ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	131/2581	489/18639	0.267893660531697	1.9346260901396	1.64672855743527e-14	1.25757108421196e-11
GO:0060589	nucleoside-triphosphatase regulator activity	131/2581	490/18639	0.26734693877551	1.93067787362911	1.94821236903479e-14	1.25757108421196e-11
GO:0140375	immune receptor activity	59/2581	156/18639	0.378205128205128	2.73125353917682	6.35077295567271e-14	2.73294929525782e-11
GO:0005096	GTPase activator activity	79/2581	271/18639	0.291512915129151	2.1051953603612	3.4113025222857e-11	1.10099788906771e-08
GO:0023023	MHC protein complex binding	21/2581	37/18639	0.567567567567568	4.09875702901662	1.18148258742744e-09	3.05058804073764e-07
GO:0019955	cytokine binding	48/2581	144/18639	0.333333333333333	2.407206509105	2.04407577646364e-09	4.3981697123576e-07
GO:0023026	MHC class II protein complex binding	17/2581	27/18639	0.62962962962963	4.54694562830944	5.079991992011e-09	9.36895665955171e-07
GO:0005085	guanyl-nucleotide exchange factor activity	65/2581	230/18639	0.282608695652174	2.04089247511076	7.21646440085745e-09	1.16455694268837e-06
GO:0005126	cytokine receptor binding	73/2581	275/18639	0.265454545454545	1.91701172906907	1.65244420568059e-08	2.37033941059293e-06
GO:0035325	Toll-like receptor binding	11/2581	13/18639	0.846153846153846	6.1106011384973	2.09771943503206e-08	2.70815579062639e-06
GO:0004896	cytokine receptor activity	34/2581	96/18639	0.354166666666667	2.55765691592406	8.3745902440342e-08	9.82872364095286e-06
GO:0004674	protein serine/threonine kinase activity	100/2581	433/18639	0.23094688221709	1.66781051439145	1.05587694714908e-07	1.13594761564122e-05
GO:0044389	ubiquitin-like protein ligase binding	79/2581	322/18639	0.245341614906832	1.77176379707418	1.70784579402642e-07	1.69602224622163e-05
GO:0106310	protein serine kinase activity	86/2581	361/18639	0.238227146814404	1.72038581537144	1.98232663729816e-07	1.82798834910852e-05
GO:0003779	actin binding	100/2581	443/18639	0.225733634311512	1.6301624215158	3.35204008889206e-07	2.88498916983977e-05
GO:0042277	peptide binding	64/2581	249/18639	0.257028112449799	1.85615923593638	4.35219659150579e-07	3.32005200488452e-05
GO:0031625	ubiquitin protein ligase binding	74/2581	302/18639	0.245033112582781	1.76953591066659	4.3718732829618e-07	3.32005200488452e-05
GO:0019902	phosphatase binding	52/2581	190/18639	0.273684210526316	1.97644323905463	6.64928968546991e-07	4.76901832441203e-05
GO:0140996	histone H3 kinase activity	83/2581	357/18639	0.23249299719888	1.67897596853542	9.39757186715442e-07	6.38540277920861e-05
GO:0001540	amyloid-beta binding	29/2581	83/18639	0.349397590361446	2.52321646135102	1.01408953896539e-06	6.54594797402159e-05
GO:0035173	histone kinase activity	83/2581	360/18639	0.230555555555556	1.66498450213096	1.34597686782587e-06	8.27455303030092e-05
GO:0038187	pattern recognition receptor activity	20/2581	48/18639	0.416666666666667	3.00900813638125	2.10943285934019e-06	0.000123785355518554
GO:0141003	histone H2AX kinase activity	81/2581	354/18639	0.228813559322034	1.65240446811445	2.45955892870466e-06	0.00013805611204164
GO:0031267	small GTPase binding	68/2581	283/18639	0.240282685512367	1.7352301337718	2.64048697163918e-06	0.000142036195016091
GO:0042605	peptide antigen binding	19/2581	45/18639	0.422222222222222	3.04912824486633	2.98030251045696e-06	0.000153902821639997
GO:0051020	GTPase binding	73/2581	315/18639	0.231746031746032	1.6735816682349	4.69639658651031e-06	0.000233194153584031
GO:0140313	molecular sequestering activity	21/2581	55/18639	0.381818181818182	2.75734563770209	6.26691321151916e-06	0.000299651294669305
GO:0019903	protein phosphatase binding	40/2581	144/18639	0.277777777777778	2.00600542425417	8.40524696882103e-06	0.000387541922740998
GO:0140297	DNA-binding transcription factor binding	102/2581	488/18639	0.209016393442623	1.5094368684142	9.9514876656241e-06	0.000443012778493818
GO:0042625	ATPase-coupled ion transmembrane transporter activity	12/2581	24/18639	0.5	3.6108097636575	2.58707502064027e-05	0.00104372307863956
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	12/2581	24/18639	0.5	3.6108097636575	2.58707502064027e-05	0.00104372307863956
GO:0046961	proton-transporting ATPase activity, rotational mechanism	12/2581	24/18639	0.5	3.6108097636575	2.58707502064027e-05	0.00104372307863956
GO:0003924	GTPase activity	73/2581	331/18639	0.220543806646526	1.59268346070693	2.86038176426408e-05	0.00111901601747422
GO:0038024	cargo receptor activity	22/2581	65/18639	0.338461538461538	2.44424045539892	3.5126934850671e-05	0.00133379037918283
GO:0005543	phospholipid binding	101/2581	497/18639	0.203219315895372	1.46757257999761	3.65843143049413e-05	0.00134943856479084
GO:0046332	SMAD binding	25/2581	79/18639	0.316455696202532	2.28532263522626	3.87734632175541e-05	0.00139045947260729
GO:0033218	amide binding	57/2581	247/18639	0.230769230769231	1.66652758322654	5.60708438204139e-05	0.00191162215145721
GO:0140311	protein sequestering activity	14/2581	33/18639	0.424242424242424	3.06371737522454	5.62677318012192e-05	0.00191162215145721
GO:0043394	proteoglycan binding	15/2581	37/18639	0.405405405405405	2.92768359215473	5.80958326392162e-05	0.00192312102403149
GO:0043130	ubiquitin binding	29/2581	100/18639	0.29	2.09426966292135	5.97863173068239e-05	0.00192960339107774
GO:0032395	MHC class II receptor activity	7/2581	10/18639	0.7	5.0551336691205	7.91080661956965e-05	0.00249093935264986
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	74/2581	349/18639	0.212034383954155	1.53123164762553	9.78827250207647e-05	0.00287938926872781
GO:0030246	carbohydrate binding	62/2581	280/18639	0.221428571428571	1.59907289533403	9.79170260960338e-05	0.00287938926872781
GO:0035402	histone H3T11 kinase activity	56/2581	247/18639	0.226720647773279	1.63729025720502	0.000107634727195254	0.00287938926872781
GO:0035403	histone H3T6 kinase activity	56/2581	247/18639	0.226720647773279	1.63729025720502	0.000107634727195254	0.00287938926872781
GO:0019207	kinase regulator activity	63/2581	287/18639	0.219512195121951	1.58523355477646	0.000112503930054896	0.00287938926872781
GO:0004679	AMP-activated protein kinase activity	56/2581	248/18639	0.225806451612903	1.63068828036145	0.0001206094557062	0.00287938926872781
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	55/2581	243/18639	0.226337448559671	1.63452293828117	0.000129313330245931	0.00287938926872781
GO:0019003	GDP binding	23/2581	75/18639	0.306666666666667	2.2146299883766	0.000133424690342816	0.00287938926872781
GO:0004713	protein tyrosine kinase activity	36/2581	140/18639	0.257142857142857	1.85698787845243	0.00013421069883764	0.00287938926872781
GO:0019001	guanyl nucleotide binding	82/2581	400/18639	0.205	1.48043200309957	0.000140935865086323	0.00287938926872781
GO:0032561	guanyl ribonucleotide binding	82/2581	400/18639	0.205	1.48043200309957	0.000140935865086323	0.00287938926872781
GO:0016798	hydrolase activity, acting on glycosyl bonds	34/2581	130/18639	0.261538461538462	1.88873126099008	0.000142889645437816	0.00287938926872781
GO:0035091	phosphatidylinositol binding	62/2581	284/18639	0.21830985915493	1.57655074187863	0.000149292616346581	0.00287938926872781
GO:0017124	SH3 domain binding	31/2581	115/18639	0.269565217391304	1.94669743779795	0.000152462518670664	0.00287938926872781
GO:0004676	3-phosphoinositide-dependent protein kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0004711	ribosomal protein S6 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0035175	histone H3S10 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0035979	histone H2AXS139 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0044022	histone H3S28 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0044023	histone H4S1 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0044024	histone H2AS1 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0044025	histone H2BS14 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0072354	histone H3T3 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0072371	histone H2AS121 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0072518	Rho-dependent protein serine/threonine kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0140823	histone H2BS36 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0140855	histone H3S57 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0140995	histone H2A kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0140997	histone H4 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0140998	histone H2B kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:1990244	histone H2AT120 kinase activity	55/2581	245/18639	0.224489795918367	1.62117989388704	0.00016203693395578	0.00287938926872781
GO:0005525	GTP binding	78/2581	378/18639	0.206349206349206	1.49017545801738	0.000162815969494291	0.00287938926872781
GO:0004677	DNA-dependent protein kinase activity	55/2581	246/18639	0.223577235772358	1.61458973171677	0.000181068893165487	0.00311679921435525
GO:0140857	histone H3T45 kinase activity	55/2581	246/18639	0.223577235772358	1.61458973171677	0.000181068893165487	0.00311679921435525
GO:0004857	enzyme inhibitor activity	84/2581	416/18639	0.201923076923077	1.45821163532322	0.000199166471211607	0.003383209399134
GO:0004715	non-membrane spanning protein tyrosine kinase activity	16/2581	45/18639	0.355555555555556	2.56768694304533	0.000209304750080233	0.00346426195325103
GO:0046915	transition metal ion transmembrane transporter activity	16/2581	45/18639	0.355555555555556	2.56768694304533	0.000209304750080233	0.00346426195325103
GO:0051015	actin filament binding	48/2581	209/18639	0.229665071770335	1.65855376703885	0.000234328087820356	0.00382933621995038
GO:0001217	DNA-binding transcription repressor activity	60/2581	278/18639	0.215827338129496	1.55862291956439	0.000261132988793289	0.0042140336066517
GO:0030228	lipoprotein particle receptor activity	9/2581	18/18639	0.5	3.6108097636575	0.000274489203445418	0.00432153123961018
GO:0032393	MHC class I receptor activity	9/2581	18/18639	0.5	3.6108097636575	0.000274489203445418	0.00432153123961018
GO:0032182	ubiquitin-like protein binding	31/2581	120/18639	0.258333333333333	1.86558504455637	0.000347569672183556	0.00540617405769845
GO:0001968	fibronectin binding	12/2581	30/18639	0.4	2.888647810926	0.000369893412570993	0.00562790729627105
GO:0005504	fatty acid binding	16/2581	47/18639	0.340425531914894	2.45842366887319	0.000370543857616607	0.00562790729627105
GO:0070008	serine-type exopeptidase activity	7/2581	12/18639	0.583333333333333	4.21261139093375	0.000404371188509585	0.00607026981820784
GO:0000149	SNARE binding	28/2581	106/18639	0.264150943396226	1.90759761098887	0.000445822773479345	0.00661560000645786
GO:0001618	virus receptor activity	23/2581	81/18639	0.283950617283951	2.05058332257092	0.000465886922404076	0.0068347729184507
GO:0005518	collagen binding	21/2581	72/18639	0.291666666666667	2.10630569546687	0.00054710057143925	0.00788876428540655
GO:0070851	growth factor receptor binding	34/2581	139/18639	0.244604316546763	1.76643930883964	0.000550951936529156	0.00788876428540655
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	93/2581	484/18639	0.192148760330579	1.38762523975267	0.000556063168065063	0.00788876428540655
GO:0140272	exogenous protein binding	23/2581	82/18639	0.280487804878049	2.02557620888104	0.000563870983822801	0.00791258087081778
GO:0001216	DNA-binding transcription activator activity	94/2581	491/18639	0.191446028513238	1.3825503779381	0.000590457107063127	0.0081965604862204
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	14/2581	40/18639	0.35	2.52756683456025	0.000618565291853598	0.00849540204024463
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	17/2581	54/18639	0.314814814814815	2.27347281415472	0.00069217051057217	0.00940623293840707
GO:0017154	semaphorin receptor activity	7/2581	13/18639	0.538461538461538	3.88856436086192	0.000771415387386103	0.0102669821145924
GO:0032396	inhibitory MHC class I receptor activity	7/2581	13/18639	0.538461538461538	3.88856436086192	0.000771415387386103	0.0102669821145924
GO:0070513	death domain binding	6/2581	10/18639	0.6	4.332971716389	0.000891653542473588	0.0115803997940691
GO:1905394	retromer complex binding	6/2581	10/18639	0.6	4.332971716389	0.000891653542473588	0.0115803997940691
GO:0031406	carboxylic acid binding	42/2581	187/18639	0.224598930481283	1.6219680221777	0.000897010053762133	0.0115803997940691
GO:0003725	double-stranded RNA binding	21/2581	75/18639	0.28	2.0220534676482	0.000985618750035313	0.012546857201516
GO:0008429	phosphatidylethanolamine binding	8/2581	17/18639	0.470588235294118	3.3984091893247	0.00101074604876659	0.012546857201516
GO:0008484	sulfuric ester hydrolase activity	8/2581	17/18639	0.470588235294118	3.3984091893247	0.00101074604876659	0.012546857201516
GO:0036041	long-chain fatty acid binding	8/2581	17/18639	0.470588235294118	3.3984091893247	0.00101074604876659	0.012546857201516
GO:0043177	organic acid binding	42/2581	189/18639	0.222222222222222	1.60480433940333	0.0011206873669829	0.0136627465709737
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	9/2581	21/18639	0.428571428571429	3.09497979742071	0.00112180568282201	0.0136627465709737
GO:0015026	coreceptor activity	18/2581	61/18639	0.295081967213115	2.13096969658475	0.0011434353595061	0.0137960284964708
GO:0001784	phosphotyrosine residue binding	15/2581	47/18639	0.319148936170213	2.30477218956862	0.00120070882593148	0.0143529175396069
GO:1901981	phosphatidylinositol phosphate binding	41/2581	185/18639	0.221621621621622	1.60046703037792	0.00134608335487687	0.015943060652716
GO:0061134	peptidase regulator activity	48/2581	226/18639	0.212389380530973	1.53379529783681	0.00145755017590441	0.0170108351585728
GO:0042578	phosphoric ester hydrolase activity	71/2581	363/18639	0.195592286501377	1.41249307559054	0.00146258923516777	0.0170108351585728
GO:0019838	growth factor binding	32/2581	136/18639	0.235294117647059	1.69920459466235	0.00157419669962012	0.0181164843754856
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	55/2581	268/18639	0.205223880597015	1.48204878359076	0.0015886703886309	0.0181164843754856
GO:0004706	JUN kinase kinase kinase activity	8/2581	18/18639	0.444444444444444	3.20960867880666	0.00159975152502352	0.0181164843754856
GO:0043548	phosphatidylinositol 3-kinase binding	10/2581	26/18639	0.384615384615385	2.77754597204423	0.00162277080188634	0.0182173661324805
GO:0032934	sterol binding	19/2581	68/18639	0.279411764705882	2.01780545616154	0.00172866127681189	0.0183461676774117
GO:0005114	type II transforming growth factor beta receptor binding	6/2581	11/18639	0.545454545454545	3.93906519671727	0.00173193085695093	0.0183461676774117
GO:0008432	JUN kinase binding	6/2581	11/18639	0.545454545454545	3.93906519671727	0.00173193085695093	0.0183461676774117
GO:0019864	IgG binding	6/2581	11/18639	0.545454545454545	3.93906519671727	0.00173193085695093	0.0183461676774117
GO:0042608	T cell receptor binding	6/2581	11/18639	0.545454545454545	3.93906519671727	0.00173193085695093	0.0183461676774117
GO:0001221	transcription coregulator binding	28/2581	115/18639	0.243478260869565	1.75830736317235	0.00174793077019491	0.0183461676774117
GO:0035401	histone H3Y41 kinase activity	28/2581	115/18639	0.243478260869565	1.75830736317235	0.00174793077019491	0.0183461676774117
GO:0140801	histone H2AXY142 kinase activity	28/2581	115/18639	0.243478260869565	1.75830736317235	0.00174793077019491	0.0183461676774117
GO:0003925	G protein activity	16/2581	54/18639	0.296296296296296	2.13973911920444	0.00201150507223918	0.020814609581221
GO:0033293	monocarboxylic acid binding	21/2581	79/18639	0.265822784810127	1.91967101359006	0.00201535724062946	0.020814609581221
GO:0005041	low-density lipoprotein particle receptor activity	7/2581	15/18639	0.466666666666667	3.370089112747	0.0022448345995009	0.0228036632591061
GO:0120283	protein serine/threonine kinase binding	7/2581	15/18639	0.466666666666667	3.370089112747	0.0022448345995009	0.0228036632591061
GO:0005044	scavenger receptor activity	10/2581	27/18639	0.37037037037037	2.67467389900555	0.00226093640369139	0.0228036632591061
GO:0032813	tumor necrosis factor receptor superfamily binding	15/2581	50/18639	0.3	2.1664858581945	0.00239945592406962	0.0237524852739301
GO:0005484	SNAP receptor activity	12/2581	36/18639	0.333333333333333	2.407206509105	0.00240706288554109	0.0237524852739301
GO:0019887	protein kinase regulator activity	52/2581	255/18639	0.203921568627451	1.4726439820407	0.00241020570943829	0.0237524852739301
GO:0015245	fatty acid transmembrane transporter activity	8/2581	19/18639	0.421052631578947	3.04068190623789	0.00243039960999836	0.0237700446705143
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/2581	41/18639	0.317073170731707	2.28978180134378	0.0026702850301902	0.0259198343907936
GO:0071813	lipoprotein particle binding	11/2581	32/18639	0.34375	2.48243171251453	0.00274813831792275	0.0260871071208696
GO:0071814	protein-lipid complex binding	11/2581	32/18639	0.34375	2.48243171251453	0.00274813831792275	0.0260871071208696
GO:0120015	sterol transfer activity	11/2581	32/18639	0.34375	2.48243171251453	0.00274813831792275	0.0260871071208696
GO:0043178	alcohol binding	23/2581	92/18639	0.25	1.80540488182875	0.00301222904910528	0.0283853116963132
GO:0046966	nuclear thyroid hormone receptor binding	10/2581	28/18639	0.357142857142857	2.57914983118393	0.00308595368436152	0.0288693203370342
GO:0002020	protease binding	31/2581	136/18639	0.227941176470588	1.64610445107915	0.00311515532809418	0.0289328455292776
GO:0042626	ATPase-coupled transmembrane transporter activity	24/2581	98/18639	0.244897959183673	1.76855988424041	0.00330898199683216	0.0305135411279308
GO:0035035	histone acetyltransferase binding	9/2581	24/18639	0.375	2.70810732274312	0.00338104813787379	0.0306300406425502
GO:0050431	transforming growth factor beta binding	9/2581	24/18639	0.375	2.70810732274312	0.00338104813787379	0.0306300406425502
GO:0019209	kinase activator activity	33/2581	148/18639	0.222972972972973	1.6102259756851	0.00339279303786575	0.0306300406425502
GO:0016922	nuclear receptor binding	31/2581	137/18639	0.226277372262774	1.63408909012237	0.00350370542705899	0.0308905936234833
GO:0005149	interleukin-1 receptor binding	7/2581	16/18639	0.4375	3.15945854320031	0.00351736426231762	0.0308905936234833
GO:0005324	long-chain fatty acid transmembrane transporter activity	7/2581	16/18639	0.4375	3.15945854320031	0.00351736426231762	0.0308905936234833
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	7/2581	16/18639	0.4375	3.15945854320031	0.00351736426231762	0.0308905936234833
GO:0019239	deaminase activity	11/2581	33/18639	0.333333333333333	2.407206509105	0.00361384012170137	0.0315234297102464
GO:0061135	endopeptidase regulator activity	39/2581	184/18639	0.21195652173913	1.53066935633307	0.00398186290416876	0.0345005705320931
GO:0005178	integrin binding	35/2581	161/18639	0.217391304347826	1.56991728854674	0.00403267777435607	0.0347079133779579
GO:0004629	phospholipase C activity	10/2581	29/18639	0.344827586206897	2.49021363010862	0.0041338109535333	0.0351101969803388
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	10/2581	29/18639	0.344827586206897	2.49021363010862	0.0041338109535333	0.0351101969803388
GO:0008375	acetylglucosaminyltransferase activity	13/2581	43/18639	0.302325581395349	2.18328032221151	0.00424710616888325	0.035836693228943
GO:0005507	copper ion binding	17/2581	63/18639	0.26984126984127	1.94869098356119	0.00438297780320669	0.0367430152203885
GO:0019787	ubiquitin-like protein transferase activity	87/2581	479/18639	0.181628392484342	1.31165114587976	0.0044117038936835	0.0367452240435187
GO:0120020	cholesterol transfer activity	9/2581	25/18639	0.36	2.5997830298334	0.0046424052959759	0.0384188797250314
GO:0008035	high-density lipoprotein particle binding	6/2581	13/18639	0.461538461538462	3.33305516645307	0.00502069778654042	0.0412848461300871
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/2581	39/18639	0.307692307692308	2.22203677763538	0.00505565027078704	0.0413091424024435
GO:0035591	signaling adaptor activity	29/2581	129/18639	0.224806201550388	1.62346485497779	0.00510991288369464	0.0414899215902502
GO:0030169	low-density lipoprotein particle binding	7/2581	17/18639	0.411764705882353	2.97360804065911	0.00527199701180334	0.0425384258889882
GO:0015485	cholesterol binding	15/2581	54/18639	0.277777777777778	2.00600542425417	0.00539072279958581	0.0432262306476104
GO:0016298	lipase activity	29/2581	130/18639	0.223076923076923	1.61097666378565	0.00572711471438003	0.0456401549152137
GO:0061631	ubiquitin conjugating enzyme activity	11/2581	35/18639	0.314285714285714	2.26965185144186	0.00599145348851996	0.0474537819244127
GO:0005160	transforming growth factor beta receptor binding	9/2581	26/18639	0.346153846153846	2.49979137483981	0.0062410353222586	0.0488313733396112
GO:0019865	immunoglobulin binding	9/2581	26/18639	0.346153846153846	2.49979137483981	0.0062410353222586	0.0488313733396112
GO:0015101	organic cation transmembrane transporter activity	20/2581	81/18639	0.246913580246914	1.78311593267037	0.00630655420117055	0.04904675586573
GO:0004722	protein serine/threonine phosphatase activity	24/2581	103/18639	0.233009708737864	1.68270746267534	0.00646512739973984	0.0499467791374385
GO:0141110	transporter inhibitor activity	13/2581	45/18639	0.288888888888889	2.08624564122433	0.00649965832307488	0.0499467791374385
GO:0008081	phosphoric diester hydrolase activity	21/2581	87/18639	0.241379310344828	1.74314954107603	0.00686711681114644	0.0523030105068751
GO:0004842	ubiquitin-protein transferase activity	81/2581	449/18639	0.180400890868597	1.30278659624168	0.0069629915184142	0.0523030105068751
GO:0005131	growth hormone receptor binding	5/2581	10/18639	0.5	3.6108097636575	0.00696833292578041	0.0523030105068751
GO:0005381	iron ion transmembrane transporter activity	5/2581	10/18639	0.5	3.6108097636575	0.00696833292578041	0.0523030105068751
GO:0033691	sialic acid binding	8/2581	22/18639	0.363636363636364	2.62604346447818	0.00700931927539067	0.052306538638898
GO:0016411	acylglycerol O-acyltransferase activity	10/2581	31/18639	0.32258064516129	2.32955468623064	0.0070555393314388	0.0523488579131465
GO:0004866	endopeptidase inhibitor activity	34/2581	161/18639	0.211180124223602	1.52506250887397	0.00723849389823689	0.0533994035578505
GO:0035615	clathrin adaptor activity	7/2581	18/18639	0.388888888888889	2.80840759395583	0.00760888050339051	0.0558128677833929
GO:0042169	SH2 domain binding	12/2581	41/18639	0.292682926829268	2.11364473970195	0.00784332113533242	0.0572075004842607
GO:0016755	aminoacyltransferase activity	88/2581	496/18639	0.17741935483871	1.28125507742685	0.00795309064148764	0.0576822472930367
GO:0004364	glutathione transferase activity	9/2581	27/18639	0.333333333333333	2.407206509105	0.00823108478154221	0.0593649745976033
GO:0030414	peptidase inhibitor activity	35/2581	169/18639	0.207100591715976	1.49560167725458	0.00886245186114607	0.0635634741818865
GO:0004721	phosphoprotein phosphatase activity	36/2581	175/18639	0.205714285714286	1.48559030276194	0.00893876939216725	0.0637566369352923
GO:1990782	protein tyrosine kinase binding	26/2581	117/18639	0.222222222222222	1.60480433940333	0.00901067807667085	0.0639164032801212
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	8/2581	23/18639	0.347826086956522	2.51186766167478	0.00946478009747236	0.0656937156227786
GO:0004602	glutathione peroxidase activity	8/2581	23/18639	0.347826086956522	2.51186766167478	0.00946478009747236	0.0656937156227786
GO:0042171	lysophosphatidic acid acyltransferase activity	8/2581	23/18639	0.347826086956522	2.51186766167478	0.00946478009747236	0.0656937156227786
GO:0071617	lysophospholipid acyltransferase activity	8/2581	23/18639	0.347826086956522	2.51186766167478	0.00946478009747236	0.0656937156227786
GO:0004860	protein kinase inhibitor activity	20/2581	84/18639	0.238095238095238	1.71943322078928	0.00959399373457834	0.0661068121239687
GO:0048487	beta-tubulin binding	12/2581	42/18639	0.285714285714286	2.06331986494714	0.00962670850449738	0.0661068121239687
GO:0030145	manganese ion binding	17/2581	68/18639	0.25	1.80540488182875	0.00991079199960634	0.0676975263041893
GO:0019210	kinase inhibitor activity	21/2581	90/18639	0.233333333333333	1.6850445563735	0.0102342255229657	0.0695388692113094
GO:0003712	transcription coregulator activity	87/2581	495/18639	0.175757575757576	1.26925434116445	0.010535058605088	0.0712081709904116
GO:0097001	ceramide binding	7/2581	19/18639	0.368421052631579	2.66059666795816	0.0106296610245359	0.0714733978264368
GO:0140789	histone phosphatase activity	29/2581	136/18639	0.213235294117647	1.53990416391276	0.0108725324575529	0.0727276652989678
GO:0008238	exopeptidase activity	23/2581	102/18639	0.225490196078431	1.62840440321809	0.0113183029035748	0.0740766989004964
GO:0047676	arachidonate-CoA ligase activity	5/2581	11/18639	0.454545454545455	3.28255433059772	0.0113320013164716	0.0740766989004964
GO:0097493	structural molecule activity conferring elasticity	5/2581	11/18639	0.454545454545455	3.28255433059772	0.0113320013164716	0.0740766989004964
GO:0140031	phosphorylation-dependent protein binding	5/2581	11/18639	0.454545454545455	3.28255433059772	0.0113320013164716	0.0740766989004964
GO:0019956	chemokine binding	10/2581	33/18639	0.303030303030303	2.18836955373182	0.0113611048662264	0.0740766989004964
GO:0140693	molecular condensate scaffold activity	13/2581	48/18639	0.270833333333333	1.95585528864781	0.0115476550064879	0.0749146864993765
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	21/2581	91/18639	0.230769230769231	1.66652758322654	0.0116134324350261	0.0749647063680936
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	15/2581	59/18639	0.254237288135593	1.83600496457161	0.0127393972606645	0.0814186230867221
GO:0045309	protein phosphorylated amino acid binding	15/2581	59/18639	0.254237288135593	1.83600496457161	0.0127393972606645	0.0814186230867221
GO:0052689	carboxylic ester hydrolase activity	21/2581	92/18639	0.228260869565217	1.64841315297407	0.0131371677073548	0.0835472094098281
GO:0001222	transcription corepressor binding	13/2581	49/18639	0.26530612244898	1.91593987459377	0.0137745158620089	0.0871710783228111
GO:0016248	channel inhibitor activity	12/2581	44/18639	0.272727272727273	1.96953259835863	0.0141208219929206	0.088634539401774
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	10/2581	34/18639	0.294117647058824	2.12400574332794	0.0141430790989663	0.088634539401774
GO:0016004	phospholipase activator activity	7/2581	20/18639	0.35	2.52756683456025	0.0144343269776206	0.090022783227576
GO:0031490	chromatin DNA binding	27/2581	128/18639	0.2109375	1.52331036904301	0.0156533092387909	0.097155876092688
GO:0005024	transforming growth factor beta receptor activity	6/2581	16/18639	0.375	2.70810732274312	0.0162072771530643	0.0986973474603504
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	6/2581	16/18639	0.375	2.70810732274312	0.0162072771530643	0.0986973474603504
GO:0004709	MAP kinase kinase kinase activity	8/2581	25/18639	0.32	2.3109182487408	0.0162074652684696	0.0986973474603504
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/2581	25/18639	0.32	2.3109182487408	0.0162074652684696	0.0986973474603504
GO:0008009	chemokine activity	12/2581	45/18639	0.266666666666667	1.925765207284	0.0168921542365009	0.101172956528163
GO:0031624	ubiquitin conjugating enzyme binding	9/2581	30/18639	0.3	2.1664858581945	0.0171082306046423	0.101172956528163
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	19/2581	83/18639	0.228915662650602	1.65314181950584	0.0172180268692066	0.101172956528163
GO:0004875	complement receptor activity	5/2581	12/18639	0.416666666666667	3.00900813638125	0.017240937595814	0.101172956528163
GO:0005078	MAP-kinase scaffold activity	5/2581	12/18639	0.416666666666667	3.00900813638125	0.017240937595814	0.101172956528163
GO:0008603	cAMP-dependent protein kinase regulator activity	5/2581	12/18639	0.416666666666667	3.00900813638125	0.017240937595814	0.101172956528163
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/2581	12/18639	0.416666666666667	3.00900813638125	0.017240937595814	0.101172956528163
GO:0035259	nuclear glucocorticoid receptor binding	5/2581	12/18639	0.416666666666667	3.00900813638125	0.017240937595814	0.101172956528163
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	20/2581	89/18639	0.224719101123595	1.62283584883483	0.0180037757456501	0.104697632827182
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	20/2581	89/18639	0.224719101123595	1.62283584883483	0.0180037757456501	0.104697632827182
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	27/2581	130/18639	0.207692307692308	1.49987482490388	0.0189939411954634	0.109210402335615
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/2581	21/18639	0.333333333333333	2.407206509105	0.0191181649324935	0.109210402335615
GO:0051010	microtubule plus-end binding	7/2581	21/18639	0.333333333333333	2.407206509105	0.0191181649324935	0.109210402335615
GO:0140312	cargo adaptor activity	7/2581	21/18639	0.333333333333333	2.407206509105	0.0191181649324935	0.109210402335615
GO:0015399	primary active transmembrane transporter activity	33/2581	166/18639	0.198795180722892	1.43562315904455	0.01935067541309	0.110051638582816
GO:0015179	L-amino acid transmembrane transporter activity	15/2581	62/18639	0.241935483870968	1.74716601467298	0.0199389842159209	0.112549917813669
GO:0004180	carboxypeptidase activity	12/2581	46/18639	0.260869565217391	1.88390074625609	0.0200533209698428	0.112549917813669
GO:0140793	histone H2AXY142 phosphatase activity	20/2581	90/18639	0.222222222222222	1.60480433940333	0.0202236472378457	0.112549917813669
GO:0001637	G protein-coupled chemoattractant receptor activity	8/2581	26/18639	0.307692307692308	2.22203677763538	0.0206369896890079	0.112549917813669
GO:0004435	phosphatidylinositol phospholipase C activity	8/2581	26/18639	0.307692307692308	2.22203677763538	0.0206369896890079	0.112549917813669
GO:0004950	chemokine receptor activity	8/2581	26/18639	0.307692307692308	2.22203677763538	0.0206369896890079	0.112549917813669
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	8/2581	26/18639	0.307692307692308	2.22203677763538	0.0206369896890079	0.112549917813669
GO:0008198	ferrous iron binding	8/2581	26/18639	0.307692307692308	2.22203677763538	0.0206369896890079	0.112549917813669
GO:0050681	nuclear androgen receptor binding	8/2581	26/18639	0.307692307692308	2.22203677763538	0.0206369896890079	0.112549917813669
GO:0001530	lipopolysaccharide binding	11/2581	41/18639	0.268292682926829	1.93750767806012	0.0207489391476787	0.112549917813669
GO:0061650	ubiquitin-like protein conjugating enzyme activity	11/2581	41/18639	0.268292682926829	1.93750767806012	0.0207489391476787	0.112549917813669
GO:0031072	heat shock protein binding	27/2581	131/18639	0.206106870229008	1.48842539875958	0.0208626388291437	0.112693166227718
GO:0004869	cysteine-type endopeptidase inhibitor activity	10/2581	36/18639	0.277777777777778	2.00600542425417	0.0211864770313425	0.113676006325236
GO:0005164	tumor necrosis factor receptor binding	9/2581	31/18639	0.290322580645161	2.09659921760758	0.0212206952164074	0.113676006325236
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/2581	17/18639	0.352941176470588	2.54880689199353	0.0221719754119339	0.11828107544135
GO:0004620	phospholipase activity	23/2581	109/18639	0.211009174311927	1.52382797365362	0.0242029186767738	0.128584230500885
GO:0016209	antioxidant activity	19/2581	86/18639	0.22093023255814	1.5954740816161	0.0245645562696539	0.129970664525095
GO:0005035	death receptor activity	5/2581	13/18639	0.384615384615385	2.77754597204423	0.0248785874766101	0.130562018017494
GO:0035673	oligopeptide transmembrane transporter activity	5/2581	13/18639	0.384615384615385	2.77754597204423	0.0248785874766101	0.130562018017494
GO:0030295	protein kinase activator activity	28/2581	139/18639	0.201438848920863	1.45471472492676	0.0250748683000337	0.131059331883982
GO:0004683	calcium/calmodulin-dependent protein kinase activity	8/2581	27/18639	0.296296296296296	2.13973911920444	0.0258605285974145	0.132766084316747
GO:0004725	protein tyrosine phosphatase activity	21/2581	98/18639	0.214285714285714	1.54748989871036	0.0258824778171693	0.132766084316747
GO:0043425	bHLH transcription factor binding	9/2581	32/18639	0.28125	2.03108049205734	0.0259974437816393	0.132766084316747
GO:0140296	general transcription initiation factor binding	13/2581	53/18639	0.245283018867925	1.77134063877538	0.0260866021958832	0.132766084316747
GO:0033192	calmodulin-dependent protein phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0140791	histone H2AXS140 phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:1990439	MAP kinase serine/threonine phosphatase activity	18/2581	81/18639	0.222222222222222	1.60480433940333	0.0266354886429414	0.132766084316747
GO:0061659	ubiquitin-like protein ligase activity	65/2581	372/18639	0.174731182795699	1.26184212170827	0.0271333932844557	0.134727733577817
GO:0051087	protein-folding chaperone binding	27/2581	134/18639	0.201492537313433	1.45510244207093	0.0273410181184717	0.135238522570678
GO:0032266	phosphatidylinositol-3-phosphate binding	12/2581	48/18639	0.25	1.80540488182875	0.0276627076203416	0.136307463884966
GO:0051219	phosphoprotein binding	20/2581	93/18639	0.21505376344086	1.5530364574871	0.028161342156079	0.138236854461969
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/2581	43/18639	0.255813953488372	1.84739104187128	0.0291596127719212	0.141355011227775
GO:0008200	ion channel inhibitor activity	11/2581	43/18639	0.255813953488372	1.84739104187128	0.0291596127719212	0.141355011227775
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	6/2581	18/18639	0.333333333333333	2.407206509105	0.0294535228662056	0.141355011227775
GO:0015172	acidic amino acid transmembrane transporter activity	6/2581	18/18639	0.333333333333333	2.407206509105	0.0294535228662056	0.141355011227775
GO:0016854	racemase and epimerase activity	6/2581	18/18639	0.333333333333333	2.407206509105	0.0294535228662056	0.141355011227775
GO:0034185	apolipoprotein binding	6/2581	18/18639	0.333333333333333	2.407206509105	0.0294535228662056	0.141355011227775
GO:0019208	phosphatase regulator activity	24/2581	117/18639	0.205128205128205	1.48135785175692	0.0296413083981482	0.141694995424552
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	18/2581	82/18639	0.219512195121951	1.58523355477646	0.0298536318787591	0.141694995424552
GO:0033549	MAP kinase phosphatase activity	18/2581	82/18639	0.219512195121951	1.58523355477646	0.0298536318787591	0.141694995424552
GO:0042887	amide transmembrane transporter activity	10/2581	38/18639	0.263157894736842	1.90042619139868	0.0304829779867699	0.144152104692014
GO:0004197	cysteine-type endopeptidase activity	19/2581	88/18639	0.215909090909091	1.55921330703392	0.0306453353269812	0.144390977763258
GO:0005158	insulin receptor binding	7/2581	23/18639	0.304347826086957	2.19788420396543	0.0314645380927884	0.147176516948514
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	7/2581	23/18639	0.304347826086957	2.19788420396543	0.0314645380927884	0.147176516948514
GO:0046625	sphingolipid binding	8/2581	28/18639	0.285714285714286	2.06331986494714	0.0319374391790344	0.148313791295444
GO:0051019	mitogen-activated protein kinase binding	8/2581	28/18639	0.285714285714286	2.06331986494714	0.0319374391790344	0.148313791295444
GO:0016763	pentosyltransferase activity	12/2581	49/18639	0.244897959183673	1.76855988424041	0.0321669860284494	0.148422241295516
GO:0098531	ligand-modulated transcription factor activity	14/2581	60/18639	0.233333333333333	1.6850445563735	0.0321907262298563	0.148422241295516
GO:0022853	active monoatomic ion transmembrane transporter activity	24/2581	118/18639	0.203389830508475	1.46880397165729	0.0324864706494955	0.149252788642344
GO:0016791	phosphatase activity	49/2581	273/18639	0.179487179487179	1.29618812028731	0.0327272901603711	0.149825998571061
GO:0005539	glycosaminoglycan binding	44/2581	242/18639	0.181818181818182	1.31302173223909	0.0340891509448794	0.154135476441828
GO:0004065	arylsulfatase activity	5/2581	14/18639	0.357142857142857	2.57914983118393	0.0343849862240485	0.154135476441828
GO:0005161	platelet-derived growth factor receptor binding	5/2581	14/18639	0.357142857142857	2.57914983118393	0.0343849862240485	0.154135476441828
GO:0008191	metalloendopeptidase inhibitor activity	5/2581	14/18639	0.357142857142857	2.57914983118393	0.0343849862240485	0.154135476441828
GO:0019763	immunoglobulin receptor activity	5/2581	14/18639	0.357142857142857	2.57914983118393	0.0343849862240485	0.154135476441828
GO:0061665	SUMO ligase activity	5/2581	14/18639	0.357142857142857	2.57914983118393	0.0343849862240485	0.154135476441828
GO:0008374	O-acyltransferase activity	13/2581	55/18639	0.236363636363636	1.70692825191082	0.0346342551374299	0.154715651842291
GO:0042379	chemokine receptor binding	16/2581	72/18639	0.222222222222222	1.60480433940333	0.0352234075815498	0.156804893750968
GO:0019905	syntaxin binding	14/2581	61/18639	0.229508196721311	1.65742087512147	0.0366376610184679	0.162540276202206
GO:0017018	myosin phosphatase activity	18/2581	84/18639	0.214285714285714	1.54748989871036	0.037145303977495	0.164228039160774
GO:0022804	active transmembrane transporter activity	77/2581	457/18639	0.168490153172867	1.21677178031347	0.0375217576740358	0.164636983000795
GO:0043395	heparan sulfate proteoglycan binding	6/2581	19/18639	0.315789473684211	2.28051142967842	0.0381414591008223	0.164636983000795
GO:0004090	carbonyl reductase (NADPH) activity	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0004955	prostaglandin receptor activity	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0005031	tumor necrosis factor receptor activity	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0005345	purine nucleobase transmembrane transporter activity	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0008239	dipeptidyl-peptidase activity	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0043422	protein kinase B binding	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0071723	lipopeptide binding	4/2581	10/18639	0.4	2.888647810926	0.0385130665114175	0.164636983000795
GO:0005496	steroid binding	22/2581	108/18639	0.203703703703704	1.47107064445305	0.0387419206559638	0.165068711441747
GO:0051861	glycolipid binding	8/2581	29/18639	0.275862068965517	1.99217090408689	0.0389197967029375	0.165281110340435
GO:0019957	C-C chemokine binding	7/2581	24/18639	0.291666666666667	2.10630569546687	0.039270728922707	0.165681408624885
GO:0060229	lipase activator activity	7/2581	24/18639	0.291666666666667	2.10630569546687	0.039270728922707	0.165681408624885
GO:0170055	lipid transmembrane transporter activity	13/2581	56/18639	0.232142857142857	1.67644739026955	0.0395868886663872	0.166471248430964
GO:0061791	GTPase motor activity	10/2581	40/18639	0.25	1.80540488182875	0.0423345772738775	0.176873589840051
GO:1990606	membrane scission GTPase motor activity	10/2581	40/18639	0.25	1.80540488182875	0.0423345772738775	0.176873589840051
GO:0001664	G protein-coupled receptor binding	52/2581	297/18639	0.175084175084175	1.26439129771172	0.0426651486088015	0.177265230922909
GO:0030544	Hsp70 protein binding	12/2581	51/18639	0.235294117647059	1.69920459466235	0.0427029332432415	0.177265230922909
GO:1990841	promoter-specific chromatin binding	15/2581	68/18639	0.220588235294118	1.59300430749595	0.0430149974322638	0.177988338734143
GO:0048029	monosaccharide binding	16/2581	74/18639	0.216216216216216	1.56143124914919	0.044173741420329	0.182199042088322
GO:0005154	epidermal growth factor receptor binding	9/2581	35/18639	0.257142857142857	1.85698787845243	0.0447654081888798	0.183660135391623
GO:0004601	peroxidase activity	13/2581	57/18639	0.228070175438596	1.64703603254552	0.0450191750842153	0.183660135391623
GO:0016504	peptidase activator activity	13/2581	57/18639	0.228070175438596	1.64703603254552	0.0450191750842153	0.183660135391623
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	25/2581	128/18639	0.1953125	1.41047256392871	0.0456307871955223	0.183660135391623
GO:0004467	long-chain fatty acid-CoA ligase activity	5/2581	15/18639	0.333333333333333	2.407206509105	0.0458531994265555	0.183660135391623
GO:0015929	hexosaminidase activity	5/2581	15/18639	0.333333333333333	2.407206509105	0.0458531994265555	0.183660135391623
GO:0017081	chloride channel regulator activity	5/2581	15/18639	0.333333333333333	2.407206509105	0.0458531994265555	0.183660135391623
GO:0047372	monoacylglycerol lipase activity	5/2581	15/18639	0.333333333333333	2.407206509105	0.0458531994265555	0.183660135391623
GO:0050700	CARD domain binding	5/2581	15/18639	0.333333333333333	2.407206509105	0.0458531994265555	0.183660135391623
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	24/2581	122/18639	0.19672131147541	1.42064646438983	0.0459505993272612	0.183660135391623
GO:0051721	protein phosphatase 2A binding	8/2581	30/18639	0.266666666666667	1.925765207284	0.0468512752841357	0.186682087629072
GO:0031418	L-ascorbic acid binding	6/2581	20/18639	0.3	2.1664858581945	0.0483016585821944	0.191869049937271
GO:0030159	signaling receptor complex adaptor activity	12/2581	52/18639	0.230769230769231	1.66652758322654	0.0487797024780029	0.193060173970845
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	41/2581	229/18639	0.179039301310044	1.29295371449744	0.0489006017726308	0.193060173970845
GO:0001727	lipid kinase activity	10/2581	41/18639	0.24390243902439	1.76137061641829	0.0492976863468448	0.194034491078587
GO:0030971	receptor tyrosine kinase binding	17/2581	81/18639	0.209876543209877	1.51564854276981	0.0499281181945423	0.195918542824177
GO:0051213	dioxygenase activity	19/2581	93/18639	0.204301075268817	1.47538463461274	0.0506664067927126	0.198213124755733
GO:0061980	regulatory RNA binding	13/2581	58/18639	0.224137931034483	1.6186388595706	0.0509491433660898	0.198717051618193
GO:0061630	ubiquitin protein ligase activity	60/2581	353/18639	0.169971671388102	1.22747074118668	0.052152897776447	0.202799370570461
GO:0044390	ubiquitin-like protein conjugating enzyme binding	9/2581	36/18639	0.25	1.80540488182875	0.0526250519080589	0.202826246981055
GO:0003713	transcription coactivator activity	45/2581	256/18639	0.17578125	1.26942530753584	0.052927891182921	0.202826246981055
GO:0008514	organic anion transmembrane transporter activity	47/2581	269/18639	0.174721189591078	1.26176995458663	0.0532815192947774	0.202826246981055
GO:0097110	scaffold protein binding	15/2581	70/18639	0.214285714285714	1.54748989871036	0.0537877309043432	0.202826246981055
GO:0004954	prostanoid receptor activity	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0015205	nucleobase transmembrane transporter activity	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0016176	superoxide-generating NADPH oxidase activator activity	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0019107	myristoyltransferase activity	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0032794	GTPase activating protein binding	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0048185	activin binding	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0050786	RAGE receptor binding	4/2581	11/18639	0.363636363636364	2.62604346447818	0.0540451037656722	0.202826246981055
GO:0051018	protein kinase A binding	12/2581	53/18639	0.226415094339623	1.63508366656189	0.0554215854874037	0.206789788624966
GO:1901505	carbohydrate derivative transmembrane transporter activity	12/2581	53/18639	0.226415094339623	1.63508366656189	0.0554215854874037	0.206789788624966
GO:0008234	cysteine-type peptidase activity	34/2581	187/18639	0.181818181818182	1.31302173223909	0.0566366296272352	0.21019640758101
GO:0019894	kinesin binding	10/2581	42/18639	0.238095238095238	1.71943322078928	0.056985857980909	0.21019640758101
GO:0035198	miRNA binding	10/2581	42/18639	0.238095238095238	1.71943322078928	0.056985857980909	0.21019640758101
GO:0042056	chemoattractant activity	10/2581	42/18639	0.238095238095238	1.71943322078928	0.056985857980909	0.21019640758101
GO:0004879	nuclear receptor activity	13/2581	59/18639	0.220338983050847	1.59120430262873	0.0573927074575812	0.211093975292699
GO:0008157	protein phosphatase 1 binding	7/2581	26/18639	0.269230769230769	1.94428218043096	0.0584092234505354	0.212412133731384
GO:0052742	phosphatidylinositol kinase activity	7/2581	26/18639	0.269230769230769	1.94428218043096	0.0584092234505354	0.212412133731384
GO:0070412	R-SMAD binding	7/2581	26/18639	0.269230769230769	1.94428218043096	0.0584092234505354	0.212412133731384
GO:0097602	cullin family protein binding	7/2581	26/18639	0.269230769230769	1.94428218043096	0.0584092234505354	0.212412133731384
GO:0120013	lipid transfer activity	14/2581	65/18639	0.215384615384615	1.55542574434477	0.0588233993105324	0.212759018518157
GO:0005159	insulin-like growth factor receptor binding	5/2581	16/18639	0.3125	2.25675610228594	0.0593286186417789	0.212759018518157
GO:0015923	mannosidase activity	5/2581	16/18639	0.3125	2.25675610228594	0.0593286186417789	0.212759018518157
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2581	16/18639	0.3125	2.25675610228594	0.0593286186417789	0.212759018518157
GO:0022858	alanine transmembrane transporter activity	5/2581	16/18639	0.3125	2.25675610228594	0.0593286186417789	0.212759018518157
GO:0005123	death receptor binding	6/2581	21/18639	0.285714285714286	2.06331986494714	0.0599750560420749	0.214037090265754
GO:0005516	calmodulin binding	37/2581	207/18639	0.178743961352657	1.29082088169398	0.0600165969606528	0.214037090265754
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	25/2581	132/18639	0.189393939393939	1.36773097108239	0.0621955030792542	0.221196678995364
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	13/2581	60/18639	0.216666666666667	1.56468423091825	0.0643634682226967	0.228278124932696
GO:0005125	cytokine activity	41/2581	234/18639	0.175213675213675	1.2653264983757	0.0648237411610265	0.229280684490096
GO:0019199	transmembrane receptor protein kinase activity	16/2581	78/18639	0.205128205128205	1.48135785175692	0.066686420377277	0.235224504664111
GO:0060590	ATPase regulator activity	11/2581	49/18639	0.224489795918367	1.62117989388704	0.0683741248205705	0.240386638177261
GO:0005385	zinc ion transmembrane transporter activity	7/2581	27/18639	0.259259259259259	1.87227172930389	0.0698012666491277	0.240386638177261
GO:0004126	cytidine deaminase activity	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0015269	calcium-activated potassium channel activity	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0035497	cAMP response element binding	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0070679	inositol 1,4,5 trisphosphate binding	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0097677	STAT family protein binding	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/2581	12/18639	0.333333333333333	2.407206509105	0.0724471868506015	0.240386638177261
GO:0050840	extracellular matrix binding	14/2581	67/18639	0.208955223880597	1.5089951251106	0.072752734908287	0.240386638177261
GO:0003714	transcription corepressor activity	36/2581	204/18639	0.176470588235294	1.27440344599676	0.0730288639045033	0.240386638177261
GO:0031683	G-protein beta/gamma-subunit complex binding	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0032931	histone H3K56 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0043992	histone H3K9 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0043993	histone H3K18 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0043994	histone H3K23 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0043999	histone H2AK5 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0044012	histone H2AK9 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0044014	histone H2BK5 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0044015	histone H2BK12 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0044016	histone H3K4 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0044017	histone H3K27 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0044018	histone H3K36 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0046972	histone H4K16 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0140908	histone H3K122 acetyltransferase activity	6/2581	22/18639	0.272727272727273	1.96953259835863	0.0731773422181748	0.240386638177261
GO:0001046	core promoter sequence-specific DNA binding	10/2581	44/18639	0.227272727272727	1.64127716529886	0.0746079095185477	0.241451060843143
GO:0001223	transcription coactivator binding	10/2581	44/18639	0.227272727272727	1.64127716529886	0.0746079095185477	0.241451060843143
GO:0016790	thiolester hydrolase activity	10/2581	44/18639	0.227272727272727	1.64127716529886	0.0746079095185477	0.241451060843143
GO:0043014	alpha-tubulin binding	10/2581	44/18639	0.227272727272727	1.64127716529886	0.0746079095185477	0.241451060843143
GO:0016805	dipeptidase activity	5/2581	17/18639	0.294117647058824	2.12400574332794	0.0748105533208809	0.241451060843143
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/2581	17/18639	0.294117647058824	2.12400574332794	0.0748105533208809	0.241451060843143
GO:0046965	nuclear retinoid X receptor binding	5/2581	17/18639	0.294117647058824	2.12400574332794	0.0748105533208809	0.241451060843143
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/2581	33/18639	0.242424242424242	1.75069564298545	0.0766341990498188	0.245495659983415
GO:0030296	protein tyrosine kinase activator activity	8/2581	33/18639	0.242424242424242	1.75069564298545	0.0766341990498188	0.245495659983415
GO:0071889	14-3-3 protein binding	8/2581	33/18639	0.242424242424242	1.75069564298545	0.0766341990498188	0.245495659983415
GO:0048020	CCR chemokine receptor binding	11/2581	50/18639	0.22	1.5887562960093	0.0771745855010404	0.246614826440206
GO:0030170	pyridoxal phosphate binding	12/2581	56/18639	0.214285714285714	1.54748989871036	0.0788816253353247	0.251447353846677
GO:0036408	histone H3K14 acetyltransferase activity	7/2581	28/18639	0.25	1.80540488182875	0.0824225424724922	0.261443494673188
GO:0141052	histone H3 demethylase activity	7/2581	28/18639	0.25	1.80540488182875	0.0824225424724922	0.261443494673188
GO:0016493	C-C chemokine receptor activity	6/2581	23/18639	0.260869565217391	1.88390074625609	0.087899508380076	0.274814947781175
GO:0043274	phospholipase binding	6/2581	23/18639	0.260869565217391	1.88390074625609	0.087899508380076	0.274814947781175
GO:0044013	histone H2B acetyltransferase activity	6/2581	23/18639	0.260869565217391	1.88390074625609	0.087899508380076	0.274814947781175
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/2581	23/18639	0.260869565217391	1.88390074625609	0.087899508380076	0.274814947781175
GO:0070279	vitamin B6 binding	12/2581	57/18639	0.210526315789474	1.52034095311895	0.0879116120689537	0.274814947781175
GO:0046943	carboxylic acid transmembrane transporter activity	33/2581	188/18639	0.175531914893617	1.26762470426274	0.0879152389106315	0.274814947781175
GO:1901682	sulfur compound transmembrane transporter activity	13/2581	63/18639	0.206349206349206	1.49017545801738	0.0885368170643514	0.276089446449463
GO:0019842	vitamin binding	27/2581	150/18639	0.18	1.2998915149167	0.090133779089066	0.280392069407191
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2581	18/18639	0.277777777777778	2.00600542425417	0.0922555650342176	0.286302727065324
GO:0004177	aminopeptidase activity	9/2581	40/18639	0.225	1.62486439364587	0.092687168894453	0.286310719111224
GO:0005342	organic acid transmembrane transporter activity	33/2581	189/18639	0.174603174603175	1.26091769524548	0.0929527420130748	0.286310719111224
GO:0043560	insulin receptor substrate binding	4/2581	13/18639	0.307692307692308	2.22203677763538	0.0935887865723754	0.286310719111224
GO:0070123	transforming growth factor beta receptor activity, type III	4/2581	13/18639	0.307692307692308	2.22203677763538	0.0935887865723754	0.286310719111224
GO:0071714	icosanoid transmembrane transporter activity	4/2581	13/18639	0.307692307692308	2.22203677763538	0.0935887865723754	0.286310719111224
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/2581	13/18639	0.307692307692308	2.22203677763538	0.0935887865723754	0.286310719111224
GO:0030291	protein serine/threonine kinase inhibitor activity	10/2581	46/18639	0.217391304347826	1.56991728854674	0.0952873345403419	0.290817846079389
GO:0010484	histone H3 acetyltransferase activity	7/2581	29/18639	0.241379310344828	1.74314954107603	0.0962643252173504	0.293106707206602
GO:0005080	protein kinase C binding	11/2581	52/18639	0.211538461538462	1.52765028462433	0.0968157645385998	0.294092122398429
GO:0008028	monocarboxylic acid transmembrane transporter activity	14/2581	70/18639	0.2	1.444323905463	0.0973993534384421	0.295165229574951
GO:0019888	protein phosphatase regulator activity	20/2581	107/18639	0.186915887850467	1.34983542566635	0.0976262997897012	0.295165229574951
GO:0000287	magnesium ion binding	39/2581	230/18639	0.169565217391304	1.22453548506646	0.102846939131464	0.308597036928825
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0015295	solute:proton symporter activity	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0030552	cAMP binding	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0043998	histone H2A acetyltransferase activity	6/2581	24/18639	0.25	1.80540488182875	0.104109101532532	0.308597036928825
GO:0030165	PDZ domain binding	16/2581	83/18639	0.192771084337349	1.39211942695229	0.10422022316109	0.308597036928825
GO:0042287	MHC protein binding	9/2581	41/18639	0.219512195121951	1.58523355477646	0.104890460860968	0.309870903824964
GO:0008201	heparin binding	30/2581	172/18639	0.174418604651163	1.25958480127587	0.106096778751944	0.312719044220914
GO:0031593	polyubiquitin modification-dependent protein binding	12/2581	59/18639	0.203389830508475	1.46880397165729	0.107807941017661	0.317038842491572
GO:0016407	acetyltransferase activity	18/2581	96/18639	0.1875	1.35405366137156	0.109128566937094	0.320193136172247
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/2581	30/18639	0.233333333333333	1.6850445563735	0.111303079544851	0.322179990341709
GO:0032452	histone demethylase activity	7/2581	30/18639	0.233333333333333	1.6850445563735	0.111303079544851	0.322179990341709
GO:0035925	mRNA 3'-UTR AU-rich region binding	7/2581	30/18639	0.233333333333333	1.6850445563735	0.111303079544851	0.322179990341709
GO:0043995	histone H4K5 acetyltransferase activity	7/2581	30/18639	0.233333333333333	1.6850445563735	0.111303079544851	0.322179990341709
GO:0043996	histone H4K8 acetyltransferase activity	7/2581	30/18639	0.233333333333333	1.6850445563735	0.111303079544851	0.322179990341709
GO:0043997	histone H4K12 acetyltransferase activity	7/2581	30/18639	0.233333333333333	1.6850445563735	0.111303079544851	0.322179990341709
GO:0070003	threonine-type peptidase activity	5/2581	19/18639	0.263157894736842	1.90042619139868	0.111582031439001	0.322264882746646
GO:0004033	aldo-keto reductase (NADPH) activity	8/2581	36/18639	0.222222222222222	1.60480433940333	0.115585550279023	0.332340635657504
GO:0004190	aspartic-type endopeptidase activity	8/2581	36/18639	0.222222222222222	1.60480433940333	0.115585550279023	0.332340635657504
GO:0005545	1-phosphatidylinositol binding	4/2581	14/18639	0.285714285714286	2.06331986494714	0.117270306711706	0.333305290732145
GO:0016530	metallochaperone activity	4/2581	14/18639	0.285714285714286	2.06331986494714	0.117270306711706	0.333305290732145
GO:0034236	protein kinase A catalytic subunit binding	4/2581	14/18639	0.285714285714286	2.06331986494714	0.117270306711706	0.333305290732145
GO:0071933	Arp2/3 complex binding	4/2581	14/18639	0.285714285714286	2.06331986494714	0.117270306711706	0.333305290732145
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	4/2581	14/18639	0.285714285714286	2.06331986494714	0.117270306711706	0.333305290732145
GO:0008235	metalloexopeptidase activity	13/2581	66/18639	0.196969696969697	1.42244020992568	0.117691880568222	0.333305290732145
GO:0016829	lyase activity	34/2581	200/18639	0.17	1.22767531964355	0.117728282396482	0.333305290732145
GO:0050661	NADP binding	11/2581	54/18639	0.203703703703704	1.47107064445305	0.11917194516011	0.336654225824293
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	6/2581	25/18639	0.24	1.7331886865556	0.121752046469325	0.340220545437011
GO:0017025	TBP-class protein binding	6/2581	25/18639	0.24	1.7331886865556	0.121752046469325	0.340220545437011
GO:0019211	phosphatase activator activity	6/2581	25/18639	0.24	1.7331886865556	0.121752046469325	0.340220545437011
GO:0042974	nuclear retinoic acid receptor binding	6/2581	25/18639	0.24	1.7331886865556	0.121752046469325	0.340220545437011
GO:0047617	fatty acyl-CoA hydrolase activity	6/2581	25/18639	0.24	1.7331886865556	0.121752046469325	0.340220545437011
GO:0044325	transmembrane transporter binding	24/2581	136/18639	0.176470588235294	1.27440344599676	0.124026984493788	0.345829021558274
GO:0004521	RNA endonuclease activity	14/2581	73/18639	0.191780821917808	1.38496812852616	0.126608118233868	0.352265259999835
GO:0140457	protein demethylase activity	7/2581	31/18639	0.225806451612903	1.63068828036145	0.127501318679239	0.353987532075048
GO:0030551	cyclic nucleotide binding	8/2581	37/18639	0.216216216216216	1.56143124914919	0.130551720568748	0.36059801341852
GO:0070001	aspartic-type peptidase activity	8/2581	37/18639	0.216216216216216	1.56143124914919	0.130551720568748	0.36059801341852
GO:0048156	tau protein binding	9/2581	43/18639	0.209302325581395	1.51150176153105	0.131862284658785	0.36059801341852
GO:0001614	purinergic nucleotide receptor activity	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0001972	retinoic acid binding	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0016502	nucleotide receptor activity	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0016505	peptidase activator activity involved in apoptotic process	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0030742	GTP-dependent protein binding	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0042288	MHC class I protein binding	5/2581	20/18639	0.25	1.80540488182875	0.132675489057937	0.36059801341852
GO:0141108	transporter regulator activity	29/2581	170/18639	0.170588235294118	1.2319233311302	0.135219361264038	0.366739906285447
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/2581	26/18639	0.230769230769231	1.66652758322654	0.140754893374962	0.378572015306408
GO:0016289	acyl-CoA hydrolase activity	6/2581	26/18639	0.230769230769231	1.66652758322654	0.140754893374962	0.378572015306408
GO:0034237	protein kinase A regulatory subunit binding	6/2581	26/18639	0.230769230769231	1.66652758322654	0.140754893374962	0.378572015306408
GO:0070006	metalloaminopeptidase activity	6/2581	26/18639	0.230769230769231	1.66652758322654	0.140754893374962	0.378572015306408
GO:0004559	alpha-mannosidase activity	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0004953	icosanoid receptor activity	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0016846	carbon-sulfur lyase activity	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0031386	protein tag activity	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0050780	dopamine receptor binding	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0061578	K63-linked deubiquitinase activity	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0141047	molecular tag activity	4/2581	15/18639	0.266666666666667	1.925765207284	0.143240163906307	0.379718791792694
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/2581	32/18639	0.21875	1.57972927160015	0.144808712390985	0.383090261673692
GO:0015078	proton transmembrane transporter activity	31/2581	185/18639	0.167567567567568	1.21010921809062	0.148393531957835	0.389236006711752
GO:0005522	profilin binding	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0042975	peroxisome proliferator activated receptor binding	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0043208	glycosphingolipid binding	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0043295	glutathione binding	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0045322	unmethylated CpG binding	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:1990763	arrestin family protein binding	3/2581	10/18639	0.3	2.1664858581945	0.150749808951104	0.389236006711752
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2581	21/18639	0.238095238095238	1.71943322078928	0.155394374375394	0.398043923251258
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2581	21/18639	0.238095238095238	1.71943322078928	0.155394374375394	0.398043923251258
GO:0010314	phosphatidylinositol-5-phosphate binding	5/2581	21/18639	0.238095238095238	1.71943322078928	0.155394374375394	0.398043923251258
GO:0072542	protein phosphatase activator activity	5/2581	21/18639	0.238095238095238	1.71943322078928	0.155394374375394	0.398043923251258
GO:0004519	endonuclease activity	22/2581	127/18639	0.173228346456693	1.25098920945614	0.156280695544992	0.398731972230403
GO:0042826	histone deacetylase binding	22/2581	127/18639	0.173228346456693	1.25098920945614	0.156280695544992	0.398731972230403
GO:0140030	modification-dependent protein binding	29/2581	173/18639	0.167630057803468	1.21056049879847	0.157276061200251	0.400480069052316
GO:0001671	ATPase activator activity	6/2581	27/18639	0.222222222222222	1.60480433940333	0.161027358153772	0.409225038142755
GO:0000062	fatty-acyl-CoA binding	4/2581	16/18639	0.25	1.80540488182875	0.171210678994482	0.432549875894084
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/2581	16/18639	0.25	1.80540488182875	0.171210678994482	0.432549875894084
GO:0016722	oxidoreductase activity, acting on metal ions	4/2581	16/18639	0.25	1.80540488182875	0.171210678994482	0.432549875894084
GO:0015631	tubulin binding	60/2581	385/18639	0.155844155844156	1.12544719906208	0.177358512321183	0.447206717591109
GO:0030276	clathrin binding	9/2581	46/18639	0.195652173913043	1.41292555969206	0.178339504259442	0.448803703701638
GO:0008970	phospholipase A1 activity	5/2581	22/18639	0.227272727272727	1.64127716529886	0.179575854421635	0.449616318284937
GO:0061133	endopeptidase activator activity	5/2581	22/18639	0.227272727272727	1.64127716529886	0.179575854421635	0.449616318284937
GO:0030331	nuclear estrogen receptor binding	8/2581	40/18639	0.2	1.444323905463	0.18089899450083	0.449616318284937
GO:0032451	demethylase activity	8/2581	40/18639	0.2	1.444323905463	0.18089899450083	0.449616318284937
GO:0160215	deacylase activity	12/2581	65/18639	0.184615384615385	1.33322206658123	0.181686311725528	0.449616318284937
GO:0019789	SUMO transferase activity	6/2581	28/18639	0.214285714285714	1.54748989871036	0.182465035157757	0.449616318284937
GO:0046875	ephrin receptor binding	6/2581	28/18639	0.214285714285714	1.54748989871036	0.182465035157757	0.449616318284937
GO:0051959	dynein light intermediate chain binding	6/2581	28/18639	0.214285714285714	1.54748989871036	0.182465035157757	0.449616318284937
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/2581	28/18639	0.214285714285714	1.54748989871036	0.182465035157757	0.449616318284937
GO:0097718	disordered domain specific binding	6/2581	28/18639	0.214285714285714	1.54748989871036	0.182465035157757	0.449616318284937
GO:0016831	carboxy-lyase activity	7/2581	34/18639	0.205882352941176	1.48680402032956	0.182493377832151	0.449616318284937
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0001851	complement component C3b binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0003953	NAD+ nucleosidase activity	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0005225	volume-sensitive anion channel activity	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0008199	ferric iron binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0008271	secondary active sulfate transmembrane transporter activity	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0032050	clathrin heavy chain binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0034713	type I transforming growth factor beta receptor binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0140537	transcription regulator activator activity	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:1900750	oligopeptide binding	3/2581	11/18639	0.272727272727273	1.96953259835863	0.187014073395641	0.45043874767495
GO:0005246	calcium channel regulator activity	10/2581	53/18639	0.188679245283019	1.3625697221349	0.190899012809277	0.458939712358988
GO:1902936	phosphatidylinositol bisphosphate binding	19/2581	111/18639	0.171171171171171	1.23613307224311	0.191682972272229	0.45996787584284
GO:0043495	protein-membrane adaptor activity	9/2581	47/18639	0.191489361702128	1.38286331374117	0.195288737133766	0.466884740073504
GO:0061733	protein-lysine-acetyltransferase activity	9/2581	47/18639	0.191489361702128	1.38286331374117	0.195288737133766	0.466884740073504
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/2581	41/18639	0.195121951219512	1.40909649313463	0.199325305686251	0.471501968467536
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0015278	intracellularly gated calcium channel activity	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0019198	transmembrane receptor protein phosphatase activity	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0045125	bioactive lipid receptor activity	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0048038	quinone binding	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0070403	NAD+ binding	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:1901567	fatty acid derivative binding	4/2581	17/18639	0.235294117647059	1.69920459466235	0.200872256124822	0.471501968467536
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	11/2581	60/18639	0.183333333333333	1.32396358000775	0.201518182870104	0.47215966258676
GO:0010485	histone H4 acetyltransferase activity	7/2581	35/18639	0.2	1.444323905463	0.202718140185486	0.473253379709698
GO:0016229	steroid dehydrogenase activity	7/2581	35/18639	0.2	1.444323905463	0.202718140185486	0.473253379709698
GO:0043236	laminin binding	6/2581	29/18639	0.206896551724138	1.49412817806517	0.204952176881342	0.476952404279102
GO:0140103	catalytic activity, acting on a glycoprotein	5/2581	23/18639	0.217391304347826	1.56991728854674	0.205041506099846	0.476952404279102
GO:0051287	NAD binding	10/2581	54/18639	0.185185185185185	1.33733694950278	0.207200619093178	0.481107912318873
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/2581	67/18639	0.17910447761194	1.29342439295194	0.210612038095042	0.488151061365707
GO:0003774	cytoskeletal motor activity	25/2581	153/18639	0.163398692810458	1.18000319073774	0.214758084171264	0.496868614095165
GO:1901681	sulfur compound binding	43/2581	275/18639	0.156363636363636	1.12919868972562	0.216027347422575	0.498911101113675
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	11/2581	61/18639	0.180327868852459	1.30225925902402	0.217223708276523	0.500408122083171
GO:0004520	DNA endonuclease activity	8/2581	42/18639	0.19047619047619	1.37554657663143	0.218471177011127	0.500408122083171
GO:0098632	cell-cell adhesion mediator activity	10/2581	55/18639	0.181818181818182	1.31302173223909	0.224056401048329	0.500408122083171
GO:0003995	acyl-CoA dehydrogenase activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0004000	adenosine deaminase activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0005025	transforming growth factor beta receptor activity, type I	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0005026	transforming growth factor beta receptor activity, type II	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0005095	GTPase inhibitor activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0015132	prostaglandin transmembrane transporter activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0016361	activin receptor activity, type I	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0016362	activin receptor activity, type II	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0016801	hydrolase activity, acting on ether bonds	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0016803	ether hydrolase activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0016840	carbon-nitrogen lyase activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0017002	activin receptor activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0035197	siRNA binding	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0070410	co-SMAD binding	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:1990459	transferrin receptor binding	3/2581	12/18639	0.25	1.80540488182875	0.225203035577322	0.500408122083171
GO:0001965	G-protein alpha-subunit binding	6/2581	30/18639	0.2	1.444323905463	0.228364451215465	0.501490996648948
GO:0016769	transferase activity, transferring nitrogenous groups	6/2581	30/18639	0.2	1.444323905463	0.228364451215465	0.501490996648948
GO:0031210	phosphatidylcholine binding	6/2581	30/18639	0.2	1.444323905463	0.228364451215465	0.501490996648948
GO:0016247	channel regulator activity	27/2581	168/18639	0.160714285714286	1.16061742403277	0.229990813482575	0.501490996648948
GO:0035254	glutamate receptor binding	9/2581	49/18639	0.183673469387755	1.32641991318031	0.231087438351657	0.501490996648948
GO:0004622	lysophospholipase activity	5/2581	24/18639	0.208333333333333	1.50450406819062	0.231602665196508	0.501490996648948
GO:0030215	semaphorin receptor binding	5/2581	24/18639	0.208333333333333	1.50450406819062	0.231602665196508	0.501490996648948
GO:0050699	WW domain binding	5/2581	24/18639	0.208333333333333	1.50450406819062	0.231602665196508	0.501490996648948
GO:0070840	dynein complex binding	5/2581	24/18639	0.208333333333333	1.50450406819062	0.231602665196508	0.501490996648948
GO:0008525	phosphatidylcholine transporter activity	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:0017075	syntaxin-1 binding	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:0050811	GABA receptor binding	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:0070064	proline-rich region binding	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:1990381	ubiquitin-specific protease binding	4/2581	18/18639	0.222222222222222	1.60480433940333	0.231905596436423	0.501490996648948
GO:0002039	p53 binding	12/2581	69/18639	0.173913043478261	1.25593383083739	0.241354927062779	0.520182321933301
GO:0008080	N-acetyltransferase activity	12/2581	69/18639	0.173913043478261	1.25593383083739	0.241354927062779	0.520182321933301
GO:0070325	lipoprotein particle receptor binding	6/2581	31/18639	0.193548387096774	1.39773281173839	0.252571603024159	0.543449899173648
GO:0001848	complement binding	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0008483	transaminase activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0015645	fatty acid ligase activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0015662	P-type ion transporter activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0019707	protein-cysteine S-acyltransferase activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0120515	fatty acid-CoA ligase activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0140358	P-type transmembrane transporter activity	5/2581	25/18639	0.2	1.444323905463	0.259065319878303	0.550087710465278
GO:0005319	lipid transporter activity	28/2581	178/18639	0.157303370786517	1.13598509418438	0.261878058534142	0.551147286403125
GO:0034987	immunoglobulin receptor binding	4/2581	19/18639	0.210526315789474	1.52034095311895	0.263991880435735	0.551147286403125
GO:0120227	acyl-CoA binding	4/2581	19/18639	0.210526315789474	1.52034095311895	0.263991880435735	0.551147286403125
GO:0140036	ubiquitin-modified protein reader activity	4/2581	19/18639	0.210526315789474	1.52034095311895	0.263991880435735	0.551147286403125
GO:1990380	K48-linked deubiquitinase activity	4/2581	19/18639	0.210526315789474	1.52034095311895	0.263991880435735	0.551147286403125
GO:0005172	vascular endothelial growth factor receptor binding	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0019855	calcium channel inhibitor activity	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0046974	histone H3K9 methyltransferase activity	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0089720	caspase binding	3/2581	13/18639	0.230769230769231	1.66652758322654	0.264687310278805	0.551147286403125
GO:0004536	DNA nuclease activity	11/2581	64/18639	0.171875	1.24121585625726	0.267071470491103	0.554178749685654
GO:0005501	retinoid binding	7/2581	38/18639	0.184210526315789	1.33029833397908	0.267860216734197	0.554178749685654
GO:0019840	isoprenoid binding	7/2581	38/18639	0.184210526315789	1.33029833397908	0.267860216734197	0.554178749685654
GO:0043531	ADP binding	7/2581	38/18639	0.184210526315789	1.33029833397908	0.267860216734197	0.554178749685654
GO:0016830	carbon-carbon lyase activity	9/2581	51/18639	0.176470588235294	1.27440344599676	0.269050633855135	0.555750989291168
GO:0008194	UDP-glycosyltransferase activity	23/2581	145/18639	0.158620689655172	1.14549826984996	0.273189605076034	0.563399009829329
GO:0022884	macromolecule transmembrane transporter activity	6/2581	32/18639	0.1875	1.35405366137156	0.277439962401045	0.569916197102735
GO:0051059	NF-kappaB binding	6/2581	32/18639	0.1875	1.35405366137156	0.277439962401045	0.569916197102735
GO:0008017	microtubule binding	42/2581	276/18639	0.152173913043478	1.09894210198272	0.277674119270039	0.569916197102735
GO:0140767	enzyme-substrate adaptor activity	22/2581	139/18639	0.158273381294964	1.14299014101388	0.282565212420338	0.579034427356598
GO:0005227	calcium-activated cation channel activity	5/2581	26/18639	0.192307692307692	1.38877298602211	0.287234469045765	0.585813111434569
GO:0030247	polysaccharide binding	5/2581	26/18639	0.192307692307692	1.38877298602211	0.287234469045765	0.585813111434569
GO:0050750	low-density lipoprotein particle receptor binding	5/2581	26/18639	0.192307692307692	1.38877298602211	0.287234469045765	0.585813111434569
GO:0099106	ion channel regulator activity	25/2581	160/18639	0.15625	1.12837805114297	0.288402360587241	0.586937915755126
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	9/2581	52/18639	0.173076923076923	1.2498956874199	0.288695256781181	0.586937915755126
GO:0003823	antigen binding	27/2581	174/18639	0.155172413793103	1.12059613354888	0.291476512514648	0.59166065669247
GO:0008013	beta-catenin binding	17/2581	106/18639	0.160377358490566	1.15818426381467	0.295188648237377	0.598255172487369
GO:0070888	E-box binding	10/2581	59/18639	0.169491525423729	1.22400330971441	0.29609647812677	0.599154472196959
GO:0015095	magnesium ion transmembrane transporter activity	4/2581	20/18639	0.2	1.444323905463	0.296820978280184	0.599680568012078
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/2581	86/18639	0.162790697674419	1.17561248119081	0.299514910018816	0.60417773255358
GO:0140416	transcription regulator inhibitor activity	6/2581	33/18639	0.181818181818182	1.31302173223909	0.302834756476886	0.605562314417439
GO:0004705	JUN kinase activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0005313	L-glutamate transmembrane transporter activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0005347	ATP transmembrane transporter activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0008559	ABC-type xenobiotic transporter activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0019992	diacylglycerol binding	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0032454	histone H3K9 demethylase activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0098821	BMP receptor activity	3/2581	14/18639	0.214285714285714	1.54748989871036	0.304891947615287	0.605562314417439
GO:0043539	protein serine/threonine kinase activator activity	12/2581	73/18639	0.164383561643836	1.18711553873671	0.307243684803604	0.609295848051387
GO:0034212	protein N-acetyltransferase activity	9/2581	53/18639	0.169811320754717	1.22631274992141	0.308699033957253	0.611243025826401
GO:0015291	secondary active transmembrane transporter activity	43/2581	287/18639	0.149825783972125	1.08198480722838	0.311890184586577	0.616615969833493
GO:0004540	RNA nuclease activity	19/2581	121/18639	0.15702479338843	1.13397331420649	0.313757203898039	0.617954565471462
GO:0050997	quaternary ammonium group binding	7/2581	40/18639	0.175	1.26378341728012	0.314042336279248	0.617954565471462
GO:0001098	basal transcription machinery binding	10/2581	60/18639	0.166666666666667	1.2036032545525	0.315012137178103	0.617954565471462
GO:0001099	basal RNA polymerase II transcription machinery binding	10/2581	60/18639	0.166666666666667	1.2036032545525	0.315012137178103	0.617954565471462
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/2581	60/18639	0.166666666666667	1.2036032545525	0.315012137178103	0.617954565471462
GO:0016405	CoA-ligase activity	5/2581	27/18639	0.185185185185185	1.33733694950278	0.3159179033394	0.617954565471462
GO:0035255	ionotropic glutamate receptor binding	5/2581	27/18639	0.185185185185185	1.33733694950278	0.3159179033394	0.617954565471462
GO:0016757	glycosyltransferase activity	40/2581	267/18639	0.149812734082397	1.08189056588989	0.320031259203518	0.625053488096431
GO:0140359	ABC-type transporter activity	8/2581	47/18639	0.170212765957447	1.22921183443659	0.322464989541843	0.628855440330089
GO:0030332	cyclin binding	6/2581	34/18639	0.176470588235294	1.27440344599676	0.328622194757901	0.637004923316587
GO:0051427	hormone receptor binding	6/2581	34/18639	0.176470588235294	1.27440344599676	0.328622194757901	0.637004923316587
GO:0052866	phosphatidylinositol phosphate phosphatase activity	6/2581	34/18639	0.176470588235294	1.27440344599676	0.328622194757901	0.637004923316587
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	9/2581	54/18639	0.166666666666667	1.2036032545525	0.328998716930068	0.637004923316587
GO:0001846	opsonin binding	4/2581	21/18639	0.19047619047619	1.37554657663143	0.330097826257782	0.637004923316587
GO:0019200	carbohydrate kinase activity	4/2581	21/18639	0.19047619047619	1.37554657663143	0.330097826257782	0.637004923316587
GO:0035613	RNA stem-loop binding	4/2581	21/18639	0.19047619047619	1.37554657663143	0.330097826257782	0.637004923316587
GO:0015171	amino acid transmembrane transporter activity	16/2581	102/18639	0.156862745098039	1.13280306310823	0.335741165103736	0.646928125595408
GO:0016877	ligase activity, forming carbon-sulfur bonds	7/2581	41/18639	0.170731707317073	1.2329594314928	0.337660548460159	0.64869013104474
GO:0140318	protein transporter activity	7/2581	41/18639	0.170731707317073	1.2329594314928	0.337660548460159	0.64869013104474
GO:0000774	adenyl-nucleotide exchange factor activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0008242	omega peptidase activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0015116	sulfate transmembrane transporter activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0030553	cGMP binding	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0042809	nuclear vitamin D receptor binding	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0048531	beta-1,3-galactosyltransferase activity	3/2581	15/18639	0.2	1.444323905463	0.345304893542531	0.6546088363633
GO:0046982	protein heterodimerization activity	54/2581	369/18639	0.146341463414634	1.05682236985097	0.35158684302416	0.665540490240749
GO:0043015	gamma-tubulin binding	6/2581	35/18639	0.171428571428571	1.23799191896828	0.354671309497021	0.670396281933608
GO:0098631	cell adhesion mediator activity	12/2581	76/18639	0.157894736842105	1.14025571483921	0.359364902529146	0.678236090971434
GO:0004402	histone acetyltransferase activity	7/2581	42/18639	0.166666666666667	1.2036032545525	0.361498422749966	0.678236090971434
GO:0016859	cis-trans isomerase activity	7/2581	42/18639	0.166666666666667	1.2036032545525	0.361498422749966	0.678236090971434
GO:0008093	cytoskeletal anchor activity	4/2581	22/18639	0.181818181818182	1.31302173223909	0.363547153332481	0.678236090971434
GO:0015377	chloride:monoatomic cation symporter activity	4/2581	22/18639	0.181818181818182	1.31302173223909	0.363547153332481	0.678236090971434
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2581	22/18639	0.181818181818182	1.31302173223909	0.363547153332481	0.678236090971434
GO:0050321	tau-protein kinase activity	4/2581	22/18639	0.181818181818182	1.31302173223909	0.363547153332481	0.678236090971434
GO:0140035	ubiquitin-like protein reader activity	4/2581	22/18639	0.181818181818182	1.31302173223909	0.363547153332481	0.678236090971434
GO:0140517	protein-RNA adaptor activity	4/2581	22/18639	0.181818181818182	1.31302173223909	0.363547153332481	0.678236090971434
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/2581	29/18639	0.172413793103448	1.24510681505431	0.374091317160078	0.692900847135811
GO:0016417	S-acyltransferase activity	5/2581	29/18639	0.172413793103448	1.24510681505431	0.374091317160078	0.692900847135811
GO:0035250	UDP-galactosyltransferase activity	5/2581	29/18639	0.172413793103448	1.24510681505431	0.374091317160078	0.692900847135811
GO:0097472	cyclin-dependent protein kinase activity	5/2581	29/18639	0.172413793103448	1.24510681505431	0.374091317160078	0.692900847135811
GO:0099604	ligand-gated calcium channel activity	5/2581	29/18639	0.172413793103448	1.24510681505431	0.374091317160078	0.692900847135811
GO:0051117	ATPase binding	13/2581	84/18639	0.154761904761905	1.11763159351303	0.378400569264761	0.699878416791985
GO:0072341	modified amino acid binding	14/2581	91/18639	0.153846153846154	1.11101838881769	0.379449989025328	0.700815358843631
GO:0016409	palmitoyltransferase activity	6/2581	36/18639	0.166666666666667	1.2036032545525	0.380855542467292	0.700922960050801
GO:0004707	MAP kinase activity	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0004708	MAP kinase kinase activity	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0005521	lamin binding	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0008142	oxysterol binding	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0015562	efflux transmembrane transporter activity	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0019841	retinol binding	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0022841	potassium ion leak channel activity	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0070411	I-SMAD binding	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/2581	16/18639	0.1875	1.35405366137156	0.385480481515158	0.700922960050801
GO:0015605	organophosphate ester transmembrane transporter activity	8/2581	50/18639	0.16	1.1554591243704	0.388706736754942	0.705795213995261
GO:0005283	amino acid:sodium symporter activity	4/2581	23/18639	0.173913043478261	1.25593383083739	0.396916763276194	0.715160293049558
GO:0008171	O-methyltransferase activity	4/2581	23/18639	0.173913043478261	1.25593383083739	0.396916763276194	0.715160293049558
GO:0016849	phosphorus-oxygen lyase activity	4/2581	23/18639	0.173913043478261	1.25593383083739	0.396916763276194	0.715160293049558
GO:0022839	monoatomic ion-gated channel activity	5/2581	30/18639	0.166666666666667	1.2036032545525	0.403236690349001	0.715160293049558
GO:0008237	metallopeptidase activity	27/2581	184/18639	0.146739130434783	1.05969416976905	0.403992083410399	0.715160293049558
GO:0019213	deacetylase activity	6/2581	37/18639	0.162162162162162	1.17107343686189	0.407054077732519	0.715160293049558
GO:0042805	actinin binding	6/2581	37/18639	0.162162162162162	1.17107343686189	0.407054077732519	0.715160293049558
GO:0051082	unfolded protein binding	18/2581	121/18639	0.148760330578512	1.07429050819562	0.41029431602616	0.715160293049558
GO:0005048	signal sequence binding	8/2581	51/18639	0.156862745098039	1.13280306310823	0.410968337294441	0.715160293049558
GO:0004175	endopeptidase activity	58/2581	405/18639	0.14320987654321	1.03420724094881	0.412036202856449	0.715160293049558
GO:0001094	TFIID-class transcription factor complex binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0004382	GDP phosphatase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0005528	FK506 binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0008140	cAMP response element binding protein binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0008190	eukaryotic initiation factor 4E binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0015279	store-operated calcium channel activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0030957	Tat protein binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0031419	cobalamin binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0031434	mitogen-activated protein kinase kinase binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0035256	G protein-coupled glutamate receptor binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0043121	neurotrophin binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0050308	sugar-phosphatase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0051864	histone H3K36 demethylase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0140999	histone H3K4 trimethyltransferase activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0141109	transporter activator activity	2/2581	10/18639	0.2	1.444323905463	0.412699007220698	0.715160293049558
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2581	17/18639	0.176470588235294	1.27440344599676	0.425039386955944	0.731634464746831
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2581	17/18639	0.176470588235294	1.27440344599676	0.425039386955944	0.731634464746831
GO:0038191	neuropilin binding	3/2581	17/18639	0.176470588235294	1.27440344599676	0.425039386955944	0.731634464746831
GO:0070492	oligosaccharide binding	3/2581	17/18639	0.176470588235294	1.27440344599676	0.425039386955944	0.731634464746831
GO:1990226	histone methyltransferase binding	3/2581	17/18639	0.176470588235294	1.27440344599676	0.425039386955944	0.731634464746831
GO:0016410	N-acyltransferase activity	14/2581	94/18639	0.148936170212766	1.07556035513202	0.428666232001735	0.733224799703651
GO:0004806	triacylglycerol lipase activity	4/2581	24/18639	0.166666666666667	1.2036032545525	0.429979582892131	0.733224799703651
GO:0005315	phosphate transmembrane transporter activity	4/2581	24/18639	0.166666666666667	1.2036032545525	0.429979582892131	0.733224799703651
GO:0005540	hyaluronic acid binding	4/2581	24/18639	0.166666666666667	1.2036032545525	0.429979582892131	0.733224799703651
GO:0140033	acetylation-dependent protein binding	4/2581	24/18639	0.166666666666667	1.2036032545525	0.429979582892131	0.733224799703651
GO:0005452	solute:inorganic anion antiporter activity	5/2581	31/18639	0.161290322580645	1.16477734311532	0.432210745603778	0.733224799703651
GO:0008327	methyl-CpG binding	5/2581	31/18639	0.161290322580645	1.16477734311532	0.432210745603778	0.733224799703651
GO:0016878	acid-thiol ligase activity	5/2581	31/18639	0.161290322580645	1.16477734311532	0.432210745603778	0.733224799703651
GO:0047499	calcium-independent phospholipase A2 activity	5/2581	31/18639	0.161290322580645	1.16477734311532	0.432210745603778	0.733224799703651
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2581	31/18639	0.161290322580645	1.16477734311532	0.432210745603778	0.733224799703651
GO:0072349	modified amino acid transmembrane transporter activity	5/2581	31/18639	0.161290322580645	1.16477734311532	0.432210745603778	0.733224799703651
GO:0000146	microfilament motor activity	6/2581	38/18639	0.157894736842105	1.14025571483921	0.433152926669704	0.733858829830168
GO:0015294	solute:monoatomic cation symporter activity	17/2581	116/18639	0.146551724137931	1.05834079279616	0.440550139992045	0.74541314643477
GO:0004867	serine-type endopeptidase inhibitor activity	14/2581	95/18639	0.147368421052632	1.06423866718326	0.445105185568519	0.752134547865128
GO:0004518	nuclease activity	30/2581	209/18639	0.143540669856459	1.03659610439928	0.445897303927826	0.752488129896501
GO:0016651	oxidoreductase activity, acting on NAD(P)H	13/2581	88/18639	0.147727272727273	1.06683015744426	0.446700404194195	0.752859297408232
GO:0004864	protein phosphatase inhibitor activity	8/2581	53/18639	0.150943396226415	1.09005577770792	0.455333277149144	0.758672995275367
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	6/2581	39/18639	0.153846153846154	1.11101838881769	0.459045776706374	0.758672995275367
GO:0008378	galactosyltransferase activity	5/2581	32/18639	0.15625	1.12837805114297	0.460872001752432	0.758672995275367
GO:0015106	bicarbonate transmembrane transporter activity	5/2581	32/18639	0.15625	1.12837805114297	0.460872001752432	0.758672995275367
GO:0042910	xenobiotic transmembrane transporter activity	5/2581	32/18639	0.15625	1.12837805114297	0.460872001752432	0.758672995275367
GO:0003707	nuclear steroid receptor activity	4/2581	25/18639	0.16	1.1554591243704	0.462534680609051	0.758672995275367
GO:0005537	D-mannose binding	4/2581	25/18639	0.16	1.1554591243704	0.462534680609051	0.758672995275367
GO:0008139	nuclear localization sequence binding	4/2581	25/18639	0.16	1.1554591243704	0.462534680609051	0.758672995275367
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/2581	25/18639	0.16	1.1554591243704	0.462534680609051	0.758672995275367
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0008526	phosphatidylinositol transfer activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0015217	ADP transmembrane transporter activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0019203	carbohydrate phosphatase activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0019215	intermediate filament binding	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0180030	inositol phosphate kinase activity	2/2581	11/18639	0.181818181818182	1.31302173223909	0.462851214737376	0.758672995275367
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/2581	18/18639	0.166666666666667	1.2036032545525	0.463666145059849	0.758672995275367
GO:0008409	5'-3' exonuclease activity	3/2581	18/18639	0.166666666666667	1.2036032545525	0.463666145059849	0.758672995275367
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2581	18/18639	0.166666666666667	1.2036032545525	0.463666145059849	0.758672995275367
GO:0099602	neurotransmitter receptor regulator activity	3/2581	18/18639	0.166666666666667	1.2036032545525	0.463666145059849	0.758672995275367
GO:0044183	protein folding chaperone	11/2581	75/18639	0.146666666666667	1.0591708640062	0.468617583101413	0.765804176941676
GO:0005506	iron ion binding	22/2581	154/18639	0.142857142857143	1.03165993247357	0.472547001667518	0.771249278322081
GO:0016836	hydro-lyase activity	9/2581	61/18639	0.147540983606557	1.06548484829238	0.474171746027105	0.772923894092162
GO:0140938	histone H3 methyltransferase activity	7/2581	47/18639	0.148936170212766	1.07556035513202	0.480758415130419	0.782672274821401
GO:0015144	carbohydrate transmembrane transporter activity	6/2581	40/18639	0.15	1.08324292909725	0.484634619134691	0.787989034386506
GO:0015145	monosaccharide transmembrane transporter activity	4/2581	26/18639	0.153846153846154	1.11101838881769	0.49440744634783	0.800609572399852
GO:0015216	purine nucleotide transmembrane transporter activity	4/2581	26/18639	0.153846153846154	1.11101838881769	0.49440744634783	0.800609572399852
GO:0120014	phospholipid transfer activity	4/2581	26/18639	0.153846153846154	1.11101838881769	0.49440744634783	0.800609572399852
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0008381	mechanosensitive monoatomic ion channel activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0016918	retinal binding	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0022840	leak channel activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0022842	narrow pore channel activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0030506	ankyrin binding	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0042577	lipid phosphatase activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0042800	histone H3K4 methyltransferase activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0042834	peptidoglycan binding	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0046527	glucosyltransferase activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0046624	sphingolipid transporter activity	3/2581	19/18639	0.157894736842105	1.14025571483921	0.50110506967687	0.800609572399852
GO:0004300	enoyl-CoA hydratase activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0005247	voltage-gated chloride channel activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0005527	macrolide binding	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0008504	monoamine transmembrane transporter activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0015166	polyol transmembrane transporter activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0015368	calcium:monoatomic cation antiporter activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0016208	AMP binding	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0017166	vinculin binding	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0031543	peptidyl-proline dioxygenase activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0035251	UDP-glucosyltransferase activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0042301	phosphate ion binding	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0045295	gamma-catenin binding	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0140900	chloride:bicarbonate antiporter activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/2581	12/18639	0.166666666666667	1.2036032545525	0.510380850569387	0.800609572399852
GO:0008376	acetylgalactosaminyltransferase activity	5/2581	34/18639	0.147058823529412	1.06200287166397	0.516760308003759	0.808651585009519
GO:0090482	vitamin transmembrane transporter activity	5/2581	34/18639	0.147058823529412	1.06200287166397	0.516760308003759	0.808651585009519
GO:0019212	phosphatase inhibitor activity	8/2581	56/18639	0.142857142857143	1.03165993247357	0.520523296824414	0.813553966344211
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2581	27/18639	0.148148148148148	1.06986955960222	0.52544910600147	0.818280815256812
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	4/2581	27/18639	0.148148148148148	1.06986955960222	0.52544910600147	0.818280815256812
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/2581	27/18639	0.148148148148148	1.06986955960222	0.52544910600147	0.818280815256812
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	17/2581	122/18639	0.139344262295082	1.00629124560947	0.528767975175515	0.822457175845289
GO:0051879	Hsp90 protein binding	6/2581	42/18639	0.142857142857143	1.03165993247357	0.534552132667051	0.829873506228847
GO:0050660	flavin adenine dinucleotide binding	12/2581	86/18639	0.13953488372093	1.0076678410207	0.536015922320216	0.829873506228847
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/2581	20/18639	0.15	1.08324292909725	0.537155203452756	0.829873506228847
GO:0005326	neurotransmitter transmembrane transporter activity	3/2581	20/18639	0.15	1.08324292909725	0.537155203452756	0.829873506228847
GO:0016408	C-acyltransferase activity	3/2581	20/18639	0.15	1.08324292909725	0.537155203452756	0.829873506228847
GO:0004843	cysteine-type deubiquitinase activity	15/2581	108/18639	0.138888888888889	1.00300271212708	0.537392913406132	0.829873506228847
GO:0046906	tetrapyrrole binding	21/2581	152/18639	0.138157894736842	0.997723750484309	0.540366199829596	0.833468057323785
GO:0004623	phospholipase A2 activity	5/2581	35/18639	0.142857142857143	1.03165993247357	0.543775141088216	0.836726706966492
GO:0005343	organic acid:sodium symporter activity	5/2581	35/18639	0.142857142857143	1.03165993247357	0.543775141088216	0.836726706966492
GO:0004465	lipoprotein lipase activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0005542	folic acid binding	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0008253	5'-nucleotidase activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0019104	DNA N-glycosylase activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0030955	potassium ion binding	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0045159	myosin II binding	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0061459	L-arginine transmembrane transporter activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0071837	HMG box domain binding	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0140666	annealing activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0140852	histone ubiquitin ligase activity	2/2581	13/18639	0.153846153846154	1.11101838881769	0.555052403349493	0.841780070452663
GO:0050698	proteoglycan sulfotransferase activity	4/2581	28/18639	0.142857142857143	1.03165993247357	0.555535724264654	0.841780070452663
GO:0051119	sugar transmembrane transporter activity	4/2581	28/18639	0.142857142857143	1.03165993247357	0.555535724264654	0.841780070452663
GO:0005201	extracellular matrix structural constituent	23/2581	168/18639	0.136904761904762	0.988674101953839	0.557715991161017	0.844093018275349
GO:0048306	calcium-dependent protein binding	11/2581	80/18639	0.1375	0.992972685005812	0.559262669997618	0.845442748204829
GO:0004222	metalloendopeptidase activity	15/2581	110/18639	0.136363636363636	0.984766299179317	0.567651913714756	0.853201402678952
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2581	36/18639	0.138888888888889	1.00300271212708	0.570052495704494	0.853201402678952
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2581	36/18639	0.138888888888889	1.00300271212708	0.570052495704494	0.853201402678952
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2581	36/18639	0.138888888888889	1.00300271212708	0.570052495704494	0.853201402678952
GO:0015085	calcium ion transmembrane transporter activity	20/2581	147/18639	0.136054421768707	0.982533269022448	0.57040532622635	0.853201402678952
GO:0005010	insulin-like growth factor receptor activity	7/2581	51/18639	0.137254901960784	0.991202680219705	0.571511674200599	0.853201402678952
GO:0005021	vascular endothelial growth factor receptor activity	7/2581	51/18639	0.137254901960784	0.991202680219705	0.571511674200599	0.853201402678952
GO:0008373	sialyltransferase activity	3/2581	21/18639	0.142857142857143	1.03165993247357	0.571664766318585	0.853201402678952
GO:0015174	basic amino acid transmembrane transporter activity	3/2581	21/18639	0.142857142857143	1.03165993247357	0.571664766318585	0.853201402678952
GO:0036122	BMP binding	3/2581	21/18639	0.142857142857143	1.03165993247357	0.571664766318585	0.853201402678952
GO:0061891	calcium ion sensor activity	3/2581	21/18639	0.142857142857143	1.03165993247357	0.571664766318585	0.853201402678952
GO:0008083	growth factor activity	22/2581	162/18639	0.135802469135802	0.980713762968703	0.574103347668987	0.855851526374898
GO:0019205	nucleobase-containing compound kinase activity	6/2581	44/18639	0.136363636363636	0.984766299179317	0.582299216812551	0.86446251633126
GO:0001786	phosphatidylserine binding	8/2581	59/18639	0.135593220338983	0.979202647771525	0.582768021221641	0.86446251633126
GO:0015459	potassium channel regulator activity	8/2581	59/18639	0.135593220338983	0.979202647771525	0.582768021221641	0.86446251633126
GO:0003785	actin monomer binding	4/2581	29/18639	0.137931034482759	0.996085452043447	0.584566829401386	0.86446251633126
GO:0004181	metallocarboxypeptidase activity	4/2581	29/18639	0.137931034482759	0.996085452043447	0.584566829401386	0.86446251633126
GO:0005416	amino acid:monoatomic cation symporter activity	4/2581	29/18639	0.137931034482759	0.996085452043447	0.584566829401386	0.86446251633126
GO:0106222	lncRNA binding	4/2581	29/18639	0.137931034482759	0.996085452043447	0.584566829401386	0.86446251633126
GO:0042054	histone methyltransferase activity	9/2581	67/18639	0.134328358208955	0.970068294713955	0.59288604488847	0.868137897356645
GO:0008509	monoatomic anion transmembrane transporter activity	20/2581	149/18639	0.134228187919463	0.969344902995301	0.595990741732099	0.868137897356645
GO:0008195	phosphatidate phosphatase activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0008494	translation activator activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0032036	myosin heavy chain binding	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0042043	neurexin family protein binding	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0044548	S100 protein binding	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0046030	inositol trisphosphate phosphatase activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0098599	palmitoyl hydrolase activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0098847	sequence-specific single stranded DNA binding	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:1901474	azole transmembrane transporter activity	2/2581	14/18639	0.142857142857143	1.03165993247357	0.596745812638527	0.868137897356645
GO:0005200	structural constituent of cytoskeleton	15/2581	112/18639	0.133928571428571	0.967181186693972	0.597139002984276	0.868137897356645
GO:0019783	ubiquitin-like protein peptidase activity	17/2581	127/18639	0.133858267716535	0.966673480034291	0.599129278380599	0.870051629234368
GO:0020037	heme binding	19/2581	142/18639	0.133802816901408	0.966273035344964	0.601221312933542	0.872108668536183
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/2581	22/18639	0.136363636363636	0.984766299179317	0.604525442053233	0.873955594278527
GO:0070034	telomerase RNA binding	3/2581	22/18639	0.136363636363636	0.984766299179317	0.604525442053233	0.873955594278527
GO:0140784	metal ion sensor activity	3/2581	22/18639	0.136363636363636	0.984766299179317	0.604525442053233	0.873955594278527
GO:0015297	antiporter activity	18/2581	135/18639	0.133333333333333	0.962882603641999	0.606766938900901	0.87621489722714
GO:0015103	inorganic anion transmembrane transporter activity	22/2581	165/18639	0.133333333333333	0.962882603641999	0.610416670250925	0.878545257852712
GO:0005548	phospholipid transporter activity	9/2581	68/18639	0.132352941176471	0.955802584497573	0.611434273866374	0.878545257852712
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	9/2581	68/18639	0.132352941176471	0.955802584497573	0.611434273866374	0.878545257852712
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/2581	30/18639	0.133333333333333	0.962882603641999	0.612463773870984	0.878545257852712
GO:0015215	nucleotide transmembrane transporter activity	4/2581	30/18639	0.133333333333333	0.962882603641999	0.612463773870984	0.878545257852712
GO:0070566	adenylyltransferase activity	4/2581	30/18639	0.133333333333333	0.962882603641999	0.612463773870984	0.878545257852712
GO:0015108	chloride transmembrane transporter activity	16/2581	121/18639	0.132231404958678	0.954924896173884	0.618967112188153	0.886575623456455
GO:0017022	myosin binding	10/2581	76/18639	0.131578947368421	0.950213095699341	0.619543380212584	0.886575623456455
GO:0042162	telomeric DNA binding	5/2581	38/18639	0.131578947368421	0.950213095699341	0.620122221519116	0.886575623456455
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/2581	181/18639	0.132596685082873	0.957562810251712	0.623639029877917	0.890617242889812
GO:0016279	protein-lysine N-methyltransferase activity	9/2581	69/18639	0.130434782608696	0.941950373128043	0.629544240883397	0.891304760476392
GO:0140463	chromatin-protein adaptor activity	7/2581	54/18639	0.12962962962963	0.936135864651944	0.634336182097709	0.891304760476392
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0005523	tropomyosin binding	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0008252	nucleotidase activity	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0033130	acetylcholine receptor binding	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0051371	muscle alpha-actinin binding	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0140776	protein-containing complex destabilizing activity	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0141050	histone H3K deacetylase activity	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0141051	histone H4K deacetylase activity	2/2581	15/18639	0.133333333333333	0.962882603641999	0.635429030960988	0.891304760476392
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2581	23/18639	0.130434782608696	0.941950373128043	0.635666743869789	0.891304760476392
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/2581	23/18639	0.130434782608696	0.941950373128043	0.635666743869789	0.891304760476392
GO:0017134	fibroblast growth factor binding	3/2581	23/18639	0.130434782608696	0.941950373128043	0.635666743869789	0.891304760476392
GO:0070577	lysine-acetylated histone binding	3/2581	23/18639	0.130434782608696	0.941950373128043	0.635666743869789	0.891304760476392
GO:0016758	hexosyltransferase activity	26/2581	197/18639	0.131979695431472	0.953107145737004	0.635857230363096	0.891304760476392
GO:0017147	Wnt-protein binding	4/2581	31/18639	0.129032258064516	0.931821874492257	0.639167926206867	0.894667517901908
GO:0101005	deubiquitinase activity	15/2581	115/18639	0.130434782608696	0.941950373128043	0.639642230072395	0.894667517901908
GO:0017171	serine hydrolase activity	26/2581	198/18639	0.131313131313131	0.948293473283787	0.646429038371578	0.903181697551631
GO:0016278	lysine N-methyltransferase activity	9/2581	70/18639	0.128571428571429	0.928493939226213	0.647192046184866	0.903270196350986
GO:0015293	symporter activity	19/2581	146/18639	0.13013698630137	0.939799801499897	0.65127557436137	0.907987868791067
GO:0009055	electron transfer activity	15/2581	116/18639	0.129310344827586	0.933830111290732	0.653294654113319	0.909820278813695
GO:0045296	cadherin binding	44/2581	334/18639	0.131736526946108	0.95135107545467	0.664361388265141	0.917835310249549
GO:0042562	hormone binding	12/2581	94/18639	0.127659574468085	0.921908875827446	0.664430044940479	0.917835310249549
GO:0005179	hormone activity	17/2581	132/18639	0.128787878787879	0.930057060336022	0.664616499222257	0.917835310249549
GO:0047498	calcium-dependent phospholipase A2 activity	4/2581	32/18639	0.125	0.902702440914374	0.6646387725575	0.917835310249549
GO:0015149	hexose transmembrane transporter activity	3/2581	24/18639	0.125	0.902702440914374	0.665050624009455	0.917835310249549
GO:0055056	D-glucose transmembrane transporter activity	3/2581	24/18639	0.125	0.902702440914374	0.665050624009455	0.917835310249549
GO:0070300	phosphatidic acid binding	3/2581	24/18639	0.125	0.902702440914374	0.665050624009455	0.917835310249549
GO:0015036	disulfide oxidoreductase activity	5/2581	40/18639	0.125	0.902702440914374	0.66654926468542	0.917835310249549
GO:0071949	FAD binding	5/2581	40/18639	0.125	0.902702440914374	0.66654926468542	0.917835310249549
GO:0140662	ATP-dependent protein folding chaperone	5/2581	40/18639	0.125	0.902702440914374	0.66654926468542	0.917835310249549
GO:0016835	carbon-oxygen lyase activity	10/2581	79/18639	0.126582278481013	0.914129054090506	0.669361944018171	0.917835310249549
GO:0015378	sodium:chloride symporter activity	2/2581	16/18639	0.125	0.902702440914374	0.671135966596107	0.917835310249549
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/2581	16/18639	0.125	0.902702440914374	0.671135966596107	0.917835310249549
GO:0034450	ubiquitin-ubiquitin ligase activity	2/2581	16/18639	0.125	0.902702440914374	0.671135966596107	0.917835310249549
GO:0055102	lipase inhibitor activity	2/2581	16/18639	0.125	0.902702440914374	0.671135966596107	0.917835310249549
GO:0140327	flippase activity	2/2581	16/18639	0.125	0.902702440914374	0.671135966596107	0.917835310249549
GO:0140328	floppase activity	2/2581	16/18639	0.125	0.902702440914374	0.671135966596107	0.917835310249549
GO:0008236	serine-type peptidase activity	25/2581	194/18639	0.128865979381443	0.930621073107602	0.68255483541895	0.932463801614671
GO:0008137	NADH dehydrogenase (ubiquinone) activity	5/2581	41/18639	0.121951219512195	0.880685308209146	0.688315805043468	0.938348156611528
GO:0017080	sodium channel regulator activity	5/2581	41/18639	0.121951219512195	0.880685308209146	0.688315805043468	0.938348156611528
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/2581	57/18639	0.12280701754386	0.886865555986052	0.691549417878966	0.941761918229689
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2581	25/18639	0.12	0.866594343277799	0.692666434473146	0.94228911159624
GO:0046873	metal ion transmembrane transporter activity	59/2581	450/18639	0.131111111111111	0.946834560247966	0.696789038640963	0.946664539011424
GO:0003727	single-stranded RNA binding	11/2581	89/18639	0.123595505617978	0.892559716859156	0.703661499025949	0.946664539011424
GO:0004550	nucleoside diphosphate kinase activity	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0005092	GDP-dissociation inhibitor activity	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0016018	cyclosporin A binding	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0017110	nucleoside diphosphate phosphatase activity	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0030548	acetylcholine receptor regulator activity	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0031489	myosin V binding	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0032183	SUMO binding	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0045236	CXCR chemokine receptor binding	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0051787	misfolded protein binding	2/2581	17/18639	0.117647058823529	0.849602297331176	0.703948843881462	0.946664539011424
GO:0043175	RNA polymerase core enzyme binding	5/2581	42/18639	0.119047619047619	0.859716610394642	0.709094679688931	0.952592332443714
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/2581	34/18639	0.117647058823529	0.849602297331176	0.711797548801707	0.955229350834724
GO:0004529	DNA exonuclease activity	3/2581	26/18639	0.115384615384615	0.833263791613269	0.718526302489492	0.961261612967807
GO:0005112	Notch binding	3/2581	26/18639	0.115384615384615	0.833263791613269	0.718526302489492	0.961261612967807
GO:0030507	spectrin binding	3/2581	26/18639	0.115384615384615	0.833263791613269	0.718526302489492	0.961261612967807
GO:0070063	RNA polymerase binding	7/2581	59/18639	0.11864406779661	0.856802316800084	0.726301724885349	0.97065789526603
GO:0140566	histone reader activity	4/2581	35/18639	0.114285714285714	0.825327945978856	0.733477859474416	0.972108145178497
GO:0003746	translation elongation factor activity	2/2581	18/18639	0.111111111111111	0.802402169701666	0.733984181234164	0.972108145178497
GO:0008308	voltage-gated monoatomic anion channel activity	2/2581	18/18639	0.111111111111111	0.802402169701666	0.733984181234164	0.972108145178497
GO:0015373	monoatomic anion:sodium symporter activity	2/2581	18/18639	0.111111111111111	0.802402169701666	0.733984181234164	0.972108145178497
GO:0031690	adrenergic receptor binding	2/2581	18/18639	0.111111111111111	0.802402169701666	0.733984181234164	0.972108145178497
GO:0098641	cadherin binding involved in cell-cell adhesion	2/2581	18/18639	0.111111111111111	0.802402169701666	0.733984181234164	0.972108145178497
GO:1901611	phosphatidylglycerol binding	2/2581	18/18639	0.111111111111111	0.802402169701666	0.733984181234164	0.972108145178497
GO:0003777	microtubule motor activity	8/2581	68/18639	0.117647058823529	0.849602297331176	0.742145582639455	0.972108145178497
GO:0140034	methylation-dependent protein binding	9/2581	76/18639	0.118421052631579	0.855191786129407	0.742447364332203	0.972108145178497
GO:0008266	poly(U) RNA binding	3/2581	27/18639	0.111111111111111	0.802402169701666	0.742660952050495	0.972108145178497
GO:0008320	protein transmembrane transporter activity	3/2581	27/18639	0.111111111111111	0.802402169701666	0.742660952050495	0.972108145178497
GO:0015252	proton channel activity	3/2581	27/18639	0.111111111111111	0.802402169701666	0.742660952050495	0.972108145178497
GO:0005262	calcium channel activity	16/2581	131/18639	0.122137404580153	0.882029865931602	0.743159641711183	0.972108145178497
GO:0003954	NADH dehydrogenase activity	5/2581	44/18639	0.113636363636364	0.820638582649431	0.747671964057694	0.972108145178497
GO:0030547	signaling receptor inhibitor activity	5/2581	44/18639	0.113636363636364	0.820638582649431	0.747671964057694	0.972108145178497
GO:0000993	RNA polymerase II complex binding	4/2581	36/18639	0.111111111111111	0.802402169701666	0.753906029945656	0.972108145178497
GO:0005003	ephrin receptor activity	6/2581	53/18639	0.113207547169811	0.817541833280943	0.760906762986495	0.972108145178497
GO:0005005	transmembrane-ephrin receptor activity	6/2581	53/18639	0.113207547169811	0.817541833280943	0.760906762986495	0.972108145178497
GO:0008146	sulfotransferase activity	6/2581	53/18639	0.113207547169811	0.817541833280943	0.760906762986495	0.972108145178497
GO:0017046	peptide hormone binding	6/2581	53/18639	0.113207547169811	0.817541833280943	0.760906762986495	0.972108145178497
GO:0038064	collagen receptor activity	6/2581	53/18639	0.113207547169811	0.817541833280943	0.760906762986495	0.972108145178497
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0005229	intracellularly calcium-gated chloride channel activity	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0005520	insulin-like growth factor binding	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0008301	DNA binding, bending	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0008574	plus-end-directed microtubule motor activity	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0031420	alkali metal ion binding	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0141147	intracellularly calcium-gated channel activity	2/2581	19/18639	0.105263157894737	0.760170476559473	0.761381723770315	0.972108145178497
GO:0045499	chemorepellent activity	3/2581	28/18639	0.107142857142857	0.773744949355178	0.765115979384795	0.972108145178497
GO:0051393	alpha-actinin binding	3/2581	28/18639	0.107142857142857	0.773744949355178	0.765115979384795	0.972108145178497
GO:0016853	isomerase activity	22/2581	180/18639	0.122222222222222	0.882642386671833	0.767648914595338	0.972108145178497
GO:0000182	rDNA binding	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0003796	lysozyme activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0005337	nucleoside transmembrane transporter activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0008401	retinoic acid 4-hydroxylase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0015187	glycine transmembrane transporter activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0015203	polyamine transmembrane transporter activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0015643	toxic substance binding	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0016783	sulfurtransferase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0016868	intramolecular phosphotransferase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0019531	oxalate transmembrane transporter activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0019911	structural constituent of myelin sheath	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0032052	bile acid binding	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0051880	G-quadruplex DNA binding	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0070739	protein-glutamic acid ligase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0070740	tubulin-glutamic acid ligase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0098505	G-rich strand telomeric DNA binding	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0140940	histone H2A methyltransferase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:1990259	histone H2AQ104 methyltransferase activity	1/2581	10/18639	0.1	0.722161952731499	0.774825159867292	0.972108145178497
GO:0008276	protein methyltransferase activity	11/2581	95/18639	0.115789473684211	0.83618752421542	0.781494129959089	0.97798413318134
GO:0005253	monoatomic anion channel activity	12/2581	103/18639	0.116504854368932	0.841353731337669	0.781556886829222	0.97798413318134
GO:0015370	solute:sodium symporter activity	9/2581	79/18639	0.113924050632911	0.822716148681455	0.782861306705434	0.97798413318134
GO:0000339	RNA cap binding	2/2581	20/18639	0.1	0.722161952731499	0.786295781583378	0.97798413318134
GO:0043024	ribosomal small subunit binding	2/2581	20/18639	0.1	0.722161952731499	0.786295781583378	0.97798413318134
GO:0052745	inositol phosphate phosphatase activity	2/2581	20/18639	0.1	0.722161952731499	0.786295781583378	0.97798413318134
GO:0061608	nuclear import signal receptor activity	2/2581	20/18639	0.1	0.722161952731499	0.786295781583378	0.97798413318134
GO:0005109	frizzled binding	4/2581	38/18639	0.105263157894737	0.760170476559473	0.791102097227408	0.97798413318134
GO:0008187	poly-pyrimidine tract binding	3/2581	30/18639	0.1	0.722161952731499	0.805224662473947	0.97798413318134
GO:0048019	receptor antagonist activity	3/2581	30/18639	0.1	0.722161952731499	0.805224662473947	0.97798413318134
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0002162	dystroglycan binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0004016	adenylate cyclase activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0005536	D-glucose binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0008046	axon guidance receptor activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0008172	S-methyltransferase activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0008503	benzodiazepine receptor activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0010854	adenylate cyclase regulator activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0019206	nucleoside kinase activity	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0031731	CCR6 chemokine receptor binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0032404	mismatch repair complex binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0034056	estrogen response element binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0043522	leucine zipper domain binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0045294	alpha-catenin binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0048407	platelet-derived growth factor binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0050998	nitric-oxide synthase binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0070697	activin receptor binding	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2581	11/18639	0.0909090909090909	0.656510866119545	0.806022554380283	0.97798413318134
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/2581	39/18639	0.102564102564103	0.740678925878461	0.807935487311503	0.978323891311533
GO:0015125	bile acid transmembrane transporter activity	2/2581	21/18639	0.0952380952380952	0.687773288315714	0.808888520032303	0.978323891311533
GO:0035064	methylated histone binding	8/2581	74/18639	0.108108108108108	0.780715624574594	0.821701013112875	0.978323891311533
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/2581	31/18639	0.0967741935483871	0.698866405869193	0.823016455645419	0.978323891311533
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/2581	40/18639	0.1	0.722161952731499	0.82364506760329	0.978323891311533
GO:0071855	neuropeptide receptor binding	4/2581	40/18639	0.1	0.722161952731499	0.82364506760329	0.978323891311533
GO:0005004	GPI-linked ephrin receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0005008	hepatocyte growth factor receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0005009	insulin receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0005011	macrophage colony-stimulating factor receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0005020	stem cell factor receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0008288	boss receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0036332	placental growth factor receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0038062	protein tyrosine kinase collagen receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0060175	brain-derived neurotrophic factor receptor activity	5/2581	49/18639	0.102040816326531	0.736899951766836	0.82721836504588	0.978323891311533
GO:0005254	chloride channel activity	9/2581	83/18639	0.108433734939759	0.783067177660662	0.829277251148703	0.978323891311533
GO:0004407	histone deacetylase activity	2/2581	22/18639	0.0909090909090909	0.656510866119545	0.82932482783021	0.978323891311533
GO:0005243	gap junction channel activity	2/2581	22/18639	0.0909090909090909	0.656510866119545	0.82932482783021	0.978323891311533
GO:0016881	acid-amino acid ligase activity	2/2581	22/18639	0.0909090909090909	0.656510866119545	0.82932482783021	0.978323891311533
GO:0033558	protein lysine deacetylase activity	2/2581	22/18639	0.0909090909090909	0.656510866119545	0.82932482783021	0.978323891311533
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	6/2581	58/18639	0.103448275862069	0.747064089032586	0.832155292276424	0.978323891311533
GO:0000340	RNA 7-methylguanosine cap binding	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0004032	aldose reductase (NADPH) activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0004859	phospholipase inhibitor activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0005049	nuclear export signal receptor activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0005165	neurotrophin receptor binding	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0005436	sodium:phosphate symporter activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0016273	arginine N-methyltransferase activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0016274	protein-arginine N-methyltransferase activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0036009	protein-glutamine N-methyltransferase activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0043047	single-stranded telomeric DNA binding	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2581	12/18639	0.0833333333333333	0.60180162727625	0.832899072908547	0.978323891311533
GO:0016500	protein-hormone receptor activity	7/2581	67/18639	0.104477611940299	0.754497562555298	0.837722140880313	0.978323891311533
GO:0140828	metal cation:monoatomic cation antiporter activity	4/2581	41/18639	0.0975609756097561	0.704548246567317	0.838275258150297	0.978323891311533
GO:0031369	translation initiation factor binding	3/2581	32/18639	0.09375	0.677026830685781	0.839400353895894	0.978323891311533
GO:0070717	poly-purine tract binding	3/2581	32/18639	0.09375	0.677026830685781	0.839400353895894	0.978323891311533
GO:0140142	nucleocytoplasmic carrier activity	3/2581	32/18639	0.09375	0.677026830685781	0.839400353895894	0.978323891311533
GO:0180051	translation factor activity	9/2581	84/18639	0.107142857142857	0.773744949355178	0.839593917459104	0.978323891311533
GO:0005006	epidermal growth factor receptor activity	5/2581	50/18639	0.1	0.722161952731499	0.840403714534849	0.978323891311533
GO:0005007	fibroblast growth factor receptor activity	5/2581	50/18639	0.1	0.722161952731499	0.840403714534849	0.978323891311533
GO:0005017	platelet-derived growth factor receptor activity	5/2581	50/18639	0.1	0.722161952731499	0.840403714534849	0.978323891311533
GO:0005019	platelet-derived growth factor beta-receptor activity	5/2581	50/18639	0.1	0.722161952731499	0.840403714534849	0.978323891311533
GO:0003887	DNA-directed DNA polymerase activity	2/2581	23/18639	0.0869565217391304	0.627966915418695	0.847768454874059	0.979755650701828
GO:0005212	structural constituent of eye lens	2/2581	23/18639	0.0869565217391304	0.627966915418695	0.847768454874059	0.979755650701828
GO:0031681	G-protein beta-subunit binding	2/2581	23/18639	0.0869565217391304	0.627966915418695	0.847768454874059	0.979755650701828
GO:0005030	neurotrophin receptor activity	5/2581	51/18639	0.0980392156862745	0.708001914442646	0.852749550277286	0.979755650701828
GO:0016597	amino acid binding	5/2581	51/18639	0.0980392156862745	0.708001914442646	0.852749550277286	0.979755650701828
GO:0004535	poly(A)-specific ribonuclease activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0008417	fucosyltransferase activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0031432	titin binding	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0031994	insulin-like growth factor I binding	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0039706	co-receptor binding	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0046975	histone H3K36 methyltransferase activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0051011	microtubule minus-end binding	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0070700	BMP receptor binding	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0097157	pre-mRNA intronic binding	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0140333	glycerophospholipid flippase activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2581	13/18639	0.0769230769230769	0.555509194408846	0.856052962038468	0.979755650701828
GO:0048027	mRNA 5'-UTR binding	2/2581	24/18639	0.0833333333333333	0.60180162727625	0.864379166770842	0.986785087599227
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2581	24/18639	0.0833333333333333	0.60180162727625	0.864379166770842	0.986785087599227
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2581	43/18639	0.0930232558139535	0.671778560680465	0.864487942737975	0.986785087599227
GO:0016782	transferase activity, transferring sulphur-containing groups	7/2581	70/18639	0.1	0.722161952731499	0.86882756407504	0.990862531113849
GO:0005544	calcium-dependent phospholipid binding	5/2581	53/18639	0.0943396226415094	0.681284861067452	0.875058588316415	0.992031200524084
GO:0005344	oxygen carrier activity	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:0008392	arachidonate epoxygenase activity	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:0015926	glucosidase activity	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:0031404	chloride ion binding	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:0043176	amine binding	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:0061783	peptidoglycan muralytic activity	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:1901612	cardiolipin binding	1/2581	14/18639	0.0714285714285714	0.515829966236785	0.875999665838463	0.992031200524084
GO:0005251	delayed rectifier potassium channel activity	2/2581	25/18639	0.08	0.5777295621852	0.879310708709772	0.99403688699152
GO:0015271	outward rectifier potassium channel activity	2/2581	25/18639	0.08	0.5777295621852	0.879310708709772	0.99403688699152
GO:0140303	intramembrane lipid transporter activity	4/2581	45/18639	0.0888888888888889	0.641921735761333	0.886968531581289	1
GO:0008170	N-methyltransferase activity	10/2581	98/18639	0.102040816326531	0.736899951766836	0.88744385335646	1
GO:0005267	potassium channel activity	13/2581	124/18639	0.104838709677419	0.757105273024959	0.892036209829279	1
GO:0045505	dynein intermediate chain binding	3/2581	36/18639	0.0833333333333333	0.60180162727625	0.892441269372455	1
GO:0051139	metal cation:proton antiporter activity	2/2581	26/18639	0.0769230769230769	0.555509194408846	0.892709409228129	1
GO:0004129	cytochrome-c oxidase activity	1/2581	15/18639	0.0666666666666667	0.481441301821	0.893183282615426	1
GO:0010181	FMN binding	1/2581	15/18639	0.0666666666666667	0.481441301821	0.893183282615426	1
GO:0015250	water channel activity	1/2581	15/18639	0.0666666666666667	0.481441301821	0.893183282615426	1
GO:0034483	heparan sulfate sulfotransferase activity	1/2581	15/18639	0.0666666666666667	0.481441301821	0.893183282615426	1
GO:0140161	monocarboxylate:sodium symporter activity	1/2581	15/18639	0.0666666666666667	0.481441301821	0.893183282615426	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/2581	46/18639	0.0869565217391304	0.627966915418695	0.896935308793475	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	4/2581	46/18639	0.0869565217391304	0.627966915418695	0.896935308793475	1
GO:0003684	damaged DNA binding	7/2581	74/18639	0.0945945945945946	0.68312617150277	0.902488069975066	1
GO:0022829	wide pore channel activity	3/2581	37/18639	0.0810810810810811	0.585536718430946	0.902971009413503	1
GO:0008135	translation factor activity, RNA binding	8/2581	83/18639	0.0963855421686747	0.696059713476144	0.90367914001609	1
GO:0008395	steroid hydroxylase activity	2/2581	27/18639	0.0740740740740741	0.534934779801111	0.904713285802339	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2581	16/18639	0.0625	0.451351220457187	0.907986437016714	1
GO:0008296	3'-5'-DNA exonuclease activity	1/2581	16/18639	0.0625	0.451351220457187	0.907986437016714	1
GO:0008391	arachidonate monooxygenase activity	1/2581	16/18639	0.0625	0.451351220457187	0.907986437016714	1
GO:0030275	LRR domain binding	1/2581	16/18639	0.0625	0.451351220457187	0.907986437016714	1
GO:0043023	ribosomal large subunit binding	1/2581	16/18639	0.0625	0.451351220457187	0.907986437016714	1
GO:0097027	ubiquitin-protein transferase activator activity	1/2581	16/18639	0.0625	0.451351220457187	0.907986437016714	1
GO:0016779	nucleotidyltransferase activity	14/2581	136/18639	0.102941176470588	0.743402010164779	0.912545781275124	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/2581	48/18639	0.0833333333333333	0.60180162727625	0.914570404793073	1
GO:0005242	inward rectifier potassium channel activity	2/2581	28/18639	0.0714285714285714	0.515829966236785	0.91545154014215	1
GO:0008527	taste receptor activity	2/2581	28/18639	0.0714285714285714	0.515829966236785	0.91545154014215	1
GO:0051537	2 iron, 2 sulfur cluster binding	2/2581	28/18639	0.0714285714285714	0.515829966236785	0.91545154014215	1
GO:0004549	tRNA-specific ribonuclease activity	1/2581	17/18639	0.0588235294117647	0.424801148665588	0.920738786587667	1
GO:0004659	prenyltransferase activity	1/2581	17/18639	0.0588235294117647	0.424801148665588	0.920738786587667	1
GO:0008569	minus-end-directed microtubule motor activity	1/2581	17/18639	0.0588235294117647	0.424801148665588	0.920738786587667	1
GO:0070402	NADPH binding	1/2581	17/18639	0.0588235294117647	0.424801148665588	0.920738786587667	1
GO:0000217	DNA secondary structure binding	3/2581	39/18639	0.0769230769230769	0.555509194408846	0.921278463815474	1
GO:0036002	pre-mRNA binding	5/2581	59/18639	0.0847457627118644	0.612001654857203	0.92548710297372	1
GO:0042393	histone binding	27/2581	247/18639	0.109311740890688	0.789407802580991	0.927144022317545	1
GO:0004532	RNA exonuclease activity	3/2581	40/18639	0.075	0.541621464548625	0.929194685129976	1
GO:0000400	four-way junction DNA binding	1/2581	18/18639	0.0555555555555556	0.401201084850833	0.931724351608461	1
GO:0005372	water transmembrane transporter activity	1/2581	18/18639	0.0555555555555556	0.401201084850833	0.931724351608461	1
GO:0015280	ligand-gated sodium channel activity	1/2581	18/18639	0.0555555555555556	0.401201084850833	0.931724351608461	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2581	18/18639	0.0555555555555556	0.401201084850833	0.931724351608461	1
GO:0070628	proteasome binding	1/2581	18/18639	0.0555555555555556	0.401201084850833	0.931724351608461	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/2581	60/18639	0.0833333333333333	0.60180162727625	0.931857098086413	1
GO:0033612	receptor serine/threonine kinase binding	2/2581	30/18639	0.0666666666666667	0.481441301821	0.93360290176357	1
GO:0004497	monooxygenase activity	10/2581	106/18639	0.0943396226415094	0.681284861067452	0.934301475765271	1
GO:0003743	translation initiation factor activity	4/2581	51/18639	0.0784313725490196	0.566401531554117	0.935987998557926	1
GO:0004252	serine-type endopeptidase activity	18/2581	176/18639	0.102272727272727	0.738574724384488	0.938975283810473	1
GO:0140299	molecular sensor activity	6/2581	71/18639	0.0845070422535211	0.610277706533661	0.940524191053726	1
GO:0003756	protein disulfide isomerase activity	1/2581	19/18639	0.0526315789473684	0.380085238279737	0.941187830932803	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2581	19/18639	0.0526315789473684	0.380085238279737	0.941187830932803	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/2581	19/18639	0.0526315789473684	0.380085238279737	0.941187830932803	1
GO:0050145	nucleoside monophosphate kinase activity	1/2581	19/18639	0.0526315789473684	0.380085238279737	0.941187830932803	1
GO:0015079	potassium ion transmembrane transporter activity	16/2581	160/18639	0.1	0.722161952731499	0.942290798932931	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	4/2581	53/18639	0.0754716981132075	0.545027888853962	0.94742444338963	1
GO:0016860	intramolecular oxidoreductase activity	4/2581	53/18639	0.0754716981132075	0.545027888853962	0.94742444338963	1
GO:0099094	ligand-gated monoatomic cation channel activity	13/2581	136/18639	0.0955882352941176	0.69030186658158	0.948711146751165	1
GO:0010851	cyclase regulator activity	1/2581	20/18639	0.05	0.36108097636575	0.949340044056457	1
GO:0140939	histone H4 methyltransferase activity	1/2581	20/18639	0.05	0.36108097636575	0.949340044056457	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/2581	44/18639	0.0681818181818182	0.492383149589659	0.954062184975842	1
GO:0031491	nucleosome binding	6/2581	74/18639	0.0810810810810811	0.585536718430946	0.954133191528367	1
GO:0005248	voltage-gated sodium channel activity	1/2581	21/18639	0.0476190476190476	0.343886644157857	0.956362620257664	1
GO:0009975	cyclase activity	1/2581	21/18639	0.0476190476190476	0.343886644157857	0.956362620257664	1
GO:0051428	peptide hormone receptor binding	1/2581	21/18639	0.0476190476190476	0.343886644157857	0.956362620257664	1
GO:0070182	DNA polymerase binding	1/2581	21/18639	0.0476190476190476	0.343886644157857	0.956362620257664	1
GO:0003697	single-stranded DNA binding	11/2581	121/18639	0.0909090909090909	0.656510866119545	0.957322175707148	1
GO:0043022	ribosome binding	10/2581	112/18639	0.0892857142857143	0.644787457795982	0.957338995031236	1
GO:0051539	4 iron, 4 sulfur cluster binding	3/2581	45/18639	0.0666666666666667	0.481441301821	0.958854588789739	1
GO:0015035	protein-disulfide reductase activity	2/2581	34/18639	0.0588235294117647	0.424801148665588	0.959416595010773	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/2581	34/18639	0.0588235294117647	0.424801148665588	0.959416595010773	1
GO:0019825	oxygen binding	2/2581	34/18639	0.0588235294117647	0.424801148665588	0.959416595010773	1
GO:0034061	DNA polymerase activity	2/2581	35/18639	0.0571428571428571	0.412663972989428	0.964175378581917	1
GO:0043021	ribonucleoprotein complex binding	17/2581	177/18639	0.096045197740113	0.69360187550483	0.965351394700769	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/2581	36/18639	0.0555555555555556	0.401201084850833	0.968395032064827	1
GO:0055106	ubiquitin-protein transferase regulator activity	2/2581	36/18639	0.0555555555555556	0.401201084850833	0.968395032064827	1
GO:0005249	voltage-gated potassium channel activity	8/2581	98/18639	0.0816326530612245	0.589519961413469	0.969968711542773	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/2581	48/18639	0.0625	0.451351220457187	0.970564259493187	1
GO:0015081	sodium ion transmembrane transporter activity	15/2581	164/18639	0.0914634146341463	0.660513981156859	0.974218253150048	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/2581	38/18639	0.0526315789473684	0.380085238279737	0.975443201774332	1
GO:0017056	structural constituent of nuclear pore	1/2581	25/18639	0.04	0.2888647810926	0.975978697643373	1
GO:0005272	sodium channel activity	3/2581	51/18639	0.0588235294117647	0.424801148665588	0.979068254422334	1
GO:0008143	poly(A) binding	1/2581	26/18639	0.0384615384615385	0.277754597204423	0.979309469179983	1
GO:0004527	exonuclease activity	6/2581	84/18639	0.0714285714285714	0.515829966236785	0.981566792553037	1
GO:0005104	fibroblast growth factor receptor binding	1/2581	27/18639	0.037037037037037	0.267467389900555	0.982178553156046	1
GO:0016866	intramolecular transferase activity	1/2581	28/18639	0.0357142857142857	0.257914983118393	0.984649924008412	1
GO:0019843	rRNA binding	4/2581	65/18639	0.0615384615384615	0.444407355527077	0.984837749252908	1
GO:0008307	structural constituent of muscle	2/2581	42/18639	0.0476190476190476	0.343886644157857	0.985264415805154	1
GO:0031492	nucleosomal DNA binding	2/2581	42/18639	0.0476190476190476	0.343886644157857	0.985264415805154	1
GO:0051536	iron-sulfur cluster binding	5/2581	76/18639	0.0657894736842105	0.475106547849671	0.985284417618859	1
GO:0004386	helicase activity	13/2581	155/18639	0.0838709677419355	0.605684218419967	0.986543085841071	1
GO:0003724	RNA helicase activity	5/2581	77/18639	0.0649350649350649	0.468936332942532	0.986702683915564	1
GO:0051540	metal cluster binding	5/2581	77/18639	0.0649350649350649	0.468936332942532	0.986702683915564	1
GO:0005245	voltage-gated calcium channel activity	2/2581	43/18639	0.0465116279069767	0.335889280340232	0.987045542290298	1
GO:0022832	voltage-gated channel activity	15/2581	175/18639	0.0857142857142857	0.618995959484142	0.988019014515692	1
GO:0016887	ATP hydrolysis activity	43/2581	417/18639	0.103117505995204	0.744675394902985	0.988022209073321	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	14/2581	167/18639	0.0838323353293413	0.60540522983479	0.989031188041749	1
GO:0140223	general transcription initiation factor activity	4/2581	68/18639	0.0588235294117647	0.424801148665588	0.989046203164928	1
GO:0008186	ATP-dependent activity, acting on RNA	5/2581	79/18639	0.0632911392405063	0.457064527045253	0.989160593521546	1
GO:0140658	ATP-dependent chromatin remodeler activity	13/2581	158/18639	0.0822784810126582	0.594183885158829	0.989276094914123	1
GO:0005184	neuropeptide hormone activity	1/2581	31/18639	0.032258064516129	0.232955468623064	0.9901917687503	1
GO:0030515	snoRNA binding	1/2581	32/18639	0.03125	0.225675610228594	0.991552207532301	1
GO:0160041	neuropeptide activity	1/2581	32/18639	0.03125	0.225675610228594	0.991552207532301	1
GO:0022843	voltage-gated monoatomic cation channel activity	11/2581	143/18639	0.0769230769230769	0.555509194408846	0.992181130523077	1
GO:0061749	forked DNA-dependent helicase activity	2/2581	47/18639	0.0425531914893617	0.307302958609149	0.992293359806122	1
GO:0099095	ligand-gated monoatomic anion channel activity	2/2581	47/18639	0.0425531914893617	0.307302958609149	0.992293359806122	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	2/2581	47/18639	0.0425531914893617	0.307302958609149	0.992293359806122	1
GO:0042923	neuropeptide binding	1/2581	33/18639	0.0303030303030303	0.218836955373182	0.992724011281381	1
GO:0005244	voltage-gated monoatomic ion channel activity	14/2581	173/18639	0.0809248554913295	0.584408516661329	0.993029016101888	1
GO:0009378	four-way junction helicase activity	2/2581	48/18639	0.0416666666666667	0.300900813638125	0.993238103297988	1
GO:0036121	double-stranded DNA helicase activity	2/2581	48/18639	0.0416666666666667	0.300900813638125	0.993238103297988	1
GO:0043138	3'-5' DNA helicase activity	2/2581	48/18639	0.0416666666666667	0.300900813638125	0.993238103297988	1
GO:0015020	glucuronosyltransferase activity	1/2581	34/18639	0.0294117647058824	0.212400574332794	0.993733326925945	1
GO:0140097	catalytic activity, acting on DNA	32/2581	336/18639	0.0952380952380952	0.687773288315714	0.993788503778498	1
GO:0000175	3'-5'-RNA exonuclease activity	1/2581	35/18639	0.0285714285714286	0.206331986494714	0.994602678347828	1
GO:0015276	ligand-gated monoatomic ion channel activity	15/2581	186/18639	0.0806451612903226	0.582388671557661	0.994706909658148	1
GO:0022834	ligand-gated channel activity	15/2581	188/18639	0.0797872340425532	0.576193047392154	0.995460432887182	1
GO:0005216	monoatomic ion channel activity	44/2581	448/18639	0.0982142857142857	0.70926620357558	0.996215566686335	1
GO:0140674	ATP-dependent histone chaperone activity	11/2581	152/18639	0.0723684210526316	0.522617202634638	0.996341625170586	1
GO:0061775	cohesin loader activity	11/2581	153/18639	0.0718954248366013	0.519201403924607	0.996644588215116	1
GO:0140104	molecular carrier activity	21/2581	249/18639	0.0843373493975904	0.609052249291626	0.996895151868255	1
GO:0005261	monoatomic cation channel activity	31/2581	341/18639	0.0909090909090909	0.656510866119545	0.99727754068729	1
GO:0003730	mRNA 3'-UTR binding	22/2581	262/18639	0.083969465648855	0.606395532827977	0.997627048584536	1
GO:0016874	ligase activity	12/2581	167/18639	0.0718562874251497	0.51891876842982	0.997638123425376	1
GO:0008227	G protein-coupled amine receptor activity	1/2581	41/18639	0.024390243902439	0.176137061641829	0.997797342890911	1
GO:0008408	3'-5' exonuclease activity	2/2581	58/18639	0.0344827586206897	0.249021363010862	0.998202944787669	1
GO:0017116	single-stranded DNA helicase activity	2/2581	58/18639	0.0344827586206897	0.249021363010862	0.998202944787669	1
GO:0000510	H3-H4 histone complex chaperone activity	10/2581	151/18639	0.0662251655629139	0.478252948828808	0.998376786197934	1
GO:0140584	chromatin extrusion motor activity	10/2581	151/18639	0.0662251655629139	0.478252948828808	0.998376786197934	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	10/2581	151/18639	0.0662251655629139	0.478252948828808	0.998376786197934	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	10/2581	151/18639	0.0662251655629139	0.478252948828808	0.998376786197934	1
GO:0015616	DNA translocase activity	10/2581	152/18639	0.0657894736842105	0.475106547849671	0.998520107397043	1
GO:0003678	DNA helicase activity	3/2581	74/18639	0.0405405405405405	0.292768359215473	0.998680015526549	1
GO:0140713	histone chaperone activity	11/2581	164/18639	0.0670731707317073	0.48437691951503	0.998735537603541	1
GO:0008168	methyltransferase activity	15/2581	204/18639	0.0735294117647059	0.531001435831985	0.998737488792244	1
GO:0022836	gated channel activity	27/2581	318/18639	0.0849056603773585	0.613156374960707	0.998830745803805	1
GO:0008094	ATP-dependent activity, acting on DNA	15/2581	210/18639	0.0714285714285714	0.515829966236785	0.99923559439442	1
GO:0003689	DNA clamp loader activity	10/2581	160/18639	0.0625	0.451351220457187	0.999302486442949	1
GO:0000049	tRNA binding	3/2581	80/18639	0.0375	0.270810732274312	0.999378562684344	1
GO:0016741	transferase activity, transferring one-carbon groups	15/2581	215/18639	0.0697674418604651	0.503833920510348	0.999501033602665	1
GO:0140597	protein carrier chaperone	12/2581	188/18639	0.0638297872340425	0.460954437913723	0.999639406867215	1
GO:0017069	snRNA binding	1/2581	54/18639	0.0185185185185185	0.133733694950278	0.999684392464551	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/2581	73/18639	0.0273972602739726	0.197852589789452	0.999764768761388	1
GO:0001653	peptide receptor activity	6/2581	128/18639	0.046875	0.33851341534289	0.999814526262287	1
GO:0008528	G protein-coupled peptide receptor activity	5/2581	122/18639	0.040983606557377	0.295968013414549	0.999910946962315	1
GO:0030594	neurotransmitter receptor activity	3/2581	97/18639	0.0309278350515464	0.223349057545825	0.999930080181273	1
GO:0008173	RNA methyltransferase activity	1/2581	67/18639	0.0149253731343284	0.107785366079328	0.999954844466849	1
GO:0140098	catalytic activity, acting on RNA	27/2581	387/18639	0.0697674418604651	0.503833920510348	0.999993988595568	1
GO:0140101	catalytic activity, acting on a tRNA	1/2581	139/18639	0.00719424460431655	0.0519540973188129	0.999999999074754	1
GO:0003735	structural constituent of ribosome	1/2581	175/18639	0.00571428571428571	0.0412663972989428	0.999999999995882	1
GO:0045182	translation regulator activity	12/2581	356/18639	0.0337078651685393	0.243425377325224	0.999999999996307	1
GO:0030371	translation repressor activity	9/2581	329/18639	0.027355623100304	0.197551901963024	0.9999999999994	1
GO:1903231	mRNA base-pairing translational repressor activity	1/2581	298/18639	0.00335570469798658	0.0242336225748825	1	1