1.46854962427756
NA	NA	hsa04517	IgSF CAM signaling	17/416	299/9376	1.28145099048109	PMP22/MTSS1/CD28/CD84/NRP1/NRP2/MBP/EPB41L1/ICAM1/PLXNA1/DOK2/INPP5D/EPB41L3/CASK/BAIAP2/VAV1/CADM1	1.06572586579327
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	4/416	50/9376	1.80307692307692	AOC1/SAT1/LAP3/GATM	1.22679710270714
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	7/416	105/9376	1.5025641025641	JUN/FCER1G/NFATC2/BCL3/CYLD/IKBKB/SYK	1.11583793507571
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	2/416	18/9376	2.5042735042735	TCN2/ABCD4	1.37641639453521
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	4/416	51/9376	1.76772247360483	PRKACB/ATP6V0A1/KCNQ1/ATP6V0D1	1.18452224324682
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	3/416	34/9376	1.98868778280543	BHLHE41/NR1D2/PER3	1.2443913779793
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	7/416	106/9376	1.48838896952104	FOLR2/IGF1/PDGFC/PDGFB/HSP90AA1/IKBKB/SLC46A1	1.08957520316487
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	5/416	69/9376	1.63322185061316	JUN/PRKACB/FOS/GRIN2C/FOSB	1.13750648102778
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	12/416	204/9376	1.32579185520362	IGF1/TLR4/ITGB5/TIMP3/PRKACB/DDX5/ANK1/FN1/CTSL/CD63/VAV1/STAT3	1.01368164367174
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	6/416	89/9376	1.51944684528954	GLUL/GNG7/PRKACB/GABRA3/ADCY7/GABARAP	1.06090547892818
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	7/416	110/9376	1.43426573426573	IGF1/TLR4/HMOX1/EIF4E/SERPINE1/PFKFB3/STAT3	0.987152059754577
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	9/416	149/9376	1.36138358286009	PDGFC/CYTH1/FCER1G/PDGFB/ADCY7/CYTH4/DNM1/CYTH3/SYK	0.958097246147302
Human Diseases	Cancer: specific types	hsa05218	Melanoma	5/416	73/9376	1.54373024236038	IGF1/GADD45B/MITF/PDGFC/PDGFB	1.00487422670981
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/416	37/9376	1.82744282744283	ICAM1/APOL1/IL18	1.08659316462956
Organismal Systems	Digestive system	hsa04970	Salivary secretion	6/416	93/9376	1.45409429280397	LYZ/ATP2B1/CST3/PRKACB/ADCY7/ATP1B1	0.948247357942097
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	6/416	93/9376	1.45409429280397	GADD45B/BIRC7/FN1/BIRC3/IKBKB/TRAF5	0.948247357942097
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	4/416	56/9376	1.60989010989011	MAN1A1/MAN1C1/MGAT4A/MGAT1	0.986315701380803
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	2/416	21/9376	2.14652014652015	VNN1/VNN2	1.13330744203324
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	9/416	154/9376	1.31718281718282	JUN/KCNJ5/RGS2/PRKACB/FOS/MEF2C/ADCY7/NFATC2/RYR1	0.855137107208358
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	5/416	76/9376	1.48279352226721	PLTP/CD36/UBC/CPT1A/CYP27A1	0.910552633968843
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	2/416	22/9376	2.04895104895105	AOC1/ALDH3B1	1.06131958345002
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	6/416	98/9376	1.37990580847724	MARCKS/SCIN/FCGR2A/INPP5D/VAV1/SYK	0.814591897700605
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	5/416	79/9376	1.42648490749757	EPHX1/GSTT1/DHDH/MGST2/ALDH3B1	0.820208179110529
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	5/416	79/9376	1.42648490749757	CLTC/ATP6V0A1/SYT1/DNM1/ATP6V0D1	0.820208179110529
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	2/416	24/9376	1.87820512820513	HS2ST1/HS3ST2	0.928170239523579
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	11/416	203/9376	1.22129594543388	SPP1/IGF1/JUN/ITGB5/PDGFC/PDGFB/FN1/BIRC3/ARHGAP5/VAV1/VEGFB	0.686821810102838
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	4/416	62/9376	1.45409429280397	RBPJ/NOTCH2/LFNG/TLE4	0.772951190151735
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	7/416	122/9376	1.29319041614124	CD36/IGF1/FOXO3/CPT1A/FBP1/PFKFB2/PFKFB3	0.702333261300082
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	7/416	122/9376	1.29319041614124	JUN/CD28/CD4/FOS/NFATC2/VAV1/IKBKB	0.702333261300082
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	9/416	163/9376	1.2444549315715	JUN/TLR4/FOS/JAK2/NFATC2/STAT5A/IKBKB/IFNAR1/STAT3	0.67837583372618
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	3/416	44/9376	1.53671328671329	PRKACB/STX4/DCTN4	0.768881866557211
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	6/416	104/9376	1.30029585798817	PLA2G15/PLD3/CDS1/PLD4/SGMS1/CDS2	0.663525470817431
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	12/416	232/9376	1.1657824933687	SCIN/ITGB5/PDGFC/IQGAP2/PDGFB/FN1/RGCC/APC/CXCR4/TMSB4X/BAIAP2/VAV1	0.550925468397705
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	8/416	149/9376	1.21011874032008	KCNJ5/GNG7/PRKACB/MGLL/GABRA3/ADCY7/MT-ND2/MT-ND5	0.557065113117074
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	5/416	87/9376	1.29531388152078	JUN/GADD45B/FOS/BCL2L11/APC	0.596262237464671
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	6/416	109/9376	1.24064925899788	CD36/TNFRSF1A/CPT1A/MLXIP/IKBKB/STAT3	0.544510795956787
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/416	28/9376	1.60989010989011	ATP6V0A1/ATP6V0D1	0.696385233097158
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	4/416	69/9376	1.30657748049052	FCER1G/INPP5D/VAV1/SYK	0.550729370215916
NA	NA	hsa04518	Integrin signaling	8/416	154/9376	1.17082917082917	SPP1/IGF1/ITGB5/PDGFC/PDGFB/FN1/ICAM1/VEGFB	0.460562032543714
Human Diseases	Substance dependence	hsa05032	Morphine addiction	5/416	91/9376	1.23837700760778	KCNJ5/GNG7/PRKACB/GABRA3/ADCY7	0.492348256679633
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	4/416	71/9376	1.26977248104009	JUN/ATP6V0A1/ATP6V0D1/IKBKB	0.4916396834553
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	9/416	178/9376	1.13958513396716	JUN/PRKACB/APC/NFATC2/ROR1/DKK2/LZTS2/DAAM1/TLE4	0.405117277034357
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	8/416	157/9376	1.1484566389025	JUN/FOS/TNFRSF1A/UQCRB/BCL2L11/MLXIP/CEBPA/IKBKB	0.404190257503913
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	6/416	115/9376	1.17591973244147	GNG7/PRKACB/FOS/ADCY7/KCNQ1/JAK2	0.408990134815767
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	4/416	73/9376	1.2349841938883	GADD45B/FOXO3/STAT5A/STAT3	0.434277039837766
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/416	52/9376	1.30029585798817	IGF1/PRKACB/ADCY7	0.467873211567469
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	6/416	116/9376	1.1657824933687	GLUL/HOMER3/GNG7/PRKACB/ADCY7/GRIN2C	0.387115416561151
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	2/416	32/9376	1.40865384615385	ATG7/GABARAP	0.49893326892637
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/416	12/9376	1.87820512820513	NPC1	0.655894800317664
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	4/416	75/9376	1.20205128205128	GSTT1/BIRC3/MGST2/ATM	0.378534718769361
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	2/416	33/9376	1.36596736596737	STX7/STX4	0.453768614897305
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	4/416	76/9376	1.18623481781377	PRKACB/ADCY7/ATP1B1/KCNQ1	0.351240429036199
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	4/416	77/9376	1.17082917082917	GADD45B/STAT5A/RUNX1/IKBKB	0.324315399138006
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	8/416	166/9376	1.08619091751622	RGS2/ATP2B1/MEF2C/ADCY7/ATP1B1/NFATC2/GTF2I/MEF2A	0.241414878020819
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	4/416	78/9376	1.15581854043392	BTG2/PABPC1/TOB1/CNOT6L	0.29774875969743
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	7/416	144/9376	1.09561965811966	IGF1/ZFHX3/KLF4/JAK2/APC/IL6ST/STAT3	0.249148819290278
Metabolism	Glycan biosynthesis and metabolism	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/416	14/9376	1.60989010989011	ST3GAL1	0.492050399700128
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	2/416	36/9376	1.25213675213675	CRYL1/DHDH	0.326582015670407
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	6/416	125/9376	1.08184615384615	ASAH1/CTSD/FCER1G/TNFRSF1A/SGMS1/S1PR1	0.198489364087988
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	5/416	103/9376	1.0941000746826	CD14/TLR4/HSPB1/PRKACB/FN1	0.206907745812929
Organismal Systems	Immune system	hsa04611	Platelet activation	6/416	126/9376	1.07326007326007	FCGR2A/PRKACB/FCER1G/TBXAS1/ADCY7/SYK	0.178385706806596
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/416	59/9376	1.14602346805737	GSTT1/MGST2/LAP3	0.242431425684016
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	3/416	59/9376	1.14602346805737	PRKACB/MGLL/ADCY7	0.242431425684016
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	3/416	59/9376	1.14602346805737	GADD45B/FOXO3/APC	0.242431425684016
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/416	37/9376	1.21829521829522	GADD45B/NCOA4	0.286664025844483
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	4/416	83/9376	1.08619091751622	IFI16/DNASE2/IL18/IKBKB	0.169942060702715
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	2/416	38/9376	1.18623481781377	HEXA/AMDHD2	0.24785862757069
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	2/416	38/9376	1.18623481781377	IGF1/ATP1B1	0.24785862757069
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/416	16/9376	1.40865384615385	ALDH3B1	0.352497431154448
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/416	130/9376	1.04023668639053	JUN/GNG7/PRKACB/FOS/ADCY7/VEGFB	0.0995394503744728
Metabolism	Lipid metabolism	hsa00120	Primary bile acid biosynthesis	1/416	17/9376	1.32579185520362	CYP27A1	0.289686501227355
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	7/416	156/9376	1.01134122287968	TNFRSF1A/RSAD2/CD81/OAS1/IKBKB/IFNAR1/STAT3	0.0307776192499778
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	2/416	41/9376	1.09943714821764	SDS/GATM	0.137487028750697
Human Diseases	Substance dependence	hsa05033	Nicotine addiction	2/416	41/9376	1.09943714821764	GABRA3/GRIN2C	0.137487028750697
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	3/416	65/9376	1.04023668639053	PRKACB/NR4A1/ADCY7	0.0701389115126665
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	3/416	65/9376	1.04023668639053	SPP1/KCNJ5/GPER1	0.0701389115126665
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/416	89/9376	1.01296456352636	SPP1/CD36/ITGB5/FN1	0.0264785061296552
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	4/416	89/9376	1.01296456352636	PDGFC/PRKACB/PDGFB/ADCY7	0.0264785061296552
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	9/416	205/9376	0.989493433395872	CTSD/CD36/PDK4/NCF2/CYBA/UQCRB/NCF4/MT-ND2/MT-ND5	-0.0327723587614069
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/416	42/9376	1.07326007326007	AOC1/CAT	0.102526561931604
Organismal Systems	Digestive system	hsa04976	Bile secretion	4/416	90/9376	1.0017094017094	EPHX1/PRKACB/ADCY7/ATP1B1	0.00351098802050476
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	2/416	43/9376	1.04830053667263	ABCA1/CD36	0.0683996453354433
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	3/416	67/9376	1.00918484500574	ACSS1/ALDH3B1/FBP1	0.0162568357118161
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	6/416	138/9376	0.979933110367893	PRKACB/RHOQ/EIF4E/IKBKB/FBP1/SOCS2	-0.0511692350987131
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/416	20/9376	1.12692307692308	NPL	0.122430262837619
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	3/416	70/9376	0.965934065934066	EPHX1/GSTT1/MGST2	-0.0616404919441647
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/416	47/9376	0.959083469721768	IKBKB/SOCS2	-0.0605910501344914
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	3/416	73/9376	0.926238145416228	GSTT1/MGST2/ALDH3B1	-0.136320147034276
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	5/416	122/9376	0.923707440100883	PRKACB/ATP1B1/THRA/NOTCH2/PFKFB2	-0.182757687349054
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	4/416	98/9376	0.919937205651491	PI4K2A/CDS1/INPP5D/CDS2	-0.17167019331707
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/416	99/9376	0.910644910644911	HRH1/IGF1/PRKACB/ADCY7	-0.192580101440238
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	4/416	99/9376	0.910644910644911	JUN/PDGFC/FOS/PDGFB	-0.192580101440238
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	6/416	148/9376	0.913721413721414	IGF1/JUN/GADD45B/FOS/APC/NOTCH2	-0.227959861160301
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/416	23/9376	0.979933110367893	GLUL	-0.0207609303560519
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/416	23/9376	0.979933110367893	ATP6AP2	-0.0207609303560519
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/416	23/9376	0.979933110367893	ATP1B1	-0.0207609303560519
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/416	75/9376	0.901538461538462	PRKACB/ADCY7/ATP1B1	-0.184463619298775
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	4/416	101/9376	0.892612338156893	MITF/PRKACB/ADCY7/ASIP	-0.233795642772615
Human Diseases	Cancer: specific types	hsa05214	Glioma	3/416	76/9376	0.889676113360324	IGF1/GADD45B/PDGFB	-0.208071775896444
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	4/416	102/9376	0.883861236802413	ATP2B1/ADCY7/ATP1B1/KCNQ1	-0.254110163455112
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/416	77/9376	0.878121878121878	GADD45B/IKBKB/STAT3	-0.231382916344075
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	4/416	103/9376	0.875280059746079	SLC7A8/ATP1B1/KCNQ1/KCNE3	-0.274234869450469
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/416	78/9376	0.866863905325444	CLTC/FN1/DNM1	-0.254405585817424
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	13/416	323/9376	0.907120743034056	MARCKS/ZEB2/HMOX1/MCL1/TIMP3/PDGFB/BCL2L11/APC/FOXP1/NOTCH2/ATM/IKBKB/STAT3	-0.366017653139829
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	6/416	154/9376	0.878121878121878	ATP2B1/SCN1B/PRKACB/ADCY7/ATP1B1/KCNQ1	-0.328588116785574
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	4/416	105/9376	0.858608058608059	IGF1/ITGB5/PRKACB/ADCY7	-0.313931080859494
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	4/416	107/9376	0.842559309849029	PRKACB/CPT1A/FBP1/SIK1	-0.352915498668137
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	3/416	82/9376	0.824577861163227	GSTT1/MGST2/TK2	-0.343770252113991
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	2/416	56/9376	0.804945054945055	PRKACB/DISP1	-0.315443309901068
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	3/416	83/9376	0.814643188137164	CAT/PEX11G/ABCD4	-0.36546679721014
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/416	28/9376	0.804945054945055	PPT1	-0.222717799774316
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	4/416	110/9376	0.81958041958042	IGF1/PRKACB/ADCY7/HSP90AA1	-0.41012114559852
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/416	57/9376	0.790823211875843	CPT1A/PPT1	-0.341306501240747
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	8/416	212/9376	0.850507982583454	CSF1R/IGF1/PDGFC/PDGFB/ADCY7/FPR1/VAV1/VEGFB	-0.474374889073578
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	9/416	238/9376	0.85229476405947	CSF1R/IGF1/GNG7/PDGFC/PRKACB/PDGFB/REL/VEGFB/IKBKB	-0.497321335305084
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	5/416	138/9376	0.816610925306578	ATP6V0A1/UQCRB/MT-ND2/ATP6V0D1/MT-ND5	-0.467629954096573
Organismal Systems	Sensory system	hsa04742	Taste transduction	3/416	86/9376	0.786225402504472	SCN9A/PRKACB/GABRA3	-0.42911704418594
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/416	86/9376	0.786225402504472	PRKACB/ADCY7/ATP1B1	-0.42911704418594
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/416	60/9376	0.751282051282051	HSPB1/NFATC2	-0.416434125293065
Organismal Systems	Nervous system	hsa04730	Long-term depression	2/416	60/9376	0.751282051282051	IGF1/RYR1	-0.416434125293065
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/416	31/9376	0.727047146401985	FBP1	-0.327987378575511
Metabolism	Carbohydrate metabolism	hsa00053	Ascorbate and aldarate metabolism	1/416	31/9376	0.727047146401985	HSD17B14	-0.327987378575511
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/416	31/9376	0.727047146401985	ALDH3B1	-0.327987378575511
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	4/416	115/9376	0.783946488294314	KCNJ5/DUSP1/GNG7/PRKACB	-0.502295868994269
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	5/416	142/9376	0.793607800650054	WWP1/UBC/BIRC7/BIRC3/PML	-0.533974865168011
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	4/416	116/9376	0.777188328912467	CAT/SDS/ACSS1/FBP1	-0.520283119858187
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/416	32/9376	0.704326923076923	ACSS1	-0.360992894576138
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	6/416	170/9376	0.795475113122172	GADD45B/HMOX1/GSTT1/APC/NFE2L2/MGST2	-0.579847027581618
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	5/416	144/9376	0.78258547008547	RBPJ/GRIN2C/RB1CC1/PUM2/RYR1	-0.566500387995214
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/416	63/9376	0.715506715506715	LTC4S/TBXAS1	-0.488175288056821
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/416	63/9376	0.715506715506715	GADD45B/APC	-0.488175288056821
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/416	93/9376	0.727047146401985	JUN/PRKACB/ADCY7	-0.569984750675578
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	8/416	226/9376	0.797821647379169	JUN/ATP2B1/PRKACB/FOS/ADCY7/ATP1B1/GRIN2C/VAV1	-0.662913135778972
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/416	67/9376	0.672789896670494	PRKACB/GRIN2C	-0.579149772233449
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/416	36/9376	0.626068376068376	ST3GAL1	-0.484337735104418
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/416	36/9376	0.626068376068376	POLE	-0.484337735104418
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/416	37/9376	0.609147609147609	GLUL	-0.513265112940597
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/416	37/9376	0.609147609147609	ALDH3B1	-0.513265112940597
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/416	69/9376	0.653288740245262	CTSB/PRKACB	-0.622824851407818
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/416	38/9376	0.593117408906883	CD4	-0.541517218931617
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/416	70/9376	0.643956043956044	JUN/PDGFB	-0.644242560964818
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/416	72/9376	0.626068376068376	CYLD/IKBKB	-0.686280867627984
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	5/416	158/9376	0.713242453748783	IGF1/TNFRSF1A/RRAGD/EIF4E/IKBKB	-0.783255306342185
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/416	41/9376	0.549718574108818	ATM	-0.62258277170127
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/416	268/9376	0.756888633754305	DUSP1/UBC/PRKACB/UQCRB/NFE2L2/MT-ND2/SLC11A2/PINK1/MT-ND5	-0.870040458761466
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	4/416	133/9376	0.677848467322152	KCNJ5/GNG7/PRKACB/FOS	-0.806227939818374
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/416	75/9376	0.601025641025641	GLUL/SDS	-0.747461957366911
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/416	43/9376	0.524150268336315	CPT1A	-0.673863172563997
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	1/416	44/9376	0.512237762237762	GTF2I	-0.698755833125283
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/416	44/9376	0.512237762237762	POLE	-0.698755833125283
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/416	78/9376	0.577909270216962	PI4K2A/INPP5D	-0.806559931332279
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/416	110/9376	0.614685314685315	NBL1/ZFYVE16/HAMP	-0.875878880716219
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/416	46/9376	0.489966555183946	PSMB9	-0.747162468050721
NA	NA	hsa04082	Neuroactive ligand signaling	6/416	199/9376	0.67955160417472	HRH1/GNG7/PRKACB/GABRA3/ADCY7/GRIN2C	-0.984492864734527
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/416	47/9376	0.479541734860884	ACSS1	-0.77071815771073
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/416	48/9376	0.469551282051282	ATP1B1	-0.793867554750381
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/416	49/9376	0.459968602825746	LFNG	-0.816628176579261
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	12/416	368/9376	0.73494983277592	TNFRSF1A/SQSTM1/UQCRB/CAT/GRIN2C/MT-ND2/NUP214/RB1CC1/C9orf72/PINK1/DCTN4/MT-ND5	-1.1176764541287
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/416	86/9376	0.524150268336315	JUN/STAT5A	-0.955189403794646
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	12/416	370/9376	0.730977130977131	HRH1/CSH1/GABRA3/FPR3/C5AR1/GRIN2C/CSH2/THRA/NR3C1/FPR1/PTAFR/S1PR1	-1.13763354473288
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	7/416	235/9376	0.671358428805237	PRKACB/MGLL/ADCY7/UQCRB/CPT1A/MT-ND2/MT-ND5	-1.09935479141613
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/416	87/9376	0.518125552608311	UQCRB/ATP1B1	-0.972942872509717
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/416	120/9376	0.563461538461538	JUN/FOXO3/IKBKB	-1.03700240187963
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	16/416	480/9376	0.751282051282051	UBC/TNFRSF1A/SQSTM1/UQCRB/CAT/APC/PRNP/GRIN2C/MT-ND2/DKK2/RB1CC1/C9orf72/PINK1/DCTN4/RYR1/MT-ND5	-1.20533746979023
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/416	54/9376	0.417378917378917	SDS	-0.925138650193096
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	4/416	155/9376	0.581637717121588	PRKACB/NR4A1/ADCY7/APC	-1.13163836068085
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/416	93/9376	0.484698097601323	PTPRM/BAIAP2	-1.0760621202148
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	4/416	158/9376	0.570593962999026	GADD45B/ATRX/RBL2/ATM	-1.17288825160239
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	12/416	388/9376	0.697065820777161	APOE/RTN4/TNFRSF1A/UQCRB/APC/GRIN2C/MT-ND2/DKK2/SLC11A2/RB1CC1/IKBKB/MT-ND5	-1.31313962271183
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/416	59/9376	0.382007822685789	TK2	-1.02600442655557
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/416	99/9376	0.455322455322455	IGF1/ITGB5	-1.17390131399658
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/416	63/9376	0.357753357753358	ASH1L	-1.10206095072055
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/416	63/9376	0.357753357753358	POLE	-1.10206095072055
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/416	65/9376	0.346745562130177	MGLL	-1.13872585749976
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	3/416	138/9376	0.489966555183946	IGF1/PRKACB/ADCY7	-1.30055139209229
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/416	66/9376	0.341491841491841	HSD17B11	-1.15674221659854
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/416	68/9376	0.331447963800905	ALDH1A1	-1.19217437740228
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/416	184/9376	0.489966555183946	NRP1/NFATC2/CXCR4/PLXNA1	-1.50550033922348
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/416	117/9376	0.385272846811308	BAZ2B/RSF1	-1.44168899833409
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/416	157/9376	0.430671239588437	APC/BIRC3/SERPINE1	-1.55006296772128
Human Diseases	Substance dependence	hsa05034	Alcoholism	4/416	191/9376	0.472009665726943	GNG7/PRKACB/GRIN2C/FOSB	-1.58847862098661
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/416	83/9376	0.271547729379055	CBX6	-1.43628451303585
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/416	85/9376	0.265158371040724	TK2	-1.46639267557966
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/416	86/9376	0.262075134168157	ITGB5	-1.48126176340335
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/416	170/9376	0.397737556561086	JUN/PRKACB/RUNX1	-1.707469897591
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/416	134/9376	0.336394948335247	PRKACB/ADCY7	-1.66708367696005
NA	NA	hsa04519	Cadherin signaling	10/416	404/9376	0.557882711348058	SCN1B/GABRA3/LHFPL2/PCDH12/APC/DAAM1/RERE/VAV1/IKBKB/FMN1	-1.95732005858126
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/416	103/9376	0.21882001493652	PABPC1	-1.71766271524066
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/416	150/9376	0.300512820512821	GADD45B/APC	-1.86078828000777
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/416	108/9376	0.208689458689459	NUP214	-1.78214942581815
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/416	194/9376	0.34853291038858	MYO9B/DCTN4/MYO5A	-1.97561811933919
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/416	233/9376	0.386926378342687	ITGB5/ATP1B1/FN1/DAAM1	-2.04185326888587
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	6/416	308/9376	0.439060939060939	CLTC/UQCRB/MT-ND2/RB1CC1/DCTN4/MT-ND5	-2.15681842209676
Genetic Information Processing	Transcription	hsa03040	Spliceosome	4/416	243/9376	0.371003482114593	HSPA1A/HSPA1B/HSPA6/DDX5	-2.14053802853948
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/416	128/9376	0.176081730769231	ADCY7	-2.02229033283247
NA	NA	hsa04382	Cornified envelope formation	2/416	217/9376	0.207727756114853	S100A1/UGCG	-2.54424293612855
Genetic Information Processing	Translation	hsa03010	Ribosome	1/416	222/9376	0.101524601524602	RPS4Y1	-2.91914401892027
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	3/416	449/9376	0.150591057049854	RGS2/GNG7/PRKACB	-3.97434469629588