ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 81/1704 175/18639 0.462857142857143 5.06290744466801 4.33903970088606e-38 4.95952237811276e-35 GO:0023026 MHC class II protein complex binding 15/1704 27/18639 0.555555555555556 6.0768779342723 1.47659651933405e-09 8.43874910799412e-07 GO:0031386 protein tag activity 11/1704 15/18639 0.733333333333333 8.02147887323944 3.49070237307638e-09 9.41235918430474e-07 GO:0141047 molecular tag activity 11/1704 15/18639 0.733333333333333 8.02147887323944 3.49070237307638e-09 9.41235918430474e-07 GO:0042277 peptide binding 53/1704 249/18639 0.21285140562249 2.32824961819107 4.11739246907469e-09 9.41235918430474e-07 GO:0023023 MHC protein complex binding 17/1704 37/18639 0.459459459459459 5.02574229158736 5.40537326290574e-09 1.02972360658354e-06 GO:0044389 ubiquitin-like protein ligase binding 62/1704 322/18639 0.192546583850932 2.10614775610183 1.24745833056997e-08 2.03692124548782e-06 GO:0031625 ubiquitin protein ligase binding 58/1704 302/18639 0.19205298013245 2.10074853092062 4.02136272022868e-08 5.74552198652672e-06 GO:0016209 antioxidant activity 24/1704 86/18639 0.27906976744186 3.0525712414019 4.61477867207871e-07 5.86076891353996e-05 GO:0019843 rRNA binding 20/1704 65/18639 0.307692307692308 3.36565547128927 7.52501606914945e-07 8.60109336703782e-05 GO:0001540 amyloid-beta binding 23/1704 83/18639 0.27710843373494 3.0311174274563 9.12686641823282e-07 9.48364392367283e-05 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 18/1704 59/18639 0.305084745762712 3.3371329672953 3.06036905180916e-06 0.000291500152184822 GO:0032395 MHC class II receptor activity 7/1704 10/18639 0.7 7.6568661971831 4.93840245856164e-06 0.000434199539241227 GO:0042605 peptide antigen binding 15/1704 45/18639 0.333333333333333 3.64612676056338 5.9903343956386e-06 0.000489068015301065 GO:0004601 peroxidase activity 17/1704 57/18639 0.298245614035088 3.26232394366197 8.05759445236781e-06 0.000613988697270427 GO:0043021 ribonucleoprotein complex binding 35/1704 177/18639 0.19774011299435 2.16295655287658 9.7300471982632e-06 0.000695090246725928 GO:0140313 molecular sequestering activity 16/1704 55/18639 0.290909090909091 3.1820742637644 2.09663237459954e-05 0.00140967694362781 GO:0019207 kinase regulator activity 48/1704 287/18639 0.167247386759582 1.82941551749522 2.9548815846734e-05 0.00187634980626761 GO:0140318 protein transporter activity 13/1704 41/18639 0.317073170731707 3.46826691858468 4.54650539111267e-05 0.00273508192739041 GO:0008429 phosphatidylethanolamine binding 8/1704 17/18639 0.470588235294118 5.14747307373654 5.48732621063144e-05 0.00313600692937587 GO:0019887 protein kinase regulator activity 43/1704 255/18639 0.168627450980392 1.84451118475559 6.17431024783446e-05 0.00336058886346419 GO:0017069 snRNA binding 15/1704 54/18639 0.277777777777778 3.03843896713615 6.8305496659298e-05 0.0035487810309808 GO:0140311 protein sequestering activity 11/1704 33/18639 0.333333333333333 3.64612676056338 0.00010477067880261 0.00520664721179927 GO:0009055 electron transfer activity 24/1704 116/18639 0.206896551724138 2.26311316172899 0.000111518152920261 0.00531105203282742 GO:0140375 immune receptor activity 29/1704 156/18639 0.185897435897436 2.03341684723727 0.000170920321810089 0.00781447711315727 GO:0003925 G protein activity 14/1704 54/18639 0.259259259259259 2.83587636932707 0.000263527063654947 0.0114931577602501 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 13/1704 48/18639 0.270833333333333 2.96247799295775 0.000271491915596459 0.0114931577602501 GO:0008320 protein transmembrane transporter activity 9/1704 27/18639 0.333333333333333 3.64612676056338 0.000446228326136674 0.0182156777419364 GO:0004602 glutathione peroxidase activity 8/1704 23/18639 0.347826086956522 3.80465401102266 0.000671717836775602 0.0264749478425694 GO:0031072 heat shock protein binding 24/1704 131/18639 0.183206106870229 2.00397806687453 0.000743165702332553 0.0283146132588703 GO:0038187 pattern recognition receptor activity 12/1704 48/18639 0.25 2.73459507042254 0.00101268634833746 0.0369395810875715 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 15/1704 68/18639 0.220588235294118 2.412878003314 0.00103417899807724 0.0369395810875715 GO:0031720 haptoglobin binding 5/1704 10/18639 0.5 5.46919014084507 0.00108033391295245 0.0374188382577168 GO:0008135 translation factor activity, RNA binding 17/1704 83/18639 0.204819277108434 2.24039114203292 0.00119782858087167 0.0402681784687154 GO:0180051 translation factor activity 17/1704 84/18639 0.202380952380952 2.21371981891348 0.00137624118662232 0.0449441050374089 GO:0003924 GTPase activity 47/1704 331/18639 0.141993957703928 1.55318390706778 0.00161164849647784 0.0510841469593973 GO:0022884 macromolecule transmembrane transporter activity 9/1704 32/18639 0.28125 3.07641945422535 0.00175738304189317 0.0510841469593973 GO:0003743 translation initiation factor activity 12/1704 51/18639 0.235294117647059 2.57373653686827 0.00178578027308082 0.0510841469593973 GO:0019864 IgG binding 5/1704 11/18639 0.454545454545455 4.97199103713188 0.00183191506837283 0.0510841469593973 GO:0042608 T cell receptor binding 5/1704 11/18639 0.454545454545455 4.97199103713188 0.00183191506837283 0.0510841469593973 GO:0003712 transcription coregulator activity 65/1704 495/18639 0.131313131313131 1.43635296628254 0.00186185887654631 0.0510841469593973 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/1704 58/18639 0.224137931034483 2.45170592520641 0.00187710776228757 0.0510841469593973 GO:0017070 U6 snRNA binding 6/1704 16/18639 0.375 4.1018926056338 0.00207056102872139 0.0550384012983384 GO:0001098 basal transcription machinery binding 13/1704 60/18639 0.216666666666667 2.3699823943662 0.00258930429581799 0.0657683291137771 GO:0001099 basal RNA polymerase II transcription machinery binding 13/1704 60/18639 0.216666666666667 2.3699823943662 0.00258930429581799 0.0657683291137771 GO:0036041 long-chain fatty acid binding 6/1704 17/18639 0.352941176470588 3.8606048053024 0.00295462751943979 0.0734160707547755 GO:0051082 unfolded protein binding 21/1704 121/18639 0.173553719008264 1.89839657781399 0.0030654053873345 0.0742136522827957 GO:0005525 GTP binding 51/1704 378/18639 0.134920634920635 1.47581321260899 0.00314160625081036 0.0742136522827957 GO:0008137 NADH dehydrogenase (ubiquinone) activity 10/1704 41/18639 0.24390243902439 2.66789762968052 0.0031815126525433 0.0742136522827957 GO:0045296 cadherin binding 46/1704 334/18639 0.137724550898204 1.50648351184954 0.00328404486431129 0.0750732655981561 GO:0030295 protein kinase activator activity 23/1704 139/18639 0.165467625899281 1.80994781639477 0.00374384489603042 0.0829830097497375 GO:0051540 metal cluster binding 15/1704 77/18639 0.194805194805195 2.13085330162795 0.00377525503673347 0.0829830097497375 GO:0060590 ATPase regulator activity 11/1704 49/18639 0.224489795918367 2.45555475711411 0.00404348988422138 0.0850569811205422 GO:0019209 kinase activator activity 24/1704 148/18639 0.162162162162162 1.77379139703083 0.00405429234188723 0.0850569811205422 GO:1990381 ubiquitin-specific protease binding 6/1704 18/18639 0.333333333333333 3.64612676056338 0.00409285560947491 0.0850569811205422 GO:0005035 death receptor activity 5/1704 13/18639 0.384615384615385 4.20706933911159 0.00436840335413504 0.087597983048708 GO:0019855 calcium channel inhibitor activity 5/1704 13/18639 0.384615384615385 4.20706933911159 0.00436840335413504 0.087597983048708 GO:0016504 peptidase activator activity 12/1704 57/18639 0.210526315789474 2.30281690140845 0.00477423455645904 0.0940853465178048 GO:0038024 cargo receptor activity 13/1704 65/18639 0.2 2.18767605633803 0.00536722800211863 0.103978671295281 GO:0003954 NADH dehydrogenase activity 10/1704 44/18639 0.227272727272727 2.48599551856594 0.00547670108777373 0.104331155722089 GO:0004197 cysteine-type endopeptidase activity 16/1704 88/18639 0.181818181818182 1.98879641485275 0.00573918910827253 0.105222313562645 GO:0016651 oxidoreductase activity, acting on NAD(P)H 16/1704 88/18639 0.181818181818182 1.98879641485275 0.00573918910827253 0.105222313562645 GO:0019211 phosphatase activator activity 7/1704 25/18639 0.28 3.06274647887324 0.00579965507825603 0.105222313562645 GO:0043022 ribosome binding 19/1704 112/18639 0.169642857142857 1.85561808350101 0.00606143671509364 0.105790900426562 GO:0019001 guanyl nucleotide binding 52/1704 400/18639 0.13 1.42198943661972 0.00610866091701933 0.105790900426562 GO:0032561 guanyl ribonucleotide binding 52/1704 400/18639 0.13 1.42198943661972 0.00610866091701933 0.105790900426562 GO:0005344 oxygen carrier activity 5/1704 14/18639 0.357142857142857 3.90656438631791 0.00628906487894335 0.107202197724609 GO:0070063 RNA polymerase binding 12/1704 59/18639 0.203389830508475 2.2247553115302 0.00637773354792074 0.107202197724609 GO:0030515 snoRNA binding 8/1704 32/18639 0.25 2.73459507042254 0.00686665569029411 0.113747644260959 GO:0019865 immunoglobulin binding 7/1704 26/18639 0.269230769230769 2.94494853737812 0.00732113721283705 0.118256282616785 GO:0019003 GDP binding 14/1704 75/18639 0.186666666666667 2.04183098591549 0.00744921465302584 0.118256282616785 GO:0044183 protein folding chaperone 14/1704 75/18639 0.186666666666667 2.04183098591549 0.00744921465302584 0.118256282616785 GO:0051536 iron-sulfur cluster binding 14/1704 76/18639 0.184210526315789 2.01496478873239 0.00838303149681459 0.131257602751494 GO:0055105 ubiquitin-protein transferase inhibitor activity 5/1704 15/18639 0.333333333333333 3.64612676056338 0.00873270320143825 0.134884861611404 GO:0001671 ATPase activator activity 7/1704 27/18639 0.259259259259259 2.83587636932707 0.00911873079394404 0.138969457299707 GO:0072542 protein phosphatase activator activity 6/1704 21/18639 0.285714285714286 3.12525150905433 0.00943233594835142 0.141857368275864 GO:0051087 protein-folding chaperone binding 21/1704 134/18639 0.156716417910448 1.71422377548875 0.0101090486465599 0.150060293545687 GO:0033218 amide binding 34/1704 247/18639 0.137651821862348 1.50568797399783 0.0104706178667484 0.153434823355043 GO:0051537 2 iron, 2 sulfur cluster binding 7/1704 28/18639 0.25 2.73459507042254 0.0112191933129012 0.162323265274002 GO:0004708 MAP kinase kinase activity 5/1704 16/18639 0.3125 3.41824383802817 0.0117609496435823 0.165938750130347 GO:0002020 protease binding 21/1704 136/18639 0.154411764705882 1.6890146023198 0.0118897632203955 0.165938750130347 GO:0061133 endopeptidase activator activity 6/1704 22/18639 0.272727272727273 2.98319462227913 0.0119856570867496 0.165938750130347 GO:0043175 RNA polymerase core enzyme binding 9/1704 42/18639 0.214285714285714 2.34393863179074 0.0121949737628601 0.165938750130347 GO:0048487 beta-tubulin binding 9/1704 42/18639 0.214285714285714 2.34393863179074 0.0121949737628601 0.165938750130347 GO:0032182 ubiquitin-like protein binding 19/1704 120/18639 0.158333333333333 1.73191021126761 0.0125693944905089 0.16902138709002 GO:0048306 calcium-dependent protein binding 14/1704 80/18639 0.175 1.91421654929577 0.0130769814208232 0.17380220655815 GO:0010854 adenylate cyclase regulator activity 4/1704 11/18639 0.363636363636364 3.97759282970551 0.0135931496214171 0.174572696823368 GO:0070990 snRNP binding 4/1704 11/18639 0.363636363636364 3.97759282970551 0.0135931496214171 0.174572696823368 GO:1990948 ubiquitin ligase inhibitor activity 4/1704 11/18639 0.363636363636364 3.97759282970551 0.0135931496214171 0.174572696823368 GO:0005048 signal sequence binding 10/1704 51/18639 0.196078431372549 2.14478044739022 0.0157458078924407 0.197774268363294 GO:0030544 Hsp70 protein binding 10/1704 51/18639 0.196078431372549 2.14478044739022 0.0157458078924407 0.197774268363294 GO:0043394 proteoglycan binding 8/1704 37/18639 0.216216216216216 2.36505519604111 0.0167713263388302 0.208365500057423 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 44/1704 349/18639 0.126074498567335 1.37905080915291 0.0180454578958407 0.212986612274642 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/1704 24/18639 0.25 2.73459507042254 0.0184756621597338 0.212986612274642 GO:0048027 mRNA 5'-UTR binding 6/1704 24/18639 0.25 2.73459507042254 0.0184756621597338 0.212986612274642 GO:0004875 complement receptor activity 4/1704 12/18639 0.333333333333333 3.64612676056338 0.0189370990124932 0.212986612274642 GO:0016273 arginine N-methyltransferase activity 4/1704 12/18639 0.333333333333333 3.64612676056338 0.0189370990124932 0.212986612274642 GO:0016274 protein-arginine N-methyltransferase activity 4/1704 12/18639 0.333333333333333 3.64612676056338 0.0189370990124932 0.212986612274642 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1704 12/18639 0.333333333333333 3.64612676056338 0.0189370990124932 0.212986612274642 GO:0008009 chemokine activity 9/1704 45/18639 0.2 2.18767605633803 0.018942633031952 0.212986612274642 GO:0051539 4 iron, 4 sulfur cluster binding 9/1704 45/18639 0.2 2.18767605633803 0.018942633031952 0.212986612274642 GO:0043130 ubiquitin binding 16/1704 100/18639 0.16 1.75014084507042 0.019006679310598 0.212986612274642 GO:0004860 protein kinase inhibitor activity 14/1704 84/18639 0.166666666666667 1.82306338028169 0.0195850312947503 0.217336803591259 GO:0032393 MHC class I receptor activity 5/1704 18/18639 0.277777777777778 3.03843896713615 0.0197907870360135 0.217508361366956 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 11/1704 61/18639 0.180327868852459 1.97249480489494 0.0212056252789997 0.230838378037111 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 19/1704 128/18639 0.1484375 1.62366582306338 0.0236697585254921 0.255231452779598 GO:0050145 nucleoside monophosphate kinase activity 5/1704 19/18639 0.263157894736842 2.87852112676056 0.0248856567990285 0.265834632909248 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 4/1704 13/18639 0.307692307692308 3.36565547128927 0.0254120748606525 0.26647707858464 GO:0032396 inhibitory MHC class I receptor activity 4/1704 13/18639 0.307692307692308 3.36565547128927 0.0254120748606525 0.26647707858464 GO:0004529 DNA exonuclease activity 6/1704 26/18639 0.230769230769231 2.52424160346696 0.0270258541298831 0.280823193367786 GO:0004857 enzyme inhibitor activity 50/1704 416/18639 0.120192307692308 1.31470916847237 0.0276218794351243 0.284430704453578 GO:0001530 lipopolysaccharide binding 8/1704 41/18639 0.195121951219512 2.13431810374442 0.0300376578075383 0.287160841597875 GO:0042287 MHC protein binding 8/1704 41/18639 0.195121951219512 2.13431810374442 0.0300376578075383 0.287160841597875 GO:0016408 C-acyltransferase activity 5/1704 20/18639 0.25 2.73459507042254 0.0307503024629725 0.287160841597875 GO:0016505 peptidase activator activity involved in apoptotic process 5/1704 20/18639 0.25 2.73459507042254 0.0307503024629725 0.287160841597875 GO:0042288 MHC class I protein binding 5/1704 20/18639 0.25 2.73459507042254 0.0307503024629725 0.287160841597875 GO:0043024 ribosomal small subunit binding 5/1704 20/18639 0.25 2.73459507042254 0.0307503024629725 0.287160841597875 GO:0016831 carboxy-lyase activity 7/1704 34/18639 0.205882352941176 2.25201946975973 0.0315739127519733 0.287160841597875 GO:0033192 calmodulin-dependent protein phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0140791 histone H2AXS140 phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:1990439 MAP kinase serine/threonine phosphatase activity 13/1704 81/18639 0.160493827160494 1.75554251434533 0.031655525845435 0.287160841597875 GO:0004364 glutathione transferase activity 6/1704 27/18639 0.222222222222222 2.43075117370892 0.0321421750830086 0.288063694322654 GO:0043539 protein serine/threonine kinase activator activity 12/1704 73/18639 0.164383561643836 1.79808990931893 0.0322591013764651 0.288063694322654 GO:0016530 metallochaperone activity 4/1704 14/18639 0.285714285714286 3.12525150905433 0.033061278853336 0.290684936379716 GO:0019763 immunoglobulin receptor activity 4/1704 14/18639 0.285714285714286 3.12525150905433 0.033061278853336 0.290684936379716 GO:0019210 kinase inhibitor activity 14/1704 90/18639 0.155555555555556 1.70152582159624 0.0335663542426998 0.29287284656035 GO:0042056 chemoattractant activity 8/1704 42/18639 0.19047619047619 2.08350100603622 0.0342359364062861 0.295046908735052 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 13/1704 82/18639 0.158536585365854 1.73413345929234 0.0345899263083963 0.295046908735052 GO:0033549 MAP kinase phosphatase activity 13/1704 82/18639 0.158536585365854 1.73413345929234 0.0345899263083963 0.295046908735052 GO:0009931 calcium-dependent protein serine/threonine kinase activity 5/1704 21/18639 0.238095238095238 2.60437625754527 0.0374121669987915 0.31122856233379 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 13/1704 83/18639 0.156626506024096 1.713240285084 0.0377141313084971 0.31122856233379 GO:0019789 SUMO transferase activity 6/1704 28/18639 0.214285714285714 2.34393863179074 0.0378484428384924 0.31122856233379 GO:0046966 nuclear thyroid hormone receptor binding 6/1704 28/18639 0.214285714285714 2.34393863179074 0.0378484428384924 0.31122856233379 GO:0051019 mitogen-activated protein kinase binding 6/1704 28/18639 0.214285714285714 2.34393863179074 0.0378484428384924 0.31122856233379 GO:0016830 carbon-carbon lyase activity 9/1704 51/18639 0.176470588235294 1.9303024026512 0.0398616005931157 0.322234278029559 GO:0022853 active monoatomic ion transmembrane transporter activity 17/1704 118/18639 0.144067796610169 1.57586834566722 0.0399585565758009 0.322234278029559 GO:0031593 polyubiquitin modification-dependent protein binding 10/1704 59/18639 0.169491525423729 1.8539627596085 0.0400326049695515 0.322234278029559 GO:0140789 histone phosphatase activity 19/1704 136/18639 0.139705882352941 1.52815606876553 0.0410224138501956 0.323654611120068 GO:0017018 myosin phosphatase activity 13/1704 84/18639 0.154761904761905 1.69284456740443 0.0410335439870704 0.323654611120068 GO:0000993 RNA polymerase II complex binding 7/1704 36/18639 0.194444444444444 2.12690727699531 0.0418197031349231 0.323654611120068 GO:0005484 SNAP receptor activity 7/1704 36/18639 0.194444444444444 2.12690727699531 0.0418197031349231 0.323654611120068 GO:0000774 adenyl-nucleotide exchange factor activity 4/1704 15/18639 0.266666666666667 2.9169014084507 0.0419080336358443 0.323654611120068 GO:0004129 cytochrome-c oxidase activity 4/1704 15/18639 0.266666666666667 2.9169014084507 0.0419080336358443 0.323654611120068 GO:0106222 lncRNA binding 6/1704 29/18639 0.206896551724138 2.26311316172899 0.0441614063812264 0.33876837244122 GO:0140517 protein-RNA adaptor activity 5/1704 22/18639 0.227272727272727 2.48599551856594 0.0448905522670392 0.342066008274838 GO:0002039 p53 binding 11/1704 69/18639 0.159420289855072 1.74379975505205 0.0476627876898351 0.36078520748001 GO:0141110 transporter inhibitor activity 8/1704 45/18639 0.177777777777778 1.94460093896714 0.0491556041963208 0.368865553849058 GO:0140296 general transcription initiation factor binding 9/1704 53/18639 0.169811320754717 1.85746080255116 0.0493757040585354 0.368865553849058 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/1704 16/18639 0.25 2.73459507042254 0.0519570616332651 0.375866591435582 GO:0005159 insulin-like growth factor receptor binding 4/1704 16/18639 0.25 2.73459507042254 0.0519570616332651 0.375866591435582 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/1704 16/18639 0.25 2.73459507042254 0.0519570616332651 0.375866591435582 GO:0034450 ubiquitin-ubiquitin ligase activity 4/1704 16/18639 0.25 2.73459507042254 0.0519570616332651 0.375866591435582 GO:0055102 lipase inhibitor activity 4/1704 16/18639 0.25 2.73459507042254 0.0519570616332651 0.375866591435582 GO:0001094 TFIID-class transcription factor complex binding 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:0005031 tumor necrosis factor receptor activity 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:0030957 Tat protein binding 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:0042975 peroxisome proliferator activated receptor binding 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:0051880 G-quadruplex DNA binding 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:0140940 histone H2A methyltransferase activity 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:1990259 histone H2AQ104 methyltransferase activity 3/1704 10/18639 0.3 3.28151408450704 0.0561551032345715 0.389001715134032 GO:0001221 transcription coregulator binding 16/1704 115/18639 0.139130434782609 1.52186160440906 0.05901966437088 0.406382387806722 GO:0140297 DNA-binding transcription factor binding 55/1704 488/18639 0.112704918032787 1.23280925305934 0.0609611296212321 0.415916769891802 GO:0005504 fatty acid binding 8/1704 47/18639 0.170212765957447 1.86185196284088 0.0611321236586376 0.415916769891802 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/1704 17/18639 0.235294117647059 2.57373653686827 0.0631960804346876 0.417532485184092 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 4/1704 17/18639 0.235294117647059 2.57373653686827 0.0631960804346876 0.417532485184092 GO:0045236 CXCR chemokine receptor binding 4/1704 17/18639 0.235294117647059 2.57373653686827 0.0631960804346876 0.417532485184092 GO:0051787 misfolded protein binding 4/1704 17/18639 0.235294117647059 2.57373653686827 0.0631960804346876 0.417532485184092 GO:1990226 histone methyltransferase binding 4/1704 17/18639 0.235294117647059 2.57373653686827 0.0631960804346876 0.417532485184092 GO:0061659 ubiquitin-like protein ligase activity 43/1704 372/18639 0.115591397849462 1.26438266696956 0.0649464662309397 0.426631097137724 GO:0031369 translation initiation factor binding 6/1704 32/18639 0.1875 2.0509463028169 0.0668439596007897 0.430105683396958 GO:0071813 lipoprotein particle binding 6/1704 32/18639 0.1875 2.0509463028169 0.0668439596007897 0.430105683396958 GO:0071814 protein-lipid complex binding 6/1704 32/18639 0.1875 2.0509463028169 0.0668439596007897 0.430105683396958 GO:0019208 phosphatase regulator activity 16/1704 117/18639 0.136752136752137 1.49584687612857 0.0669805876156242 0.430105683396958 GO:0140693 molecular condensate scaffold activity 8/1704 48/18639 0.166666666666667 1.82306338028169 0.0677483647450539 0.43063057138921 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 7/1704 40/18639 0.175 1.91421654929577 0.0681925926696824 0.43063057138921 GO:0140662 ATP-dependent protein folding chaperone 7/1704 40/18639 0.175 1.91421654929577 0.0681925926696824 0.43063057138921 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/1704 11/18639 0.272727272727273 2.98319462227913 0.0721158358395045 0.437228016729348 GO:0001851 complement component C3b binding 3/1704 11/18639 0.272727272727273 2.98319462227913 0.0721158358395045 0.437228016729348 GO:0008199 ferric iron binding 3/1704 11/18639 0.272727272727273 2.98319462227913 0.0721158358395045 0.437228016729348 GO:0032794 GTPase activating protein binding 3/1704 11/18639 0.272727272727273 2.98319462227913 0.0721158358395045 0.437228016729348 GO:0043522 leucine zipper domain binding 3/1704 11/18639 0.272727272727273 2.98319462227913 0.0721158358395045 0.437228016729348 GO:0050786 RAGE receptor binding 3/1704 11/18639 0.272727272727273 2.98319462227913 0.0721158358395045 0.437228016729348 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/1704 25/18639 0.2 2.18767605633803 0.0722975460733568 0.437228016729348 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/1704 25/18639 0.2 2.18767605633803 0.0722975460733568 0.437228016729348 GO:0034185 apolipoprotein binding 4/1704 18/18639 0.222222222222222 2.43075117370892 0.0755975928343088 0.448056120400427 GO:0050811 GABA receptor binding 4/1704 18/18639 0.222222222222222 2.43075117370892 0.0755975928343088 0.448056120400427 GO:0070628 proteasome binding 4/1704 18/18639 0.222222222222222 2.43075117370892 0.0755975928343088 0.448056120400427 GO:0030296 protein tyrosine kinase activator activity 6/1704 33/18639 0.181818181818182 1.98879641485275 0.0756657385391814 0.448056120400427 GO:0061650 ubiquitin-like protein conjugating enzyme activity 7/1704 41/18639 0.170731707317073 1.86752834077637 0.076048020435418 0.448056120400427 GO:0015399 primary active transmembrane transporter activity 21/1704 166/18639 0.126506024096386 1.38377099949092 0.0794507364749886 0.464383711180592 GO:0051117 ATPase binding 12/1704 84/18639 0.142857142857143 1.56262575452716 0.0796318524859108 0.464383711180592 GO:0050840 extracellular matrix binding 10/1704 67/18639 0.149253731343284 1.63259407189405 0.0823391814174131 0.477734438376158 GO:0097602 cullin family protein binding 5/1704 26/18639 0.192307692307692 2.1035346695558 0.0830765203456124 0.479578094722399 GO:0019787 ubiquitin-like protein transferase activity 53/1704 479/18639 0.110647181628392 1.2103009497486 0.0835855508785742 0.480091882684474 GO:0035198 miRNA binding 7/1704 42/18639 0.166666666666667 1.82306338028169 0.0844104372412443 0.482405648833711 GO:0019825 oxygen binding 6/1704 34/18639 0.176470588235294 1.9303024026512 0.0851139869221546 0.484006403243894 GO:0070003 threonine-type peptidase activity 4/1704 19/18639 0.210526315789474 2.30281690140845 0.0891207757770503 0.493699514882908 GO:0097001 ceramide binding 4/1704 19/18639 0.210526315789474 2.30281690140845 0.0891207757770503 0.493699514882908 GO:0004859 phospholipase inhibitor activity 3/1704 12/18639 0.25 2.73459507042254 0.0898420814485081 0.493699514882908 GO:0010853 cyclase activator activity 3/1704 12/18639 0.25 2.73459507042254 0.0898420814485081 0.493699514882908 GO:0035497 cAMP response element binding 3/1704 12/18639 0.25 2.73459507042254 0.0898420814485081 0.493699514882908 GO:0036009 protein-glutamine N-methyltransferase activity 3/1704 12/18639 0.25 2.73459507042254 0.0898420814485081 0.493699514882908 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1704 12/18639 0.25 2.73459507042254 0.0898420814485081 0.493699514882908 GO:0008200 ion channel inhibitor activity 7/1704 43/18639 0.162790697674419 1.78066655748444 0.0932763287661254 0.507689732284197 GO:0048156 tau protein binding 7/1704 43/18639 0.162790697674419 1.78066655748444 0.0932763287661254 0.507689732284197 GO:0035255 ionotropic glutamate receptor binding 5/1704 27/18639 0.185185185185185 2.02562597809077 0.0946525079052951 0.508369381085665 GO:0003713 transcription coactivator activity 30/1704 256/18639 0.1171875 1.28184143926056 0.0946622093935545 0.508369381085665 GO:0005154 epidermal growth factor receptor binding 6/1704 35/18639 0.171428571428571 1.8751509054326 0.0951802690746564 0.508369381085665 GO:0061631 ubiquitin conjugating enzyme activity 6/1704 35/18639 0.171428571428571 1.8751509054326 0.0951802690746564 0.508369381085665 GO:0051020 GTPase binding 36/1704 315/18639 0.114285714285714 1.25010060362173 0.0959295810619469 0.509988423971188 GO:0030159 signaling receptor complex adaptor activity 8/1704 52/18639 0.153846153846154 1.68282773564464 0.0984440783159492 0.520933247755231 GO:0016755 aminoacyltransferase activity 54/1704 496/18639 0.108870967741935 1.19087204679691 0.100964069158568 0.531465222943249 GO:0001223 transcription coactivator binding 7/1704 44/18639 0.159090909090909 1.74019686299616 0.102639664877052 0.531465222943249 GO:0016248 channel inhibitor activity 7/1704 44/18639 0.159090909090909 1.74019686299616 0.102639664877052 0.531465222943249 GO:0097110 scaffold protein binding 10/1704 70/18639 0.142857142857143 1.56262575452716 0.103374109953647 0.531465222943249 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 4/1704 20/18639 0.2 2.18767605633803 0.10371339410557 0.531465222943249 GO:0010851 cyclase regulator activity 4/1704 20/18639 0.2 2.18767605633803 0.10371339410557 0.531465222943249 GO:0016004 phospholipase activator activity 4/1704 20/18639 0.2 2.18767605633803 0.10371339410557 0.531465222943249 GO:0033293 monocarboxylic acid binding 11/1704 79/18639 0.139240506329114 1.52306560884293 0.104154164426324 0.531465222943249 GO:0055106 ubiquitin-protein transferase regulator activity 6/1704 36/18639 0.166666666666667 1.82306338028169 0.105852382262603 0.537730101894023 GO:0005246 calcium channel regulator activity 8/1704 53/18639 0.150943396226415 1.65107626893436 0.107167344850601 0.537855811873365 GO:0019888 protein phosphatase regulator activity 14/1704 107/18639 0.130841121495327 1.43118994339871 0.108963762228952 0.537855811873365 GO:0017154 semaphorin receptor activity 3/1704 13/18639 0.230769230769231 2.52424160346696 0.109171083424865 0.537855811873365 GO:0031994 insulin-like growth factor I binding 3/1704 13/18639 0.230769230769231 2.52424160346696 0.109171083424865 0.537855811873365 GO:0035325 Toll-like receptor binding 3/1704 13/18639 0.230769230769231 2.52424160346696 0.109171083424865 0.537855811873365 GO:0043560 insulin receptor substrate binding 3/1704 13/18639 0.230769230769231 2.52424160346696 0.109171083424865 0.537855811873365 GO:0071714 icosanoid transmembrane transporter activity 3/1704 13/18639 0.230769230769231 2.52424160346696 0.109171083424865 0.537855811873365 GO:1990782 protein tyrosine kinase binding 15/1704 117/18639 0.128205128205128 1.40235644637053 0.113463788852658 0.556605625144154 GO:0140463 chromatin-protein adaptor activity 8/1704 54/18639 0.148148148148148 1.62050078247261 0.116300921904653 0.568085272380418 GO:0042379 chemokine receptor binding 10/1704 72/18639 0.138888888888889 1.51921948356808 0.118969615334873 0.57864795884153 GO:0043236 laminin binding 5/1704 29/18639 0.172413793103448 1.88592763477416 0.120092845061009 0.581636109765821 GO:0016922 nuclear receptor binding 17/1704 137/18639 0.124087591240876 1.35731726123162 0.120735093967754 0.582279377236892 GO:0015078 proton transmembrane transporter activity 22/1704 185/18639 0.118918918918919 1.30078035782261 0.121772852214604 0.584816681013834 GO:0008174 mRNA methyltransferase activity 3/1704 14/18639 0.214285714285714 2.34393863179074 0.129928302853464 0.608639549842251 GO:0008191 metalloendopeptidase inhibitor activity 3/1704 14/18639 0.214285714285714 2.34393863179074 0.129928302853464 0.608639549842251 GO:0008474 palmitoyl-(protein) hydrolase activity 3/1704 14/18639 0.214285714285714 2.34393863179074 0.129928302853464 0.608639549842251 GO:0044548 S100 protein binding 3/1704 14/18639 0.214285714285714 2.34393863179074 0.129928302853464 0.608639549842251 GO:0061665 SUMO ligase activity 3/1704 14/18639 0.214285714285714 2.34393863179074 0.129928302853464 0.608639549842251 GO:0098599 palmitoyl hydrolase activity 3/1704 14/18639 0.214285714285714 2.34393863179074 0.129928302853464 0.608639549842251 GO:0008234 cysteine-type peptidase activity 22/1704 187/18639 0.117647058823529 1.28686826843413 0.132006459958712 0.613751046035056 GO:0052689 carboxylic ester hydrolase activity 12/1704 92/18639 0.130434782608696 1.4267452541335 0.132821257085903 0.613751046035056 GO:0001784 phosphotyrosine residue binding 7/1704 47/18639 0.148936170212766 1.62912046748577 0.133618366604221 0.613751046035056 GO:0043495 protein-membrane adaptor activity 7/1704 47/18639 0.148936170212766 1.62912046748577 0.133618366604221 0.613751046035056 GO:0031210 phosphatidylcholine binding 5/1704 30/18639 0.166666666666667 1.82306338028169 0.13389270061731 0.613751046035056 GO:0008649 rRNA methyltransferase activity 4/1704 22/18639 0.181818181818182 1.98879641485275 0.135852156296474 0.613751046035056 GO:0031683 G-protein beta/gamma-subunit complex binding 4/1704 22/18639 0.181818181818182 1.98879641485275 0.135852156296474 0.613751046035056 GO:0034062 5'-3' RNA polymerase activity 4/1704 22/18639 0.181818181818182 1.98879641485275 0.135852156296474 0.613751046035056 GO:0097747 RNA polymerase activity 4/1704 22/18639 0.181818181818182 1.98879641485275 0.135852156296474 0.613751046035056 GO:0004722 protein serine/threonine phosphatase activity 13/1704 103/18639 0.12621359223301 1.38057226856283 0.145583355693594 0.655125100621172 GO:0140104 molecular carrier activity 28/1704 249/18639 0.112449799196787 1.23001866621415 0.147534729734047 0.660303582092942 GO:0047499 calcium-independent phospholipase A2 activity 5/1704 31/18639 0.161290322580645 1.76425488414357 0.148361850622708 0.660303582092942 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0005041 low-density lipoprotein particle receptor activity 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0005523 tropomyosin binding 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0045504 dynein heavy chain binding 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0050700 CARD domain binding 3/1704 15/18639 0.2 2.18767605633803 0.151933370157869 0.660303582092942 GO:0140102 catalytic activity, acting on a rRNA 4/1704 23/18639 0.173913043478261 1.90232700551133 0.153253314325394 0.663517190431535 GO:0008173 RNA methyltransferase activity 9/1704 67/18639 0.134328358208955 1.46933466470465 0.155691952392342 0.671531704092253 GO:0061980 regulatory RNA binding 8/1704 58/18639 0.137931034482759 1.50874210781933 0.156762845066075 0.673608766580914 GO:0008201 heparin binding 20/1704 172/18639 0.116279069767442 1.27190468391746 0.15741535200812 0.673879203540379 GO:0019955 cytokine binding 17/1704 144/18639 0.118055555555556 1.29133656103286 0.165400780796426 0.704751454568875 GO:1990841 promoter-specific chromatin binding 9/1704 68/18639 0.132352941176471 1.4477268019884 0.165860141101511 0.704751454568875 GO:0042169 SH2 domain binding 6/1704 41/18639 0.146341463414634 1.60073857780831 0.167640616286277 0.70774701663462 GO:0045309 protein phosphorylated amino acid binding 8/1704 59/18639 0.135593220338983 1.4831702076868 0.1678035358775 0.70774701663462 GO:0004622 lysophospholipase activity 4/1704 24/18639 0.166666666666667 1.82306338028169 0.171437225348159 0.715156016689583 GO:0035035 histone acetyltransferase binding 4/1704 24/18639 0.166666666666667 1.82306338028169 0.171437225348159 0.715156016689583 GO:0060229 lipase activator activity 4/1704 24/18639 0.166666666666667 1.82306338028169 0.171437225348159 0.715156016689583 GO:0005521 lamin binding 3/1704 16/18639 0.1875 2.0509463028169 0.175004825971239 0.716955254785397 GO:0008142 oxysterol binding 3/1704 16/18639 0.1875 2.0509463028169 0.175004825971239 0.716955254785397 GO:0008296 3'-5'-DNA exonuclease activity 3/1704 16/18639 0.1875 2.0509463028169 0.175004825971239 0.716955254785397 GO:0030275 LRR domain binding 3/1704 16/18639 0.1875 2.0509463028169 0.175004825971239 0.716955254785397 GO:0070411 I-SMAD binding 3/1704 16/18639 0.1875 2.0509463028169 0.175004825971239 0.716955254785397 GO:0004721 phosphoprotein phosphatase activity 20/1704 175/18639 0.114285714285714 1.25010060362173 0.176396655524715 0.720076347374103 GO:0019956 chemokine binding 5/1704 33/18639 0.151515151515152 1.65733034571063 0.17913490240828 0.72350245036277 GO:0071889 14-3-3 protein binding 5/1704 33/18639 0.151515151515152 1.65733034571063 0.17913490240828 0.72350245036277 GO:0140416 transcription regulator inhibitor activity 5/1704 33/18639 0.151515151515152 1.65733034571063 0.17913490240828 0.72350245036277 GO:0004842 ubiquitin-protein transferase activity 47/1704 449/18639 0.10467706013363 1.14499749051099 0.181929553113524 0.732202391580135 GO:0042826 histone deacetylase binding 15/1704 127/18639 0.118110236220472 1.29193467893978 0.183360577734313 0.735372422281824 GO:0061134 peptidase regulator activity 25/1704 226/18639 0.110619469026549 1.20999781877103 0.184436724030927 0.737046762433776 GO:0001848 complement binding 4/1704 25/18639 0.16 1.75014084507042 0.190320973781455 0.737046762433776 GO:0015645 fatty acid ligase activity 4/1704 25/18639 0.16 1.75014084507042 0.190320973781455 0.737046762433776 GO:0019706 protein-cysteine S-palmitoyltransferase activity 4/1704 25/18639 0.16 1.75014084507042 0.190320973781455 0.737046762433776 GO:0019707 protein-cysteine S-acyltransferase activity 4/1704 25/18639 0.16 1.75014084507042 0.190320973781455 0.737046762433776 GO:0042974 nuclear retinoic acid receptor binding 4/1704 25/18639 0.16 1.75014084507042 0.190320973781455 0.737046762433776 GO:0120515 fatty acid-CoA ligase activity 4/1704 25/18639 0.16 1.75014084507042 0.190320973781455 0.737046762433776 GO:0046982 protein heterodimerization activity 39/1704 369/18639 0.105691056910569 1.15608897286156 0.190600124486512 0.737046762433776 GO:0005080 protein kinase C binding 7/1704 52/18639 0.134615384615385 1.47247426868906 0.193988777832487 0.737046762433776 GO:0008175 tRNA methyltransferase activity 5/1704 34/18639 0.147058823529412 1.60858533554267 0.195345405078302 0.737046762433776 GO:0030332 cyclin binding 5/1704 34/18639 0.147058823529412 1.60858533554267 0.195345405078302 0.737046762433776 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/1704 43/18639 0.13953488372093 1.52628562070095 0.195820850744213 0.737046762433776 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0005092 GDP-dissociation inhibitor activity 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0019198 transmembrane receptor protein phosphatase activity 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0030169 low-density lipoprotein particle binding 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0031489 myosin V binding 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0032977 membrane insertase activity 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0048038 quinone binding 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0070492 oligosaccharide binding 3/1704 17/18639 0.176470588235294 1.9303024026512 0.198963842871928 0.737046762433776 GO:0035591 signaling adaptor activity 15/1704 129/18639 0.116279069767442 1.27190468391746 0.199446686458822 0.737046762433776 GO:0003779 actin binding 46/1704 443/18639 0.103837471783296 1.13581375385496 0.200132611303171 0.737046762433776 GO:0001618 virus receptor activity 10/1704 81/18639 0.123456790123457 1.35041731872718 0.203586040559372 0.737046762433776 GO:0030971 receptor tyrosine kinase binding 10/1704 81/18639 0.123456790123457 1.35041731872718 0.203586040559372 0.737046762433776 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/1704 53/18639 0.132075471698113 1.44469173531757 0.207200735025383 0.737046762433776 GO:0005518 collagen binding 9/1704 72/18639 0.125 1.36729753521127 0.209450630486063 0.737046762433776 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1704 26/18639 0.153846153846154 1.68282773564464 0.209819965315244 0.737046762433776 GO:0008198 ferrous iron binding 4/1704 26/18639 0.153846153846154 1.68282773564464 0.209819965315244 0.737046762433776 GO:0043548 phosphatidylinositol 3-kinase binding 4/1704 26/18639 0.153846153846154 1.68282773564464 0.209819965315244 0.737046762433776 GO:0050750 low-density lipoprotein particle receptor binding 4/1704 26/18639 0.153846153846154 1.68282773564464 0.209819965315244 0.737046762433776 GO:0070412 R-SMAD binding 4/1704 26/18639 0.153846153846154 1.68282773564464 0.209819965315244 0.737046762433776 GO:0004623 phospholipase A2 activity 5/1704 35/18639 0.142857142857143 1.56262575452716 0.212039594412243 0.737046762433776 GO:0140566 histone reader activity 5/1704 35/18639 0.142857142857143 1.56262575452716 0.212039594412243 0.737046762433776 GO:0061630 ubiquitin protein ligase activity 37/1704 353/18639 0.104815864022663 1.14651578023381 0.212477973431986 0.737046762433776 GO:0140272 exogenous protein binding 10/1704 82/18639 0.121951219512195 1.33394881484026 0.214286261391635 0.737046762433776 GO:0005178 integrin binding 18/1704 161/18639 0.111801242236025 1.222924503543 0.217803460712007 0.737046762433776 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1704 54/18639 0.12962962962963 1.41793818466354 0.220739005064641 0.737046762433776 GO:0050661 NADP binding 7/1704 54/18639 0.12962962962963 1.41793818466354 0.220739005064641 0.737046762433776 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0003746 translation elongation factor activity 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0008409 5'-3' exonuclease activity 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0008525 phosphatidylcholine transporter activity 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0030228 lipoprotein particle receptor activity 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0035615 clathrin adaptor activity 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0070064 proline-rich region binding 3/1704 18/18639 0.166666666666667 1.82306338028169 0.223637092879452 0.737046762433776 GO:0004536 DNA nuclease activity 8/1704 64/18639 0.125 1.36729753521127 0.227820390027385 0.737046762433776 GO:0051219 phosphoprotein binding 11/1704 93/18639 0.118279569892473 1.29378691503862 0.22824696707382 0.737046762433776 GO:0016409 palmitoyltransferase activity 5/1704 36/18639 0.138888888888889 1.51921948356808 0.229166564113797 0.737046762433776 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/1704 36/18639 0.138888888888889 1.51921948356808 0.229166564113797 0.737046762433776 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/1704 36/18639 0.138888888888889 1.51921948356808 0.229166564113797 0.737046762433776 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/1704 36/18639 0.138888888888889 1.51921948356808 0.229166564113797 0.737046762433776 GO:0016405 CoA-ligase activity 4/1704 27/18639 0.148148148148148 1.62050078247261 0.229849088343062 0.737046762433776 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/1704 27/18639 0.148148148148148 1.62050078247261 0.229849088343062 0.737046762433776 GO:0000182 rDNA binding 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0004090 carbonyl reductase (NADPH) activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0005345 purine nucleobase transmembrane transporter activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0008140 cAMP response element binding protein binding 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0008190 eukaryotic initiation factor 4E binding 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0016427 tRNA (cytidine) methyltransferase activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0016783 sulfurtransferase activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0031956 medium-chain fatty acid-CoA ligase activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0050308 sugar-phosphatase activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0070513 death domain binding 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0099122 RNA polymerase II C-terminal domain binding 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:1905394 retromer complex binding 2/1704 10/18639 0.2 2.18767605633803 0.230851041952136 0.737046762433776 GO:0005126 cytokine receptor binding 29/1704 275/18639 0.105454545454545 1.1535019206146 0.235113343843583 0.748564211735975 GO:0003714 transcription corepressor activity 22/1704 204/18639 0.107843137254902 1.17962924606462 0.237885599415478 0.755286778144142 GO:0003823 antigen binding 19/1704 174/18639 0.109195402298851 1.19442083535697 0.240684122087539 0.761061731122071 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1704 46/18639 0.130434782608696 1.4267452541335 0.24103617381119 0.761061731122071 GO:0005520 insulin-like growth factor binding 3/1704 19/18639 0.157894736842105 1.72711267605634 0.248858902336152 0.773297371170703 GO:0030506 ankyrin binding 3/1704 19/18639 0.157894736842105 1.72711267605634 0.248858902336152 0.773297371170703 GO:0042834 peptidoglycan binding 3/1704 19/18639 0.157894736842105 1.72711267605634 0.248858902336152 0.773297371170703 GO:0043395 heparan sulfate proteoglycan binding 3/1704 19/18639 0.157894736842105 1.72711267605634 0.248858902336152 0.773297371170703 GO:0140036 ubiquitin-modified protein reader activity 3/1704 19/18639 0.157894736842105 1.72711267605634 0.248858902336152 0.773297371170703 GO:0046625 sphingolipid binding 4/1704 28/18639 0.142857142857143 1.56262575452716 0.250323733449834 0.773297371170703 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/1704 28/18639 0.142857142857143 1.56262575452716 0.250323733449834 0.773297371170703 GO:0097718 disordered domain specific binding 4/1704 28/18639 0.142857142857143 1.56262575452716 0.250323733449834 0.773297371170703 GO:0000149 SNARE binding 12/1704 106/18639 0.113207547169811 1.23830720170077 0.261061826285419 0.799257262518681 GO:0042162 telomeric DNA binding 5/1704 38/18639 0.131578947368421 1.43926056338028 0.26451208282889 0.799257262518681 GO:0005536 D-glucose binding 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0008432 JUN kinase binding 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0015205 nucleobase transmembrane transporter activity 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0019107 myristoyltransferase activity 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0019203 carbohydrate phosphatase activity 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0140537 transcription regulator activator activity 2/1704 11/18639 0.181818181818182 1.98879641485275 0.266125532199388 0.799257262518681 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/1704 29/18639 0.137931034482759 1.50874210781933 0.271160675592046 0.799257262518681 GO:0016417 S-acyltransferase activity 4/1704 29/18639 0.137931034482759 1.50874210781933 0.271160675592046 0.799257262518681 GO:0051861 glycolipid binding 4/1704 29/18639 0.137931034482759 1.50874210781933 0.271160675592046 0.799257262518681 GO:0097472 cyclin-dependent protein kinase activity 4/1704 29/18639 0.137931034482759 1.50874210781933 0.271160675592046 0.799257262518681 GO:0000339 RNA cap binding 3/1704 20/18639 0.15 1.64075704225352 0.274472815553314 0.799257262518681 GO:0001614 purinergic nucleotide receptor activity 3/1704 20/18639 0.15 1.64075704225352 0.274472815553314 0.799257262518681 GO:0016502 nucleotide receptor activity 3/1704 20/18639 0.15 1.64075704225352 0.274472815553314 0.799257262518681 GO:0030742 GTP-dependent protein binding 3/1704 20/18639 0.15 1.64075704225352 0.274472815553314 0.799257262518681 GO:0140939 histone H4 methyltransferase activity 3/1704 20/18639 0.15 1.64075704225352 0.274472815553314 0.799257262518681 GO:0030145 manganese ion binding 8/1704 68/18639 0.117647058823529 1.28686826843413 0.28052885160273 0.799257262518681 GO:0140223 general transcription initiation factor activity 8/1704 68/18639 0.117647058823529 1.28686826843413 0.28052885160273 0.799257262518681 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/1704 39/18639 0.128205128205128 1.40235644637053 0.282627067449867 0.799257262518681 GO:0016776 phosphotransferase activity, phosphate group as acceptor 5/1704 39/18639 0.128205128205128 1.40235644637053 0.282627067449867 0.799257262518681 GO:0004725 protein tyrosine phosphatase activity 11/1704 98/18639 0.112244897959184 1.22777737855706 0.282707627511336 0.799257262518681 GO:0031267 small GTPase binding 29/1704 283/18639 0.102473498233216 1.12089409247001 0.285930951848176 0.799257262518681 GO:0019902 phosphatase binding 20/1704 190/18639 0.105263157894737 1.15140845070423 0.286806498434941 0.799257262518681 GO:0070851 growth factor receptor binding 15/1704 139/18639 0.107913669064748 1.18040074982268 0.288465271342563 0.799257262518681 GO:0001222 transcription corepressor binding 6/1704 49/18639 0.122448979591837 1.33939350388043 0.288953786950563 0.799257262518681 GO:0035254 glutamate receptor binding 6/1704 49/18639 0.122448979591837 1.33939350388043 0.288953786950563 0.799257262518681 GO:0001968 fibronectin binding 4/1704 30/18639 0.133333333333333 1.45845070422535 0.292278825588159 0.799257262518681 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1704 30/18639 0.133333333333333 1.45845070422535 0.292278825588159 0.799257262518681 GO:0070566 adenylyltransferase activity 4/1704 30/18639 0.133333333333333 1.45845070422535 0.292278825588159 0.799257262518681 GO:0004620 phospholipase activity 12/1704 109/18639 0.110091743119266 1.20422535211268 0.293005025913888 0.799257262518681 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/1704 89/18639 0.112359550561798 1.22903149232473 0.294704622122202 0.799257262518681 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/1704 89/18639 0.112359550561798 1.22903149232473 0.294704622122202 0.799257262518681 GO:0016298 lipase activity 14/1704 130/18639 0.107692307692308 1.17797941495125 0.300099607554304 0.799257262518681 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1704 21/18639 0.142857142857143 1.56262575452716 0.300332671006104 0.799257262518681 GO:0001846 opsonin binding 3/1704 21/18639 0.142857142857143 1.56262575452716 0.300332671006104 0.799257262518681 GO:0019200 carbohydrate kinase activity 3/1704 21/18639 0.142857142857143 1.56262575452716 0.300332671006104 0.799257262518681 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1704 21/18639 0.142857142857143 1.56262575452716 0.300332671006104 0.799257262518681 GO:0140312 cargo adaptor activity 3/1704 21/18639 0.142857142857143 1.56262575452716 0.300332671006104 0.799257262518681 GO:0050997 quaternary ammonium group binding 5/1704 40/18639 0.125 1.36729753521127 0.300968531118203 0.799257262518681 GO:0061791 GTPase motor activity 5/1704 40/18639 0.125 1.36729753521127 0.300968531118203 0.799257262518681 GO:1990606 membrane scission GTPase motor activity 5/1704 40/18639 0.125 1.36729753521127 0.300968531118203 0.799257262518681 GO:0000340 RNA 7-methylguanosine cap binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0004032 aldose reductase (NADPH) activity 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0004300 enoyl-CoA hydratase activity 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0005025 transforming growth factor beta receptor activity, type I 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0005026 transforming growth factor beta receptor activity, type II 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0008179 adenylate cyclase binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0015132 prostaglandin transmembrane transporter activity 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0016361 activin receptor activity, type I 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0016362 activin receptor activity, type II 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0017002 activin receptor activity 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0035259 nuclear glucocorticoid receptor binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0042301 phosphate ion binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0070410 co-SMAD binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0097371 MDM2/MDM4 family protein binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:0097677 STAT family protein binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:1990459 transferrin receptor binding 2/1704 12/18639 0.166666666666667 1.82306338028169 0.301382222349564 0.799257262518681 GO:1901681 sulfur compound binding 28/1704 275/18639 0.101818181818182 1.11372599231754 0.302183876427939 0.799528173048922 GO:0140793 histone H2AXY142 phosphatase activity 10/1704 90/18639 0.111111111111111 1.21537558685446 0.306824330482885 0.809569953559401 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 7/1704 60/18639 0.116666666666667 1.27614436619718 0.307395765393508 0.809569953559401 GO:0016878 acid-thiol ligase activity 4/1704 31/18639 0.129032258064516 1.41140390731486 0.313599858916374 0.822120731058292 GO:0070325 lipoprotein particle receptor binding 4/1704 31/18639 0.129032258064516 1.41140390731486 0.313599858916374 0.822120731058292 GO:0019905 syntaxin binding 7/1704 61/18639 0.114754098360656 1.25522396675133 0.322497385812665 0.841363284556719 GO:0061135 endopeptidase regulator activity 19/1704 184/18639 0.103260869565217 1.12950665952235 0.323040418294447 0.841363284556719 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 13/1704 122/18639 0.10655737704918 1.16556511198338 0.323148278145581 0.841363284556719 GO:0033691 sialic acid binding 3/1704 22/18639 0.136363636363636 1.49159731113956 0.326303278591834 0.842013561172104 GO:0140035 ubiquitin-like protein reader activity 3/1704 22/18639 0.136363636363636 1.49159731113956 0.326303278591834 0.842013561172104 GO:0042578 phosphoric ester hydrolase activity 36/1704 363/18639 0.0991735537190083 1.08479804446514 0.328097879833037 0.842013561172104 GO:0001216 DNA-binding transcription activator activity 48/1704 491/18639 0.0977596741344195 1.06933249189639 0.333097254090278 0.842013561172104 GO:0047498 calcium-dependent phospholipase A2 activity 4/1704 32/18639 0.125 1.36729753521127 0.335048730709069 0.842013561172104 GO:0070717 poly-purine tract binding 4/1704 32/18639 0.125 1.36729753521127 0.335048730709069 0.842013561172104 GO:0004465 lipoprotein lipase activity 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0005172 vascular endothelial growth factor receptor binding 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0008035 high-density lipoprotein particle binding 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0008253 5'-nucleotidase activity 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0031432 titin binding 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0070123 transforming growth factor beta receptor activity, type III 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0097157 pre-mRNA intronic binding 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0140666 annealing activity 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0140852 histone ubiquitin ligase activity 2/1704 13/18639 0.153846153846154 1.68282773564464 0.336329702154054 0.842013561172104 GO:0030246 carbohydrate binding 28/1704 280/18639 0.1 1.09383802816901 0.337066540447286 0.842013561172104 GO:0019903 protein phosphatase binding 15/1704 144/18639 0.104166666666667 1.13941461267606 0.337072859070374 0.842013561172104 GO:0016859 cis-trans isomerase activity 5/1704 42/18639 0.119047619047619 1.30218812877264 0.338131430076987 0.842013561172104 GO:0051879 Hsp90 protein binding 5/1704 42/18639 0.119047619047619 1.30218812877264 0.338131430076987 0.842013561172104 GO:0005516 calmodulin binding 21/1704 207/18639 0.101449275362319 1.10969075321494 0.341069046230868 0.847482434438874 GO:0140098 catalytic activity, acting on RNA 38/1704 387/18639 0.0981912144702842 1.07405284419696 0.345434253767251 0.856467141119235 GO:0005158 insulin receptor binding 3/1704 23/18639 0.130434782608696 1.4267452541335 0.352260773231801 0.867763279279202 GO:0043274 phospholipase binding 3/1704 23/18639 0.130434782608696 1.4267452541335 0.352260773231801 0.867763279279202 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 47/1704 484/18639 0.0971074380165289 1.06219808520545 0.352806973155336 0.867763279279202 GO:0005507 copper ion binding 7/1704 63/18639 0.111111111111111 1.21537558685446 0.353027055874741 0.867763279279202 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1704 33/18639 0.121212121212121 1.3258642765685 0.356554086336764 0.874552190306698 GO:0016791 phosphatase activity 27/1704 273/18639 0.0989010989010989 1.08181783005727 0.362770624039105 0.887894696523977 GO:0048029 monosaccharide binding 8/1704 74/18639 0.108108108108108 1.18252759802056 0.364412181468449 0.888352864001776 GO:0005539 glycosaminoglycan binding 24/1704 242/18639 0.0991735537190083 1.08479804446514 0.368538272256452 0.888352864001776 GO:0008494 translation activator activity 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0042043 neurexin family protein binding 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0043176 amine binding 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0061783 peptidoglycan muralytic activity 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0070742 C2H2 zinc finger domain binding 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0071933 Arp2/3 complex binding 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0098821 BMP receptor activity 2/1704 14/18639 0.142857142857143 1.56262575452716 0.37072993537082 0.888352864001776 GO:0019205 nucleobase-containing compound kinase activity 5/1704 44/18639 0.113636363636364 1.24299775928297 0.375615844348527 0.896302526284689 GO:0030547 signaling receptor inhibitor activity 5/1704 44/18639 0.113636363636364 1.24299775928297 0.375615844348527 0.896302526284689 GO:0051427 hormone receptor binding 4/1704 34/18639 0.117647058823529 1.28686826843413 0.378048577171226 0.898013958392333 GO:0019957 C-C chemokine binding 3/1704 24/18639 0.125 1.36729753521127 0.37809270864375 0.898013958392333 GO:0003725 double-stranded RNA binding 8/1704 75/18639 0.106666666666667 1.16676056338028 0.378690050695629 0.898013958392333 GO:0120013 lipid transfer activity 7/1704 65/18639 0.107692307692308 1.17797941495125 0.383820132156283 0.908294846904 GO:0008139 nuclear localization sequence binding 3/1704 25/18639 0.12 1.31260563380282 0.403697945215881 0.933531284009269 GO:0008483 transaminase activity 3/1704 25/18639 0.12 1.31260563380282 0.403697945215881 0.933531284009269 GO:0017025 TBP-class protein binding 3/1704 25/18639 0.12 1.31260563380282 0.403697945215881 0.933531284009269 GO:0017056 structural constituent of nuclear pore 3/1704 25/18639 0.12 1.31260563380282 0.403697945215881 0.933531284009269 GO:0120020 cholesterol transfer activity 3/1704 25/18639 0.12 1.31260563380282 0.403697945215881 0.933531284009269 GO:0008252 nucleotidase activity 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0016846 carbon-sulfur lyase activity 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0042809 nuclear vitamin D receptor binding 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0050780 dopamine receptor binding 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0061578 K63-linked deubiquitinase activity 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0120283 protein serine/threonine kinase binding 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0140776 protein-containing complex destabilizing activity 2/1704 15/18639 0.133333333333333 1.45845070422535 0.404390945403582 0.933531284009269 GO:0019212 phosphatase inhibitor activity 6/1704 56/18639 0.107142857142857 1.17196931589537 0.405918677298869 0.933531284009269 GO:0170055 lipid transmembrane transporter activity 6/1704 56/18639 0.107142857142857 1.17196931589537 0.405918677298869 0.933531284009269 GO:0003724 RNA helicase activity 8/1704 77/18639 0.103896103896104 1.13645509420157 0.407319626010418 0.934872153674514 GO:0008083 growth factor activity 16/1704 162/18639 0.0987654320987654 1.08033385498174 0.411314356410208 0.942148916586909 GO:0140030 modification-dependent protein binding 17/1704 173/18639 0.0982658959537572 1.07486973866319 0.414667695352068 0.947930351574828 GO:0004033 aldo-keto reductase (NADPH) activity 4/1704 36/18639 0.111111111111111 1.21537558685446 0.420756906945838 0.949951191929718 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/1704 36/18639 0.111111111111111 1.21537558685446 0.420756906945838 0.949951191929718 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1704 36/18639 0.111111111111111 1.21537558685446 0.420756906945838 0.949951191929718 GO:0003727 single-stranded RNA binding 9/1704 89/18639 0.101123595505618 1.10612834309226 0.427342138399886 0.949951191929718 GO:0008143 poly(A) binding 3/1704 26/18639 0.115384615384615 1.26212080173348 0.428986377376833 0.949951191929718 GO:0008157 protein phosphatase 1 binding 3/1704 26/18639 0.115384615384615 1.26212080173348 0.428986377376833 0.949951191929718 GO:0030247 polysaccharide binding 3/1704 26/18639 0.115384615384615 1.26212080173348 0.428986377376833 0.949951191929718 GO:0030507 spectrin binding 3/1704 26/18639 0.115384615384615 1.26212080173348 0.428986377376833 0.949951191929718 GO:0050681 nuclear androgen receptor binding 3/1704 26/18639 0.115384615384615 1.26212080173348 0.428986377376833 0.949951191929718 GO:0120014 phospholipid transfer activity 3/1704 26/18639 0.115384615384615 1.26212080173348 0.428986377376833 0.949951191929718 GO:0140938 histone H3 methyltransferase activity 5/1704 47/18639 0.106382978723404 1.16365747677555 0.431672584919052 0.949951191929718 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 13/1704 132/18639 0.0984848484848485 1.07726472471191 0.432047429947301 0.949951191929718 GO:0008186 ATP-dependent activity, acting on RNA 8/1704 79/18639 0.10126582278481 1.1076840791585 0.435920727718756 0.949951191929718 GO:0046332 SMAD binding 8/1704 79/18639 0.10126582278481 1.1076840791585 0.435920727718756 0.949951191929718 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 22/1704 229/18639 0.0960698689956332 1.05084876068639 0.436287359640645 0.949951191929718 GO:0003688 DNA replication origin binding 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0005024 transforming growth factor beta receptor activity 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0005149 interleukin-1 receptor binding 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0022858 alanine transmembrane transporter activity 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0043023 ribosomal large subunit binding 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0140328 floppase activity 2/1704 16/18639 0.125 1.36729753521127 0.437160391036773 0.949951191929718 GO:0005506 iron ion binding 15/1704 154/18639 0.0974025974025974 1.06542665081397 0.438245029800123 0.95050107981317 GO:0008080 N-acetyltransferase activity 7/1704 69/18639 0.101449275362319 1.10969075321494 0.445413258922894 0.964218475281945 GO:0004518 nuclease activity 20/1704 209/18639 0.0956937799043062 1.04673495518566 0.449561862940849 0.96717782116901 GO:0051015 actin filament binding 20/1704 209/18639 0.0956937799043062 1.04673495518566 0.449561862940849 0.96717782116901 GO:0032266 phosphatidylinositol-3-phosphate binding 5/1704 48/18639 0.104166666666667 1.13941461267606 0.450153078865876 0.96717782116901 GO:0000049 tRNA binding 8/1704 80/18639 0.1 1.09383802816901 0.450165005128533 0.96717782116901 GO:0005044 scavenger receptor activity 3/1704 27/18639 0.111111111111111 1.21537558685446 0.453878538506055 0.972636218256654 GO:0001786 phosphatidylserine binding 6/1704 59/18639 0.101694915254237 1.1123776557651 0.456109372690784 0.972636218256654 GO:0004879 nuclear receptor activity 6/1704 59/18639 0.101694915254237 1.1123776557651 0.456109372690784 0.972636218256654 GO:0036002 pre-mRNA binding 6/1704 59/18639 0.101694915254237 1.1123776557651 0.456109372690784 0.972636218256654 GO:0043531 ADP binding 4/1704 38/18639 0.105263157894737 1.15140845070423 0.462721982202304 0.984899861559093 GO:0016829 lyase activity 19/1704 200/18639 0.095 1.03914612676056 0.465673908422998 0.985249045763519 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1704 17/18639 0.117647058823529 1.28686826843413 0.468919930792086 0.985249045763519 GO:0004659 prenyltransferase activity 2/1704 17/18639 0.117647058823529 1.28686826843413 0.468919930792086 0.985249045763519 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1704 17/18639 0.117647058823529 1.28686826843413 0.468919930792086 0.985249045763519 GO:0032183 SUMO binding 2/1704 17/18639 0.117647058823529 1.28686826843413 0.468919930792086 0.985249045763519 GO:0038191 neuropilin binding 2/1704 17/18639 0.117647058823529 1.28686826843413 0.468919930792086 0.985249045763519 GO:0070402 NADPH binding 2/1704 17/18639 0.117647058823529 1.28686826843413 0.468919930792086 0.985249045763519 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1704 60/18639 0.1 1.09383802816901 0.472633106834926 0.989413262110477 GO:0098531 ligand-modulated transcription factor activity 6/1704 60/18639 0.1 1.09383802816901 0.472633106834926 0.989413262110477 GO:0019838 growth factor binding 13/1704 136/18639 0.0955882352941176 1.04558046810273 0.475940511827469 0.994515548480433 GO:0005125 cytokine activity 22/1704 234/18639 0.094017094017094 1.02839472733839 0.478084776598486 0.995815567529929 GO:0046875 ephrin receptor binding 3/1704 28/18639 0.107142857142857 1.17196931589537 0.478305115112801 0.995815567529929 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/1704 39/18639 0.102564102564103 1.12188515709642 0.483304258174011 0.999999999999693 GO:0017124 SH3 domain binding 11/1704 115/18639 0.0956521739130435 1.04627985303123 0.484113305104949 0.999999999999693 GO:0005543 phospholipid binding 46/1704 497/18639 0.0925553319919517 1.01240541842605 0.487861335295773 0.999999999999693 GO:0016410 N-acyltransferase activity 9/1704 94/18639 0.0957446808510638 1.04729172909799 0.493790522039059 0.999999999999693 GO:0019783 ubiquitin-like protein peptidase activity 12/1704 127/18639 0.094488188976378 1.03354774315182 0.496864553806932 0.999999999999693 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/1704 18/18639 0.111111111111111 1.21537558685446 0.499580285531165 0.999999999999693 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1704 18/18639 0.111111111111111 1.21537558685446 0.499580285531165 0.999999999999693 GO:0031690 adrenergic receptor binding 2/1704 18/18639 0.111111111111111 1.21537558685446 0.499580285531165 0.999999999999693 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1704 18/18639 0.111111111111111 1.21537558685446 0.499580285531165 0.999999999999693 GO:1901611 phosphatidylglycerol binding 2/1704 18/18639 0.111111111111111 1.21537558685446 0.499580285531165 0.999999999999693 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/1704 29/18639 0.103448275862069 1.1315565808645 0.502206396595965 0.999999999999693 GO:0015036 disulfide oxidoreductase activity 4/1704 40/18639 0.1 1.09383802816901 0.503563783402434 0.999999999999693 GO:0008013 beta-catenin binding 10/1704 106/18639 0.0943396226415094 1.03192266808398 0.507308941597465 0.999999999999693 GO:0140101 catalytic activity, acting on a tRNA 13/1704 139/18639 0.0935251798561151 1.02301398317965 0.508491929552816 0.999999999999693 GO:0060589 nucleoside-triphosphatase regulator activity 45/1704 490/18639 0.0918367346938776 1.00454512791032 0.510587265657877 0.999999999999693 GO:0004896 cytokine receptor activity 9/1704 96/18639 0.09375 1.02547315140845 0.519828810439234 0.999999999999693 GO:0016407 acetyltransferase activity 9/1704 96/18639 0.09375 1.02547315140845 0.519828810439234 0.999999999999693 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/1704 41/18639 0.0975609756097561 1.06715905187221 0.523464052195445 0.999999999999693 GO:0016877 ligase activity, forming carbon-sulfur bonds 4/1704 41/18639 0.0975609756097561 1.06715905187221 0.523464052195445 0.999999999999693 GO:0001965 G-protein alpha-subunit binding 3/1704 30/18639 0.1 1.09383802816901 0.525531682263498 0.999999999999693 GO:0016769 transferase activity, transferring nitrogenous groups 3/1704 30/18639 0.1 1.09383802816901 0.525531682263498 0.999999999999693 GO:0031624 ubiquitin conjugating enzyme binding 3/1704 30/18639 0.1 1.09383802816901 0.525531682263498 0.999999999999693 GO:0048019 receptor antagonist activity 3/1704 30/18639 0.1 1.09383802816901 0.525531682263498 0.999999999999693 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/1704 19/18639 0.105263157894737 1.15140845070423 0.529076918848226 0.999999999999693 GO:0015245 fatty acid transmembrane transporter activity 2/1704 19/18639 0.105263157894737 1.15140845070423 0.529076918848226 0.999999999999693 GO:0046624 sphingolipid transporter activity 2/1704 19/18639 0.105263157894737 1.15140845070423 0.529076918848226 0.999999999999693 GO:0004864 protein phosphatase inhibitor activity 5/1704 53/18639 0.0943396226415094 1.03192266808398 0.539510433336849 0.999999999999693 GO:0034212 protein N-acetyltransferase activity 5/1704 53/18639 0.0943396226415094 1.03192266808398 0.539510433336849 0.999999999999693 GO:0020037 heme binding 13/1704 142/18639 0.0915492957746479 1.00140101170403 0.540504886994334 0.999999999999693 GO:0004402 histone acetyltransferase activity 4/1704 42/18639 0.0952380952380952 1.04175050301811 0.542972749260546 0.999999999999693 GO:0031406 carboxylic acid binding 17/1704 187/18639 0.0909090909090909 0.994398207426376 0.547035106062374 0.999999999999693 GO:0005164 tumor necrosis factor receptor binding 3/1704 31/18639 0.0967741935483871 1.05855293048614 0.548238663336405 0.999999999999693 GO:0017022 myosin binding 7/1704 76/18639 0.0921052631578947 1.0074823943662 0.549648239497572 0.999999999999693 GO:0140597 protein carrier chaperone 17/1704 188/18639 0.0904255319148936 0.989108855259215 0.556199324176938 0.999999999999693 GO:0051287 NAD binding 5/1704 54/18639 0.0925925925925926 1.01281298904538 0.556580954041301 0.999999999999693 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1704 20/18639 0.1 1.09383802816901 0.557366263658771 0.999999999999693 GO:0030627 pre-mRNA 5'-splice site binding 2/1704 20/18639 0.1 1.09383802816901 0.557366263658771 0.999999999999693 GO:0008375 acetylglucosaminyltransferase activity 4/1704 43/18639 0.0930232558139535 1.01752374713397 0.562061594691886 0.999999999999693 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 11/1704 122/18639 0.0901639344262295 0.986247402447472 0.565275304874765 0.999999999999693 GO:0043177 organic acid binding 17/1704 189/18639 0.0899470899470899 0.983875475072658 0.565300186884587 0.999999999999693 GO:1902936 phosphatidylinositol bisphosphate binding 10/1704 111/18639 0.0900900900900901 0.98543966501713 0.567650780010629 0.999999999999693 GO:0030695 GTPase regulator activity 44/1704 489/18639 0.0899795501022495 0.984230536593796 0.568147246202215 0.999999999999693 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 15/1704 167/18639 0.0898203592814371 0.982489246858396 0.568184441008233 0.999999999999693 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/1704 32/18639 0.09375 1.02547315140845 0.570292794297853 0.999999999999693 GO:0120015 sterol transfer activity 3/1704 32/18639 0.09375 1.02547315140845 0.570292794297853 0.999999999999693 GO:0001046 core promoter sequence-specific DNA binding 4/1704 44/18639 0.0909090909090909 0.994398207426376 0.580706169726221 0.999999999999693 GO:0016790 thiolester hydrolase activity 4/1704 44/18639 0.0909090909090909 0.994398207426376 0.580706169726221 0.999999999999693 GO:0043014 alpha-tubulin binding 4/1704 44/18639 0.0909090909090909 0.994398207426376 0.580706169726221 0.999999999999693 GO:0042054 histone methyltransferase activity 6/1704 67/18639 0.0895522388059701 0.979556443136431 0.583052823666671 0.999999999999693 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1704 21/18639 0.0952380952380952 1.04175050301811 0.584422431306421 0.999999999999693 GO:0015125 bile acid transmembrane transporter activity 2/1704 21/18639 0.0952380952380952 1.04175050301811 0.584422431306421 0.999999999999693 GO:0035613 RNA stem-loop binding 2/1704 21/18639 0.0952380952380952 1.04175050301811 0.584422431306421 0.999999999999693 GO:0051428 peptide hormone receptor binding 2/1704 21/18639 0.0952380952380952 1.04175050301811 0.584422431306421 0.999999999999693 GO:0070182 DNA polymerase binding 2/1704 21/18639 0.0952380952380952 1.04175050301811 0.584422431306421 0.999999999999693 GO:0016835 carbon-oxygen lyase activity 7/1704 79/18639 0.0886075949367089 0.969223569263683 0.59170964270135 0.999999999999693 GO:0141108 transporter regulator activity 15/1704 170/18639 0.0882352941176471 0.965151201325601 0.596668874817319 0.999999999999693 GO:0016741 transferase activity, transferring one-carbon groups 19/1704 215/18639 0.0883720930232558 0.966647559777268 0.596850140422881 0.999999999999693 GO:0005548 phospholipid transporter activity 6/1704 68/18639 0.0882352941176471 0.965151201325601 0.597857402841428 0.999999999999693 GO:0008168 methyltransferase activity 18/1704 204/18639 0.0882352941176471 0.965151201325601 0.5988289339788 0.999999999999693 GO:0004715 non-membrane spanning protein tyrosine kinase activity 4/1704 45/18639 0.0888888888888889 0.972300469483568 0.598885727814909 0.999999999999693 GO:0072341 modified amino acid binding 8/1704 91/18639 0.0879120879120879 0.961615848939793 0.599577732144918 0.999999999999693 GO:0004407 histone deacetylase activity 2/1704 22/18639 0.0909090909090909 0.994398207426376 0.610234346577879 0.999999999999693 GO:0008970 phospholipase A1 activity 2/1704 22/18639 0.0909090909090909 0.994398207426376 0.610234346577879 0.999999999999693 GO:0033558 protein lysine deacetylase activity 2/1704 22/18639 0.0909090909090909 0.994398207426376 0.610234346577879 0.999999999999693 GO:0070034 telomerase RNA binding 2/1704 22/18639 0.0909090909090909 0.994398207426376 0.610234346577879 0.999999999999693 GO:0015631 tubulin binding 34/1704 385/18639 0.0883116883116883 0.965986830071337 0.61094768605066 0.999999999999693 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1704 34/18639 0.0882352941176471 0.965151201325601 0.612339383280033 0.999999999999693 GO:0003796 lysozyme activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0004955 prostaglandin receptor activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0005131 growth hormone receptor binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0005381 iron ion transmembrane transporter activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0005528 FK506 binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0008239 dipeptidyl-peptidase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0015279 store-operated calcium channel activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0016868 intramolecular phosphotransferase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0031434 mitogen-activated protein kinase kinase binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0031996 thioesterase binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0032052 bile acid binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0033204 ribonuclease P RNA binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0035256 G protein-coupled glutamate receptor binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0042166 acetylcholine binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0043121 neurotrophin binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0043208 glycosphingolipid binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0043295 glutathione binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0043422 protein kinase B binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0045322 unmethylated CpG binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0050815 phosphoserine residue binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0051864 histone H3K36 demethylase activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0071723 lipopeptide binding 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0141109 transporter activator activity 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1704 10/18639 0.1 1.09383802816901 0.61671626732856 0.999999999999693 GO:0004519 endonuclease activity 11/1704 127/18639 0.0866141732283465 0.947418764555839 0.619929854477879 0.999999999999693 GO:0001664 G protein-coupled receptor binding 26/1704 297/18639 0.0875420875420875 0.957568644188363 0.62215505235816 0.999999999999693 GO:0016782 transferase activity, transferring sulphur-containing groups 6/1704 70/18639 0.0857142857142857 0.937575452716298 0.62659738687078 0.999999999999693 GO:0016229 steroid dehydrogenase activity 3/1704 35/18639 0.0857142857142857 0.937575452716298 0.632295973174198 0.999999999999693 GO:0061733 protein-lysine-acetyltransferase activity 4/1704 47/18639 0.0851063829787234 0.930925981420438 0.63378396342455 0.999999999999693 GO:0003887 DNA-directed DNA polymerase activity 2/1704 23/18639 0.0869565217391304 0.951163502755664 0.634803258325125 0.999999999999693 GO:0005212 structural constituent of eye lens 2/1704 23/18639 0.0869565217391304 0.951163502755664 0.634803258325125 0.999999999999693 GO:0008171 O-methyltransferase activity 2/1704 23/18639 0.0869565217391304 0.951163502755664 0.634803258325125 0.999999999999693 GO:0016493 C-C chemokine receptor activity 2/1704 23/18639 0.0869565217391304 0.951163502755664 0.634803258325125 0.999999999999693 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1704 23/18639 0.0869565217391304 0.951163502755664 0.634803258325125 0.999999999999693 GO:0070888 E-box binding 5/1704 59/18639 0.0847457627118644 0.926981379804249 0.636810361742081 0.999999999999693 GO:0046906 tetrapyrrole binding 13/1704 152/18639 0.0855263157894737 0.935519366197183 0.641165178222159 0.999999999999693 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1704 48/18639 0.0833333333333333 0.911531690140845 0.650477680202611 0.999999999999693 GO:0045505 dynein intermediate chain binding 3/1704 36/18639 0.0833333333333333 0.911531690140845 0.651526797376777 0.999999999999693 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0004954 prostanoid receptor activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0005114 type II transforming growth factor beta receptor binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0005225 volume-sensitive anion channel activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0008526 phosphatidylinositol transfer activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0015217 ADP transmembrane transporter activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0019215 intermediate filament binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0034056 estrogen response element binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0034511 U3 snoRNA binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0034713 type I transforming growth factor beta receptor binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0047676 arachidonate-CoA ligase activity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0048185 activin binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0050998 nitric-oxide synthase binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0097493 structural molecule activity conferring elasticity 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0140031 phosphorylation-dependent protein binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:1900750 oligopeptide binding 1/1704 11/18639 0.0909090909090909 0.994398207426376 0.651775340841477 0.999999999999693 GO:0004527 exonuclease activity 7/1704 84/18639 0.0833333333333333 0.911531690140845 0.657077631515522 0.999999999999693 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0004806 triacylglycerol lipase activity 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0030215 semaphorin receptor binding 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0050431 transforming growth factor beta binding 2/1704 24/18639 0.0833333333333333 0.911531690140845 0.658140581023432 0.999999999999693 GO:0015026 coreceptor activity 5/1704 61/18639 0.0819672131147541 0.89658854767952 0.666264496876978 0.999999999999693 GO:0016836 hydro-lyase activity 5/1704 61/18639 0.0819672131147541 0.89658854767952 0.666264496876978 0.999999999999693 GO:0004521 RNA endonuclease activity 6/1704 73/18639 0.0821917808219178 0.899044954659464 0.667391183133685 0.999999999999693 GO:0005319 lipid transporter activity 15/1704 178/18639 0.0842696629213483 0.921773619243551 0.668261366454461 0.999999999999693 GO:0004386 helicase activity 13/1704 155/18639 0.0838709677419355 0.917412539754657 0.669030168814722 0.999999999999693 GO:0019213 deacetylase activity 3/1704 37/18639 0.0810810810810811 0.886895698515417 0.670027004592234 0.999999999999693 GO:0004540 RNA nuclease activity 10/1704 121/18639 0.0826446280991736 0.903998370387615 0.677570412760072 0.999999999999693 GO:0003707 nuclear steroid receptor activity 2/1704 25/18639 0.08 0.875070422535211 0.680266027615393 0.999999999999693 GO:0005537 D-mannose binding 2/1704 25/18639 0.08 0.875070422535211 0.680266027615393 0.999999999999693 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1704 25/18639 0.08 0.875070422535211 0.680266027615393 0.999999999999693 GO:0047617 fatty acyl-CoA hydrolase activity 2/1704 25/18639 0.08 0.875070422535211 0.680266027615393 0.999999999999693 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/1704 86/18639 0.0813953488372093 0.890333278742221 0.681377125946204 0.999999999999693 GO:0016247 channel regulator activity 14/1704 168/18639 0.0833333333333333 0.911531690140845 0.681555690576327 0.999999999999693 GO:0048020 CCR chemokine receptor binding 4/1704 50/18639 0.08 0.875070422535211 0.682313552467419 0.999999999999693 GO:0008170 N-methyltransferase activity 8/1704 98/18639 0.0816326530612245 0.89292900258695 0.683076398418655 0.999999999999693 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0004000 adenosine deaminase activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0004526 ribonuclease P activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0005078 MAP-kinase scaffold activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0005165 neurotrophin receptor binding 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0005527 macrolide binding 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0015166 polyol transmembrane transporter activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0015269 calcium-activated potassium channel activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0015368 calcium:monoatomic cation antiporter activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0016208 AMP binding 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0016423 tRNA (guanine) methyltransferase activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0016840 carbon-nitrogen lyase activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0035197 siRNA binding 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:1990817 poly(A) RNA polymerase activity 1/1704 12/18639 0.0833333333333333 0.911531690140845 0.683629260704378 0.999999999999693 GO:0000146 microfilament motor activity 3/1704 38/18639 0.0789473684210526 0.863556338028169 0.687796006511371 0.999999999999693 GO:0008081 phosphoric diester hydrolase activity 7/1704 87/18639 0.0804597701149425 0.880099562894609 0.693108674886479 0.999999999999693 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0004435 phosphatidylinositol phospholipase C activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0004950 chemokine receptor activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0005160 transforming growth factor beta receptor binding 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0016289 acyl-CoA hydrolase activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0034237 protein kinase A regulatory subunit binding 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0051139 metal cation:proton antiporter activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0070006 metalloaminopeptidase activity 2/1704 26/18639 0.0769230769230769 0.841413867822319 0.701205998468606 0.999999999999693 GO:0005200 structural constituent of cytoskeleton 9/1704 112/18639 0.0803571428571429 0.878976986921529 0.705725714410158 0.999999999999693 GO:0016779 nucleotidyltransferase activity 11/1704 136/18639 0.0808823529411765 0.884721934548467 0.70872917540174 0.999999999999693 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/1704 52/18639 0.0769230769230769 0.841413867822319 0.712056073656868 0.999999999999693 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0005542 folic acid binding 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0019104 DNA N-glycosylase activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0045159 myosin II binding 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0046974 histone H3K9 methyltransferase activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0046975 histone H3K36 methyltransferase activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0061459 L-arginine transmembrane transporter activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0070700 BMP receptor binding 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0089720 caspase binding 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1704 13/18639 0.0769230769230769 0.841413867822319 0.712570890583572 0.999999999999693 GO:0005085 guanyl-nucleotide exchange factor activity 19/1704 230/18639 0.0826086956521739 0.903605327617881 0.712610892783239 0.999999999999693 GO:0160215 deacylase activity 5/1704 65/18639 0.0769230769230769 0.841413867822319 0.720319467177962 0.999999999999693 GO:0004866 endopeptidase inhibitor activity 13/1704 161/18639 0.0807453416149068 0.883223252558831 0.720931446871943 0.999999999999693 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/1704 27/18639 0.0740740740740741 0.810250391236307 0.72099219526561 0.999999999999693 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/1704 27/18639 0.0740740740740741 0.810250391236307 0.72099219526561 0.999999999999693 GO:0004177 aminopeptidase activity 3/1704 40/18639 0.075 0.820378521126761 0.721156434361407 0.999999999999693 GO:0015144 carbohydrate transmembrane transporter activity 3/1704 40/18639 0.075 0.820378521126761 0.721156434361407 0.999999999999693 GO:0030331 nuclear estrogen receptor binding 3/1704 40/18639 0.075 0.820378521126761 0.721156434361407 0.999999999999693 GO:0016860 intramolecular oxidoreductase activity 4/1704 53/18639 0.0754716981132075 0.82553813446718 0.726141432050339 0.999999999999693 GO:0101005 deubiquitinase activity 9/1704 115/18639 0.0782608695652174 0.856047152480098 0.73486701041224 0.999999999999693 GO:0140767 enzyme-substrate adaptor activity 11/1704 139/18639 0.079136690647482 0.86562721653663 0.735220126653701 0.999999999999693 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1704 41/18639 0.0731707317073171 0.800369288904157 0.736763727690299 0.999999999999693 GO:0004705 JUN kinase activity 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0005161 platelet-derived growth factor receptor binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0005347 ATP transmembrane transporter activity 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0005545 1-phosphatidylinositol binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0008559 ABC-type xenobiotic transporter activity 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0019992 diacylglycerol binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0030983 mismatched DNA binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0031404 chloride ion binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0032036 myosin heavy chain binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0032454 histone H3K9 demethylase activity 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:1901612 cardiolipin binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:1990825 sequence-specific mRNA binding 1/1704 14/18639 0.0714285714285714 0.781312877263582 0.73886634867686 0.999999999999693 GO:0036408 histone H3K14 acetyltransferase activity 2/1704 28/18639 0.0714285714285714 0.781312877263582 0.739660432200442 0.999999999999693 GO:0050698 proteoglycan sulfotransferase activity 2/1704 28/18639 0.0714285714285714 0.781312877263582 0.739660432200442 0.999999999999693 GO:0051959 dynein light intermediate chain binding 2/1704 28/18639 0.0714285714285714 0.781312877263582 0.739660432200442 0.999999999999693 GO:0141052 histone H3 demethylase activity 2/1704 28/18639 0.0714285714285714 0.781312877263582 0.739660432200442 0.999999999999693 GO:0140713 histone chaperone activity 13/1704 164/18639 0.0792682926829268 0.86706672964617 0.744856092481331 0.999999999999693 GO:0008307 structural constituent of muscle 3/1704 42/18639 0.0714285714285714 0.781312877263582 0.751670726031049 0.999999999999693 GO:0005096 GTPase activator activity 22/1704 271/18639 0.0811808118081181 0.887986591133517 0.751973734230742 0.999999999999693 GO:0003774 cytoskeletal motor activity 12/1704 153/18639 0.0784313725490196 0.857912178956089 0.752079622136228 0.999999999999693 GO:0061775 cohesin loader activity 12/1704 153/18639 0.0784313725490196 0.857912178956089 0.752079622136228 0.999999999999693 GO:0032934 sterol binding 5/1704 68/18639 0.0735294117647059 0.804292667771334 0.756552444558466 0.999999999999693 GO:0003785 actin monomer binding 2/1704 29/18639 0.0689655172413793 0.754371053909665 0.757249620022996 0.999999999999693 GO:0004629 phospholipase C activity 2/1704 29/18639 0.0689655172413793 0.754371053909665 0.757249620022996 0.999999999999693 GO:0010484 histone H3 acetyltransferase activity 2/1704 29/18639 0.0689655172413793 0.754371053909665 0.757249620022996 0.999999999999693 GO:0004559 alpha-mannosidase activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0004953 icosanoid receptor activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0008242 omega peptidase activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0010181 FMN binding 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0015250 water channel activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0015929 hexosaminidase activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0017081 chloride channel regulator activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0031005 filamin binding 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0033130 acetylcholine receptor binding 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0034483 heparan sulfate sulfotransferase activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0141050 histone H3K deacetylase activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0141051 histone H4K deacetylase activity 1/1704 15/18639 0.0666666666666667 0.729225352112676 0.762757448910666 0.999999999999693 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1704 43/18639 0.0697674418604651 0.763142810350475 0.765891410881486 0.999999999999693 GO:0042562 hormone binding 7/1704 94/18639 0.074468085106383 0.814560233742883 0.767193844199659 0.999999999999693 GO:0032452 histone demethylase activity 2/1704 30/18639 0.0666666666666667 0.729225352112676 0.773800901291531 0.999999999999693 GO:0033612 receptor serine/threonine kinase binding 2/1704 30/18639 0.0666666666666667 0.729225352112676 0.773800901291531 0.999999999999693 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/1704 30/18639 0.0666666666666667 0.729225352112676 0.773800901291531 0.999999999999693 GO:0043995 histone H4K5 acetyltransferase activity 2/1704 30/18639 0.0666666666666667 0.729225352112676 0.773800901291531 0.999999999999693 GO:0043996 histone H4K8 acetyltransferase activity 2/1704 30/18639 0.0666666666666667 0.729225352112676 0.773800901291531 0.999999999999693 GO:0043997 histone H4K12 acetyltransferase activity 2/1704 30/18639 0.0666666666666667 0.729225352112676 0.773800901291531 0.999999999999693 GO:0008276 protein methyltransferase activity 7/1704 95/18639 0.0736842105263158 0.805985915492958 0.77662342584181 0.999999999999693 GO:0005179 hormone activity 10/1704 132/18639 0.0757575757575758 0.828665172855314 0.777008574000287 0.999999999999693 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1704 70/18639 0.0714285714285714 0.781312877263582 0.778679226192378 0.999999999999693 GO:0016278 lysine N-methyltransferase activity 5/1704 70/18639 0.0714285714285714 0.781312877263582 0.778679226192378 0.999999999999693 GO:0030414 peptidase inhibitor activity 13/1704 169/18639 0.0769230769230769 0.841413867822319 0.781629400177112 0.999999999999693 GO:0030165 PDZ domain binding 6/1704 83/18639 0.072289156626506 0.790726285423384 0.781761576498054 0.999999999999693 GO:0004175 endopeptidase activity 33/1704 405/18639 0.0814814814814815 0.891275430359937 0.78242014042249 0.999999999999693 GO:0000062 fatty-acyl-CoA binding 1/1704 16/18639 0.0625 0.683648767605634 0.784463919435592 0.999999999999693 GO:0004707 MAP kinase activity 1/1704 16/18639 0.0625 0.683648767605634 0.784463919435592 0.999999999999693 GO:0015562 efflux transmembrane transporter activity 1/1704 16/18639 0.0625 0.683648767605634 0.784463919435592 0.999999999999693 GO:0015923 mannosidase activity 1/1704 16/18639 0.0625 0.683648767605634 0.784463919435592 0.999999999999693 GO:0016722 oxidoreductase activity, acting on metal ions 1/1704 16/18639 0.0625 0.683648767605634 0.784463919435592 0.999999999999693 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1704 16/18639 0.0625 0.683648767605634 0.784463919435592 0.999999999999693 GO:0003697 single-stranded DNA binding 9/1704 121/18639 0.0743801652892562 0.813598533348853 0.787109014099099 0.999999999999693 GO:0008327 methyl-CpG binding 2/1704 31/18639 0.0645161290322581 0.705701953657428 0.789356917702229 0.999999999999693 GO:0140457 protein demethylase activity 2/1704 31/18639 0.0645161290322581 0.705701953657428 0.789356917702229 0.999999999999693 GO:0001217 DNA-binding transcription repressor activity 22/1704 278/18639 0.079136690647482 0.86562721653663 0.791622843593105 0.999999999999693 GO:0046915 transition metal ion transmembrane transporter activity 3/1704 45/18639 0.0666666666666667 0.729225352112676 0.792338394954163 0.999999999999693 GO:0140303 intramembrane lipid transporter activity 3/1704 45/18639 0.0666666666666667 0.729225352112676 0.792338394954163 0.999999999999693 GO:0003689 DNA clamp loader activity 12/1704 160/18639 0.075 0.820378521126761 0.803083385640509 0.999999999999693 GO:0099106 ion channel regulator activity 12/1704 160/18639 0.075 0.820378521126761 0.803083385640509 0.999999999999693 GO:0042910 xenobiotic transmembrane transporter activity 2/1704 32/18639 0.0625 0.683648767605634 0.803961192595855 0.999999999999693 GO:0051059 NF-kappaB binding 2/1704 32/18639 0.0625 0.683648767605634 0.803961192595855 0.999999999999693 GO:0004549 tRNA-specific ribonuclease activity 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:0004550 nucleoside diphosphate kinase activity 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:0008484 sulfuric ester hydrolase activity 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:0008569 minus-end-directed microtubule motor activity 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:0016018 cyclosporin A binding 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:0046965 nuclear retinoid X receptor binding 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:1901567 fatty acid derivative binding 1/1704 17/18639 0.0588235294117647 0.643434134217067 0.804185418725811 0.999999999999693 GO:0044325 transmembrane transporter binding 10/1704 136/18639 0.0735294117647059 0.804292667771334 0.807150175134259 0.999999999999693 GO:0140359 ABC-type transporter activity 3/1704 47/18639 0.0638297872340425 0.698194486065328 0.81624697479299 0.999999999999693 GO:0042393 histone binding 19/1704 247/18639 0.0769230769230769 0.841413867822319 0.816595190334995 0.999999999999693 GO:0003684 damaged DNA binding 5/1704 74/18639 0.0675675675675676 0.739079748762847 0.818234129112535 0.999999999999693 GO:0031491 nucleosome binding 5/1704 74/18639 0.0675675675675676 0.739079748762847 0.818234129112535 0.999999999999693 GO:0035064 methylated histone binding 5/1704 74/18639 0.0675675675675676 0.739079748762847 0.818234129112535 0.999999999999693 GO:0005372 water transmembrane transporter activity 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0008308 voltage-gated monoatomic anion channel activity 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0015172 acidic amino acid transmembrane transporter activity 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0016854 racemase and epimerase activity 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0017075 syntaxin-1 binding 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0017128 phospholipid scramblase activity 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/1704 18/18639 0.0555555555555556 0.60768779342723 0.822103367737261 0.999999999999693 GO:0000510 H3-H4 histone complex chaperone activity 11/1704 151/18639 0.0728476821192053 0.796835649659547 0.824751085591786 0.999999999999693 GO:0140584 chromatin extrusion motor activity 11/1704 151/18639 0.0728476821192053 0.796835649659547 0.824751085591786 0.999999999999693 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 11/1704 151/18639 0.0728476821192053 0.796835649659547 0.824751085591786 0.999999999999693 GO:0140849 ATP-dependent H2AZ histone chaperone activity 11/1704 151/18639 0.0728476821192053 0.796835649659547 0.824751085591786 0.999999999999693 GO:0015179 L-amino acid transmembrane transporter activity 4/1704 62/18639 0.0645161290322581 0.705701953657428 0.830315388753562 0.999999999999693 GO:0015035 protein-disulfide reductase activity 2/1704 34/18639 0.0588235294117647 0.643434134217067 0.83049000312782 0.999999999999693 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/1704 34/18639 0.0588235294117647 0.643434134217067 0.83049000312782 0.999999999999693 GO:0015616 DNA translocase activity 11/1704 152/18639 0.0723684210526316 0.791593309859155 0.831041493709643 0.999999999999693 GO:0140674 ATP-dependent histone chaperone activity 11/1704 152/18639 0.0723684210526316 0.791593309859155 0.831041493709643 0.999999999999693 GO:0004713 protein tyrosine kinase activity 10/1704 140/18639 0.0714285714285714 0.781312877263582 0.834149611107166 0.999999999999693 GO:0140034 methylation-dependent protein binding 5/1704 76/18639 0.0657894736842105 0.719630281690141 0.835769225433925 0.999999999999693 GO:0035401 histone H3Y41 kinase activity 8/1704 115/18639 0.0695652173913043 0.760930802204531 0.836090397706717 0.999999999999693 GO:0140801 histone H2AXY142 kinase activity 8/1704 115/18639 0.0695652173913043 0.760930802204531 0.836090397706717 0.999999999999693 GO:0016763 pentosyltransferase activity 3/1704 49/18639 0.0612244897959184 0.669696751940213 0.837774927969171 0.999999999999693 GO:0031490 chromatin DNA binding 9/1704 128/18639 0.0703125 0.769104863556338 0.838036757630768 0.999999999999693 GO:0003756 protein disulfide isomerase activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0008574 plus-end-directed microtubule motor activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0034987 immunoglobulin receptor binding 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0042800 histone H3K4 methyltransferase activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0120227 acyl-CoA binding 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0141147 intracellularly calcium-gated channel activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:1990380 K48-linked deubiquitinase activity 1/1704 19/18639 0.0526315789473684 0.575704225352113 0.838382614897763 0.999999999999693 GO:0008017 microtubule binding 21/1704 276/18639 0.0760869565217391 0.832268064911206 0.840527039032849 0.999999999999693 GO:0010485 histone H4 acetyltransferase activity 2/1704 35/18639 0.0571428571428571 0.625050301810865 0.842501762518949 0.999999999999693 GO:0034061 DNA polymerase activity 2/1704 35/18639 0.0571428571428571 0.625050301810865 0.842501762518949 0.999999999999693 GO:0043015 gamma-tubulin binding 2/1704 35/18639 0.0571428571428571 0.625050301810865 0.842501762518949 0.999999999999693 GO:0106310 protein serine kinase activity 28/1704 361/18639 0.0775623268698061 0.848406226834692 0.845301587284739 0.999999999999693 GO:0032813 tumor necrosis factor receptor superfamily binding 3/1704 50/18639 0.06 0.656302816901408 0.847697994490559 0.999999999999693 GO:0004674 protein serine/threonine kinase activity 34/1704 433/18639 0.0785219399538106 0.858902839670819 0.848191632674028 0.999999999999693 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 9/1704 130/18639 0.0692307692307692 0.757272481040087 0.850695692260231 0.999999999999693 GO:0052745 inositol phosphate phosphatase activity 1/1704 20/18639 0.05 0.546919014084507 0.853172949173499 0.999999999999693 GO:0061608 nuclear import signal receptor activity 1/1704 20/18639 0.05 0.546919014084507 0.853172949173499 0.999999999999693 GO:0004190 aspartic-type endopeptidase activity 2/1704 36/18639 0.0555555555555556 0.60768779342723 0.8537355839979 0.999999999999693 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 20/1704 268/18639 0.0746268656716418 0.816297035947025 0.85842125871834 0.999999999999693 GO:0004497 monooxygenase activity 7/1704 106/18639 0.0660377358490566 0.722345867658783 0.862228223996429 0.999999999999693 GO:0022829 wide pore channel activity 2/1704 37/18639 0.0540540540540541 0.591263799010278 0.864233217106795 0.999999999999693 GO:0070001 aspartic-type peptidase activity 2/1704 37/18639 0.0540540540540541 0.591263799010278 0.864233217106795 0.999999999999693 GO:0140658 ATP-dependent chromatin remodeler activity 11/1704 158/18639 0.069620253164557 0.761532804421465 0.865212842363054 0.999999999999693 GO:0015174 basic amino acid transmembrane transporter activity 1/1704 21/18639 0.0476190476190476 0.520875251509054 0.866610475066853 0.999999999999693 GO:0051010 microtubule plus-end binding 1/1704 21/18639 0.0476190476190476 0.520875251509054 0.866610475066853 0.999999999999693 GO:0061891 calcium ion sensor activity 1/1704 21/18639 0.0476190476190476 0.520875251509054 0.866610475066853 0.999999999999693 GO:1904047 S-adenosyl-L-methionine binding 1/1704 21/18639 0.0476190476190476 0.520875251509054 0.866610475066853 0.999999999999693 GO:0016500 protein-hormone receptor activity 4/1704 67/18639 0.0597014925373134 0.65303762875762 0.872361386766506 0.999999999999693 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1704 67/18639 0.0597014925373134 0.65303762875762 0.872361386766506 0.999999999999693 GO:0035091 phosphatidylinositol binding 21/1704 284/18639 0.073943661971831 0.808823894068637 0.873583558351523 0.999999999999693 GO:1901981 phosphatidylinositol phosphate binding 13/1704 185/18639 0.0702702702702703 0.768642938713361 0.873739255071902 0.999999999999693 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/1704 38/18639 0.0526315789473684 0.575704225352113 0.874035284362097 0.999999999999693 GO:0005544 calcium-dependent phospholipid binding 3/1704 53/18639 0.0566037735849057 0.619153600850385 0.874357824491303 0.999999999999693 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/1704 53/18639 0.0566037735849057 0.619153600850385 0.874357824491303 0.999999999999693 GO:0004843 cysteine-type deubiquitinase activity 7/1704 108/18639 0.0648148148148148 0.708969092331768 0.874479114248097 0.999999999999693 GO:0008093 cytoskeletal anchor activity 1/1704 22/18639 0.0454545454545455 0.497199103713188 0.878818862137757 0.999999999999693 GO:0016881 acid-amino acid ligase activity 1/1704 22/18639 0.0454545454545455 0.497199103713188 0.878818862137757 0.999999999999693 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/1704 22/18639 0.0454545454545455 0.497199103713188 0.878818862137757 0.999999999999693 GO:0140784 metal ion sensor activity 1/1704 22/18639 0.0454545454545455 0.497199103713188 0.878818862137757 0.999999999999693 GO:0003777 microtubule motor activity 4/1704 68/18639 0.0588235294117647 0.643434134217067 0.879599445654508 0.999999999999693 GO:0015485 cholesterol binding 3/1704 54/18639 0.0555555555555556 0.60768779342723 0.882278504150141 0.999999999999693 GO:0140097 catalytic activity, acting on DNA 25/1704 336/18639 0.0744047619047619 0.813867580482897 0.884956471421657 0.999999999999693 GO:0016279 protein-lysine N-methyltransferase activity 4/1704 69/18639 0.0579710144927536 0.63410900183711 0.886478412299745 0.999999999999693 GO:0098632 cell-cell adhesion mediator activity 3/1704 55/18639 0.0545454545454545 0.596638924455826 0.889750999327631 0.999999999999693 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0005283 amino acid:sodium symporter activity 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0017134 fibroblast growth factor binding 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0031681 G-protein beta-subunit binding 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0070577 lysine-acetylated histone binding 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0071617 lysophospholipid acyltransferase activity 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0140103 catalytic activity, acting on a glycoprotein 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1704 23/18639 0.0434782608695652 0.475581751377832 0.889910480492876 0.999999999999693 GO:0004532 RNA exonuclease activity 2/1704 40/18639 0.05 0.546919014084507 0.89170875435204 0.999999999999693 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/1704 40/18639 0.05 0.546919014084507 0.89170875435204 0.999999999999693 GO:0032451 demethylase activity 2/1704 40/18639 0.05 0.546919014084507 0.89170875435204 0.999999999999693 GO:0071855 neuropeptide receptor binding 2/1704 40/18639 0.05 0.546919014084507 0.89170875435204 0.999999999999693 GO:0042626 ATPase-coupled transmembrane transporter activity 6/1704 98/18639 0.0612244897959184 0.669696751940213 0.893883416886949 0.999999999999693 GO:0140299 molecular sensor activity 4/1704 71/18639 0.0563380281690141 0.616246776433247 0.899212608718774 0.999999999999693 GO:0001727 lipid kinase activity 2/1704 41/18639 0.0487804878048781 0.533579525936104 0.899654653155206 0.999999999999693 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1704 41/18639 0.0487804878048781 0.533579525936104 0.899654653155206 0.999999999999693 GO:0017080 sodium channel regulator activity 2/1704 41/18639 0.0487804878048781 0.533579525936104 0.899654653155206 0.999999999999693 GO:0005540 hyaluronic acid binding 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0015149 hexose transmembrane transporter activity 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0015295 solute:proton symporter activity 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0030552 cAMP binding 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0050699 WW domain binding 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0055056 D-glucose transmembrane transporter activity 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0140033 acetylation-dependent protein binding 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0140612 DNA damage sensor activity 1/1704 24/18639 0.0416666666666667 0.455765845070423 0.899987432643722 0.999999999999693 GO:0050660 flavin adenine dinucleotide binding 5/1704 86/18639 0.0581395348837209 0.635952341958729 0.903756743409691 0.999999999999693 GO:0016874 ligase activity 11/1704 167/18639 0.0658682634730539 0.720492114362824 0.905898350812183 0.999999999999693 GO:0016853 isomerase activity 12/1704 180/18639 0.0666666666666667 0.729225352112676 0.906055513289734 0.999999999999693 GO:0004520 DNA endonuclease activity 2/1704 42/18639 0.0476190476190476 0.520875251509054 0.907053849511414 0.999999999999693 GO:0016887 ATP hydrolysis activity 31/1704 417/18639 0.0743405275779376 0.813164960988955 0.907997948750258 0.999999999999693 GO:0000030 mannosyltransferase activity 1/1704 25/18639 0.04 0.437535211267606 0.909142491186569 0.999999999999693 GO:0004709 MAP kinase kinase kinase activity 1/1704 25/18639 0.04 0.437535211267606 0.909142491186569 0.999999999999693 GO:0008408 3'-5' exonuclease activity 3/1704 58/18639 0.0517241379310345 0.565778290432249 0.909681210228344 0.999999999999693 GO:0140996 histone H3 kinase activity 26/1704 357/18639 0.0728291316526611 0.796632737602083 0.910669064185944 0.999999999999693 GO:0008238 exopeptidase activity 6/1704 102/18639 0.0588235294117647 0.643434134217067 0.913789888286708 0.999999999999693 GO:0035402 histone H3T11 kinase activity 17/1704 247/18639 0.0688259109311741 0.752843986998917 0.916379497596944 0.999999999999693 GO:0035403 histone H3T6 kinase activity 17/1704 247/18639 0.0688259109311741 0.752843986998917 0.916379497596944 0.999999999999693 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1704 130/18639 0.0615384615384615 0.673131094257855 0.916489894456314 0.999999999999693 GO:0005112 Notch binding 1/1704 26/18639 0.0384615384615385 0.420706933911159 0.917459950895288 0.999999999999693 GO:0005227 calcium-activated cation channel activity 1/1704 26/18639 0.0384615384615385 0.420706933911159 0.917459950895288 0.999999999999693 GO:0015145 monosaccharide transmembrane transporter activity 1/1704 26/18639 0.0384615384615385 0.420706933911159 0.917459950895288 0.999999999999693 GO:0015216 purine nucleotide transmembrane transporter activity 1/1704 26/18639 0.0384615384615385 0.420706933911159 0.917459950895288 0.999999999999693 GO:0052742 phosphatidylinositol kinase activity 1/1704 26/18639 0.0384615384615385 0.420706933911159 0.917459950895288 0.999999999999693 GO:0035173 histone kinase activity 26/1704 360/18639 0.0722222222222222 0.789994131455399 0.918251694459305 0.999999999999693 GO:0005385 zinc ion transmembrane transporter activity 1/1704 27/18639 0.037037037037037 0.405125195618153 0.92501640303489 0.999999999999693 GO:0008266 poly(U) RNA binding 1/1704 27/18639 0.037037037037037 0.405125195618153 0.92501640303489 0.999999999999693 GO:0008395 steroid hydroxylase activity 1/1704 27/18639 0.037037037037037 0.405125195618153 0.92501640303489 0.999999999999693 GO:0015252 proton channel activity 1/1704 27/18639 0.037037037037037 0.405125195618153 0.92501640303489 0.999999999999693 GO:0098631 cell adhesion mediator activity 4/1704 76/18639 0.0526315789473684 0.575704225352113 0.925685384261506 0.999999999999693 GO:0004180 carboxypeptidase activity 2/1704 46/18639 0.0434782608695652 0.475581751377832 0.931829995707971 0.999999999999693 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 2/1704 46/18639 0.0434782608695652 0.475581751377832 0.931829995707971 0.999999999999693 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/1704 46/18639 0.0434782608695652 0.475581751377832 0.931829995707971 0.999999999999693 GO:0016866 intramolecular transferase activity 1/1704 28/18639 0.0357142857142857 0.390656438631791 0.931881438991722 0.999999999999693 GO:0045499 chemorepellent activity 1/1704 28/18639 0.0357142857142857 0.390656438631791 0.931881438991722 0.999999999999693 GO:0051119 sugar transmembrane transporter activity 1/1704 28/18639 0.0357142857142857 0.390656438631791 0.931881438991722 0.999999999999693 GO:0019199 transmembrane receptor protein kinase activity 4/1704 78/18639 0.0512820512820513 0.560942578548212 0.934391718617431 0.999999999999693 GO:0051213 dioxygenase activity 5/1704 93/18639 0.0537634408602151 0.58808496138119 0.935363621101788 0.999999999999693 GO:0004252 serine-type endopeptidase activity 11/1704 176/18639 0.0625 0.683648767605634 0.935788569595241 0.999999999999693 GO:0004181 metallocarboxypeptidase activity 1/1704 29/18639 0.0344827586206897 0.377185526954832 0.938118289669176 0.999999999999693 GO:0005416 amino acid:monoatomic cation symporter activity 1/1704 29/18639 0.0344827586206897 0.377185526954832 0.938118289669176 0.999999999999693 GO:0035250 UDP-galactosyltransferase activity 1/1704 29/18639 0.0344827586206897 0.377185526954832 0.938118289669176 0.999999999999693 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 16/1704 243/18639 0.065843621399177 0.720222569987828 0.939463028492268 0.999999999999693 GO:0004867 serine-type endopeptidase inhibitor activity 5/1704 95/18639 0.0526315789473684 0.575704225352113 0.942499903163689 0.999999999999693 GO:0008187 poly-pyrimidine tract binding 1/1704 30/18639 0.0333333333333333 0.364612676056338 0.943784406509785 0.999999999999693 GO:0015215 nucleotide transmembrane transporter activity 1/1704 30/18639 0.0333333333333333 0.364612676056338 0.943784406509785 0.999999999999693 GO:0022839 monoatomic ion-gated channel activity 1/1704 30/18639 0.0333333333333333 0.364612676056338 0.943784406509785 0.999999999999693 GO:0051721 protein phosphatase 2A binding 1/1704 30/18639 0.0333333333333333 0.364612676056338 0.943784406509785 0.999999999999693 GO:0004676 3-phosphoinositide-dependent protein kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0004711 ribosomal protein S6 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0035175 histone H3S10 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0035979 histone H2AXS139 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0044022 histone H3S28 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0044023 histone H4S1 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0044024 histone H2AS1 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0044025 histone H2BS14 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0072354 histone H3T3 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0072371 histone H2AS121 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0072518 Rho-dependent protein serine/threonine kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0140823 histone H2BS36 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0140855 histone H3S57 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0140995 histone H2A kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0140997 histone H4 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0140998 histone H2B kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:1990244 histone H2AT120 kinase activity 16/1704 245/18639 0.0653061224489796 0.71434320206956 0.943929454320189 0.999999999999693 GO:0015101 organic cation transmembrane transporter activity 4/1704 81/18639 0.0493827160493827 0.540166927490871 0.94572465481397 0.999999999999693 GO:0004677 DNA-dependent protein kinase activity 16/1704 246/18639 0.0650406504065041 0.711439367914806 0.946054570938173 0.999999999999693 GO:0140857 histone H3T45 kinase activity 16/1704 246/18639 0.0650406504065041 0.711439367914806 0.946054570938173 0.999999999999693 GO:0008235 metalloexopeptidase activity 3/1704 66/18639 0.0454545454545455 0.497199103713188 0.947850034346514 0.999999999999693 GO:0005184 neuropeptide hormone activity 1/1704 31/18639 0.032258064516129 0.352850976828714 0.948931989470037 0.999999999999693 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1704 31/18639 0.032258064516129 0.352850976828714 0.948931989470037 0.999999999999693 GO:0016411 acylglycerol O-acyltransferase activity 1/1704 31/18639 0.032258064516129 0.352850976828714 0.948931989470037 0.999999999999693 GO:0017147 Wnt-protein binding 1/1704 31/18639 0.032258064516129 0.352850976828714 0.948931989470037 0.999999999999693 GO:0005201 extracellular matrix structural constituent 10/1704 168/18639 0.0595238095238095 0.651094064386318 0.949871452708531 0.999999999999693 GO:0004679 AMP-activated protein kinase activity 16/1704 248/18639 0.0645161290322581 0.705701953657428 0.950097455961371 0.999999999999693 GO:0015605 organophosphate ester transmembrane transporter activity 2/1704 50/18639 0.04 0.437535211267606 0.950261612913254 0.999999999999693 GO:0008094 ATP-dependent activity, acting on DNA 13/1704 210/18639 0.0619047619047619 0.677137826961771 0.95321414906919 0.999999999999693 GO:0008378 galactosyltransferase activity 1/1704 32/18639 0.03125 0.341824383802817 0.953608466788559 0.999999999999693 GO:0043425 bHLH transcription factor binding 1/1704 32/18639 0.03125 0.341824383802817 0.953608466788559 0.999999999999693 GO:0140142 nucleocytoplasmic carrier activity 1/1704 32/18639 0.03125 0.341824383802817 0.953608466788559 0.999999999999693 GO:0160041 neuropeptide activity 1/1704 32/18639 0.03125 0.341824383802817 0.953608466788559 0.999999999999693 GO:0005021 vascular endothelial growth factor receptor activity 2/1704 51/18639 0.0392156862745098 0.428956089478045 0.954064590149745 0.999999999999693 GO:0016597 amino acid binding 2/1704 51/18639 0.0392156862745098 0.428956089478045 0.954064590149745 0.999999999999693 GO:0141003 histone H2AX kinase activity 24/1704 354/18639 0.0677966101694915 0.741585103843399 0.955418188864241 0.999999999999693 GO:0017171 serine hydrolase activity 12/1704 198/18639 0.0606060606060606 0.662932138284251 0.956010789362446 0.999999999999693 GO:0019239 deaminase activity 1/1704 33/18639 0.0303030303030303 0.331466069142126 0.957856930946795 0.999999999999693 GO:0042923 neuropeptide binding 1/1704 33/18639 0.0303030303030303 0.331466069142126 0.957856930946795 0.999999999999693 GO:0008146 sulfotransferase activity 2/1704 53/18639 0.0377358490566038 0.41276906723359 0.960852390965543 0.999999999999693 GO:0038064 collagen receptor activity 2/1704 53/18639 0.0377358490566038 0.41276906723359 0.960852390965543 0.999999999999693 GO:0051018 protein kinase A binding 2/1704 53/18639 0.0377358490566038 0.41276906723359 0.960852390965543 0.999999999999693 GO:0015020 glucuronosyltransferase activity 1/1704 34/18639 0.0294117647058824 0.321717067108534 0.961716534820097 0.999999999999693 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1704 34/18639 0.0294117647058824 0.321717067108534 0.961716534820097 0.999999999999693 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1704 34/18639 0.0294117647058824 0.321717067108534 0.961716534820097 0.999999999999693 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/1704 54/18639 0.037037037037037 0.405125195618153 0.963874463535366 0.999999999999693 GO:0000287 magnesium ion binding 14/1704 230/18639 0.0608695652173913 0.665814451928965 0.964760150633185 0.999999999999693 GO:0000175 3'-5'-RNA exonuclease activity 1/1704 35/18639 0.0285714285714286 0.312525150905433 0.965222851652484 0.999999999999693 GO:0005343 organic acid:sodium symporter activity 1/1704 35/18639 0.0285714285714286 0.312525150905433 0.965222851652484 0.999999999999693 GO:0008374 O-acyltransferase activity 2/1704 55/18639 0.0363636363636364 0.397759282970551 0.966671575392262 0.999999999999693 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1704 36/18639 0.0277777777777778 0.303843896713615 0.9684082021569 0.999999999999693 GO:0030170 pyridoxal phosphate binding 2/1704 56/18639 0.0357142857142857 0.390656438631791 0.969259570571554 0.999999999999693 GO:0003678 DNA helicase activity 3/1704 74/18639 0.0405405405405405 0.443447849257708 0.970534793073984 0.999999999999693 GO:0030280 structural constituent of skin epidermis 1/1704 37/18639 0.027027027027027 0.295631899505139 0.971301951741625 0.999999999999693 GO:0030551 cyclic nucleotide binding 1/1704 37/18639 0.027027027027027 0.295631899505139 0.971301951741625 0.999999999999693 GO:0042805 actinin binding 1/1704 37/18639 0.027027027027027 0.295631899505139 0.971301951741625 0.999999999999693 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/1704 57/18639 0.0350877192982456 0.383802816901408 0.971653278418718 0.999999999999693 GO:0070279 vitamin B6 binding 2/1704 57/18639 0.0350877192982456 0.383802816901408 0.971653278418718 0.999999999999693 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/1704 91/18639 0.043956043956044 0.480807924469896 0.971765250937204 0.999999999999693 GO:0008236 serine-type peptidase activity 11/1704 194/18639 0.0567010309278351 0.620217438652534 0.971901887390282 0.999999999999693 GO:0005109 frizzled binding 1/1704 38/18639 0.0263157894736842 0.287852112676056 0.973930780589721 0.999999999999693 GO:0042887 amide transmembrane transporter activity 1/1704 38/18639 0.0263157894736842 0.287852112676056 0.973930780589721 0.999999999999693 GO:0005496 steroid binding 5/1704 108/18639 0.0462962962962963 0.506406494522692 0.973945960095283 0.999999999999693 GO:0000217 DNA secondary structure binding 1/1704 39/18639 0.0256410256410256 0.280471289274106 0.976318929069647 0.999999999999693 GO:0008237 metallopeptidase activity 10/1704 184/18639 0.0543478260869565 0.59447718922229 0.977004003783552 0.999999999999693 GO:0004222 metalloendopeptidase activity 5/1704 110/18639 0.0454545454545455 0.497199103713188 0.977034241229609 0.999999999999693 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/1704 60/18639 0.0333333333333333 0.364612676056338 0.9778028550075 0.999999999999693 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/1704 60/18639 0.0333333333333333 0.364612676056338 0.9778028550075 0.999999999999693 GO:0071949 FAD binding 1/1704 40/18639 0.025 0.273459507042254 0.978488420729073 0.999999999999693 GO:0004812 aminoacyl-tRNA ligase activity 1/1704 41/18639 0.024390243902439 0.266789762968052 0.98045926491842 0.999999999999693 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1704 41/18639 0.024390243902439 0.266789762968052 0.98045926491842 0.999999999999693 GO:0046943 carboxylic acid transmembrane transporter activity 10/1704 188/18639 0.0531914893617021 0.581828738387773 0.981251282748605 0.999999999999693 GO:0022804 active transmembrane transporter activity 30/1704 457/18639 0.0656455142231947 0.718055598360403 0.981911566421963 0.999999999999693 GO:0005342 organic acid transmembrane transporter activity 10/1704 189/18639 0.0529100529100529 0.578750279454505 0.982194174220413 0.999999999999693 GO:0019894 kinesin binding 1/1704 42/18639 0.0238095238095238 0.260437625754527 0.982249640903957 0.999999999999693 GO:0005262 calcium channel activity 6/1704 131/18639 0.0458015267175573 0.500994516718632 0.983617105354073 0.999999999999693 GO:0015085 calcium ion transmembrane transporter activity 7/1704 147/18639 0.0476190476190476 0.520875251509054 0.984254098684959 0.999999999999693 GO:0015171 amino acid transmembrane transporter activity 4/1704 102/18639 0.0392156862745098 0.428956089478045 0.986685441998448 0.999999999999693 GO:0030276 clathrin binding 1/1704 46/18639 0.0217391304347826 0.237790875688916 0.987914946653942 0.999999999999693 GO:0061749 forked DNA-dependent helicase activity 1/1704 47/18639 0.0212765957446809 0.232731495355109 0.989022510301641 0.999999999999693 GO:0099095 ligand-gated monoatomic anion channel activity 1/1704 47/18639 0.0212765957446809 0.232731495355109 0.989022510301641 0.999999999999693 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1704 47/18639 0.0212765957446809 0.232731495355109 0.989022510301641 0.999999999999693 GO:0009378 four-way junction helicase activity 1/1704 48/18639 0.0208333333333333 0.227882922535211 0.990028622739572 0.999999999999693 GO:0036121 double-stranded DNA helicase activity 1/1704 48/18639 0.0208333333333333 0.227882922535211 0.990028622739572 0.999999999999693 GO:0043138 3'-5' DNA helicase activity 1/1704 48/18639 0.0208333333333333 0.227882922535211 0.990028622739572 0.999999999999693 GO:0005004 GPI-linked ephrin receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0005008 hepatocyte growth factor receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0005009 insulin receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0005011 macrophage colony-stimulating factor receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0005020 stem cell factor receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0008288 boss receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0036332 placental growth factor receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0038062 protein tyrosine kinase collagen receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0060175 brain-derived neurotrophic factor receptor activity 1/1704 49/18639 0.0204081632653061 0.223232250646738 0.990942571792972 0.999999999999693 GO:0005006 epidermal growth factor receptor activity 1/1704 50/18639 0.02 0.218767605633803 0.991772795443579 0.999999999999693 GO:0005007 fibroblast growth factor receptor activity 1/1704 50/18639 0.02 0.218767605633803 0.991772795443579 0.999999999999693 GO:0005017 platelet-derived growth factor receptor activity 1/1704 50/18639 0.02 0.218767605633803 0.991772795443579 0.999999999999693 GO:0005019 platelet-derived growth factor beta-receptor activity 1/1704 50/18639 0.02 0.218767605633803 0.991772795443579 0.999999999999693 GO:0043178 alcohol binding 3/1704 92/18639 0.0326086956521739 0.356686313533374 0.992330582736365 0.999999999999693 GO:0005010 insulin-like growth factor receptor activity 1/1704 51/18639 0.0196078431372549 0.214478044739022 0.992526959549456 0.999999999999693 GO:0005030 neurotrophin receptor activity 1/1704 51/18639 0.0196078431372549 0.214478044739022 0.992526959549456 0.999999999999693 GO:0008194 UDP-glycosyltransferase activity 6/1704 145/18639 0.0413793103448276 0.452622632345799 0.993206516425614 0.999999999999693 GO:0005003 ephrin receptor activity 1/1704 53/18639 0.0188679245283019 0.206384533616795 0.993834329182063 0.999999999999693 GO:0005005 transmembrane-ephrin receptor activity 1/1704 53/18639 0.0188679245283019 0.206384533616795 0.993834329182063 0.999999999999693 GO:0017046 peptide hormone binding 1/1704 53/18639 0.0188679245283019 0.206384533616795 0.993834329182063 0.999999999999693 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/1704 181/18639 0.0441988950276243 0.483464321842658 0.994776603239706 0.999999999999693 GO:0015297 antiporter activity 5/1704 135/18639 0.037037037037037 0.405125195618153 0.995625419972612 0.999999999999693 GO:0017116 single-stranded DNA helicase activity 1/1704 58/18639 0.0172413793103448 0.188592763477416 0.996188055574635 0.999999999999693 GO:0015459 potassium channel regulator activity 1/1704 59/18639 0.0169491525423729 0.18539627596085 0.99653763596863 0.999999999999693 GO:0005253 monoatomic anion channel activity 3/1704 103/18639 0.029126213592233 0.318593600437577 0.996738807306085 0.999999999999693 GO:0005254 chloride channel activity 2/1704 83/18639 0.0240963855421687 0.263575428474461 0.996772586146007 0.999999999999693 GO:0008528 G protein-coupled peptide receptor activity 4/1704 122/18639 0.0327868852459016 0.358635419071808 0.996835069889733 0.999999999999693 GO:1901682 sulfur compound transmembrane transporter activity 1/1704 63/18639 0.0158730158730159 0.173625083836351 0.99764357407061 0.999999999999693 GO:0001653 peptide receptor activity 4/1704 128/18639 0.03125 0.341824383802817 0.997972951439276 0.999999999999693 GO:0003730 mRNA 3'-UTR binding 12/1704 262/18639 0.0458015267175573 0.500994516718632 0.99829687542892 0.999999999999693 GO:0019842 vitamin binding 5/1704 150/18639 0.0333333333333333 0.364612676056338 0.998476329016398 0.999999999999693 GO:0008514 organic anion transmembrane transporter activity 12/1704 269/18639 0.0446096654275093 0.487957484685062 0.998856015745646 0.999999999999693 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1704 73/18639 0.0136986301369863 0.149840825776577 0.999099899208379 0.999999999999693 GO:0016758 hexosyltransferase activity 7/1704 197/18639 0.0355329949238579 0.388673411024523 0.999342540564616 0.999999999999693 GO:0015370 solute:sodium symporter activity 1/1704 79/18639 0.0126582278481013 0.138460509894812 0.999494873548865 0.999999999999693 GO:0099094 ligand-gated monoatomic cation channel activity 3/1704 136/18639 0.0220588235294118 0.2412878003314 0.999774159067739 0.999999999999693 GO:0016757 glycosyltransferase activity 10/1704 267/18639 0.0374531835205993 0.409677164108245 0.999816160102386 0.999999999999693 GO:0015294 solute:monoatomic cation symporter activity 2/1704 116/18639 0.0172413793103448 0.188592763477416 0.999818061836779 0.999999999999693 GO:0015108 chloride transmembrane transporter activity 2/1704 121/18639 0.0165289256198347 0.180799674077523 0.9998832165229 0.999999999999693 GO:0005267 potassium channel activity 2/1704 124/18639 0.0161290322580645 0.176425488414357 0.999910562376209 0.999999999999693 GO:0005249 voltage-gated potassium channel activity 1/1704 98/18639 0.0102040816326531 0.111616125323369 0.999919025216959 0.999999999999693 GO:0008509 monoatomic anion transmembrane transporter activity 3/1704 149/18639 0.0201342281879195 0.220235844597788 0.999923645281801 0.999999999999693 GO:0015276 ligand-gated monoatomic ion channel activity 4/1704 186/18639 0.021505376344086 0.235233984552476 0.999978570925207 0.999999999999693 GO:0015103 inorganic anion transmembrane transporter activity 3/1704 165/18639 0.0181818181818182 0.198879641485275 0.99998028599211 0.999999999999693 GO:0022834 ligand-gated channel activity 4/1704 188/18639 0.0212765957446809 0.232731495355109 0.999981793755037 0.999999999999693 GO:0022843 voltage-gated monoatomic cation channel activity 2/1704 143/18639 0.013986013986014 0.152984339604058 0.999983686762714 0.999999999999693 GO:0015291 secondary active transmembrane transporter activity 9/1704 287/18639 0.0313588850174216 0.343015409530353 0.999985008660805 0.999999999999693 GO:0015293 symporter activity 2/1704 146/18639 0.0136986301369863 0.149840825776577 0.999987551397361 0.999999999999693 GO:0005244 voltage-gated monoatomic ion channel activity 3/1704 173/18639 0.0173410404624277 0.189682895058211 0.999990052505412 0.999999999999693 GO:0022832 voltage-gated channel activity 3/1704 175/18639 0.0171428571428571 0.18751509054326 0.999991621614872 0.999999999999693 GO:0045182 translation regulator activity 12/1704 356/18639 0.0337078651685393 0.36870944769742 0.999995059341513 0.999999999999693 GO:0015079 potassium ion transmembrane transporter activity 2/1704 160/18639 0.0125 0.136729753521127 0.999996493714428 0.999999999999693 GO:0015081 sodium ion transmembrane transporter activity 2/1704 164/18639 0.0121951219512195 0.133394881484026 0.999997562321957 0.999999999999693 GO:0005261 monoatomic cation channel activity 10/1704 341/18639 0.0293255131964809 0.320773615298831 0.999998814903941 0.999999999999693 GO:0005216 monoatomic ion channel activity 13/1704 448/18639 0.0290178571428571 0.31740835638833 0.999999971037799 0.999999999999693 GO:0046873 metal ion transmembrane transporter activity 13/1704 450/18639 0.0288888888888889 0.31599765258216 0.999999974889878 0.999999999999693 GO:0022836 gated channel activity 6/1704 318/18639 0.0188679245283019 0.206384533616795 0.999999984818043 0.999999999999693 GO:0030371 translation repressor activity 6/1704 329/18639 0.0182370820668693 0.199484138875808 0.99999999386193 0.999999999999693 GO:1903231 mRNA base-pairing translational repressor activity 1/1704 298/18639 0.00335570469798658 0.0367059740996313 0.999999999999693 0.999999999999693