ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	171/3305	489/18639	0.349693251533742	1.97214296984491	1.77532899507678e-20	1.49652029847182e-17
GO:0060589	nucleoside-triphosphatase regulator activity	171/3305	490/18639	0.348979591836735	1.9681181882738	2.26060468047102e-20	1.49652029847182e-17
GO:0005201	extracellular matrix structural constituent	79/3305	168/18639	0.470238095238095	2.65197212016425	1.8374820289143e-18	8.10942068760844e-16
GO:0019838	growth factor binding	61/3305	136/18639	0.448529411764706	2.52954302749844	1.99879579072222e-13	6.61601406729053e-11
GO:0005096	GTPase activator activity	98/3305	271/18639	0.361623616236162	2.03942589501538	2.68192782685928e-13	7.10174488552337e-11
GO:0005518	collagen binding	38/3305	72/18639	0.527777777777778	2.97647503782148	1.61420494903589e-11	3.56201225420587e-09
GO:0019955	cytokine binding	59/3305	144/18639	0.409722222222222	2.3106845688351	4.89989094345385e-11	9.2677937273327e-09
GO:0140297	DNA-binding transcription factor binding	144/3305	488/18639	0.295081967213115	1.66415515488207	7.23871558544685e-11	1.19800742939145e-08
GO:0046332	SMAD binding	39/3305	79/18639	0.493670886075949	2.784124552366	1.24672581315079e-10	1.83407219623516e-08
GO:0005085	guanyl-nucleotide exchange factor activity	78/3305	230/18639	0.339130434782609	1.91257251858186	2.25298505537372e-09	2.98295221331481e-07
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	105/3305	349/18639	0.300859598853868	1.69673889955741	8.73911891333161e-09	1.05187213102282e-06
GO:0050840	extracellular matrix binding	32/3305	67/18639	0.477611940298507	2.69355792896335	1.58384753074402e-08	1.74751177558757e-06
GO:0005178	integrin binding	58/3305	161/18639	0.360248447204969	2.03167044098439	2.19530657564397e-08	2.23583531242509e-06
GO:0005539	glycosaminoglycan binding	78/3305	242/18639	0.322314049586777	1.81773421187532	2.87073019334149e-08	2.71489055427438e-06
GO:0140375	immune receptor activity	56/3305	156/18639	0.358974358974359	2.02448504596765	4.39304969209905e-08	3.7659968832032e-06
GO:0003779	actin binding	124/3305	443/18639	0.279909706546275	1.57858911356007	4.59358730949561e-08	3.7659968832032e-06
GO:0001540	amyloid-beta binding	36/3305	83/18639	0.433734939759036	2.44610757705557	4.83549448749656e-08	3.7659968832032e-06
GO:0023023	MHC protein complex binding	21/3305	37/18639	0.567567567567568	3.20087500511101	1.08108877705271e-07	7.95200856009885e-06
GO:0008201	heparin binding	58/3305	172/18639	0.337209302325581	1.90173802906097	3.05301992261148e-07	2.12747283028295e-05
GO:0001217	DNA-binding transcription repressor activity	83/3305	278/18639	0.298561151079137	1.68377648864267	4.37215303604255e-07	2.89436530986017e-05
GO:0038024	cargo receptor activity	29/3305	65/18639	0.446153846153846	2.51614569998836	4.61984838579202e-07	2.91270441085173e-05
GO:0043394	proteoglycan binding	20/3305	37/18639	0.540540540540541	3.04845238582001	6.35506278938192e-07	3.82459233324621e-05
GO:0031267	small GTPase binding	83/3305	283/18639	0.293286219081272	1.6540277874299	9.82715187619986e-07	5.6570213409081e-05
GO:0003712	transcription coregulator activity	130/3305	495/18639	0.262626262626263	1.48111676523174	1.06632302631337e-06	5.79441847388581e-05
GO:1901681	sulfur compound binding	81/3305	275/18639	0.294545454545455	1.66112941823683	1.09411224960079e-06	5.79441847388581e-05
GO:0005044	scavenger receptor activity	16/3305	27/18639	0.592592592592593	3.34200706001009	1.64822227140116e-06	8.08239365679678e-05
GO:0023026	MHC class II protein complex binding	16/3305	27/18639	0.592592592592593	3.34200706001009	1.64822227140116e-06	8.08239365679678e-05
GO:0042277	peptide binding	74/3305	249/18639	0.29718875502008	1.67603667316771	2.1767921299529e-06	0.000102931170716344
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	78/3305	268/18639	0.291044776119403	1.64138686296204	2.83581508008714e-06	0.000129469626415013
GO:0001221	transcription coregulator binding	41/3305	115/18639	0.356521739130435	2.01065316056042	3.28393524639739e-06	0.000144931008874338
GO:0004674	protein serine/threonine kinase activity	114/3305	433/18639	0.263279445727483	1.48480048076083	4.24968250925245e-06	0.000178644082498844
GO:0051020	GTPase binding	88/3305	315/18639	0.279365079365079	1.57551761400475	4.31768175223791e-06	0.000178644082498844
GO:0030020	extracellular matrix structural constituent conferring tensile strength	21/3305	44/18639	0.477272727272727	2.69164489066153	4.70418505153593e-06	0.000188737606310108
GO:0015026	coreceptor activity	26/3305	61/18639	0.426229508196721	2.40377966816299	5.09192365322043e-06	0.000198285497554819
GO:0003714	transcription corepressor activity	62/3305	204/18639	0.303921568627451	1.71400729732135	6.40520805083332e-06	0.000242299870265809
GO:0048407	platelet-derived growth factor binding	9/3305	11/18639	0.818181818181818	4.6142483839912	6.6790933522651e-06	0.000245642211066639
GO:0140996	histone H3 kinase activity	96/3305	357/18639	0.26890756302521	1.51654101882811	9.38373319837026e-06	0.00032173142190742
GO:0004896	cytokine receptor activity	35/3305	96/18639	0.364583333333333	2.05611762481089	9.51261123849399e-06	0.00032173142190742
GO:0050431	transforming growth factor beta binding	14/3305	24/18639	0.583333333333333	3.28978819969743	9.67987434487626e-06	0.00032173142190742
GO:0005024	transforming growth factor beta receptor activity	11/3305	16/18639	0.6875	3.87725037821483	9.71998253496737e-06	0.00032173142190742
GO:0016922	nuclear receptor binding	45/3305	137/18639	0.328467153284672	1.8524354826242	1.33699638048046e-05	0.000427876005301859
GO:0035173	histone kinase activity	96/3305	360/18639	0.266666666666667	1.50390317700454	1.35731059083671e-05	0.000427876005301859
GO:0106310	protein serine kinase activity	95/3305	361/18639	0.263157894736842	1.48411497730711	2.64456972475417e-05	0.000814281468738262
GO:0141003	histone H2AX kinase activity	93/3305	354/18639	0.26271186440678	1.48159952819303	3.42972151551413e-05	0.00103203438330471
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	11/3305	18/18639	0.611111111111111	3.4464447806354	4.98660630069022e-05	0.0014352753787204
GO:0030228	lipoprotein particle receptor activity	11/3305	18/18639	0.611111111111111	3.4464447806354	4.98660630069022e-05	0.0014352753787204
GO:0001968	fibronectin binding	15/3305	30/18639	0.5	2.81981845688351	5.47400815583531e-05	0.00153168124909435
GO:0004713	protein tyrosine kinase activity	44/3305	140/18639	0.314285714285714	1.77245731575535	5.55292295744174e-05	0.00153168124909435
GO:0042169	SH2 domain binding	18/3305	41/18639	0.439024390243902	2.47593815726357	8.94377531996898e-05	0.00240068838406167
GO:0008432	JUN kinase binding	8/3305	11/18639	0.727272727272727	4.10155411910329	9.59454874051256e-05	0.00240068838406167
GO:0097493	structural molecule activity conferring elasticity	8/3305	11/18639	0.727272727272727	4.10155411910329	9.59454874051256e-05	0.00240068838406167
GO:0030246	carbohydrate binding	75/3305	280/18639	0.267857142857143	1.51061703047331	9.70049175139604e-05	0.00240068838406167
GO:0046966	nuclear thyroid hormone receptor binding	14/3305	28/18639	0.5	2.81981845688351	9.71155152737558e-05	0.00240068838406167
GO:0019199	transmembrane receptor protein kinase activity	28/3305	78/18639	0.358974358974359	2.02448504596765	9.82528067227178e-05	0.00240068838406167
GO:0070851	growth factor receptor binding	43/3305	139/18639	0.309352517985612	1.74463587979843	0.000100737150885125	0.00240068838406167
GO:0042974	nuclear retinoic acid receptor binding	13/3305	25/18639	0.52	2.93261119515885	0.00010301447760532	0.00240068838406167
GO:0005543	phospholipid binding	121/3305	497/18639	0.243460764587525	1.37303031502175	0.000103352898709604	0.00240068838406167
GO:0019003	GDP binding	27/3305	75/18639	0.36	2.03026928895613	0.000122892953756769	0.0028053494961028
GO:0005161	platelet-derived growth factor receptor binding	9/3305	14/18639	0.642857142857143	3.62548087313594	0.000144970293749217	0.00325323167667735
GO:0043548	phosphatidylinositol 3-kinase binding	13/3305	26/18639	0.5	2.81981845688351	0.000172660181710015	0.00378404708514032
GO:0046965	nuclear retinoid X receptor binding	10/3305	17/18639	0.588235294117647	3.31743347868648	0.000174340537910543	0.00378404708514032
GO:0033218	amide binding	66/3305	247/18639	0.267206477732794	1.50694751541953	0.000264844498894473	0.00558145620591616
GO:0001223	transcription coactivator binding	18/3305	44/18639	0.409090909090909	2.3071241919956	0.000265582885931056	0.00558145620591616
GO:0005126	cytokine receptor binding	72/3305	275/18639	0.261818181818182	1.47655948287718	0.000277956273300986	0.00575022040391414
GO:0038187	pattern recognition receptor activity	19/3305	48/18639	0.395833333333333	2.23235627836611	0.000300755023890083	0.00612424952951329
GO:0005041	low-density lipoprotein particle receptor activity	9/3305	15/18639	0.6	3.38378214826021	0.000305287363253684	0.00612424952951329
GO:0004715	non-membrane spanning protein tyrosine kinase activity	18/3305	45/18639	0.4	2.25585476550681	0.000369889689518573	0.00730946192421776
GO:0098531	ligand-modulated transcription factor activity	22/3305	60/18639	0.366666666666667	2.06786686838124	0.000376394638899693	0.00732862502798815
GO:0032395	MHC class II receptor activity	7/3305	10/18639	0.7	3.94774583963691	0.000397735682503952	0.00763191367587294
GO:0019787	ubiquitin-like protein transferase activity	114/3305	479/18639	0.237995824634656	1.34221003793203	0.000411510348795573	0.00778342431150483
GO:0035091	phosphatidylinositol binding	73/3305	284/18639	0.257042253521127	1.44962498135561	0.000453873667529192	0.00846378501138944
GO:0016755	aminoacyltransferase activity	117/3305	496/18639	0.235887096774194	1.33031757844908	0.000499218119011509	0.00918006652182275
GO:0070123	transforming growth factor beta receptor activity, type III	8/3305	13/18639	0.615384615384615	3.4705457930874	0.000533103066337376	0.00966888301137925
GO:0030021	extracellular matrix structural constituent conferring compression resistance	11/3305	22/18639	0.5	2.81981845688351	0.000550046009203056	0.00984136373222765
GO:0043395	heparan sulfate proteoglycan binding	10/3305	19/18639	0.526315789473684	2.96822995461422	0.000586055188166111	0.0102619493835033
GO:0035401	histone H3Y41 kinase activity	35/3305	115/18639	0.304347826086957	1.71641123462475	0.000596805213391051	0.0102619493835033
GO:0140801	histone H2AXY142 kinase activity	35/3305	115/18639	0.304347826086957	1.71641123462475	0.000596805213391051	0.0102619493835033
GO:0003713	transcription coactivator activity	66/3305	256/18639	0.2578125	1.45396889183056	0.000759500278675792	0.0126586889629321
GO:0140313	molecular sequestering activity	20/3305	55/18639	0.363636363636364	2.05077705955164	0.000772853230180008	0.0126586889629321
GO:0005160	transforming growth factor beta receptor binding	12/3305	26/18639	0.461538461538462	2.60290934481555	0.000774436409363672	0.0126586889629321
GO:0050681	nuclear androgen receptor binding	12/3305	26/18639	0.461538461538462	2.60290934481555	0.000774436409363672	0.0126586889629321
GO:0004879	nuclear receptor activity	21/3305	59/18639	0.355932203389831	2.00732839303572	0.000798669365225337	0.0128955882872969
GO:0140311	protein sequestering activity	14/3305	33/18639	0.424242424242424	2.39257323614358	0.000817738318849118	0.0130444040259787
GO:1990782	protein tyrosine kinase binding	35/3305	117/18639	0.299145299145299	1.68707087163971	0.000844331278775398	0.0133082692035551
GO:0004954	prostanoid receptor activity	7/3305	11/18639	0.636363636363636	3.58885985421538	0.000925868523926899	0.0139301127918093
GO:0005114	type II transforming growth factor beta receptor binding	7/3305	11/18639	0.636363636363636	3.58885985421538	0.000925868523926899	0.0139301127918093
GO:0042608	T cell receptor binding	7/3305	11/18639	0.636363636363636	3.58885985421538	0.000925868523926899	0.0139301127918093
GO:0048185	activin binding	7/3305	11/18639	0.636363636363636	3.58885985421538	0.000925868523926899	0.0139301127918093
GO:0016004	phospholipase activator activity	10/3305	20/18639	0.5	2.81981845688351	0.000986571806053223	0.0146766412496008
GO:0002020	protease binding	39/3305	136/18639	0.286764705882353	1.61724882085966	0.00109072542869382	0.0160457829732291
GO:0042605	peptide antigen binding	17/3305	45/18639	0.377777777777778	2.13052950075643	0.00115030430232201	0.0167362955634542
GO:0000149	SNARE binding	32/3305	106/18639	0.30188679245283	1.7025318984957	0.00116428965158259	0.0167556467249495
GO:0001618	virus receptor activity	26/3305	81/18639	0.320987654320988	1.81025382417213	0.00122364949939601	0.0174205584645196
GO:0004842	ubiquitin-protein transferase activity	105/3305	449/18639	0.233853006681514	1.31884604887647	0.00128136989359138	0.0180482312671807
GO:0140272	exogenous protein binding	26/3305	82/18639	0.317073170731707	1.78817755802369	0.00149417953363023	0.0208241442371203
GO:0051019	mitogen-activated protein kinase binding	12/3305	28/18639	0.428571428571429	2.41698724875729	0.00172104684778462	0.0237361044423629
GO:0034185	apolipoprotein binding	9/3305	18/18639	0.5	2.81981845688351	0.00177691163698094	0.0239727132796602
GO:1901981	phosphatidylinositol phosphate binding	49/3305	185/18639	0.264864864864865	1.49374166905181	0.00186474152230035	0.0239727132796602
GO:0005025	transforming growth factor beta receptor activity, type I	7/3305	12/18639	0.583333333333333	3.28978819969743	0.0018820532034325	0.0239727132796602
GO:0005026	transforming growth factor beta receptor activity, type II	7/3305	12/18639	0.583333333333333	3.28978819969743	0.0018820532034325	0.0239727132796602
GO:0016361	activin receptor activity, type I	7/3305	12/18639	0.583333333333333	3.28978819969743	0.0018820532034325	0.0239727132796602
GO:0016362	activin receptor activity, type II	7/3305	12/18639	0.583333333333333	3.28978819969743	0.0018820532034325	0.0239727132796602
GO:0017002	activin receptor activity	7/3305	12/18639	0.583333333333333	3.28978819969743	0.0018820532034325	0.0239727132796602
GO:0004953	icosanoid receptor activity	8/3305	15/18639	0.533333333333333	3.00780635400908	0.00190241464868491	0.0239727132796602
GO:0008375	acetylglucosaminyltransferase activity	16/3305	43/18639	0.372093023255814	2.09846954930866	0.00191619784558808	0.0239727132796602
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	111/3305	484/18639	0.229338842975207	1.29338780460359	0.00191926556468579	0.0239727132796602
GO:0019902	phosphatase binding	50/3305	190/18639	0.263157894736842	1.48411497730711	0.00195564565815915	0.0241988303869413
GO:0042826	histone deacetylase binding	36/3305	127/18639	0.283464566929134	1.59863723539853	0.00206584385304172	0.0253257153835856
GO:0001216	DNA-binding transcription activator activity	112/3305	491/18639	0.228105906313646	1.28643448949472	0.0022197988853667	0.0269634286626194
GO:0045296	cadherin binding	80/3305	334/18639	0.239520958083832	1.35081123683042	0.00230154430678515	0.0277022242016686
GO:0008238	exopeptidase activity	30/3305	102/18639	0.294117647058824	1.65871673934324	0.00254515968229042	0.0303584812554281
GO:0035591	signaling adaptor activity	36/3305	129/18639	0.27906976744186	1.57385216198149	0.00276298947664583	0.0326624827417775
GO:0070412	R-SMAD binding	11/3305	26/18639	0.423076923076923	2.38600023274759	0.00301346781377266	0.0350392128955341
GO:0042805	actinin binding	14/3305	37/18639	0.378378378378378	2.13391667007401	0.0030169715030898	0.0350392128955341
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	15/3305	41/18639	0.365853658536585	2.06328179771964	0.00317908299368778	0.0364021133400554
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	8/3305	16/18639	0.5	2.81981845688351	0.00321680306705928	0.0364021133400554
GO:0070411	I-SMAD binding	8/3305	16/18639	0.5	2.81981845688351	0.00321680306705928	0.0364021133400554
GO:0008083	growth factor activity	43/3305	162/18639	0.265432098765432	1.49694066229618	0.00326334014774013	0.0366157826746435
GO:0051018	protein kinase A binding	18/3305	53/18639	0.339622641509434	1.91534838580767	0.00333410096246031	0.0366816296457196
GO:0004955	prostaglandin receptor activity	6/3305	10/18639	0.6	3.38378214826021	0.003380029317808	0.0366816296457196
GO:0008239	dipeptidyl-peptidase activity	6/3305	10/18639	0.6	3.38378214826021	0.003380029317808	0.0366816296457196
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	6/3305	10/18639	0.6	3.38378214826021	0.003380029317808	0.0366816296457196
GO:0051015	actin filament binding	53/3305	209/18639	0.253588516746411	1.43014715995049	0.00344435576409405	0.0370758295256953
GO:0008194	UDP-glycosyltransferase activity	39/3305	145/18639	0.268965517241379	1.51686785956492	0.0038483478168876	0.041090423464187
GO:0008013	beta-catenin binding	30/3305	106/18639	0.283018867924528	1.59612365483972	0.00475932012186032	0.0504107187307445
GO:0017124	SH3 domain binding	32/3305	115/18639	0.278260869565217	1.56929027165691	0.00481463124668154	0.0505918394492568
GO:0051219	phosphoprotein binding	27/3305	93/18639	0.290322580645161	1.63731394270655	0.00493210841308148	0.0507843705566191
GO:0005154	epidermal growth factor receptor binding	13/3305	35/18639	0.371428571428571	2.09472228225632	0.00505721714991224	0.0507843705566191
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	8/3305	17/18639	0.470588235294118	2.65394678294919	0.00513980789621372	0.0507843705566191
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	8/3305	17/18639	0.470588235294118	2.65394678294919	0.00513980789621372	0.0507843705566191
GO:0008429	phosphatidylethanolamine binding	8/3305	17/18639	0.470588235294118	2.65394678294919	0.00513980789621372	0.0507843705566191
GO:0016805	dipeptidase activity	8/3305	17/18639	0.470588235294118	2.65394678294919	0.00513980789621372	0.0507843705566191
GO:0019198	transmembrane receptor protein phosphatase activity	8/3305	17/18639	0.470588235294118	2.65394678294919	0.00513980789621372	0.0507843705566191
GO:0030169	low-density lipoprotein particle binding	8/3305	17/18639	0.470588235294118	2.65394678294919	0.00513980789621372	0.0507843705566191
GO:0098631	cell adhesion mediator activity	23/3305	76/18639	0.302631578947368	1.70673222390318	0.00521604513711787	0.050998147730648
GO:0035035	histone acetyltransferase binding	10/3305	24/18639	0.416666666666667	2.34984871406959	0.00527699867001418	0.050998147730648
GO:0060229	lipase activator activity	10/3305	24/18639	0.416666666666667	2.34984871406959	0.00527699867001418	0.050998147730648
GO:0001784	phosphotyrosine residue binding	16/3305	47/18639	0.340425531914894	1.91987639617601	0.00535543718865278	0.0513811509983788
GO:0035403	histone H3T6 kinase activity	60/3305	247/18639	0.242914979757085	1.36995228674502	0.00546579470887421	0.0520626776586292
GO:0019209	kinase activator activity	39/3305	148/18639	0.263513513513513	1.48612053808726	0.00559851347115275	0.0529459416843303
GO:0098821	BMP receptor activity	7/3305	14/18639	0.5	2.81981845688351	0.00586104329696536	0.0550356122353343
GO:0036408	histone H3K14 acetyltransferase activity	11/3305	28/18639	0.392857142857143	2.21557164469419	0.00593642108159941	0.0553508557185748
GO:0003924	GTPase activity	77/3305	331/18639	0.232628398791541	1.31193970501529	0.00601325361759466	0.0556751593684988
GO:0031625	ubiquitin protein ligase binding	71/3305	302/18639	0.235099337748344	1.32587490356774	0.00624880859331091	0.0574543234551642
GO:0071813	lipoprotein particle binding	12/3305	32/18639	0.375	2.11486384266263	0.0063822918789499	0.0578083796540308
GO:0071814	protein-lipid complex binding	12/3305	32/18639	0.375	2.11486384266263	0.0063822918789499	0.0578083796540308
GO:0044389	ubiquitin-like protein ligase binding	75/3305	322/18639	0.232919254658385	1.31358002649853	0.00642764855637614	0.0578083796540308
GO:0010314	phosphatidylinositol-5-phosphate binding	9/3305	21/18639	0.428571428571429	2.41698724875729	0.00646196388881915	0.0578083796540308
GO:0005080	protein kinase C binding	17/3305	52/18639	0.326923076923077	1.84372745257768	0.00660630688789653	0.0587030222790269
GO:0032266	phosphatidylinositol-3-phosphate binding	16/3305	48/18639	0.333333333333333	1.87987897125567	0.00673545076732467	0.0594515787729191
GO:0005516	calmodulin binding	51/3305	207/18639	0.246376811594203	1.38947576136289	0.00739769281768891	0.0648645383484776
GO:0140857	histone H3T45 kinase activity	59/3305	246/18639	0.239837398373984	1.35259584517177	0.00772877302522802	0.0673216808250125
GO:0010484	histone H3 acetyltransferase activity	11/3305	29/18639	0.379310344827586	2.13917262246335	0.00805654048091747	0.069265322056719
GO:0043236	laminin binding	11/3305	29/18639	0.379310344827586	2.13917262246335	0.00805654048091747	0.069265322056719
GO:0031490	chromatin DNA binding	34/3305	128/18639	0.265625	1.49802855521936	0.00812635823706062	0.0694148277797952
GO:0035402	histone H3T11 kinase activity	59/3305	247/18639	0.238866396761134	1.34711974863261	0.00843896302876459	0.0707187527162829
GO:0071889	14-3-3 protein binding	12/3305	33/18639	0.363636363636364	2.05077705955164	0.00843924692535703	0.0707187527162829
GO:0140416	transcription regulator inhibitor activity	12/3305	33/18639	0.363636363636364	2.05077705955164	0.00843924692535703	0.0707187527162829
GO:0004197	cysteine-type endopeptidase activity	25/3305	88/18639	0.284090909090909	1.60216957777472	0.0089418185428047	0.0729768808338103
GO:0019207	kinase regulator activity	67/3305	287/18639	0.233449477351916	1.31657028997349	0.009083763812028	0.0729768808338103
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	58/3305	243/18639	0.238683127572016	1.34608617694851	0.00909679842626748	0.0729768808338103
GO:0004679	AMP-activated protein kinase activity	59/3305	248/18639	0.237903225806452	1.34168781416232	0.00920328914335387	0.0729768808338103
GO:0033691	sialic acid binding	9/3305	22/18639	0.409090909090909	2.3071241919956	0.0092400767079801	0.0729768808338103
GO:0120283	protein serine/threonine kinase binding	7/3305	15/18639	0.466666666666667	2.63183055975794	0.00932484336421078	0.0729768808338103
GO:0034237	protein kinase A regulatory subunit binding	10/3305	26/18639	0.384615384615385	2.16909112067962	0.0101700866097809	0.0729768808338103
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	25/3305	89/18639	0.280898876404494	1.58416767240647	0.0103889139364985	0.0729768808338103
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	25/3305	89/18639	0.280898876404494	1.58416767240647	0.0103889139364985	0.0729768808338103
GO:0004180	carboxypeptidase activity	15/3305	46/18639	0.326086956521739	1.83901203709794	0.010665084725026	0.0729768808338103
GO:0001965	G-protein alpha-subunit binding	11/3305	30/18639	0.366666666666667	2.06786686838124	0.010719739985651	0.0729768808338103
GO:0043995	histone H4K5 acetyltransferase activity	11/3305	30/18639	0.366666666666667	2.06786686838124	0.010719739985651	0.0729768808338103
GO:0043996	histone H4K8 acetyltransferase activity	11/3305	30/18639	0.366666666666667	2.06786686838124	0.010719739985651	0.0729768808338103
GO:0043997	histone H4K12 acetyltransferase activity	11/3305	30/18639	0.366666666666667	2.06786686838124	0.010719739985651	0.0729768808338103
GO:0005078	MAP-kinase scaffold activity	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0035259	nuclear glucocorticoid receptor binding	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0070008	serine-type exopeptidase activity	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/3305	12/18639	0.5	2.81981845688351	0.0107679913374982	0.0729768808338103
GO:0004676	3-phosphoinositide-dependent protein kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0004711	ribosomal protein S6 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0035175	histone H3S10 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0035979	histone H2AXS139 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0044022	histone H3S28 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0044023	histone H4S1 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0044024	histone H2AS1 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0044025	histone H2BS14 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0072354	histone H3T3 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0072371	histone H2AS121 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0072518	Rho-dependent protein serine/threonine kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0140823	histone H2BS36 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0140855	histone H3S57 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0140995	histone H2A kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0140997	histone H4 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0140998	histone H2B kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:1990244	histone H2AT120 kinase activity	58/3305	245/18639	0.236734693877551	1.33509771836117	0.0108032240509266	0.0729768808338103
GO:0004677	DNA-dependent protein kinase activity	58/3305	246/18639	0.235772357723577	1.32967049186377	0.0117517248992805	0.0789811358713062
GO:0030971	receptor tyrosine kinase binding	23/3305	81/18639	0.283950617283951	1.6013783829215	0.0119015267878504	0.0795839468036056
GO:0140793	histone H2AXY142 phosphatase activity	25/3305	90/18639	0.277777777777778	1.56656580937973	0.0120199701694586	0.0799720628359962
GO:0005158	insulin receptor binding	9/3305	23/18639	0.391304347826087	2.20681444451753	0.0128327848436013	0.0845303837459112
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	9/3305	23/18639	0.391304347826087	2.20681444451753	0.0128327848436013	0.0845303837459112
GO:0016757	glycosyltransferase activity	62/3305	267/18639	0.232209737827715	1.30957860918935	0.0131087532087513	0.0859207388533998
GO:0061659	ubiquitin-like protein ligase activity	83/3305	372/18639	0.223118279569892	1.25830608559856	0.0133534712722541	0.0870935761796276
GO:0004683	calcium/calmodulin-dependent protein kinase activity	10/3305	27/18639	0.37037037037037	2.0887544125063	0.0136346192013995	0.0884731026216695
GO:0043130	ubiquitin binding	27/3305	100/18639	0.27	1.5227019667171	0.0136986299376452	0.0884731026216695
GO:0017147	Wnt-protein binding	11/3305	31/18639	0.354838709677419	2.00116148553023	0.0140074153374963	0.0887429370380611
GO:0070273	phosphatidylinositol-4-phosphate binding	11/3305	31/18639	0.354838709677419	2.00116148553023	0.0140074153374963	0.0887429370380611
GO:0005159	insulin-like growth factor receptor binding	7/3305	16/18639	0.4375	2.46734114977307	0.0140755413731064	0.0887429370380611
GO:0005521	lamin binding	7/3305	16/18639	0.4375	2.46734114977307	0.0140755413731064	0.0887429370380611
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	7/3305	16/18639	0.4375	2.46734114977307	0.0140755413731064	0.0887429370380611
GO:0001972	retinoic acid binding	8/3305	20/18639	0.4	2.25585476550681	0.0161735019114488	0.101008096843199
GO:0042288	MHC class I protein binding	8/3305	20/18639	0.4	2.25585476550681	0.0161735019114488	0.101008096843199
GO:0030295	protein kinase activator activity	35/3305	139/18639	0.251798561151079	1.42005246030105	0.0169466571369371	0.104710577285389
GO:0017154	semaphorin receptor activity	6/3305	13/18639	0.461538461538462	2.60290934481555	0.0170355596010308	0.104710577285389
GO:0035325	Toll-like receptor binding	6/3305	13/18639	0.461538461538462	2.60290934481555	0.0170355596010308	0.104710577285389
GO:0061134	peptidase regulator activity	53/3305	226/18639	0.234513274336283	1.32256971871527	0.0170826923668006	0.104710577285389
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	13/3305	40/18639	0.325	1.83288199697428	0.017334588093274	0.105764952237303
GO:0005484	SNAP receptor activity	12/3305	36/18639	0.333333333333333	1.87987897125567	0.0177759420137673	0.10683649846271
GO:0016798	hydrolase activity, acting on glycosyl bonds	33/3305	130/18639	0.253846153846154	1.43160013964855	0.0177837422404583	0.10683649846271
GO:0050698	proteoglycan sulfotransferase activity	10/3305	28/18639	0.357142857142857	2.01415604063108	0.0179113959346218	0.10683649846271
GO:0051393	alpha-actinin binding	10/3305	28/18639	0.357142857142857	2.01415604063108	0.0179113959346218	0.10683649846271
GO:0140030	modification-dependent protein binding	42/3305	173/18639	0.242774566473988	1.36916040681049	0.017913672702962	0.10683649846271
GO:0034212	protein N-acetyltransferase activity	16/3305	53/18639	0.30188679245283	1.7025318984957	0.0184466485845952	0.109032869312518
GO:0038064	collagen receptor activity	16/3305	53/18639	0.30188679245283	1.7025318984957	0.0184466485845952	0.109032869312518
GO:0004725	protein tyrosine phosphatase activity	26/3305	98/18639	0.26530612244898	1.49623020161166	0.0191685835815252	0.112593773692671
GO:0001664	G protein-coupled receptor binding	67/3305	297/18639	0.225589225589226	1.27224132398111	0.0192191788931598	0.112593773692671
GO:0001222	transcription corepressor binding	15/3305	49/18639	0.306122448979592	1.72641946339807	0.0194614389526017	0.113510771688302
GO:0042578	phosphoric ester hydrolase activity	80/3305	363/18639	0.220385674931129	1.24289518760706	0.0198571784080945	0.113676257633109
GO:0005131	growth hormone receptor binding	5/3305	10/18639	0.5	2.81981845688351	0.0200049607466121	0.113676257633109
GO:0042975	peroxisome proliferator activated receptor binding	5/3305	10/18639	0.5	2.81981845688351	0.0200049607466121	0.113676257633109
GO:0043422	protein kinase B binding	5/3305	10/18639	0.5	2.81981845688351	0.0200049607466121	0.113676257633109
GO:0070513	death domain binding	5/3305	10/18639	0.5	2.81981845688351	0.0200049607466121	0.113676257633109
GO:0140999	histone H3K4 trimethyltransferase activity	5/3305	10/18639	0.5	2.81981845688351	0.0200049607466121	0.113676257633109
GO:0005092	GDP-dissociation inhibitor activity	7/3305	17/18639	0.411764705882353	2.32220343508054	0.0203305548069312	0.115032711813577
GO:0046915	transition metal ion transmembrane transporter activity	14/3305	45/18639	0.311111111111111	1.75455370650529	0.0204469281561016	0.115198863313525
GO:0004175	endopeptidase activity	88/3305	405/18639	0.217283950617284	1.22540258867036	0.0214925672212682	0.120576944919318
GO:0005125	cytokine activity	54/3305	234/18639	0.230769230769231	1.30145467240777	0.0218545832537877	0.122090583240569
GO:0036122	BMP binding	8/3305	21/18639	0.380952380952381	2.14843311000648	0.0221498330022978	0.122704514205198
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	8/3305	21/18639	0.380952380952381	2.14843311000648	0.0221498330022978	0.122704514205198
GO:0019956	chemokine binding	11/3305	33/18639	0.333333333333333	1.87987897125567	0.0227826679752809	0.125684384996966
GO:0003707	nuclear steroid receptor activity	9/3305	25/18639	0.36	2.03026928895613	0.0229624090889227	0.12615033043043
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	10/3305	29/18639	0.344827586206897	1.94470238405759	0.023098161962887	0.12637176214406
GO:0045309	protein phosphorylated amino acid binding	17/3305	59/18639	0.288135593220339	1.62498012769558	0.024395711981825	0.132921492444182
GO:0030276	clathrin binding	14/3305	46/18639	0.304347826086957	1.71641123462475	0.0247264846571971	0.133718010738004
GO:1990841	promoter-specific chromatin binding	19/3305	68/18639	0.279411764705882	1.57578090237608	0.0247438917151139	0.133718010738004
GO:0061665	SUMO ligase activity	6/3305	14/18639	0.428571428571429	2.41698724875729	0.0254164468290798	0.136794209763015
GO:0005109	frizzled binding	12/3305	38/18639	0.315789473684211	1.78093797276853	0.0273165674189073	0.146256512154574
GO:0061630	ubiquitin protein ligase activity	77/3305	353/18639	0.218130311614731	1.23017575739394	0.0274386736900552	0.146256512154574
GO:0008081	phosphoric diester hydrolase activity	23/3305	87/18639	0.264367816091954	1.49093849444415	0.0275059452616986	0.146256512154574
GO:0005010	insulin-like growth factor receptor activity	15/3305	51/18639	0.294117647058824	1.65871673934324	0.0278322916604678	0.146352770267861
GO:0005021	vascular endothelial growth factor receptor activity	15/3305	51/18639	0.294117647058824	1.65871673934324	0.0278322916604678	0.146352770267861
GO:0019903	protein phosphatase binding	35/3305	144/18639	0.243055555555556	1.37074508320726	0.0281876504454366	0.146352770267861
GO:0070064	proline-rich region binding	7/3305	18/18639	0.388888888888889	2.19319213313162	0.0282853738363239	0.146352770267861
GO:0004714	transmembrane receptor protein tyrosine kinase activity	17/3305	60/18639	0.283333333333333	1.59789712556732	0.0285815874624587	0.146352770267861
GO:0032931	histone H3K56 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0043992	histone H3K9 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0043993	histone H3K18 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0043994	histone H3K23 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0043999	histone H2AK5 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0044012	histone H2AK9 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0044014	histone H2BK5 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0044015	histone H2BK12 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0044016	histone H3K4 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0044017	histone H3K27 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0044018	histone H3K36 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0046972	histone H4K16 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0140908	histone H3K122 acetyltransferase activity	8/3305	22/18639	0.363636363636364	2.05077705955164	0.0295268365990507	0.146352770267861
GO:0061733	protein-lysine-acetyltransferase activity	14/3305	47/18639	0.297872340425532	1.67989184665401	0.0296360312357713	0.146352770267861
GO:0097602	cullin family protein binding	9/3305	26/18639	0.346153846153846	1.95218200861166	0.0297348151072919	0.146352770267861
GO:0061135	endopeptidase regulator activity	43/3305	184/18639	0.233695652173913	1.31795862658686	0.0308550783124252	0.150652536765204
GO:0019215	intermediate filament binding	5/3305	11/18639	0.454545454545455	2.56347132443955	0.0314049094767343	0.150652536765204
GO:0019864	IgG binding	5/3305	11/18639	0.454545454545455	2.56347132443955	0.0314049094767343	0.150652536765204
GO:0032050	clathrin heavy chain binding	5/3305	11/18639	0.454545454545455	2.56347132443955	0.0314049094767343	0.150652536765204
GO:0034713	type I transforming growth factor beta receptor binding	5/3305	11/18639	0.454545454545455	2.56347132443955	0.0314049094767343	0.150652536765204
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/3305	11/18639	0.454545454545455	2.56347132443955	0.0314049094767343	0.150652536765204
GO:0140031	phosphorylation-dependent protein binding	5/3305	11/18639	0.454545454545455	2.56347132443955	0.0314049094767343	0.150652536765204
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/3305	39/18639	0.307692307692308	1.7352728965437	0.0332773451783532	0.158496276919111
GO:0019905	syntaxin binding	17/3305	61/18639	0.278688524590164	1.57170209072196	0.0332794297458556	0.158496276919111
GO:0019887	protein kinase regulator activity	57/3305	255/18639	0.223529411764706	1.26062472190086	0.0339700643116628	0.161205609851762
GO:0003725	double-stranded RNA binding	20/3305	75/18639	0.266666666666667	1.50390317700454	0.0348848663246166	0.164955582192116
GO:0010485	histone H4 acetyltransferase activity	11/3305	35/18639	0.314285714285714	1.77245731575535	0.0350097907493115	0.164957163530564
GO:0051371	muscle alpha-actinin binding	6/3305	15/18639	0.4	2.25585476550681	0.0361441824723259	0.169698218416168
GO:0005385	zinc ion transmembrane transporter activity	9/3305	27/18639	0.333333333333333	1.87987897125567	0.0377849130602383	0.175454338172614
GO:0005520	insulin-like growth factor binding	7/3305	19/18639	0.368421052631579	2.07776096822995	0.0381042631538189	0.175454338172614
GO:0015245	fatty acid transmembrane transporter activity	7/3305	19/18639	0.368421052631579	2.07776096822995	0.0381042631538189	0.175454338172614
GO:0042800	histone H3K4 methyltransferase activity	7/3305	19/18639	0.368421052631579	2.07776096822995	0.0381042631538189	0.175454338172614
GO:0140036	ubiquitin-modified protein reader activity	7/3305	19/18639	0.368421052631579	2.07776096822995	0.0381042631538189	0.175454338172614
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	8/3305	23/18639	0.347826086956522	1.96161283957114	0.0384303308686238	0.175454338172614
GO:0044013	histone H2B acetyltransferase activity	8/3305	23/18639	0.347826086956522	1.96161283957114	0.0384303308686238	0.175454338172614
GO:0140103	catalytic activity, acting on a glycoprotein	8/3305	23/18639	0.347826086956522	1.96161283957114	0.0384303308686238	0.175454338172614
GO:1901505	carbohydrate derivative transmembrane transporter activity	15/3305	53/18639	0.283018867924528	1.59612365483972	0.0386014596225965	0.175630008729614
GO:0140034	methylation-dependent protein binding	20/3305	76/18639	0.263157894736842	1.48411497730711	0.0397096238223046	0.180053225824422
GO:0016763	pentosyltransferase activity	14/3305	49/18639	0.285714285714286	1.61132483250486	0.0415254236357106	0.187643893835088
GO:0004222	metalloendopeptidase activity	27/3305	110/18639	0.245454545454545	1.38427451519736	0.0440321403766551	0.198294400879903
GO:0141110	transporter inhibitor activity	13/3305	45/18639	0.288888888888889	1.62922844175492	0.0446188824639299	0.200255594516079
GO:0043425	bHLH transcription factor binding	10/3305	32/18639	0.3125	1.76238653555219	0.0450008230705195	0.20097608040983
GO:0030414	peptidase inhibitor activity	39/3305	169/18639	0.230769230769231	1.30145467240777	0.0455048584743972	0.20097608040983
GO:0032182	ubiquitin-like protein binding	29/3305	120/18639	0.241666666666667	1.36291225416036	0.0456024881190048	0.20097608040983
GO:0008237	metallopeptidase activity	42/3305	184/18639	0.228260869565217	1.28730842596856	0.0458436977973816	0.20097608040983
GO:0004875	complement receptor activity	5/3305	12/18639	0.416666666666667	2.34984871406959	0.0461455652904744	0.20097608040983
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/3305	12/18639	0.416666666666667	2.34984871406959	0.0461455652904744	0.20097608040983
GO:0035497	cAMP response element binding	5/3305	12/18639	0.416666666666667	2.34984871406959	0.0461455652904744	0.20097608040983
GO:0070410	co-SMAD binding	5/3305	12/18639	0.416666666666667	2.34984871406959	0.0461455652904744	0.20097608040983
GO:0070679	inositol 1,4,5 trisphosphate binding	5/3305	12/18639	0.416666666666667	2.34984871406959	0.0461455652904744	0.20097608040983
GO:0019789	SUMO transferase activity	9/3305	28/18639	0.321428571428571	1.81274043656797	0.0471986843302671	0.204219143964947
GO:0045499	chemorepellent activity	9/3305	28/18639	0.321428571428571	1.81274043656797	0.0471986843302671	0.204219143964947
GO:0001786	phosphatidylserine binding	16/3305	59/18639	0.271186440677966	1.52939306136055	0.0480422812825769	0.207192118625836
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	8/3305	24/18639	0.333333333333333	1.87987897125567	0.0489623680290587	0.209129715822253
GO:0043998	histone H2A acetyltransferase activity	8/3305	24/18639	0.333333333333333	1.87987897125567	0.0489623680290587	0.209129715822253
GO:0004721	phosphoprotein phosphatase activity	40/3305	175/18639	0.228571428571429	1.28905986600389	0.0493753412105889	0.209129715822253
GO:0005324	long-chain fatty acid transmembrane transporter activity	6/3305	16/18639	0.375	2.11486384266263	0.0493853671318576	0.209129715822253
GO:0031435	mitogen-activated protein kinase kinase kinase binding	6/3305	16/18639	0.375	2.11486384266263	0.0493853671318576	0.209129715822253
GO:0043178	alcohol binding	23/3305	92/18639	0.25	1.40990922844175	0.0496332838155341	0.209129715822253
GO:0001614	purinergic nucleotide receptor activity	7/3305	20/18639	0.35	1.97387291981846	0.0499131345920182	0.209129715822253
GO:0016502	nucleotide receptor activity	7/3305	20/18639	0.35	1.97387291981846	0.0499131345920182	0.209129715822253
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	7/3305	20/18639	0.35	1.97387291981846	0.0499131345920182	0.209129715822253
GO:0044325	transmembrane transporter binding	32/3305	136/18639	0.235294117647059	1.32697339147459	0.0517357863013673	0.216082590104134
GO:0004866	endopeptidase inhibitor activity	37/3305	161/18639	0.229813664596273	1.29606562614522	0.0530791335015692	0.220535127407787
GO:0008080	N-acetyltransferase activity	18/3305	69/18639	0.260869565217391	1.47120962967835	0.0531349740506677	0.220535127407787
GO:0019239	deaminase activity	10/3305	33/18639	0.303030303030303	1.7089808829597	0.054660890503232	0.226159434457123
GO:0035064	methylated histone binding	19/3305	74/18639	0.256756756756757	1.44801488326451	0.0552368269595379	0.227265192106436
GO:0051213	dioxygenase activity	23/3305	93/18639	0.247311827956989	1.39474891415743	0.0552714440017164	0.227265192106436
GO:0004402	histone acetyltransferase activity	12/3305	42/18639	0.285714285714286	1.61132483250486	0.0565883410138376	0.231959639326071
GO:0004629	phospholipase C activity	9/3305	29/18639	0.310344827586207	1.75023214565183	0.0580439193955881	0.237191818764687
GO:0097110	scaffold protein binding	18/3305	70/18639	0.257142857142857	1.45019234925438	0.0601137609058019	0.244894213659328
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	8/3305	25/18639	0.32	1.80468381240545	0.0611976428244171	0.247029509449781
GO:0019211	phosphatase activator activity	8/3305	25/18639	0.32	1.80468381240545	0.0611976428244171	0.247029509449781
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/3305	25/18639	0.32	1.80468381240545	0.0611976428244171	0.247029509449781
GO:0005525	GTP binding	79/3305	378/18639	0.208994708994709	1.17865427562856	0.0614314538830284	0.247219589486716
GO:0051010	microtubule plus-end binding	7/3305	21/18639	0.333333333333333	1.87987897125567	0.0637947853868784	0.255811586043853
GO:0005035	death receptor activity	5/3305	13/18639	0.384615384615385	2.16909112067962	0.0643393188463768	0.255811586043853
GO:0032396	inhibitory MHC class I receptor activity	5/3305	13/18639	0.384615384615385	2.16909112067962	0.0643393188463768	0.255811586043853
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	5/3305	13/18639	0.384615384615385	2.16909112067962	0.0643393188463768	0.255811586043853
GO:0030159	signaling receptor complex adaptor activity	14/3305	52/18639	0.269230769230769	1.51836378447574	0.0651135586265067	0.257050843078352
GO:0008484	sulfuric ester hydrolase activity	6/3305	17/18639	0.352941176470588	1.99046008721189	0.0652334465818173	0.257050843078352
GO:0045125	bioactive lipid receptor activity	6/3305	17/18639	0.352941176470588	1.99046008721189	0.0652334465818173	0.257050843078352
GO:0008376	acetylgalactosaminyltransferase activity	10/3305	34/18639	0.294117647058824	1.65871673934324	0.0655912235751232	0.257693709238763
GO:0004857	enzyme inhibitor activity	86/3305	416/18639	0.206730769230769	1.1658864773653	0.0658220910013624	0.257835646407703
GO:0004712	protein serine/threonine/tyrosine kinase activity	12/3305	43/18639	0.27906976744186	1.57385216198149	0.0663135760657367	0.258232866797163
GO:0048156	tau protein binding	12/3305	43/18639	0.27906976744186	1.57385216198149	0.0663135760657367	0.258232866797163
GO:0017022	myosin binding	19/3305	76/18639	0.25	1.40990922844175	0.069619400673461	0.270311104081121
GO:0031624	ubiquitin conjugating enzyme binding	9/3305	30/18639	0.3	1.69189107413011	0.0703681535859093	0.271625175940944
GO:0035925	mRNA 3'-UTR AU-rich region binding	9/3305	30/18639	0.3	1.69189107413011	0.0703681535859093	0.271625175940944
GO:0005246	calcium channel regulator activity	14/3305	53/18639	0.264150943396226	1.48971541118374	0.0746307223715001	0.285214341765568
GO:0008146	sulfotransferase activity	14/3305	53/18639	0.264150943396226	1.48971541118374	0.0746307223715001	0.285214341765568
GO:0001637	G protein-coupled chemoattractant receptor activity	8/3305	26/18639	0.307692307692308	1.7352728965437	0.0751811218098059	0.285214341765568
GO:0004950	chemokine receptor activity	8/3305	26/18639	0.307692307692308	1.7352728965437	0.0751811218098059	0.285214341765568
GO:0008157	protein phosphatase 1 binding	8/3305	26/18639	0.307692307692308	1.7352728965437	0.0751811218098059	0.285214341765568
GO:0030247	polysaccharide binding	8/3305	26/18639	0.307692307692308	1.7352728965437	0.0751811218098059	0.285214341765568
GO:0016248	channel inhibitor activity	12/3305	44/18639	0.272727272727273	1.53808279466373	0.0770677145497621	0.291536154468243
GO:0061631	ubiquitin conjugating enzyme activity	10/3305	35/18639	0.285714285714286	1.61132483250486	0.0778237967054478	0.292723598971628
GO:0140566	histone reader activity	10/3305	35/18639	0.285714285714286	1.61132483250486	0.0778237967054478	0.292723598971628
GO:0140789	histone phosphatase activity	31/3305	136/18639	0.227941176470588	1.28550547299101	0.0782303578879467	0.293419246015982
GO:0031683	G-protein beta/gamma-subunit complex binding	7/3305	22/18639	0.318181818181818	1.79442992710769	0.0797864948211978	0.295275671780517
GO:0140035	ubiquitin-like protein reader activity	7/3305	22/18639	0.318181818181818	1.79442992710769	0.0797864948211978	0.295275671780517
GO:0005004	GPI-linked ephrin receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0005008	hepatocyte growth factor receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0005009	insulin receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0005011	macrophage colony-stimulating factor receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0005018	platelet-derived growth factor alpha-receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0005020	stem cell factor receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0008288	boss receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0036332	placental growth factor receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0038062	protein tyrosine kinase collagen receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0060175	brain-derived neurotrophic factor receptor activity	13/3305	49/18639	0.26530612244898	1.49623020161166	0.0814015258307315	0.295275671780517
GO:0032934	sterol binding	17/3305	68/18639	0.25	1.40990922844175	0.0828389293152734	0.296984127070658
GO:0017075	syntaxin-1 binding	6/3305	18/18639	0.333333333333333	1.87987897125567	0.0837074829545642	0.296984127070658
GO:0032393	MHC class I receptor activity	6/3305	18/18639	0.333333333333333	1.87987897125567	0.0837074829545642	0.296984127070658
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0005031	tumor necrosis factor receptor activity	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0005381	iron ion transmembrane transporter activity	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0015279	store-operated calcium channel activity	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0043208	glycosphingolipid binding	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0070097	delta-catenin binding	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0071723	lipopeptide binding	4/3305	10/18639	0.4	2.25585476550681	0.0843399031560176	0.296984127070658
GO:0003925	G protein activity	14/3305	54/18639	0.259259259259259	1.46212808875441	0.0850080844080097	0.297753184540224
GO:0140463	chromatin-protein adaptor activity	14/3305	54/18639	0.259259259259259	1.46212808875441	0.0850080844080097	0.297753184540224
GO:0004705	JUN kinase activity	5/3305	14/18639	0.357142857142857	2.01415604063108	0.085963136633764	0.298727540428093
GO:0008191	metalloendopeptidase inhibitor activity	5/3305	14/18639	0.357142857142857	2.01415604063108	0.085963136633764	0.298727540428093
GO:0042813	Wnt receptor activity	5/3305	14/18639	0.357142857142857	2.01415604063108	0.085963136633764	0.298727540428093
GO:0030165	PDZ domain binding	20/3305	83/18639	0.240963855421687	1.35894865391976	0.0876612289734374	0.30383106586605
GO:0008009	chemokine activity	12/3305	45/18639	0.266666666666667	1.50390317700454	0.0888672898537013	0.307207028110445
GO:0044390	ubiquitin-like protein conjugating enzyme binding	10/3305	36/18639	0.277777777777778	1.56656580937973	0.0913742245948697	0.315050711884394
GO:0043177	organic acid binding	41/3305	189/18639	0.216931216931217	1.22341329875369	0.0927944522112416	0.315488839308283
GO:0005006	epidermal growth factor receptor activity	13/3305	50/18639	0.26	1.46630559757943	0.0929310025152796	0.315488839308283
GO:0005007	fibroblast growth factor receptor activity	13/3305	50/18639	0.26	1.46630559757943	0.0929310025152796	0.315488839308283
GO:0005017	platelet-derived growth factor receptor activity	13/3305	50/18639	0.26	1.46630559757943	0.0929310025152796	0.315488839308283
GO:0005019	platelet-derived growth factor beta-receptor activity	13/3305	50/18639	0.26	1.46630559757943	0.0929310025152796	0.315488839308283
GO:0032813	tumor necrosis factor receptor superfamily binding	13/3305	50/18639	0.26	1.46630559757943	0.0929310025152796	0.315488839308283
GO:0098632	cell-cell adhesion mediator activity	14/3305	55/18639	0.254545454545455	1.43554394168615	0.0962555686094892	0.325939572478168
GO:0042287	MHC protein binding	11/3305	41/18639	0.268292682926829	1.51307331832774	0.0971141605707894	0.328008032131952
GO:0005212	structural constituent of eye lens	7/3305	23/18639	0.304347826086957	1.71641123462475	0.0978798165504491	0.328915931758362
GO:0017134	fibroblast growth factor binding	7/3305	23/18639	0.304347826086957	1.71641123462475	0.0978798165504491	0.328915931758362
GO:0042562	hormone binding	22/3305	94/18639	0.234042553191489	1.319915022371	0.0982427598353845	0.329299782334301
GO:0016791	phosphatase activity	57/3305	273/18639	0.208791208791209	1.17750660836894	0.0999146416285957	0.334058044232982
GO:0030291	protein serine/threonine kinase inhibitor activity	12/3305	46/18639	0.260869565217391	1.47120962967835	0.101718586884449	0.339232768350153
GO:0019001	guanyl nucleotide binding	81/3305	400/18639	0.2025	1.14202647503782	0.103920026393572	0.344158269652811
GO:0032561	guanyl ribonucleotide binding	81/3305	400/18639	0.2025	1.14202647503782	0.103920026393572	0.344158269652811
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	6/3305	19/18639	0.315789473684211	1.78093797276853	0.1047551228626	0.344158269652811
GO:0005346	purine ribonucleotide transmembrane transporter activity	6/3305	19/18639	0.315789473684211	1.78093797276853	0.1047551228626	0.344158269652811
GO:0070003	threonine-type peptidase activity	6/3305	19/18639	0.315789473684211	1.78093797276853	0.1047551228626	0.344158269652811
GO:0097001	ceramide binding	6/3305	19/18639	0.315789473684211	1.78093797276853	0.1047551228626	0.344158269652811
GO:0005030	neurotrophin receptor activity	13/3305	51/18639	0.254901960784314	1.43755450743081	0.105414786419989	0.345468260445706
GO:0170055	lipid transmembrane transporter activity	14/3305	56/18639	0.25	1.40990922844175	0.108376117358705	0.350967401807642
GO:0051959	dynein light intermediate chain binding	8/3305	28/18639	0.285714285714286	1.61132483250486	0.108418177748735	0.350967401807642
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/3305	28/18639	0.285714285714286	1.61132483250486	0.108418177748735	0.350967401807642
GO:0097718	disordered domain specific binding	8/3305	28/18639	0.285714285714286	1.61132483250486	0.108418177748735	0.350967401807642
GO:0141052	histone H3 demethylase activity	8/3305	28/18639	0.285714285714286	1.61132483250486	0.108418177748735	0.350967401807642
GO:0008242	omega peptidase activity	5/3305	15/18639	0.333333333333333	1.87987897125567	0.110872613714483	0.355436659946671
GO:0015929	hexosaminidase activity	5/3305	15/18639	0.333333333333333	1.87987897125567	0.110872613714483	0.355436659946671
GO:0031005	filamin binding	5/3305	15/18639	0.333333333333333	1.87987897125567	0.110872613714483	0.355436659946671
GO:0042809	nuclear vitamin D receptor binding	5/3305	15/18639	0.333333333333333	1.87987897125567	0.110872613714483	0.355436659946671
GO:0042056	chemoattractant activity	11/3305	42/18639	0.261904761904762	1.47704776312946	0.111494290090998	0.355707084531281
GO:0048487	beta-tubulin binding	11/3305	42/18639	0.261904761904762	1.47704776312946	0.111494290090998	0.355707084531281
GO:0008235	metalloexopeptidase activity	16/3305	66/18639	0.242424242424242	1.36718470636776	0.112600961912662	0.357818715962081
GO:0031406	carboxylic acid binding	40/3305	187/18639	0.213903743315508	1.20633944679508	0.112761843331151	0.357818715962081
GO:0001851	complement component C3b binding	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0003953	NAD+ nucleosidase activity	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0008046	axon guidance receptor activity	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0016176	superoxide-generating NADPH oxidase activator activity	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0047676	arachidonate-CoA ligase activity	4/3305	11/18639	0.363636363636364	2.05077705955164	0.114588470972751	0.357818715962081
GO:0030296	protein tyrosine kinase activator activity	9/3305	33/18639	0.272727272727273	1.53808279466373	0.116362885993404	0.362504614247687
GO:0016407	acetyltransferase activity	22/3305	96/18639	0.229166666666667	1.29241679273828	0.117060117636261	0.36382064730143
GO:0016504	peptidase activator activity	14/3305	57/18639	0.245614035087719	1.38517397881997	0.121365554018728	0.376318485997179
GO:0005501	retinoid binding	10/3305	38/18639	0.263157894736842	1.48411497730711	0.122407311505972	0.377779208470645
GO:0019840	isoprenoid binding	10/3305	38/18639	0.263157894736842	1.48411497730711	0.122407311505972	0.377779208470645
GO:0008200	ion channel inhibitor activity	11/3305	43/18639	0.255813953488372	1.4426978151497	0.127025160537182	0.3910960271828
GO:0004181	metallocarboxypeptidase activity	8/3305	29/18639	0.275862068965517	1.55576190724607	0.127608371407077	0.3910960271828
GO:0051861	glycolipid binding	8/3305	29/18639	0.275862068965517	1.55576190724607	0.127608371407077	0.3910960271828
GO:0005003	ephrin receptor activity	13/3305	53/18639	0.245283018867925	1.38330716752776	0.13321931617787	0.405476723263217
GO:0005005	transmembrane-ephrin receptor activity	13/3305	53/18639	0.245283018867925	1.38330716752776	0.13321931617787	0.405476723263217
GO:0140296	general transcription initiation factor binding	13/3305	53/18639	0.245283018867925	1.38330716752776	0.13321931617787	0.405476723263217
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	9/3305	34/18639	0.264705882352941	1.49284506540892	0.134640684463985	0.408862995941093
GO:0005496	steroid binding	24/3305	108/18639	0.222222222222222	1.25325264750378	0.136719594614597	0.414225957138962
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3305	16/18639	0.3125	1.76238653555219	0.138821362161131	0.416778874152692
GO:0004707	MAP kinase activity	5/3305	16/18639	0.3125	1.76238653555219	0.138821362161131	0.416778874152692
GO:0015923	mannosidase activity	5/3305	16/18639	0.3125	1.76238653555219	0.138821362161131	0.416778874152692
GO:0019841	retinol binding	5/3305	16/18639	0.3125	1.76238653555219	0.138821362161131	0.416778874152692
GO:0008139	nuclear localization sequence binding	7/3305	25/18639	0.28	1.57909833585477	0.140120771336858	0.418780815462753
GO:0008483	transaminase activity	7/3305	25/18639	0.28	1.57909833585477	0.140120771336858	0.418780815462753
GO:0141108	transporter regulator activity	36/3305	170/18639	0.211764705882353	1.19427605232713	0.140529771997511	0.419057248028614
GO:0043014	alpha-tubulin binding	11/3305	44/18639	0.25	1.40990922844175	0.143677642532988	0.427481345423991
GO:0032452	histone demethylase activity	8/3305	30/18639	0.266666666666667	1.50390317700454	0.14842299606932	0.433020525559536
GO:0004000	adenosine deaminase activity	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0005095	GTPase inhibitor activity	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0005247	voltage-gated chloride channel activity	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0008504	monoamine transmembrane transporter activity	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0008603	cAMP-dependent protein kinase regulator activity	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0016208	AMP binding	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0017166	vinculin binding	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0097677	STAT family protein binding	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/3305	12/18639	0.333333333333333	1.87987897125567	0.148809923813889	0.433020525559536
GO:0004860	protein kinase inhibitor activity	19/3305	84/18639	0.226190476190476	1.27563215906635	0.15105625425966	0.438593159297785
GO:0005123	death receptor binding	6/3305	21/18639	0.285714285714286	1.61132483250486	0.154044450815239	0.442418335963939
GO:0008373	sialyltransferase activity	6/3305	21/18639	0.285714285714286	1.61132483250486	0.154044450815239	0.442418335963939
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/3305	21/18639	0.285714285714286	1.61132483250486	0.154044450815239	0.442418335963939
GO:0072542	protein phosphatase activator activity	6/3305	21/18639	0.285714285714286	1.61132483250486	0.154044450815239	0.442418335963939
GO:0140312	cargo adaptor activity	6/3305	21/18639	0.285714285714286	1.61132483250486	0.154044450815239	0.442418335963939
GO:0030331	nuclear estrogen receptor binding	10/3305	40/18639	0.25	1.40990922844175	0.15848350150363	0.452224474118116
GO:0061791	GTPase motor activity	10/3305	40/18639	0.25	1.40990922844175	0.15848350150363	0.452224474118116
GO:1990606	membrane scission GTPase motor activity	10/3305	40/18639	0.25	1.40990922844175	0.15848350150363	0.452224474118116
GO:0019210	kinase inhibitor activity	20/3305	90/18639	0.222222222222222	1.25325264750378	0.163018176121384	0.463106137983022
GO:0004435	phosphatidylinositol phospholipase C activity	7/3305	26/18639	0.269230769230769	1.51836378447574	0.16404590537314	0.463106137983022
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	7/3305	26/18639	0.269230769230769	1.51836378447574	0.16404590537314	0.463106137983022
GO:0019865	immunoglobulin binding	7/3305	26/18639	0.269230769230769	1.51836378447574	0.16404590537314	0.463106137983022
GO:0052742	phosphatidylinositol kinase activity	7/3305	26/18639	0.269230769230769	1.51836378447574	0.16404590537314	0.463106137983022
GO:0048306	calcium-dependent protein binding	18/3305	80/18639	0.225	1.26891830559758	0.16469121281689	0.463938650573537
GO:0016782	transferase activity, transferring sulphur-containing groups	16/3305	70/18639	0.228571428571429	1.28905986600389	0.165614319000338	0.46554853154235
GO:0015294	solute:monoatomic cation symporter activity	25/3305	116/18639	0.21551724137931	1.215438990036	0.168130829960804	0.471621226415476
GO:0015278	intracellularly gated calcium channel activity	5/3305	17/18639	0.294117647058824	1.65871673934324	0.169482993652511	0.472411544412474
GO:0017110	nucleoside diphosphate phosphatase activity	5/3305	17/18639	0.294117647058824	1.65871673934324	0.169482993652511	0.472411544412474
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/3305	17/18639	0.294117647058824	1.65871673934324	0.169482993652511	0.472411544412474
GO:0008327	methyl-CpG binding	8/3305	31/18639	0.258064516129032	1.45539017129471	0.170762364315278	0.473981908497753
GO:0140457	protein demethylase activity	8/3305	31/18639	0.258064516129032	1.45539017129471	0.170762364315278	0.473981908497753
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	20/3305	91/18639	0.21978021978022	1.23948064038836	0.17601243530015	0.487532352170289
GO:0001530	lipopolysaccharide binding	10/3305	41/18639	0.24390243902439	1.37552119847976	0.178280063094869	0.490733479288163
GO:0001727	lipid kinase activity	10/3305	41/18639	0.24390243902439	1.37552119847976	0.178280063094869	0.490733479288163
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/3305	41/18639	0.24390243902439	1.37552119847976	0.178280063094869	0.490733479288163
GO:0019208	phosphatase regulator activity	25/3305	117/18639	0.213675213675214	1.20505062259979	0.179702711405169	0.493623215561086
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/3305	22/18639	0.272727272727273	1.53808279466373	0.181891184313004	0.497570099236399
GO:0061133	endopeptidase activator activity	6/3305	22/18639	0.272727272727273	1.53808279466373	0.181891184313004	0.497570099236399
GO:0005172	vascular endothelial growth factor receptor binding	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0008035	high-density lipoprotein particle binding	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0031994	insulin-like growth factor I binding	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0035673	oligopeptide transmembrane transporter activity	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0045159	myosin II binding	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0070700	BMP receptor binding	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0071714	icosanoid transmembrane transporter activity	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/3305	13/18639	0.307692307692308	1.7352728965437	0.186352414910561	0.501484953946308
GO:0016758	hexosyltransferase activity	40/3305	197/18639	0.203045685279188	1.14510394188163	0.194271977318615	0.521736507038229
GO:0019213	deacetylase activity	9/3305	37/18639	0.243243243243243	1.371803573619	0.197478943010666	0.528525128993087
GO:0016500	protein-hormone receptor activity	15/3305	67/18639	0.223880597014925	1.26260527920157	0.19759814112657	0.528525128993087
GO:0019894	kinesin binding	10/3305	42/18639	0.238095238095238	1.34277069375405	0.199150617158578	0.531603663544269
GO:0140938	histone H3 methyltransferase activity	11/3305	47/18639	0.234042553191489	1.319915022371	0.199895295323747	0.532517849111952
GO:0015172	acidic amino acid transmembrane transporter activity	5/3305	18/18639	0.277777777777778	1.56656580937973	0.202473574690184	0.535079866047511
GO:0016854	racemase and epimerase activity	5/3305	18/18639	0.277777777777778	1.56656580937973	0.202473574690184	0.535079866047511
GO:0035615	clathrin adaptor activity	5/3305	18/18639	0.277777777777778	1.56656580937973	0.202473574690184	0.535079866047511
GO:0050811	GABA receptor binding	5/3305	18/18639	0.277777777777778	1.56656580937973	0.202473574690184	0.535079866047511
GO:0017171	serine hydrolase activity	40/3305	198/18639	0.202020202020202	1.1393205886398	0.203826362328722	0.537581879926748
GO:0000295	adenine nucleotide transmembrane transporter activity	6/3305	23/18639	0.260869565217391	1.47120962967835	0.211542255288024	0.554617714854145
GO:0004602	glutathione peroxidase activity	6/3305	23/18639	0.260869565217391	1.47120962967835	0.211542255288024	0.554617714854145
GO:0043274	phospholipase binding	6/3305	23/18639	0.260869565217391	1.47120962967835	0.211542255288024	0.554617714854145
GO:0030145	manganese ion binding	15/3305	68/18639	0.220588235294118	1.24403755450743	0.214558773203816	0.561414655576783
GO:0005507	copper ion binding	14/3305	63/18639	0.222222222222222	1.25325264750378	0.21643551495312	0.564047099544409
GO:0046625	sphingolipid binding	7/3305	28/18639	0.25	1.40990922844175	0.216710686595126	0.564047099544409
GO:0008236	serine-type peptidase activity	39/3305	194/18639	0.201030927835052	1.13374144142739	0.216842880413976	0.564047099544409
GO:0016410	N-acyltransferase activity	20/3305	94/18639	0.212765957446809	1.19992274761	0.218036508679862	0.566039877435564
GO:0016247	channel regulator activity	34/3305	168/18639	0.202380952380952	1.14135508969094	0.222930935887357	0.573564106298605
GO:0051117	ATPase binding	18/3305	84/18639	0.214285714285714	1.20849362437865	0.22373109529074	0.573564106298605
GO:0004065	arylsulfatase activity	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0005545	1-phosphatidylinositol binding	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0008331	high voltage-gated calcium channel activity	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0019763	immunoglobulin receptor activity	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0032454	histone H3K9 demethylase activity	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0034236	protein kinase A catalytic subunit binding	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0042043	neurexin family protein binding	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0046030	inositol trisphosphate phosphatase activity	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0071933	Arp2/3 complex binding	4/3305	14/18639	0.285714285714286	1.61132483250486	0.226508126221281	0.573564106298605
GO:0033293	monocarboxylic acid binding	17/3305	79/18639	0.215189873417722	1.21359275359543	0.226566486098316	0.573564106298605
GO:1902936	phosphatidylinositol bisphosphate binding	23/3305	111/18639	0.207207207207207	1.16857341456434	0.237062309946492	0.595230834896623
GO:0005229	intracellularly calcium-gated chloride channel activity	5/3305	19/18639	0.263157894736842	1.48411497730711	0.237373021771463	0.595230834896623
GO:0016918	retinal binding	5/3305	19/18639	0.263157894736842	1.48411497730711	0.237373021771463	0.595230834896623
GO:0141147	intracellularly calcium-gated channel activity	5/3305	19/18639	0.263157894736842	1.48411497730711	0.237373021771463	0.595230834896623
GO:1990380	K48-linked deubiquitinase activity	5/3305	19/18639	0.263157894736842	1.48411497730711	0.237373021771463	0.595230834896623
GO:0015485	cholesterol binding	12/3305	54/18639	0.222222222222222	1.25325264750378	0.239781079371316	0.596206719206868
GO:0051287	NAD binding	12/3305	54/18639	0.222222222222222	1.25325264750378	0.239781079371316	0.596206719206868
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0019957	C-C chemokine binding	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0030215	semaphorin receptor binding	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	6/3305	24/18639	0.25	1.40990922844175	0.24271557526624	0.596206719206868
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	7/3305	29/18639	0.241379310344828	1.36129166884032	0.245061423245869	0.597534667361936
GO:0035250	UDP-galactosyltransferase activity	7/3305	29/18639	0.241379310344828	1.36129166884032	0.245061423245869	0.597534667361936
GO:0097472	cyclin-dependent protein kinase activity	7/3305	29/18639	0.241379310344828	1.36129166884032	0.245061423245869	0.597534667361936
GO:0099604	ligand-gated calcium channel activity	7/3305	29/18639	0.241379310344828	1.36129166884032	0.245061423245869	0.597534667361936
GO:0008028	monocarboxylic acid transmembrane transporter activity	15/3305	70/18639	0.214285714285714	1.20849362437865	0.250274326873027	0.598603463742543
GO:0072341	modified amino acid binding	19/3305	91/18639	0.208791208791209	1.17750660836894	0.25229631380805	0.598603463742543
GO:0099106	ion channel regulator activity	32/3305	160/18639	0.2	1.1279273827534	0.253621360546359	0.598603463742543
GO:0004090	carbonyl reductase (NADPH) activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0004382	GDP phosphatase activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0005345	purine nucleobase transmembrane transporter activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0005522	profilin binding	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0008140	cAMP response element binding protein binding	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0019911	structural constituent of myelin sheath	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0035256	G protein-coupled glutamate receptor binding	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0035374	chondroitin sulfate binding	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:1905394	retromer complex binding	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3305	10/18639	0.3	1.69189107413011	0.254994224736249	0.598603463742543
GO:0008234	cysteine-type peptidase activity	37/3305	187/18639	0.197860962566845	1.11586398828545	0.256270592444716	0.599743563919271
GO:0001098	basal transcription machinery binding	13/3305	60/18639	0.216666666666667	1.22192133131619	0.257291800835458	0.599743563919271
GO:0001099	basal RNA polymerase II transcription machinery binding	13/3305	60/18639	0.216666666666667	1.22192133131619	0.257291800835458	0.599743563919271
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	13/3305	60/18639	0.216666666666667	1.22192133131619	0.257291800835458	0.599743563919271
GO:0140767	enzyme-substrate adaptor activity	28/3305	139/18639	0.201438848920863	1.13604196824084	0.257872059045629	0.600039729659777
GO:0004467	long-chain fatty acid-CoA ligase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0004559	alpha-mannosidase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0005523	tropomyosin binding	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0017081	chloride channel regulator activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0047372	monoacylglycerol lipase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0141050	histone H3K deacetylase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0141051	histone H4K deacetylase activity	4/3305	15/18639	0.266666666666667	1.50390317700454	0.268557403496479	0.613216917757623
GO:0004177	aminopeptidase activity	9/3305	40/18639	0.225	1.26891830559758	0.270193528516813	0.613216917757623
GO:0032451	demethylase activity	9/3305	40/18639	0.225	1.26891830559758	0.270193528516813	0.613216917757623
GO:0005343	organic acid:sodium symporter activity	8/3305	35/18639	0.228571428571429	1.28905986600389	0.272680451208604	0.613216917757623
GO:0005326	neurotransmitter transmembrane transporter activity	5/3305	20/18639	0.25	1.40990922844175	0.273744418321477	0.613216917757623
GO:0016505	peptidase activator activity involved in apoptotic process	5/3305	20/18639	0.25	1.40990922844175	0.273744418321477	0.613216917757623
GO:0031418	L-ascorbic acid binding	5/3305	20/18639	0.25	1.40990922844175	0.273744418321477	0.613216917757623
GO:0043024	ribosomal small subunit binding	5/3305	20/18639	0.25	1.40990922844175	0.273744418321477	0.613216917757623
GO:0015215	nucleotide transmembrane transporter activity	7/3305	30/18639	0.233333333333333	1.31591527987897	0.274473118473515	0.613216917757623
GO:0016769	transferase activity, transferring nitrogenous groups	7/3305	30/18639	0.233333333333333	1.31591527987897	0.274473118473515	0.613216917757623
GO:0033612	receptor serine/threonine kinase binding	7/3305	30/18639	0.233333333333333	1.31591527987897	0.274473118473515	0.613216917757623
GO:0051721	protein phosphatase 2A binding	7/3305	30/18639	0.233333333333333	1.31591527987897	0.274473118473515	0.613216917757623
GO:0001848	complement binding	6/3305	25/18639	0.24	1.35351285930408	0.275113934401834	0.613216917757623
GO:0004709	MAP kinase kinase kinase activity	6/3305	25/18639	0.24	1.35351285930408	0.275113934401834	0.613216917757623
GO:0015296	monoatomic anion:monoatomic cation symporter activity	6/3305	25/18639	0.24	1.35351285930408	0.275113934401834	0.613216917757623
GO:0017025	TBP-class protein binding	6/3305	25/18639	0.24	1.35351285930408	0.275113934401834	0.613216917757623
GO:0120020	cholesterol transfer activity	6/3305	25/18639	0.24	1.35351285930408	0.275113934401834	0.613216917757623
GO:0015293	symporter activity	29/3305	146/18639	0.198630136986301	1.12020185273454	0.2797430976603	0.622487161852499
GO:0042379	chemokine receptor binding	15/3305	72/18639	0.208333333333333	1.1749243570348	0.288057048756973	0.639911967372874
GO:0015179	L-amino acid transmembrane transporter activity	13/3305	62/18639	0.209677419354839	1.18250451417696	0.29874511619273	0.662543607770811
GO:0004190	aspartic-type endopeptidase activity	8/3305	36/18639	0.222222222222222	1.25325264750378	0.3005074324913	0.663708748883182
GO:0004869	cysteine-type endopeptidase inhibitor activity	8/3305	36/18639	0.222222222222222	1.25325264750378	0.3005074324913	0.663708748883182
GO:0005164	tumor necrosis factor receptor binding	7/3305	31/18639	0.225806451612903	1.27346639988288	0.304722088436334	0.663708748883182
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0004016	adenylate cyclase activity	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0005225	volume-sensitive anion channel activity	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0015205	nucleobase transmembrane transporter activity	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0045294	alpha-catenin binding	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0050786	RAGE receptor binding	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0050998	nitric-oxide synthase binding	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0099528	G protein-coupled neurotransmitter receptor activity	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3305	11/18639	0.272727272727273	1.53808279466373	0.307646382397561	0.663708748883182
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/3305	26/18639	0.230769230769231	1.30145467240777	0.308434343110442	0.663708748883182
GO:0005227	calcium-activated cation channel activity	6/3305	26/18639	0.230769230769231	1.30145467240777	0.308434343110442	0.663708748883182
GO:0015216	purine nucleotide transmembrane transporter activity	6/3305	26/18639	0.230769230769231	1.30145467240777	0.308434343110442	0.663708748883182
GO:0019200	carbohydrate kinase activity	5/3305	21/18639	0.238095238095238	1.34277069375405	0.311150658167176	0.663708748883182
GO:0035613	RNA stem-loop binding	5/3305	21/18639	0.238095238095238	1.34277069375405	0.311150658167176	0.663708748883182
GO:0004708	MAP kinase kinase activity	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0005149	interleukin-1 receptor binding	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0008142	oxysterol binding	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0022841	potassium ion leak channel activity	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0022858	alanine transmembrane transporter activity	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0034450	ubiquitin-ubiquitin ligase activity	4/3305	16/18639	0.25	1.40990922844175	0.311802750608262	0.663708748883182
GO:0005504	fatty acid binding	10/3305	47/18639	0.212765957446809	1.19992274761	0.316223149246643	0.670960656414352
GO:0043495	protein-membrane adaptor activity	10/3305	47/18639	0.212765957446809	1.19992274761	0.316223149246643	0.670960656414352
GO:0042393	histone binding	47/3305	247/18639	0.190283400809717	1.0731292912836	0.320210288631513	0.678333475436996
GO:0048029	monosaccharide binding	15/3305	74/18639	0.202702702702703	1.1431696446825	0.327475728993108	0.692616398062102
GO:0070001	aspartic-type peptidase activity	8/3305	37/18639	0.216216216216216	1.219380954328	0.328929084761819	0.694580714871847
GO:0008378	galactosyltransferase activity	7/3305	32/18639	0.21875	1.23367057488654	0.335582930298014	0.706378059959572
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/3305	32/18639	0.21875	1.23367057488654	0.335582930298014	0.706378059959572
GO:0019888	protein phosphatase regulator activity	21/3305	107/18639	0.196261682242991	1.10684462793558	0.340776383693006	0.716171320650063
GO:0005104	fibroblast growth factor receptor binding	6/3305	27/18639	0.222222222222222	1.25325264750378	0.342376281318132	0.717256639976592
GO:0008266	poly(U) RNA binding	6/3305	27/18639	0.222222222222222	1.25325264750378	0.342376281318132	0.717256639976592
GO:0004407	histone deacetylase activity	5/3305	22/18639	0.227272727272727	1.28173566221978	0.349168150477227	0.720095978907941
GO:0005243	gap junction channel activity	5/3305	22/18639	0.227272727272727	1.28173566221978	0.349168150477227	0.720095978907941
GO:0015377	chloride:monoatomic cation symporter activity	5/3305	22/18639	0.227272727272727	1.28173566221978	0.349168150477227	0.720095978907941
GO:0033558	protein lysine deacetylase activity	5/3305	22/18639	0.227272727272727	1.28173566221978	0.349168150477227	0.720095978907941
GO:0050321	tau-protein kinase activity	5/3305	22/18639	0.227272727272727	1.28173566221978	0.349168150477227	0.720095978907941
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/3305	59/18639	0.203389830508475	1.14704479602041	0.349719946020591	0.720095978907941
GO:0031593	polyubiquitin modification-dependent protein binding	12/3305	59/18639	0.203389830508475	1.14704479602041	0.349719946020591	0.720095978907941
GO:0070063	RNA polymerase binding	12/3305	59/18639	0.203389830508475	1.14704479602041	0.349719946020591	0.720095978907941
GO:0070888	E-box binding	12/3305	59/18639	0.203389830508475	1.14704479602041	0.349719946020591	0.720095978907941
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	17/3305	86/18639	0.197674418604651	1.11481194807022	0.351946562961348	0.720095978907941
GO:0004550	nucleoside diphosphate kinase activity	4/3305	17/18639	0.235294117647059	1.32697339147459	0.355593445056186	0.720095978907941
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3305	17/18639	0.235294117647059	1.32697339147459	0.355593445056186	0.720095978907941
GO:0038191	neuropilin binding	4/3305	17/18639	0.235294117647059	1.32697339147459	0.355593445056186	0.720095978907941
GO:0070403	NAD+ binding	4/3305	17/18639	0.235294117647059	1.32697339147459	0.355593445056186	0.720095978907941
GO:1990226	histone methyltransferase binding	4/3305	17/18639	0.235294117647059	1.32697339147459	0.355593445056186	0.720095978907941
GO:0000146	microfilament motor activity	8/3305	38/18639	0.210526315789474	1.18729198184569	0.357769631219209	0.720095978907941
GO:0042887	amide transmembrane transporter activity	8/3305	38/18639	0.210526315789474	1.18729198184569	0.357769631219209	0.720095978907941
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/3305	54/18639	0.203703703703704	1.14881492687847	0.358032573113873	0.720095978907941
GO:0050661	NADP binding	11/3305	54/18639	0.203703703703704	1.14881492687847	0.358032573113873	0.720095978907941
GO:0015101	organic cation transmembrane transporter activity	16/3305	81/18639	0.197530864197531	1.1140023533367	0.359792339897972	0.720095978907941
GO:0005165	neurotrophin receptor binding	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0005436	sodium:phosphate symporter activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0008179	adenylate cyclase binding	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0010853	cyclase activator activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0015132	prostaglandin transmembrane transporter activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0015269	calcium-activated potassium channel activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0016840	carbon-nitrogen lyase activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0035197	siRNA binding	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0035251	UDP-glucosyltransferase activity	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0045295	gamma-catenin binding	3/3305	12/18639	0.25	1.40990922844175	0.360591868592118	0.720095978907941
GO:0016298	lipase activity	25/3305	130/18639	0.192307692307692	1.08454556033981	0.361144823982712	0.720114076736613
GO:0019205	nucleobase-containing compound kinase activity	9/3305	44/18639	0.204545454545455	1.1535620959978	0.376475867328496	0.747866016851915
GO:0046875	ephrin receptor binding	6/3305	28/18639	0.214285714285714	1.20849362437865	0.376648716242588	0.747866016851915
GO:0005262	calcium channel activity	25/3305	131/18639	0.190839694656489	1.07626658659676	0.376757275861199	0.747866016851915
GO:0005283	amino acid:sodium symporter activity	5/3305	23/18639	0.217391304347826	1.22600802473196	0.387397565807561	0.762131318171191
GO:0016493	C-C chemokine receptor activity	5/3305	23/18639	0.217391304347826	1.22600802473196	0.387397565807561	0.762131318171191
GO:0016849	phosphorus-oxygen lyase activity	5/3305	23/18639	0.217391304347826	1.22600802473196	0.387397565807561	0.762131318171191
GO:0042171	lysophosphatidic acid acyltransferase activity	5/3305	23/18639	0.217391304347826	1.22600802473196	0.387397565807561	0.762131318171191
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	5/3305	23/18639	0.217391304347826	1.22600802473196	0.387397565807561	0.762131318171191
GO:0071617	lysophospholipid acyltransferase activity	5/3305	23/18639	0.217391304347826	1.22600802473196	0.387397565807561	0.762131318171191
GO:0015605	organophosphate ester transmembrane transporter activity	10/3305	50/18639	0.2	1.1279273827534	0.392621984564592	0.771263364337566
GO:0030332	cyclin binding	7/3305	34/18639	0.205882352941176	1.16110171754027	0.398257930840689	0.776400559158781
GO:0051427	hormone receptor binding	7/3305	34/18639	0.205882352941176	1.16110171754027	0.398257930840689	0.776400559158781
GO:0000900	mRNA regulatory element binding translation repressor activity	4/3305	18/18639	0.222222222222222	1.25325264750378	0.399341979446473	0.776400559158781
GO:0004706	JUN kinase kinase kinase activity	4/3305	18/18639	0.222222222222222	1.25325264750378	0.399341979446473	0.776400559158781
GO:0008308	voltage-gated monoatomic anion channel activity	4/3305	18/18639	0.222222222222222	1.25325264750378	0.399341979446473	0.776400559158781
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3305	18/18639	0.222222222222222	1.25325264750378	0.399341979446473	0.776400559158781
GO:1990381	ubiquitin-specific protease binding	4/3305	18/18639	0.222222222222222	1.25325264750378	0.399341979446473	0.776400559158781
GO:0003785	actin monomer binding	6/3305	29/18639	0.206896551724138	1.16682143043456	0.410975836154776	0.792219630461276
GO:0016417	S-acyltransferase activity	6/3305	29/18639	0.206896551724138	1.16682143043456	0.410975836154776	0.792219630461276
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0008253	5'-nucleotidase activity	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0019855	calcium channel inhibitor activity	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0030955	potassium ion binding	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0043560	insulin receptor substrate binding	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0046975	histone H3K36 methyltransferase activity	3/3305	13/18639	0.230769230769231	1.30145467240777	0.412863704696586	0.792219630461276
GO:0071949	FAD binding	8/3305	40/18639	0.2	1.1279273827534	0.41602199843686	0.797124639551958
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	24/3305	128/18639	0.1875	1.05743192133132	0.416719742544634	0.797307715504473
GO:0005048	signal sequence binding	10/3305	51/18639	0.196078431372549	1.10581115956216	0.418414245638136	0.799394604942125
GO:0004521	RNA endonuclease activity	14/3305	73/18639	0.191780821917808	1.08157420264025	0.419773062706264	0.799682784205889
GO:0043539	protein serine/threonine kinase activator activity	14/3305	73/18639	0.191780821917808	1.08157420264025	0.419773062706264	0.799682784205889
GO:0004622	lysophospholipase activity	5/3305	24/18639	0.208333333333333	1.1749243570348	0.425471773844752	0.80360146729023
GO:0004806	triacylglycerol lipase activity	5/3305	24/18639	0.208333333333333	1.1749243570348	0.425471773844752	0.80360146729023
GO:0005315	phosphate transmembrane transporter activity	5/3305	24/18639	0.208333333333333	1.1749243570348	0.425471773844752	0.80360146729023
GO:0005540	hyaluronic acid binding	5/3305	24/18639	0.208333333333333	1.1749243570348	0.425471773844752	0.80360146729023
GO:0015295	solute:proton symporter activity	5/3305	24/18639	0.208333333333333	1.1749243570348	0.425471773844752	0.80360146729023
GO:0070300	phosphatidic acid binding	5/3305	24/18639	0.208333333333333	1.1749243570348	0.425471773844752	0.80360146729023
GO:0015631	tubulin binding	70/3305	385/18639	0.181818181818182	1.02538852977582	0.428669083224357	0.807769033826476
GO:0016229	steroid dehydrogenase activity	7/3305	35/18639	0.2	1.1279273827534	0.42965230074871	0.807769033826476
GO:0043015	gamma-tubulin binding	7/3305	35/18639	0.2	1.1279273827534	0.42965230074871	0.807769033826476
GO:0015370	solute:sodium symporter activity	15/3305	79/18639	0.189873417721519	1.07081713552538	0.430118707588871	0.807769033826476
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0008301	DNA binding, bending	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0022840	leak channel activity	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0022842	narrow pore channel activity	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0031420	alkali metal ion binding	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0046527	glucosyltransferase activity	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0050145	nucleoside monophosphate kinase activity	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0120227	acyl-CoA binding	4/3305	19/18639	0.210526315789474	1.18729198184569	0.442533701493141	0.821759636433267
GO:0008187	poly-pyrimidine tract binding	6/3305	30/18639	0.2	1.1279273827534	0.445101515575091	0.824215953316673
GO:0022839	monoatomic ion-gated channel activity	6/3305	30/18639	0.2	1.1279273827534	0.445101515575091	0.824215953316673
GO:0002039	p53 binding	13/3305	69/18639	0.188405797101449	1.06254028810103	0.453275388953739	0.837548226826862
GO:0061980	regulatory RNA binding	11/3305	58/18639	0.189655172413793	1.06958631123168	0.455756495527538	0.837548226826862
GO:0050660	flavin adenine dinucleotide binding	16/3305	86/18639	0.186046511627907	1.04923477465433	0.459730930575808	0.837548226826862
GO:0000993	RNA polymerase II complex binding	7/3305	36/18639	0.194444444444444	1.09659606656581	0.460825199983257	0.837548226826862
GO:0016409	palmitoyltransferase activity	7/3305	36/18639	0.194444444444444	1.09659606656581	0.460825199983257	0.837548226826862
GO:0015271	outward rectifier potassium channel activity	5/3305	25/18639	0.2	1.1279273827534	0.463061233705481	0.837548226826862
GO:0015645	fatty acid ligase activity	5/3305	25/18639	0.2	1.1279273827534	0.463061233705481	0.837548226826862
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/3305	25/18639	0.2	1.1279273827534	0.463061233705481	0.837548226826862
GO:0019707	protein-cysteine S-acyltransferase activity	5/3305	25/18639	0.2	1.1279273827534	0.463061233705481	0.837548226826862
GO:0120515	fatty acid-CoA ligase activity	5/3305	25/18639	0.2	1.1279273827534	0.463061233705481	0.837548226826862
GO:0005313	L-glutamate transmembrane transporter activity	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0031404	chloride ion binding	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0032036	myosin heavy chain binding	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0043176	amine binding	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0070742	C2H2 zinc finger domain binding	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/3305	14/18639	0.214285714285714	1.20849362437865	0.463687953371669	0.837548226826862
GO:0017046	peptide hormone binding	10/3305	53/18639	0.188679245283019	1.06408243655981	0.46981821633869	0.847465011488318
GO:0035198	miRNA binding	8/3305	42/18639	0.19047619047619	1.07421655500324	0.473963484505923	0.852619094410111
GO:0043175	RNA polymerase core enzyme binding	8/3305	42/18639	0.19047619047619	1.07421655500324	0.473963484505923	0.852619094410111
GO:0070325	lipoprotein particle receptor binding	6/3305	31/18639	0.193548387096774	1.09154262847104	0.478792578088393	0.86013754869611
GO:0015459	potassium channel regulator activity	11/3305	59/18639	0.186440677966102	1.05145772968538	0.48005653812288	0.861239642919639
GO:0010851	cyclase regulator activity	4/3305	20/18639	0.2	1.1279273827534	0.484731022286057	0.865269605470021
GO:0015095	magnesium ion transmembrane transporter activity	4/3305	20/18639	0.2	1.1279273827534	0.484731022286057	0.865269605470021
GO:0052745	inositol phosphate phosphatase activity	4/3305	20/18639	0.2	1.1279273827534	0.484731022286057	0.865269605470021
GO:0140693	molecular condensate scaffold activity	9/3305	48/18639	0.1875	1.05743192133132	0.485272863151451	0.865269605470021
GO:0051082	unfolded protein binding	22/3305	121/18639	0.181818181818182	1.02538852977582	0.485570481015276	0.865269605470021
GO:0005112	Notch binding	5/3305	26/18639	0.192307692307692	1.08454556033981	0.499877160037633	0.884809304665543
GO:0008143	poly(A) binding	5/3305	26/18639	0.192307692307692	1.08454556033981	0.499877160037633	0.884809304665543
GO:0008198	ferrous iron binding	5/3305	26/18639	0.192307692307692	1.08454556033981	0.499877160037633	0.884809304665543
GO:0050750	low-density lipoprotein particle receptor binding	5/3305	26/18639	0.192307692307692	1.08454556033981	0.499877160037633	0.884809304665543
GO:0070006	metalloaminopeptidase activity	5/3305	26/18639	0.192307692307692	1.08454556033981	0.499877160037633	0.884809304665543
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	22/3305	122/18639	0.180327868852459	1.01698370576127	0.50243700764907	0.886994736808572
GO:0005245	voltage-gated calcium channel activity	8/3305	43/18639	0.186046511627907	1.04923477465433	0.502451701364373	0.886994736808572
GO:0070717	poly-purine tract binding	6/3305	32/18639	0.1875	1.05743192133132	0.511840958347711	0.889483018675836
GO:0120015	sterol transfer activity	6/3305	32/18639	0.1875	1.05743192133132	0.511840958347711	0.889483018675836
GO:0000287	magnesium ion binding	41/3305	230/18639	0.178260869565217	1.00532658028021	0.512302907588325	0.889483018675836
GO:0004129	cytochrome-c oxidase activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0008252	nucleotidase activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0034483	heparan sulfate sulfotransferase activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0048531	beta-1,3-galactosyltransferase activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0050780	dopamine receptor binding	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0061578	K63-linked deubiquitinase activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0140161	monocarboxylate:sodium symporter activity	3/3305	15/18639	0.2	1.1279273827534	0.512470590840466	0.889483018675836
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	15/3305	83/18639	0.180722891566265	1.01921149043982	0.512594821185546	0.889483018675836
GO:0003727	single-stranded RNA binding	16/3305	89/18639	0.179775280898876	1.01386731034014	0.519282355081465	0.899908165088822
GO:0042162	telomeric DNA binding	7/3305	38/18639	0.184210526315789	1.03888048411498	0.521820937713743	0.90194637275848
GO:0043531	ADP binding	7/3305	38/18639	0.184210526315789	1.03888048411498	0.521820937713743	0.90194637275848
GO:0004867	serine-type endopeptidase inhibitor activity	17/3305	95/18639	0.178947368421053	1.00919818456884	0.525555868737516	0.902541196153824
GO:0001846	opsonin binding	4/3305	21/18639	0.19047619047619	1.07421655500324	0.525573460902265	0.902541196153824
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/3305	21/18639	0.19047619047619	1.07421655500324	0.525573460902265	0.902541196153824
GO:0009975	cyclase activity	4/3305	21/18639	0.19047619047619	1.07421655500324	0.525573460902265	0.902541196153824
GO:0061891	calcium ion sensor activity	4/3305	21/18639	0.19047619047619	1.07421655500324	0.525573460902265	0.902541196153824
GO:0001046	core promoter sequence-specific DNA binding	8/3305	44/18639	0.181818181818182	1.02538852977582	0.530446331150123	0.907809513073704
GO:0030547	signaling receptor inhibitor activity	8/3305	44/18639	0.181818181818182	1.02538852977582	0.530446331150123	0.907809513073704
GO:0042054	histone methyltransferase activity	12/3305	67/18639	0.17910447761194	1.01008422336126	0.534828796088302	0.907809513073704
GO:0001671	ATPase activator activity	5/3305	27/18639	0.185185185185185	1.04437720625315	0.535672814292065	0.907809513073704
GO:0004364	glutathione transferase activity	5/3305	27/18639	0.185185185185185	1.04437720625315	0.535672814292065	0.907809513073704
GO:0016405	CoA-ligase activity	5/3305	27/18639	0.185185185185185	1.04437720625315	0.535672814292065	0.907809513073704
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/3305	27/18639	0.185185185185185	1.04437720625315	0.535672814292065	0.907809513073704
GO:0015085	calcium ion transmembrane transporter activity	26/3305	147/18639	0.17687074829932	0.997486801074439	0.539724257815749	0.907809513073704
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	23/3305	130/18639	0.176923076923077	0.997781915512627	0.540878792902515	0.907809513073704
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/3305	33/18639	0.181818181818182	1.02538852977582	0.544064887136575	0.907809513073704
GO:0003774	cytoskeletal motor activity	27/3305	153/18639	0.176470588235294	0.995230043605945	0.544364793720543	0.907809513073704
GO:0004252	serine-type endopeptidase activity	31/3305	176/18639	0.176136363636364	0.993345138220327	0.547597693495607	0.907809513073704
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/3305	39/18639	0.179487179487179	1.01224252298382	0.551344451239563	0.907809513073704
GO:0016776	phosphotransferase activity, phosphate group as acceptor	7/3305	39/18639	0.179487179487179	1.01224252298382	0.551344451239563	0.907809513073704
GO:0000182	rDNA binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0001094	TFIID-class transcription factor complex binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0004935	adrenergic receptor activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0005528	FK506 binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0008401	retinoic acid 4-hydroxylase activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0030957	Tat protein binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0031419	cobalamin binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0031434	mitogen-activated protein kinase kinase binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0045322	unmethylated CpG binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0050308	sugar-phosphatase activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0051378	serotonin binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0051864	histone H3K36 demethylase activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0051880	G-quadruplex DNA binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0099122	RNA polymerase II C-terminal domain binding	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0141109	transporter activator activity	2/3305	10/18639	0.2	1.1279273827534	0.551953669202667	0.907809513073704
GO:0000062	fatty-acyl-CoA binding	3/3305	16/18639	0.1875	1.05743192133132	0.558778553970975	0.914490488822708
GO:0015378	sodium:chloride symporter activity	3/3305	16/18639	0.1875	1.05743192133132	0.558778553970975	0.914490488822708
GO:0015562	efflux transmembrane transporter activity	3/3305	16/18639	0.1875	1.05743192133132	0.558778553970975	0.914490488822708
GO:0055102	lipase inhibitor activity	3/3305	16/18639	0.1875	1.05743192133132	0.558778553970975	0.914490488822708
GO:0031491	nucleosome binding	13/3305	74/18639	0.175675675675676	0.990747025391503	0.562525340684843	0.919485865514484
GO:0008093	cytoskeletal anchor activity	4/3305	22/18639	0.181818181818182	1.02538852977582	0.564774640996717	0.919755995915932
GO:0140517	protein-RNA adaptor activity	4/3305	22/18639	0.181818181818182	1.02538852977582	0.564774640996717	0.919755995915932
GO:0140784	metal ion sensor activity	4/3305	22/18639	0.181818181818182	1.02538852977582	0.564774640996717	0.919755995915932
GO:0004722	protein serine/threonine phosphatase activity	18/3305	103/18639	0.174757281553398	0.98556761599812	0.567722141033352	0.92342028836383
GO:0004601	peroxidase activity	10/3305	57/18639	0.175438596491228	0.989409984871407	0.569161949926966	0.924115165233862
GO:0008514	organic anion transmembrane transporter activity	47/3305	269/18639	0.174721189591078	0.98536407043513	0.569980237595279	0.924115165233862
GO:0005242	inward rectifier potassium channel activity	5/3305	28/18639	0.178571428571429	1.00707802031554	0.570243270389777	0.924115165233862
GO:0004620	phospholipase activity	19/3305	109/18639	0.174311926605505	0.983055975794251	0.572229675236001	0.925380775911476
GO:0016209	antioxidant activity	15/3305	86/18639	0.174418604651163	0.983657601238434	0.572422096277567	0.925380775911476
GO:0016831	carboxy-lyase activity	6/3305	34/18639	0.176470588235294	0.995230043605945	0.575309234914265	0.928913935398155
GO:0016279	protein-lysine N-methyltransferase activity	12/3305	69/18639	0.173913043478261	0.980806419785569	0.578957633943009	0.931445226191944
GO:0015291	secondary active transmembrane transporter activity	50/3305	287/18639	0.174216027874564	0.982515141771258	0.579584661458849	0.931445226191944
GO:0004540	RNA nuclease activity	21/3305	121/18639	0.173553719008264	0.978779960240557	0.580678379981351	0.931445226191944
GO:0033192	calmodulin-dependent protein phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0140791	histone H2AXS140 phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:1990439	MAP kinase serine/threonine phosphatase activity	14/3305	81/18639	0.172839506172839	0.974752059169608	0.587684521633775	0.931445226191944
GO:0016278	lysine N-methyltransferase activity	12/3305	70/18639	0.171428571428571	0.966794899502918	0.600349730836787	0.931445226191944
GO:0003887	DNA-directed DNA polymerase activity	4/3305	23/18639	0.173913043478261	0.980806419785569	0.602117183141802	0.931445226191944
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0004549	tRNA-specific ribonuclease activity	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0008569	minus-end-directed microtubule motor activity	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0016018	cyclosporin A binding	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0031489	myosin V binding	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0036041	long-chain fatty acid binding	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0045236	CXCR chemokine receptor binding	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0051787	misfolded protein binding	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:1901567	fatty acid derivative binding	3/3305	17/18639	0.176470588235294	0.995230043605945	0.602318220167001	0.931445226191944
GO:0005416	amino acid:monoatomic cation symporter activity	5/3305	29/18639	0.172413793103448	0.972351192028796	0.603423985855403	0.931445226191944
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0002162	dystroglycan binding	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0005536	D-glucose binding	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0008172	S-methyltransferase activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0010854	adenylate cyclase regulator activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0015173	aromatic amino acid transmembrane transporter activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0019107	myristoyltransferase activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0019203	carbohydrate phosphatase activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0019206	nucleoside kinase activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0032794	GTPase activating protein binding	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0034056	estrogen response element binding	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0070697	activin receptor binding	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0180030	inositol phosphate kinase activity	2/3305	11/18639	0.181818181818182	1.02538852977582	0.60624417738158	0.931445226191944
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/3305	82/18639	0.170731707317073	0.962864838935833	0.607349721920313	0.931445226191944
GO:0033549	MAP kinase phosphatase activity	14/3305	82/18639	0.170731707317073	0.962864838935833	0.607349721920313	0.931445226191944
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/3305	41/18639	0.170731707317073	0.962864838935833	0.607831325853353	0.931445226191944
GO:0140318	protein transporter activity	7/3305	41/18639	0.170731707317073	0.962864838935833	0.607831325853353	0.931445226191944
GO:0005200	structural constituent of cytoskeleton	19/3305	112/18639	0.169642857142857	0.956724119299762	0.622998239854335	0.953583433025595
GO:0045505	dynein intermediate chain binding	6/3305	36/18639	0.166666666666667	0.939939485627837	0.634369142796743	0.961184436262454
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/3305	36/18639	0.166666666666667	0.939939485627837	0.634369142796743	0.961184436262454
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/3305	36/18639	0.166666666666667	0.939939485627837	0.634369142796743	0.961184436262454
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/3305	36/18639	0.166666666666667	0.939939485627837	0.634369142796743	0.961184436262454
GO:0016859	cis-trans isomerase activity	7/3305	42/18639	0.166666666666667	0.939939485627837	0.634604894122839	0.961184436262454
GO:0031492	nucleosomal DNA binding	7/3305	42/18639	0.166666666666667	0.939939485627837	0.634604894122839	0.961184436262454
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/3305	30/18639	0.166666666666667	0.939939485627837	0.635088479911465	0.961184436262454
GO:0048019	receptor antagonist activity	5/3305	30/18639	0.166666666666667	0.939939485627837	0.635088479911465	0.961184436262454
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/3305	54/18639	0.166666666666667	0.939939485627837	0.636651875730097	0.961184436262454
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	39/3305	229/18639	0.170305676855895	0.960462181820584	0.637002745629159	0.961184436262454
GO:0030552	cAMP binding	4/3305	24/18639	0.166666666666667	0.939939485627837	0.637446265001212	0.961184436262454
GO:0050699	WW domain binding	4/3305	24/18639	0.166666666666667	0.939939485627837	0.637446265001212	0.961184436262454
GO:0140033	acetylation-dependent protein binding	4/3305	24/18639	0.166666666666667	0.939939485627837	0.637446265001212	0.961184436262454
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	10/3305	60/18639	0.166666666666667	0.939939485627837	0.638127733742218	0.961184436262454
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/3305	18/18639	0.166666666666667	0.939939485627837	0.642913468311107	0.964006151805102
GO:0008409	5'-3' exonuclease activity	3/3305	18/18639	0.166666666666667	0.939939485627837	0.642913468311107	0.964006151805102
GO:0015373	monoatomic anion:sodium symporter activity	3/3305	18/18639	0.166666666666667	0.939939485627837	0.642913468311107	0.964006151805102
GO:0031690	adrenergic receptor binding	3/3305	18/18639	0.166666666666667	0.939939485627837	0.642913468311107	0.964006151805102
GO:0017018	myosin phosphatase activity	14/3305	84/18639	0.166666666666667	0.939939485627837	0.645328456267553	0.966276194009645
GO:0005319	lipid transporter activity	30/3305	178/18639	0.168539325842697	0.95050060344388	0.651336461299802	0.966276194009645
GO:0004843	cysteine-type deubiquitinase activity	18/3305	108/18639	0.166666666666667	0.939939485627837	0.653242473019351	0.966276194009645
GO:0003995	acyl-CoA dehydrogenase activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0004126	cytidine deaminase activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0004859	phospholipase inhibitor activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0005049	nuclear export signal receptor activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0005527	macrolide binding	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0031543	peptidyl-proline dioxygenase activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0097371	MDM2/MDM4 family protein binding	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:1990459	transferrin receptor binding	2/3305	12/18639	0.166666666666667	0.939939485627837	0.655374639139472	0.966276194009645
GO:0008374	O-acyltransferase activity	9/3305	55/18639	0.163636363636364	0.92284967679824	0.659415220440666	0.971152115532193
GO:0022829	wide pore channel activity	6/3305	37/18639	0.162162162162162	0.914535715746003	0.662001694266773	0.97387804801023
GO:0016411	acylglycerol O-acyltransferase activity	5/3305	31/18639	0.161290322580645	0.909618857059197	0.66514538410821	0.976333135875022
GO:0016878	acid-thiol ligase activity	5/3305	31/18639	0.161290322580645	0.909618857059197	0.66514538410821	0.976333135875022
GO:0005537	D-mannose binding	4/3305	25/18639	0.16	0.902341906202723	0.670662461438495	0.983341194844482
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/3305	19/18639	0.157894736842105	0.890468986384266	0.680484674589476	0.99443897257888
GO:0034987	immunoglobulin receptor binding	3/3305	19/18639	0.157894736842105	0.890468986384266	0.680484674589476	0.99443897257888
GO:0042834	peptidoglycan binding	3/3305	19/18639	0.157894736842105	0.890468986384266	0.680484674589476	0.99443897257888
GO:0052689	carboxylic ester hydrolase activity	15/3305	92/18639	0.16304347826087	0.919506018548971	0.682025528789273	0.995438823962563
GO:0048020	CCR chemokine receptor binding	8/3305	50/18639	0.16	0.902341906202723	0.682672546947135	0.995438823962563
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	20/3305	122/18639	0.163934426229508	0.924530641601151	0.687174964916988	1
GO:0051087	protein-folding chaperone binding	22/3305	134/18639	0.164179104477612	0.925910538081153	0.689653418462431	1
GO:0015106	bicarbonate transmembrane transporter activity	5/3305	32/18639	0.15625	0.881193267776097	0.693535092582376	1
GO:0022884	macromolecule transmembrane transporter activity	5/3305	32/18639	0.15625	0.881193267776097	0.693535092582376	1
GO:0051059	NF-kappaB binding	5/3305	32/18639	0.15625	0.881193267776097	0.693535092582376	1
GO:0015081	sodium ion transmembrane transporter activity	27/3305	164/18639	0.164634146341463	0.928476808973839	0.696300742724824	1
GO:0004465	lipoprotein lipase activity	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0004535	poly(A)-specific ribonuclease activity	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0008417	fucosyltransferase activity	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0031432	titin binding	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0039706	co-receptor binding	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0046974	histone H3K9 methyltransferase activity	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:1901338	catecholamine binding	2/3305	13/18639	0.153846153846154	0.867636448271849	0.699467536310906	1
GO:0030507	spectrin binding	4/3305	26/18639	0.153846153846154	0.867636448271849	0.701714334420469	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	9/3305	57/18639	0.157894736842105	0.890468986384266	0.702360028004569	1
GO:0140303	intramembrane lipid transporter activity	7/3305	45/18639	0.155555555555556	0.877276853252647	0.708269502734994	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/3305	20/18639	0.15	0.845945537065053	0.715029436760667	1
GO:0030742	GTP-dependent protein binding	3/3305	20/18639	0.15	0.845945537065053	0.715029436760667	1
GO:0140939	histone H4 methyltransferase activity	3/3305	20/18639	0.15	0.845945537065053	0.715029436760667	1
GO:0008395	steroid hydroxylase activity	4/3305	27/18639	0.148148148148148	0.835501765002521	0.730591120529757	1
GO:0008509	monoatomic anion transmembrane transporter activity	24/3305	149/18639	0.161073825503356	0.908397892150392	0.73063427914448	1
GO:0005254	chloride channel activity	13/3305	83/18639	0.156626506024096	0.883316625047846	0.732280872343618	1
GO:0015144	carbohydrate transmembrane transporter activity	6/3305	40/18639	0.15	0.845945537065053	0.736678343749808	1
GO:0005344	oxygen carrier activity	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0005347	ATP transmembrane transporter activity	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0008494	translation activator activity	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0008559	ABC-type xenobiotic transporter activity	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0015386	potassium:proton antiporter activity	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0016530	metallochaperone activity	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0044548	S100 protein binding	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0098847	sequence-specific single stranded DNA binding	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:1901612	cardiolipin binding	2/3305	14/18639	0.142857142857143	0.805662416252431	0.738764133467446	1
GO:0019842	vitamin binding	24/3305	150/18639	0.16	0.902341906202723	0.74275558921675	1
GO:0046873	metal ion transmembrane transporter activity	75/3305	450/18639	0.166666666666667	0.939939485627837	0.743430757469213	1
GO:0019825	oxygen binding	5/3305	34/18639	0.147058823529412	0.829358369671621	0.745211884453461	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	5/3305	34/18639	0.147058823529412	0.829358369671621	0.745211884453461	1
GO:0090482	vitamin transmembrane transporter activity	5/3305	34/18639	0.147058823529412	0.829358369671621	0.745211884453461	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/3305	21/18639	0.142857142857143	0.805662416252431	0.746605432737067	1
GO:0015125	bile acid transmembrane transporter activity	3/3305	21/18639	0.142857142857143	0.805662416252431	0.746605432737067	1
GO:0140359	ABC-type transporter activity	7/3305	47/18639	0.148936170212766	0.839945923327003	0.751494330301336	1
GO:0022804	active transmembrane transporter activity	76/3305	457/18639	0.166301969365427	0.937882725265412	0.751561732168343	1
GO:0019783	ubiquitin-like protein peptidase activity	20/3305	127/18639	0.15748031496063	0.888131797443625	0.75523695960846	1
GO:0015108	chloride transmembrane transporter activity	19/3305	121/18639	0.15702479338843	0.885562821170028	0.755740148668623	1
GO:0101005	deubiquitinase activity	18/3305	115/18639	0.156521739130435	0.882725777807012	0.756413381519786	1
GO:0008017	microtubule binding	45/3305	276/18639	0.16304347826087	0.919506018548971	0.756917367772095	1
GO:0051119	sugar transmembrane transporter activity	4/3305	28/18639	0.142857142857143	0.805662416252431	0.757315762219754	1
GO:0005253	monoatomic anion channel activity	16/3305	103/18639	0.155339805825243	0.87606010310944	0.758381077005138	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/3305	41/18639	0.146341463414634	0.825312719087857	0.758766403960629	1
GO:0017080	sodium channel regulator activity	6/3305	41/18639	0.146341463414634	0.825312719087857	0.758766403960629	1
GO:0046943	carboxylic acid transmembrane transporter activity	30/3305	188/18639	0.159574468085106	0.899942060707503	0.766302084763905	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	7/3305	48/18639	0.145833333333333	0.822447049924357	0.771309326686205	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	10/3305	67/18639	0.149253731343284	0.841736852801048	0.772754113422408	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0016846	carbon-sulfur lyase activity	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0030553	cGMP binding	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0031386	protein tag activity	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0033130	acetylcholine receptor binding	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0050700	CARD domain binding	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0140776	protein-containing complex destabilizing activity	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0141047	molecular tag activity	2/3305	15/18639	0.133333333333333	0.751951588502269	0.773578524640827	1
GO:0008170	N-methyltransferase activity	15/3305	98/18639	0.153061224489796	0.863209731699034	0.77363795993276	1
GO:0042626	ATPase-coupled transmembrane transporter activity	15/3305	98/18639	0.153061224489796	0.863209731699034	0.77363795993276	1
GO:0008970	phospholipase A1 activity	3/3305	22/18639	0.136363636363636	0.769041397331866	0.775315557748702	1
GO:0005342	organic acid transmembrane transporter activity	30/3305	189/18639	0.158730158730159	0.895180462502701	0.776309529023927	1
GO:0004520	DNA endonuclease activity	6/3305	42/18639	0.142857142857143	0.805662416252431	0.779459988933594	1
GO:0008307	structural constituent of muscle	6/3305	42/18639	0.142857142857143	0.805662416252431	0.779459988933594	1
GO:0051879	Hsp90 protein binding	6/3305	42/18639	0.142857142857143	0.805662416252431	0.779459988933594	1
GO:0106222	lncRNA binding	4/3305	29/18639	0.137931034482759	0.777880953623037	0.78193844643805	1
GO:0003684	damaged DNA binding	11/3305	74/18639	0.148648648648649	0.838324406100503	0.784508445385719	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	10/3305	68/18639	0.147058823529412	0.829358369671621	0.788689265726752	1
GO:0035254	glutamate receptor binding	7/3305	49/18639	0.142857142857143	0.805662416252431	0.789937740724567	1
GO:0004033	aldo-keto reductase (NADPH) activity	5/3305	36/18639	0.138888888888889	0.783282904689864	0.7901413715837	1
GO:0043022	ribosome binding	17/3305	112/18639	0.151785714285714	0.856016317268208	0.79549843472928	1
GO:0030170	pyridoxal phosphate binding	8/3305	56/18639	0.142857142857143	0.805662416252431	0.799868088992752	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/3305	23/18639	0.130434782608696	0.735604814839176	0.801295313939736	1
GO:0031681	G-protein beta-subunit binding	3/3305	23/18639	0.130434782608696	0.735604814839176	0.801295313939736	1
GO:0070577	lysine-acetylated histone binding	3/3305	23/18639	0.130434782608696	0.735604814839176	0.801295313939736	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0008296	3'-5'-DNA exonuclease activity	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0015385	sodium:proton antiporter activity	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0043023	ribosomal large subunit binding	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0097027	ubiquitin-protein transferase activator activity	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0140327	flippase activity	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0140328	floppase activity	2/3305	16/18639	0.125	0.704954614220877	0.80426423473652	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/3305	30/18639	0.133333333333333	0.751951588502269	0.804530748980601	1
GO:0031210	phosphatidylcholine binding	4/3305	30/18639	0.133333333333333	0.751951588502269	0.804530748980601	1
GO:0070566	adenylyltransferase activity	4/3305	30/18639	0.133333333333333	0.751951588502269	0.804530748980601	1
GO:1901682	sulfur compound transmembrane transporter activity	9/3305	63/18639	0.142857142857143	0.805662416252431	0.809244661683138	1
GO:0030551	cyclic nucleotide binding	5/3305	37/18639	0.135135135135135	0.762113096455003	0.810163196164469	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	20/3305	132/18639	0.151515151515152	0.854490441479851	0.812902179985765	1
GO:0008276	protein methyltransferase activity	14/3305	95/18639	0.147368421052632	0.831104387291982	0.81484386577922	1
GO:0022832	voltage-gated channel activity	27/3305	175/18639	0.154285714285714	0.870115409552626	0.815192732253063	1
GO:0070279	vitamin B6 binding	8/3305	57/18639	0.140350877192982	0.791527987897126	0.815787772419395	1
GO:0016790	thiolester hydrolase activity	6/3305	44/18639	0.136363636363636	0.769041397331866	0.8167695114395	1
GO:0016597	amino acid binding	7/3305	51/18639	0.137254901960784	0.774067811693513	0.823721975773477	1
GO:0016830	carbon-carbon lyase activity	7/3305	51/18639	0.137254901960784	0.774067811693513	0.823721975773477	1
GO:0030544	Hsp70 protein binding	7/3305	51/18639	0.137254901960784	0.774067811693513	0.823721975773477	1
GO:0004536	DNA nuclease activity	9/3305	64/18639	0.140625	0.793073940998487	0.823858551030506	1
GO:0048027	mRNA 5'-UTR binding	3/3305	24/18639	0.125	0.704954614220877	0.824702320930954	1
GO:0070840	dynein complex binding	3/3305	24/18639	0.125	0.704954614220877	0.824702320930954	1
GO:0004519	endonuclease activity	19/3305	127/18639	0.149606299212598	0.843725207571444	0.824970166419911	1
GO:0047499	calcium-independent phospholipase A2 activity	4/3305	31/18639	0.129032258064516	0.727695085647357	0.8251804326654	1
GO:0046906	tetrapyrrole binding	23/3305	152/18639	0.151315789473684	0.853366111951589	0.828338302389807	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/3305	17/18639	0.117647058823529	0.663486695737296	0.831190370012456	1
GO:0030548	acetylcholine receptor regulator activity	2/3305	17/18639	0.117647058823529	0.663486695737296	0.831190370012456	1
GO:0032977	membrane insertase activity	2/3305	17/18639	0.117647058823529	0.663486695737296	0.831190370012456	1
GO:0070492	oligosaccharide binding	2/3305	17/18639	0.117647058823529	0.663486695737296	0.831190370012456	1
GO:0015103	inorganic anion transmembrane transporter activity	25/3305	165/18639	0.151515151515152	0.854490441479851	0.834828465918517	1
GO:0061775	cohesin loader activity	23/3305	153/18639	0.150326797385621	0.847788555664323	0.837415486111411	1
GO:0120013	lipid transfer activity	9/3305	65/18639	0.138461538461538	0.780872803444664	0.837596562356847	1
GO:0160215	deacylase activity	9/3305	65/18639	0.138461538461538	0.780872803444664	0.837596562356847	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/3305	52/18639	0.134615384615385	0.759181892237868	0.838938591692171	1
GO:0015399	primary active transmembrane transporter activity	25/3305	166/18639	0.150602409638554	0.849342908699852	0.843339044760679	1
GO:0042910	xenobiotic transmembrane transporter activity	4/3305	32/18639	0.125	0.704954614220877	0.843986909820118	1
GO:0140142	nucleocytoplasmic carrier activity	4/3305	32/18639	0.125	0.704954614220877	0.843986909820118	1
GO:0004518	nuclease activity	32/3305	209/18639	0.15311004784689	0.863485077705955	0.84460033017769	1
GO:0000217	DNA secondary structure binding	5/3305	39/18639	0.128205128205128	0.723030373559874	0.845606784015997	1
GO:0015662	P-type ion transporter activity	3/3305	25/18639	0.12	0.676756429652042	0.84570775631629	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/3305	25/18639	0.12	0.676756429652042	0.84570775631629	1
GO:0017056	structural constituent of nuclear pore	3/3305	25/18639	0.12	0.676756429652042	0.84570775631629	1
GO:0140358	P-type transmembrane transporter activity	3/3305	25/18639	0.12	0.676756429652042	0.84570775631629	1
GO:0020037	heme binding	21/3305	142/18639	0.147887323943662	0.834030811190897	0.849538593029888	1
GO:0005244	voltage-gated monoatomic ion channel activity	26/3305	173/18639	0.15028901734104	0.847575489930304	0.850227371920799	1
GO:0099094	ligand-gated monoatomic cation channel activity	20/3305	136/18639	0.147058823529412	0.829358369671621	0.85150831723059	1
GO:0004864	protein phosphatase inhibitor activity	7/3305	53/18639	0.132075471698113	0.74485770559187	0.853087840139083	1
GO:0000400	four-way junction DNA binding	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0008525	phosphatidylcholine transporter activity	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0017128	phospholipid scramblase activity	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0099602	neurotransmitter receptor regulator activity	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:1901611	phosphatidylglycerol binding	2/3305	18/18639	0.111111111111111	0.626626323751891	0.854724982725125	1
GO:0003796	lysozyme activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0004983	neuropeptide Y receptor activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0005337	nucleoside transmembrane transporter activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0008190	eukaryotic initiation factor 4E binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0015187	glycine transmembrane transporter activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0015203	polyamine transmembrane transporter activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0016783	sulfurtransferase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0016868	intramolecular phosphotransferase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0031720	haptoglobin binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0031996	thioesterase binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0032052	bile acid binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0033204	ribonuclease P RNA binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0043121	neurotrophin binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0043295	glutathione binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0050815	phosphoserine residue binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0070739	protein-glutamic acid ligase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0098505	G-rich strand telomeric DNA binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0140940	histone H2A methyltransferase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:1990757	ubiquitin ligase activator activity	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:1990763	arrestin family protein binding	1/3305	10/18639	0.1	0.563963691376702	0.858060774791336	1
GO:0022853	active monoatomic ion transmembrane transporter activity	17/3305	118/18639	0.144067796610169	0.812490063847791	0.858738319522862	1
GO:0004532	RNA exonuclease activity	5/3305	40/18639	0.125	0.704954614220877	0.86116798976831	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	5/3305	40/18639	0.125	0.704954614220877	0.86116798976831	1
GO:0050997	quaternary ammonium group binding	5/3305	40/18639	0.125	0.704954614220877	0.86116798976831	1
GO:0031072	heat shock protein binding	19/3305	131/18639	0.145038167938931	0.817962605813537	0.862413620309647	1
GO:0061749	forked DNA-dependent helicase activity	6/3305	47/18639	0.127659574468085	0.719953648566003	0.863164658518213	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/3305	47/18639	0.127659574468085	0.719953648566003	0.863164658518213	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	27/3305	181/18639	0.149171270718232	0.841271804816075	0.864148638391927	1
GO:0004529	DNA exonuclease activity	3/3305	26/18639	0.115384615384615	0.650727336203887	0.864489506998353	1
GO:0015145	monosaccharide transmembrane transporter activity	3/3305	26/18639	0.115384615384615	0.650727336203887	0.864489506998353	1
GO:0051139	metal cation:proton antiporter activity	3/3305	26/18639	0.115384615384615	0.650727336203887	0.864489506998353	1
GO:0005548	phospholipid transporter activity	9/3305	68/18639	0.132352941176471	0.746422532704458	0.873810040208809	1
GO:0008574	plus-end-directed microtubule motor activity	2/3305	19/18639	0.105263157894737	0.593645990922844	0.875223842505789	1
GO:0022821	solute:potassium antiporter activity	2/3305	19/18639	0.105263157894737	0.593645990922844	0.875223842505789	1
GO:0030506	ankyrin binding	2/3305	19/18639	0.105263157894737	0.593645990922844	0.875223842505789	1
GO:0046624	sphingolipid transporter activity	2/3305	19/18639	0.105263157894737	0.593645990922844	0.875223842505789	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3305	41/18639	0.121951219512195	0.68776059923988	0.875390432241599	1
GO:0009378	four-way junction helicase activity	6/3305	48/18639	0.125	0.704954614220877	0.876286848779929	1
GO:0036121	double-stranded DNA helicase activity	6/3305	48/18639	0.125	0.704954614220877	0.876286848779929	1
GO:0043138	3'-5' DNA helicase activity	6/3305	48/18639	0.125	0.704954614220877	0.876286848779929	1
GO:0015020	glucuronosyltransferase activity	4/3305	34/18639	0.117647058823529	0.663486695737296	0.876503414858258	1
GO:0140658	ATP-dependent chromatin remodeler activity	23/3305	158/18639	0.145569620253165	0.820959803902794	0.877542054164056	1
GO:0044183	protein folding chaperone	10/3305	75/18639	0.133333333333333	0.751951588502269	0.877926280283382	1
GO:0043021	ribonucleoprotein complex binding	26/3305	177/18639	0.146892655367232	0.828421241570297	0.879516017381813	1
GO:0008320	protein transmembrane transporter activity	3/3305	27/18639	0.111111111111111	0.626626323751891	0.881226805306928	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/3305	27/18639	0.111111111111111	0.626626323751891	0.881226805306928	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/3305	27/18639	0.111111111111111	0.626626323751891	0.881226805306928	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0008199	ferric iron binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0008503	benzodiazepine receptor activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0015217	ADP transmembrane transporter activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0031731	CCR6 chemokine receptor binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0032404	mismatch repair complex binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0035252	UDP-xylosyltransferase activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0042285	xylosyltransferase activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0043522	leucine zipper domain binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0070990	snRNP binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:1900750	oligopeptide binding	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:1990948	ubiquitin ligase inhibitor activity	1/3305	11/18639	0.0909090909090909	0.512694264887911	0.883242434532312	1
GO:0003697	single-stranded DNA binding	17/3305	121/18639	0.140495867768595	0.792345682099499	0.884123144514113	1
GO:0015171	amino acid transmembrane transporter activity	14/3305	102/18639	0.137254901960784	0.774067811693513	0.886256704815263	1
GO:0060590	ATPase regulator activity	6/3305	49/18639	0.122448979591837	0.690567785359227	0.88833556153184	1
GO:0019212	phosphatase inhibitor activity	7/3305	56/18639	0.125	0.704954614220877	0.889569567803332	1
GO:0004623	phospholipase A2 activity	4/3305	35/18639	0.114285714285714	0.644529933001945	0.89043852131639	1
GO:0034061	DNA polymerase activity	4/3305	35/18639	0.114285714285714	0.644529933001945	0.89043852131639	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/3305	20/18639	0.1	0.563963691376702	0.893023220921914	1
GO:0061608	nuclear import signal receptor activity	2/3305	20/18639	0.1	0.563963691376702	0.893023220921914	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/3305	28/18639	0.107142857142857	0.604246812189324	0.896096130477389	1
GO:0004527	exonuclease activity	11/3305	84/18639	0.130952380952381	0.738523881564729	0.899863908274579	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/3305	43/18639	0.116279069767442	0.655771734158956	0.90013966275604	1
GO:0016779	nucleotidyltransferase activity	19/3305	136/18639	0.139705882352941	0.78789045118804	0.900169410826625	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	4/3305	36/18639	0.111111111111111	0.626626323751891	0.902975665032976	1
GO:0140299	molecular sensor activity	9/3305	71/18639	0.126760563380282	0.714883552449341	0.903156425324146	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0004526	ribonuclease P activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0015166	polyol transmembrane transporter activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0016273	arginine N-methyltransferase activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0016274	protein-arginine N-methyltransferase activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0016801	hydrolase activity, acting on ether bonds	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0016803	ether hydrolase activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0043047	single-stranded telomeric DNA binding	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3305	12/18639	0.0833333333333333	0.469969742813918	0.903957688658933	1
GO:0022843	voltage-gated monoatomic cation channel activity	20/3305	143/18639	0.13986013986014	0.788760407519863	0.904124477723942	1
GO:0005248	voltage-gated sodium channel activity	2/3305	21/18639	0.0952380952380952	0.537108277501621	0.908435619678214	1
GO:0015174	basic amino acid transmembrane transporter activity	2/3305	21/18639	0.0952380952380952	0.537108277501621	0.908435619678214	1
GO:0051428	peptide hormone receptor binding	2/3305	21/18639	0.0952380952380952	0.537108277501621	0.908435619678214	1
GO:0017116	single-stranded DNA helicase activity	7/3305	58/18639	0.120689655172414	0.680645834420158	0.909394708709034	1
GO:0003743	translation initiation factor activity	6/3305	51/18639	0.117647058823529	0.663486695737296	0.909459004175012	1
GO:0005272	sodium channel activity	6/3305	51/18639	0.117647058823529	0.663486695737296	0.909459004175012	1
GO:0000510	H3-H4 histone complex chaperone activity	21/3305	151/18639	0.139072847682119	0.784320365490778	0.913704675037654	1
GO:0140584	chromatin extrusion motor activity	21/3305	151/18639	0.139072847682119	0.784320365490778	0.913704675037654	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	21/3305	151/18639	0.139072847682119	0.784320365490778	0.913704675037654	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	21/3305	151/18639	0.139072847682119	0.784320365490778	0.913704675037654	1
GO:0005179	hormone activity	18/3305	132/18639	0.136363636363636	0.769041397331866	0.915375376092775	1
GO:0015616	DNA translocase activity	21/3305	152/18639	0.138157894736842	0.779160363086233	0.91919538481198	1
GO:0140674	ATP-dependent histone chaperone activity	21/3305	152/18639	0.138157894736842	0.779160363086233	0.91919538481198	1
GO:0051539	4 iron, 4 sulfur cluster binding	5/3305	45/18639	0.111111111111111	0.626626323751891	0.920498934096945	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0019104	DNA N-glycosylase activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0051011	microtubule minus-end binding	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0061459	L-arginine transmembrane transporter activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0071837	HMG box domain binding	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0089720	caspase binding	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0097157	pre-mRNA intronic binding	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0140333	glycerophospholipid flippase activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0140666	annealing activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0140852	histone ubiquitin ligase activity	1/3305	13/18639	0.0769230769230769	0.433818224135925	0.920998534687936	1
GO:0034062	5'-3' RNA polymerase activity	2/3305	22/18639	0.0909090909090909	0.512694264887911	0.921747625871165	1
GO:0070034	telomerase RNA binding	2/3305	22/18639	0.0909090909090909	0.512694264887911	0.921747625871165	1
GO:0097747	RNA polymerase activity	2/3305	22/18639	0.0909090909090909	0.512694264887911	0.921747625871165	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	4/3305	38/18639	0.105263157894737	0.593645990922844	0.924295797793917	1
GO:0005544	calcium-dependent phospholipid binding	6/3305	53/18639	0.113207547169811	0.638449461935889	0.927027890596595	1
GO:0016860	intramolecular oxidoreductase activity	6/3305	53/18639	0.113207547169811	0.638449461935889	0.927027890596595	1
GO:0015079	potassium ion transmembrane transporter activity	22/3305	160/18639	0.1375	0.775450075642965	0.927197577810582	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	11/3305	88/18639	0.125	0.704954614220877	0.928769912395578	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	5/3305	46/18639	0.108695652173913	0.61300401236598	0.929229429482263	1
GO:0005506	iron ion binding	21/3305	154/18639	0.136363636363636	0.769041397331866	0.929313671088654	1
GO:0005452	solute:inorganic anion antiporter activity	3/3305	31/18639	0.0967741935483871	0.545771314235518	0.931161936873453	1
GO:0015297	antiporter activity	18/3305	135/18639	0.133333333333333	0.751951588502269	0.931641523256533	1
GO:0003777	microtubule motor activity	8/3305	68/18639	0.117647058823529	0.663486695737296	0.932964718562468	1
GO:0008171	O-methyltransferase activity	2/3305	23/18639	0.0869565217391304	0.490403209892784	0.933219274626539	1
GO:0099186	structural constituent of postsynapse	2/3305	23/18639	0.0869565217391304	0.490403209892784	0.933219274626539	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	7/3305	61/18639	0.114754098360656	0.647171449120806	0.933371801122429	1
GO:0004386	helicase activity	21/3305	155/18639	0.135483870967742	0.764079839929725	0.933962324796582	1
GO:0008195	phosphatidate phosphatase activity	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0008474	palmitoyl-(protein) hydrolase activity	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0015926	glucosidase activity	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0019992	diacylglycerol binding	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0030983	mismatched DNA binding	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0061783	peptidoglycan muralytic activity	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0098599	palmitoyl hydrolase activity	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:1901474	azole transmembrane transporter activity	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:1990825	sequence-specific mRNA binding	1/3305	14/18639	0.0714285714285714	0.402831208126216	0.93501656555105	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/3305	47/18639	0.106382978723404	0.599961373805002	0.93709428316846	1
GO:0031369	translation initiation factor binding	3/3305	32/18639	0.09375	0.528715960665658	0.940180043120349	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/3305	32/18639	0.09375	0.528715960665658	0.940180043120349	1
GO:0015036	disulfide oxidoreductase activity	4/3305	40/18639	0.1	0.563963691376702	0.941302254403482	1
GO:0071855	neuropeptide receptor binding	4/3305	40/18639	0.1	0.563963691376702	0.941302254403482	1
GO:0140662	ATP-dependent protein folding chaperone	4/3305	40/18639	0.1	0.563963691376702	0.941302254403482	1
GO:0005267	potassium channel activity	16/3305	124/18639	0.129032258064516	0.727695085647357	0.941923906027268	1
GO:0015149	hexose transmembrane transporter activity	2/3305	24/18639	0.0833333333333333	0.469969742813918	0.943084452235229	1
GO:0055056	D-glucose transmembrane transporter activity	2/3305	24/18639	0.0833333333333333	0.469969742813918	0.943084452235229	1
GO:0140612	DNA damage sensor activity	2/3305	24/18639	0.0833333333333333	0.469969742813918	0.943084452235229	1
GO:0005249	voltage-gated potassium channel activity	12/3305	98/18639	0.122448979591837	0.690567785359227	0.94616217779725	1
GO:0000774	adenyl-nucleotide exchange factor activity	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0010181	FMN binding	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0015250	water channel activity	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0045504	dynein heavy chain binding	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/3305	15/18639	0.0666666666666667	0.375975794251135	0.946547854187495	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/3305	41/18639	0.0975609756097561	0.550208479391904	0.948427856799361	1
GO:0008227	G protein-coupled amine receptor activity	4/3305	41/18639	0.0975609756097561	0.550208479391904	0.948427856799361	1
GO:0000030	mannosyltransferase activity	2/3305	25/18639	0.08	0.451170953101362	0.951551991010789	1
GO:0005251	delayed rectifier potassium channel activity	2/3305	25/18639	0.08	0.451170953101362	0.951551991010789	1
GO:0003689	DNA clamp loader activity	21/3305	160/18639	0.13125	0.740202344931921	0.953520753429301	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/3305	34/18639	0.0882352941176471	0.497615021802972	0.955020269992585	1
GO:0030275	LRR domain binding	1/3305	16/18639	0.0625	0.352477307110439	0.95603342881756	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/3305	16/18639	0.0625	0.352477307110439	0.95603342881756	1
GO:0003823	antigen binding	23/3305	174/18639	0.132183908045977	0.745469247222077	0.956359983356003	1
GO:0120014	phospholipid transfer activity	2/3305	26/18639	0.0769230769230769	0.433818224135925	0.958807198011825	1
GO:0000175	3'-5'-RNA exonuclease activity	3/3305	35/18639	0.0857142857142857	0.483397449751459	0.961074808930978	1
GO:0004659	prenyltransferase activity	1/3305	17/18639	0.0588235294117647	0.331743347868648	0.963836119992879	1
GO:0009881	photoreceptor activity	1/3305	17/18639	0.0588235294117647	0.331743347868648	0.963836119992879	1
GO:0032183	SUMO binding	1/3305	17/18639	0.0588235294117647	0.331743347868648	0.963836119992879	1
GO:0048038	quinone binding	1/3305	17/18639	0.0588235294117647	0.331743347868648	0.963836119992879	1
GO:0003678	DNA helicase activity	8/3305	74/18639	0.108108108108108	0.609690477164002	0.963863559906792	1
GO:0035255	ionotropic glutamate receptor binding	2/3305	27/18639	0.0740740740740741	0.417750882501261	0.965013629428217	1
GO:0046982	protein heterodimerization activity	53/3305	369/18639	0.143631436314363	0.810029150215859	0.965211617562182	1
GO:0003954	NADH dehydrogenase activity	4/3305	44/18639	0.0909090909090909	0.512694264887911	0.965305074182299	1
GO:0140713	histone chaperone activity	21/3305	164/18639	0.128048780487805	0.722148629201875	0.965355847857822	1
GO:0055106	ubiquitin-protein transferase regulator activity	3/3305	36/18639	0.0833333333333333	0.469969742813918	0.966356549285342	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/3305	60/18639	0.1	0.563963691376702	0.967133888167347	1
GO:0015078	proton transmembrane transporter activity	24/3305	185/18639	0.12972972972973	0.731628572596803	0.968129496926867	1
GO:0003746	translation elongation factor activity	1/3305	18/18639	0.0555555555555556	0.313313161875946	0.970254422185099	1
GO:0005372	water transmembrane transporter activity	1/3305	18/18639	0.0555555555555556	0.313313161875946	0.970254422185099	1
GO:0015280	ligand-gated sodium channel activity	1/3305	18/18639	0.0555555555555556	0.313313161875946	0.970254422185099	1
GO:0070628	proteasome binding	1/3305	18/18639	0.0555555555555556	0.313313161875946	0.970254422185099	1
GO:0180051	translation factor activity	9/3305	84/18639	0.107142857142857	0.604246812189324	0.972875316174597	1
GO:0003724	RNA helicase activity	8/3305	77/18639	0.103896103896104	0.585936302729041	0.973865115925673	1
GO:0022834	ligand-gated channel activity	24/3305	188/18639	0.127659574468085	0.719953648566003	0.974376638394055	1
GO:0140597	protein carrier chaperone	24/3305	188/18639	0.127659574468085	0.719953648566003	0.974376638394055	1
GO:0003756	protein disulfide isomerase activity	1/3305	19/18639	0.0526315789473684	0.296822995461422	0.97553389883395	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/3305	19/18639	0.0526315789473684	0.296822995461422	0.97553389883395	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/3305	19/18639	0.0526315789473684	0.296822995461422	0.97553389883395	1
GO:0042577	lipid phosphatase activity	1/3305	19/18639	0.0526315789473684	0.296822995461422	0.97553389883395	1
GO:0099589	serotonin receptor activity	1/3305	19/18639	0.0526315789473684	0.296822995461422	0.97553389883395	1
GO:0098918	structural constituent of synapse	2/3305	30/18639	0.0666666666666667	0.375975794251135	0.978689196649271	1
GO:0008186	ATP-dependent activity, acting on RNA	8/3305	79/18639	0.10126582278481	0.571102472280204	0.979050677653126	1
GO:0015464	acetylcholine receptor activity	1/3305	20/18639	0.05	0.281981845688351	0.979876566092478	1
GO:0016408	C-acyltransferase activity	1/3305	20/18639	0.05	0.281981845688351	0.979876566092478	1
GO:0009055	electron transfer activity	13/3305	116/18639	0.112068965517241	0.632028274818718	0.980392602629449	1
GO:0005184	neuropeptide hormone activity	2/3305	31/18639	0.0645161290322581	0.363847542823679	0.981966938702775	1
GO:0072349	modified amino acid transmembrane transporter activity	2/3305	31/18639	0.0645161290322581	0.363847542823679	0.981966938702775	1
GO:0015276	ligand-gated monoatomic ion channel activity	23/3305	186/18639	0.123655913978495	0.697374457078717	0.982041633238644	1
GO:0019843	rRNA binding	6/3305	65/18639	0.0923076923076923	0.52058186896311	0.982057108809842	1
GO:0016853	isomerase activity	22/3305	180/18639	0.122222222222222	0.68928895612708	0.983089855822104	1
GO:1904047	S-adenosyl-L-methionine binding	1/3305	21/18639	0.0476190476190476	0.26855413875081	0.983448613413191	1
GO:0008408	3'-5' exonuclease activity	5/3305	58/18639	0.0862068965517241	0.486175596014398	0.984183197599401	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	5/3305	58/18639	0.0862068965517241	0.486175596014398	0.984183197599401	1
GO:0160041	neuropeptide activity	2/3305	32/18639	0.0625	0.352477307110439	0.984752731741604	1
GO:0140104	molecular carrier activity	32/3305	249/18639	0.1285140562249	0.724772615423874	0.985548371443597	1
GO:0016881	acid-amino acid ligase activity	1/3305	22/18639	0.0454545454545455	0.256347132443955	0.986386755677098	1
GO:0008094	ATP-dependent activity, acting on DNA	26/3305	210/18639	0.123809523809524	0.698240760752107	0.986579017444814	1
GO:0008135	translation factor activity, RNA binding	8/3305	83/18639	0.0963855421686747	0.543579461567905	0.986694195242538	1
GO:0042923	neuropeptide binding	2/3305	33/18639	0.0606060606060606	0.341796176591941	0.98711792009999	1
GO:0004497	monooxygenase activity	11/3305	106/18639	0.10377358490566	0.585245340107898	0.987417032437591	1
GO:0051536	iron-sulfur cluster binding	7/3305	76/18639	0.0921052631578947	0.519440242057489	0.987804262519532	1
GO:0016917	GABA receptor activity	1/3305	23/18639	0.0434782608695652	0.245201604946392	0.988803459361214	1
GO:0140102	catalytic activity, acting on a rRNA	1/3305	23/18639	0.0434782608695652	0.245201604946392	0.988803459361214	1
GO:0015035	protein-disulfide reductase activity	2/3305	34/18639	0.0588235294117647	0.331743347868648	0.989124023231703	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/3305	34/18639	0.0588235294117647	0.331743347868648	0.989124023231703	1
GO:0051540	metal cluster binding	7/3305	77/18639	0.0909090909090909	0.512694264887911	0.989198177178918	1
GO:0016836	hydro-lyase activity	5/3305	61/18639	0.0819672131147541	0.462265320800575	0.989392530606201	1
GO:0016887	ATP hydrolysis activity	57/3305	417/18639	0.136690647482014	0.770885621306283	0.989940256983211	1
GO:0005261	monoatomic cation channel activity	45/3305	341/18639	0.131964809384164	0.744233610321161	0.990790221508392	1
GO:0140097	catalytic activity, acting on DNA	44/3305	336/18639	0.130952380952381	0.738523881564729	0.991655268523038	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/3305	46/18639	0.0652173913043478	0.367802407419588	0.992612670994571	1
GO:0016829	lyase activity	23/3305	200/18639	0.115	0.648558245083207	0.994288698249041	1
GO:0015252	proton channel activity	1/3305	27/18639	0.037037037037037	0.20887544125063	0.99487702322764	1
GO:0008528	G protein-coupled peptide receptor activity	12/3305	122/18639	0.0983606557377049	0.55471838496069	0.994922574604695	1
GO:0022836	gated channel activity	40/3305	318/18639	0.125786163522013	0.709388291039877	0.99528770925684	1
GO:0008527	taste receptor activity	1/3305	28/18639	0.0357142857142857	0.201415604063108	0.995786728698984	1
GO:0016866	intramolecular transferase activity	1/3305	28/18639	0.0357142857142857	0.201415604063108	0.995786728698984	1
GO:0036002	pre-mRNA binding	4/3305	59/18639	0.0677966101694915	0.382348265340137	0.995868187617932	1
GO:0005216	monoatomic ion channel activity	59/3305	448/18639	0.131696428571429	0.74272003998271	0.996621963646635	1
GO:0001653	peptide receptor activity	12/3305	128/18639	0.09375	0.528715960665658	0.997371996235684	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/3305	53/18639	0.0566037735849057	0.319224730967945	0.997566256020539	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/3305	31/18639	0.032258064516129	0.181923771411839	0.997656417173271	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	17/3305	167/18639	0.101796407185629	0.57409477565293	0.997737222610098	1
GO:0008175	tRNA methyltransferase activity	1/3305	34/18639	0.0294117647058824	0.165871673934324	0.998696545648333	1
GO:0140223	general transcription initiation factor activity	4/3305	68/18639	0.0588235294117647	0.331743347868648	0.998943394617925	1
GO:0008188	neuropeptide receptor activity	2/3305	48/18639	0.0416666666666667	0.234984871406959	0.999041601654061	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/3305	48/18639	0.0416666666666667	0.234984871406959	0.999041601654061	1
GO:0016835	carbon-oxygen lyase activity	5/3305	79/18639	0.0632911392405063	0.356939045175128	0.999171913912036	1
GO:0030280	structural constituent of skin epidermis	1/3305	37/18639	0.027027027027027	0.152422619291001	0.99927512025087	1
GO:0000049	tRNA binding	5/3305	80/18639	0.0625	0.352477307110439	0.999285865410709	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/3305	73/18639	0.0547945205479452	0.309021200754357	0.99951497655119	1
GO:0004812	aminoacyl-tRNA ligase activity	1/3305	41/18639	0.024390243902439	0.137552119847976	0.999668546809006	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/3305	41/18639	0.024390243902439	0.137552119847976	0.999668546809006	1
GO:0030594	neurotransmitter receptor activity	6/3305	97/18639	0.0618556701030928	0.348843520439197	0.999771713394921	1
GO:0008168	methyltransferase activity	19/3305	204/18639	0.0931372549019608	0.525260300792026	0.999772269498756	1
GO:0016741	transferase activity, transferring one-carbon groups	19/3305	215/18639	0.0883720930232558	0.498386517960806	0.999932301931823	1
GO:0003730	mRNA 3'-UTR binding	24/3305	262/18639	0.0916030534351145	0.516607961566445	0.99997266129853	1
GO:0098960	postsynaptic neurotransmitter receptor activity	2/3305	69/18639	0.0289855072463768	0.163467736630928	0.999978037111221	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/3305	56/18639	0.0178571428571429	0.100707802031554	0.99998240907464	1
GO:0140098	catalytic activity, acting on RNA	39/3305	387/18639	0.10077519379845	0.568335502937762	0.999992376252589	1
GO:0140101	catalytic activity, acting on a tRNA	8/3305	139/18639	0.0575539568345324	0.324583419497382	0.999992511185257	1
GO:0008173	RNA methyltransferase activity	1/3305	67/18639	0.0149253731343284	0.0841736852801048	0.999997960761706	1
GO:0016874	ligase activity	10/3305	167/18639	0.0598802395209581	0.337702809207606	0.999998063131046	1
GO:0003735	structural constituent of ribosome	1/3305	175/18639	0.00571428571428571	0.0322264966500973	0.999999999999999	1
GO:0030371	translation repressor activity	8/3305	329/18639	0.0243161094224924	0.137134028298286	1	1
GO:0045182	translation regulator activity	12/3305	356/18639	0.0337078651685393	0.190100120688776	1	1
GO:1903231	mRNA base-pairing translational repressor activity	1/3305	298/18639	0.00335570469798658	0.0189249560864665	1	1