ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140375 immune receptor activity 49/1556 156/18639 0.314102564102564 3.76256921099466 1.01073074334125e-16 1.17143693153251e-13 GO:0023023 MHC protein complex binding 20/1556 37/18639 0.540540540540541 6.47502258042104 9.57392585157222e-13 5.5480900309861e-10 GO:0042277 peptide binding 57/1556 249/18639 0.228915662650602 2.74213305664819 1.47401729812346e-12 5.69462016175031e-10 GO:0042605 peptide antigen binding 21/1556 45/18639 0.466666666666667 5.5901028277635 1.05469780458627e-11 3.0559868887887e-09 GO:0023026 MHC class II protein complex binding 16/1556 27/18639 0.592592592592593 7.09854327335047 2.77473235779658e-11 6.43182960537248e-09 GO:0038187 pattern recognition receptor activity 20/1556 48/18639 0.416666666666667 4.99116323907455 4.10875742891337e-10 7.93674976685099e-08 GO:0038024 cargo receptor activity 22/1556 65/18639 0.338461538461538 4.05436029266363 5.9036503852877e-09 9.77475828078349e-07 GO:0003779 actin binding 73/1556 443/18639 0.164785553047404 1.97393182728185 1.35574517742547e-08 1.96413582579514e-06 GO:0019955 cytokine binding 34/1556 144/18639 0.236111111111111 2.82832583547558 2.06174856046315e-08 2.65507397952977e-06 GO:0005126 cytokine receptor binding 51/1556 275/18639 0.185454545454545 2.22152138350082 4.7652277619917e-08 5.52289897614838e-06 GO:0035325 Toll-like receptor binding 9/1556 13/18639 0.692307692307692 8.29300968953925 1.01062565014272e-07 1.06483193501401e-05 GO:0001540 amyloid-beta binding 23/1556 83/18639 0.27710843373494 3.31942422646886 1.82239061203746e-07 1.76012559945951e-05 GO:0005178 integrin binding 33/1556 161/18639 0.204968944099379 2.45528030145779 1.10337531519362e-06 9.83701531007233e-05 GO:0030246 carbohydrate binding 48/1556 280/18639 0.171428571428571 2.05350716121924 1.29144103134343e-06 0.000106912868237646 GO:0001618 virus receptor activity 21/1556 81/18639 0.259259259259259 3.10561268209083 2.03324844793021e-06 0.000157102330076741 GO:0140272 exogenous protein binding 21/1556 82/18639 0.25609756097561 3.06773935669948 2.52031290283302e-06 0.000177071881500728 GO:0032395 MHC class II receptor activity 7/1556 10/18639 0.7 8.38515424164524 2.67073831809064e-06 0.000177071881500728 GO:0005543 phospholipid binding 72/1556 497/18639 0.144869215291751 1.73535816441063 2.75003784901907e-06 0.000177071881500728 GO:0004896 cytokine receptor activity 23/1556 96/18639 0.239583333333333 2.86991886246787 2.95806347442487e-06 0.000180441871939917 GO:0030228 lipoprotein particle receptor activity 9/1556 18/18639 0.5 5.98939588688946 4.66946778415018e-06 0.000270595658091503 GO:0005044 scavenger receptor activity 11/1556 27/18639 0.407407407407407 4.88024850042845 4.91459687288958e-06 0.000271238941699001 GO:0030695 GTPase regulator activity 70/1556 489/18639 0.143149284253579 1.71475546863911 5.74396265042202e-06 0.000291974107095689 GO:0060589 nucleoside-triphosphatase regulator activity 70/1556 490/18639 0.142857142857143 1.7112559676827 6.16830930002718e-06 0.000291974107095689 GO:0002020 protease binding 28/1556 136/18639 0.205882352941176 2.46622183577801 6.4108591630644e-06 0.000291974107095689 GO:0005096 GTPase activator activity 45/1556 271/18639 0.166051660516605 1.98909826501864 6.51593796159309e-06 0.000291974107095689 GO:0044389 ubiquitin-like protein ligase binding 51/1556 322/18639 0.158385093167702 1.89726205112648 6.54989368808275e-06 0.000291974107095689 GO:0019864 IgG binding 7/1556 11/18639 0.636363636363636 7.62286749240477 6.81220381375995e-06 0.00029242015630177 GO:0016798 hydrolase activity, acting on glycosyl bonds 27/1556 130/18639 0.207692307692308 2.48790290686178 7.85690860135707e-06 0.000325219895320459 GO:0031267 small GTPase binding 46/1556 283/18639 0.162544169611307 1.94708276181565 9.20369872814318e-06 0.000367830580204067 GO:0140297 DNA-binding transcription factor binding 68/1556 488/18639 0.139344262295082 1.66917590290362 1.91076591448077e-05 0.000738192564961069 GO:0046332 SMAD binding 19/1556 79/18639 0.240506329113924 2.88097523673164 1.98429796132512e-05 0.000741871399088972 GO:0019865 immunoglobulin binding 10/1556 26/18639 0.384615384615385 4.60722760529958 2.4397354409107e-05 0.000883641680004844 GO:0043394 proteoglycan binding 12/1556 37/18639 0.324324324324324 3.88501354825262 2.8239992344885e-05 0.000991822761446113 GO:0140313 molecular sequestering activity 15/1556 55/18639 0.272727272727273 3.26694321103061 3.01197107342416e-05 0.00100944303537946 GO:0017154 semaphorin receptor activity 7/1556 13/18639 0.538461538461538 6.45011864741942 3.04836119398458e-05 0.00100944303537946 GO:0051020 GTPase binding 48/1556 315/18639 0.152380952380952 1.82533969886155 3.38098235574901e-05 0.00108848848619809 GO:0004857 enzyme inhibitor activity 59/1556 416/18639 0.141826923076923 1.69891517945422 4.0035694176921e-05 0.00125409106894734 GO:0140311 protein sequestering activity 11/1556 33/18639 0.333333333333333 3.99293059125964 4.56371906025876e-05 0.00139193431337892 GO:0032393 MHC class I receptor activity 8/1556 18/18639 0.444444444444444 5.32390745501285 4.73041316879572e-05 0.0014057817596498 GO:0031625 ubiquitin protein ligase binding 46/1556 302/18639 0.152317880794702 1.82458417746301 4.93396956183678e-05 0.00142961768054221 GO:0051015 actin filament binding 35/1556 209/18639 0.167464114832536 2.00601776115915 5.56761927967934e-05 0.00157387091345082 GO:0042625 ATPase-coupled ion transmembrane transporter activity 9/1556 24/18639 0.375 4.4920469151671 7.91563510140634e-05 0.00208505024602954 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 9/1556 24/18639 0.375 4.4920469151671 7.91563510140634e-05 0.00208505024602954 GO:0046961 proton-transporting ATPase activity, rotational mechanism 9/1556 24/18639 0.375 4.4920469151671 7.91563510140634e-05 0.00208505024602954 GO:0008238 exopeptidase activity 21/1556 102/18639 0.205882352941176 2.46622183577801 8.85359764857173e-05 0.00228029326104325 GO:0005041 low-density lipoprotein particle receptor activity 7/1556 15/18639 0.466666666666667 5.5901028277635 9.8412015404841e-05 0.00245029687251351 GO:0001968 fibronectin binding 10/1556 30/18639 0.333333333333333 3.99293059125964 0.000101238987793588 0.00245029687251351 GO:0022853 active monoatomic ion transmembrane transporter activity 23/1556 118/18639 0.194915254237288 2.33484924404165 0.000101479076687358 0.00245029687251351 GO:0042608 T cell receptor binding 6/1556 11/18639 0.545454545454545 6.53388642206123 0.000107206136872585 0.00253575331908829 GO:0061134 peptidase regulator activity 36/1556 226/18639 0.15929203539823 1.90812612325682 0.000126340168116619 0.00292856509694323 GO:0061135 endopeptidase regulator activity 31/1556 184/18639 0.168478260869565 2.01816600536493 0.000128922501356949 0.00292982704064126 GO:0033218 amide binding 38/1556 247/18639 0.153846153846154 1.84289104211983 0.000174646886521545 0.00389261041304751 GO:0071813 lipoprotein particle binding 10/1556 32/18639 0.3125 3.74337242930591 0.000186260274561177 0.00399769737437787 GO:0071814 protein-lipid complex binding 10/1556 32/18639 0.3125 3.74337242930591 0.000186260274561177 0.00399769737437787 GO:0004875 complement receptor activity 6/1556 12/18639 0.5 5.98939588688946 0.000199246484133623 0.00419866682019763 GO:0003823 antigen binding 29/1556 174/18639 0.166666666666667 1.99646529562982 0.000253167571282124 0.00511870720272172 GO:0008429 phosphatidylethanolamine binding 7/1556 17/18639 0.411764705882353 4.93244367155603 0.000256156184433011 0.00511870720272172 GO:0030169 low-density lipoprotein particle binding 7/1556 17/18639 0.411764705882353 4.93244367155603 0.000256156184433011 0.00511870720272172 GO:0015399 primary active transmembrane transporter activity 28/1556 166/18639 0.168674698795181 2.02051909437235 0.000261757570450331 0.00514198346020227 GO:0050840 extracellular matrix binding 15/1556 67/18639 0.223880597014925 2.6818190538311 0.000337636941073463 0.00652202024506905 GO:0032396 inhibitory MHC class I receptor activity 6/1556 13/18639 0.461538461538462 5.5286731263595 0.000343900374585433 0.00653410711712323 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 13/1556 54/18639 0.240740740740741 2.88378320479863 0.000391733989773196 0.00724032134776897 GO:0035091 phosphatidylinositol binding 41/1556 284/18639 0.144366197183099 1.72933261522865 0.000393563628049565 0.00724032134776897 GO:0042287 MHC protein binding 11/1556 41/18639 0.268292682926829 3.21382218320898 0.000399851703435167 0.00724106444189623 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 18/1556 91/18639 0.197802197802198 2.36943133986836 0.000460794836918407 0.00821632639982206 GO:0019207 kinase regulator activity 41/1556 287/18639 0.142857142857143 1.7112559676827 0.00048949286364676 0.0085149331278595 GO:0070851 growth factor receptor binding 24/1556 139/18639 0.172661870503597 2.06828059403377 0.000492235133362025 0.0085149331278595 GO:0019763 immunoglobulin receptor activity 6/1556 14/18639 0.428571428571429 5.13376790304811 0.000559401742522833 0.00953450911152887 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 47/1556 349/18639 0.134670487106017 1.61318972311636 0.000751774920605827 0.012404991208769 GO:0005518 collagen binding 15/1556 72/18639 0.208333333333333 2.49558161953727 0.000759926122366348 0.012404991208769 GO:0042379 chemokine receptor binding 15/1556 72/18639 0.208333333333333 2.49558161953727 0.000759926122366348 0.012404991208769 GO:0030414 peptidase inhibitor activity 27/1556 169/18639 0.159763313609467 1.91377146681675 0.000798793312621501 0.0128583534628933 GO:0042288 MHC class I protein binding 7/1556 20/18639 0.35 4.19257712082262 0.000816746900170805 0.0129672555794242 GO:0004866 endopeptidase inhibitor activity 26/1556 161/18639 0.161490683229814 1.93446326781523 0.000839937570111784 0.0131552384291832 GO:0015929 hexosaminidase activity 6/1556 15/18639 0.4 4.79151670951157 0.000866728227268164 0.013393840205384 GO:0004715 non-membrane spanning protein tyrosine kinase activity 11/1556 45/18639 0.244444444444444 2.92814910025707 0.00094247632571727 0.0141861046948872 GO:0008009 chemokine activity 11/1556 45/18639 0.244444444444444 2.92814910025707 0.00094247632571727 0.0141861046948872 GO:0005539 glycosaminoglycan binding 35/1556 242/18639 0.144628099173554 1.73246988463745 0.0009772245707734 0.0145205548400817 GO:0019956 chemokine binding 9/1556 33/18639 0.272727272727273 3.26694321103061 0.0011744871099066 0.0172307665871107 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 6/1556 16/18639 0.375 4.4920469151671 0.00128935164870355 0.018448871121573 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 6/1556 16/18639 0.375 4.4920469151671 0.00128935164870355 0.018448871121573 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 10/1556 40/18639 0.25 2.99469794344473 0.00132281683594069 0.0186968867421373 GO:0015026 coreceptor activity 13/1556 61/18639 0.213114754098361 2.55285726326436 0.0013420589216792 0.0187403167497131 GO:0001784 phosphotyrosine residue binding 11/1556 47/18639 0.234042553191489 2.80354701088443 0.0013856965744058 0.019119313449242 GO:0009055 electron transfer activity 20/1556 116/18639 0.172413793103448 2.06530892651361 0.00142283742130534 0.0194008067210929 GO:0015078 proton transmembrane transporter activity 28/1556 185/18639 0.151351351351351 1.81300632251789 0.0015132316118445 0.0203934353270672 GO:0033691 sialic acid binding 7/1556 22/18639 0.318181818181818 3.81143374620238 0.00154921800842831 0.0206384330088323 GO:0051019 mitogen-activated protein kinase binding 8/1556 28/18639 0.285714285714286 3.42251193536541 0.00157894750104332 0.02079545629215 GO:0001530 lipopolysaccharide binding 10/1556 41/18639 0.24390243902439 2.92165653018998 0.0016205475238457 0.020869050890413 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 10/1556 41/18639 0.24390243902439 2.92165653018998 0.0016205475238457 0.020869050890413 GO:0019903 protein phosphatase binding 23/1556 144/18639 0.159722222222222 1.91327924164524 0.00188625883939165 0.0240238900533508 GO:0035497 cAMP response element binding 5/1556 12/18639 0.416666666666667 4.99116323907455 0.00193649214335081 0.0241332730553074 GO:0070008 serine-type exopeptidase activity 5/1556 12/18639 0.416666666666667 4.99116323907455 0.00193649214335081 0.0241332730553074 GO:0019838 growth factor binding 22/1556 136/18639 0.161764705882353 1.9377457281113 0.00198484698030795 0.0244727409593289 GO:0051861 glycolipid binding 8/1556 29/18639 0.275862068965517 3.30449428242177 0.00202289400872278 0.0246793069064179 GO:0005125 cytokine activity 33/1556 234/18639 0.141025641025641 1.68931678860985 0.00204652242357833 0.0247074946763259 GO:0019902 phosphatase binding 28/1556 190/18639 0.147368421052632 1.76529562982005 0.00226181408721019 0.0270251806915114 GO:0004197 cysteine-type endopeptidase activity 16/1556 88/18639 0.181818181818182 2.17796214068708 0.00235034195577055 0.027796391089164 GO:0019887 protein kinase regulator activity 35/1556 255/18639 0.137254901960784 1.64414789051868 0.00242852066530772 0.0284308631423399 GO:0003924 GTPase activity 43/1556 331/18639 0.129909365558912 1.55615723949394 0.00247893825368113 0.0287308943601643 GO:0016854 racemase and epimerase activity 6/1556 18/18639 0.333333333333333 3.99293059125964 0.00258483819845947 0.0293708575687699 GO:0034185 apolipoprotein binding 6/1556 18/18639 0.333333333333333 3.99293059125964 0.00258483819845947 0.0293708575687699 GO:0019209 kinase activator activity 23/1556 148/18639 0.155405405405405 1.86156899187105 0.00270957769175779 0.030489325677158 GO:0008235 metalloexopeptidase activity 13/1556 66/18639 0.196969696969697 2.35945898574433 0.0028305394807806 0.0315441851752377 GO:0042626 ATPase-coupled transmembrane transporter activity 17/1556 98/18639 0.173469387755102 2.07795367504328 0.00293060809785773 0.0318121736046051 GO:0008035 high-density lipoprotein particle binding 5/1556 13/18639 0.384615384615385 4.60722760529958 0.00293186199882916 0.0318121736046051 GO:0005085 guanyl-nucleotide exchange factor activity 32/1556 230/18639 0.139130434782609 1.6666145076562 0.00293693060888072 0.0318121736046051 GO:0017124 SH3 domain binding 19/1556 115/18639 0.165217391304348 1.97910472784173 0.00305131482805909 0.0327310820125634 GO:1901981 phosphatidylinositol phosphate binding 27/1556 185/18639 0.145945945945946 1.74825609671368 0.00307824671213927 0.0327310820125634 GO:0120020 cholesterol transfer activity 7/1556 25/18639 0.28 3.3540616966581 0.00349886240835585 0.0368652866480402 GO:0032934 sterol binding 13/1556 68/18639 0.191176470588235 2.29006313322244 0.00371675534049572 0.0388082832399508 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 9/1556 39/18639 0.230769230769231 2.76433656317975 0.00409693262447823 0.0423959367122345 GO:0051219 phosphoprotein binding 16/1556 93/18639 0.172043010752688 2.06086740194046 0.004170172270283 0.042771943904938 GO:0005161 platelet-derived growth factor receptor binding 5/1556 14/18639 0.357142857142857 4.27813991920676 0.0042498954745549 0.0428315552609489 GO:0008191 metalloendopeptidase inhibitor activity 5/1556 14/18639 0.357142857142857 4.27813991920676 0.0042498954745549 0.0428315552609489 GO:0044325 transmembrane transporter binding 21/1556 136/18639 0.154411764705882 1.84966637683351 0.00436723704423012 0.0433222380930798 GO:0015485 cholesterol binding 11/1556 54/18639 0.203703703703704 2.44012425021422 0.00444446392449432 0.0433222380930798 GO:0030247 polysaccharide binding 7/1556 26/18639 0.269230769230769 3.22505932370971 0.00444809864803839 0.0433222380930798 GO:0070006 metalloaminopeptidase activity 7/1556 26/18639 0.269230769230769 3.22505932370971 0.00444809864803839 0.0433222380930798 GO:0001216 DNA-binding transcription activator activity 58/1556 491/18639 0.118126272912424 1.4150100262305 0.00451049168550735 0.0435638321958585 GO:0016004 phospholipase activator activity 6/1556 20/18639 0.3 3.59363753213368 0.00466984513351531 0.0447301695020185 GO:0016209 antioxidant activity 15/1556 86/18639 0.174418604651163 2.08932414658935 0.00476597291421112 0.0452767426850057 GO:0030296 protein tyrosine kinase activator activity 8/1556 33/18639 0.242424242424242 2.9039495209161 0.00485243275746099 0.045723329804043 GO:0004177 aminopeptidase activity 9/1556 40/18639 0.225 2.69522814910026 0.00490232107921493 0.0458208881516944 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 57/1556 484/18639 0.117768595041322 1.41072547749049 0.0051563474718631 0.0478096537591146 GO:0008237 metallopeptidase activity 26/1556 184/18639 0.141304347826087 1.69265535933833 0.00560491258550864 0.0514972798990149 GO:0030295 protein kinase activator activity 21/1556 139/18639 0.151079136690647 1.80974551977955 0.00564292885864961 0.0514972798990149 GO:0031072 heat shock protein binding 20/1556 131/18639 0.152671755725191 1.8288231715693 0.00604952045165856 0.0546507033055299 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 6/1556 21/18639 0.285714285714286 3.42251193536541 0.00608277888387692 0.0546507033055299 GO:0004713 protein tyrosine kinase activity 21/1556 140/18639 0.15 1.79681876606684 0.00613081118165754 0.0546585396887776 GO:0016763 pentosyltransferase activity 10/1556 49/18639 0.204081632653061 2.44465138240386 0.00645497572396315 0.0571092890387274 GO:0016175 superoxide-generating NAD(P)H oxidase activity 4/1556 10/18639 0.4 4.79151670951157 0.00674142680940068 0.058746719339063 GO:0071723 lipopeptide binding 4/1556 10/18639 0.4 4.79151670951157 0.00674142680940068 0.058746719339063 GO:0042056 chemoattractant activity 9/1556 42/18639 0.214285714285714 2.56688395152405 0.00687668768747114 0.0594782166401422 GO:0048020 CCR chemokine receptor binding 10/1556 50/18639 0.2 2.39575835475578 0.00747913047740508 0.0642097201726851 GO:0141108 transporter regulator activity 24/1556 170/18639 0.141176470588235 1.69112354453349 0.00765470829145975 0.0652338743367783 GO:0048029 monosaccharide binding 13/1556 74/18639 0.175675675675676 2.10438233863684 0.00778839071335476 0.0658886484436363 GO:0005496 steroid binding 17/1556 108/18639 0.157407407407407 1.88555055698372 0.00802766099391026 0.0671726589880654 GO:0005149 interleukin-1 receptor binding 5/1556 16/18639 0.3125 3.74337242930591 0.00805608248433226 0.0671726589880654 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 7/1556 29/18639 0.241379310344828 2.89143249711905 0.0084688076218099 0.0701096288119834 GO:0008201 heparin binding 24/1556 172/18639 0.13953488372093 1.67145931727148 0.00881961141982475 0.0723470192573843 GO:0045309 protein phosphorylated amino acid binding 11/1556 59/18639 0.186440677966102 2.2333340595181 0.00886391435250092 0.0723470192573843 GO:0043178 alcohol binding 15/1556 92/18639 0.16304347826087 1.95306387615961 0.0089694945135067 0.0726968121759039 GO:0001664 G protein-coupled receptor binding 37/1556 297/18639 0.124579124579125 1.492307392693 0.00924381776566205 0.0743998943777938 GO:0004602 glutathione peroxidase activity 6/1556 23/18639 0.260869565217391 3.12490220185537 0.00979979951973397 0.0770130894997087 GO:0001851 complement component C3b binding 4/1556 11/18639 0.363636363636364 4.35592428137415 0.00990073368029042 0.0770130894997087 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 4/1556 11/18639 0.363636363636364 4.35592428137415 0.00990073368029042 0.0770130894997087 GO:0047676 arachidonate-CoA ligase activity 4/1556 11/18639 0.363636363636364 4.35592428137415 0.00990073368029042 0.0770130894997087 GO:0050786 RAGE receptor binding 4/1556 11/18639 0.363636363636364 4.35592428137415 0.00990073368029042 0.0770130894997087 GO:0030145 manganese ion binding 12/1556 68/18639 0.176470588235294 2.11390443066687 0.00997862555541454 0.0771015134581696 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 5/1556 17/18639 0.294117647058824 3.52317405111145 0.0106407365148736 0.0811356159259115 GO:0036041 long-chain fatty acid binding 5/1556 17/18639 0.294117647058824 3.52317405111145 0.0106407365148736 0.0811356159259115 GO:0141110 transporter inhibitor activity 9/1556 45/18639 0.2 2.39575835475578 0.0109114203173026 0.082655791815384 GO:0060229 lipase activator activity 6/1556 24/18639 0.25 2.99469794344473 0.0121624129617383 0.0915340040432122 GO:0004180 carboxypeptidase activity 9/1556 46/18639 0.195652173913043 2.34367665139153 0.0125871334535037 0.0941192753071661 GO:0008081 phosphoric diester hydrolase activity 14/1556 87/18639 0.160919540229885 1.92762166474603 0.012680105325074 0.0942066799471843 GO:0070064 proline-rich region binding 5/1556 18/18639 0.277777777777778 3.32744215938303 0.0137391589442637 0.0999393062491495 GO:0099106 ion channel regulator activity 22/1556 160/18639 0.1375 1.6470838688946 0.0138628753028629 0.0999393062491495 GO:0004126 cytidine deaminase activity 4/1556 12/18639 0.333333333333333 3.99293059125964 0.0138828544487602 0.0999393062491495 GO:0035259 nuclear glucocorticoid receptor binding 4/1556 12/18639 0.333333333333333 3.99293059125964 0.0138828544487602 0.0999393062491495 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 4/1556 12/18639 0.333333333333333 3.99293059125964 0.0138828544487602 0.0999393062491495 GO:0005507 copper ion binding 11/1556 63/18639 0.174603174603175 2.09153507161219 0.0143807421055347 0.102723312811757 GO:0005504 fatty acid binding 9/1556 47/18639 0.191489361702128 2.29381119072362 0.0144468507233101 0.102723312811757 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/1556 32/18639 0.21875 2.62036070051414 0.0146712244480505 0.103054237183579 GO:0120015 sterol transfer activity 7/1556 32/18639 0.21875 2.62036070051414 0.0146712244480505 0.103054237183579 GO:0001848 complement binding 6/1556 25/18639 0.24 2.87491002570694 0.0148982710312275 0.103395785180794 GO:0005537 D-mannose binding 6/1556 25/18639 0.24 2.87491002570694 0.0148982710312275 0.103395785180794 GO:0005525 GTP binding 44/1556 378/18639 0.116402116402116 1.39435671440813 0.0154522272084112 0.106601972229456 GO:0061791 GTPase motor activity 8/1556 40/18639 0.2 2.39575835475578 0.015992020635231 0.109027952448428 GO:1990606 membrane scission GTPase motor activity 8/1556 40/18639 0.2 2.39575835475578 0.015992020635231 0.109027952448428 GO:0170055 lipid transmembrane transporter activity 10/1556 56/18639 0.178571428571429 2.13906995960338 0.0164731175995648 0.10996365043676 GO:0140693 molecular condensate scaffold activity 9/1556 48/18639 0.1875 2.24602345758355 0.0165015632555833 0.10996365043676 GO:0019001 guanyl nucleotide binding 46/1556 400/18639 0.115 1.37756105398458 0.0165087792717828 0.10996365043676 GO:0032561 guanyl ribonucleotide binding 46/1556 400/18639 0.115 1.37756105398458 0.0165087792717828 0.10996365043676 GO:0071889 14-3-3 protein binding 7/1556 33/18639 0.212121212121212 2.54095583080159 0.0173147452878245 0.113237109888274 GO:0140416 transcription regulator inhibitor activity 7/1556 33/18639 0.212121212121212 2.54095583080159 0.0173147452878245 0.113237109888274 GO:0015245 fatty acid transmembrane transporter activity 5/1556 19/18639 0.263157894736842 3.15231362467866 0.0173910315445322 0.113237109888274 GO:0097001 ceramide binding 5/1556 19/18639 0.263157894736842 3.15231362467866 0.0173910315445322 0.113237109888274 GO:0001637 G protein-coupled chemoattractant receptor activity 6/1556 26/18639 0.230769230769231 2.76433656317975 0.0180333227461842 0.114838577268283 GO:0004950 chemokine receptor activity 6/1556 26/18639 0.230769230769231 2.76433656317975 0.0180333227461842 0.114838577268283 GO:0008198 ferrous iron binding 6/1556 26/18639 0.230769230769231 2.76433656317975 0.0180333227461842 0.114838577268283 GO:0070412 R-SMAD binding 6/1556 26/18639 0.230769230769231 2.76433656317975 0.0180333227461842 0.114838577268283 GO:0042169 SH2 domain binding 8/1556 41/18639 0.195121951219512 2.33732522415198 0.0184566753609446 0.116892277285982 GO:0005035 death receptor activity 4/1556 13/18639 0.307692307692308 3.68578208423967 0.0187499622042851 0.11746597943117 GO:0071714 icosanoid transmembrane transporter activity 4/1556 13/18639 0.307692307692308 3.68578208423967 0.0187499622042851 0.11746597943117 GO:0004175 endopeptidase activity 46/1556 405/18639 0.11358024691358 1.36055412739217 0.0201426065748273 0.125409065355135 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 7/1556 34/18639 0.205882352941176 2.46622183577801 0.0202767281882288 0.125409065355135 GO:0022804 active transmembrane transporter activity 51/1556 457/18639 0.111597374179431 1.3368017077959 0.0203424540869416 0.125409065355135 GO:0003725 double-stranded RNA binding 12/1556 75/18639 0.16 1.91660668380463 0.0209544895037072 0.128498694893104 GO:0004860 protein kinase inhibitor activity 13/1556 84/18639 0.154761904761905 1.85386063165626 0.0215610378876739 0.130577207865811 GO:0001614 purinergic nucleotide receptor activity 5/1556 20/18639 0.25 2.99469794344473 0.0216314270148712 0.130577207865811 GO:0016502 nucleotide receptor activity 5/1556 20/18639 0.25 2.99469794344473 0.0216314270148712 0.130577207865811 GO:0016298 lipase activity 18/1556 130/18639 0.138461538461538 1.65860193790785 0.0228389356894371 0.137151950590972 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 10/1556 59/18639 0.169491525423729 2.030303690471 0.0231976155266477 0.137905284418758 GO:0016247 channel regulator activity 22/1556 168/18639 0.130952380952381 1.56865130370914 0.0232023558771853 0.137905284418758 GO:0016229 steroid dehydrogenase activity 7/1556 35/18639 0.2 2.39575835475578 0.0235739711180787 0.139399145540068 GO:0005319 lipid transporter activity 23/1556 178/18639 0.129213483146067 1.54782140897143 0.023759591159942 0.139440525860361 GO:0016830 carbon-carbon lyase activity 9/1556 51/18639 0.176470588235294 2.11390443066687 0.0239419021969041 0.139440525860361 GO:0030544 Hsp70 protein binding 9/1556 51/18639 0.176470588235294 2.11390443066687 0.0239419021969041 0.139440525860361 GO:0008200 ion channel inhibitor activity 8/1556 43/18639 0.186046511627907 2.22861242302864 0.0241788593005128 0.139477632993478 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 11/1556 68/18639 0.161764705882353 1.9377457281113 0.0245071030412838 0.139477632993478 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 4/1556 14/18639 0.285714285714286 3.42251193536541 0.0245499888961773 0.139477632993478 GO:0044548 S100 protein binding 4/1556 14/18639 0.285714285714286 3.42251193536541 0.0245499888961773 0.139477632993478 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 4/1556 14/18639 0.285714285714286 3.42251193536541 0.0245499888961773 0.139477632993478 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 17/1556 122/18639 0.139344262295082 1.66917590290362 0.0250105949752393 0.141401363786841 GO:0001217 DNA-binding transcription repressor activity 33/1556 278/18639 0.118705035971223 1.42194290839822 0.0253881547472493 0.142839181320689 GO:0046625 sphingolipid binding 6/1556 28/18639 0.214285714285714 2.56688395152405 0.0255948615722027 0.143306495469482 GO:0001846 opsonin binding 5/1556 21/18639 0.238095238095238 2.85209327947117 0.0264903795558069 0.146901195718565 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 5/1556 21/18639 0.238095238095238 2.85209327947117 0.0264903795558069 0.146901195718565 GO:0005080 protein kinase C binding 9/1556 52/18639 0.173076923076923 2.07325242238481 0.0268811036164533 0.148358090911759 GO:0016248 channel inhibitor activity 8/1556 44/18639 0.181818181818182 2.17796214068708 0.0274611442911372 0.150841072196341 GO:0035401 histone H3Y41 kinase activity 16/1556 115/18639 0.139130434782609 1.6666145076562 0.0294317037693606 0.160147158068962 GO:0140801 histone H2AXY142 kinase activity 16/1556 115/18639 0.139130434782609 1.6666145076562 0.0294317037693606 0.160147158068962 GO:0051087 protein-folding chaperone binding 18/1556 134/18639 0.134328358208955 1.60909143229866 0.0299630557092115 0.162057998807126 GO:0043236 laminin binding 6/1556 29/18639 0.206896551724138 2.47837071181633 0.0300625278201313 0.162057998807126 GO:0033293 monocarboxylic acid binding 12/1556 79/18639 0.151898734177215 1.81956330740946 0.0302972072328083 0.162566959179744 GO:0004467 long-chain fatty acid-CoA ligase activity 4/1556 15/18639 0.266666666666667 3.19434447300771 0.0313167197318059 0.165735516754169 GO:0017081 chloride channel regulator activity 4/1556 15/18639 0.266666666666667 3.19434447300771 0.0313167197318059 0.165735516754169 GO:0050700 CARD domain binding 4/1556 15/18639 0.266666666666667 3.19434447300771 0.0313167197318059 0.165735516754169 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 5/1556 22/18639 0.227272727272727 2.72245267585884 0.0319925899509941 0.167780143679648 GO:0061133 endopeptidase activator activity 5/1556 22/18639 0.227272727272727 2.72245267585884 0.0319925899509941 0.167780143679648 GO:0140996 histone H3 kinase activity 40/1556 357/18639 0.112044817927171 1.34216154328055 0.0345268748001383 0.180255170690812 GO:0001965 G-protein alpha-subunit binding 6/1556 30/18639 0.2 2.39575835475578 0.0350113304340936 0.181152374879975 GO:0035925 mRNA 3'-UTR AU-rich region binding 6/1556 30/18639 0.2 2.39575835475578 0.0350113304340936 0.181152374879975 GO:0043531 ADP binding 7/1556 38/18639 0.184210526315789 2.20661953727506 0.0356263565537302 0.183515321092326 GO:0019210 kinase inhibitor activity 13/1556 90/18639 0.144444444444444 1.73026992287918 0.0357869514333944 0.183526888103115 GO:0015085 calcium ion transmembrane transporter activity 19/1556 147/18639 0.129251700680272 1.54827920885578 0.037187435495546 0.188444595907736 GO:0008374 O-acyltransferase activity 9/1556 55/18639 0.163636363636364 1.96016592661837 0.037204483487425 0.188444595907736 GO:0004620 phospholipase activity 15/1556 109/18639 0.137614678899083 1.64845758354756 0.0372336604511403 0.188444595907736 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 5/1556 23/18639 0.217391304347826 2.60408516821281 0.0381572539596775 0.190621798876147 GO:0042171 lysophosphatidic acid acyltransferase activity 5/1556 23/18639 0.217391304347826 2.60408516821281 0.0381572539596775 0.190621798876147 GO:0071617 lysophospholipid acyltransferase activity 5/1556 23/18639 0.217391304347826 2.60408516821281 0.0381572539596775 0.190621798876147 GO:0035173 histone kinase activity 40/1556 360/18639 0.111111111111111 1.33097686375321 0.0386246753715188 0.191110673740494 GO:0072341 modified amino acid binding 13/1556 91/18639 0.142857142857143 1.7112559676827 0.0386878944302163 0.191110673740494 GO:0005324 long-chain fatty acid transmembrane transporter activity 4/1556 16/18639 0.25 2.99469794344473 0.0390702654809638 0.191110673740494 GO:0055102 lipase inhibitor activity 4/1556 16/18639 0.25 2.99469794344473 0.0390702654809638 0.191110673740494 GO:0008234 cysteine-type peptidase activity 23/1556 187/18639 0.122994652406417 1.47332733046479 0.0390795769426203 0.191110673740494 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 31/1556 268/18639 0.115671641791045 1.38560651114607 0.0399970856723746 0.194775723925555 GO:0005164 tumor necrosis factor receptor binding 6/1556 31/18639 0.193548387096774 2.31847582718302 0.0404552526518324 0.19520530273952 GO:0016411 acylglycerol O-acyltransferase activity 6/1556 31/18639 0.193548387096774 2.31847582718302 0.0404552526518324 0.19520530273952 GO:0005201 extracellular matrix structural constituent 21/1556 168/18639 0.125 1.49734897172237 0.0405905763246111 0.19520530273952 GO:0004955 prostaglandin receptor activity 3/1556 10/18639 0.3 3.59363753213368 0.0446388689844199 0.205633008918268 GO:0005031 tumor necrosis factor receptor activity 3/1556 10/18639 0.3 3.59363753213368 0.0446388689844199 0.205633008918268 GO:0005131 growth hormone receptor binding 3/1556 10/18639 0.3 3.59363753213368 0.0446388689844199 0.205633008918268 GO:0030957 Tat protein binding 3/1556 10/18639 0.3 3.59363753213368 0.0446388689844199 0.205633008918268 GO:0050308 sugar-phosphatase activity 3/1556 10/18639 0.3 3.59363753213368 0.0446388689844199 0.205633008918268 GO:1905394 retromer complex binding 3/1556 10/18639 0.3 3.59363753213368 0.0446388689844199 0.205633008918268 GO:0051213 dioxygenase activity 13/1556 93/18639 0.139784946236559 1.67445476407662 0.0449815444173007 0.205633008918268 GO:0004622 lysophospholipase activity 5/1556 24/18639 0.208333333333333 2.49558161953727 0.044998001590714 0.205633008918268 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 5/1556 24/18639 0.208333333333333 2.49558161953727 0.044998001590714 0.205633008918268 GO:0019957 C-C chemokine binding 5/1556 24/18639 0.208333333333333 2.49558161953727 0.044998001590714 0.205633008918268 GO:0035035 histone acetyltransferase binding 5/1556 24/18639 0.208333333333333 2.49558161953727 0.044998001590714 0.205633008918268 GO:0000287 magnesium ion binding 27/1556 230/18639 0.117391304347826 1.40620599083492 0.0450165473907924 0.205633008918268 GO:0141003 histone H2AX kinase activity 39/1556 354/18639 0.110169491525424 1.31969739880615 0.0454130486508546 0.205633008918268 GO:0004601 peroxidase activity 9/1556 57/18639 0.157894736842105 1.8913881748072 0.04542023320369 0.205633008918268 GO:0016504 peptidase activator activity 9/1556 57/18639 0.157894736842105 1.8913881748072 0.04542023320369 0.205633008918268 GO:0019003 GDP binding 11/1556 75/18639 0.146666666666667 1.75688946015424 0.0462240343136839 0.208457804550816 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/1556 17/18639 0.235294117647059 2.81853924088916 0.0478178128551454 0.212340402678596 GO:0008484 sulfuric ester hydrolase activity 4/1556 17/18639 0.235294117647059 2.81853924088916 0.0478178128551454 0.212340402678596 GO:0016805 dipeptidase activity 4/1556 17/18639 0.235294117647059 2.81853924088916 0.0478178128551454 0.212340402678596 GO:0019198 transmembrane receptor protein phosphatase activity 4/1556 17/18639 0.235294117647059 2.81853924088916 0.0478178128551454 0.212340402678596 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 17/1556 132/18639 0.128787878787879 1.54272318298668 0.0481675125097285 0.213076896941891 GO:0008139 nuclear localization sequence binding 5/1556 25/18639 0.2 2.39575835475578 0.0525229342305857 0.230583639292609 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 5/1556 25/18639 0.2 2.39575835475578 0.0525229342305857 0.230583639292609 GO:0019239 deaminase activity 6/1556 33/18639 0.181818181818182 2.17796214068708 0.0528700058329351 0.231231459473101 GO:0032813 tumor necrosis factor receptor superfamily binding 8/1556 50/18639 0.16 1.91660668380463 0.0536989152614905 0.233973845067923 GO:0001786 phosphatidylserine binding 9/1556 59/18639 0.152542372881356 1.8272733214239 0.0547632607497138 0.235332785948943 GO:0004879 nuclear receptor activity 9/1556 59/18639 0.152542372881356 1.8272733214239 0.0547632607497138 0.235332785948943 GO:0035198 miRNA binding 7/1556 42/18639 0.166666666666667 1.99646529562982 0.0571685657980794 0.235332785948943 GO:0048487 beta-tubulin binding 7/1556 42/18639 0.166666666666667 1.99646529562982 0.0571685657980794 0.235332785948943 GO:0004706 JUN kinase kinase kinase activity 4/1556 18/18639 0.222222222222222 2.66195372750643 0.0575545711153974 0.235332785948943 GO:0035615 clathrin adaptor activity 4/1556 18/18639 0.222222222222222 2.66195372750643 0.0575545711153974 0.235332785948943 GO:0098641 cadherin binding involved in cell-cell adhesion 4/1556 18/18639 0.222222222222222 2.66195372750643 0.0575545711153974 0.235332785948943 GO:0000149 SNARE binding 14/1556 106/18639 0.132075471698113 1.58210457389533 0.0575760756139181 0.235332785948943 GO:0004954 prostanoid receptor activity 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0005225 volume-sensitive anion channel activity 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0008199 ferric iron binding 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0008432 JUN kinase binding 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0019203 carbohydrate phosphatase activity 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0034713 type I transforming growth factor beta receptor binding 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0048185 activin binding 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0097493 structural molecule activity conferring elasticity 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0140031 phosphorylation-dependent protein binding 3/1556 11/18639 0.272727272727273 3.26694321103061 0.0576656697234684 0.235332785948943 GO:0019199 transmembrane receptor protein kinase activity 11/1556 78/18639 0.141025641025641 1.68931678860985 0.0586438358599728 0.238484932497223 GO:0016831 carboxy-lyase activity 6/1556 34/18639 0.176470588235294 2.11390443066687 0.0598542796139436 0.240934641627858 GO:0004714 transmembrane receptor protein tyrosine kinase activity 9/1556 60/18639 0.15 1.79681876606684 0.0598698678074402 0.240934641627858 GO:0098531 ligand-modulated transcription factor activity 9/1556 60/18639 0.15 1.79681876606684 0.0598698678074402 0.240934641627858 GO:0008157 protein phosphatase 1 binding 5/1556 26/18639 0.192307692307692 2.30361380264979 0.0607347464887766 0.2427295557948 GO:0043548 phosphatidylinositol 3-kinase binding 5/1556 26/18639 0.192307692307692 2.30361380264979 0.0607347464887766 0.2427295557948 GO:0016651 oxidoreductase activity, acting on NAD(P)H 12/1556 88/18639 0.136363636363636 1.63347160551531 0.0615487601554981 0.245137501787705 GO:0019208 phosphatase regulator activity 15/1556 117/18639 0.128205128205128 1.53574253509986 0.0626770282437617 0.248776286762054 GO:0008375 acetylglucosaminyltransferase activity 7/1556 43/18639 0.162790697674419 1.95003587015006 0.063583230950384 0.250661630879539 GO:0042826 histone deacetylase binding 16/1556 127/18639 0.125984251968504 1.50913912110601 0.0635845724577951 0.250661630879539 GO:0031406 carboxylic acid binding 22/1556 187/18639 0.117647058823529 1.40926962044458 0.0639926500123374 0.251287957662616 GO:0016922 nuclear receptor binding 17/1556 137/18639 0.124087591240876 1.48641941718425 0.0641770797826871 0.251287957662616 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 12/1556 89/18639 0.134831460674157 1.61511799197019 0.0659909536538027 0.256656091559588 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 12/1556 89/18639 0.134831460674157 1.61511799197019 0.0659909536538027 0.256656091559588 GO:0005154 epidermal growth factor receptor binding 6/1556 35/18639 0.171428571428571 2.05350716121924 0.0673605503372261 0.261106614852324 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 4/1556 19/18639 0.210526315789474 2.52185089974293 0.0682648483342947 0.262853685114444 GO:0043395 heparan sulfate proteoglycan binding 4/1556 19/18639 0.210526315789474 2.52185089974293 0.0682648483342947 0.262853685114444 GO:0004364 glutathione transferase activity 5/1556 27/18639 0.185185185185185 2.21829477292202 0.0696309198853775 0.263362491123571 GO:0004683 calcium/calmodulin-dependent protein kinase activity 5/1556 27/18639 0.185185185185185 2.21829477292202 0.0696309198853775 0.263362491123571 GO:0043177 organic acid binding 22/1556 189/18639 0.116402116402116 1.39435671440813 0.0701444789055495 0.263362491123571 GO:0140793 histone H2AXY142 phosphatase activity 12/1556 90/18639 0.133333333333333 1.59717223650386 0.0706377232261734 0.263362491123571 GO:0005246 calcium channel regulator activity 8/1556 53/18639 0.150943396226415 1.80811951302323 0.0713491252215274 0.263362491123571 GO:0004859 phospholipase inhibitor activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0015132 prostaglandin transmembrane transporter activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0015269 calcium-activated potassium channel activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0015368 calcium:monoatomic cation antiporter activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0035251 UDP-glucosyltransferase activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0097677 STAT family protein binding 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 3/1556 12/18639 0.25 2.99469794344473 0.0722599414817046 0.263362491123571 GO:0004222 metalloendopeptidase activity 14/1556 110/18639 0.127272727272727 1.52457349848095 0.0738264664608435 0.268228447110087 GO:0004674 protein serine/threonine kinase activity 45/1556 433/18639 0.103926096997691 1.24490907579689 0.0742416243540134 0.268893883207192 GO:0004033 aldo-keto reductase (NADPH) activity 6/1556 36/18639 0.166666666666667 1.99646529562982 0.0753882467681369 0.2713508633673 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/1556 36/18639 0.166666666666667 1.99646529562982 0.0753882467681369 0.2713508633673 GO:0046915 transition metal ion transmembrane transporter activity 7/1556 45/18639 0.155555555555556 1.8633676092545 0.0776709217042055 0.2779135046758 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 8/1556 54/18639 0.148148148148148 1.77463581833762 0.0779308792231536 0.2779135046758 GO:0051287 NAD binding 8/1556 54/18639 0.148148148148148 1.77463581833762 0.0779308792231536 0.2779135046758 GO:1901681 sulfur compound binding 30/1556 275/18639 0.109090909090909 1.30677728441225 0.0791913588415258 0.280726019054562 GO:0141052 histone H3 demethylase activity 5/1556 28/18639 0.178571428571429 2.13906995960338 0.0792039760404156 0.280726019054562 GO:0016505 peptidase activator activity involved in apoptotic process 4/1556 20/18639 0.2 2.39575835475578 0.0799232036641506 0.282411564166922 GO:0043539 protein serine/threonine kinase activator activity 10/1556 73/18639 0.136986301369863 1.64093037996972 0.0810091326117379 0.28537867689059 GO:0106310 protein serine kinase activity 38/1556 361/18639 0.105263157894737 1.26092544987147 0.0818378780562264 0.287424547476262 GO:0008083 growth factor activity 19/1556 162/18639 0.117283950617284 1.40492002285061 0.0825522163047065 0.289057458299561 GO:0005200 structural constituent of cytoskeleton 14/1556 112/18639 0.125 1.49734897172237 0.0829716944655961 0.289651186402488 GO:0016757 glycosyltransferase activity 29/1556 267/18639 0.108614232209738 1.30106727130932 0.0867436320513761 0.301909518160795 GO:0005172 vascular endothelial growth factor receptor binding 3/1556 13/18639 0.230769230769231 2.76433656317975 0.0883129352649304 0.302824532461699 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/1556 13/18639 0.230769230769231 2.76433656317975 0.0883129352649304 0.302824532461699 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1556 13/18639 0.230769230769231 2.76433656317975 0.0883129352649304 0.302824532461699 GO:0089720 caspase binding 3/1556 13/18639 0.230769230769231 2.76433656317975 0.0883129352649304 0.302824532461699 GO:0140852 histone ubiquitin ligase activity 3/1556 13/18639 0.230769230769231 2.76433656317975 0.0883129352649304 0.302824532461699 GO:0003785 actin monomer binding 5/1556 29/18639 0.172413793103448 2.06530892651361 0.0894417777529749 0.304891236516758 GO:0004629 phospholipase C activity 5/1556 29/18639 0.172413793103448 2.06530892651361 0.0894417777529749 0.304891236516758 GO:0120013 lipid transfer activity 9/1556 65/18639 0.138461538461538 1.65860193790785 0.0898677076412386 0.305444789314356 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1556 21/18639 0.19047619047619 2.28167462357694 0.0924956328661138 0.312543552454303 GO:0140312 cargo adaptor activity 4/1556 21/18639 0.19047619047619 2.28167462357694 0.0924956328661138 0.312543552454303 GO:0044183 protein folding chaperone 10/1556 75/18639 0.133333333333333 1.59717223650386 0.0933002231317843 0.314345809912029 GO:0045296 cadherin binding 35/1556 334/18639 0.104790419161677 1.25526261102474 0.096095442496338 0.322824979284799 GO:0001221 transcription coregulator binding 14/1556 115/18639 0.121739130434783 1.45828769419917 0.0979884998128773 0.32823315399747 GO:0098631 cell adhesion mediator activity 10/1556 76/18639 0.131578947368421 1.57615681233933 0.0998389669150145 0.332228566012041 GO:0008106 alcohol dehydrogenase (NADP+) activity 5/1556 30/18639 0.166666666666667 1.99646529562982 0.100327867216751 0.332228566012041 GO:0032452 histone demethylase activity 5/1556 30/18639 0.166666666666667 1.99646529562982 0.100327867216751 0.332228566012041 GO:0051721 protein phosphatase 2A binding 5/1556 30/18639 0.166666666666667 1.99646529562982 0.100327867216751 0.332228566012041 GO:0005545 1-phosphatidylinositol binding 3/1556 14/18639 0.214285714285714 2.56688395152405 0.105702829729136 0.347833805446547 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/1556 14/18639 0.214285714285714 2.56688395152405 0.105702829729136 0.347833805446547 GO:0031683 G-protein beta/gamma-subunit complex binding 4/1556 22/18639 0.181818181818182 2.17796214068708 0.105940753513918 0.347833805446547 GO:0061980 regulatory RNA binding 8/1556 58/18639 0.137931034482759 1.65224714121089 0.107744896055635 0.3527580071426 GO:1990782 protein tyrosine kinase binding 14/1556 117/18639 0.11965811965812 1.43335969942654 0.10886929003424 0.355387065449862 GO:0019888 protein phosphatase regulator activity 13/1556 107/18639 0.121495327102804 1.45536722485164 0.109161169370277 0.355387065449862 GO:0001222 transcription corepressor binding 7/1556 49/18639 0.142857142857143 1.7112559676827 0.110835454020183 0.358822042484337 GO:0060590 ATPase regulator activity 7/1556 49/18639 0.142857142857143 1.7112559676827 0.110835454020183 0.358822042484337 GO:0016829 lyase activity 22/1556 200/18639 0.11 1.31766709511568 0.111157684051352 0.358862829569686 GO:0140457 protein demethylase activity 5/1556 31/18639 0.161290322580645 1.93206318931918 0.111841831556159 0.360068563259966 GO:0015036 disulfide oxidoreductase activity 6/1556 40/18639 0.15 1.79681876606684 0.112605634162624 0.360524668493042 GO:0032451 demethylase activity 6/1556 40/18639 0.15 1.79681876606684 0.112605634162624 0.360524668493042 GO:0004725 protein tyrosine phosphatase activity 12/1556 98/18639 0.122448979591837 1.46679082944232 0.115307043453513 0.368156648381879 GO:0070888 E-box binding 8/1556 59/18639 0.135593220338983 1.6242429523768 0.116055740809504 0.369529130764329 GO:0042578 phosphoric ester hydrolase activity 37/1556 363/18639 0.101928374655647 1.22097877583972 0.119228613820468 0.37553775529344 GO:0035591 signaling adaptor activity 15/1556 129/18639 0.116279069767442 1.3928827643929 0.119249129939359 0.37553775529344 GO:0005158 insulin receptor binding 4/1556 23/18639 0.173913043478261 2.08326813457025 0.12021096394639 0.37553775529344 GO:0016493 C-C chemokine receptor activity 4/1556 23/18639 0.173913043478261 2.08326813457025 0.12021096394639 0.37553775529344 GO:0016849 phosphorus-oxygen lyase activity 4/1556 23/18639 0.173913043478261 2.08326813457025 0.12021096394639 0.37553775529344 GO:0043274 phospholipase binding 4/1556 23/18639 0.173913043478261 2.08326813457025 0.12021096394639 0.37553775529344 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/1556 23/18639 0.173913043478261 2.08326813457025 0.12021096394639 0.37553775529344 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/1556 41/18639 0.146341463414634 1.75299391811399 0.123137336952407 0.380113337804208 GO:0017080 sodium channel regulator activity 6/1556 41/18639 0.146341463414634 1.75299391811399 0.123137336952407 0.380113337804208 GO:0043425 bHLH transcription factor binding 5/1556 32/18639 0.15625 1.87168621465296 0.123959686843123 0.380113337804208 GO:0004129 cytochrome-c oxidase activity 3/1556 15/18639 0.2 2.39575835475578 0.124299357228468 0.380113337804208 GO:0004953 icosanoid receptor activity 3/1556 15/18639 0.2 2.39575835475578 0.124299357228468 0.380113337804208 GO:0050780 dopamine receptor binding 3/1556 15/18639 0.2 2.39575835475578 0.124299357228468 0.380113337804208 GO:0061578 K63-linked deubiquitinase activity 3/1556 15/18639 0.2 2.39575835475578 0.124299357228468 0.380113337804208 GO:0120283 protein serine/threonine kinase binding 3/1556 15/18639 0.2 2.39575835475578 0.124299357228468 0.380113337804208 GO:0003714 transcription corepressor activity 22/1556 204/18639 0.107843137254902 1.29183048540753 0.129153367681867 0.393917771429695 GO:0005021 vascular endothelial growth factor receptor activity 7/1556 51/18639 0.137254901960784 1.64414789051868 0.12982564945972 0.394928944156995 GO:0019905 syntaxin binding 8/1556 61/18639 0.131147540983607 1.57098908508576 0.133670021351236 0.40520910307922 GO:0051879 Hsp90 protein binding 6/1556 42/18639 0.142857142857143 1.7112559676827 0.134132132144795 0.40520910307922 GO:1902936 phosphatidylinositol bisphosphate binding 13/1556 111/18639 0.117117117117117 1.40292155909122 0.134253921986558 0.40520910307922 GO:0050431 transforming growth factor beta binding 4/1556 24/18639 0.166666666666667 1.99646529562982 0.135253556417525 0.406111067067128 GO:0050699 WW domain binding 4/1556 24/18639 0.166666666666667 1.99646529562982 0.135253556417525 0.406111067067128 GO:0015101 organic cation transmembrane transporter activity 10/1556 81/18639 0.123456790123457 1.47886318194801 0.13639307652922 0.408474355807149 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/1556 52/18639 0.134615384615385 1.61252966185485 0.139891338386617 0.417871291727034 GO:0005516 calmodulin binding 22/1556 207/18639 0.106280193236715 1.2731083044596 0.143725266779147 0.424576231624076 GO:0005521 lamin binding 3/1556 16/18639 0.1875 2.24602345758355 0.1439676091702 0.424576231624076 GO:0015923 mannosidase activity 3/1556 16/18639 0.1875 2.24602345758355 0.1439676091702 0.424576231624076 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/1556 16/18639 0.1875 2.24602345758355 0.1439676091702 0.424576231624076 GO:0140328 floppase activity 3/1556 16/18639 0.1875 2.24602345758355 0.1439676091702 0.424576231624076 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/1556 43/18639 0.13953488372093 1.67145931727148 0.145572494500645 0.428219596767126 GO:0004709 MAP kinase kinase kinase activity 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0015645 fatty acid ligase activity 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0015662 P-type ion transporter activity 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0042974 nuclear retinoic acid receptor binding 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0120515 fatty acid-CoA ligase activity 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0140358 P-type transmembrane transporter activity 4/1556 25/18639 0.16 1.91660668380463 0.151011770167418 0.436465440458947 GO:0008194 UDP-glycosyltransferase activity 16/1556 145/18639 0.110344827586207 1.32179771296871 0.152893793522563 0.440805738041418 GO:0003954 NADH dehydrogenase activity 6/1556 44/18639 0.136363636363636 1.63347160551531 0.157439129542231 0.451663245394668 GO:0043014 alpha-tubulin binding 6/1556 44/18639 0.136363636363636 1.63347160551531 0.157439129542231 0.451663245394668 GO:0050661 NADP binding 7/1556 54/18639 0.12962962962963 1.55280634104542 0.161103283079974 0.458504682036936 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0005092 GDP-dissociation inhibitor activity 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0015278 intracellularly gated calcium channel activity 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0015347 sodium-independent organic anion transmembrane transporter activity 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0038191 neuropilin binding 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0045125 bioactive lipid receptor activity 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0046965 nuclear retinoid X receptor binding 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0051787 misfolded protein binding 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0070403 NAD+ binding 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0070492 oligosaccharide binding 3/1556 17/18639 0.176470588235294 2.11390443066687 0.164571136951998 0.458504682036936 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/1556 26/18639 0.153846153846154 1.84289104211983 0.167425774472626 0.459825764487615 GO:0004435 phosphatidylinositol phospholipase C activity 4/1556 26/18639 0.153846153846154 1.84289104211983 0.167425774472626 0.459825764487615 GO:0005160 transforming growth factor beta receptor binding 4/1556 26/18639 0.153846153846154 1.84289104211983 0.167425774472626 0.459825764487615 GO:0005227 calcium-activated cation channel activity 4/1556 26/18639 0.153846153846154 1.84289104211983 0.167425774472626 0.459825764487615 GO:0030507 spectrin binding 4/1556 26/18639 0.153846153846154 1.84289104211983 0.167425774472626 0.459825764487615 GO:0050681 nuclear androgen receptor binding 4/1556 26/18639 0.153846153846154 1.84289104211983 0.167425774472626 0.459825764487615 GO:0098632 cell-cell adhesion mediator activity 7/1556 55/18639 0.127272727272727 1.52457349848095 0.172221653074519 0.471879186556426 GO:0005484 SNAP receptor activity 5/1556 36/18639 0.138888888888889 1.66372107969152 0.177887509689201 0.486253829551378 GO:0035403 histone H3T6 kinase activity 25/1556 247/18639 0.101214574898785 1.2124283171841 0.182611352867374 0.495504339513308 GO:0015252 proton channel activity 4/1556 27/18639 0.148148148148148 1.77463581833762 0.184433575270408 0.495504339513308 GO:0016405 CoA-ligase activity 4/1556 27/18639 0.148148148148148 1.77463581833762 0.184433575270408 0.495504339513308 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/1556 27/18639 0.148148148148148 1.77463581833762 0.184433575270408 0.495504339513308 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0008525 phosphatidylcholine transporter activity 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0017075 syntaxin-1 binding 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0050811 GABA receptor binding 3/1556 18/18639 0.166666666666667 1.99646529562982 0.185974450119318 0.495504339513308 GO:0004679 AMP-activated protein kinase activity 25/1556 248/18639 0.100806451612903 1.20753949332449 0.187962124446188 0.499651610626448 GO:0001094 TFIID-class transcription factor complex binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0004090 carbonyl reductase (NADPH) activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0005345 purine nucleobase transmembrane transporter activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0005381 iron ion transmembrane transporter activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0005522 profilin binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0008140 cAMP response element binding protein binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0008239 dipeptidyl-peptidase activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0015279 store-operated calcium channel activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0035256 G protein-coupled glutamate receptor binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0043208 glycosphingolipid binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0043422 protein kinase B binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0070513 death domain binding 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 2/1556 10/18639 0.2 2.39575835475578 0.200801205514494 0.512618055487443 GO:0050698 proteoglycan sulfotransferase activity 4/1556 28/18639 0.142857142857143 1.7112559676827 0.20197184180874 0.514473328915011 GO:0005262 calcium channel activity 14/1556 131/18639 0.106870229007634 1.28017622009851 0.20369065491744 0.51771374791516 GO:1990841 promoter-specific chromatin binding 8/1556 68/18639 0.117647058823529 1.40926962044458 0.204825849207389 0.519459867027054 GO:0000146 microfilament motor activity 5/1556 38/18639 0.131578947368421 1.57615681233933 0.20765503338569 0.520786513015544 GO:0042887 amide transmembrane transporter activity 5/1556 38/18639 0.131578947368421 1.57615681233933 0.20765503338569 0.520786513015544 GO:0030506 ankyrin binding 3/1556 19/18639 0.157894736842105 1.8913881748072 0.208045000454009 0.520786513015544 GO:0034987 immunoglobulin receptor binding 3/1556 19/18639 0.157894736842105 1.8913881748072 0.208045000454009 0.520786513015544 GO:0042834 peptidoglycan binding 3/1556 19/18639 0.157894736842105 1.8913881748072 0.208045000454009 0.520786513015544 GO:0046527 glucosyltransferase activity 3/1556 19/18639 0.157894736842105 1.8913881748072 0.208045000454009 0.520786513015544 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/1556 48/18639 0.125 1.49734897172237 0.208731145773556 0.521378012826621 GO:0043130 ubiquitin binding 11/1556 100/18639 0.11 1.31766709511568 0.211658035317861 0.527551963297635 GO:0017171 serine hydrolase activity 20/1556 198/18639 0.101010101010101 1.20997896704838 0.217034333648982 0.533810997921851 GO:0004518 nuclease activity 21/1556 209/18639 0.100478468899522 1.20361065669549 0.217074274217344 0.533810997921851 GO:0015459 potassium channel regulator activity 7/1556 59/18639 0.11864406779661 1.4212125833297 0.219738863457203 0.533810997921851 GO:0070063 RNA polymerase binding 7/1556 59/18639 0.11864406779661 1.4212125833297 0.219738863457203 0.533810997921851 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 4/1556 29/18639 0.137931034482759 1.65224714121089 0.219976652057663 0.533810997921851 GO:0097472 cyclin-dependent protein kinase activity 4/1556 29/18639 0.137931034482759 1.65224714121089 0.219976652057663 0.533810997921851 GO:0099604 ligand-gated calcium channel activity 4/1556 29/18639 0.137931034482759 1.65224714121089 0.219976652057663 0.533810997921851 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 24/1556 243/18639 0.0987654320987654 1.18309054555841 0.2223059497668 0.533810997921851 GO:0048306 calcium-dependent protein binding 9/1556 80/18639 0.1125 1.34761407455013 0.222341733790433 0.533810997921851 GO:0043022 ribosome binding 12/1556 112/18639 0.107142857142857 1.28344197576203 0.223951199941402 0.533810997921851 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/1556 70/18639 0.114285714285714 1.36900477414616 0.227501262350121 0.533810997921851 GO:0097110 scaffold protein binding 8/1556 70/18639 0.114285714285714 1.36900477414616 0.227501262350121 0.533810997921851 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 3/1556 20/18639 0.15 1.79681876606684 0.230654729299279 0.533810997921851 GO:0030742 GTP-dependent protein binding 3/1556 20/18639 0.15 1.79681876606684 0.230654729299279 0.533810997921851 GO:0043024 ribosomal small subunit binding 3/1556 20/18639 0.15 1.79681876606684 0.230654729299279 0.533810997921851 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/1556 60/18639 0.116666666666667 1.39752570694087 0.232291202991183 0.533810997921851 GO:0003953 NAD+ nucleosidase activity 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0005114 type II transforming growth factor beta receptor binding 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0005536 D-glucose binding 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0008526 phosphatidylinositol transfer activity 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0015205 nucleobase transmembrane transporter activity 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0032794 GTPase activating protein binding 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0048407 platelet-derived growth factor binding 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0050998 nitric-oxide synthase binding 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0140537 transcription regulator activator activity 2/1556 11/18639 0.181818181818182 2.17796214068708 0.232609102356945 0.533810997921851 GO:0030971 receptor tyrosine kinase binding 9/1556 81/18639 0.111111111111111 1.33097686375321 0.233085315948084 0.533810997921851 GO:0004676 3-phosphoinositide-dependent protein kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0004711 ribosomal protein S6 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0035175 histone H3S10 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0035979 histone H2AXS139 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0044022 histone H3S28 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0044023 histone H4S1 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0044024 histone H2AS1 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0044025 histone H2BS14 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0072354 histone H3T3 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0072371 histone H2AS121 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0072518 Rho-dependent protein serine/threonine kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0140823 histone H2BS36 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0140855 histone H3S57 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0140995 histone H2A kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0140997 histone H4 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0140998 histone H2B kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:1990244 histone H2AT120 kinase activity 24/1556 245/18639 0.0979591836734694 1.17343266355385 0.234434683297862 0.533810997921851 GO:0022839 monoatomic ion-gated channel activity 4/1556 30/18639 0.133333333333333 1.59717223650386 0.238384157417803 0.539623512592253 GO:0031210 phosphatidylcholine binding 4/1556 30/18639 0.133333333333333 1.59717223650386 0.238384157417803 0.539623512592253 GO:0070566 adenylyltransferase activity 4/1556 30/18639 0.133333333333333 1.59717223650386 0.238384157417803 0.539623512592253 GO:0015144 carbohydrate transmembrane transporter activity 5/1556 40/18639 0.125 1.49734897172237 0.238897794180145 0.539732053518105 GO:0004677 DNA-dependent protein kinase activity 24/1556 246/18639 0.0975609756097561 1.16866261207599 0.240606881893738 0.54148228371814 GO:0140857 histone H3T45 kinase activity 24/1556 246/18639 0.0975609756097561 1.16866261207599 0.240606881893738 0.54148228371814 GO:0140789 histone phosphatase activity 14/1556 136/18639 0.102941176470588 1.23311091788901 0.244555495312506 0.549301974936423 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/1556 61/18639 0.114754098360656 1.37461544945004 0.245075430240805 0.549405074756467 GO:0035402 histone H3T11 kinase activity 24/1556 247/18639 0.097165991902834 1.16393118449674 0.246848553179087 0.552311724197995 GO:0005010 insulin-like growth factor receptor activity 6/1556 51/18639 0.117647058823529 1.40926962044458 0.250535988668213 0.559482101862156 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1556 21/18639 0.142857142857143 1.7112559676827 0.253681245371473 0.562173161349019 GO:0019200 carbohydrate kinase activity 3/1556 21/18639 0.142857142857143 1.7112559676827 0.253681245371473 0.562173161349019 GO:0051010 microtubule plus-end binding 3/1556 21/18639 0.142857142857143 1.7112559676827 0.253681245371473 0.562173161349019 GO:0072542 protein phosphatase activator activity 3/1556 21/18639 0.142857142857143 1.7112559676827 0.253681245371473 0.562173161349019 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/1556 41/18639 0.121951219512195 1.46082826509499 0.254975635461775 0.562889069524186 GO:0140828 metal cation:monoatomic cation antiporter activity 5/1556 41/18639 0.121951219512195 1.46082826509499 0.254975635461775 0.562889069524186 GO:0016878 acid-thiol ligase activity 4/1556 31/18639 0.129032258064516 1.54565055145534 0.257131168656565 0.566568487591177 GO:0005025 transforming growth factor beta receptor activity, type I 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0005026 transforming growth factor beta receptor activity, type II 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0005095 GTPase inhibitor activity 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0016208 AMP binding 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0016361 activin receptor activity, type I 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0016362 activin receptor activity, type II 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0016801 hydrolase activity, acting on ether bonds 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0016803 ether hydrolase activity 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0016840 carbon-nitrogen lyase activity 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0017002 activin receptor activity 2/1556 12/18639 0.166666666666667 1.99646529562982 0.264678934531993 0.571253044921005 GO:0008236 serine-type peptidase activity 19/1556 194/18639 0.0979381443298969 1.17318063763814 0.266322730052696 0.57277105995862 GO:0051117 ATPase binding 9/1556 84/18639 0.107142857142857 1.28344197576203 0.266370665502758 0.57277105995862 GO:0004867 serine-type endopeptidase inhibitor activity 10/1556 95/18639 0.105263157894737 1.26092544987147 0.268505911495386 0.576293243376208 GO:0008970 phospholipase A1 activity 3/1556 22/18639 0.136363636363636 1.63347160551531 0.277008691454244 0.592348843903079 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/1556 22/18639 0.136363636363636 1.63347160551531 0.277008691454244 0.592348843903079 GO:0005003 ephrin receptor activity 6/1556 53/18639 0.113207547169811 1.35608963476742 0.279603587796027 0.592432464818274 GO:0005005 transmembrane-ephrin receptor activity 6/1556 53/18639 0.113207547169811 1.35608963476742 0.279603587796027 0.592432464818274 GO:0005544 calcium-dependent phospholipid binding 6/1556 53/18639 0.113207547169811 1.35608963476742 0.279603587796027 0.592432464818274 GO:0038064 collagen receptor activity 6/1556 53/18639 0.113207547169811 1.35608963476742 0.279603587796027 0.592432464818274 GO:0140296 general transcription initiation factor binding 6/1556 53/18639 0.113207547169811 1.35608963476742 0.279603587796027 0.592432464818274 GO:0046906 tetrapyrrole binding 15/1556 152/18639 0.0986842105263158 1.1821176092545 0.287106819358831 0.607220444592857 GO:0048156 tau protein binding 5/1556 43/18639 0.116279069767442 1.3928827643929 0.287849699680097 0.607465450786413 GO:0016758 hexosyltransferase activity 19/1556 197/18639 0.0964467005076142 1.15531494264873 0.288744831666902 0.607465450786413 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 13/1556 130/18639 0.1 1.19787917737789 0.289217516005166 0.607465450786413 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 9/1556 86/18639 0.104651162790698 1.25359448795361 0.289319179321915 0.607465450786413 GO:0003925 G protein activity 6/1556 54/18639 0.111111111111111 1.33097686375321 0.294416125885534 0.609801438209126 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 4/1556 33/18639 0.121212121212121 1.45197476045805 0.295397237550994 0.609801438209126 GO:0004535 poly(A)-specific ribonuclease activity 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0005542 folic acid binding 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0019855 calcium channel inhibitor activity 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0030955 potassium ion binding 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0035673 oligopeptide transmembrane transporter activity 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0046974 histone H3K9 methyltransferase activity 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0046975 histone H3K36 methyltransferase activity 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0070123 transforming growth factor beta receptor activity, type III 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1556 13/18639 0.153846153846154 1.84289104211983 0.296745479853276 0.609801438209126 GO:0020037 heme binding 14/1556 142/18639 0.0985915492957746 1.18100763966834 0.297289658816474 0.609838432864236 GO:0017022 myosin binding 8/1556 76/18639 0.105263157894737 1.26092544987147 0.300125560644507 0.613225982962517 GO:0004022 alcohol dehydrogenase (NAD+) activity 3/1556 23/18639 0.130434782608696 1.56245110092769 0.300528350580423 0.613225982962517 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/1556 23/18639 0.130434782608696 1.56245110092769 0.300528350580423 0.613225982962517 GO:0001046 core promoter sequence-specific DNA binding 5/1556 44/18639 0.113636363636364 1.36122633792942 0.304569003543926 0.616047949576631 GO:0001223 transcription coactivator binding 5/1556 44/18639 0.113636363636364 1.36122633792942 0.304569003543926 0.616047949576631 GO:0016790 thiolester hydrolase activity 5/1556 44/18639 0.113636363636364 1.36122633792942 0.304569003543926 0.616047949576631 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1556 44/18639 0.113636363636364 1.36122633792942 0.304569003543926 0.616047949576631 GO:0030547 signaling receptor inhibitor activity 5/1556 44/18639 0.113636363636364 1.36122633792942 0.304569003543926 0.616047949576631 GO:0043021 ribonucleoprotein complex binding 17/1556 177/18639 0.096045197740113 1.15050542460024 0.308731066152046 0.623378581307006 GO:0004540 RNA nuclease activity 12/1556 121/18639 0.0991735537190083 1.18797934946568 0.309734870514906 0.624317765090045 GO:0030332 cyclin binding 4/1556 34/18639 0.117647058823529 1.40926962044458 0.314797449109447 0.631228795013579 GO:0051427 hormone receptor binding 4/1556 34/18639 0.117647058823529 1.40926962044458 0.314797449109447 0.631228795013579 GO:0090482 vitamin transmembrane transporter activity 4/1556 34/18639 0.117647058823529 1.40926962044458 0.314797449109447 0.631228795013579 GO:0008514 organic anion transmembrane transporter activity 25/1556 269/18639 0.0929368029739777 1.113270610946 0.31654976121667 0.633646240501071 GO:0140303 intramembrane lipid transporter activity 5/1556 45/18639 0.111111111111111 1.33097686375321 0.321426233797252 0.636841276029421 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1556 24/18639 0.125 1.49734897172237 0.324139035460836 0.636841276029421 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1556 24/18639 0.125 1.49734897172237 0.324139035460836 0.636841276029421 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1556 24/18639 0.125 1.49734897172237 0.324139035460836 0.636841276029421 GO:0005540 hyaluronic acid binding 3/1556 24/18639 0.125 1.49734897172237 0.324139035460836 0.636841276029421 GO:0030215 semaphorin receptor binding 3/1556 24/18639 0.125 1.49734897172237 0.324139035460836 0.636841276029421 GO:0030170 pyridoxal phosphate binding 6/1556 56/18639 0.107142857142857 1.28344197576203 0.324464810276555 0.636841276029421 GO:0016500 protein-hormone receptor activity 7/1556 67/18639 0.104477611940299 1.25151555845451 0.325546175337917 0.636841276029421 GO:0004065 arylsulfatase activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0008494 translation activator activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0016530 metallochaperone activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0019992 diacylglycerol binding 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0032036 myosin heavy chain binding 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0032454 histone H3K9 demethylase activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0061665 SUMO ligase activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0071933 Arp2/3 complex binding 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0098599 palmitoyl hydrolase activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0098821 BMP receptor activity 2/1556 14/18639 0.142857142857143 1.7112559676827 0.328585921540633 0.636841276029421 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1556 46/18639 0.108695652173913 1.3020425841064 0.338384759474739 0.65473779003543 GO:0005548 phospholipid transporter activity 7/1556 68/18639 0.102941176470588 1.23311091788901 0.33939932751683 0.654995534534644 GO:0070279 vitamin B6 binding 6/1556 57/18639 0.105263157894737 1.26092544987147 0.339648245259121 0.654995534534644 GO:0003707 nuclear steroid receptor activity 3/1556 25/18639 0.12 1.43745501285347 0.347747298909939 0.665081055175939 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1556 25/18639 0.12 1.43745501285347 0.347747298909939 0.665081055175939 GO:0017025 TBP-class protein binding 3/1556 25/18639 0.12 1.43745501285347 0.347747298909939 0.665081055175939 GO:0019211 phosphatase activator activity 3/1556 25/18639 0.12 1.43745501285347 0.347747298909939 0.665081055175939 GO:0047617 fatty acyl-CoA hydrolase activity 3/1556 25/18639 0.12 1.43745501285347 0.347747298909939 0.665081055175939 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/1556 58/18639 0.103448275862069 1.23918535590816 0.354903334016971 0.672995078899296 GO:0043495 protein-membrane adaptor activity 5/1556 47/18639 0.106382978723404 1.27433955040201 0.355408999205775 0.672995078899296 GO:0140359 ABC-type transporter activity 5/1556 47/18639 0.106382978723404 1.27433955040201 0.355408999205775 0.672995078899296 GO:0004559 alpha-mannosidase activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0005523 tropomyosin binding 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0016846 carbon-sulfur lyase activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0031386 protein tag activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0047372 monoacylglycerol lipase activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0051371 muscle alpha-actinin binding 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0140776 protein-containing complex destabilizing activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0141047 molecular tag activity 2/1556 15/18639 0.133333333333333 1.59717223650386 0.360014623742505 0.672995078899296 GO:0052689 carboxylic ester hydrolase activity 9/1556 92/18639 0.0978260869565217 1.17183832569576 0.360703704141525 0.6731974123994 GO:0031593 polyubiquitin modification-dependent protein binding 6/1556 59/18639 0.101694915254237 1.2181822142826 0.370204972193548 0.685189538044224 GO:0004519 endonuclease activity 12/1556 127/18639 0.094488188976378 1.1318543408295 0.37096249724865 0.685189538044224 GO:0004529 DNA exonuclease activity 3/1556 26/18639 0.115384615384615 1.38216828158988 0.371267497749588 0.685189538044224 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1556 26/18639 0.115384615384615 1.38216828158988 0.371267497749588 0.685189538044224 GO:0015145 monosaccharide transmembrane transporter activity 3/1556 26/18639 0.115384615384615 1.38216828158988 0.371267497749588 0.685189538044224 GO:0016289 acyl-CoA hydrolase activity 3/1556 26/18639 0.115384615384615 1.38216828158988 0.371267497749588 0.685189538044224 GO:0051139 metal cation:proton antiporter activity 3/1556 26/18639 0.115384615384615 1.38216828158988 0.371267497749588 0.685189538044224 GO:0030551 cyclic nucleotide binding 4/1556 37/18639 0.108108108108108 1.29500451608421 0.373401306263053 0.688031977677072 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1556 60/18639 0.1 1.19787917737789 0.385528724327144 0.694828468955355 GO:0005004 GPI-linked ephrin receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0005008 hepatocyte growth factor receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0005009 insulin receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0005020 stem cell factor receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0008288 boss receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0035254 glutamate receptor binding 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0036332 placental growth factor receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1556 49/18639 0.102040816326531 1.22232569120193 0.38951837649236 0.694828468955355 GO:0004721 phosphoprotein phosphatase activity 16/1556 175/18639 0.0914285714285714 1.09520381931693 0.389862764494055 0.694828468955355 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0004708 MAP kinase kinase activity 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0005024 transforming growth factor beta receptor activity 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0008142 oxysterol binding 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0016722 oxidoreductase activity, acting on metal ions 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0043023 ribosomal large subunit binding 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0070411 I-SMAD binding 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0140327 flippase activity 2/1556 16/18639 0.125 1.49734897172237 0.39087848296712 0.694828468955355 GO:0001671 ATPase activator activity 3/1556 27/18639 0.111111111111111 1.33097686375321 0.394621738059485 0.699337300322543 GO:0035255 ionotropic glutamate receptor binding 3/1556 27/18639 0.111111111111111 1.33097686375321 0.394621738059485 0.699337300322543 GO:0003774 cytoskeletal motor activity 14/1556 153/18639 0.0915032679738562 1.09609859367912 0.400638922751688 0.708916811403368 GO:0046943 carboxylic acid transmembrane transporter activity 17/1556 188/18639 0.0904255319148936 1.08318861784171 0.402131343579645 0.710472907330501 GO:0004527 exonuclease activity 8/1556 84/18639 0.0952380952380952 1.14083731178847 0.403095640193271 0.711092613369865 GO:0005006 epidermal growth factor receptor activity 5/1556 50/18639 0.1 1.19787917737789 0.406538776959207 0.712826690613798 GO:0005007 fibroblast growth factor receptor activity 5/1556 50/18639 0.1 1.19787917737789 0.406538776959207 0.712826690613798 GO:0005017 platelet-derived growth factor receptor activity 5/1556 50/18639 0.1 1.19787917737789 0.406538776959207 0.712826690613798 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1556 50/18639 0.1 1.19787917737789 0.406538776959207 0.712826690613798 GO:0004521 RNA endonuclease activity 7/1556 73/18639 0.0958904109589041 1.1486512659788 0.409384874153968 0.716732732846599 GO:0005342 organic acid transmembrane transporter activity 17/1556 189/18639 0.0899470899470899 1.07745746113355 0.41080516239435 0.71813451465317 GO:0015179 L-amino acid transmembrane transporter activity 6/1556 62/18639 0.0967741935483871 1.15923791359151 0.416148631498717 0.723707536594167 GO:0046875 ephrin receptor binding 3/1556 28/18639 0.107142857142857 1.28344197576203 0.417739725609575 0.723707536594167 GO:0046966 nuclear thyroid hormone receptor binding 3/1556 28/18639 0.107142857142857 1.28344197576203 0.417739725609575 0.723707536594167 GO:0051119 sugar transmembrane transporter activity 3/1556 28/18639 0.107142857142857 1.28344197576203 0.417739725609575 0.723707536594167 GO:0051959 dynein light intermediate chain binding 3/1556 28/18639 0.107142857142857 1.28344197576203 0.417739725609575 0.723707536594167 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1556 28/18639 0.107142857142857 1.28344197576203 0.417739725609575 0.723707536594167 GO:0032182 ubiquitin-like protein binding 11/1556 120/18639 0.0916666666666667 1.0980559125964 0.41916669246507 0.724035890647521 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1556 17/18639 0.117647058823529 1.40926962044458 0.421052795769136 0.724035890647521 GO:0031489 myosin V binding 2/1556 17/18639 0.117647058823529 1.40926962044458 0.421052795769136 0.724035890647521 GO:0045236 CXCR chemokine receptor binding 2/1556 17/18639 0.117647058823529 1.40926962044458 0.421052795769136 0.724035890647521 GO:0048038 quinone binding 2/1556 17/18639 0.117647058823529 1.40926962044458 0.421052795769136 0.724035890647521 GO:0005179 hormone activity 12/1556 132/18639 0.0909090909090909 1.08898107034354 0.423057402959834 0.725009457098113 GO:0005030 neurotrophin receptor activity 5/1556 51/18639 0.0980392156862745 1.17439135037048 0.423495601773445 0.725009457098113 GO:0005048 signal sequence binding 5/1556 51/18639 0.0980392156862745 1.17439135037048 0.423495601773445 0.725009457098113 GO:1901682 sulfur compound transmembrane transporter activity 6/1556 63/18639 0.0952380952380952 1.14083731178847 0.431399914149281 0.732346991808049 GO:0004532 RNA exonuclease activity 4/1556 40/18639 0.1 1.19787917737789 0.431572903714321 0.732346991808049 GO:0030331 nuclear estrogen receptor binding 4/1556 40/18639 0.1 1.19787917737789 0.431572903714321 0.732346991808049 GO:0050997 quaternary ammonium group binding 4/1556 40/18639 0.1 1.19787917737789 0.431572903714321 0.732346991808049 GO:0071855 neuropeptide receptor binding 4/1556 40/18639 0.1 1.19787917737789 0.431572903714321 0.732346991808049 GO:0140662 ATP-dependent protein folding chaperone 4/1556 40/18639 0.1 1.19787917737789 0.431572903714321 0.732346991808049 GO:0030159 signaling receptor complex adaptor activity 5/1556 52/18639 0.0961538461538462 1.1518069013249 0.440360250943544 0.744325582992763 GO:0004181 metallocarboxypeptidase activity 3/1556 29/18639 0.103448275862069 1.23918535590816 0.440558541788642 0.744325582992763 GO:0106222 lncRNA binding 3/1556 29/18639 0.103448275862069 1.23918535590816 0.440558541788642 0.744325582992763 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 16/1556 181/18639 0.0883977900552486 1.05889872033405 0.443631520581221 0.748309678835284 GO:0004536 DNA nuclease activity 6/1556 64/18639 0.09375 1.12301172879177 0.446583674915616 0.748309678835284 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1556 18/18639 0.111111111111111 1.33097686375321 0.450437588975363 0.748309678835284 GO:0008409 5'-3' exonuclease activity 2/1556 18/18639 0.111111111111111 1.33097686375321 0.450437588975363 0.748309678835284 GO:0015172 acidic amino acid transmembrane transporter activity 2/1556 18/18639 0.111111111111111 1.33097686375321 0.450437588975363 0.748309678835284 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1556 18/18639 0.111111111111111 1.33097686375321 0.450437588975363 0.748309678835284 GO:1901611 phosphatidylglycerol binding 2/1556 18/18639 0.111111111111111 1.33097686375321 0.450437588975363 0.748309678835284 GO:1990381 ubiquitin-specific protease binding 2/1556 18/18639 0.111111111111111 1.33097686375321 0.450437588975363 0.748309678835284 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 20/1556 229/18639 0.0873362445414847 1.04618268766628 0.450500449417567 0.748309678835284 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1556 41/18639 0.0975609756097561 1.16866261207599 0.450664500282164 0.748309678835284 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/1556 41/18639 0.0975609756097561 1.16866261207599 0.450664500282164 0.748309678835284 GO:0140318 protein transporter activity 4/1556 41/18639 0.0975609756097561 1.16866261207599 0.450664500282164 0.748309678835284 GO:0004864 protein phosphatase inhibitor activity 5/1556 53/18639 0.0943396226415094 1.13007469563952 0.457105736688077 0.755756845679717 GO:0008146 sulfotransferase activity 5/1556 53/18639 0.0943396226415094 1.13007469563952 0.457105736688077 0.755756845679717 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1556 53/18639 0.0943396226415094 1.13007469563952 0.457105736688077 0.755756845679717 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/1556 30/18639 0.1 1.19787917737789 0.463022362274291 0.762276871982817 GO:0016769 transferase activity, transferring nitrogenous groups 3/1556 30/18639 0.1 1.19787917737789 0.463022362274291 0.762276871982817 GO:0048019 receptor antagonist activity 3/1556 30/18639 0.1 1.19787917737789 0.463022362274291 0.762276871982817 GO:0005229 intracellularly calcium-gated chloride channel activity 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0005520 insulin-like growth factor binding 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0008301 DNA binding, bending 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0031420 alkali metal ion binding 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0046624 sphingolipid transporter activity 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0070003 threonine-type peptidase activity 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0141147 intracellularly calcium-gated channel activity 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:1990380 K48-linked deubiquitinase activity 2/1556 19/18639 0.105263157894737 1.26092544987147 0.478954364095523 0.778552746124419 GO:0003712 transcription coregulator activity 42/1556 495/18639 0.0848484848484849 1.01638233232064 0.479731814914286 0.778724332612966 GO:0008327 methyl-CpG binding 3/1556 31/18639 0.0967741935483871 1.15923791359151 0.485082133019046 0.784114633429672 GO:0047499 calcium-independent phospholipase A2 activity 3/1556 31/18639 0.0967741935483871 1.15923791359151 0.485082133019046 0.784114633429672 GO:0070325 lipoprotein particle receptor binding 3/1556 31/18639 0.0967741935483871 1.15923791359151 0.485082133019046 0.784114633429672 GO:0031490 chromatin DNA binding 11/1556 128/18639 0.0859375 1.02942741805913 0.506008039545962 0.808897734327209 GO:0004252 serine-type endopeptidase activity 15/1556 176/18639 0.0852272727272727 1.02091975344707 0.506033147806691 0.808897734327209 GO:0019212 phosphatase inhibitor activity 5/1556 56/18639 0.0892857142857143 1.06953497980169 0.506382136054134 0.808897734327209 GO:0001972 retinoic acid binding 2/1556 20/18639 0.1 1.19787917737789 0.506543212406217 0.808897734327209 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/1556 20/18639 0.1 1.19787917737789 0.506543212406217 0.808897734327209 GO:0061608 nuclear import signal receptor activity 2/1556 20/18639 0.1 1.19787917737789 0.506543212406217 0.808897734327209 GO:0022884 macromolecule transmembrane transporter activity 3/1556 32/18639 0.09375 1.12301172879177 0.506695215808071 0.808897734327209 GO:0051059 NF-kappaB binding 3/1556 32/18639 0.09375 1.12301172879177 0.506695215808071 0.808897734327209 GO:0140142 nucleocytoplasmic carrier activity 3/1556 32/18639 0.09375 1.12301172879177 0.506695215808071 0.808897734327209 GO:0002039 p53 binding 6/1556 69/18639 0.0869565217391304 1.04163406728512 0.520821259724246 0.830305144457223 GO:0005506 iron ion binding 13/1556 154/18639 0.0844155844155844 1.01119670817614 0.525521519982467 0.836647584697362 GO:0008013 beta-catenin binding 9/1556 106/18639 0.0849056603773585 1.01706722607557 0.529566584069727 0.841930961504545 GO:0042562 hormone binding 8/1556 94/18639 0.0851063829787234 1.01947164032161 0.531069780136977 0.843018749191056 GO:0005123 death receptor binding 2/1556 21/18639 0.0952380952380952 1.14083731178847 0.533160261567769 0.843018749191056 GO:0015125 bile acid transmembrane transporter activity 2/1556 21/18639 0.0952380952380952 1.14083731178847 0.533160261567769 0.843018749191056 GO:0035613 RNA stem-loop binding 2/1556 21/18639 0.0952380952380952 1.14083731178847 0.533160261567769 0.843018749191056 GO:0030165 PDZ domain binding 7/1556 83/18639 0.0843373493975904 1.01025954718617 0.546062324970644 0.862242826486344 GO:0008376 acetylgalactosaminyltransferase activity 3/1556 34/18639 0.0882352941176471 1.05695221533343 0.548440584394197 0.863644887653362 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1556 34/18639 0.0882352941176471 1.05695221533343 0.548440584394197 0.863644887653362 GO:0015377 chloride:monoatomic cation symporter activity 2/1556 22/18639 0.0909090909090909 1.08898107034354 0.558775418579121 0.871775956396687 GO:0070034 telomerase RNA binding 2/1556 22/18639 0.0909090909090909 1.08898107034354 0.558775418579121 0.871775956396687 GO:0140517 protein-RNA adaptor activity 2/1556 22/18639 0.0909090909090909 1.08898107034354 0.558775418579121 0.871775956396687 GO:0000175 3'-5'-RNA exonuclease activity 3/1556 35/18639 0.0857142857142857 1.02675358060962 0.56851624992199 0.871775956396687 GO:0004623 phospholipase A2 activity 3/1556 35/18639 0.0857142857142857 1.02675358060962 0.56851624992199 0.871775956396687 GO:0043015 gamma-tubulin binding 3/1556 35/18639 0.0857142857142857 1.02675358060962 0.56851624992199 0.871775956396687 GO:0061631 ubiquitin conjugating enzyme activity 3/1556 35/18639 0.0857142857142857 1.02675358060962 0.56851624992199 0.871775956396687 GO:0001098 basal transcription machinery binding 5/1556 60/18639 0.0833333333333333 0.99823264781491 0.569068850990066 0.871775956396687 GO:0001099 basal RNA polymerase II transcription machinery binding 5/1556 60/18639 0.0833333333333333 0.99823264781491 0.569068850990066 0.871775956396687 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0003796 lysozyme activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0004382 GDP phosphatase activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0005528 FK506 binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0008190 eukaryotic initiation factor 4E binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0015203 polyamine transmembrane transporter activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0031419 cobalamin binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0031434 mitogen-activated protein kinase kinase binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0032052 bile acid binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0043121 neurotrophin binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0043295 glutathione binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0070097 delta-catenin binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0097177 mitochondrial ribosome binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0099122 RNA polymerase II C-terminal domain binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0141109 transporter activator activity 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:1990763 arrestin family protein binding 1/1556 10/18639 0.1 1.19787917737789 0.58186185521096 0.871775956396687 GO:0005212 structural constituent of eye lens 2/1556 23/18639 0.0869565217391304 1.04163406728512 0.58337037743614 0.871775956396687 GO:0140103 catalytic activity, acting on a glycoprotein 2/1556 23/18639 0.0869565217391304 1.04163406728512 0.58337037743614 0.871775956396687 GO:0004190 aspartic-type endopeptidase activity 3/1556 36/18639 0.0833333333333333 0.99823264781491 0.588031206060461 0.871775956396687 GO:0016409 palmitoyltransferase activity 3/1556 36/18639 0.0833333333333333 0.99823264781491 0.588031206060461 0.871775956396687 GO:0099094 ligand-gated monoatomic cation channel activity 11/1556 136/18639 0.0808823529411765 0.968872864055648 0.588957434546339 0.871775956396687 GO:0016791 phosphatase activity 22/1556 273/18639 0.0805860805860806 0.965323879205627 0.601267462280079 0.871775956396687 GO:0019842 vitamin binding 12/1556 150/18639 0.08 0.958303341902314 0.604551689930242 0.871775956396687 GO:0004806 triacylglycerol lipase activity 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0005315 phosphate transmembrane transporter activity 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0015149 hexose transmembrane transporter activity 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0015295 solute:proton symporter activity 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0030552 cAMP binding 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0055056 D-glucose transmembrane transporter activity 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0070300 phosphatidic acid binding 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/1556 24/18639 0.0833333333333333 0.99823264781491 0.606936863070258 0.871775956396687 GO:0070001 aspartic-type peptidase activity 3/1556 37/18639 0.0810810810810811 0.971253387063156 0.606969138395526 0.871775956396687 GO:0015291 secondary active transmembrane transporter activity 23/1556 287/18639 0.0801393728222996 0.959972859919565 0.613029551426289 0.871775956396687 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0002162 dystroglycan binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0004016 adenylate cyclase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0008046 axon guidance receptor activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0008503 benzodiazepine receptor activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0010854 adenylate cyclase regulator activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0015217 ADP transmembrane transporter activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0019107 myristoyltransferase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0019206 nucleoside kinase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0019215 intermediate filament binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0031731 CCR6 chemokine receptor binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0032050 clathrin heavy chain binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0032404 mismatch repair complex binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0034056 estrogen response element binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0035252 UDP-xylosyltransferase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0042285 xylosyltransferase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0045294 alpha-catenin binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0070697 activin receptor binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0070990 snRNP binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:1900750 oligopeptide binding 1/1556 11/18639 0.0909090909090909 1.08898107034354 0.616787130496362 0.871775956396687 GO:0003727 single-stranded RNA binding 7/1556 89/18639 0.0786516853932584 0.942152161982612 0.621337992822341 0.876876952789899 GO:0005501 retinoid binding 3/1556 38/18639 0.0789473684210526 0.945694087403599 0.625317847305597 0.876876952789899 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/1556 38/18639 0.0789473684210526 0.945694087403599 0.625317847305597 0.876876952789899 GO:0019840 isoprenoid binding 3/1556 38/18639 0.0789473684210526 0.945694087403599 0.625317847305597 0.876876952789899 GO:0042162 telomeric DNA binding 3/1556 38/18639 0.0789473684210526 0.945694087403599 0.625317847305597 0.876876952789899 GO:0015171 amino acid transmembrane transporter activity 8/1556 102/18639 0.0784313725490196 0.939513080296386 0.625457103355173 0.876876952789899 GO:0000030 mannosyltransferase activity 2/1556 25/18639 0.08 0.958303341902314 0.629475086040721 0.876876952789899 GO:0005251 delayed rectifier potassium channel activity 2/1556 25/18639 0.08 0.958303341902314 0.629475086040721 0.876876952789899 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1556 25/18639 0.08 0.958303341902314 0.629475086040721 0.876876952789899 GO:0017056 structural constituent of nuclear pore 2/1556 25/18639 0.08 0.958303341902314 0.629475086040721 0.876876952789899 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1556 25/18639 0.08 0.958303341902314 0.629475086040721 0.876876952789899 GO:0019707 protein-cysteine S-acyltransferase activity 2/1556 25/18639 0.08 0.958303341902314 0.629475086040721 0.876876952789899 GO:0046873 metal ion transmembrane transporter activity 36/1556 450/18639 0.08 0.958303341902314 0.631681569641071 0.87889428477071 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 10/1556 128/18639 0.078125 0.935843107326478 0.633545784144705 0.88043113168311 GO:0005253 monoatomic anion channel activity 8/1556 103/18639 0.0776699029126214 0.930391594079916 0.636513375423258 0.880510168812095 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1556 39/18639 0.0769230769230769 0.921445521059917 0.643068885184321 0.880510168812095 GO:0004000 adenosine deaminase activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0004032 aldose reductase (NADPH) activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0005049 nuclear export signal receptor activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0005078 MAP-kinase scaffold activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0005247 voltage-gated chloride channel activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0005527 macrolide binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0008179 adenylate cyclase binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0015166 polyol transmembrane transporter activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0016423 tRNA (guanine) methyltransferase activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0017166 vinculin binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0035197 siRNA binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0042301 phosphate ion binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0045295 gamma-catenin binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:1990459 transferrin receptor binding 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:1990817 poly(A) RNA polymerase activity 1/1556 12/18639 0.0833333333333333 0.99823264781491 0.648796966493122 0.880510168812095 GO:0050750 low-density lipoprotein particle receptor binding 2/1556 26/18639 0.0769230769230769 0.921445521059917 0.650992385064982 0.88142543725504 GO:0120014 phospholipid transfer activity 2/1556 26/18639 0.0769230769230769 0.921445521059917 0.650992385064982 0.88142543725504 GO:0051018 protein kinase A binding 4/1556 53/18639 0.0754716981132075 0.904059756511617 0.655911037706912 0.887048882966524 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1556 40/18639 0.075 0.898409383033419 0.660217208006213 0.88947101727965 GO:0140463 chromatin-protein adaptor activity 4/1556 54/18639 0.0740740740740741 0.887317909168809 0.670487383332888 0.88947101727965 GO:0005385 zinc ion transmembrane transporter activity 2/1556 27/18639 0.0740740740740741 0.887317909168809 0.671502036825422 0.88947101727965 GO:0008266 poly(U) RNA binding 2/1556 27/18639 0.0740740740740741 0.887317909168809 0.671502036825422 0.88947101727965 GO:0008320 protein transmembrane transporter activity 2/1556 27/18639 0.0740740740740741 0.887317909168809 0.671502036825422 0.88947101727965 GO:0008395 steroid hydroxylase activity 2/1556 27/18639 0.0740740740740741 0.887317909168809 0.671502036825422 0.88947101727965 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1556 27/18639 0.0740740740740741 0.887317909168809 0.671502036825422 0.88947101727965 GO:0001727 lipid kinase activity 3/1556 41/18639 0.0731707317073171 0.876496959056994 0.676760842826533 0.88947101727965 GO:0004465 lipoprotein lipase activity 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0031432 titin binding 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0031994 insulin-like growth factor I binding 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0039706 co-receptor binding 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0045159 myosin II binding 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0061459 L-arginine transmembrane transporter activity 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0070700 BMP receptor binding 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0071837 HMG box domain binding 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0140333 glycerophospholipid flippase activity 1/1556 13/18639 0.0769230769230769 0.921445521059917 0.678134590379776 0.88947101727965 GO:0033192 calmodulin-dependent protein phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0140791 histone H2AXS140 phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:1990439 MAP kinase serine/threonine phosphatase activity 6/1556 81/18639 0.0740740740740741 0.887317909168809 0.678884649582675 0.88947101727965 GO:0015631 tubulin binding 30/1556 385/18639 0.0779220779220779 0.933412346008747 0.681687773706955 0.88947101727965 GO:0005216 monoatomic ion channel activity 35/1556 448/18639 0.078125 0.935843107326478 0.685776894901393 0.88947101727965 GO:0004843 cysteine-type deubiquitinase activity 8/1556 108/18639 0.0740740740740741 0.887317909168809 0.688945405757834 0.88947101727965 GO:0051082 unfolded protein binding 9/1556 121/18639 0.0743801652892562 0.890984512099259 0.689361010412454 0.88947101727965 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 6/1556 82/18639 0.0731707317073171 0.876496959056994 0.690409224458421 0.88947101727965 GO:0033549 MAP kinase phosphatase activity 6/1556 82/18639 0.0731707317073171 0.876496959056994 0.690409224458421 0.88947101727965 GO:0005242 inward rectifier potassium channel activity 2/1556 28/18639 0.0714285714285714 0.855627983841352 0.691022214611256 0.88947101727965 GO:0008527 taste receptor activity 2/1556 28/18639 0.0714285714285714 0.855627983841352 0.691022214611256 0.88947101727965 GO:0019789 SUMO transferase activity 2/1556 28/18639 0.0714285714285714 0.855627983841352 0.691022214611256 0.88947101727965 GO:0045499 chemorepellent activity 2/1556 28/18639 0.0714285714285714 0.855627983841352 0.691022214611256 0.88947101727965 GO:0051393 alpha-actinin binding 2/1556 28/18639 0.0714285714285714 0.855627983841352 0.691022214611256 0.88947101727965 GO:0097718 disordered domain specific binding 2/1556 28/18639 0.0714285714285714 0.855627983841352 0.691022214611256 0.88947101727965 GO:0004520 DNA endonuclease activity 3/1556 42/18639 0.0714285714285714 0.855627983841352 0.692700572320477 0.88947101727965 GO:0008307 structural constituent of muscle 3/1556 42/18639 0.0714285714285714 0.855627983841352 0.692700572320477 0.88947101727965 GO:0016859 cis-trans isomerase activity 3/1556 42/18639 0.0714285714285714 0.855627983841352 0.692700572320477 0.88947101727965 GO:0019894 kinesin binding 3/1556 42/18639 0.0714285714285714 0.855627983841352 0.692700572320477 0.88947101727965 GO:0043175 RNA polymerase core enzyme binding 3/1556 42/18639 0.0714285714285714 0.855627983841352 0.692700572320477 0.88947101727965 GO:0015297 antiporter activity 10/1556 135/18639 0.0740740740740741 0.887317909168809 0.699144088732447 0.88947101727965 GO:0016407 acetyltransferase activity 7/1556 96/18639 0.0729166666666667 0.873453566838046 0.699699982618295 0.88947101727965 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/1556 83/18639 0.072289156626506 0.865936754731006 0.701657034808118 0.88947101727965 GO:0004705 JUN kinase activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0005313 L-glutamate transmembrane transporter activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0005347 ATP transmembrane transporter activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0008174 mRNA methyltransferase activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0008559 ABC-type xenobiotic transporter activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0015926 glucosidase activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0031404 chloride ion binding 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0034236 protein kinase A catalytic subunit binding 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0042043 neurexin family protein binding 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0043176 amine binding 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0046030 inositol trisphosphate phosphatase activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0061783 peptidoglycan muralytic activity 1/1556 14/18639 0.0714285714285714 0.855627983841352 0.705022949521249 0.88947101727965 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1556 70/18639 0.0714285714285714 0.855627983841352 0.705283748817945 0.88947101727965 GO:0016779 nucleotidyltransferase activity 10/1556 136/18639 0.0735294117647059 0.880793512777862 0.7078890612869 0.891344936813149 GO:0008509 monoatomic anion transmembrane transporter activity 11/1556 149/18639 0.0738255033557047 0.884340332292403 0.708307753930035 0.891344936813149 GO:0016417 S-acyltransferase activity 2/1556 29/18639 0.0689655172413793 0.826123570605443 0.709575079264783 0.891971276429375 GO:0017018 myosin phosphatase activity 6/1556 84/18639 0.0714285714285714 0.855627983841352 0.712626091615354 0.894836013198478 GO:0005261 monoatomic cation channel activity 26/1556 341/18639 0.0762463343108504 0.913338962223613 0.715186258110108 0.897078867045038 GO:0005267 potassium channel activity 9/1556 124/18639 0.0725806451612903 0.869428435193631 0.716910758799318 0.898269804809092 GO:0008408 3'-5' exonuclease activity 4/1556 58/18639 0.0689655172413793 0.826123570605443 0.724466345309924 0.899663148063021 GO:0008187 poly-pyrimidine tract binding 2/1556 30/18639 0.0666666666666667 0.798586118251928 0.727185987621247 0.899663148063021 GO:0033612 receptor serine/threonine kinase binding 2/1556 30/18639 0.0666666666666667 0.798586118251928 0.727185987621247 0.899663148063021 GO:0000774 adenyl-nucleotide exchange factor activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0010181 FMN binding 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0015116 sulfate transmembrane transporter activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0015250 water channel activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0030553 cGMP binding 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0034483 heparan sulfate sulfotransferase activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0140161 monocarboxylate:sodium symporter activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0141050 histone H3K deacetylase activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0141051 histone H4K deacetylase activity 1/1556 15/18639 0.0666666666666667 0.798586118251928 0.729666401362588 0.899663148063021 GO:0019783 ubiquitin-like protein peptidase activity 9/1556 127/18639 0.0708661417322835 0.848890755622128 0.74281361286146 0.914858732781318 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/1556 60/18639 0.0666666666666667 0.798586118251928 0.748866880998363 0.914858732781318 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1556 46/18639 0.0652173913043478 0.781225550463843 0.75051637200974 0.914858732781318 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1556 46/18639 0.0652173913043478 0.781225550463843 0.75051637200974 0.914858732781318 GO:0000062 fatty-acyl-CoA binding 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0004707 MAP kinase activity 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0005159 insulin-like growth factor receptor binding 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0008296 3'-5'-DNA exonuclease activity 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0015378 sodium:chloride symporter activity 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0015562 efflux transmembrane transporter activity 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0019841 retinol binding 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0022858 alanine transmembrane transporter activity 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1556 16/18639 0.0625 0.748674485861183 0.752252262588952 0.914858732781318 GO:0101005 deubiquitinase activity 8/1556 115/18639 0.0695652173913043 0.833307253828099 0.753852825020617 0.915844260166557 GO:0031369 translation initiation factor binding 2/1556 32/18639 0.0625 0.748674485861183 0.759695311138149 0.919088586230809 GO:0042910 xenobiotic transmembrane transporter activity 2/1556 32/18639 0.0625 0.748674485861183 0.759695311138149 0.919088586230809 GO:0047498 calcium-dependent phospholipase A2 activity 2/1556 32/18639 0.0625 0.748674485861183 0.759695311138149 0.919088586230809 GO:0070717 poly-purine tract binding 2/1556 32/18639 0.0625 0.748674485861183 0.759695311138149 0.919088586230809 GO:0140938 histone H3 methyltransferase activity 3/1556 47/18639 0.0638297872340425 0.764603730241208 0.763524935307034 0.922758498457614 GO:0004549 tRNA-specific ribonuclease activity 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:0004659 prenyltransferase activity 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:0016018 cyclosporin A binding 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:0017110 nucleoside diphosphate phosphatase activity 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:0032977 membrane insertase activity 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:1901567 fatty acid derivative binding 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:1990226 histone methyltransferase binding 1/1556 17/18639 0.0588235294117647 0.704634810222289 0.772952229265191 0.927382643600783 GO:0032266 phosphatidylinositol-3-phosphate binding 3/1556 48/18639 0.0625 0.748674485861183 0.775976750629109 0.930048659750918 GO:0008017 microtubule binding 20/1556 276/18639 0.072463768115942 0.86802838940427 0.77774869020901 0.931209433834962 GO:0015276 ligand-gated monoatomic ion channel activity 13/1556 186/18639 0.0698924731182796 0.837227382038311 0.786440507044115 0.937527623704138 GO:0140030 modification-dependent protein binding 12/1556 173/18639 0.069364161849711 0.830898851360388 0.788137660701661 0.937527623704138 GO:0015035 protein-disulfide reductase activity 2/1556 34/18639 0.0588235294117647 0.704634810222289 0.78879306646922 0.937527623704138 GO:0015079 potassium ion transmembrane transporter activity 11/1556 160/18639 0.06875 0.823541934447301 0.790339087837498 0.937527623704138 GO:0046982 protein heterodimerization activity 27/1556 369/18639 0.0731707317073171 0.876496959056994 0.791047218713846 0.937527623704138 GO:0005372 water transmembrane transporter activity 1/1556 18/18639 0.0555555555555556 0.665488431876607 0.791923678694004 0.937527623704138 GO:0008308 voltage-gated monoatomic anion channel activity 1/1556 18/18639 0.0555555555555556 0.665488431876607 0.791923678694004 0.937527623704138 GO:0015280 ligand-gated sodium channel activity 1/1556 18/18639 0.0555555555555556 0.665488431876607 0.791923678694004 0.937527623704138 GO:0015373 monoatomic anion:sodium symporter activity 1/1556 18/18639 0.0555555555555556 0.665488431876607 0.791923678694004 0.937527623704138 GO:0017128 phospholipid scramblase activity 1/1556 18/18639 0.0555555555555556 0.665488431876607 0.791923678694004 0.937527623704138 GO:0070628 proteasome binding 1/1556 18/18639 0.0555555555555556 0.665488431876607 0.791923678694004 0.937527623704138 GO:0022834 ligand-gated channel activity 13/1556 188/18639 0.0691489361702128 0.828320707761308 0.798658327089891 0.944286075538727 GO:0015605 organophosphate ester transmembrane transporter activity 3/1556 50/18639 0.06 0.718727506426735 0.799261984558663 0.944286075538727 GO:0022832 voltage-gated channel activity 12/1556 175/18639 0.0685714285714286 0.821402864487697 0.800708977763852 0.944343560671525 GO:0015108 chloride transmembrane transporter activity 8/1556 121/18639 0.0661157024793388 0.791986232977119 0.80137709103631 0.944343560671525 GO:0005343 organic acid:sodium symporter activity 2/1556 35/18639 0.0571428571428571 0.684502387073081 0.802143176562992 0.944343560671525 GO:0160215 deacylase activity 4/1556 65/18639 0.0615384615384615 0.737156416847934 0.802569807818337 0.944343560671525 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0008574 plus-end-directed microtubule motor activity 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0016918 retinal binding 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0120227 acyl-CoA binding 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0140036 ubiquitin-modified protein reader activity 1/1556 19/18639 0.0526315789473684 0.630462724935733 0.809310862838364 0.945551820759201 GO:0005272 sodium channel activity 3/1556 51/18639 0.0588235294117647 0.704634810222289 0.810123345999902 0.945551820759201 GO:0000993 RNA polymerase II complex binding 2/1556 36/18639 0.0555555555555556 0.665488431876607 0.814737998357258 0.946173687471004 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1556 36/18639 0.0555555555555556 0.665488431876607 0.814737998357258 0.946173687471004 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1556 36/18639 0.0555555555555556 0.665488431876607 0.814737998357258 0.946173687471004 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1556 36/18639 0.0555555555555556 0.665488431876607 0.814737998357258 0.946173687471004 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1556 36/18639 0.0555555555555556 0.665488431876607 0.814737998357258 0.946173687471004 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1556 67/18639 0.0597014925373134 0.715151747688294 0.821272702410949 0.952807869964254 GO:0010851 cyclase regulator activity 1/1556 20/18639 0.05 0.598939588688946 0.825246002334793 0.954551014676672 GO:0015095 magnesium ion transmembrane transporter activity 1/1556 20/18639 0.05 0.598939588688946 0.825246002334793 0.954551014676672 GO:0052745 inositol phosphate phosphatase activity 1/1556 20/18639 0.05 0.598939588688946 0.825246002334793 0.954551014676672 GO:0042805 actinin binding 2/1556 37/18639 0.0540540540540541 0.647502258042104 0.826610504640786 0.955176046738455 GO:0016853 isomerase activity 12/1556 180/18639 0.0666666666666667 0.798586118251928 0.829741994547415 0.957596809116026 GO:0016860 intramolecular oxidoreductase activity 3/1556 53/18639 0.0566037735849057 0.678044817383712 0.830357888836589 0.957596809116026 GO:0005254 chloride channel activity 5/1556 83/18639 0.0602409638554217 0.721613962275839 0.832889670601208 0.959561757680716 GO:0005249 voltage-gated potassium channel activity 6/1556 98/18639 0.0612244897959184 0.733395414721158 0.837218129418604 0.959947224244058 GO:0005109 frizzled binding 2/1556 38/18639 0.0526315789473684 0.630462724935733 0.837793430048296 0.959947224244058 GO:0005248 voltage-gated sodium channel activity 1/1556 21/18639 0.0476190476190476 0.570418655894234 0.839850289373144 0.959947224244058 GO:0008373 sialyltransferase activity 1/1556 21/18639 0.0476190476190476 0.570418655894234 0.839850289373144 0.959947224244058 GO:0009975 cyclase activity 1/1556 21/18639 0.0476190476190476 0.570418655894234 0.839850289373144 0.959947224244058 GO:0015174 basic amino acid transmembrane transporter activity 1/1556 21/18639 0.0476190476190476 0.570418655894234 0.839850289373144 0.959947224244058 GO:0036122 BMP binding 1/1556 21/18639 0.0476190476190476 0.570418655894234 0.839850289373144 0.959947224244058 GO:0061891 calcium ion sensor activity 1/1556 21/18639 0.0476190476190476 0.570418655894234 0.839850289373144 0.959947224244058 GO:0022836 gated channel activity 22/1556 318/18639 0.0691823899371069 0.828721443468982 0.849694143522513 0.968559394072256 GO:0022843 voltage-gated monoatomic cation channel activity 9/1556 143/18639 0.0629370629370629 0.753909971776296 0.853187136468154 0.968559394072256 GO:0004407 histone deacetylase activity 1/1556 22/18639 0.0454545454545455 0.544490535171769 0.853234807030003 0.968559394072256 GO:0008093 cytoskeletal anchor activity 1/1556 22/18639 0.0454545454545455 0.544490535171769 0.853234807030003 0.968559394072256 GO:0033558 protein lysine deacetylase activity 1/1556 22/18639 0.0454545454545455 0.544490535171769 0.853234807030003 0.968559394072256 GO:0140035 ubiquitin-like protein reader activity 1/1556 22/18639 0.0454545454545455 0.544490535171769 0.853234807030003 0.968559394072256 GO:0140784 metal ion sensor activity 1/1556 22/18639 0.0454545454545455 0.544490535171769 0.853234807030003 0.968559394072256 GO:0071949 FAD binding 2/1556 40/18639 0.05 0.598939588688946 0.858219179707067 0.973264216517114 GO:0005244 voltage-gated monoatomic ion channel activity 11/1556 173/18639 0.0635838150289017 0.761657280413689 0.864091483900436 0.974845568669949 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1556 23/18639 0.0434782608695652 0.520817033642562 0.865501372011542 0.974845568669949 GO:0003887 DNA-directed DNA polymerase activity 1/1556 23/18639 0.0434782608695652 0.520817033642562 0.865501372011542 0.974845568669949 GO:0005283 amino acid:sodium symporter activity 1/1556 23/18639 0.0434782608695652 0.520817033642562 0.865501372011542 0.974845568669949 GO:0031681 G-protein beta-subunit binding 1/1556 23/18639 0.0434782608695652 0.520817033642562 0.865501372011542 0.974845568669949 GO:0070577 lysine-acetylated histone binding 1/1556 23/18639 0.0434782608695652 0.520817033642562 0.865501372011542 0.974845568669949 GO:0099186 structural constituent of postsynapse 1/1556 23/18639 0.0434782608695652 0.520817033642562 0.865501372011542 0.974845568669949 GO:0004722 protein serine/threonine phosphatase activity 6/1556 103/18639 0.058252427184466 0.697793695559937 0.869500724180423 0.978399358568068 GO:0070840 dynein complex binding 1/1556 24/18639 0.0416666666666667 0.499116323907455 0.876743307182902 0.984637105644364 GO:0140033 acetylation-dependent protein binding 1/1556 24/18639 0.0416666666666667 0.499116323907455 0.876743307182902 0.984637105644364 GO:0005245 voltage-gated calcium channel activity 2/1556 43/18639 0.0465116279069767 0.557153105757159 0.88447210489538 0.992355440052029 GO:0004497 monooxygenase activity 6/1556 106/18639 0.0566037735849057 0.678044817383712 0.886177476570154 0.992864159911488 GO:0008483 transaminase activity 1/1556 25/18639 0.04 0.479151670951157 0.887046149730493 0.992864159911488 GO:0003697 single-stranded DNA binding 7/1556 121/18639 0.0578512396694215 0.692987953854979 0.887495487203021 0.992864159911488 GO:0015103 inorganic anion transmembrane transporter activity 10/1556 165/18639 0.0606060606060606 0.725987380229026 0.890989876430712 0.995812214834325 GO:0061659 ubiquitin-like protein ligase activity 25/1556 372/18639 0.0672043010752688 0.805026328882992 0.89569334949617 0.998107531284855 GO:0005112 Notch binding 1/1556 26/18639 0.0384615384615385 0.460722760529959 0.896488300317113 0.998107531284855 GO:0008143 poly(A) binding 1/1556 26/18639 0.0384615384615385 0.460722760529959 0.896488300317113 0.998107531284855 GO:0015216 purine nucleotide transmembrane transporter activity 1/1556 26/18639 0.0384615384615385 0.460722760529959 0.896488300317113 0.998107531284855 GO:0051539 4 iron, 4 sulfur cluster binding 2/1556 45/18639 0.0444444444444444 0.532390745501285 0.899391666691197 0.999999999879795 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1556 27/18639 0.037037037037037 0.443658954584404 0.905141618143717 0.999999999879795 GO:0030276 clathrin binding 2/1556 46/18639 0.0434782608695652 0.520817033642562 0.906158725540355 0.999999999879795 GO:0016887 ATP hydrolysis activity 28/1556 417/18639 0.0671462829736211 0.804331342124244 0.908078389679593 0.999999999879795 GO:0099095 ligand-gated monoatomic anion channel activity 2/1556 47/18639 0.0425531914893617 0.509735820160805 0.91249800510628 0.999999999879795 GO:0051537 2 iron, 2 sulfur cluster binding 1/1556 28/18639 0.0357142857142857 0.427813991920676 0.913071966422697 0.999999999879795 GO:0003713 transcription coactivator activity 16/1556 256/18639 0.0625 0.748674485861183 0.913921827364993 0.999999999879795 GO:0008170 N-methyltransferase activity 5/1556 98/18639 0.0510204081632653 0.611162845600965 0.920055848694617 0.999999999879795 GO:0005416 amino acid:monoatomic cation symporter activity 1/1556 29/18639 0.0344827586206897 0.413061785302721 0.920339712392622 0.999999999879795 GO:0035250 UDP-galactosyltransferase activity 1/1556 29/18639 0.0344827586206897 0.413061785302721 0.920339712392622 0.999999999879795 GO:0019787 ubiquitin-like protein transferase activity 32/1556 479/18639 0.0668058455114822 0.800253312653289 0.925940864256318 0.999999999879795 GO:0042054 histone methyltransferase activity 3/1556 67/18639 0.0447761194029851 0.53636381076622 0.926378060978172 0.999999999879795 GO:0015215 nucleotide transmembrane transporter activity 1/1556 30/18639 0.0333333333333333 0.399293059125964 0.927000185660601 0.999999999879795 GO:0031624 ubiquitin conjugating enzyme binding 1/1556 30/18639 0.0333333333333333 0.399293059125964 0.927000185660601 0.999999999879795 GO:0098918 structural constituent of synapse 1/1556 30/18639 0.0333333333333333 0.399293059125964 0.927000185660601 0.999999999879795 GO:0016755 aminoacyltransferase activity 33/1556 496/18639 0.0665322580645161 0.796976065594162 0.932407068787538 0.999999999879795 GO:0005184 neuropeptide hormone activity 1/1556 31/18639 0.032258064516129 0.386412637863836 0.933104098343287 0.999999999879795 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1556 31/18639 0.032258064516129 0.386412637863836 0.933104098343287 0.999999999879795 GO:0005452 solute:inorganic anion antiporter activity 1/1556 31/18639 0.032258064516129 0.386412637863836 0.933104098343287 0.999999999879795 GO:0017147 Wnt-protein binding 1/1556 31/18639 0.032258064516129 0.386412637863836 0.933104098343287 0.999999999879795 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1556 31/18639 0.032258064516129 0.386412637863836 0.933104098343287 0.999999999879795 GO:0008080 N-acetyltransferase activity 3/1556 69/18639 0.0434782608695652 0.520817033642562 0.935020504175019 0.999999999879795 GO:0016279 protein-lysine N-methyltransferase activity 3/1556 69/18639 0.0434782608695652 0.520817033642562 0.935020504175019 0.999999999879795 GO:0050660 flavin adenine dinucleotide binding 4/1556 86/18639 0.0465116279069767 0.557153105757159 0.935791632385489 0.999999999879795 GO:0008378 galactosyltransferase activity 1/1556 32/18639 0.03125 0.374337242930591 0.938697930188614 0.999999999879795 GO:0015106 bicarbonate transmembrane transporter activity 1/1556 32/18639 0.03125 0.374337242930591 0.938697930188614 0.999999999879795 GO:0030515 snoRNA binding 1/1556 32/18639 0.03125 0.374337242930591 0.938697930188614 0.999999999879795 GO:0160041 neuropeptide activity 1/1556 32/18639 0.03125 0.374337242930591 0.938697930188614 0.999999999879795 GO:0016278 lysine N-methyltransferase activity 3/1556 70/18639 0.0428571428571429 0.513376790304811 0.938981384394541 0.999999999879795 GO:0017046 peptide hormone binding 2/1556 53/18639 0.0377358490566038 0.452029878255808 0.942832459784116 0.999999999879795 GO:0034212 protein N-acetyltransferase activity 2/1556 53/18639 0.0377358490566038 0.452029878255808 0.942832459784116 0.999999999879795 GO:0042923 neuropeptide binding 1/1556 33/18639 0.0303030303030303 0.362993690114513 0.943824281595424 0.999999999879795 GO:0016874 ligase activity 9/1556 167/18639 0.0538922155688623 0.645563628527008 0.944688242942723 0.999999999879795 GO:0017069 snRNA binding 2/1556 54/18639 0.037037037037037 0.443658954584404 0.946796706844306 0.999999999879795 GO:0008175 tRNA methyltransferase activity 1/1556 34/18639 0.0294117647058824 0.352317405111145 0.948522197205309 0.999999999879795 GO:0015020 glucuronosyltransferase activity 1/1556 34/18639 0.0294117647058824 0.352317405111145 0.948522197205309 0.999999999879795 GO:0019825 oxygen binding 1/1556 34/18639 0.0294117647058824 0.352317405111145 0.948522197205309 0.999999999879795 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1556 34/18639 0.0294117647058824 0.352317405111145 0.948522197205309 0.999999999879795 GO:0031491 nucleosome binding 3/1556 74/18639 0.0405405405405405 0.485626693531578 0.952690140627497 0.999999999879795 GO:0034061 DNA polymerase activity 1/1556 35/18639 0.0285714285714286 0.342251193536541 0.952827462518319 0.999999999879795 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/1556 36/18639 0.0277777777777778 0.332744215938303 0.956772875780063 0.999999999879795 GO:0055106 ubiquitin-protein transferase regulator activity 1/1556 36/18639 0.0277777777777778 0.332744215938303 0.956772875780063 0.999999999879795 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/1556 57/18639 0.0350877192982456 0.420308483290488 0.957175934125825 0.999999999879795 GO:0051536 iron-sulfur cluster binding 3/1556 76/18639 0.0394736842105263 0.472847043701799 0.958410689136277 0.999999999879795 GO:0016410 N-acyltransferase activity 4/1556 94/18639 0.0425531914893617 0.509735820160805 0.959712897987018 0.999999999879795 GO:0019213 deacetylase activity 1/1556 37/18639 0.027027027027027 0.323751129021052 0.960388497200599 0.999999999879795 GO:0022829 wide pore channel activity 1/1556 37/18639 0.027027027027027 0.323751129021052 0.960388497200599 0.999999999879795 GO:0003724 RNA helicase activity 3/1556 77/18639 0.038961038961039 0.466706173004374 0.961021325897968 0.999999999879795 GO:0051540 metal cluster binding 3/1556 77/18639 0.038961038961039 0.466706173004374 0.961021325897968 0.999999999879795 GO:0004842 ubiquitin-protein transferase activity 28/1556 449/18639 0.0623608017817372 0.747007059389331 0.962195214509102 0.999999999879795 GO:0061630 ubiquitin protein ligase activity 21/1556 353/18639 0.0594900849858357 0.712619340649738 0.964508248791808 0.999999999879795 GO:0015293 symporter activity 7/1556 146/18639 0.0479452054794521 0.5743256329894 0.965199096705275 0.999999999879795 GO:0008186 ATP-dependent activity, acting on RNA 3/1556 79/18639 0.0379746835443038 0.454890826852364 0.965787073212872 0.999999999879795 GO:0000217 DNA secondary structure binding 1/1556 39/18639 0.0256410256410256 0.307148507019972 0.96673826676948 0.999999999879795 GO:0016836 hydro-lyase activity 2/1556 61/18639 0.0327868852459016 0.39274727127144 0.968034155119888 0.999999999879795 GO:0015081 sodium ion transmembrane transporter activity 8/1556 164/18639 0.0487804878048781 0.584331306037996 0.968704753726518 0.999999999879795 GO:0015294 solute:monoatomic cation symporter activity 5/1556 116/18639 0.0431034482758621 0.516327231628402 0.969872397702278 0.999999999879795 GO:0008135 translation factor activity, RNA binding 3/1556 83/18639 0.036144578313253 0.432968377365503 0.973717389156303 0.999999999879795 GO:0031492 nucleosomal DNA binding 1/1556 42/18639 0.0238095238095238 0.285209327947117 0.974407410865399 0.999999999879795 GO:0180051 translation factor activity 3/1556 84/18639 0.0357142857142857 0.427813991920676 0.975408206740566 0.999999999879795 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1556 43/18639 0.0232558139534884 0.27857655287858 0.976548727674209 0.999999999879795 GO:0140104 molecular carrier activity 13/1556 249/18639 0.0522088353413655 0.625398767305727 0.978095937269627 0.999999999879795 GO:0019205 nucleobase-containing compound kinase activity 1/1556 44/18639 0.0227272727272727 0.272245267585885 0.978510987285896 0.999999999879795 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/1556 122/18639 0.040983606557377 0.4909340890893 0.978628744418232 0.999999999879795 GO:0140767 enzyme-substrate adaptor activity 6/1556 139/18639 0.0431654676258993 0.517070148508443 0.978651478139943 0.999999999879795 GO:0008173 RNA methyltransferase activity 2/1556 67/18639 0.0298507462686567 0.357575873844147 0.979505120599661 0.999999999879795 GO:0061733 protein-lysine-acetyltransferase activity 1/1556 47/18639 0.0212765957446809 0.254867910080403 0.983466917820933 0.999999999879795 GO:0061749 forked DNA-dependent helicase activity 1/1556 47/18639 0.0212765957446809 0.254867910080403 0.983466917820933 0.999999999879795 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1556 47/18639 0.0212765957446809 0.254867910080403 0.983466917820933 0.999999999879795 GO:0140299 molecular sensor activity 2/1556 71/18639 0.028169014084507 0.337430754190956 0.984813672616088 0.999999999879795 GO:0009378 four-way junction helicase activity 1/1556 48/18639 0.0208333333333333 0.249558161953728 0.984850603054938 0.999999999879795 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/1556 48/18639 0.0208333333333333 0.249558161953728 0.984850603054938 0.999999999879795 GO:0036121 double-stranded DNA helicase activity 1/1556 48/18639 0.0208333333333333 0.249558161953728 0.984850603054938 0.999999999879795 GO:0043138 3'-5' DNA helicase activity 1/1556 48/18639 0.0208333333333333 0.249558161953728 0.984850603054938 0.999999999879795 GO:0140713 histone chaperone activity 7/1556 164/18639 0.0426829268292683 0.511289892783247 0.986350588864848 0.999999999879795 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/1556 73/18639 0.0273972602739726 0.328186075993943 0.986939815680905 0.999999999879795 GO:0003730 mRNA 3'-UTR binding 13/1556 262/18639 0.049618320610687 0.594367530760023 0.987520158705982 0.999999999879795 GO:0042393 histone binding 12/1556 247/18639 0.048582995951417 0.581965592248369 0.987836728545547 0.999999999879795 GO:0003684 damaged DNA binding 2/1556 74/18639 0.027027027027027 0.323751129021052 0.9878911955435 0.999999999879795 GO:0035064 methylated histone binding 2/1556 74/18639 0.027027027027027 0.323751129021052 0.9878911955435 0.999999999879795 GO:0008276 protein methyltransferase activity 3/1556 95/18639 0.0315789473684211 0.37827763496144 0.98832582217996 0.999999999879795 GO:0003743 translation initiation factor activity 1/1556 51/18639 0.0196078431372549 0.234878270074096 0.988345138839678 0.999999999879795 GO:0016597 amino acid binding 1/1556 51/18639 0.0196078431372549 0.234878270074096 0.988345138839678 0.999999999879795 GO:0000510 H3-H4 histone complex chaperone activity 6/1556 151/18639 0.0397350993377483 0.475978481077308 0.989093656784369 0.999999999879795 GO:0140584 chromatin extrusion motor activity 6/1556 151/18639 0.0397350993377483 0.475978481077308 0.989093656784369 0.999999999879795 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 6/1556 151/18639 0.0397350993377483 0.475978481077308 0.989093656784369 0.999999999879795 GO:0140849 ATP-dependent H2AZ histone chaperone activity 6/1556 151/18639 0.0397350993377483 0.475978481077308 0.989093656784369 0.999999999879795 GO:0140098 catalytic activity, acting on RNA 21/1556 387/18639 0.0542635658914729 0.650011956716686 0.989502287203625 0.999999999879795 GO:0140034 methylation-dependent protein binding 2/1556 76/18639 0.0263157894736842 0.315231362467866 0.9895955348295 0.999999999879795 GO:0015616 DNA translocase activity 6/1556 152/18639 0.0394736842105263 0.472847043701799 0.989700256959956 0.999999999879795 GO:0140674 ATP-dependent histone chaperone activity 6/1556 152/18639 0.0394736842105263 0.472847043701799 0.989700256959956 0.999999999879795 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/1556 53/18639 0.0188679245283019 0.226014939127904 0.990214772234729 0.999999999879795 GO:0061775 cohesin loader activity 6/1556 153/18639 0.0392156862745098 0.469756540148193 0.99027490090002 0.999999999879795 GO:0140597 protein carrier chaperone 8/1556 188/18639 0.0425531914893617 0.509735820160805 0.99073292304769 0.999999999879795 GO:0004386 helicase activity 6/1556 155/18639 0.0387096774193548 0.463695165436603 0.99133449170883 0.999999999879795 GO:0015370 solute:sodium symporter activity 2/1556 79/18639 0.0253164556962025 0.303260551234909 0.99172145345449 0.999999999879795 GO:0016835 carbon-oxygen lyase activity 2/1556 79/18639 0.0253164556962025 0.303260551234909 0.99172145345449 0.999999999879795 GO:0000049 tRNA binding 2/1556 80/18639 0.025 0.299469794344473 0.992330759475694 0.999999999879795 GO:0140658 ATP-dependent chromatin remodeler activity 6/1556 158/18639 0.0379746835443038 0.454890826852364 0.992721054243136 0.999999999879795 GO:0003689 DNA clamp loader activity 6/1556 160/18639 0.0375 0.449204691516709 0.993525435095887 0.999999999879795 GO:0017116 single-stranded DNA helicase activity 1/1556 58/18639 0.0172413793103448 0.206530892651361 0.99368034803836 0.999999999879795 GO:0036002 pre-mRNA binding 1/1556 59/18639 0.0169491525423729 0.2030303690471 0.994209564897104 0.999999999879795 GO:0001653 peptide receptor activity 4/1556 128/18639 0.03125 0.374337242930591 0.99528102926981 0.999999999879795 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/1556 167/18639 0.0359281437125748 0.430375752351338 0.995724883581743 0.999999999879795 GO:0019843 rRNA binding 1/1556 65/18639 0.0153846153846154 0.184289104211983 0.99657410103039 0.999999999879795 GO:0003777 microtubule motor activity 1/1556 68/18639 0.0147058823529412 0.176158702555572 0.997365019706676 0.999999999879795 GO:0140223 general transcription initiation factor activity 1/1556 68/18639 0.0147058823529412 0.176158702555572 0.997365019706676 0.999999999879795 GO:0140101 catalytic activity, acting on a tRNA 4/1556 139/18639 0.0287769784172662 0.344713432338962 0.997742141776716 0.999999999879795 GO:0030594 neurotransmitter receptor activity 2/1556 97/18639 0.0206185567010309 0.246985397397503 0.997945081662163 0.999999999879795 GO:0008528 G protein-coupled peptide receptor activity 3/1556 122/18639 0.0245901639344262 0.29456045345358 0.998276982034345 0.999999999879795 GO:0003678 DNA helicase activity 1/1556 74/18639 0.0135135135135135 0.161875564510526 0.998441433753007 0.999999999879795 GO:0008168 methyltransferase activity 7/1556 204/18639 0.0343137254901961 0.411036972629669 0.99861161475225 0.999999999879795 GO:0140097 catalytic activity, acting on DNA 14/1556 336/18639 0.0416666666666667 0.499116323907455 0.999211725603513 0.999999999879795 GO:0016741 transferase activity, transferring one-carbon groups 7/1556 215/18639 0.0325581395348837 0.390007174030011 0.999288547875932 0.999999999879795 GO:0008094 ATP-dependent activity, acting on DNA 6/1556 210/18639 0.0285714285714286 0.342251193536541 0.99971272222505 0.999999999879795 GO:0045182 translation regulator activity 8/1556 356/18639 0.0224719101123595 0.269186331995032 0.999999752690453 0.999999999879795 GO:0030371 translation repressor activity 6/1556 329/18639 0.0182370820668693 0.218458208640345 0.999999931743024 0.999999999879795 GO:1903231 mRNA base-pairing translational repressor activity 2/1556 298/18639 0.00671140939597315 0.0803945756629458 0.999999999879795 0.999999999879795