ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0035091 phosphatidylinositol binding 92/3070 284/18639 0.323943661971831 1.96677065651236 2.30445379121887e-11 3.03035673545281e-08 GO:0030695 GTPase regulator activity 133/3070 489/18639 0.2719836400818 1.65130393077676 9.22008486978015e-10 3.86973615264308e-07 GO:0060589 nucleoside-triphosphatase regulator activity 133/3070 490/18639 0.271428571428571 1.64793392275477 1.06381564816743e-09 3.86973615264308e-07 GO:0044389 ubiquitin-like protein ligase binding 96/3070 322/18639 0.298136645962733 1.81008760394117 1.35755997227631e-09 3.86973615264308e-07 GO:0005543 phospholipid binding 134/3070 497/18639 0.269617706237425 1.6369395526252 1.4713825675449e-09 3.86973615264308e-07 GO:0023026 MHC class II protein complex binding 18/3070 27/18639 0.666666666666667 4.04755700325733 7.86075424932517e-09 1.72281530631043e-06 GO:0031625 ubiquitin protein ligase binding 89/3070 302/18639 0.294701986754967 1.78923463554587 9.94178393555716e-09 1.86763512503681e-06 GO:0003779 actin binding 117/3070 443/18639 0.26410835214447 1.60349041551165 5.54067815343075e-08 9.1074897147018e-06 GO:0023023 MHC protein complex binding 20/3070 37/18639 0.540540540540541 3.28180297561405 1.84285907955791e-07 2.69262187735406e-05 GO:0005096 GTPase activator activity 78/3070 271/18639 0.287822878228782 1.74746925970888 2.33764316799777e-07 3.07400076591706e-05 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 68/3070 229/18639 0.296943231441048 1.80284198398361 3.88182588253036e-07 4.64054639593402e-05 GO:0140297 DNA-binding transcription factor binding 122/3070 488/18639 0.25 1.5178338762215 7.13238732941376e-07 7.81590778181591e-05 GO:0051787 misfolded protein binding 12/3070 17/18639 0.705882352941177 4.28564859168423 1.06729901018499e-06 0.000107961399876405 GO:0031072 heat shock protein binding 44/3070 131/18639 0.33587786259542 2.03922719248079 1.19127942980989e-06 0.000111895175014286 GO:0046915 transition metal ion transmembrane transporter activity 21/3070 45/18639 0.466666666666667 2.83328990228013 2.18560515070028e-06 0.000191604718211391 GO:0106310 protein serine kinase activity 93/3070 361/18639 0.257617728531856 1.56408366192354 3.89393886480302e-06 0.000320033100450999 GO:0015923 mannosidase activity 11/3070 16/18639 0.6875 4.17404315960912 4.61663106000583e-06 0.000357109990818098 GO:0019207 kinase regulator activity 77/3070 287/18639 0.268292682926829 1.62889489155478 5.34257466855926e-06 0.000390304760508635 GO:0051087 protein-folding chaperone binding 43/3070 134/18639 0.32089552238806 1.94826437843357 5.99493795394948e-06 0.000414912811023346 GO:0051020 GTPase binding 82/3070 315/18639 0.26031746031746 1.58047463936715 9.34758513682897e-06 0.000600566170104951 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 89/3070 349/18639 0.255014326647564 1.54827753562995 9.59079054920454e-06 0.000600566170104951 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 32/3070 91/18639 0.351648351648352 2.13497512259727 1.12573043391428e-05 0.000670064265762486 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 24/3070 60/18639 0.4 2.4285342019544 1.17197552186595e-05 0.000670064265762486 GO:1901505 carbohydrate derivative transmembrane transporter activity 22/3070 53/18639 0.415094339622642 2.52017700202815 1.33622532901794e-05 0.00073214012819108 GO:0016798 hydrolase activity, acting on glycosyl bonds 41/3070 130/18639 0.315384615384615 1.91480581307943 1.56014320147899e-05 0.000819988883320021 GO:0005484 SNAP receptor activity 17/3070 36/18639 0.472222222222222 2.86701954397394 1.66784976217754e-05 0.000819988883320021 GO:0015605 organophosphate ester transmembrane transporter activity 21/3070 50/18639 0.42 2.54996091205212 1.68362736499168e-05 0.000819988883320021 GO:0004559 alpha-mannosidase activity 10/3070 15/18639 0.666666666666667 4.04755700325733 1.94673524325946e-05 0.000914270301745069 GO:0000149 SNARE binding 35/3070 106/18639 0.330188679245283 2.0046862516133 2.15071430546181e-05 0.000954352560346007 GO:1901981 phosphatidylinositol phosphate binding 53/3070 185/18639 0.286486486486487 1.73935557707545 2.17723017569431e-05 0.000954352560346007 GO:0005525 GTP binding 93/3070 378/18639 0.246031746031746 1.49374127501163 2.81077658369368e-05 0.00119231329276038 GO:0046332 SMAD binding 28/3070 79/18639 0.354430379746835 2.15186574856719 3.30508096565845e-05 0.00135818170932527 GO:0005085 guanyl-nucleotide exchange factor activity 62/3070 230/18639 0.269565217391304 1.63662087523014 3.61662380400598e-05 0.0013999925880162 GO:0003924 GTPase activity 83/3070 331/18639 0.250755287009063 1.522419477056 3.6197526990533e-05 0.0013999925880162 GO:0042605 peptide antigen binding 19/3070 45/18639 0.422222222222222 2.56345276872964 3.85742305959322e-05 0.00144928894953288 GO:0015932 nucleobase-containing compound transmembrane transporter activity 22/3070 57/18639 0.385964912280702 2.34332247557003 5.14982795524987e-05 0.00188111771143155 GO:0016417 S-acyltransferase activity 14/3070 29/18639 0.482758620689655 2.93098955408289 6.86907235537085e-05 0.00244130544521964 GO:0031267 small GTPase binding 72/3070 283/18639 0.254416961130742 1.54465072915827 7.06294220139546e-05 0.0024441497354829 GO:0004674 protein serine/threonine kinase activity 102/3070 433/18639 0.235565819861432 1.43019912586229 7.67835735168978e-05 0.00258898459422361 GO:0019887 protein kinase regulator activity 66/3070 255/18639 0.258823529411765 1.57140448361755 8.01151497345305e-05 0.00263378554752269 GO:0008429 phosphatidylethanolamine binding 10/3070 17/18639 0.588235294117647 3.57137382640353 9.14968617234311e-05 0.00293459446747102 GO:0019001 guanyl nucleotide binding 95/3070 400/18639 0.2375 1.44194218241042 9.68695590662215e-05 0.00296240628307166 GO:0032561 guanyl ribonucleotide binding 95/3070 400/18639 0.2375 1.44194218241042 9.68695590662215e-05 0.00296240628307166 GO:0016407 acetyltransferase activity 31/3070 96/18639 0.322916666666667 1.96053542345277 9.95107949671532e-05 0.00297401580413196 GO:0042625 ATPase-coupled ion transmembrane transporter activity 12/3070 24/18639 0.5 3.035667752443 0.000149273351980372 0.00417647782668486 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 12/3070 24/18639 0.5 3.035667752443 0.000149273351980372 0.00417647782668486 GO:0046961 proton-transporting ATPase activity, rotational mechanism 12/3070 24/18639 0.5 3.035667752443 0.000149273351980372 0.00417647782668486 GO:0140857 histone H3T45 kinase activity 63/3070 246/18639 0.25609756097561 1.55485421466593 0.000158748016535829 0.00434903420301281 GO:0019905 syntaxin binding 22/3070 61/18639 0.360655737704918 2.18966198536872 0.000167187785495538 0.00443360907396052 GO:0022804 active transmembrane transporter activity 105/3070 457/18639 0.229759299781182 1.39494579433923 0.000169556471570764 0.00443360907396052 GO:0015399 primary active transmembrane transporter activity 46/3070 166/18639 0.27710843373494 1.68241827243829 0.000174157516430369 0.00443360907396052 GO:0035403 histone H3T6 kinase activity 63/3070 247/18639 0.255060728744939 1.54855925833125 0.000179405568026432 0.00443360907396052 GO:0019787 ubiquitin-like protein transferase activity 109/3070 479/18639 0.227557411273486 1.38157739046466 0.000191116881526562 0.00443360907396052 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 62/3070 243/18639 0.255144032921811 1.54906502593799 0.000199015657105987 0.00443360907396052 GO:0043130 ubiquitin binding 31/3070 100/18639 0.31 1.88211400651466 0.000229227309622776 0.00443360907396052 GO:0002020 protease binding 39/3070 136/18639 0.286764705882353 1.74104474037172 0.000244919926272821 0.00443360907396052 GO:0032395 MHC class II receptor activity 7/3070 10/18639 0.7 4.2499348534202 0.000246572013198736 0.00443360907396052 GO:1905394 retromer complex binding 7/3070 10/18639 0.7 4.2499348534202 0.000246572013198736 0.00443360907396052 GO:0004676 3-phosphoinositide-dependent protein kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0004711 ribosomal protein S6 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0035175 histone H3S10 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0035979 histone H2AXS139 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0044022 histone H3S28 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0044023 histone H4S1 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0044024 histone H2AS1 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0044025 histone H2BS14 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0072354 histone H3T3 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0072371 histone H2AS121 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0072518 Rho-dependent protein serine/threonine kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0140823 histone H2BS36 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0140855 histone H3S57 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0140995 histone H2A kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0140997 histone H4 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0140998 histone H2B kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:1990244 histone H2AT120 kinase activity 62/3070 245/18639 0.253061224489796 1.53641959715482 0.000253227236448407 0.00443360907396052 GO:0048156 tau protein binding 17/3070 43/18639 0.395348837209302 2.40029543216423 0.000256239003514068 0.00443360907396052 GO:0004677 DNA-dependent protein kinase activity 62/3070 246/18639 0.252032520325203 1.53017398903631 0.000285062625766778 0.0048682773101729 GO:0035402 histone H3T11 kinase activity 62/3070 247/18639 0.251012145748988 1.52397895264345 0.000320472018090567 0.00540282953575764 GO:0051015 actin filament binding 54/3070 209/18639 0.258373205741627 1.56867041753035 0.000355983564746582 0.00591427373187763 GO:0004679 AMP-activated protein kinase activity 62/3070 248/18639 0.25 1.5178338762215 0.00035980372513324 0.00591427373187763 GO:0008198 ferrous iron binding 12/3070 26/18639 0.461538461538462 2.80215484840892 0.000385773537715823 0.006262866692547 GO:0019903 protein phosphatase binding 40/3070 144/18639 0.277777777777778 1.68648208469055 0.000422543503546828 0.0067761549654156 GO:0035173 histone kinase activity 84/3070 360/18639 0.233333333333333 1.41664495114007 0.000434658582391481 0.00688645826319033 GO:0004842 ubiquitin-protein transferase activity 101/3070 449/18639 0.224944320712695 1.36571244096545 0.000494681637008102 0.00768299594854224 GO:0016755 aminoacyltransferase activity 110/3070 496/18639 0.221774193548387 1.34646553535778 0.000496619509981818 0.00768299594854224 GO:0140996 histone H3 kinase activity 83/3070 357/18639 0.23249299719888 1.41154298853092 0.000527389644446751 0.0080641556098544 GO:0022853 active monoatomic ion transmembrane transporter activity 34/3070 118/18639 0.288135593220339 1.74936785734003 0.000538892461563455 0.00814532858570049 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 7/3070 11/18639 0.636363636363636 3.86357713947291 0.000581324367011766 0.00868683571159627 GO:0048038 quinone binding 9/3070 17/18639 0.529411764705882 3.21423644376317 0.00060226398157485 0.00889861950304413 GO:0141003 histone H2AX kinase activity 82/3070 354/18639 0.231638418079096 1.40635455197924 0.000639086277071413 0.00930547942189969 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 19/3070 54/18639 0.351851851851852 2.13621064060803 0.00065102973902264 0.00930547942189969 GO:0051287 NAD binding 19/3070 54/18639 0.351851851851852 2.13621064060803 0.00065102973902264 0.00930547942189969 GO:0019003 GDP binding 24/3070 75/18639 0.32 1.94282736156352 0.000674143183434894 0.00950152902852731 GO:0019902 phosphatase binding 49/3070 190/18639 0.257894736842105 1.5657654723127 0.0006791967518491 0.00950152902852731 GO:0003712 transcription coregulator activity 109/3070 495/18639 0.22020202020202 1.33692034350015 0.000686748017540973 0.00950603834806715 GO:0042277 peptide binding 61/3070 249/18639 0.244979919678715 1.4873552843295 0.000698840994319024 0.00957266570343247 GO:0032182 ubiquitin-like protein binding 34/3070 120/18639 0.283333333333333 1.72021172638436 0.000750291165165078 0.0101714730122895 GO:0000287 magnesium ion binding 57/3070 230/18639 0.247826086956522 1.50463532077609 0.000762134078141911 0.0102074479503789 GO:0008238 exopeptidase activity 30/3070 102/18639 0.294117647058824 1.78568691320176 0.00076846946546579 0.0102074479503789 GO:0051082 unfolded protein binding 34/3070 121/18639 0.28099173553719 1.70599510054648 0.000881048279353147 0.0115857848734939 GO:0032934 sterol binding 22/3070 68/18639 0.323529411764706 1.96425560452194 0.000941391116674421 0.0122567259250185 GO:0016854 racemase and epimerase activity 9/3070 18/18639 0.5 3.035667752443 0.00102907351610433 0.0132669771929136 GO:0019706 protein-cysteine S-palmitoyltransferase activity 11/3070 25/18639 0.44 2.67138762214984 0.00110585807795549 0.0139827247356872 GO:0019707 protein-cysteine S-acyltransferase activity 11/3070 25/18639 0.44 2.67138762214984 0.00110585807795549 0.0139827247356872 GO:0008514 organic anion transmembrane transporter activity 64/3070 269/18639 0.237918215613383 1.44448130971265 0.00117475180449909 0.0147123678372982 GO:0070008 serine-type exopeptidase activity 7/3070 12/18639 0.583333333333333 3.54161237785016 0.00119668430106908 0.0148456590179797 GO:0061659 ubiquitin-like protein ligase activity 84/3070 372/18639 0.225806451612903 1.37094672690974 0.00124688587528713 0.0153238778131082 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 13/3070 33/18639 0.393939393939394 2.39173822919751 0.00139631128537975 0.016845406791508 GO:0140311 protein sequestering activity 13/3070 33/18639 0.393939393939394 2.39173822919751 0.00139631128537975 0.016845406791508 GO:0017124 SH3 domain binding 32/3070 115/18639 0.278260869565217 1.68941509701175 0.00146552316004066 0.0174240435684048 GO:0019209 kinase activator activity 39/3070 148/18639 0.263513513513513 1.59987895061185 0.00148235733445726 0.0174240435684048 GO:0051539 4 iron, 4 sulfur cluster binding 16/3070 45/18639 0.355555555555556 2.15869706840391 0.00149677267576088 0.0174240435684048 GO:0140318 protein transporter activity 15/3070 41/18639 0.365853658536585 2.22122030666561 0.00149727522679068 0.0174240435684048 GO:0004860 protein kinase inhibitor activity 25/3070 84/18639 0.297619047619048 1.80694509073988 0.00169272035855446 0.0195256778201677 GO:0003925 G protein activity 18/3070 54/18639 0.333333333333333 2.02377850162866 0.00181945241698591 0.0206082966707334 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 18/3070 54/18639 0.333333333333333 2.02377850162866 0.00181945241698591 0.0206082966707334 GO:0042626 ATPase-coupled transmembrane transporter activity 28/3070 98/18639 0.285714285714286 1.73466728711028 0.00183358989389796 0.0206082966707334 GO:0051536 iron-sulfur cluster binding 23/3070 76/18639 0.302631578947368 1.83737785016287 0.00199775761537583 0.0222631463069425 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 33/3070 122/18639 0.270491803278689 1.64224648902654 0.00208169108673563 0.0230035611685492 GO:0015078 proton transmembrane transporter activity 46/3070 185/18639 0.248648648648649 1.50962936878246 0.00216653418167503 0.0234424763779613 GO:0019210 kinase inhibitor activity 26/3070 90/18639 0.288888888888889 1.75394136807818 0.00220912866618946 0.0234424763779613 GO:0005338 nucleotide-sugar transmembrane transporter activity 7/3070 13/18639 0.538461538461538 3.26918065647707 0.0022250261718661 0.0234424763779613 GO:0017154 semaphorin receptor activity 7/3070 13/18639 0.538461538461538 3.26918065647707 0.0022250261718661 0.0234424763779613 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 35/3070 132/18639 0.265151515151515 1.60982380811371 0.00224712251793413 0.0234424763779613 GO:0008239 dipeptidyl-peptidase activity 6/3070 10/18639 0.6 3.6428013029316 0.00228185321397646 0.0234424763779613 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 6/3070 10/18639 0.6 3.6428013029316 0.00228185321397646 0.0234424763779613 GO:0015924 mannosyl-oligosaccharide mannosidase activity 6/3070 10/18639 0.6 3.6428013029316 0.00228185321397646 0.0234424763779613 GO:0045322 unmethylated CpG binding 6/3070 10/18639 0.6 3.6428013029316 0.00228185321397646 0.0234424763779613 GO:0030544 Hsp70 protein binding 17/3070 51/18639 0.333333333333333 2.02377850162866 0.00241049862469554 0.0244005804993417 GO:0051540 metal cluster binding 23/3070 77/18639 0.298701298701299 1.81351580016075 0.00241222468814785 0.0244005804993417 GO:0045296 cadherin binding 75/3070 334/18639 0.224550898203593 1.36332384091751 0.00256226646968096 0.0257204611269501 GO:0032977 membrane insertase activity 8/3070 17/18639 0.470588235294118 2.85709906112282 0.00319796847275967 0.031858549558174 GO:0009055 electron transfer activity 31/3070 116/18639 0.267241379310345 1.6225120745816 0.00340875352214386 0.0332429306423423 GO:0004177 aminopeptidase activity 14/3070 40/18639 0.35 2.1249674267101 0.00342790383810009 0.0332429306423423 GO:0022884 macromolecule transmembrane transporter activity 12/3070 32/18639 0.375 2.27675081433225 0.00343805214247799 0.0332429306423423 GO:0120015 sterol transfer activity 12/3070 32/18639 0.375 2.27675081433225 0.00343805214247799 0.0332429306423423 GO:0016409 palmitoyltransferase activity 13/3070 36/18639 0.361111111111111 2.19242671009772 0.00347077736856528 0.0333143959099514 GO:0004721 phosphoprotein phosphatase activity 43/3070 175/18639 0.245714285714286 1.49181386691484 0.00373630837968321 0.0351358182425395 GO:0003725 double-stranded RNA binding 22/3070 75/18639 0.293333333333333 1.78092508143322 0.00379126596718904 0.0351358182425395 GO:0044183 protein folding chaperone 22/3070 75/18639 0.293333333333333 1.78092508143322 0.00379126596718904 0.0351358182425395 GO:0051018 protein kinase A binding 17/3070 53/18639 0.320754716981132 1.94740950156721 0.00380101257167565 0.0351358182425395 GO:0071933 Arp2/3 complex binding 7/3070 14/18639 0.5 3.035667752443 0.00382074566503066 0.0351358182425395 GO:0140789 histone phosphatase activity 35/3070 136/18639 0.257352941176471 1.56247604905154 0.00382085323854231 0.0351358182425395 GO:0072542 protein phosphatase activator activity 9/3070 21/18639 0.428571428571429 2.60200093066543 0.00388800065565315 0.0355050059873882 GO:0060590 ATPase regulator activity 16/3070 49/18639 0.326530612244898 1.98247689955461 0.00403435375920099 0.036587415126547 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 6/3070 11/18639 0.545454545454545 3.31163754811963 0.0043224878303341 0.0382673373765857 GO:0019107 myristoyltransferase activity 6/3070 11/18639 0.545454545454545 3.31163754811963 0.0043224878303341 0.0382673373765857 GO:0042608 T cell receptor binding 6/3070 11/18639 0.545454545454545 3.31163754811963 0.0043224878303341 0.0382673373765857 GO:0016922 nuclear receptor binding 35/3070 137/18639 0.255474452554745 1.55107111438693 0.00433599488145344 0.0382673373765857 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 20/3070 67/18639 0.298507462686567 1.81233895668239 0.00452455108913228 0.0396652312147263 GO:0043021 ribonucleoprotein complex binding 43/3070 177/18639 0.242937853107345 1.4749572130514 0.00465254183041936 0.0405171689205394 GO:0015485 cholesterol binding 17/3070 54/18639 0.314814814814815 1.91134636264929 0.00471145912923581 0.0406595662231327 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 33/3070 128/18639 0.2578125 1.56526618485342 0.00473073280010593 0.0406595662231327 GO:0001618 virus receptor activity 23/3070 81/18639 0.283950617283951 1.72395946435034 0.00487005489523754 0.0413169173370153 GO:0015101 organic cation transmembrane transporter activity 23/3070 81/18639 0.283950617283951 1.72395946435034 0.00487005489523754 0.0413169173370153 GO:1901682 sulfur compound transmembrane transporter activity 19/3070 63/18639 0.301587301587302 1.83103769194974 0.00492723182317998 0.0413185097839516 GO:0030228 lipoprotein particle receptor activity 8/3070 18/18639 0.444444444444444 2.69837133550489 0.00493308443808395 0.0413185097839516 GO:0061630 ubiquitin protein ligase activity 77/3070 353/18639 0.218130311614731 1.32434230559836 0.00497606429685938 0.0414147123441145 GO:0030145 manganese ion binding 20/3070 68/18639 0.294117647058824 1.78568691320176 0.0054369817264092 0.0449662325171578 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 9/3070 22/18639 0.409090909090909 2.48372816108972 0.00562977168698314 0.0462696860523927 GO:0001221 transcription coregulator binding 30/3070 115/18639 0.260869565217391 1.58382665344852 0.00572126965256547 0.0465554117020062 GO:0140272 exogenous protein binding 23/3070 82/18639 0.280487804878049 1.70293556844363 0.00573534349484792 0.0465554117020062 GO:0043539 protein serine/threonine kinase activator activity 21/3070 73/18639 0.287671232876712 1.74654856989871 0.0059067970131533 0.047652994308568 GO:0050681 nuclear androgen receptor binding 10/3070 26/18639 0.384615384615385 2.33512904034077 0.00599565176329504 0.048074890663006 GO:0015215 nucleotide transmembrane transporter activity 11/3070 30/18639 0.366666666666667 2.22615635179153 0.00611760931676011 0.0487501303466339 GO:0015929 hexosaminidase activity 7/3070 15/18639 0.466666666666667 2.83328990228013 0.00615400884984124 0.0487501303466339 GO:0004197 cysteine-type endopeptidase activity 24/3070 88/18639 0.272727272727273 1.65581877405982 0.00707197669537936 0.0556865230803824 GO:0120013 lipid transfer activity 19/3070 65/18639 0.292307692307692 1.77469807065898 0.00713298117479637 0.055832560981293 GO:0005346 purine ribonucleotide transmembrane transporter activity 8/3070 19/18639 0.421052631578947 2.55635179153094 0.00730547947340892 0.0565100323972514 GO:0015245 fatty acid transmembrane transporter activity 8/3070 19/18639 0.421052631578947 2.55635179153094 0.00730547947340892 0.0565100323972514 GO:0004725 protein tyrosine phosphatase activity 26/3070 98/18639 0.26530612244898 1.61076248088812 0.00765534135080753 0.0588700226684907 GO:0004722 protein serine/threonine phosphatase activity 27/3070 103/18639 0.262135922330097 1.59151513234876 0.00789434588519555 0.0601769285559273 GO:0043274 phospholipase binding 9/3070 23/18639 0.391304347826087 2.37573998017278 0.00791681265412579 0.0601769285559273 GO:0005496 steroid binding 28/3070 108/18639 0.259259259259259 1.57404994571118 0.00810104985935989 0.0611630397822636 GO:0005385 zinc ion transmembrane transporter activity 10/3070 27/18639 0.37037037037037 2.24864277958741 0.00813956803186017 0.0611630397822636 GO:0032266 phosphatidylinositol-3-phosphate binding 15/3070 48/18639 0.3125 1.89729234527687 0.00828880272198554 0.0619305430648351 GO:0016790 thiolester hydrolase activity 14/3070 44/18639 0.318181818181818 1.93178856973645 0.00891233363218837 0.0662131001487441 GO:0003713 transcription coactivator activity 57/3070 256/18639 0.22265625 1.35182079600977 0.0092739703681437 0.0685127586185897 GO:0015179 L-amino acid transmembrane transporter activity 18/3070 62/18639 0.290322580645161 1.7626457917411 0.00936111018942736 0.0686956959942726 GO:0005324 long-chain fatty acid transmembrane transporter activity 7/3070 16/18639 0.4375 2.65620928338762 0.00940321313990043 0.0686956959942726 GO:0030295 protein kinase activator activity 34/3070 139/18639 0.244604316546763 1.48507487169873 0.00982865118748195 0.0714070514449655 GO:0016004 phospholipase activator activity 8/3070 20/18639 0.4 2.4285342019544 0.0104440612726934 0.0754554882428065 GO:0051059 NF-kappaB binding 11/3070 32/18639 0.34375 2.08702157980456 0.0105348012440569 0.0754554882428065 GO:0016853 isomerase activity 42/3070 180/18639 0.233333333333333 1.41664495114007 0.0105580302940505 0.0754554882428065 GO:0036408 histone H3K14 acetyltransferase activity 10/3070 28/18639 0.357142857142857 2.16833410888785 0.0108267203375279 0.0762769740929631 GO:0060229 lipase activator activity 9/3070 24/18639 0.375 2.27675081433225 0.0108469917531438 0.0762769740929631 GO:0140033 acetylation-dependent protein binding 9/3070 24/18639 0.375 2.27675081433225 0.0108469917531438 0.0762769740929631 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 32/3070 130/18639 0.246153846153846 1.49448258581809 0.0109159821853968 0.0763538115627489 GO:0004715 non-membrane spanning protein tyrosine kinase activity 14/3070 45/18639 0.311111111111111 1.88885993485342 0.0110186005303339 0.0766638079226938 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 13/3070 41/18639 0.317073170731707 1.92505759911019 0.0118814416297467 0.081676402006193 GO:0008035 high-density lipoprotein particle binding 6/3070 13/18639 0.461538461538462 2.80215484840892 0.0119253758062274 0.081676402006193 GO:0035325 Toll-like receptor binding 6/3070 13/18639 0.461538461538462 2.80215484840892 0.0119253758062274 0.081676402006193 GO:0043178 alcohol binding 24/3070 92/18639 0.260869565217391 1.58382665344852 0.0125196369995231 0.0853021899190305 GO:0004857 enzyme inhibitor activity 86/3070 416/18639 0.206730769230769 1.25513185918316 0.0132982288831152 0.0901400566046212 GO:0140313 molecular sequestering activity 16/3070 55/18639 0.290909090909091 1.76620669233047 0.0135472907198352 0.0908399647993573 GO:0004659 prenyltransferase activity 7/3070 17/18639 0.411764705882353 2.49996167848247 0.0137468844068989 0.0908399647993573 GO:0008484 sulfuric ester hydrolase activity 7/3070 17/18639 0.411764705882353 2.49996167848247 0.0137468844068989 0.0908399647993573 GO:0070402 NADPH binding 7/3070 17/18639 0.411764705882353 2.49996167848247 0.0137468844068989 0.0908399647993573 GO:0070403 NAD+ binding 7/3070 17/18639 0.411764705882353 2.49996167848247 0.0137468844068989 0.0908399647993573 GO:0008080 N-acetyltransferase activity 19/3070 69/18639 0.27536231884058 1.67181702308455 0.0139241734868056 0.0915514406757465 GO:0010484 histone H3 acetyltransferase activity 10/3070 29/18639 0.344827586206897 2.09356396720207 0.0141356331597476 0.0919547176496356 GO:0051861 glycolipid binding 10/3070 29/18639 0.344827586206897 2.09356396720207 0.0141356331597476 0.0919547176496356 GO:0017025 TBP-class protein binding 9/3070 25/18639 0.36 2.18568078175896 0.0145195143724932 0.0919547176496356 GO:0019211 phosphatase activator activity 9/3070 25/18639 0.36 2.18568078175896 0.0145195143724932 0.0919547176496356 GO:0047617 fatty acyl-CoA hydrolase activity 9/3070 25/18639 0.36 2.18568078175896 0.0145195143724932 0.0919547176496356 GO:0120020 cholesterol transfer activity 9/3070 25/18639 0.36 2.18568078175896 0.0145195143724932 0.0919547176496356 GO:0051879 Hsp90 protein binding 13/3070 42/18639 0.30952380952381 1.87922289436947 0.0146730749433312 0.0919547176496356 GO:0005522 profilin binding 5/3070 10/18639 0.5 3.035667752443 0.0146847838071661 0.0919547176496356 GO:0043422 protein kinase B binding 5/3070 10/18639 0.5 3.035667752443 0.0146847838071661 0.0919547176496356 GO:0070513 death domain binding 5/3070 10/18639 0.5 3.035667752443 0.0146847838071661 0.0919547176496356 GO:0016791 phosphatase activity 59/3070 273/18639 0.216117216117216 1.31212012742957 0.0152462112966606 0.0950178571332163 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 23/3070 89/18639 0.258426966292135 1.56899681586941 0.0159799989926882 0.0986558623257509 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 23/3070 89/18639 0.258426966292135 1.56899681586941 0.0159799989926882 0.0986558623257509 GO:0030246 carbohydrate binding 60/3070 280/18639 0.214285714285714 1.30100046533271 0.0172002973516995 0.102554742057626 GO:0030159 signaling receptor complex adaptor activity 15/3070 52/18639 0.288461538461538 1.75134678025558 0.0178459625649693 0.102554742057626 GO:0004712 protein serine/threonine/tyrosine kinase activity 13/3070 43/18639 0.302325581395349 1.83552003636088 0.0179389121412847 0.102554742057626 GO:0005347 ATP transmembrane transporter activity 6/3070 14/18639 0.428571428571429 2.60200093066543 0.018003848412125 0.102554742057626 GO:0008474 palmitoyl-(protein) hydrolase activity 6/3070 14/18639 0.428571428571429 2.60200093066543 0.018003848412125 0.102554742057626 GO:0034236 protein kinase A catalytic subunit binding 6/3070 14/18639 0.428571428571429 2.60200093066543 0.018003848412125 0.102554742057626 GO:0044548 S100 protein binding 6/3070 14/18639 0.428571428571429 2.60200093066543 0.018003848412125 0.102554742057626 GO:0098599 palmitoyl hydrolase activity 6/3070 14/18639 0.428571428571429 2.60200093066543 0.018003848412125 0.102554742057626 GO:0008235 metalloexopeptidase activity 18/3070 66/18639 0.272727272727273 1.65581877405982 0.0180886437777684 0.102554742057626 GO:0001968 fibronectin binding 10/3070 30/18639 0.333333333333333 2.02377850162866 0.0181446450812412 0.102554742057626 GO:0043995 histone H4K5 acetyltransferase activity 10/3070 30/18639 0.333333333333333 2.02377850162866 0.0181446450812412 0.102554742057626 GO:0043996 histone H4K8 acetyltransferase activity 10/3070 30/18639 0.333333333333333 2.02377850162866 0.0181446450812412 0.102554742057626 GO:0043997 histone H4K12 acetyltransferase activity 10/3070 30/18639 0.333333333333333 2.02377850162866 0.0181446450812412 0.102554742057626 GO:0051721 protein phosphatase 2A binding 10/3070 30/18639 0.333333333333333 2.02377850162866 0.0181446450812412 0.102554742057626 GO:0140793 histone H2AXY142 phosphatase activity 23/3070 90/18639 0.255555555555556 1.55156351791531 0.0182105881953549 0.102554742057626 GO:0015297 antiporter activity 32/3070 135/18639 0.237037037037037 1.43913137893594 0.0187582237118241 0.102554742057626 GO:0015216 purine nucleotide transmembrane transporter activity 9/3070 26/18639 0.346153846153846 2.10161613630669 0.0190321475185393 0.102554742057626 GO:0016289 acyl-CoA hydrolase activity 9/3070 26/18639 0.346153846153846 2.10161613630669 0.0190321475185393 0.102554742057626 GO:0034237 protein kinase A regulatory subunit binding 9/3070 26/18639 0.346153846153846 2.10161613630669 0.0190321475185393 0.102554742057626 GO:0016504 peptidase activator activity 16/3070 57/18639 0.280701754385965 1.7042345276873 0.0190979521680558 0.102554742057626 GO:0035615 clathrin adaptor activity 7/3070 18/18639 0.388888888888889 2.36107491856678 0.0193556662052358 0.102554742057626 GO:0032931 histone H3K56 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0043992 histone H3K9 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0043993 histone H3K18 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0043994 histone H3K23 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0043999 histone H2AK5 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0044012 histone H2AK9 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0044014 histone H2BK5 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0044015 histone H2BK12 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0044016 histone H3K4 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0044017 histone H3K27 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0044018 histone H3K36 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0046972 histone H4K16 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0140908 histone H3K122 acetyltransferase activity 8/3070 22/18639 0.363636363636364 2.20775836541309 0.0195350106436437 0.102554742057626 GO:0042578 phosphoric ester hydrolase activity 75/3070 363/18639 0.206611570247934 1.25440816216653 0.0199095857949023 0.102554742057626 GO:0033192 calmodulin-dependent protein phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0140791 histone H2AXS140 phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:1990439 MAP kinase serine/threonine phosphatase activity 21/3070 81/18639 0.259259259259259 1.57404994571118 0.0199650296325112 0.102554742057626 GO:0050660 flavin adenine dinucleotide binding 22/3070 86/18639 0.255813953488372 1.55313233845921 0.0203671636337293 0.104213308086981 GO:1902936 phosphatidylinositol bisphosphate binding 27/3070 111/18639 0.243243243243243 1.47681133902632 0.0211993241793397 0.107538894955956 GO:0034212 protein N-acetyltransferase activity 15/3070 53/18639 0.283018867924528 1.71830250138283 0.0212028694981594 0.107538894955956 GO:0010485 histone H4 acetyltransferase activity 11/3070 35/18639 0.314285714285714 1.90813401582131 0.0212624431091623 0.107538894955956 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 21/3070 82/18639 0.25609756097561 1.55485421466593 0.0227921550731914 0.114189241775665 GO:0033549 MAP kinase phosphatase activity 21/3070 82/18639 0.25609756097561 1.55485421466593 0.0227921550731914 0.114189241775665 GO:0140030 modification-dependent protein binding 39/3070 173/18639 0.225433526011561 1.36868257046563 0.022837848355133 0.114189241775665 GO:0016411 acylglycerol O-acyltransferase activity 10/3070 31/18639 0.32258064516129 1.95849532415677 0.022930050481647 0.114215971149113 GO:0008526 phosphatidylinositol transfer activity 5/3070 11/18639 0.454545454545455 2.75969795676636 0.0233200304545262 0.114803884803219 GO:0034713 type I transforming growth factor beta receptor binding 5/3070 11/18639 0.454545454545455 2.75969795676636 0.0233200304545262 0.114803884803219 GO:0047676 arachidonate-CoA ligase activity 5/3070 11/18639 0.454545454545455 2.75969795676636 0.0233200304545262 0.114803884803219 GO:0052689 carboxylic ester hydrolase activity 23/3070 92/18639 0.25 1.5178338762215 0.0233972936328993 0.114803884803219 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 12/3070 40/18639 0.3 1.8214006514658 0.0238902876363447 0.115075927625616 GO:0061791 GTPase motor activity 12/3070 40/18639 0.3 1.8214006514658 0.0238902876363447 0.115075927625616 GO:0071949 FAD binding 12/3070 40/18639 0.3 1.8214006514658 0.0238902876363447 0.115075927625616 GO:0140662 ATP-dependent protein folding chaperone 12/3070 40/18639 0.3 1.8214006514658 0.0238902876363447 0.115075927625616 GO:1990606 membrane scission GTPase motor activity 12/3070 40/18639 0.3 1.8214006514658 0.0238902876363447 0.115075927625616 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 18/3070 68/18639 0.264705882352941 1.60711822188159 0.024325995321222 0.116627336954242 GO:0001671 ATPase activator activity 9/3070 27/18639 0.333333333333333 2.02377850162866 0.0244784372618789 0.116627336954242 GO:0008320 protein transmembrane transporter activity 9/3070 27/18639 0.333333333333333 2.02377850162866 0.0244784372618789 0.116627336954242 GO:0000295 adenine nucleotide transmembrane transporter activity 8/3070 23/18639 0.347826086956522 2.11176887126469 0.0257313829047199 0.119581509023468 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 8/3070 23/18639 0.347826086956522 2.11176887126469 0.0257313829047199 0.119581509023468 GO:0042171 lysophosphatidic acid acyltransferase activity 8/3070 23/18639 0.347826086956522 2.11176887126469 0.0257313829047199 0.119581509023468 GO:0044013 histone H2B acetyltransferase activity 8/3070 23/18639 0.347826086956522 2.11176887126469 0.0257313829047199 0.119581509023468 GO:0070577 lysine-acetylated histone binding 8/3070 23/18639 0.347826086956522 2.11176887126469 0.0257313829047199 0.119581509023468 GO:0071617 lysophospholipid acyltransferase activity 8/3070 23/18639 0.347826086956522 2.11176887126469 0.0257313829047199 0.119581509023468 GO:0000774 adenyl-nucleotide exchange factor activity 6/3070 15/18639 0.4 2.4285342019544 0.0259037414536475 0.119581509023468 GO:0005041 low-density lipoprotein particle receptor activity 6/3070 15/18639 0.4 2.4285342019544 0.0259037414536475 0.119581509023468 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 21/3070 83/18639 0.253012048192771 1.5361210313567 0.0259169049974818 0.119581509023468 GO:0016651 oxidoreductase activity, acting on NAD(P)H 22/3070 88/18639 0.25 1.5178338762215 0.0261995859406011 0.120463131160456 GO:0051213 dioxygenase activity 23/3070 93/18639 0.247311827956989 1.50151308185353 0.0263842107236869 0.120889327880308 GO:0019955 cytokine binding 33/3070 144/18639 0.229166666666667 1.39134771986971 0.0274326849468805 0.12525687744843 GO:0032813 tumor necrosis factor receptor superfamily binding 14/3070 50/18639 0.28 1.69997394136808 0.0278645832803582 0.126788674787789 GO:0043425 bHLH transcription factor binding 10/3070 32/18639 0.3125 1.89729234527687 0.0285642546805516 0.128636968852484 GO:0071813 lipoprotein particle binding 10/3070 32/18639 0.3125 1.89729234527687 0.0285642546805516 0.128636968852484 GO:0071814 protein-lipid complex binding 10/3070 32/18639 0.3125 1.89729234527687 0.0285642546805516 0.128636968852484 GO:0001727 lipid kinase activity 12/3070 41/18639 0.292682926829268 1.77697624533249 0.0288594652942474 0.12952285618408 GO:0017018 myosin phosphatase activity 21/3070 84/18639 0.25 1.5178338762215 0.0293572043378789 0.131308584028268 GO:0004713 protein tyrosine kinase activity 32/3070 140/18639 0.228571428571429 1.38773382968823 0.0305311344739688 0.136096412994132 GO:0051019 mitogen-activated protein kinase binding 9/3070 28/18639 0.321428571428571 1.95150069799907 0.0309450400155188 0.137012550910462 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 9/3070 28/18639 0.321428571428571 1.95150069799907 0.0309450400155188 0.137012550910462 GO:0005178 integrin binding 36/3070 161/18639 0.22360248447205 1.35756570295587 0.0311863041895906 0.137541598222439 GO:0038024 cargo receptor activity 17/3070 65/18639 0.261538461538462 1.58788774743172 0.031378311381545 0.137541598222439 GO:0160215 deacylase activity 17/3070 65/18639 0.261538461538462 1.58788774743172 0.031378311381545 0.137541598222439 GO:0140375 immune receptor activity 35/3070 156/18639 0.224358974358974 1.36215860686545 0.0317648681949399 0.138773427496166 GO:0015295 solute:proton symporter activity 8/3070 24/18639 0.333333333333333 2.02377850162866 0.0331735784805079 0.143497551650881 GO:0035035 histone acetyltransferase binding 8/3070 24/18639 0.333333333333333 2.02377850162866 0.0331735784805079 0.143497551650881 GO:0043998 histone H2A acetyltransferase activity 8/3070 24/18639 0.333333333333333 2.02377850162866 0.0331735784805079 0.143497551650881 GO:0005319 lipid transporter activity 39/3070 178/18639 0.219101123595506 1.33023643084581 0.0345928716907253 0.148449308926505 GO:0035014 phosphatidylinositol 3-kinase regulator activity 5/3070 12/18639 0.416666666666667 2.52972312703583 0.0346569869509027 0.148449308926505 GO:0035497 cAMP response element binding 5/3070 12/18639 0.416666666666667 2.52972312703583 0.0346569869509027 0.148449308926505 GO:0016408 C-acyltransferase activity 7/3070 20/18639 0.35 2.1249674267101 0.0349684928513213 0.149291280782306 GO:0071889 14-3-3 protein binding 10/3070 33/18639 0.303030303030303 1.83979863784424 0.0351140083398147 0.149291280782306 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 16/3070 61/18639 0.262295081967213 1.59248144390452 0.0351941422376538 0.149291280782306 GO:0000062 fatty-acyl-CoA binding 6/3070 16/18639 0.375 2.27675081433225 0.0358040584418958 0.149467736035216 GO:0004707 MAP kinase activity 6/3070 16/18639 0.375 2.27675081433225 0.0358040584418958 0.149467736035216 GO:0016722 oxidoreductase activity, acting on metal ions 6/3070 16/18639 0.375 2.27675081433225 0.0358040584418958 0.149467736035216 GO:0022858 alanine transmembrane transporter activity 6/3070 16/18639 0.375 2.27675081433225 0.0358040584418958 0.149467736035216 GO:0034450 ubiquitin-ubiquitin ligase activity 6/3070 16/18639 0.375 2.27675081433225 0.0358040584418958 0.149467736035216 GO:0001784 phosphotyrosine residue binding 13/3070 47/18639 0.276595744680851 1.67930556518123 0.0366313793425294 0.151956668250556 GO:0061733 protein-lysine-acetyltransferase activity 13/3070 47/18639 0.276595744680851 1.67930556518123 0.0366313793425294 0.151956668250556 GO:0005080 protein kinase C binding 14/3070 52/18639 0.269230769230769 1.63459032823854 0.0382631187060706 0.15775605647137 GO:0043531 ADP binding 11/3070 38/18639 0.289473684210526 1.75749185667752 0.0384004926428063 0.15775605647137 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 9/3070 29/18639 0.310344827586207 1.88420757048186 0.0385092731006159 0.15775605647137 GO:0097472 cyclin-dependent protein kinase activity 9/3070 29/18639 0.310344827586207 1.88420757048186 0.0385092731006159 0.15775605647137 GO:0043022 ribosome binding 26/3070 112/18639 0.232142857142857 1.40941717077711 0.0400862538571075 0.16370628516179 GO:0038187 pattern recognition receptor activity 13/3070 48/18639 0.270833333333333 1.64432003257329 0.042917503959006 0.174726061009575 GO:0140296 general transcription initiation factor binding 14/3070 53/18639 0.264150943396226 1.60374900129064 0.0443873107294233 0.180152202497505 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 7/3070 21/18639 0.333333333333333 2.02377850162866 0.0452134592200073 0.181267374616798 GO:0005123 death receptor binding 7/3070 21/18639 0.333333333333333 2.02377850162866 0.0452134592200073 0.181267374616798 GO:0051010 microtubule plus-end binding 7/3070 21/18639 0.333333333333333 2.02377850162866 0.0452134592200073 0.181267374616798 GO:0140312 cargo adaptor activity 7/3070 21/18639 0.333333333333333 2.02377850162866 0.0452134592200073 0.181267374616798 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 15/3070 58/18639 0.258620689655172 1.57017297540155 0.0454552941687131 0.181683014686498 GO:0035591 signaling adaptor activity 29/3070 129/18639 0.224806201550388 1.36487387319142 0.0461039780361048 0.18371736702266 GO:0051219 phosphoprotein binding 22/3070 93/18639 0.236559139784946 1.43622990438163 0.046278868976066 0.18385713807712 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 6/3070 17/18639 0.352941176470588 2.14282429584212 0.0478352442791667 0.186656813730279 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 6/3070 17/18639 0.352941176470588 2.14282429584212 0.0478352442791667 0.186656813730279 GO:0005092 GDP-dissociation inhibitor activity 6/3070 17/18639 0.352941176470588 2.14282429584212 0.0478352442791667 0.186656813730279 GO:0015278 intracellularly gated calcium channel activity 6/3070 17/18639 0.352941176470588 2.14282429584212 0.0478352442791667 0.186656813730279 GO:0030169 low-density lipoprotein particle binding 6/3070 17/18639 0.352941176470588 2.14282429584212 0.0478352442791667 0.186656813730279 GO:1901567 fatty acid derivative binding 6/3070 17/18639 0.352941176470588 2.14282429584212 0.0478352442791667 0.186656813730279 GO:0005035 death receptor activity 5/3070 13/18639 0.384615384615385 2.33512904034077 0.0488642439163247 0.18954714085536 GO:0089720 caspase binding 5/3070 13/18639 0.384615384615385 2.33512904034077 0.0488642439163247 0.18954714085536 GO:0001222 transcription corepressor binding 13/3070 49/18639 0.26530612244898 1.61076248088812 0.0499207965767491 0.193076022054191 GO:0050661 NADP binding 14/3070 54/18639 0.259259259259259 1.57404994571118 0.0511676308796728 0.196824410633973 GO:0016229 steroid dehydrogenase activity 10/3070 35/18639 0.285714285714286 1.73466728711028 0.0511893144006227 0.196824410633973 GO:0016410 N-acyltransferase activity 22/3070 94/18639 0.234042553191489 1.42095086284566 0.0513587327825008 0.196900097985389 GO:0005160 transforming growth factor beta receptor binding 8/3070 26/18639 0.307692307692308 1.86810323227261 0.0521385456219943 0.198156611251221 GO:0043548 phosphatidylinositol 3-kinase binding 8/3070 26/18639 0.307692307692308 1.86810323227261 0.0521385456219943 0.198156611251221 GO:0070006 metalloaminopeptidase activity 8/3070 26/18639 0.307692307692308 1.86810323227261 0.0521385456219943 0.198156611251221 GO:0002039 p53 binding 17/3070 69/18639 0.246376811594203 1.49583628381249 0.0527581267795709 0.19993353520212 GO:0015291 secondary active transmembrane transporter activity 58/3070 287/18639 0.202090592334495 1.22695978844386 0.0532216681227261 0.201110613739612 GO:0015036 disulfide oxidoreductase activity 11/3070 40/18639 0.275 1.66961726384365 0.0541033426410297 0.203856434306458 GO:0016878 acid-thiol ligase activity 9/3070 31/18639 0.290322580645161 1.7626457917411 0.0571807109629332 0.213675303458347 GO:0050321 tau-protein kinase activity 7/3070 22/18639 0.318181818181818 1.93178856973645 0.0571967352223104 0.213675303458347 GO:0061133 endopeptidase activator activity 7/3070 22/18639 0.318181818181818 1.93178856973645 0.0571967352223104 0.213675303458347 GO:0008374 O-acyltransferase activity 14/3070 55/18639 0.254545454545455 1.54543085578916 0.0586293866191086 0.218406921824725 GO:0034185 apolipoprotein binding 6/3070 18/18639 0.333333333333333 2.02377850162866 0.0620750333161322 0.228651733363344 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 6/3070 18/18639 0.333333333333333 2.02377850162866 0.0620750333161322 0.228651733363344 GO:0070064 proline-rich region binding 6/3070 18/18639 0.333333333333333 2.02377850162866 0.0620750333161322 0.228651733363344 GO:1990381 ubiquitin-specific protease binding 6/3070 18/18639 0.333333333333333 2.02377850162866 0.0620750333161322 0.228651733363344 GO:0015175 neutral L-amino acid transmembrane transporter activity 11/3070 41/18639 0.268292682926829 1.62889489155478 0.0633594310015164 0.232730870857525 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 8/3070 27/18639 0.296296296296296 1.79891422366992 0.0637849070367798 0.233641094020516 GO:0004180 carboxypeptidase activity 12/3070 46/18639 0.260869565217391 1.58382665344852 0.0650918319428495 0.237380467865184 GO:0005545 1-phosphatidylinositol binding 5/3070 14/18639 0.357142857142857 2.16833410888785 0.0660089080853246 0.237380467865184 GO:0008191 metalloendopeptidase inhibitor activity 5/3070 14/18639 0.357142857142857 2.16833410888785 0.0660089080853246 0.237380467865184 GO:0016530 metallochaperone activity 5/3070 14/18639 0.357142857142857 2.16833410888785 0.0660089080853246 0.237380467865184 GO:0016830 carbon-carbon lyase activity 13/3070 51/18639 0.254901960784314 1.54759532477486 0.0661900954327774 0.237380467865184 GO:0004090 carbonyl reductase (NADPH) activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0005031 tumor necrosis factor receptor activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0005381 iron ion transmembrane transporter activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0015279 store-operated calcium channel activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0015658 branched-chain amino acid transmembrane transporter activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0016303 1-phosphatidylinositol-3-kinase activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0031957 very long-chain fatty acid-CoA ligase activity 4/3070 10/18639 0.4 2.4285342019544 0.0671524973732686 0.237380467865184 GO:0140103 catalytic activity, acting on a glycoprotein 7/3070 23/18639 0.304347826086957 1.84779776235661 0.0709628268612562 0.249508335087037 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 7/3070 23/18639 0.304347826086957 1.84779776235661 0.0709628268612562 0.249508335087037 GO:0043394 proteoglycan binding 10/3070 37/18639 0.27027027027027 1.64090148780703 0.0715200108796498 0.250796838151305 GO:0004402 histone acetyltransferase activity 11/3070 42/18639 0.261904761904762 1.59011167985109 0.0735878021381593 0.256678938492518 GO:0048487 beta-tubulin binding 11/3070 42/18639 0.261904761904762 1.59011167985109 0.0735878021381593 0.256678938492518 GO:0051537 2 iron, 2 sulfur cluster binding 8/3070 28/18639 0.285714285714286 1.73466728711028 0.0769208538452842 0.266888978381395 GO:0141052 histone H3 demethylase activity 8/3070 28/18639 0.285714285714286 1.73466728711028 0.0769208538452842 0.266888978381395 GO:0003756 protein disulfide isomerase activity 6/3070 19/18639 0.315789473684211 1.91726384364821 0.078547383247208 0.269686185300466 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 6/3070 19/18639 0.315789473684211 1.91726384364821 0.078547383247208 0.269686185300466 GO:0097001 ceramide binding 6/3070 19/18639 0.315789473684211 1.91726384364821 0.078547383247208 0.269686185300466 GO:0120227 acyl-CoA binding 6/3070 19/18639 0.315789473684211 1.91726384364821 0.078547383247208 0.269686185300466 GO:0001540 amyloid-beta binding 19/3070 83/18639 0.228915662650602 1.38982379027511 0.0800895528388859 0.274265005164414 GO:0042887 amide transmembrane transporter activity 10/3070 38/18639 0.263157894736842 1.59771986970684 0.083348410249951 0.284683531113469 GO:0005507 copper ion binding 15/3070 63/18639 0.238095238095238 1.4455560725919 0.0846498320803377 0.286508509348176 GO:0008375 acetylglucosaminyltransferase activity 11/3070 43/18639 0.255813953488372 1.55313233845921 0.0848043190667776 0.286508509348176 GO:0140693 molecular condensate scaffold activity 12/3070 48/18639 0.25 1.5178338762215 0.0854937672214198 0.286508509348176 GO:0016860 intramolecular oxidoreductase activity 13/3070 53/18639 0.245283018867925 1.48919550119845 0.0856104151823297 0.286508509348176 GO:0004467 long-chain fatty acid-CoA ligase activity 5/3070 15/18639 0.333333333333333 2.02377850162866 0.0860614914011631 0.286508509348176 GO:0047372 monoacylglycerol lipase activity 5/3070 15/18639 0.333333333333333 2.02377850162866 0.0860614914011631 0.286508509348176 GO:0050700 CARD domain binding 5/3070 15/18639 0.333333333333333 2.02377850162866 0.0860614914011631 0.286508509348176 GO:0050780 dopamine receptor binding 5/3070 15/18639 0.333333333333333 2.02377850162866 0.0860614914011631 0.286508509348176 GO:0061578 K63-linked deubiquitinase activity 5/3070 15/18639 0.333333333333333 2.02377850162866 0.0860614914011631 0.286508509348176 GO:0140776 protein-containing complex destabilizing activity 5/3070 15/18639 0.333333333333333 2.02377850162866 0.0860614914011631 0.286508509348176 GO:0004622 lysophospholipase activity 7/3070 24/18639 0.291666666666667 1.77080618892508 0.0865231056062702 0.286594165925051 GO:0050431 transforming growth factor beta binding 7/3070 24/18639 0.291666666666667 1.77080618892508 0.0865231056062702 0.286594165925051 GO:0033218 amide binding 49/3070 247/18639 0.198380566801619 1.20443497870208 0.0907109932797119 0.296436435317332 GO:0048029 monosaccharide binding 17/3070 74/18639 0.22972972972973 1.39476626463597 0.091580466566154 0.296436435317332 GO:0000099 sulfur amino acid transmembrane transporter activity 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0005225 volume-sensitive anion channel activity 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0008172 S-methyltransferase activity 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0008199 ferric iron binding 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0008432 JUN kinase binding 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0015217 ADP transmembrane transporter activity 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0019206 nucleoside kinase activity 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0019864 IgG binding 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0032794 GTPase activating protein binding 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0140031 phosphorylation-dependent protein binding 4/3070 11/18639 0.363636363636364 2.20775836541309 0.0921996213268357 0.296436435317332 GO:0090482 vitamin transmembrane transporter activity 9/3070 34/18639 0.264705882352941 1.60711822188159 0.0946096053750434 0.303443002605322 GO:0001786 phosphatidylserine binding 14/3070 59/18639 0.23728813559322 1.44065588251532 0.0956504949003644 0.30455302855685 GO:0031593 polyubiquitin modification-dependent protein binding 14/3070 59/18639 0.23728813559322 1.44065588251532 0.0956504949003644 0.30455302855685 GO:0045309 protein phosphorylated amino acid binding 14/3070 59/18639 0.23728813559322 1.44065588251532 0.0956504949003644 0.30455302855685 GO:0001223 transcription coactivator binding 11/3070 44/18639 0.25 1.5178338762215 0.0970155701200471 0.304827163804163 GO:0003954 NADH dehydrogenase activity 11/3070 44/18639 0.25 1.5178338762215 0.0970155701200471 0.304827163804163 GO:0019205 nucleobase-containing compound kinase activity 11/3070 44/18639 0.25 1.5178338762215 0.0970155701200471 0.304827163804163 GO:0016505 peptidase activator activity involved in apoptotic process 6/3070 20/18639 0.3 1.8214006514658 0.0972240505597308 0.304827163804163 GO:0030742 GTP-dependent protein binding 6/3070 20/18639 0.3 1.8214006514658 0.0972240505597308 0.304827163804163 GO:0042288 MHC class I protein binding 6/3070 20/18639 0.3 1.8214006514658 0.0972240505597308 0.304827163804163 GO:0003714 transcription corepressor activity 41/3070 204/18639 0.200980392156863 1.22021939068787 0.0973592462340291 0.304827163804163 GO:0019208 phosphatase regulator activity 25/3070 117/18639 0.213675213675214 1.29729391130043 0.0982872986765626 0.306274402274123 GO:1990782 protein tyrosine kinase binding 25/3070 117/18639 0.213675213675214 1.29729391130043 0.0982872986765626 0.306274402274123 GO:0046943 carboxylic acid transmembrane transporter activity 38/3070 188/18639 0.202127659574468 1.22718483609398 0.100429305845852 0.312209307771385 GO:0072341 modified amino acid binding 20/3070 91/18639 0.21978021978022 1.3343594516233 0.103405415915018 0.319091288988667 GO:0019888 protein phosphatase regulator activity 23/3070 107/18639 0.214953271028037 1.30505342628391 0.103835968337527 0.319091288988667 GO:0004709 MAP kinase kinase kinase activity 7/3070 25/18639 0.28 1.69997394136808 0.103856328279201 0.319091288988667 GO:0015662 P-type ion transporter activity 7/3070 25/18639 0.28 1.69997394136808 0.103856328279201 0.319091288988667 GO:0140358 P-type transmembrane transporter activity 7/3070 25/18639 0.28 1.69997394136808 0.103856328279201 0.319091288988667 GO:0005342 organic acid transmembrane transporter activity 38/3070 189/18639 0.201058201058201 1.22069179463316 0.106558290602803 0.324007012510285 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 14/3070 60/18639 0.233333333333333 1.41664495114007 0.106748411722192 0.324007012510285 GO:0001965 G-protein alpha-subunit binding 8/3070 30/18639 0.266666666666667 1.61902280130293 0.107669061045348 0.324007012510285 GO:0016769 transferase activity, transferring nitrogenous groups 8/3070 30/18639 0.266666666666667 1.61902280130293 0.107669061045348 0.324007012510285 GO:0031210 phosphatidylcholine binding 8/3070 30/18639 0.266666666666667 1.61902280130293 0.107669061045348 0.324007012510285 GO:0032452 histone demethylase activity 8/3070 30/18639 0.266666666666667 1.61902280130293 0.107669061045348 0.324007012510285 GO:0005521 lamin binding 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0008142 oxysterol binding 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0055102 lipase inhibitor activity 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0070411 I-SMAD binding 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0140327 flippase activity 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0140328 floppase activity 5/3070 16/18639 0.3125 1.89729234527687 0.108905779109921 0.324007012510285 GO:0141110 transporter inhibitor activity 11/3070 45/18639 0.244444444444444 1.48410423452769 0.110218701638637 0.327172895383313 GO:0005516 calmodulin binding 41/3070 207/18639 0.198067632850242 1.20253505169239 0.115252007674719 0.341343220928503 GO:0010314 phosphatidylinositol-5-phosphate binding 6/3070 21/18639 0.285714285714286 1.73466728711028 0.11802828709562 0.343887183809118 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 6/3070 21/18639 0.285714285714286 1.73466728711028 0.11802828709562 0.343887183809118 GO:0015085 calcium ion transmembrane transporter activity 30/3070 147/18639 0.204081632653061 1.23904806222163 0.120455298480387 0.343887183809118 GO:0003995 acyl-CoA dehydrogenase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0004300 enoyl-CoA hydratase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0005095 GTPase inhibitor activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0015368 calcium:monoatomic cation antiporter activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0016423 tRNA (guanine) methyltransferase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0034452 dynactin binding 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0035259 nuclear glucocorticoid receptor binding 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:1990459 transferrin receptor binding 4/3070 12/18639 0.333333333333333 2.02377850162866 0.120970938514802 0.343887183809118 GO:0004620 phospholipase activity 23/3070 109/18639 0.211009174311927 1.28110749185668 0.121200509513264 0.343887183809118 GO:0005048 signal sequence binding 12/3070 51/18639 0.235294117647059 1.42854953056141 0.122774643437577 0.343887183809118 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 7/3070 26/18639 0.269230769230769 1.63459032823854 0.12291024820554 0.343887183809118 GO:0050750 low-density lipoprotein particle receptor binding 7/3070 26/18639 0.269230769230769 1.63459032823854 0.12291024820554 0.343887183809118 GO:0051139 metal cation:proton antiporter activity 7/3070 26/18639 0.269230769230769 1.63459032823854 0.12291024820554 0.343887183809118 GO:0052742 phosphatidylinositol kinase activity 7/3070 26/18639 0.269230769230769 1.63459032823854 0.12291024820554 0.343887183809118 GO:0097602 cullin family protein binding 7/3070 26/18639 0.269230769230769 1.63459032823854 0.12291024820554 0.343887183809118 GO:0120014 phospholipid transfer activity 7/3070 26/18639 0.269230769230769 1.63459032823854 0.12291024820554 0.343887183809118 GO:0005164 tumor necrosis factor receptor binding 8/3070 31/18639 0.258064516129032 1.56679625932542 0.125230226291406 0.346049549486894 GO:0070325 lipoprotein particle receptor binding 8/3070 31/18639 0.258064516129032 1.56679625932542 0.125230226291406 0.346049549486894 GO:0072349 modified amino acid transmembrane transporter activity 8/3070 31/18639 0.258064516129032 1.56679625932542 0.125230226291406 0.346049549486894 GO:0140457 protein demethylase activity 8/3070 31/18639 0.258064516129032 1.56679625932542 0.125230226291406 0.346049549486894 GO:0008137 NADH dehydrogenase (ubiquinone) activity 10/3070 41/18639 0.24390243902439 1.48081353777707 0.125525197798668 0.346049549486894 GO:0016877 ligase activity, forming carbon-sulfur bonds 10/3070 41/18639 0.24390243902439 1.48081353777707 0.125525197798668 0.346049549486894 GO:0042287 MHC protein binding 10/3070 41/18639 0.24390243902439 1.48081353777707 0.125525197798668 0.346049549486894 GO:0004033 aldo-keto reductase (NADPH) activity 9/3070 36/18639 0.25 1.5178338762215 0.125917467835225 0.346404749379333 GO:0061134 peptidase regulator activity 44/3070 226/18639 0.194690265486726 1.18202992130524 0.129688717753563 0.356034788822413 GO:0008234 cysteine-type peptidase activity 37/3070 187/18639 0.197860962566845 1.201280287063 0.130376431015659 0.356434525541771 GO:0031406 carboxylic acid binding 37/3070 187/18639 0.197860962566845 1.201280287063 0.130376431015659 0.356434525541771 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 5/3070 17/18639 0.294117647058824 1.78568691320176 0.134351835289402 0.362777542927235 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 5/3070 17/18639 0.294117647058824 1.78568691320176 0.134351835289402 0.362777542927235 GO:0016805 dipeptidase activity 5/3070 17/18639 0.294117647058824 1.78568691320176 0.134351835289402 0.362777542927235 GO:0019198 transmembrane receptor protein phosphatase activity 5/3070 17/18639 0.294117647058824 1.78568691320176 0.134351835289402 0.362777542927235 GO:0036041 long-chain fatty acid binding 5/3070 17/18639 0.294117647058824 1.78568691320176 0.134351835289402 0.362777542927235 GO:0046965 nuclear retinoid X receptor binding 5/3070 17/18639 0.294117647058824 1.78568691320176 0.134351835289402 0.362777542927235 GO:0005504 fatty acid binding 11/3070 47/18639 0.234042553191489 1.42095086284566 0.139542238719873 0.375251623551397 GO:0043495 protein-membrane adaptor activity 11/3070 47/18639 0.234042553191489 1.42095086284566 0.139542238719873 0.375251623551397 GO:0005548 phospholipid transporter activity 15/3070 68/18639 0.220588235294118 1.33926518490132 0.140635859168218 0.376432432008672 GO:0016881 acid-amino acid ligase activity 6/3070 22/18639 0.272727272727273 1.65581877405982 0.140840119048111 0.376432432008672 GO:0031683 G-protein beta/gamma-subunit complex binding 6/3070 22/18639 0.272727272727273 1.65581877405982 0.140840119048111 0.376432432008672 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 7/3070 27/18639 0.259259259259259 1.57404994571118 0.143604117614607 0.38304140905316 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 8/3070 32/18639 0.25 1.5178338762215 0.14418081681334 0.383801162165065 GO:0043177 organic acid binding 37/3070 189/18639 0.195767195767196 1.18856832635334 0.145298537882124 0.385995105686855 GO:0031490 chromatin DNA binding 26/3070 128/18639 0.203125 1.23324002442997 0.145813601877626 0.386582432397335 GO:0008237 metallopeptidase activity 36/3070 184/18639 0.195652173913043 1.18786999008639 0.149966019954097 0.396791380763858 GO:0035673 oligopeptide transmembrane transporter activity 4/3070 13/18639 0.307692307692308 1.86810323227261 0.153018358336348 0.400038054099995 GO:0043560 insulin receptor substrate binding 4/3070 13/18639 0.307692307692308 1.86810323227261 0.153018358336348 0.400038054099995 GO:0046974 histone H3K9 methyltransferase activity 4/3070 13/18639 0.307692307692308 1.86810323227261 0.153018358336348 0.400038054099995 GO:0051011 microtubule minus-end binding 4/3070 13/18639 0.307692307692308 1.86810323227261 0.153018358336348 0.400038054099995 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/3070 13/18639 0.307692307692308 1.86810323227261 0.153018358336348 0.400038054099995 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 4/3070 13/18639 0.307692307692308 1.86810323227261 0.153018358336348 0.400038054099995 GO:0005126 cytokine receptor binding 52/3070 275/18639 0.189090909090909 1.14803435001481 0.154750340893939 0.403763290229225 GO:0015171 amino acid transmembrane transporter activity 21/3070 102/18639 0.205882352941176 1.24998083924123 0.160561125589617 0.418094812178904 GO:0004706 JUN kinase kinase kinase activity 5/3070 18/18639 0.277777777777778 1.68648208469055 0.162150605279121 0.418915610888103 GO:0015172 acidic amino acid transmembrane transporter activity 5/3070 18/18639 0.277777777777778 1.68648208469055 0.162150605279121 0.418915610888103 GO:0032393 MHC class I receptor activity 5/3070 18/18639 0.277777777777778 1.68648208469055 0.162150605279121 0.418915610888103 GO:0050811 GABA receptor binding 5/3070 18/18639 0.277777777777778 1.68648208469055 0.162150605279121 0.418915610888103 GO:0004879 nuclear receptor activity 13/3070 59/18639 0.220338983050847 1.33775189090708 0.163102014216544 0.420547350381872 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 18/3070 86/18639 0.209302325581395 1.27074464055753 0.164792290434413 0.422594254331789 GO:0016298 lipase activity 26/3070 130/18639 0.2 1.2142671009772 0.165420273371525 0.422594254331789 GO:0004602 glutathione peroxidase activity 6/3070 23/18639 0.260869565217391 1.58382665344852 0.165502692761119 0.422594254331789 GO:0005158 insulin receptor binding 6/3070 23/18639 0.260869565217391 1.58382665344852 0.165502692761119 0.422594254331789 GO:0008171 O-methyltransferase activity 6/3070 23/18639 0.260869565217391 1.58382665344852 0.165502692761119 0.422594254331789 GO:0008028 monocarboxylic acid transmembrane transporter activity 15/3070 70/18639 0.214285714285714 1.30100046533271 0.167674096099396 0.426482468802138 GO:0097110 scaffold protein binding 15/3070 70/18639 0.214285714285714 1.30100046533271 0.167674096099396 0.426482468802138 GO:0016779 nucleotidyltransferase activity 27/3070 136/18639 0.198529411764706 1.20533866641119 0.169933389560077 0.431394608632241 GO:0030971 receptor tyrosine kinase binding 17/3070 81/18639 0.209876543209877 1.27423090843286 0.170329709834671 0.431567569234283 GO:0016248 channel inhibitor activity 10/3070 44/18639 0.227272727272727 1.37984897838318 0.177248325214222 0.448233745493659 GO:0016757 glycosyltransferase activity 50/3070 267/18639 0.187265917602996 1.13695421439813 0.178530240823645 0.45014611654416 GO:0098531 ligand-modulated transcription factor activity 13/3070 60/18639 0.216666666666667 1.31545602605863 0.178689180863918 0.45014611654416 GO:0035401 histone H3Y41 kinase activity 23/3070 115/18639 0.2 1.2142671009772 0.183138030780058 0.459592577243848 GO:0140801 histone H2AXY142 kinase activity 23/3070 115/18639 0.2 1.2142671009772 0.183138030780058 0.459592577243848 GO:0030332 cyclin binding 8/3070 34/18639 0.235294117647059 1.42854953056141 0.185933911035144 0.46483477758786 GO:0052866 phosphatidylinositol phosphate phosphatase activity 8/3070 34/18639 0.235294117647059 1.42854953056141 0.185933911035144 0.46483477758786 GO:0004065 arylsulfatase activity 4/3070 14/18639 0.285714285714286 1.73466728711028 0.187822138436757 0.466011532159124 GO:0004705 JUN kinase activity 4/3070 14/18639 0.285714285714286 1.73466728711028 0.187822138436757 0.466011532159124 GO:0061665 SUMO ligase activity 4/3070 14/18639 0.285714285714286 1.73466728711028 0.187822138436757 0.466011532159124 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 4/3070 14/18639 0.285714285714286 1.73466728711028 0.187822138436757 0.466011532159124 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 7/3070 29/18639 0.241379310344828 1.46549477704145 0.189465792501104 0.468322400637126 GO:0099604 ligand-gated calcium channel activity 7/3070 29/18639 0.241379310344828 1.46549477704145 0.189465792501104 0.468322400637126 GO:0005315 phosphate transmembrane transporter activity 6/3070 24/18639 0.25 1.5178338762215 0.191829221812735 0.472830902628204 GO:1990380 K48-linked deubiquitinase activity 5/3070 19/18639 0.263157894736842 1.59771986970684 0.192008898861947 0.472830902628204 GO:0061135 endopeptidase regulator activity 35/3070 184/18639 0.190217391304348 1.15487360147288 0.199218089270807 0.489666892319834 GO:0030170 pyridoxal phosphate binding 12/3070 56/18639 0.214285714285714 1.30100046533271 0.201813054814514 0.492192231391543 GO:0170055 lipid transmembrane transporter activity 12/3070 56/18639 0.214285714285714 1.30100046533271 0.201813054814514 0.492192231391543 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 9/3070 40/18639 0.225 1.36605048859935 0.202491252610513 0.492192231391543 GO:0030331 nuclear estrogen receptor binding 9/3070 40/18639 0.225 1.36605048859935 0.202491252610513 0.492192231391543 GO:0032451 demethylase activity 9/3070 40/18639 0.225 1.36605048859935 0.202491252610513 0.492192231391543 GO:0050997 quaternary ammonium group binding 9/3070 40/18639 0.225 1.36605048859935 0.202491252610513 0.492192231391543 GO:0061631 ubiquitin conjugating enzyme activity 8/3070 35/18639 0.228571428571429 1.38773382968823 0.208539601387199 0.505958626981858 GO:0008106 alcohol dehydrogenase (NADP+) activity 7/3070 30/18639 0.233333333333333 1.41664495114007 0.214360449900681 0.507983167118857 GO:0030291 protein serine/threonine kinase inhibitor activity 10/3070 46/18639 0.217391304347826 1.31985554454043 0.216399150158419 0.507983167118857 GO:0001094 TFIID-class transcription factor complex binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0004382 GDP phosphatase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0005131 growth hormone receptor binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0005345 purine nucleobase transmembrane transporter activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0008140 cAMP response element binding protein binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0016427 tRNA (cytidine) methyltransferase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0016783 sulfurtransferase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0016868 intramolecular phosphotransferase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0030957 Tat protein binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0031419 cobalamin binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0042975 peroxisome proliferator activated receptor binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0043295 glutathione binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0050308 sugar-phosphatase activity 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:1990763 arrestin family protein binding 3/3070 10/18639 0.3 1.8214006514658 0.21928907126665 0.507983167118857 GO:0003707 nuclear steroid receptor activity 6/3070 25/18639 0.24 1.45712052117264 0.219610135560167 0.507983167118857 GO:0008139 nuclear localization sequence binding 6/3070 25/18639 0.24 1.45712052117264 0.219610135560167 0.507983167118857 GO:0015645 fatty acid ligase activity 6/3070 25/18639 0.24 1.45712052117264 0.219610135560167 0.507983167118857 GO:0042974 nuclear retinoic acid receptor binding 6/3070 25/18639 0.24 1.45712052117264 0.219610135560167 0.507983167118857 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 6/3070 25/18639 0.24 1.45712052117264 0.219610135560167 0.507983167118857 GO:0120515 fatty acid-CoA ligase activity 6/3070 25/18639 0.24 1.45712052117264 0.219610135560167 0.507983167118857 GO:0070279 vitamin B6 binding 12/3070 57/18639 0.210526315789474 1.27817589576547 0.219861497285891 0.507983167118857 GO:0033293 monocarboxylic acid binding 16/3070 79/18639 0.20253164556962 1.22963757060982 0.220365026158219 0.507983167118857 GO:0001614 purinergic nucleotide receptor activity 5/3070 20/18639 0.25 1.5178338762215 0.223603848296019 0.507983167118857 GO:0016502 nucleotide receptor activity 5/3070 20/18639 0.25 1.5178338762215 0.223603848296019 0.507983167118857 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 5/3070 20/18639 0.25 1.5178338762215 0.223603848296019 0.507983167118857 GO:0031418 L-ascorbic acid binding 5/3070 20/18639 0.25 1.5178338762215 0.223603848296019 0.507983167118857 GO:0052745 inositol phosphate phosphatase activity 5/3070 20/18639 0.25 1.5178338762215 0.223603848296019 0.507983167118857 GO:0061608 nuclear import signal receptor activity 5/3070 20/18639 0.25 1.5178338762215 0.223603848296019 0.507983167118857 GO:0061650 ubiquitin-like protein conjugating enzyme activity 9/3070 41/18639 0.219512195121951 1.33273218399936 0.224137955526345 0.507983167118857 GO:0140828 metal cation:monoatomic cation antiporter activity 9/3070 41/18639 0.219512195121951 1.33273218399936 0.224137955526345 0.507983167118857 GO:0008242 omega peptidase activity 4/3070 15/18639 0.266666666666667 1.61902280130293 0.224826010086064 0.507983167118857 GO:0017081 chloride channel regulator activity 4/3070 15/18639 0.266666666666667 1.61902280130293 0.224826010086064 0.507983167118857 GO:0120283 protein serine/threonine kinase binding 4/3070 15/18639 0.266666666666667 1.61902280130293 0.224826010086064 0.507983167118857 GO:0141050 histone H3K deacetylase activity 4/3070 15/18639 0.266666666666667 1.61902280130293 0.224826010086064 0.507983167118857 GO:0141051 histone H4K deacetylase activity 4/3070 15/18639 0.266666666666667 1.61902280130293 0.224826010086064 0.507983167118857 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 11/3070 52/18639 0.211538461538462 1.28432097218742 0.228272157556413 0.514884883682133 GO:0004190 aspartic-type endopeptidase activity 8/3070 36/18639 0.222222222222222 1.34918566775244 0.232145925259192 0.52108509165641 GO:0004869 cysteine-type endopeptidase inhibitor activity 8/3070 36/18639 0.222222222222222 1.34918566775244 0.232145925259192 0.52108509165641 GO:0044325 transmembrane transporter binding 26/3070 136/18639 0.191176470588235 1.16069649358115 0.232209782289473 0.52108509165641 GO:0000049 tRNA binding 16/3070 80/18639 0.2 1.2142671009772 0.236113176544013 0.528941783910352 GO:0140359 ABC-type transporter activity 10/3070 47/18639 0.212765957446809 1.29177351167787 0.237171288385054 0.52950805471366 GO:0140938 histone H3 methyltransferase activity 10/3070 47/18639 0.212765957446809 1.29177351167787 0.237171288385054 0.52950805471366 GO:0061980 regulatory RNA binding 12/3070 58/18639 0.206896551724138 1.25613838032124 0.238545414392163 0.531673254111346 GO:0005452 solute:inorganic anion antiporter activity 7/3070 31/18639 0.225806451612903 1.37094672690974 0.240356765120053 0.533900584683901 GO:0047499 calcium-independent phospholipase A2 activity 7/3070 31/18639 0.225806451612903 1.37094672690974 0.240356765120053 0.533900584683901 GO:0005506 iron ion binding 29/3070 154/18639 0.188311688311688 1.14330343923178 0.243017294211973 0.538900070638692 GO:0016829 lyase activity 37/3070 200/18639 0.185 1.12319706840391 0.244093240532647 0.540374766499041 GO:0019894 kinesin binding 9/3070 42/18639 0.214285714285714 1.30100046533271 0.246605861412827 0.544105214358838 GO:0035198 miRNA binding 9/3070 42/18639 0.214285714285714 1.30100046533271 0.246605861412827 0.544105214358838 GO:0019865 immunoglobulin binding 6/3070 26/18639 0.230769230769231 1.40107742420446 0.248620101766555 0.545802059804708 GO:0030507 spectrin binding 6/3070 26/18639 0.230769230769231 1.40107742420446 0.248620101766555 0.545802059804708 GO:0070412 R-SMAD binding 6/3070 26/18639 0.230769230769231 1.40107742420446 0.248620101766555 0.545802059804708 GO:0008373 sialyltransferase activity 5/3070 21/18639 0.238095238095238 1.4455560725919 0.256596211171144 0.560572065339486 GO:0019200 carbohydrate kinase activity 5/3070 21/18639 0.238095238095238 1.4455560725919 0.256596211171144 0.560572065339486 GO:0070001 aspartic-type peptidase activity 8/3070 37/18639 0.216216216216216 1.31272119024562 0.256626907478609 0.560572065339486 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 31/3070 167/18639 0.18562874251497 1.12701437515848 0.260688031183766 0.560575965389795 GO:0004708 MAP kinase kinase activity 4/3070 16/18639 0.25 1.5178338762215 0.263466087078112 0.560575965389795 GO:0005149 interleukin-1 receptor binding 4/3070 16/18639 0.25 1.5178338762215 0.263466087078112 0.560575965389795 GO:0005159 insulin-like growth factor receptor binding 4/3070 16/18639 0.25 1.5178338762215 0.263466087078112 0.560575965389795 GO:0015385 sodium:proton antiporter activity 4/3070 16/18639 0.25 1.5178338762215 0.263466087078112 0.560575965389795 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4/3070 16/18639 0.25 1.5178338762215 0.263466087078112 0.560575965389795 GO:0019842 vitamin binding 28/3070 150/18639 0.186666666666667 1.13331596091205 0.263563804527102 0.560575965389795 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0004143 ATP-dependent diacylglycerol kinase activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0005114 type II transforming growth factor beta receptor binding 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0010854 adenylate cyclase regulator activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0015173 aromatic amino acid transmembrane transporter activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0015205 nucleobase transmembrane transporter activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0019203 carbohydrate phosphatase activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0032050 clathrin heavy chain binding 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0034056 estrogen response element binding 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0048185 activin binding 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0097493 structural molecule activity conferring elasticity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0140537 transcription regulator activator activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0180030 inositol phosphate kinase activity 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:1900750 oligopeptide binding 3/3070 11/18639 0.272727272727273 1.65581877405982 0.266947614994081 0.560575965389795 GO:0140142 nucleocytoplasmic carrier activity 7/3070 32/18639 0.21875 1.32810464169381 0.267286030645933 0.560575965389795 GO:0140767 enzyme-substrate adaptor activity 26/3070 139/18639 0.18705035971223 1.13564549012256 0.269560532619719 0.56403265599758 GO:0008200 ion channel inhibitor activity 9/3070 43/18639 0.209302325581395 1.27074464055753 0.269792046100744 0.56403265599758 GO:0140104 molecular carrier activity 45/3070 249/18639 0.180722891566265 1.09722930811193 0.270344089914501 0.56428964799614 GO:0004364 glutathione transferase activity 6/3070 27/18639 0.222222222222222 1.34918566775244 0.278624668667112 0.577904478386833 GO:0004683 calcium/calmodulin-dependent protein kinase activity 6/3070 27/18639 0.222222222222222 1.34918566775244 0.278624668667112 0.577904478386833 GO:0005044 scavenger receptor activity 6/3070 27/18639 0.222222222222222 1.34918566775244 0.278624668667112 0.577904478386833 GO:0016405 CoA-ligase activity 6/3070 27/18639 0.222222222222222 1.34918566775244 0.278624668667112 0.577904478386833 GO:0016763 pentosyltransferase activity 10/3070 49/18639 0.204081632653061 1.23904806222163 0.280702959031388 0.581298253742165 GO:0004407 histone deacetylase activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0008093 cytoskeletal anchor activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0033558 protein lysine deacetylase activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0033691 sialic acid binding 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0034062 5'-3' RNA polymerase activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0097747 RNA polymerase activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0140035 ubiquitin-like protein reader activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0140517 protein-RNA adaptor activity 5/3070 22/18639 0.227272727272727 1.37984897838318 0.290642120619095 0.594392517284774 GO:0005518 collagen binding 14/3070 72/18639 0.194444444444444 1.18053745928339 0.291921957371882 0.596082878795069 GO:0005200 structural constituent of cytoskeleton 21/3070 112/18639 0.1875 1.13837540716612 0.292972789093297 0.597301112647575 GO:0001046 core promoter sequence-specific DNA binding 9/3070 44/18639 0.204545454545455 1.24186408054486 0.293589002900135 0.597630865036652 GO:0019239 deaminase activity 7/3070 33/18639 0.212121212121212 1.28785904649097 0.294973774519613 0.597674134812467 GO:0019956 chemokine binding 7/3070 33/18639 0.212121212121212 1.28785904649097 0.294973774519613 0.597674134812467 GO:0140416 transcription regulator inhibitor activity 7/3070 33/18639 0.212121212121212 1.28785904649097 0.294973774519613 0.597674134812467 GO:0141108 transporter regulator activity 31/3070 170/18639 0.182352941176471 1.10712588618509 0.296083084347185 0.598998855256228 GO:0015026 coreceptor activity 12/3070 61/18639 0.19672131147541 1.19436108292839 0.297820602718257 0.601588467856388 GO:0004175 endopeptidase activity 71/3070 405/18639 0.175308641975309 1.06435758233804 0.300024399942689 0.605110561234105 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/3070 17/18639 0.235294117647059 1.42854953056141 0.303193549166946 0.60777497460812 GO:0017110 nucleoside diphosphate phosphatase activity 4/3070 17/18639 0.235294117647059 1.42854953056141 0.303193549166946 0.60777497460812 GO:0032183 SUMO binding 4/3070 17/18639 0.235294117647059 1.42854953056141 0.303193549166946 0.60777497460812 GO:0051117 ATPase binding 16/3070 84/18639 0.19047619047619 1.15644485807352 0.303194207865344 0.60777497460812 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 8/3070 39/18639 0.205128205128205 1.24540215484841 0.307679241514902 0.613031841812851 GO:0046625 sphingolipid binding 6/3070 28/18639 0.214285714285714 1.30100046533271 0.309386340429675 0.613031841812851 GO:0046875 ephrin receptor binding 6/3070 28/18639 0.214285714285714 1.30100046533271 0.309386340429675 0.613031841812851 GO:0046966 nuclear thyroid hormone receptor binding 6/3070 28/18639 0.214285714285714 1.30100046533271 0.309386340429675 0.613031841812851 GO:0050698 proteoglycan sulfotransferase activity 6/3070 28/18639 0.214285714285714 1.30100046533271 0.309386340429675 0.613031841812851 GO:0097718 disordered domain specific binding 6/3070 28/18639 0.214285714285714 1.30100046533271 0.309386340429675 0.613031841812851 GO:0004859 phospholipase inhibitor activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0004875 complement receptor activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0005078 MAP-kinase scaffold activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0008179 adenylate cyclase binding 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0016273 arginine N-methyltransferase activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0016274 protein-arginine N-methyltransferase activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0016801 hydrolase activity, acting on ether bonds 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0016803 ether hydrolase activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0016840 carbon-nitrogen lyase activity 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0035197 siRNA binding 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0043047 single-stranded telomeric DNA binding 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0070410 co-SMAD binding 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0097677 STAT family protein binding 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 3/3070 12/18639 0.25 1.5178338762215 0.31560650715384 0.613031841812851 GO:0140303 intramembrane lipid transporter activity 9/3070 45/18639 0.2 1.2142671009772 0.317886342066214 0.616549468756742 GO:0015035 protein-disulfide reductase activity 7/3070 34/18639 0.205882352941176 1.24998083924123 0.323243368756327 0.625095632227308 GO:0016831 carboxy-lyase activity 7/3070 34/18639 0.205882352941176 1.24998083924123 0.323243368756327 0.625095632227308 GO:0031491 nucleosome binding 14/3070 74/18639 0.189189189189189 1.14863104146492 0.32979854124595 0.636835656003559 GO:0035250 UDP-galactosyltransferase activity 6/3070 29/18639 0.206896551724138 1.25613838032124 0.340669961628433 0.653260788678578 GO:0043236 laminin binding 6/3070 29/18639 0.206896551724138 1.25613838032124 0.340669961628433 0.653260788678578 GO:0004540 RNA nuclease activity 22/3070 121/18639 0.181818181818182 1.10387918270654 0.341279915207553 0.653260788678578 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 9/3070 46/18639 0.195652173913043 1.18786999008639 0.342572415773515 0.653260788678578 GO:0030276 clathrin binding 9/3070 46/18639 0.195652173913043 1.18786999008639 0.342572415773515 0.653260788678578 GO:0000900 mRNA regulatory element binding translation repressor activity 4/3070 18/18639 0.222222222222222 1.34918566775244 0.343491533134896 0.653260788678578 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/3070 18/18639 0.222222222222222 1.34918566775244 0.343491533134896 0.653260788678578 GO:0008525 phosphatidylcholine transporter activity 4/3070 18/18639 0.222222222222222 1.34918566775244 0.343491533134896 0.653260788678578 GO:1901611 phosphatidylglycerol binding 4/3070 18/18639 0.222222222222222 1.34918566775244 0.343491533134896 0.653260788678578 GO:0004519 endonuclease activity 23/3070 127/18639 0.181102362204724 1.09953320167227 0.34376917548713 0.653260788678578 GO:0042826 histone deacetylase binding 23/3070 127/18639 0.181102362204724 1.09953320167227 0.34376917548713 0.653260788678578 GO:0016887 ATP hydrolysis activity 72/3070 417/18639 0.172661870503597 1.04828814472852 0.348918030362485 0.662088326012508 GO:0008194 UDP-glycosyltransferase activity 26/3070 145/18639 0.179310344827586 1.08865326294507 0.350199949197524 0.663563304315193 GO:0004623 phospholipase A2 activity 7/3070 35/18639 0.2 1.2142671009772 0.351919310598609 0.665861717175785 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/3070 24/18639 0.208333333333333 1.26486156351792 0.360554086220058 0.673929088067229 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 5/3070 24/18639 0.208333333333333 1.26486156351792 0.360554086220058 0.673929088067229 GO:0050699 WW domain binding 5/3070 24/18639 0.208333333333333 1.26486156351792 0.360554086220058 0.673929088067229 GO:0004536 DNA nuclease activity 12/3070 64/18639 0.1875 1.13837540716612 0.360580837778703 0.673929088067229 GO:0042169 SH2 domain binding 8/3070 41/18639 0.195121951219512 1.18465083022166 0.360603701338492 0.673929088067229 GO:0002161 aminoacyl-tRNA editing activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0005172 vascular endothelial growth factor receptor binding 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0015651 quaternary ammonium group transmembrane transporter activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0019855 calcium channel inhibitor activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0030955 potassium ion binding 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0031432 titin binding 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0032396 inhibitory MHC class I receptor activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0140333 glycerophospholipid flippase activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0140852 histone ubiquitin ligase activity 3/3070 13/18639 0.230769230769231 1.40107742420446 0.364382951799087 0.673929088067229 GO:0016782 transferase activity, transferring sulphur-containing groups 13/3070 70/18639 0.185714285714286 1.12753373662168 0.364919461417789 0.673973443489316 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 6/3070 30/18639 0.2 1.2142671009772 0.372247339560371 0.685803431538108 GO:0005246 calcium channel regulator activity 10/3070 53/18639 0.188679245283019 1.14553500092189 0.37321009322978 0.685803431538108 GO:0005544 calcium-dependent phospholipid binding 10/3070 53/18639 0.188679245283019 1.14553500092189 0.37321009322978 0.685803431538108 GO:0140597 protein carrier chaperone 33/3070 188/18639 0.175531914893617 1.06571314713424 0.373410841810863 0.685803431538108 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 11/3070 59/18639 0.186440677966102 1.13194390769061 0.377946449928423 0.69123724847827 GO:0070063 RNA polymerase binding 11/3070 59/18639 0.186440677966102 1.13194390769061 0.377946449928423 0.69123724847827 GO:0070888 E-box binding 11/3070 59/18639 0.186440677966102 1.13194390769061 0.377946449928423 0.69123724847827 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0008381 mechanosensitive monoatomic ion channel activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0008574 plus-end-directed microtubule motor activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0031420 alkali metal ion binding 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0034987 immunoglobulin receptor binding 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0043395 heparan sulfate proteoglycan binding 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0046527 glucosyltransferase activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0046624 sphingolipid transporter activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0070003 threonine-type peptidase activity 4/3070 19/18639 0.210526315789474 1.27817589576547 0.383886902274348 0.692470886818611 GO:0004520 DNA endonuclease activity 8/3070 42/18639 0.19047619047619 1.15644485807352 0.387426722497472 0.69694410408232 GO:0016859 cis-trans isomerase activity 8/3070 42/18639 0.19047619047619 1.15644485807352 0.387426722497472 0.69694410408232 GO:0008135 translation factor activity, RNA binding 15/3070 83/18639 0.180722891566265 1.09722930811193 0.391024663199818 0.702455508343936 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 9/3070 48/18639 0.1875 1.13837540716612 0.392666896160668 0.704443340315524 GO:0008276 protein methyltransferase activity 17/3070 95/18639 0.178947368421053 1.08644951140065 0.395390968008962 0.705235700757202 GO:0005537 D-mannose binding 5/3070 25/18639 0.2 1.2142671009772 0.39579007388503 0.705235700757202 GO:0008483 transaminase activity 5/3070 25/18639 0.2 1.2142671009772 0.39579007388503 0.705235700757202 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 5/3070 25/18639 0.2 1.2142671009772 0.39579007388503 0.705235700757202 GO:0017056 structural constituent of nuclear pore 5/3070 25/18639 0.2 1.2142671009772 0.39579007388503 0.705235700757202 GO:0001098 basal transcription machinery binding 11/3070 60/18639 0.183333333333333 1.11307817589577 0.400476087861442 0.711656831807833 GO:0001099 basal RNA polymerase II transcription machinery binding 11/3070 60/18639 0.183333333333333 1.11307817589577 0.400476087861442 0.711656831807833 GO:0070273 phosphatidylinositol-4-phosphate binding 6/3070 31/18639 0.193548387096774 1.17509719449406 0.403901077426047 0.716034106798726 GO:0005262 calcium channel activity 23/3070 131/18639 0.175572519083969 1.06595966879678 0.404028370528254 0.716034106798726 GO:0004866 endopeptidase inhibitor activity 28/3070 161/18639 0.173913043478261 1.05588443563235 0.408320486370558 0.719475742282156 GO:0016874 ligase activity 29/3070 167/18639 0.173652694610778 1.05430377030954 0.408982882385684 0.719475742282156 GO:0019213 deacetylase activity 7/3070 37/18639 0.189189189189189 1.14863104146492 0.409810879146044 0.719475742282156 GO:0180051 translation factor activity 15/3070 84/18639 0.178571428571429 1.08416705444393 0.410118240446444 0.719475742282156 GO:0004518 nuclease activity 36/3070 209/18639 0.172248803827751 1.04578027835357 0.412403453774716 0.719475742282156 GO:0015386 potassium:proton antiporter activity 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0019763 immunoglobulin receptor activity 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0019992 diacylglycerol binding 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0032036 myosin heavy chain binding 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0046030 inositol trisphosphate phosphatase activity 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0098847 sequence-specific single stranded DNA binding 3/3070 14/18639 0.214285714285714 1.30100046533271 0.412535900897905 0.719475742282156 GO:0004896 cytokine receptor activity 17/3070 96/18639 0.177083333333333 1.07513232899023 0.413267767362193 0.719797502094415 GO:0016247 channel regulator activity 29/3070 168/18639 0.172619047619048 1.04802815262913 0.422539773589634 0.733558329587031 GO:0016836 hydro-lyase activity 11/3070 61/18639 0.180327868852459 1.09483099268436 0.423060294592942 0.733558329587031 GO:0000339 RNA cap binding 4/3070 20/18639 0.2 1.2142671009772 0.423957665768931 0.733558329587031 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/3070 20/18639 0.2 1.2142671009772 0.423957665768931 0.733558329587031 GO:0015095 magnesium ion transmembrane transporter activity 4/3070 20/18639 0.2 1.2142671009772 0.423957665768931 0.733558329587031 GO:0004521 RNA endonuclease activity 13/3070 73/18639 0.178082191780822 1.08119673374682 0.426659179931957 0.7372625776748 GO:0008378 galactosyltransferase activity 6/3070 32/18639 0.1875 1.13837540716612 0.435427626682997 0.748480168742667 GO:0031369 translation initiation factor binding 6/3070 32/18639 0.1875 1.13837540716612 0.435427626682997 0.748480168742667 GO:0042910 xenobiotic transmembrane transporter activity 6/3070 32/18639 0.1875 1.13837540716612 0.435427626682997 0.748480168742667 GO:0047498 calcium-dependent phospholipase A2 activity 6/3070 32/18639 0.1875 1.13837540716612 0.435427626682997 0.748480168742667 GO:1990841 promoter-specific chromatin binding 12/3070 68/18639 0.176470588235294 1.07141214792106 0.446552829678435 0.766362265074454 GO:0001217 DNA-binding transcription repressor activity 47/3070 278/18639 0.169064748201439 1.02644880838001 0.446996089210727 0.766362265074454 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 21/3070 122/18639 0.172131147540984 1.04506594756234 0.449823366776579 0.769372582239419 GO:0046906 tetrapyrrole binding 26/3070 152/18639 0.171052631578947 1.03851791530945 0.449922065203128 0.769372582239419 GO:0004129 cytochrome-c oxidase activity 3/3070 15/18639 0.2 1.2142671009772 0.459463373600866 0.781622686009235 GO:0010181 FMN binding 3/3070 15/18639 0.2 1.2142671009772 0.459463373600866 0.781622686009235 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/3070 15/18639 0.2 1.2142671009772 0.459463373600866 0.781622686009235 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 3/3070 15/18639 0.2 1.2142671009772 0.459463373600866 0.781622686009235 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 4/3070 21/18639 0.19047619047619 1.15644485807352 0.463336831556645 0.783146444083533 GO:0001846 opsonin binding 4/3070 21/18639 0.19047619047619 1.15644485807352 0.463336831556645 0.783146444083533 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/3070 21/18639 0.19047619047619 1.15644485807352 0.463336831556645 0.783146444083533 GO:0035613 RNA stem-loop binding 4/3070 21/18639 0.19047619047619 1.15644485807352 0.463336831556645 0.783146444083533 GO:1904047 S-adenosyl-L-methionine binding 4/3070 21/18639 0.19047619047619 1.15644485807352 0.463336831556645 0.783146444083533 GO:0003774 cytoskeletal motor activity 26/3070 153/18639 0.169934640522876 1.03173021651657 0.464308362120347 0.783781124760278 GO:0030296 protein tyrosine kinase activator activity 6/3070 33/18639 0.181818181818182 1.10387918270654 0.466639593830416 0.785132974697947 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 7/3070 39/18639 0.179487179487179 1.08972688549236 0.467367177657706 0.785132974697947 GO:0016776 phosphotransferase activity, phosphate group as acceptor 7/3070 39/18639 0.179487179487179 1.08972688549236 0.467367177657706 0.785132974697947 GO:0008081 phosphoric diester hydrolase activity 15/3070 87/18639 0.172413793103448 1.04678198360103 0.467497429040678 0.785132974697947 GO:0004601 peroxidase activity 10/3070 57/18639 0.175438596491228 1.06514657980456 0.468107960775972 0.785155571964801 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 45/3070 268/18639 0.167910447761194 1.01944066313384 0.469164000044208 0.785924407717368 GO:0019838 growth factor binding 23/3070 136/18639 0.169117647058824 1.02676997509101 0.480543210814602 0.803007772011229 GO:0008013 beta-catenin binding 18/3070 106/18639 0.169811320754717 1.0309815008297 0.484060391252617 0.803007772011229 GO:0016758 hexosyltransferase activity 33/3070 197/18639 0.16751269035533 1.01702574447329 0.487502339328696 0.803007772011229 GO:0017022 myosin binding 13/3070 76/18639 0.171052631578947 1.03851791530945 0.488348653603635 0.803007772011229 GO:0008017 microtubule binding 46/3070 276/18639 0.166666666666667 1.01188925081433 0.490267055731611 0.803007772011229 GO:0008408 3'-5' exonuclease activity 10/3070 58/18639 0.172413793103448 1.04678198360103 0.491558020588549 0.803007772011229 GO:0004386 helicase activity 26/3070 155/18639 0.167741935483871 1.01841756856152 0.492997334242025 0.803007772011229 GO:0004532 RNA exonuclease activity 7/3070 40/18639 0.175 1.06248371335505 0.495662225306705 0.803007772011229 GO:0008175 tRNA methyltransferase activity 6/3070 34/18639 0.176470588235294 1.07141214792106 0.497367356346292 0.803007772011229 GO:0008376 acetylgalactosaminyltransferase activity 6/3070 34/18639 0.176470588235294 1.07141214792106 0.497367356346292 0.803007772011229 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 6/3070 34/18639 0.176470588235294 1.07141214792106 0.497367356346292 0.803007772011229 GO:0008168 methyltransferase activity 34/3070 204/18639 0.166666666666667 1.01188925081433 0.499295867323632 0.803007772011229 GO:0016866 intramolecular transferase activity 5/3070 28/18639 0.178571428571429 1.08416705444393 0.49934375450148 0.803007772011229 GO:0019789 SUMO transferase activity 5/3070 28/18639 0.178571428571429 1.08416705444393 0.49934375450148 0.803007772011229 GO:0051959 dynein light intermediate chain binding 5/3070 28/18639 0.178571428571429 1.08416705444393 0.49934375450148 0.803007772011229 GO:0017171 serine hydrolase activity 33/3070 198/18639 0.166666666666667 1.01188925081433 0.500181571241925 0.803007772011229 GO:0008970 phospholipase A1 activity 4/3070 22/18639 0.181818181818182 1.10387918270654 0.501713433987212 0.803007772011229 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/3070 16/18639 0.1875 1.13837540716612 0.504693516644578 0.803007772011229 GO:0022841 potassium ion leak channel activity 3/3070 16/18639 0.1875 1.13837540716612 0.504693516644578 0.803007772011229 GO:0030275 LRR domain binding 3/3070 16/18639 0.1875 1.13837540716612 0.504693516644578 0.803007772011229 GO:0043023 ribosomal large subunit binding 3/3070 16/18639 0.1875 1.13837540716612 0.504693516644578 0.803007772011229 GO:0000182 rDNA binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0005337 nucleoside transmembrane transporter activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0005528 FK506 binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0008190 eukaryotic initiation factor 4E binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0015187 glycine transmembrane transporter activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0015643 toxic substance binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0031996 thioesterase binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0035256 G protein-coupled glutamate receptor binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0043121 neurotrophin binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0047429 nucleoside triphosphate diphosphatase activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0051864 histone H3K36 demethylase activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0051880 G-quadruplex DNA binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0098505 G-rich strand telomeric DNA binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0099122 RNA polymerase II C-terminal domain binding 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0140999 histone H3K4 trimethyltransferase activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0141109 transporter activator activity 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/3070 10/18639 0.2 1.2142671009772 0.508673364323463 0.803007772011229 GO:0004864 protein phosphatase inhibitor activity 9/3070 53/18639 0.169811320754717 1.0309815008297 0.517258391520962 0.815581276798639 GO:0030414 peptidase inhibitor activity 28/3070 169/18639 0.165680473372781 1.00590174045448 0.518745478182158 0.816946471628189 GO:0008236 serine-type peptidase activity 32/3070 194/18639 0.164948453608247 1.00145740286779 0.526680368965091 0.827696865081683 GO:0000175 3'-5'-RNA exonuclease activity 6/3070 35/18639 0.171428571428571 1.04080037226617 0.527460055466502 0.827696865081683 GO:0140566 histone reader activity 6/3070 35/18639 0.171428571428571 1.04080037226617 0.527460055466502 0.827696865081683 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 10/3070 60/18639 0.166666666666667 1.01188925081433 0.537597648928288 0.842524729207423 GO:0003887 DNA-directed DNA polymerase activity 4/3070 23/18639 0.173913043478261 1.05588443563235 0.538831404763074 0.842524729207423 GO:0016849 phosphorus-oxygen lyase activity 4/3070 23/18639 0.173913043478261 1.05588443563235 0.538831404763074 0.842524729207423 GO:0140463 chromatin-protein adaptor activity 9/3070 54/18639 0.166666666666667 1.01188925081433 0.541323277251841 0.845415807109467 GO:1901681 sulfur compound binding 45/3070 275/18639 0.163636363636364 0.99349126443589 0.544818886414558 0.849230439022851 GO:0016879 ligase activity, forming carbon-nitrogen bonds 8/3070 48/18639 0.166666666666667 1.01188925081433 0.545619982350528 0.849230439022851 GO:0004550 nucleoside diphosphate kinase activity 3/3070 17/18639 0.176470588235294 1.07141214792106 0.547872081104071 0.849230439022851 GO:0016018 cyclosporin A binding 3/3070 17/18639 0.176470588235294 1.07141214792106 0.547872081104071 0.849230439022851 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/3070 17/18639 0.176470588235294 1.07141214792106 0.547872081104071 0.849230439022851 GO:0070492 oligosaccharide binding 3/3070 17/18639 0.176470588235294 1.07141214792106 0.547872081104071 0.849230439022851 GO:0043175 RNA polymerase core enzyme binding 7/3070 42/18639 0.166666666666667 1.01188925081433 0.550676725907757 0.849230439022851 GO:0042054 histone methyltransferase activity 11/3070 67/18639 0.164179104477612 0.996786426175312 0.555784623171264 0.849230439022851 GO:0044390 ubiquitin-like protein conjugating enzyme binding 6/3070 36/18639 0.166666666666667 1.01188925081433 0.556786041009902 0.849230439022851 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 6/3070 36/18639 0.166666666666667 1.01188925081433 0.556786041009902 0.849230439022851 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 6/3070 36/18639 0.166666666666667 1.01188925081433 0.556786041009902 0.849230439022851 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 6/3070 36/18639 0.166666666666667 1.01188925081433 0.556786041009902 0.849230439022851 GO:0008170 N-methyltransferase activity 16/3070 98/18639 0.163265306122449 0.991238449777305 0.557765656539678 0.849230439022851 GO:0016741 transferase activity, transferring one-carbon groups 35/3070 215/18639 0.162790697674419 0.988356942655859 0.559179799213755 0.849230439022851 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0001851 complement component C3b binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0004016 adenylate cyclase activity 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0005536 D-glucose binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0008271 secondary active sulfate transmembrane transporter activity 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0019215 intermediate filament binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0043522 leucine zipper domain binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0050998 nitric-oxide synthase binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0070697 activin receptor binding 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/3070 11/18639 0.181818181818182 1.10387918270654 0.56239019750777 0.849230439022851 GO:0099106 ion channel regulator activity 26/3070 160/18639 0.1625 0.986592019543974 0.563410329348062 0.849230439022851 GO:0031624 ubiquitin conjugating enzyme binding 5/3070 30/18639 0.166666666666667 1.01188925081433 0.564431485707964 0.849230439022851 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/3070 30/18639 0.166666666666667 1.01188925081433 0.564431485707964 0.849230439022851 GO:0070566 adenylyltransferase activity 5/3070 30/18639 0.166666666666667 1.01188925081433 0.564431485707964 0.849230439022851 GO:0048306 calcium-dependent protein binding 13/3070 80/18639 0.1625 0.986592019543974 0.568100649856905 0.853774119499235 GO:0020037 heme binding 23/3070 142/18639 0.161971830985915 0.983385328256182 0.570420702384376 0.856282218761934 GO:0003678 DNA helicase activity 12/3070 74/18639 0.162162162162162 0.984540892684215 0.57224669910581 0.856519537460608 GO:0003684 damaged DNA binding 12/3070 74/18639 0.162162162162162 0.984540892684215 0.57224669910581 0.856519537460608 GO:0042393 histone binding 40/3070 247/18639 0.161943319838057 0.983212227511902 0.573811025873314 0.856519537460608 GO:0004806 triacylglycerol lipase activity 4/3070 24/18639 0.166666666666667 1.01188925081433 0.574486868471678 0.856519537460608 GO:0070300 phosphatidic acid binding 4/3070 24/18639 0.166666666666667 1.01188925081433 0.574486868471678 0.856519537460608 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/3070 24/18639 0.166666666666667 1.01188925081433 0.574486868471678 0.856519537460608 GO:0019212 phosphatase inhibitor activity 9/3070 56/18639 0.160714285714286 0.975750348999535 0.58798595357153 0.873819267232219 GO:0003746 translation elongation factor activity 3/3070 18/18639 0.166666666666667 1.01188925081433 0.588748190697906 0.873819267232219 GO:0017075 syntaxin-1 binding 3/3070 18/18639 0.166666666666667 1.01188925081433 0.588748190697906 0.873819267232219 GO:0070628 proteasome binding 3/3070 18/18639 0.166666666666667 1.01188925081433 0.588748190697906 0.873819267232219 GO:0016279 protein-lysine N-methyltransferase activity 11/3070 69/18639 0.159420289855072 0.967894065996318 0.597507799776616 0.876724054489755 GO:0015631 tubulin binding 62/3070 385/18639 0.161038961038961 0.977721561825796 0.599326669701375 0.876724054489755 GO:0043014 alpha-tubulin binding 7/3070 44/18639 0.159090909090909 0.965894284868226 0.602930575138726 0.876724054489755 GO:0000030 mannosyltransferase activity 4/3070 25/18639 0.16 0.971413680781759 0.608524353154849 0.876724054489755 GO:0001848 complement binding 4/3070 25/18639 0.16 0.971413680781759 0.608524353154849 0.876724054489755 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 4/3070 25/18639 0.16 0.971413680781759 0.608524353154849 0.876724054489755 GO:0140034 methylation-dependent protein binding 12/3070 76/18639 0.157894736842105 0.958631921824104 0.611583796395027 0.876724054489755 GO:0000340 RNA 7-methylguanosine cap binding 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0000995 RNA polymerase III general transcription initiation factor activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0004000 adenosine deaminase activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0005025 transforming growth factor beta receptor activity, type I 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0005026 transforming growth factor beta receptor activity, type II 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0005049 nuclear export signal receptor activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0005527 macrolide binding 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0008603 cAMP-dependent protein kinase regulator activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0010853 cyclase activator activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0015269 calcium-activated potassium channel activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0016208 AMP binding 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0016361 activin receptor activity, type I 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0016362 activin receptor activity, type II 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0017002 activin receptor activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0017166 vinculin binding 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0031543 peptidyl-proline dioxygenase activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0035251 UDP-glucosyltransferase activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0070679 inositol 1,4,5 trisphosphate binding 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0140829 bicarbonate:monoatomic anion antiporter activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0140900 chloride:bicarbonate antiporter activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/3070 12/18639 0.166666666666667 1.01188925081433 0.611746935578556 0.876724054489755 GO:0000146 microfilament motor activity 6/3070 38/18639 0.157894736842105 0.958631921824104 0.612706772681433 0.876724054489755 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/3070 38/18639 0.157894736842105 0.958631921824104 0.612706772681433 0.876724054489755 GO:0042162 telomeric DNA binding 6/3070 38/18639 0.157894736842105 0.958631921824104 0.612706772681433 0.876724054489755 GO:0016278 lysine N-methyltransferase activity 11/3070 70/18639 0.157142857142857 0.954067007910656 0.617673127865931 0.8828697425475 GO:0003743 translation initiation factor activity 8/3070 51/18639 0.156862745098039 0.952366353707607 0.618437443535247 0.883002430237622 GO:0015106 bicarbonate transmembrane transporter activity 5/3070 32/18639 0.15625 0.948646172638437 0.624909216474847 0.887913777260837 GO:0030515 snoRNA binding 5/3070 32/18639 0.15625 0.948646172638437 0.624909216474847 0.887913777260837 GO:0005520 insulin-like growth factor binding 3/3070 19/18639 0.157894736842105 0.958631921824104 0.627159682277323 0.887913777260837 GO:0022821 solute:potassium antiporter activity 3/3070 19/18639 0.157894736842105 0.958631921824104 0.627159682277323 0.887913777260837 GO:0022840 leak channel activity 3/3070 19/18639 0.157894736842105 0.958631921824104 0.627159682277323 0.887913777260837 GO:0022842 narrow pore channel activity 3/3070 19/18639 0.157894736842105 0.958631921824104 0.627159682277323 0.887913777260837 GO:0140036 ubiquitin-modified protein reader activity 3/3070 19/18639 0.157894736842105 0.958631921824104 0.627159682277323 0.887913777260837 GO:0046873 metal ion transmembrane transporter activity 72/3070 450/18639 0.16 0.971413680781759 0.627279010703664 0.887913777260837 GO:0017116 single-stranded DNA helicase activity 9/3070 58/18639 0.155172413793103 0.94210378524093 0.632302781500071 0.894062535131821 GO:0004529 DNA exonuclease activity 4/3070 26/18639 0.153846153846154 0.934051616136307 0.640832318558085 0.903209537946283 GO:0005227 calcium-activated cation channel activity 4/3070 26/18639 0.153846153846154 0.934051616136307 0.640832318558085 0.903209537946283 GO:0030247 polysaccharide binding 4/3070 26/18639 0.153846153846154 0.934051616136307 0.640832318558085 0.903209537946283 GO:0004527 exonuclease activity 13/3070 84/18639 0.154761904761905 0.939611447184737 0.642507397206892 0.904600885789147 GO:0004222 metalloendopeptidase activity 17/3070 110/18639 0.154545454545455 0.938297305300563 0.652801702121246 0.909999683924113 GO:0015459 potassium channel regulator activity 9/3070 59/18639 0.152542372881356 0.926135924474135 0.653463352194998 0.909999683924113 GO:0004465 lipoprotein lipase activity 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0004535 poly(A)-specific ribonuclease activity 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0005542 folic acid binding 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0019104 DNA N-glycosylase activity 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0031994 insulin-like growth factor I binding 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0061459 L-arginine transmembrane transporter activity 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0070123 transforming growth factor beta receptor activity, type III 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0070700 BMP receptor binding 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0071714 icosanoid transmembrane transporter activity 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0097157 pre-mRNA intronic binding 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0140666 annealing activity 2/3070 13/18639 0.153846153846154 0.934051616136307 0.656722205356641 0.909999683924113 GO:0010851 cyclase regulator activity 3/3070 20/18639 0.15 0.910700325732899 0.663018861661157 0.917222284066952 GO:0016251 RNA polymerase II general transcription initiation factor activity 8/3070 53/18639 0.150943396226415 0.916428000737508 0.663329575777697 0.917222284066952 GO:0061749 forked DNA-dependent helicase activity 7/3070 47/18639 0.148936170212766 0.90424145817451 0.6748619279073 0.931210320249842 GO:1990518 single-stranded 3'-5' DNA helicase activity 7/3070 47/18639 0.148936170212766 0.90424145817451 0.6748619279073 0.931210320249842 GO:0016209 antioxidant activity 13/3070 86/18639 0.151162790697674 0.917760018180441 0.677067541098507 0.933274440822366 GO:0050840 extracellular matrix binding 10/3070 67/18639 0.149253731343284 0.906169478341193 0.683723973912217 0.937737421715599 GO:0001530 lipopolysaccharide binding 6/3070 41/18639 0.146341463414634 0.888488122666243 0.688618716387271 0.937737421715599 GO:0017080 sodium channel regulator activity 6/3070 41/18639 0.146341463414634 0.888488122666243 0.688618716387271 0.937737421715599 GO:0035064 methylated histone binding 11/3070 74/18639 0.148648648648649 0.902495818293864 0.692891384065552 0.937737421715599 GO:0009975 cyclase activity 3/3070 21/18639 0.142857142857143 0.867333643555142 0.696299200011909 0.937737421715599 GO:0070182 DNA polymerase binding 3/3070 21/18639 0.142857142857143 0.867333643555142 0.696299200011909 0.937737421715599 GO:0009378 four-way junction helicase activity 7/3070 48/18639 0.145833333333333 0.885403094462541 0.696927625929188 0.937737421715599 GO:0036121 double-stranded DNA helicase activity 7/3070 48/18639 0.145833333333333 0.885403094462541 0.696927625929188 0.937737421715599 GO:0043138 3'-5' DNA helicase activity 7/3070 48/18639 0.145833333333333 0.885403094462541 0.696927625929188 0.937737421715599 GO:0005161 platelet-derived growth factor receptor binding 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0005313 L-glutamate transmembrane transporter activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0008174 mRNA methyltransferase activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0008559 ABC-type xenobiotic transporter activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0015926 glucosidase activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0031404 chloride ion binding 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0032454 histone H3K9 demethylase activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0043176 amine binding 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0070742 C2H2 zinc finger domain binding 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0098821 BMP receptor activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:1901474 azole transmembrane transporter activity 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:1901612 cardiolipin binding 2/3070 14/18639 0.142857142857143 0.867333643555142 0.697419922766431 0.937737421715599 GO:0140101 catalytic activity, acting on a tRNA 21/3070 139/18639 0.151079136690647 0.917252126637452 0.702451576129421 0.943538123197332 GO:0005154 epidermal growth factor receptor binding 5/3070 35/18639 0.142857142857143 0.867333643555142 0.705463525303179 0.944688936633076 GO:0034061 DNA polymerase activity 5/3070 35/18639 0.142857142857143 0.867333643555142 0.705463525303179 0.944688936633076 GO:0043015 gamma-tubulin binding 5/3070 35/18639 0.142857142857143 0.867333643555142 0.705463525303179 0.944688936633076 GO:0015293 symporter activity 22/3070 146/18639 0.150684931506849 0.914858774708848 0.710058708016301 0.949875077356496 GO:0042056 chemoattractant activity 6/3070 42/18639 0.142857142857143 0.867333643555142 0.711609048133857 0.950981603959371 GO:0061775 cohesin loader activity 23/3070 153/18639 0.150326797385621 0.912684422303123 0.717333788757944 0.956637897689836 GO:0003727 single-stranded RNA binding 13/3070 89/18639 0.146067415730337 0.886824287230538 0.725129082162165 0.956637897689836 GO:0003785 actin monomer binding 4/3070 29/18639 0.137931034482759 0.837425586880827 0.726820612024455 0.956637897689836 GO:0004181 metallocarboxypeptidase activity 4/3070 29/18639 0.137931034482759 0.837425586880827 0.726820612024455 0.956637897689836 GO:0004629 phospholipase C activity 4/3070 29/18639 0.137931034482759 0.837425586880827 0.726820612024455 0.956637897689836 GO:0005416 amino acid:monoatomic cation symporter activity 4/3070 29/18639 0.137931034482759 0.837425586880827 0.726820612024455 0.956637897689836 GO:0106222 lncRNA binding 4/3070 29/18639 0.137931034482759 0.837425586880827 0.726820612024455 0.956637897689836 GO:0015377 chloride:monoatomic cation symporter activity 3/3070 22/18639 0.136363636363636 0.827909387029908 0.727023268331598 0.956637897689836 GO:0070034 telomerase RNA binding 3/3070 22/18639 0.136363636363636 0.827909387029908 0.727023268331598 0.956637897689836 GO:0000993 RNA polymerase II complex binding 5/3070 36/18639 0.138888888888889 0.843241042345277 0.729443764705321 0.956637897689836 GO:0045505 dynein intermediate chain binding 5/3070 36/18639 0.138888888888889 0.843241042345277 0.729443764705321 0.956637897689836 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0005523 tropomyosin binding 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0008252 nucleotidase activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0015116 sulfate transmembrane transporter activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0016846 carbon-sulfur lyase activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0031386 protein tag activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0034483 heparan sulfate sulfotransferase activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0048531 beta-1,3-galactosyltransferase activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0051371 muscle alpha-actinin binding 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0141047 molecular tag activity 2/3070 15/18639 0.133333333333333 0.809511400651466 0.734028622638056 0.956637897689836 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 27/3070 181/18639 0.149171270718232 0.905668832220563 0.74360189559959 0.968154943280655 GO:0022839 monoatomic ion-gated channel activity 4/3070 30/18639 0.133333333333333 0.809511400651466 0.751803554534685 0.976555007812136 GO:0033612 receptor serine/threonine kinase binding 4/3070 30/18639 0.133333333333333 0.809511400651466 0.751803554534685 0.976555007812136 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/3070 23/18639 0.130434782608696 0.79191332672426 0.755252047866876 0.976555007812136 GO:0005212 structural constituent of eye lens 3/3070 23/18639 0.130434782608696 0.79191332672426 0.755252047866876 0.976555007812136 GO:0005283 amino acid:sodium symporter activity 3/3070 23/18639 0.130434782608696 0.79191332672426 0.755252047866876 0.976555007812136 GO:0017134 fibroblast growth factor binding 3/3070 23/18639 0.130434782608696 0.79191332672426 0.755252047866876 0.976555007812136 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/3070 23/18639 0.130434782608696 0.79191332672426 0.755252047866876 0.976555007812136 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0005024 transforming growth factor beta receptor activity 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0008296 3'-5'-DNA exonuclease activity 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0015562 efflux transmembrane transporter activity 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0019841 retinol binding 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/3070 16/18639 0.125 0.758916938110749 0.766790780637125 0.982136893053597 GO:0000510 H3-H4 histone complex chaperone activity 22/3070 151/18639 0.145695364238411 0.884565437797959 0.767784582554447 0.982136893053597 GO:0140584 chromatin extrusion motor activity 22/3070 151/18639 0.145695364238411 0.884565437797959 0.767784582554447 0.982136893053597 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 22/3070 151/18639 0.145695364238411 0.884565437797959 0.767784582554447 0.982136893053597 GO:0140849 ATP-dependent H2AZ histone chaperone activity 22/3070 151/18639 0.145695364238411 0.884565437797959 0.767784582554447 0.982136893053597 GO:0140658 ATP-dependent chromatin remodeler activity 23/3070 158/18639 0.145569620253165 0.883802003875809 0.773041972382504 0.985714465522249 GO:0016835 carbon-oxygen lyase activity 11/3070 79/18639 0.139240506329114 0.845375829794252 0.773122608929714 0.985714465522249 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/3070 31/18639 0.129032258064516 0.783398129662709 0.774988863640584 0.985714465522249 GO:0008327 methyl-CpG binding 4/3070 31/18639 0.129032258064516 0.783398129662709 0.774988863640584 0.985714465522249 GO:0015616 DNA translocase activity 22/3070 152/18639 0.144736842105263 0.878745928338762 0.778361333107872 0.985714465522249 GO:0140674 ATP-dependent histone chaperone activity 22/3070 152/18639 0.144736842105263 0.878745928338762 0.778361333107872 0.985714465522249 GO:0070851 growth factor receptor binding 20/3070 139/18639 0.143884892086331 0.873573453940431 0.779088926474969 0.985714465522249 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0015149 hexose transmembrane transporter activity 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0030215 semaphorin receptor binding 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0030552 cAMP binding 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0055056 D-glucose transmembrane transporter activity 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0070840 dynein complex binding 3/3070 24/18639 0.125 0.758916938110749 0.781075644923333 0.985714465522249 GO:0019783 ubiquitin-like protein peptidase activity 18/3070 127/18639 0.141732283464567 0.860504244786991 0.79157255936725 0.995921619273023 GO:0008146 sulfotransferase activity 7/3070 53/18639 0.132075471698113 0.80187450064532 0.792081385705534 0.995921619273023 GO:0003689 DNA clamp loader activity 23/3070 160/18639 0.14375 0.872754478827361 0.793149366479418 0.995921619273023 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/3070 60/18639 0.133333333333333 0.809511400651466 0.793475691157909 0.995921619273023 GO:0031489 myosin V binding 2/3070 17/18639 0.117647058823529 0.714274765280705 0.795979940574865 0.995921619273023 GO:0038191 neuropilin binding 2/3070 17/18639 0.117647058823529 0.714274765280705 0.795979940574865 0.995921619273023 GO:0045125 bioactive lipid receptor activity 2/3070 17/18639 0.117647058823529 0.714274765280705 0.795979940574865 0.995921619273023 GO:0045236 CXCR chemokine receptor binding 2/3070 17/18639 0.117647058823529 0.714274765280705 0.795979940574865 0.995921619273023 GO:1990226 histone methyltransferase binding 2/3070 17/18639 0.117647058823529 0.714274765280705 0.795979940574865 0.995921619273023 GO:0003697 single-stranded DNA binding 17/3070 121/18639 0.140495867768595 0.852997550273239 0.798323960818027 0.99607970527132 GO:0015271 outward rectifier potassium channel activity 3/3070 25/18639 0.12 0.728560260586319 0.804605366528127 0.99607970527132 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/3070 25/18639 0.12 0.728560260586319 0.804605366528127 0.99607970527132 GO:0140098 catalytic activity, acting on RNA 58/3070 387/18639 0.149870801033592 0.90991591546095 0.80533422007769 0.99607970527132 GO:0101005 deubiquitinase activity 16/3070 115/18639 0.139130434782609 0.844707548505877 0.805457754223243 0.99607970527132 GO:0140097 catalytic activity, acting on DNA 50/3070 336/18639 0.148809523809524 0.903472545369939 0.805996601026159 0.99607970527132 GO:0140223 general transcription initiation factor activity 9/3070 68/18639 0.132352941176471 0.803559110940793 0.809749608694621 0.99607970527132 GO:0015144 carbohydrate transmembrane transporter activity 5/3070 40/18639 0.125 0.758916938110749 0.811108437738705 0.99607970527132 GO:0015294 solute:monoatomic cation symporter activity 16/3070 116/18639 0.137931034482759 0.837425586880827 0.816203983922747 0.99607970527132 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/3070 18/18639 0.111111111111111 0.674592833876221 0.821883909309485 0.99607970527132 GO:0008409 5'-3' exonuclease activity 2/3070 18/18639 0.111111111111111 0.674592833876221 0.821883909309485 0.99607970527132 GO:0015280 ligand-gated sodium channel activity 2/3070 18/18639 0.111111111111111 0.674592833876221 0.821883909309485 0.99607970527132 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/3070 18/18639 0.111111111111111 0.674592833876221 0.821883909309485 0.99607970527132 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3070 18/18639 0.111111111111111 0.674592833876221 0.821883909309485 0.99607970527132 GO:0098641 cadherin binding involved in cell-cell adhesion 2/3070 18/18639 0.111111111111111 0.674592833876221 0.821883909309485 0.99607970527132 GO:0030165 PDZ domain binding 11/3070 83/18639 0.132530120481928 0.804634825948746 0.825755878037242 0.99607970527132 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/3070 26/18639 0.115384615384615 0.70053871210223 0.825967068437262 0.99607970527132 GO:0004435 phosphatidylinositol phospholipase C activity 3/3070 26/18639 0.115384615384615 0.70053871210223 0.825967068437262 0.99607970527132 GO:0005112 Notch binding 3/3070 26/18639 0.115384615384615 0.70053871210223 0.825967068437262 0.99607970527132 GO:0008157 protein phosphatase 1 binding 3/3070 26/18639 0.115384615384615 0.70053871210223 0.825967068437262 0.99607970527132 GO:0015145 monosaccharide transmembrane transporter activity 3/3070 26/18639 0.115384615384615 0.70053871210223 0.825967068437262 0.99607970527132 GO:0004812 aminoacyl-tRNA ligase activity 5/3070 41/18639 0.121951219512195 0.740406768888536 0.828120899037515 0.99607970527132 GO:0016875 ligase activity, forming carbon-oxygen bonds 5/3070 41/18639 0.121951219512195 0.740406768888536 0.828120899037515 0.99607970527132 GO:0140713 histone chaperone activity 23/3070 164/18639 0.140243902439024 0.851467784221816 0.829603450292901 0.99607970527132 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 4/3070 34/18639 0.117647058823529 0.714274765280705 0.834342283936677 0.99607970527132 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/3070 34/18639 0.117647058823529 0.714274765280705 0.834342283936677 0.99607970527132 GO:0051427 hormone receptor binding 4/3070 34/18639 0.117647058823529 0.714274765280705 0.834342283936677 0.99607970527132 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0003796 lysozyme activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0004955 prostaglandin receptor activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0008401 retinoic acid 4-hydroxylase activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0015203 polyamine transmembrane transporter activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0031434 mitogen-activated protein kinase kinase binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0032052 bile acid binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0043208 glycosphingolipid binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0050815 phosphoserine residue binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0070097 delta-catenin binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0070739 protein-glutamic acid ligase activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0070740 tubulin-glutamic acid ligase activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0071723 lipopeptide binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0097177 mitochondrial ribosome binding 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0140135 mechanosensitive monoatomic cation channel activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0140940 histone H2A methyltransferase activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:1990259 histone H2AQ104 methyltransferase activity 1/3070 10/18639 0.1 0.607133550488599 0.834737517269198 0.99607970527132 GO:0008301 DNA binding, bending 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0016918 retinal binding 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0030506 ankyrin binding 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0042800 histone H3K4 methyltransferase activity 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0042834 peptidoglycan binding 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0050145 nucleoside monophosphate kinase activity 2/3070 19/18639 0.105263157894737 0.639087947882736 0.844792641901504 0.999319417728685 GO:0015252 proton channel activity 3/3070 27/18639 0.111111111111111 0.674592833876221 0.845295661501396 0.999319417728685 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/3070 27/18639 0.111111111111111 0.674592833876221 0.845295661501396 0.999319417728685 GO:0019199 transmembrane receptor protein kinase activity 10/3070 78/18639 0.128205128205128 0.778376346780255 0.847897595383868 0.999319417728685 GO:0046982 protein heterodimerization activity 54/3070 369/18639 0.146341463414634 0.888488122666243 0.849204566827451 0.999319417728685 GO:0003823 antigen binding 24/3070 174/18639 0.137931034482759 0.837425586880827 0.85616080512224 0.999319417728685 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/3070 43/18639 0.116279069767442 0.705969244754185 0.85839985788961 0.999319417728685 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0002162 dystroglycan binding 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0003953 NAD+ nucleosidase activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0004954 prostanoid receptor activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0008046 axon guidance receptor activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0008503 benzodiazepine receptor activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0032404 mismatch repair complex binding 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0045294 alpha-catenin binding 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0050786 RAGE receptor binding 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0070990 snRNP binding 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:1990948 ubiquitin ligase inhibitor activity 1/3070 11/18639 0.0909090909090909 0.551939591353272 0.86197224924534 0.999319417728685 GO:0005242 inward rectifier potassium channel activity 3/3070 28/18639 0.107142857142857 0.650500232666356 0.862730650622205 0.999319417728685 GO:0051119 sugar transmembrane transporter activity 3/3070 28/18639 0.107142857142857 0.650500232666356 0.862730650622205 0.999319417728685 GO:0001972 retinoic acid binding 2/3070 20/18639 0.1 0.607133550488599 0.864989728594876 0.999319417728685 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 2/3070 20/18639 0.1 0.607133550488599 0.864989728594876 0.999319417728685 GO:0005326 neurotransmitter transmembrane transporter activity 2/3070 20/18639 0.1 0.607133550488599 0.864989728594876 0.999319417728685 GO:0055106 ubiquitin-protein transferase regulator activity 4/3070 36/18639 0.111111111111111 0.674592833876221 0.866162805739007 0.999319417728685 GO:0005021 vascular endothelial growth factor receptor activity 6/3070 51/18639 0.117647058823529 0.714274765280705 0.866330141605096 0.999319417728685 GO:0016597 amino acid binding 6/3070 51/18639 0.117647058823529 0.714274765280705 0.866330141605096 0.999319417728685 GO:0004843 cysteine-type deubiquitinase activity 14/3070 108/18639 0.12962962962963 0.787024972855592 0.869722732762 1 GO:0004252 serine-type endopeptidase activity 24/3070 176/18639 0.136363636363636 0.827909387029908 0.870306243609546 1 GO:0030547 signaling receptor inhibitor activity 5/3070 44/18639 0.113636363636364 0.68992448919159 0.871783437823227 1 GO:0008094 ATP-dependent activity, acting on DNA 29/3070 210/18639 0.138095238095238 0.838422522103304 0.874217034928591 1 GO:0030551 cyclic nucleotide binding 4/3070 37/18639 0.108108108108108 0.65636059512281 0.88000354332314 1 GO:0042805 actinin binding 4/3070 37/18639 0.108108108108108 0.65636059512281 0.88000354332314 1 GO:0008173 RNA methyltransferase activity 8/3070 67/18639 0.119402985074627 0.724935582672955 0.881886736650034 1 GO:0015125 bile acid transmembrane transporter activity 2/3070 21/18639 0.0952380952380952 0.578222429036761 0.882746626340452 1 GO:0015174 basic amino acid transmembrane transporter activity 2/3070 21/18639 0.0952380952380952 0.578222429036761 0.882746626340452 1 GO:0061891 calcium ion sensor activity 2/3070 21/18639 0.0952380952380952 0.578222429036761 0.882746626340452 1 GO:0008009 chemokine activity 5/3070 45/18639 0.111111111111111 0.674592833876221 0.884078769686952 1 GO:0003720 telomerase activity 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0004032 aldose reductase (NADPH) activity 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0004126 cytidine deaminase activity 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0005165 neurotrophin receptor binding 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0008504 monoamine transmembrane transporter activity 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0015132 prostaglandin transmembrane transporter activity 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0036009 protein-glutamine N-methyltransferase activity 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0042301 phosphate ion binding 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0045295 gamma-catenin binding 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0097371 MDM2/MDM4 family protein binding 1/3070 12/18639 0.0833333333333333 0.505944625407166 0.88472000503323 1 GO:0003777 microtubule motor activity 8/3070 68/18639 0.117647058823529 0.714274765280705 0.891505020377423 1 GO:0048019 receptor antagonist activity 3/3070 30/18639 0.1 0.607133550488599 0.892480247443607 1 GO:0005501 retinoid binding 4/3070 38/18639 0.105263157894737 0.639087947882736 0.89258299219164 1 GO:0019840 isoprenoid binding 4/3070 38/18639 0.105263157894737 0.639087947882736 0.89258299219164 1 GO:0140784 metal ion sensor activity 2/3070 22/18639 0.0909090909090909 0.551939591353272 0.898318962141337 1 GO:0003964 RNA-directed DNA polymerase activity 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0008253 5'-nucleotidase activity 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0008417 fucosyltransferase activity 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0009982 pseudouridine synthase activity 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0039706 co-receptor binding 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0045159 myosin II binding 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0071837 HMG box domain binding 1/3070 13/18639 0.0769230769230769 0.467025808068153 0.903719821672946 1 GO:0098632 cell-cell adhesion mediator activity 6/3070 55/18639 0.109090909090909 0.662327509623927 0.908706568469272 1 GO:0099186 structural constituent of postsynapse 2/3070 23/18639 0.0869565217391304 0.527942217816173 0.911944382548428 1 GO:0008195 phosphatidate phosphatase activity 1/3070 14/18639 0.0714285714285714 0.433666821777571 0.919589044665754 1 GO:0008392 arachidonate epoxygenase activity 1/3070 14/18639 0.0714285714285714 0.433666821777571 0.919589044665754 1 GO:0008494 translation activator activity 1/3070 14/18639 0.0714285714285714 0.433666821777571 0.919589044665754 1 GO:0042043 neurexin family protein binding 1/3070 14/18639 0.0714285714285714 0.433666821777571 0.919589044665754 1 GO:0061783 peptidoglycan muralytic activity 1/3070 14/18639 0.0714285714285714 0.433666821777571 0.919589044665754 1 GO:0035254 glutamate receptor binding 5/3070 49/18639 0.102040816326531 0.619524031110816 0.92364180040301 1 GO:0042379 chemokine receptor binding 8/3070 72/18639 0.111111111111111 0.674592833876221 0.923656836887909 1 GO:0019957 C-C chemokine binding 2/3070 24/18639 0.0833333333333333 0.505944625407166 0.923841540514346 1 GO:0008201 heparin binding 22/3070 172/18639 0.127906976744186 0.776566169229604 0.924637745863595 1 GO:0019843 rRNA binding 7/3070 65/18639 0.107692307692308 0.653836131295415 0.927479608653925 1 GO:0031492 nucleosomal DNA binding 4/3070 42/18639 0.0952380952380952 0.578222429036761 0.932023252095953 1 GO:0004953 icosanoid receptor activity 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0030553 cGMP binding 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0031005 filamin binding 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0033130 acetylcholine receptor binding 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0042809 nuclear vitamin D receptor binding 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0140161 monocarboxylate:sodium symporter activity 1/3070 15/18639 0.0666666666666667 0.404755700325733 0.932843360524876 1 GO:0005251 delayed rectifier potassium channel activity 2/3070 25/18639 0.08 0.48570684039088 0.93420990346967 1 GO:0005010 insulin-like growth factor receptor activity 5/3070 51/18639 0.0980392156862745 0.595228971067254 0.938515005665525 1 GO:0005030 neurotrophin receptor activity 5/3070 51/18639 0.0980392156862745 0.595228971067254 0.938515005665525 1 GO:0036002 pre-mRNA binding 6/3070 59/18639 0.101694915254237 0.617423949649423 0.938919476274219 1 GO:0005245 voltage-gated calcium channel activity 4/3070 43/18639 0.0930232558139535 0.564775395803348 0.939574369450449 1 GO:0005343 organic acid:sodium symporter activity 3/3070 35/18639 0.0857142857142857 0.520400186133085 0.943118344649285 1 GO:0001637 G protein-coupled chemoattractant receptor activity 2/3070 26/18639 0.0769230769230769 0.467025808068153 0.94323013972237 1 GO:0004950 chemokine receptor activity 2/3070 26/18639 0.0769230769230769 0.467025808068153 0.94323013972237 1 GO:0003688 DNA replication origin binding 1/3070 16/18639 0.0625 0.379458469055375 0.943913532517392 1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/3070 16/18639 0.0625 0.379458469055375 0.943913532517392 1 GO:0008391 arachidonate monooxygenase activity 1/3070 16/18639 0.0625 0.379458469055375 0.943913532517392 1 GO:0015378 sodium:chloride symporter activity 1/3070 16/18639 0.0625 0.379458469055375 0.943913532517392 1 GO:0097027 ubiquitin-protein transferase activator activity 1/3070 16/18639 0.0625 0.379458469055375 0.943913532517392 1 GO:0005003 ephrin receptor activity 5/3070 53/18639 0.0943396226415094 0.572767500460943 0.950729793153174 1 GO:0005005 transmembrane-ephrin receptor activity 5/3070 53/18639 0.0943396226415094 0.572767500460943 0.950729793153174 1 GO:0038064 collagen receptor activity 5/3070 53/18639 0.0943396226415094 0.572767500460943 0.950729793153174 1 GO:0008395 steroid hydroxylase activity 2/3070 27/18639 0.0740740740740741 0.449728555917481 0.951064897980048 1 GO:0035255 ionotropic glutamate receptor binding 2/3070 27/18639 0.0740740740740741 0.449728555917481 0.951064897980048 1 GO:0003724 RNA helicase activity 8/3070 77/18639 0.103896103896104 0.63078810440374 0.951990990151373 1 GO:0004549 tRNA-specific ribonuclease activity 1/3070 17/18639 0.0588235294117647 0.357137382640353 0.9531593820138 1 GO:0008569 minus-end-directed microtubule motor activity 1/3070 17/18639 0.0588235294117647 0.357137382640353 0.9531593820138 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/3070 17/18639 0.0588235294117647 0.357137382640353 0.9531593820138 1 GO:0030548 acetylcholine receptor regulator activity 1/3070 17/18639 0.0588235294117647 0.357137382640353 0.9531593820138 1 GO:0017069 snRNA binding 5/3070 54/18639 0.0925925925925926 0.562160694896851 0.955970324524166 1 GO:0022829 wide pore channel activity 3/3070 37/18639 0.0810810810810811 0.492270446342108 0.956300546209293 1 GO:0051393 alpha-actinin binding 2/3070 28/18639 0.0714285714285714 0.433666821777571 0.957859840084498 1 GO:0042562 hormone binding 10/3070 94/18639 0.106382978723404 0.645886755838936 0.958897864486675 1 GO:0140299 molecular sensor activity 7/3070 71/18639 0.0985915492957746 0.598582373721154 0.959869546285278 1 GO:0008186 ATP-dependent activity, acting on RNA 8/3070 79/18639 0.10126582278481 0.614818785304911 0.960401352932834 1 GO:0015373 monoatomic anion:sodium symporter activity 1/3070 18/18639 0.0555555555555556 0.337296416938111 0.960881468643466 1 GO:0017128 phospholipid scramblase activity 1/3070 18/18639 0.0555555555555556 0.337296416938111 0.960881468643466 1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/3070 18/18639 0.0555555555555556 0.337296416938111 0.960881468643466 1 GO:0099602 neurotransmitter receptor regulator activity 1/3070 18/18639 0.0555555555555556 0.337296416938111 0.960881468643466 1 GO:0004867 serine-type endopeptidase inhibitor activity 10/3070 95/18639 0.105263157894737 0.639087947882736 0.962431985835606 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 66/3070 484/18639 0.136363636363636 0.827909387029908 0.963787202253173 1 GO:0001216 DNA-binding transcription activator activity 67/3070 491/18639 0.136456211812627 0.828471443640248 0.964312258224525 1 GO:0005229 intracellularly calcium-gated chloride channel activity 1/3070 19/18639 0.0526315789473684 0.319543973941368 0.967330847906908 1 GO:0042577 lipid phosphatase activity 1/3070 19/18639 0.0526315789473684 0.319543973941368 0.967330847906908 1 GO:0141147 intracellularly calcium-gated channel activity 1/3070 19/18639 0.0526315789473684 0.319543973941368 0.967330847906908 1 GO:0005539 glycosaminoglycan binding 30/3070 242/18639 0.12396694214876 0.752644897299917 0.968363689021043 1 GO:0098918 structural constituent of synapse 2/3070 30/18639 0.0666666666666667 0.404755700325733 0.968835149235973 1 GO:0005004 GPI-linked ephrin receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0005008 hepatocyte growth factor receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0005009 insulin receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0005011 macrophage colony-stimulating factor receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0005020 stem cell factor receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0008288 boss receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0036332 placental growth factor receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0038062 protein tyrosine kinase collagen receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0060175 brain-derived neurotrophic factor receptor activity 4/3070 49/18639 0.0816326530612245 0.495619224888653 0.970912652525089 1 GO:0015103 inorganic anion transmembrane transporter activity 19/3070 165/18639 0.115151515151515 0.699123482380811 0.970952912925205 1 GO:0099094 ligand-gated monoatomic cation channel activity 15/3070 136/18639 0.110294117647059 0.669632592450661 0.971789203223699 1 GO:0043024 ribosomal small subunit binding 1/3070 20/18639 0.05 0.3035667752443 0.972717222607542 1 GO:0140939 histone H4 methyltransferase activity 1/3070 20/18639 0.05 0.3035667752443 0.972717222607542 1 GO:0005006 epidermal growth factor receptor activity 4/3070 50/18639 0.08 0.48570684039088 0.974345225943912 1 GO:0005007 fibroblast growth factor receptor activity 4/3070 50/18639 0.08 0.48570684039088 0.974345225943912 1 GO:0005017 platelet-derived growth factor receptor activity 4/3070 50/18639 0.08 0.48570684039088 0.974345225943912 1 GO:0005019 platelet-derived growth factor beta-receptor activity 4/3070 50/18639 0.08 0.48570684039088 0.974345225943912 1 GO:0048020 CCR chemokine receptor binding 4/3070 50/18639 0.08 0.48570684039088 0.974345225943912 1 GO:0015079 potassium ion transmembrane transporter activity 18/3070 160/18639 0.1125 0.683025244299674 0.975554831030165 1 GO:0098631 cell adhesion mediator activity 7/3070 76/18639 0.0921052631578947 0.559201954397394 0.976156543565201 1 GO:0005248 voltage-gated sodium channel activity 1/3070 21/18639 0.0476190476190476 0.289111214518381 0.977215752420896 1 GO:0036122 BMP binding 1/3070 21/18639 0.0476190476190476 0.289111214518381 0.977215752420896 1 GO:0005272 sodium channel activity 4/3070 51/18639 0.0784313725490196 0.476183176853803 0.977394606393137 1 GO:0008649 rRNA methyltransferase activity 1/3070 22/18639 0.0454545454545455 0.275969795676636 0.980972742434208 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/3070 22/18639 0.0454545454545455 0.275969795676636 0.980972742434208 1 GO:0016493 C-C chemokine receptor activity 1/3070 23/18639 0.0434782608695652 0.263971108908087 0.984110395156289 1 GO:0031681 G-protein beta-subunit binding 1/3070 23/18639 0.0434782608695652 0.263971108908087 0.984110395156289 1 GO:0140102 catalytic activity, acting on a rRNA 1/3070 23/18639 0.0434782608695652 0.263971108908087 0.984110395156289 1 GO:0005540 hyaluronic acid binding 1/3070 24/18639 0.0416666666666667 0.252972312703583 0.986730780140722 1 GO:0140612 DNA damage sensor activity 1/3070 24/18639 0.0416666666666667 0.252972312703583 0.986730780140722 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/3070 46/18639 0.0652173913043478 0.39595666336213 0.987306507884343 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/3070 36/18639 0.0555555555555556 0.337296416938111 0.987624957036922 1 GO:0005267 potassium channel activity 12/3070 124/18639 0.0967741935483871 0.587548597247032 0.989173990641614 1 GO:0008509 monoatomic anion transmembrane transporter activity 15/3070 149/18639 0.100671140939597 0.611208272303959 0.990600921022305 1 GO:0016500 protein-hormone receptor activity 5/3070 67/18639 0.0746268656716418 0.453084739170596 0.990666698064286 1 GO:0008143 poly(A) binding 1/3070 26/18639 0.0384615384615385 0.233512904034077 0.990746710413201 1 GO:0005109 frizzled binding 2/3070 38/18639 0.0526315789473684 0.319543973941368 0.990951194066071 1 GO:0005261 monoatomic cation channel activity 41/3070 341/18639 0.120234604105572 0.72998462082207 0.991541187512638 1 GO:0005253 monoatomic anion channel activity 9/3070 103/18639 0.087378640776699 0.530505044116252 0.992195824772009 1 GO:0005104 fibroblast growth factor receptor binding 1/3070 27/18639 0.037037037037037 0.22486427795874 0.992272933968323 1 GO:0008527 taste receptor activity 1/3070 28/18639 0.0357142857142857 0.216833410888785 0.993547493001057 1 GO:0045499 chemorepellent activity 1/3070 28/18639 0.0357142857142857 0.216833410888785 0.993547493001057 1 GO:0001664 G protein-coupled receptor binding 34/3070 297/18639 0.114478114478114 0.69503504096338 0.994318968745955 1 GO:0004497 monooxygenase activity 9/3070 106/18639 0.0849056603773585 0.515490750414848 0.994339606527346 1 GO:0017147 Wnt-protein binding 1/3070 31/18639 0.032258064516129 0.195849532415677 0.996242989509285 1 GO:0022843 voltage-gated monoatomic cation channel activity 13/3070 143/18639 0.0909090909090909 0.551939591353272 0.996257277363864 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/3070 44/18639 0.0454545454545455 0.275969795676636 0.996506138426675 1 GO:0070717 poly-purine tract binding 1/3070 32/18639 0.03125 0.189729234527687 0.996862831631302 1 GO:0015108 chloride transmembrane transporter activity 10/3070 121/18639 0.0826446280991736 0.501763264866611 0.997215955054364 1 GO:0042923 neuropeptide binding 1/3070 33/18639 0.0303030303030303 0.183979863784424 0.997380438278903 1 GO:0015081 sodium ion transmembrane transporter activity 15/3070 164/18639 0.0914634146341463 0.555305076666402 0.997661224057088 1 GO:0015020 glucuronosyltransferase activity 1/3070 34/18639 0.0294117647058824 0.178568691320176 0.997812667370796 1 GO:0005249 voltage-gated potassium channel activity 7/3070 98/18639 0.0714285714285714 0.433666821777571 0.998092925739377 1 GO:0008083 growth factor activity 14/3070 162/18639 0.0864197530864197 0.524683315237061 0.99873292600236 1 GO:0005254 chloride channel activity 5/3070 83/18639 0.0602409638554217 0.365743102703975 0.998839317902999 1 GO:0022834 ligand-gated channel activity 17/3070 188/18639 0.0904255319148936 0.549003742463095 0.998901800590728 1 GO:0000217 DNA secondary structure binding 1/3070 39/18639 0.0256410256410256 0.155675269356051 0.999112278762908 1 GO:0005216 monoatomic ion channel activity 51/3070 448/18639 0.113839285714286 0.691156497208004 0.999135564668428 1 GO:0017046 peptide hormone binding 2/3070 53/18639 0.0377358490566038 0.229107000184377 0.999184843014162 1 GO:0022832 voltage-gated channel activity 15/3070 175/18639 0.0857142857142857 0.520400186133085 0.9992156147101 1 GO:0071855 neuropeptide receptor binding 1/3070 40/18639 0.025 0.15178338762215 0.999258800493976 1 GO:0008227 G protein-coupled amine receptor activity 1/3070 41/18639 0.024390243902439 0.148081353777707 0.999381144839559 1 GO:0015276 ligand-gated monoatomic ion channel activity 16/3070 186/18639 0.0860215053763441 0.522265419775139 0.999404094961392 1 GO:0008307 structural constituent of muscle 1/3070 42/18639 0.0238095238095238 0.14455560725919 0.999483300197262 1 GO:0015370 solute:sodium symporter activity 4/3070 79/18639 0.0506329113924051 0.307409392652455 0.999513071325306 1 GO:0005244 voltage-gated monoatomic ion channel activity 14/3070 173/18639 0.0809248554913295 0.491321948372277 0.999597913470303 1 GO:0099095 ligand-gated monoatomic anion channel activity 1/3070 47/18639 0.0212765957446809 0.129177351167787 0.999790388346544 1 GO:0005201 extracellular matrix structural constituent 12/3070 168/18639 0.0714285714285714 0.433666821777571 0.999900290091022 1 GO:0005179 hormone activity 8/3070 132/18639 0.0606060606060606 0.367959727568848 0.999913997865401 1 GO:0022836 gated channel activity 29/3070 318/18639 0.0911949685534591 0.553675250445578 0.999952358424714 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/3070 73/18639 0.0273972602739726 0.166337959037972 0.999970397728593 1 GO:0005125 cytokine activity 17/3070 234/18639 0.0726495726495727 0.441079929842145 0.99999138730844 1 GO:0030594 neurotransmitter receptor activity 2/3070 97/18639 0.0206185567010309 0.125182175358474 0.99999949515534 1 GO:0001653 peptide receptor activity 4/3070 128/18639 0.03125 0.189729234527687 0.999999725370407 1 GO:0003730 mRNA 3'-UTR binding 16/3070 262/18639 0.0610687022900763 0.370768580451053 0.9999998975368 1 GO:0008528 G protein-coupled peptide receptor activity 3/3070 122/18639 0.0245901639344262 0.149295135366049 0.999999914741688 1 GO:0003735 structural constituent of ribosome 7/3070 175/18639 0.04 0.24285342019544 0.999999950783219 1 GO:0030371 translation repressor activity 7/3070 329/18639 0.0212765957446809 0.129177351167787 1 1 GO:0045182 translation regulator activity 8/3070 356/18639 0.0224719101123595 0.136434505727775 1 1