ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0023026	MHC class II protein complex binding	18/1388	27/18639	0.666666666666667	8.95244956772334	1.09538363155262e-14	1.27502654712724e-11
GO:0023023	MHC protein complex binding	19/1388	37/18639	0.513513513513513	6.89580574811122	1.58347952543083e-12	9.21585083800741e-10
GO:0042605	peptide antigen binding	19/1388	45/18639	0.422222222222222	5.66988472622478	1.22657097785837e-10	4.75909539409047e-08
GO:0019003	GDP binding	23/1388	75/18639	0.306666666666667	4.11812680115274	2.60429640215004e-09	6.21609052813492e-07
GO:0042277	peptide binding	47/1388	249/18639	0.188755020080321	2.53472969688552	2.6701419794394e-09	6.21609052813492e-07
GO:0044389	ubiquitin-like protein ligase binding	55/1388	322/18639	0.170807453416149	2.29371766874899	5.35348169300514e-09	1.038575448443e-06
GO:0031625	ubiquitin protein ligase binding	50/1388	302/18639	0.165562913907285	2.22329045556043	7.35222784941402e-08	1.22257045953113e-05
GO:0031072	heat shock protein binding	29/1388	131/18639	0.221374045801527	2.97275997096157	8.56027268634555e-08	1.24551967586328e-05
GO:0140297	DNA-binding transcription factor binding	69/1388	488/18639	0.141393442622951	1.89872649643313	1.78701557207841e-07	2.12945401577214e-05
GO:0046332	SMAD binding	21/1388	79/18639	0.265822784810127	3.56964761244665	1.98950495356536e-07	2.12945401577214e-05
GO:0003925	G protein activity	17/1388	54/18639	0.314814814814815	4.22754562920269	2.01237063346165e-07	2.12945401577214e-05
GO:0140313	molecular sequestering activity	17/1388	55/18639	0.309090909090909	4.15068116321719	2.71172735196215e-07	2.63037553140329e-05
GO:0140375	immune receptor activity	31/1388	156/18639	0.198717948717949	2.6685186211483	4.08825882677157e-07	3.66056405720162e-05
GO:0032395	MHC class II receptor activity	7/1388	10/18639	0.7	9.40007204610951	1.22910874443861e-06	9.93059777311242e-05
GO:0003924	GTPase activity	50/1388	331/18639	0.151057401812689	2.02850065733913	1.27971620787531e-06	9.93059777311242e-05
GO:0005543	phospholipid binding	67/1388	497/18639	0.134808853118712	1.81030418824184	1.52765279638185e-06	0.00011113674093678
GO:0140311	protein sequestering activity	12/1388	33/18639	0.363636363636364	4.88315430966728	2.25463562387723e-06	0.000154376227423124
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	51/1388	349/18639	0.146131805157593	1.96235642387059	2.71466838213576e-06	0.000171697915778797
GO:0005525	GTP binding	54/1388	378/18639	0.142857142857143	1.91838205022643	2.80262920944771e-06	0.000171697915778797
GO:0019001	guanyl nucleotide binding	56/1388	400/18639	0.14	1.8800144092219	3.46572499434396e-06	0.000176009265288273
GO:0032561	guanyl ribonucleotide binding	56/1388	400/18639	0.14	1.8800144092219	3.46572499434396e-06	0.000176009265288273
GO:0038024	cargo receptor activity	17/1388	65/18639	0.261538461538462	3.51211483041454	3.63550665424766e-06	0.000176009265288273
GO:0042625	ATPase-coupled ion transmembrane transporter activity	10/1388	24/18639	0.416666666666667	5.59528097982709	3.7802677252636e-06	0.000176009265288273
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	10/1388	24/18639	0.416666666666667	5.59528097982709	3.7802677252636e-06	0.000176009265288273
GO:0046961	proton-transporting ATPase activity, rotational mechanism	10/1388	24/18639	0.416666666666667	5.59528097982709	3.7802677252636e-06	0.000176009265288273
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	15/1388	54/18639	0.277777777777778	3.73018731988473	6.0210436683262e-06	0.000269557493458911
GO:0003779	actin binding	59/1388	443/18639	0.133182844243792	1.78846904456776	9.28428100002945e-06	0.000400255669779048
GO:0001618	virus receptor activity	18/1388	81/18639	0.222222222222222	2.98414985590778	2.21782586194399e-05	0.000921981894036714
GO:0140272	exogenous protein binding	18/1388	82/18639	0.219512195121951	2.94775778449427	2.64617763180343e-05	0.00106212095290317
GO:0035091	phosphatidylinositol binding	41/1388	284/18639	0.144366197183099	1.93864664934854	3.34149906924412e-05	0.00129650163886672
GO:0045296	cadherin binding	46/1388	334/18639	0.137724550898204	1.84945814423027	3.8098299070412e-05	0.0014305296812245
GO:0060590	ATPase regulator activity	13/1388	49/18639	0.26530612244898	3.56270952184909	4.25972385754013e-05	0.00154947455318022
GO:0008238	exopeptidase activity	20/1388	102/18639	0.196078431372549	2.63307340227157	5.46047788483081e-05	0.00192605947210396
GO:0005126	cytokine receptor binding	39/1388	275/18639	0.141818181818182	1.90443018077024	7.63113395729514e-05	0.00261254115479163
GO:0030695	GTPase regulator activity	60/1388	489/18639	0.122699386503067	1.64769010448896	8.93557873606421e-05	0.00290820319916321
GO:0019207	kinase regulator activity	40/1388	287/18639	0.139372822299652	1.87159224412335	9.15540112388597e-05	0.00290820319916321
GO:0060589	nucleoside-triphosphatase regulator activity	60/1388	490/18639	0.122448979591837	1.64432747162265	9.46323707107248e-05	0.00290820319916321
GO:0061135	endopeptidase regulator activity	29/1388	184/18639	0.157608695652174	2.11647584889112	9.67330308521365e-05	0.00290820319916321
GO:0042626	ATPase-coupled transmembrane transporter activity	19/1388	98/18639	0.193877551020408	2.60351849673587	9.74397979101074e-05	0.00290820319916321
GO:0044183	protein folding chaperone	16/1388	75/18639	0.213333333333333	2.86478386167147	0.000104994235051672	0.00305533224000366
GO:0001540	amyloid-beta binding	17/1388	83/18639	0.204819277108434	2.75045137321621	0.000110364450459675	0.00313327366670881
GO:0051087	protein-folding chaperone binding	23/1388	134/18639	0.171641791044776	2.3049217170631	0.000135837980893314	0.00376465261332899
GO:0061134	peptidase regulator activity	33/1388	226/18639	0.146017699115044	1.96082413098365	0.000151333531132902	0.00409656349392321
GO:0051020	GTPase binding	42/1388	315/18639	0.133333333333333	1.79048991354467	0.000168440583187744	0.00445601906433032
GO:0051015	actin filament binding	31/1388	209/18639	0.148325358851675	1.99181294210113	0.00017772836826937	0.00459724045923438
GO:0004857	enzyme inhibitor activity	51/1388	416/18639	0.122596153846154	1.64630382675682	0.000298900010422796	0.00749028675065122
GO:0017124	SH3 domain binding	20/1388	115/18639	0.173913043478261	2.33542162636261	0.000302442849897429	0.00749028675065122
GO:0071813	lipoprotein particle binding	9/1388	32/18639	0.28125	3.77681466138329	0.000400179382952061	0.00937143687727757
GO:0071814	protein-lipid complex binding	9/1388	32/18639	0.28125	3.77681466138329	0.000400179382952061	0.00937143687727757
GO:0019955	cytokine binding	23/1388	144/18639	0.159722222222222	2.14485770893372	0.000402553130467249	0.00937143687727757
GO:0005041	low-density lipoprotein particle receptor activity	6/1388	15/18639	0.4	5.37146974063401	0.00046947623929991	0.0107151047557862
GO:0015485	cholesterol binding	12/1388	54/18639	0.222222222222222	2.98414985590778	0.000505468931049428	0.0113147276104141
GO:0001671	ATPase activator activity	8/1388	27/18639	0.296296296296296	3.97886647454371	0.000571021286446021	0.012540920328739
GO:0031267	small GTPase binding	37/1388	283/18639	0.130742049469965	1.75569240639097	0.000584059209137553	0.0125897207302984
GO:0019887	protein kinase regulator activity	34/1388	255/18639	0.133333333333333	1.79048991354467	0.000673361386731063	0.0142507755300901
GO:0000062	fatty-acyl-CoA binding	6/1388	16/18639	0.375	5.03575288184438	0.00070402723440269	0.0146337089436559
GO:0042608	T cell receptor binding	5/1388	11/18639	0.454545454545455	6.1039428870841	0.000717821100418033	0.0146586624716946
GO:0097718	disordered domain specific binding	8/1388	28/18639	0.285714285714286	3.83676410045286	0.000747725059572822	0.0150060684369442
GO:0000149	SNARE binding	18/1388	106/18639	0.169811320754717	2.28034092762764	0.000794936277372494	0.0156831496078234
GO:0005096	GTPase activator activity	35/1388	271/18639	0.129151291512915	1.73433063581356	0.00100893516270342	0.0194612154411124
GO:1901567	fatty acid derivative binding	6/1388	17/18639	0.352941176470588	4.73953212408883	0.0010198746923607	0.0194612154411124
GO:0043130	ubiquitin binding	17/1388	100/18639	0.17	2.28287463976945	0.00108396794054356	0.0200713548354591
GO:0030544	Hsp70 protein binding	11/1388	51/18639	0.215686274509804	2.89638074249873	0.00111584757331048	0.0200713548354591
GO:0022853	active monoatomic ion transmembrane transporter activity	19/1388	118/18639	0.161016949152542	2.16224417525521	0.00112181781152015	0.0200713548354591
GO:0003725	double-stranded RNA binding	14/1388	75/18639	0.186666666666667	2.50668587896254	0.0011482882608285	0.0200713548354591
GO:0035259	nuclear glucocorticoid receptor binding	5/1388	12/18639	0.416666666666667	5.59528097982709	0.00115530994327814	0.0200713548354591
GO:0070008	serine-type exopeptidase activity	5/1388	12/18639	0.416666666666667	5.59528097982709	0.00115530994327814	0.0200713548354591
GO:1901981	phosphatidylinositol phosphate binding	26/1388	185/18639	0.140540540540541	1.88727315211465	0.00128517600090933	0.0219991891920361
GO:0015399	primary active transmembrane transporter activity	24/1388	166/18639	0.144578313253012	1.94149508697615	0.00130840632119958	0.0220722457663233
GO:0032934	sterol binding	13/1388	68/18639	0.191176470588235	2.56724656721478	0.00135503406742592	0.0225322807783396
GO:0030228	lipoprotein particle receptor activity	6/1388	18/18639	0.333333333333333	4.47622478386167	0.00143411847649745	0.0232570872136824
GO:0046915	transition metal ion transmembrane transporter activity	10/1388	45/18639	0.222222222222222	2.98414985590778	0.00145856302972407	0.0232570872136824
GO:0141110	transporter inhibitor activity	10/1388	45/18639	0.222222222222222	2.98414985590778	0.00145856302972407	0.0232570872136824
GO:0051082	unfolded protein binding	19/1388	121/18639	0.15702479338843	2.10863481553814	0.00152181582552037	0.0239377516338609
GO:0004180	carboxypeptidase activity	10/1388	46/18639	0.217391304347826	2.91927703295326	0.00174133358495957	0.0263066957238879
GO:0008035	high-density lipoprotein particle binding	5/1388	13/18639	0.384615384615385	5.16487475060962	0.00176281981654919	0.0263066957238879
GO:0017154	semaphorin receptor activity	5/1388	13/18639	0.384615384615385	5.16487475060962	0.00176281981654919	0.0263066957238879
GO:0035325	Toll-like receptor binding	5/1388	13/18639	0.384615384615385	5.16487475060962	0.00176281981654919	0.0263066957238879
GO:0004866	endopeptidase inhibitor activity	23/1388	161/18639	0.142857142857143	1.91838205022643	0.00191415528661885	0.0281984120352269
GO:0120015	sterol transfer activity	8/1388	32/18639	0.25	3.35716858789625	0.00193803519142453	0.0281984120352269
GO:0120227	acyl-CoA binding	6/1388	19/18639	0.315789473684211	4.24063400576369	0.00196511811175293	0.0282394750874125
GO:0004177	aminopeptidase activity	9/1388	40/18639	0.225	3.02145172910663	0.00227412772516335	0.0318925864107246
GO:0140662	ATP-dependent protein folding chaperone	9/1388	40/18639	0.225	3.02145172910663	0.00227412772516335	0.0318925864107246
GO:0003823	antigen binding	24/1388	174/18639	0.137931034482759	1.85223094504621	0.00248921999032048	0.0344934770087266
GO:1990782	protein tyrosine kinase binding	18/1388	117/18639	0.153846153846154	2.06594990024385	0.002519017549397	0.0344957226764484
GO:0005545	1-phosphatidylinositol binding	5/1388	14/18639	0.357142857142857	4.79595512556608	0.00257517772534193	0.0348547310732326
GO:0042288	MHC class I protein binding	6/1388	20/18639	0.3	4.0286023054755	0.00263227348438661	0.0352180038600691
GO:0042287	MHC protein binding	9/1388	41/18639	0.219512195121951	2.94775778449427	0.00272445303370747	0.0360370833094942
GO:0005044	scavenger receptor activity	7/1388	27/18639	0.259259259259259	3.48150816522574	0.00295249168864446	0.038361122582913
GO:0033218	amide binding	31/1388	247/18639	0.125506072874494	1.68538018177788	0.00296606617909121	0.038361122582913
GO:0019209	kinase activator activity	21/1388	148/18639	0.141891891891892	1.90542000934652	0.00319384757226914	0.0401513479666266
GO:0035591	signaling adaptor activity	19/1388	129/18639	0.147286821705426	1.97786676496213	0.00321887942385593	0.0401513479666266
GO:0035198	miRNA binding	9/1388	42/18639	0.214285714285714	2.87757307533965	0.00324246280830146	0.0401513479666266
GO:0051879	Hsp90 protein binding	9/1388	42/18639	0.214285714285714	2.87757307533965	0.00324246280830146	0.0401513479666266
GO:0030414	peptidase inhibitor activity	23/1388	169/18639	0.136094674556213	1.82757106560033	0.0035877489311842	0.0439593658515622
GO:0017081	chloride channel regulator activity	5/1388	15/18639	0.333333333333333	4.47622478386167	0.00362802846836295	0.0439898451789008
GO:0008200	ion channel inhibitor activity	9/1388	43/18639	0.209302325581395	2.81065277126198	0.0038349079473914	0.0460188953686968
GO:0005484	SNAP receptor activity	8/1388	36/18639	0.222222222222222	2.98414985590778	0.0042755895949934	0.0499832025011226
GO:0061133	endopeptidase activator activity	6/1388	22/18639	0.272727272727273	3.66236573225046	0.0044564183176619	0.0499832025011226
GO:0005381	iron ion transmembrane transporter activity	4/1388	10/18639	0.4	5.37146974063401	0.00446498315727478	0.0499832025011226
GO:0030957	Tat protein binding	4/1388	10/18639	0.4	5.37146974063401	0.00446498315727478	0.0499832025011226
GO:0031996	thioesterase binding	4/1388	10/18639	0.4	5.37146974063401	0.00446498315727478	0.0499832025011226
GO:1905394	retromer complex binding	4/1388	10/18639	0.4	5.37146974063401	0.00446498315727478	0.0499832025011226
GO:0005080	protein kinase C binding	10/1388	52/18639	0.192307692307692	2.58243737530481	0.00450164254520013	0.0499832025011226
GO:0016248	channel inhibitor activity	9/1388	44/18639	0.204545454545455	2.74677429918784	0.00450879404004972	0.0499832025011226
GO:0004896	cytokine receptor activity	15/1388	96/18639	0.15625	2.09823036743516	0.00477793653330842	0.0524671521204812
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	11/1388	61/18639	0.180327868852459	2.421564227335	0.0049491807719322	0.0529365835617747
GO:0019905	syntaxin binding	11/1388	61/18639	0.180327868852459	2.421564227335	0.0049491807719322	0.0529365835617747
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	5/1388	16/18639	0.3125	4.19646073487032	0.00495711993834488	0.0529365835617747
GO:0043394	proteoglycan binding	8/1388	37/18639	0.216216216216216	2.90349715709946	0.00510579132943549	0.0540285555223901
GO:0015179	L-amino acid transmembrane transporter activity	11/1388	62/18639	0.17741935483871	2.38250673979734	0.00562128140833144	0.0577428242177227
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/1388	23/18639	0.260869565217391	3.50313243954392	0.00565522505225119	0.0577428242177227
GO:0004602	glutathione peroxidase activity	6/1388	23/18639	0.260869565217391	3.50313243954392	0.00565522505225119	0.0577428242177227
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	6/1388	23/18639	0.260869565217391	3.50313243954392	0.00565522505225119	0.0577428242177227
GO:0005092	GDP-dissociation inhibitor activity	5/1388	17/18639	0.294117647058824	3.94961010340736	0.00659763879083828	0.063102374344561
GO:0008429	phosphatidylethanolamine binding	5/1388	17/18639	0.294117647058824	3.94961010340736	0.00659763879083828	0.063102374344561
GO:0030169	low-density lipoprotein particle binding	5/1388	17/18639	0.294117647058824	3.94961010340736	0.00659763879083828	0.063102374344561
GO:0048038	quinone binding	5/1388	17/18639	0.294117647058824	3.94961010340736	0.00659763879083828	0.063102374344561
GO:0015173	aromatic amino acid transmembrane transporter activity	4/1388	11/18639	0.363636363636364	4.88315430966728	0.00660621861833579	0.063102374344561
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/1388	11/18639	0.363636363636364	4.88315430966728	0.00660621861833579	0.063102374344561
GO:0019864	IgG binding	4/1388	11/18639	0.363636363636364	4.88315430966728	0.00660621861833579	0.063102374344561
GO:0015101	organic cation transmembrane transporter activity	13/1388	81/18639	0.160493827160494	2.15521934037784	0.00661382274058114	0.063102374344561
GO:0070325	lipoprotein particle receptor binding	7/1388	31/18639	0.225806451612903	3.03228130519662	0.00673395155865031	0.0637261757257639
GO:0032182	ubiquitin-like protein binding	17/1388	120/18639	0.141666666666667	1.90239553314121	0.00762039216699078	0.0715333587288489
GO:0043178	alcohol binding	14/1388	92/18639	0.152173913043478	2.04349392306729	0.00794480341268983	0.0739820093789677
GO:0120013	lipid transfer activity	11/1388	65/18639	0.169230769230769	2.27254489026823	0.00807583692852355	0.0740268084777572
GO:0022884	macromolecule transmembrane transporter activity	7/1388	32/18639	0.21875	2.93752251440922	0.00807680814147351	0.0740268084777572
GO:0001664	G protein-coupled receptor binding	34/1388	297/18639	0.114478114478114	1.53728931971007	0.0081639296079829	0.0742407348725945
GO:0061791	GTPase motor activity	8/1388	40/18639	0.2	2.685734870317	0.00834340338720108	0.0747055503284773
GO:1990606	membrane scission GTPase motor activity	8/1388	40/18639	0.2	2.685734870317	0.00834340338720108	0.0747055503284773
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/1388	18/18639	0.277777777777778	3.73018731988473	0.00858360814250785	0.0751227058487153
GO:0016854	racemase and epimerase activity	5/1388	18/18639	0.277777777777778	3.73018731988473	0.00858360814250785	0.0751227058487153
GO:0034185	apolipoprotein binding	5/1388	18/18639	0.277777777777778	3.73018731988473	0.00858360814250785	0.0751227058487153
GO:0120020	cholesterol transfer activity	6/1388	25/18639	0.24	3.2228818443804	0.00873160351099012	0.0756489755826635
GO:0016504	peptidase activator activity	10/1388	57/18639	0.175438596491228	2.35590778097983	0.00877372139489654	0.0756489755826635
GO:0004860	protein kinase inhibitor activity	13/1388	84/18639	0.154761904761905	2.07824722107863	0.00897469425194256	0.0759585127316532
GO:0008235	metalloexopeptidase activity	11/1388	66/18639	0.166666666666667	2.23811239193084	0.00905628465952506	0.0759585127316532
GO:0004875	complement receptor activity	4/1388	12/18639	0.333333333333333	4.47622478386167	0.00933167295586461	0.0759585127316532
GO:0008603	cAMP-dependent protein kinase regulator activity	4/1388	12/18639	0.333333333333333	4.47622478386167	0.00933167295586461	0.0759585127316532
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/1388	12/18639	0.333333333333333	4.47622478386167	0.00933167295586461	0.0759585127316532
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/1388	12/18639	0.333333333333333	4.47622478386167	0.00933167295586461	0.0759585127316532
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/1388	12/18639	0.333333333333333	4.47622478386167	0.00933167295586461	0.0759585127316532
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/1388	12/18639	0.333333333333333	4.47622478386167	0.00933167295586461	0.0759585127316532
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/1388	41/18639	0.195121951219512	2.62022914177269	0.00970557316986617	0.0779123253084429
GO:0140318	protein transporter activity	8/1388	41/18639	0.195121951219512	2.62022914177269	0.00970557316986617	0.0779123253084429
GO:0061980	regulatory RNA binding	10/1388	58/18639	0.172413793103448	2.31528868130776	0.0099128152699572	0.0786442459515912
GO:0022804	active transmembrane transporter activity	48/1388	457/18639	0.105032822757112	1.410451573033	0.00993187642172156	0.0786442459515912
GO:0050750	low-density lipoprotein particle receptor binding	6/1388	26/18639	0.230769230769231	3.09892485036577	0.0106505625334204	0.0832030522745056
GO:0070006	metalloaminopeptidase activity	6/1388	26/18639	0.230769230769231	3.09892485036577	0.0106505625334204	0.0832030522745056
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/1388	86/18639	0.151162790697674	2.02991589035587	0.010884010166574	0.0843888790299437
GO:1990380	K48-linked deubiquitinase activity	5/1388	19/18639	0.263157894736842	3.53386167146974	0.0109473545820631	0.0843888790299437
GO:0001786	phosphatidylserine binding	10/1388	59/18639	0.169491525423729	2.27604650026865	0.0111611370163261	0.0854708124144973
GO:0002020	protease binding	18/1388	136/18639	0.132352941176471	1.77732454653331	0.0122167704924726	0.0917440055047617
GO:0019838	growth factor binding	18/1388	136/18639	0.132352941176471	1.77732454653331	0.0122167704924726	0.0917440055047617
GO:0044325	transmembrane transporter binding	18/1388	136/18639	0.132352941176471	1.77732454653331	0.0122167704924726	0.0917440055047617
GO:0005085	guanyl-nucleotide exchange factor activity	27/1388	230/18639	0.117391304347826	1.57640959779476	0.0125452336437337	0.0936067433417055
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/1388	13/18639	0.307692307692308	4.1318998004877	0.0126956076844493	0.0941253970999933
GO:0008320	protein transmembrane transporter activity	6/1388	27/18639	0.222222222222222	2.98414985590778	0.0128500113462135	0.0945531637083951
GO:0048156	tau protein binding	8/1388	43/18639	0.186046511627907	2.49835801889954	0.0129157672075901	0.0945531637083951
GO:0016922	nuclear receptor binding	18/1388	137/18639	0.131386861313869	1.76435137466081	0.0131172227574903	0.0954277955607417
GO:0004725	protein tyrosine phosphatase activity	14/1388	98/18639	0.142857142857143	1.91838205022643	0.0136153955537325	0.0984367728232585
GO:0005496	steroid binding	15/1388	108/18639	0.138888888888889	1.86509365994236	0.0139397768913516	0.100159878404526
GO:0046966	nuclear thyroid hormone receptor binding	6/1388	28/18639	0.214285714285714	2.87757307533965	0.0153489015592712	0.108279523727223
GO:0051019	mitogen-activated protein kinase binding	6/1388	28/18639	0.214285714285714	2.87757307533965	0.0153489015592712	0.108279523727223
GO:0051537	2 iron, 2 sulfur cluster binding	6/1388	28/18639	0.214285714285714	2.87757307533965	0.0153489015592712	0.108279523727223
GO:0019210	kinase inhibitor activity	13/1388	90/18639	0.144444444444444	1.93969740634006	0.0156352130121136	0.109634867145182
GO:0001217	DNA-binding transcription repressor activity	31/1388	278/18639	0.111510791366906	1.49744210395372	0.0157993316605203	0.11012228774159
GO:0030971	receptor tyrosine kinase binding	12/1388	81/18639	0.148148148148148	1.98943323727185	0.0163850900795249	0.113310143119943
GO:0005178	integrin binding	20/1388	161/18639	0.124223602484472	1.66815830454472	0.0165723976589804	0.113310143119943
GO:0008191	metalloendopeptidase inhibitor activity	4/1388	14/18639	0.285714285714286	3.83676410045286	0.0167437796680922	0.113310143119943
GO:0044548	S100 protein binding	4/1388	14/18639	0.285714285714286	3.83676410045286	0.0167437796680922	0.113310143119943
GO:0061665	SUMO ligase activity	4/1388	14/18639	0.285714285714286	3.83676410045286	0.0167437796680922	0.113310143119943
GO:0008009	chemokine activity	8/1388	45/18639	0.177777777777778	2.38731988472622	0.0168407686939434	0.113310143119943
GO:0042379	chemokine receptor binding	11/1388	72/18639	0.152777777777778	2.0516030259366	0.0169937336987311	0.113682218536339
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	9/1388	54/18639	0.166666666666667	2.23811239193084	0.0173844011936287	0.115631102796479
GO:0030291	protein serine/threonine kinase inhibitor activity	8/1388	46/18639	0.173913043478261	2.33542162636261	0.019095666341053	0.126291793301055
GO:0015078	proton transmembrane transporter activity	22/1388	185/18639	0.118918918918919	1.5969234364047	0.0197598383178008	0.12994605537808
GO:0031683	G-protein beta/gamma-subunit complex binding	5/1388	22/18639	0.227272727272727	3.05197144354205	0.0205939345706254	0.134670448540494
GO:0001965	G-protein alpha-subunit binding	6/1388	30/18639	0.2	2.685734870317	0.0213153642454848	0.136094018011952
GO:0031210	phosphatidylcholine binding	6/1388	30/18639	0.2	2.685734870317	0.0213153642454848	0.136094018011952
GO:0000774	adenyl-nucleotide exchange factor activity	4/1388	15/18639	0.266666666666667	3.58097982708934	0.021513143740721	0.136094018011952
GO:0015929	hexosaminidase activity	4/1388	15/18639	0.266666666666667	3.58097982708934	0.021513143740721	0.136094018011952
GO:0050780	dopamine receptor binding	4/1388	15/18639	0.266666666666667	3.58097982708934	0.021513143740721	0.136094018011952
GO:0061578	K63-linked deubiquitinase activity	4/1388	15/18639	0.266666666666667	3.58097982708934	0.021513143740721	0.136094018011952
GO:0003712	transcription coregulator activity	49/1388	495/18639	0.098989898989899	1.32930311763165	0.0251412747860258	0.157340790143398
GO:0015085	calcium ion transmembrane transporter activity	18/1388	147/18639	0.122448979591837	1.64432747162265	0.0252670243008522	0.157340790143398
GO:0009055	electron transfer activity	15/1388	116/18639	0.129310344827586	1.73646651098082	0.0252772575230374	0.157340790143398
GO:0005159	insulin-like growth factor receptor binding	4/1388	16/18639	0.25	3.35716858789625	0.027031818341513	0.166262995757213
GO:0055102	lipase inhibitor activity	4/1388	16/18639	0.25	3.35716858789625	0.027031818341513	0.166262995757213
GO:0016763	pentosyltransferase activity	8/1388	49/18639	0.163265306122449	2.19243662883021	0.027139148791985	0.166262995757213
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	29/1388	268/18639	0.108208955223881	1.45310282162674	0.0273013708541584	0.166381129184504
GO:0030295	protein kinase activator activity	17/1388	139/18639	0.122302158273381	1.64235585594925	0.0293845542138001	0.173593397435382
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/1388	24/18639	0.208333333333333	2.79764048991354	0.029393644432764	0.173593397435382
GO:0004622	lysophospholipase activity	5/1388	24/18639	0.208333333333333	2.79764048991354	0.029393644432764	0.173593397435382
GO:0035035	histone acetyltransferase binding	5/1388	24/18639	0.208333333333333	2.79764048991354	0.029393644432764	0.173593397435382
GO:0050431	transforming growth factor beta binding	5/1388	24/18639	0.208333333333333	2.79764048991354	0.029393644432764	0.173593397435382
GO:0050699	WW domain binding	5/1388	24/18639	0.208333333333333	2.79764048991354	0.029393644432764	0.173593397435382
GO:0004197	cysteine-type endopeptidase activity	12/1388	88/18639	0.136363636363636	1.83118286612523	0.029640164174084	0.173593397435382
GO:0001530	lipopolysaccharide binding	7/1388	41/18639	0.170731707317073	2.2927004990511	0.0301853493771125	0.173593397435382
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/1388	41/18639	0.170731707317073	2.2927004990511	0.0301853493771125	0.173593397435382
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/1388	41/18639	0.170731707317073	2.2927004990511	0.0301853493771125	0.173593397435382
GO:0042169	SH2 domain binding	7/1388	41/18639	0.170731707317073	2.2927004990511	0.0301853493771125	0.173593397435382
GO:0032813	tumor necrosis factor receptor superfamily binding	8/1388	50/18639	0.16	2.1485878962536	0.0302744498963767	0.173593397435382
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	12/1388	89/18639	0.134831460674157	1.8106077777418	0.0320274339117598	0.176289166129971
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	12/1388	89/18639	0.134831460674157	1.8106077777418	0.0320274339117598	0.176289166129971
GO:0016798	hydrolase activity, acting on glycosyl bonds	16/1388	130/18639	0.123076923076923	1.65275992019508	0.0321686713543078	0.176289166129971
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0005131	growth hormone receptor binding	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0005522	profilin binding	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0008140	cAMP response element binding protein binding	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0008239	dipeptidyl-peptidase activity	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0042975	peroxisome proliferator activated receptor binding	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0070513	death domain binding	3/1388	10/18639	0.3	4.0286023054755	0.0332657596223328	0.176289166129971
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/1388	17/18639	0.235294117647059	3.15968808272589	0.0333192582032591	0.176289166129971
GO:0008484	sulfuric ester hydrolase activity	4/1388	17/18639	0.235294117647059	3.15968808272589	0.0333192582032591	0.176289166129971
GO:0016805	dipeptidase activity	4/1388	17/18639	0.235294117647059	3.15968808272589	0.0333192582032591	0.176289166129971
GO:0046965	nuclear retinoid X receptor binding	4/1388	17/18639	0.235294117647059	3.15968808272589	0.0333192582032591	0.176289166129971
GO:0051787	misfolded protein binding	4/1388	17/18639	0.235294117647059	3.15968808272589	0.0333192582032591	0.176289166129971
GO:0042056	chemoattractant activity	7/1388	42/18639	0.166666666666667	2.23811239193084	0.0339771582486058	0.177210819506491
GO:0048487	beta-tubulin binding	7/1388	42/18639	0.166666666666667	2.23811239193084	0.0339771582486058	0.177210819506491
GO:0140793	histone H2AXY142 phosphatase activity	12/1388	90/18639	0.133333333333333	1.79048991354467	0.034549314050167	0.177210819506491
GO:0015662	P-type ion transporter activity	5/1388	25/18639	0.2	2.685734870317	0.0345591546632075	0.177210819506491
GO:0042974	nuclear retinoic acid receptor binding	5/1388	25/18639	0.2	2.685734870317	0.0345591546632075	0.177210819506491
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	5/1388	25/18639	0.2	2.685734870317	0.0345591546632075	0.177210819506491
GO:0140358	P-type transmembrane transporter activity	5/1388	25/18639	0.2	2.685734870317	0.0345591546632075	0.177210819506491
GO:1902936	phosphatidylinositol bisphosphate binding	14/1388	111/18639	0.126126126126126	1.69370667497469	0.0360823226236401	0.184209752341742
GO:0030159	signaling receptor complex adaptor activity	8/1388	52/18639	0.153846153846154	2.06594990024385	0.0372710611173618	0.189447664369472
GO:0019903	protein phosphatase binding	17/1388	144/18639	0.118055555555556	1.58532961095101	0.0393905150395253	0.19835437563688
GO:0046982	protein heterodimerization activity	37/1388	369/18639	0.100271002710027	1.34650664229985	0.0396979913793588	0.19835437563688
GO:0008198	ferrous iron binding	5/1388	26/18639	0.192307692307692	2.58243737530481	0.0402516765988711	0.19835437563688
GO:0019865	immunoglobulin binding	5/1388	26/18639	0.192307692307692	2.58243737530481	0.0402516765988711	0.19835437563688
GO:0043548	phosphatidylinositol 3-kinase binding	5/1388	26/18639	0.192307692307692	2.58243737530481	0.0402516765988711	0.19835437563688
GO:0070412	R-SMAD binding	5/1388	26/18639	0.192307692307692	2.58243737530481	0.0402516765988711	0.19835437563688
GO:0008525	phosphatidylcholine transporter activity	4/1388	18/18639	0.222222222222222	2.98414985590778	0.0403865867920452	0.19835437563688
GO:1990381	ubiquitin-specific protease binding	4/1388	18/18639	0.222222222222222	2.98414985590778	0.0403865867920452	0.19835437563688
GO:0046943	carboxylic acid transmembrane transporter activity	21/1388	188/18639	0.111702127659574	1.5000114967196	0.0406310964168237	0.198716790878919
GO:0061631	ubiquitin conjugating enzyme activity	6/1388	35/18639	0.171428571428571	2.30205846027172	0.0425573894876664	0.203057394550968
GO:0005342	organic acid transmembrane transporter activity	21/1388	189/18639	0.111111111111111	1.49207492795389	0.0426366125260906	0.203057394550968
GO:0001851	complement component C3b binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0008199	ferric iron binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0008432	JUN kinase binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0032050	clathrin heavy chain binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0032794	GTPase activating protein binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0034713	type I transforming growth factor beta receptor binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0048185	activin binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0140031	phosphorylation-dependent protein binding	3/1388	11/18639	0.272727272727273	3.66236573225046	0.0432630874988318	0.203057394550968
GO:0030246	carbohydrate binding	29/1388	280/18639	0.103571428571429	1.39082698641416	0.0445947375068139	0.208466965694503
GO:0004364	glutathione transferase activity	5/1388	27/18639	0.185185185185185	2.48679154658982	0.0464793277926569	0.21640775020261
GO:0051117	ATPase binding	11/1388	84/18639	0.130952380952381	1.75851687937423	0.0467726513692686	0.216905841409676
GO:0015245	fatty acid transmembrane transporter activity	4/1388	19/18639	0.210526315789474	2.82708933717579	0.048237048714707	0.222809225015551
GO:0042826	histone deacetylase binding	15/1388	127/18639	0.118110236220472	1.58606389979351	0.0505321469541241	0.232487822350199
GO:0030276	clathrin binding	7/1388	46/18639	0.152173913043478	2.04349392306729	0.0522456217280093	0.239424817682688
GO:0019789	SUMO transferase activity	5/1388	28/18639	0.178571428571429	2.39797756278304	0.0532468117564363	0.243056034841145
GO:0004300	enoyl-CoA hydratase activity	3/1388	12/18639	0.25	3.35716858789625	0.054573559013154	0.245264952476105
GO:0004859	phospholipase inhibitor activity	3/1388	12/18639	0.25	3.35716858789625	0.054573559013154	0.245264952476105
GO:0035497	cAMP response element binding	3/1388	12/18639	0.25	3.35716858789625	0.054573559013154	0.245264952476105
GO:0097677	STAT family protein binding	3/1388	12/18639	0.25	3.35716858789625	0.054573559013154	0.245264952476105
GO:0001614	purinergic nucleotide receptor activity	4/1388	20/18639	0.2	2.685734870317	0.0568665488230616	0.251683128631345
GO:0016004	phospholipase activator activity	4/1388	20/18639	0.2	2.685734870317	0.0568665488230616	0.251683128631345
GO:0016502	nucleotide receptor activity	4/1388	20/18639	0.2	2.685734870317	0.0568665488230616	0.251683128631345
GO:0016505	peptidase activator activity involved in apoptotic process	4/1388	20/18639	0.2	2.685734870317	0.0568665488230616	0.251683128631345
GO:0004601	peroxidase activity	8/1388	57/18639	0.140350877192982	1.88472622478386	0.0592676420023174	0.261316421555672
GO:0043531	ADP binding	6/1388	38/18639	0.157894736842105	2.12031700288184	0.0600394731538113	0.263720553777496
GO:0004721	phosphoprotein phosphatase activity	19/1388	175/18639	0.108571428571429	1.45797035817209	0.0625699596675499	0.273802379898602
GO:0038187	pattern recognition receptor activity	7/1388	48/18639	0.145833333333333	1.95834834293948	0.063314951541943	0.276024732564875
GO:0030145	manganese ion binding	9/1388	68/18639	0.132352941176471	1.77732454653331	0.0643155278486337	0.279340576178394
GO:0001846	opsonin binding	4/1388	21/18639	0.19047619047619	2.55784273363524	0.0662642503719217	0.284618403811501
GO:0051010	microtubule plus-end binding	4/1388	21/18639	0.19047619047619	2.55784273363524	0.0662642503719217	0.284618403811501
GO:0072542	protein phosphatase activator activity	4/1388	21/18639	0.19047619047619	2.55784273363524	0.0662642503719217	0.284618403811501
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/1388	39/18639	0.153846153846154	2.06594990024385	0.0666869487410357	0.285209501077719
GO:0005035	death receptor activity	3/1388	13/18639	0.230769230769231	3.09892485036577	0.0671369444117655	0.285209501077719
GO:0005172	vascular endothelial growth factor receptor binding	3/1388	13/18639	0.230769230769231	3.09892485036577	0.0671369444117655	0.285209501077719
GO:0001968	fibronectin binding	5/1388	30/18639	0.166666666666667	2.23811239193084	0.0684035219356022	0.287442958603036
GO:0031624	ubiquitin conjugating enzyme binding	5/1388	30/18639	0.166666666666667	2.23811239193084	0.0684035219356022	0.287442958603036
GO:0051721	protein phosphatase 2A binding	5/1388	30/18639	0.166666666666667	2.23811239193084	0.0684035219356022	0.287442958603036
GO:0008514	organic anion transmembrane transporter activity	27/1388	269/18639	0.100371747211896	1.34785950740816	0.0696269084617838	0.288744354063599
GO:0004879	nuclear receptor activity	8/1388	59/18639	0.135593220338983	1.82083720021492	0.0699535290772637	0.288744354063599
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/1388	59/18639	0.135593220338983	1.82083720021492	0.0699535290772637	0.288744354063599
GO:0031593	polyubiquitin modification-dependent protein binding	8/1388	59/18639	0.135593220338983	1.82083720021492	0.0699535290772637	0.288744354063599
GO:0070888	E-box binding	8/1388	59/18639	0.135593220338983	1.82083720021492	0.0699535290772637	0.288744354063599
GO:0005319	lipid transporter activity	19/1388	178/18639	0.106741573033708	1.43339782404559	0.0715591521129083	0.294328102683482
GO:0019902	phosphatase binding	20/1388	190/18639	0.105263157894737	1.4135446685879	0.0736951545575222	0.299093025074779
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6/1388	40/18639	0.15	2.01430115273775	0.0737454451859636	0.299093025074779
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	6/1388	40/18639	0.15	2.01430115273775	0.0737454451859636	0.299093025074779
GO:0050997	quaternary ammonium group binding	6/1388	40/18639	0.15	2.01430115273775	0.0737454451859636	0.299093025074779
GO:0072341	modified amino acid binding	11/1388	91/18639	0.120879120879121	1.6232463501916	0.074940698211843	0.302839110822749
GO:0001098	basal transcription machinery binding	8/1388	60/18639	0.133333333333333	1.79048991354467	0.0757097777056872	0.302839110822749
GO:0001099	basal RNA polymerase II transcription machinery binding	8/1388	60/18639	0.133333333333333	1.79048991354467	0.0757097777056872	0.302839110822749
GO:0098531	ligand-modulated transcription factor activity	8/1388	60/18639	0.133333333333333	1.79048991354467	0.0757097777056872	0.302839110822749
GO:0015171	amino acid transmembrane transporter activity	12/1388	102/18639	0.117647058823529	1.57984404136294	0.0763759984926523	0.303566470262294
GO:0140517	protein-RNA adaptor activity	4/1388	22/18639	0.181818181818182	2.44157715483364	0.0764132094388763	0.303566470262294
GO:0005164	tumor necrosis factor receptor binding	5/1388	31/18639	0.161290322580645	2.16591521799758	0.0767859485981556	0.304009674041677
GO:0008474	palmitoyl-(protein) hydrolase activity	3/1388	14/18639	0.214285714285714	2.87757307533965	0.0808805347964038	0.314409127834975
GO:0019763	immunoglobulin receptor activity	3/1388	14/18639	0.214285714285714	2.87757307533965	0.0808805347964038	0.314409127834975
GO:0019992	diacylglycerol binding	3/1388	14/18639	0.214285714285714	2.87757307533965	0.0808805347964038	0.314409127834975
GO:0034236	protein kinase A catalytic subunit binding	3/1388	14/18639	0.214285714285714	2.87757307533965	0.0808805347964038	0.314409127834975
GO:0098599	palmitoyl hydrolase activity	3/1388	14/18639	0.214285714285714	2.87757307533965	0.0808805347964038	0.314409127834975
GO:0140789	histone phosphatase activity	15/1388	136/18639	0.110294117647059	1.48110378877776	0.0813344811649335	0.314409127834975
GO:0015026	coreceptor activity	8/1388	61/18639	0.131147540983607	1.76113761988	0.0817422562593952	0.314409127834975
GO:0016836	hydro-lyase activity	8/1388	61/18639	0.131147540983607	1.76113761988	0.0817422562593952	0.314409127834975
GO:0003714	transcription corepressor activity	21/1388	204/18639	0.102941176470588	1.38236353619257	0.0818436131735373	0.314409127834975
GO:0016887	ATP hydrolysis activity	39/1388	417/18639	0.0935251798561151	1.25591918396119	0.0832479203380108	0.318751905504752
GO:0031369	translation initiation factor binding	5/1388	32/18639	0.15625	2.09823036743516	0.0856949130362644	0.327045504177743
GO:0005158	insulin receptor binding	4/1388	23/18639	0.173913043478261	2.33542162636261	0.0872910269831646	0.332048220288901
GO:0019894	kinesin binding	6/1388	42/18639	0.142857142857143	1.91838205022643	0.0890855121706268	0.337770476112735
GO:0008237	metallopeptidase activity	19/1388	184/18639	0.103260869565217	1.3866565906528	0.0920546382347021	0.347181485325039
GO:0005539	glycosaminoglycan binding	24/1388	242/18639	0.0991735537190083	1.33176935718199	0.0921641571868016	0.347181485325039
GO:0070851	growth factor receptor binding	15/1388	139/18639	0.107913669064748	1.44913751995522	0.0938239277429	0.34819016656318
GO:0019239	deaminase activity	5/1388	33/18639	0.151515151515152	2.03464762902803	0.0951198147848836	0.34819016656318
GO:0030296	protein tyrosine kinase activator activity	5/1388	33/18639	0.151515151515152	2.03464762902803	0.0951198147848836	0.34819016656318
GO:0071889	14-3-3 protein binding	5/1388	33/18639	0.151515151515152	2.03464762902803	0.0951198147848836	0.34819016656318
GO:0140416	transcription regulator inhibitor activity	5/1388	33/18639	0.151515151515152	2.03464762902803	0.0951198147848836	0.34819016656318
GO:0016846	carbon-sulfur lyase activity	3/1388	15/18639	0.2	2.685734870317	0.0957223825603244	0.34819016656318
GO:0031386	protein tag activity	3/1388	15/18639	0.2	2.685734870317	0.0957223825603244	0.34819016656318
GO:0047372	monoacylglycerol lipase activity	3/1388	15/18639	0.2	2.685734870317	0.0957223825603244	0.34819016656318
GO:0120283	protein serine/threonine kinase binding	3/1388	15/18639	0.2	2.685734870317	0.0957223825603244	0.34819016656318
GO:0140776	protein-containing complex destabilizing activity	3/1388	15/18639	0.2	2.685734870317	0.0957223825603244	0.34819016656318
GO:0141047	molecular tag activity	3/1388	15/18639	0.2	2.685734870317	0.0957223825603244	0.34819016656318
GO:0140296	general transcription initiation factor binding	7/1388	53/18639	0.132075471698113	1.77359849926595	0.0967595812904155	0.350866519071787
GO:0015295	solute:proton symporter activity	4/1388	24/18639	0.166666666666667	2.23811239193084	0.0988705034932447	0.356301133331693
GO:0060229	lipase activator activity	4/1388	24/18639	0.166666666666667	2.23811239193084	0.0988705034932447	0.356301133331693
GO:0051287	NAD binding	7/1388	54/18639	0.12962962962963	1.74075408261287	0.104427112251199	0.373972377459523
GO:0140463	chromatin-protein adaptor activity	7/1388	54/18639	0.12962962962963	1.74075408261287	0.104427112251199	0.373972377459523
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	5/1388	34/18639	0.147058823529412	1.97480505170368	0.105047512807663	0.373972377459523
GO:0003774	cytoskeletal motor activity	16/1388	153/18639	0.104575163398693	1.40430581454484	0.105658323950214	0.373972377459523
GO:0016209	antioxidant activity	10/1388	86/18639	0.116279069767442	1.56147376181221	0.105683851918209	0.373972377459523
GO:0016790	thiolester hydrolase activity	6/1388	44/18639	0.136363636363636	1.83118286612523	0.106023096702442	0.373972377459523
GO:0043014	alpha-tubulin binding	6/1388	44/18639	0.136363636363636	1.83118286612523	0.106023096702442	0.373972377459523
GO:0017022	myosin binding	9/1388	76/18639	0.118421052631579	1.59023775216138	0.110906296687492	0.38537743509585
GO:0051536	iron-sulfur cluster binding	9/1388	76/18639	0.118421052631579	1.59023775216138	0.110906296687492	0.38537743509585
GO:0019211	phosphatase activator activity	4/1388	25/18639	0.16	2.1485878962536	0.111120284222776	0.38537743509585
GO:0047617	fatty acyl-CoA hydrolase activity	4/1388	25/18639	0.16	2.1485878962536	0.111120284222776	0.38537743509585
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1388	16/18639	0.1875	2.51787644092219	0.111574051226204	0.38537743509585
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/1388	16/18639	0.1875	2.51787644092219	0.111574051226204	0.38537743509585
GO:0070411	I-SMAD binding	3/1388	16/18639	0.1875	2.51787644092219	0.111574051226204	0.38537743509585
GO:0001216	DNA-binding transcription activator activity	44/1388	491/18639	0.0896130346232179	1.20338425961251	0.115190892336674	0.396455424283775
GO:0005154	epidermal growth factor receptor binding	5/1388	35/18639	0.142857142857143	1.91838205022643	0.115462533360996	0.396455424283775
GO:0051540	metal cluster binding	9/1388	77/18639	0.116883116883117	1.56958531382163	0.117782382224803	0.403231449734326
GO:0170055	lipid transmembrane transporter activity	7/1388	56/18639	0.125	1.67858429394813	0.120708834275382	0.412038366852036
GO:0050840	extracellular matrix binding	8/1388	67/18639	0.119402985074627	1.60342380317433	0.123661890535266	0.413825974677155
GO:0005160	transforming growth factor beta receptor binding	4/1388	26/18639	0.153846153846154	2.06594990024385	0.12400548560894	0.413825974677155
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/1388	26/18639	0.153846153846154	2.06594990024385	0.12400548560894	0.413825974677155
GO:0016289	acyl-CoA hydrolase activity	4/1388	26/18639	0.153846153846154	2.06594990024385	0.12400548560894	0.413825974677155
GO:0050681	nuclear androgen receptor binding	4/1388	26/18639	0.153846153846154	2.06594990024385	0.12400548560894	0.413825974677155
GO:1901681	sulfur compound binding	26/1388	275/18639	0.0945454545454545	1.26962012051349	0.124342209166292	0.413825974677155
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	6/1388	46/18639	0.130434782608696	1.75156621977196	0.124496693089117	0.413825974677155
GO:0004033	aldo-keto reductase (NADPH) activity	5/1388	36/18639	0.138888888888889	1.86509365994236	0.126347284842143	0.413825974677155
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/1388	36/18639	0.138888888888889	1.86509365994236	0.126347284842143	0.413825974677155
GO:0004659	prenyltransferase activity	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0015278	intracellularly gated calcium channel activity	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0038191	neuropilin binding	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0045236	CXCR chemokine receptor binding	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0070402	NADPH binding	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0070403	NAD+ binding	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0070492	oligosaccharide binding	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:1990226	histone methyltransferase binding	3/1388	17/18639	0.176470588235294	2.36976606204441	0.128342935445406	0.413825974677155
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	43/1388	484/18639	0.0888429752066116	1.19304338247553	0.129746642637985	0.417196386824901
GO:0141108	transporter regulator activity	17/1388	170/18639	0.1	1.3428674351585	0.131368468647996	0.420222583646048
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	22/1388	229/18639	0.0960698689956332	1.29009098574179	0.131409811380723	0.420222583646048
GO:0001784	phosphotyrosine residue binding	6/1388	47/18639	0.127659574468085	1.71429885339383	0.13428411523091	0.428237561996654
GO:0035255	ionotropic glutamate receptor binding	4/1388	27/18639	0.148148148148148	1.98943323727185	0.137488295663946	0.437257858341074
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	10/1388	91/18639	0.10989010989011	1.47567850017418	0.138790258381055	0.440195805873429
GO:0005516	calmodulin binding	20/1388	207/18639	0.0966183574879227	1.29745645909034	0.139261610051981	0.440490527447027
GO:0048306	calcium-dependent protein binding	9/1388	80/18639	0.1125	1.51072586455331	0.139759471721063	0.440867276648558
GO:0140693	molecular condensate scaffold activity	6/1388	48/18639	0.125	1.67858429394813	0.144422567186476	0.445604893286704
GO:0000900	mRNA regulatory element binding translation repressor activity	3/1388	18/18639	0.166666666666667	2.23811239193084	0.145934205176079	0.445604893286704
GO:0015172	acidic amino acid transmembrane transporter activity	3/1388	18/18639	0.166666666666667	2.23811239193084	0.145934205176079	0.445604893286704
GO:0032393	MHC class I receptor activity	3/1388	18/18639	0.166666666666667	2.23811239193084	0.145934205176079	0.445604893286704
GO:0035615	clathrin adaptor activity	3/1388	18/18639	0.166666666666667	2.23811239193084	0.145934205176079	0.445604893286704
GO:0050811	GABA receptor binding	3/1388	18/18639	0.166666666666667	2.23811239193084	0.145934205176079	0.445604893286704
GO:0070064	proline-rich region binding	3/1388	18/18639	0.166666666666667	2.23811239193084	0.145934205176079	0.445604893286704
GO:0070063	RNA polymerase binding	7/1388	59/18639	0.11864406779661	1.59323255018805	0.147398206496602	0.445604893286704
GO:0033192	calmodulin-dependent protein phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0140791	histone H2AXS140 phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:1990439	MAP kinase serine/threonine phosphatase activity	9/1388	81/18639	0.111111111111111	1.49207492795389	0.147521787749021	0.445604893286704
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/1388	70/18639	0.114285714285714	1.53470564018114	0.148152142355631	0.445604893286704
GO:0097110	scaffold protein binding	8/1388	70/18639	0.114285714285714	1.53470564018114	0.148152142355631	0.445604893286704
GO:0141052	histone H3 demethylase activity	4/1388	28/18639	0.142857142857143	1.91838205022643	0.151528542981864	0.454585628945592
GO:0019787	ubiquitin-like protein transferase activity	42/1388	479/18639	0.0876826722338205	1.17746205170474	0.152078479152548	0.455062595716108
GO:0001222	transcription corepressor binding	6/1388	49/18639	0.122448979591837	1.64432747162265	0.154898611165947	0.460549362000601
GO:0035254	glutamate receptor binding	6/1388	49/18639	0.122448979591837	1.64432747162265	0.154898611165947	0.460549362000601
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	9/1388	82/18639	0.109756097560976	1.47387889224714	0.15549475881979	0.460549362000601
GO:0033549	MAP kinase phosphatase activity	9/1388	82/18639	0.109756097560976	1.47387889224714	0.15549475881979	0.460549362000601
GO:0008234	cysteine-type peptidase activity	18/1388	187/18639	0.0962566844919786	1.29259967020604	0.157961683388017	0.466668526557491
GO:0016829	lyase activity	19/1388	200/18639	0.095	1.27572406340058	0.163485318555207	0.469064616492707
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	9/1388	83/18639	0.108433734939759	1.45612131523211	0.163673136294016	0.469064616492707
GO:0042834	peptidoglycan binding	3/1388	19/18639	0.157894736842105	2.12031700288184	0.164252422012586	0.469064616492707
GO:0043395	heparan sulfate proteoglycan binding	3/1388	19/18639	0.157894736842105	2.12031700288184	0.164252422012586	0.469064616492707
GO:0070003	threonine-type peptidase activity	3/1388	19/18639	0.157894736842105	2.12031700288184	0.164252422012586	0.469064616492707
GO:0005518	collagen binding	8/1388	72/18639	0.111111111111111	1.49207492795389	0.165689184365125	0.469064616492707
GO:0003785	actin monomer binding	4/1388	29/18639	0.137931034482759	1.85223094504621	0.166084230554336	0.469064616492707
GO:0043236	laminin binding	4/1388	29/18639	0.137931034482759	1.85223094504621	0.166084230554336	0.469064616492707
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/1388	29/18639	0.137931034482759	1.85223094504621	0.166084230554336	0.469064616492707
GO:0051861	glycolipid binding	4/1388	29/18639	0.137931034482759	1.85223094504621	0.166084230554336	0.469064616492707
GO:0099604	ligand-gated calcium channel activity	4/1388	29/18639	0.137931034482759	1.85223094504621	0.166084230554336	0.469064616492707
GO:0106222	lncRNA binding	4/1388	29/18639	0.137931034482759	1.85223094504621	0.166084230554336	0.469064616492707
GO:0001094	TFIID-class transcription factor complex binding	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0004090	carbonyl reductase (NADPH) activity	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0005031	tumor necrosis factor receptor activity	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0005345	purine nucleobase transmembrane transporter activity	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0008190	eukaryotic initiation factor 4E binding	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0035256	G protein-coupled glutamate receptor binding	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0043422	protein kinase B binding	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0050308	sugar-phosphatase activity	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0071723	lipopeptide binding	2/1388	10/18639	0.2	2.685734870317	0.167638213454438	0.469064616492707
GO:0017018	myosin phosphatase activity	9/1388	84/18639	0.107142857142857	1.43878653766982	0.172051263160155	0.480258202202448
GO:0015036	disulfide oxidoreductase activity	5/1388	40/18639	0.125	1.67858429394813	0.174169891662421	0.485008980610188
GO:0043539	protein serine/threonine kinase activator activity	8/1388	73/18639	0.10958904109589	1.47163554537918	0.174799528928012	0.485600600649658
GO:0016407	acetyltransferase activity	10/1388	96/18639	0.104166666666667	1.39882024495677	0.176668967806473	0.489625425063653
GO:0004386	helicase activity	15/1388	155/18639	0.0967741935483871	1.29954913079855	0.179339297208294	0.495845467815805
GO:0008106	alcohol dehydrogenase (NADP+) activity	4/1388	30/18639	0.133333333333333	1.79048991354467	0.181112031880295	0.498379208294712
GO:0032452	histone demethylase activity	4/1388	30/18639	0.133333333333333	1.79048991354467	0.181112031880295	0.498379208294712
GO:0000339	RNA cap binding	3/1388	20/18639	0.15	2.01430115273775	0.183202870222502	0.499410166133472
GO:0016408	C-acyltransferase activity	3/1388	20/18639	0.15	2.01430115273775	0.183202870222502	0.499410166133472
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/1388	20/18639	0.15	2.01430115273775	0.183202870222502	0.499410166133472
GO:0030742	GTP-dependent protein binding	3/1388	20/18639	0.15	2.01430115273775	0.183202870222502	0.499410166133472
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	13/1388	132/18639	0.0984848484848485	1.32252095886822	0.184024708360646	0.500478412457457
GO:0005507	copper ion binding	7/1388	63/18639	0.111111111111111	1.49207492795389	0.186848784181609	0.506974323513737
GO:0000099	sulfur amino acid transmembrane transporter activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0005114	type II transforming growth factor beta receptor binding	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0005225	volume-sensitive anion channel activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0008526	phosphatidylinositol transfer activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0015205	nucleobase transmembrane transporter activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0019107	myristoyltransferase activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0019203	carbohydrate phosphatase activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0045294	alpha-catenin binding	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0047676	arachidonate-CoA ligase activity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0050998	nitric-oxide synthase binding	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0097493	structural molecule activity conferring elasticity	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/1388	11/18639	0.181818181818182	2.44157715483364	0.195277130333462	0.515326258066028
GO:0005452	solute:inorganic anion antiporter activity	4/1388	31/18639	0.129032258064516	1.73273217439807	0.196567747922093	0.515326258066028
GO:0016411	acylglycerol O-acyltransferase activity	4/1388	31/18639	0.129032258064516	1.73273217439807	0.196567747922093	0.515326258066028
GO:0140457	protein demethylase activity	4/1388	31/18639	0.129032258064516	1.73273217439807	0.196567747922093	0.515326258066028
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	12/1388	122/18639	0.0983606557377049	1.32085321491	0.197187813032676	0.515790144651763
GO:1901505	carbohydrate derivative transmembrane transporter activity	6/1388	53/18639	0.113207547169811	1.5202272850851	0.19987733124492	0.521652945222168
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/1388	21/18639	0.142857142857143	1.91838205022643	0.202692640197599	0.525465998196002
GO:0005123	death receptor binding	3/1388	21/18639	0.142857142857143	1.91838205022643	0.202692640197599	0.525465998196002
GO:0140312	cargo adaptor activity	3/1388	21/18639	0.142857142857143	1.91838205022643	0.202692640197599	0.525465998196002
GO:0015297	antiporter activity	13/1388	135/18639	0.0962962962962963	1.2931316042267	0.205421050292267	0.531355783422664
GO:0016651	oxidoreductase activity, acting on NAD(P)H	9/1388	88/18639	0.102272727272727	1.37338714959392	0.20743509231754	0.535375714983628
GO:0008201	heparin binding	16/1388	172/18639	0.0930232558139535	1.24917900944977	0.211362737842521	0.540700376834905
GO:0005200	structural constituent of cytoskeleton	11/1388	112/18639	0.0982142857142857	1.31888765953067	0.211660096864758	0.540700376834905
GO:0016755	aminoacyltransferase activity	42/1388	496/18639	0.0846774193548387	1.13710548944873	0.211812201039801	0.540700376834905
GO:0099106	ion channel regulator activity	15/1388	160/18639	0.09375	1.2589382204611	0.212131758543796	0.540700376834905
GO:0043425	bHLH transcription factor binding	4/1388	32/18639	0.125	1.67858429394813	0.212406724334354	0.540700376834905
GO:0051059	NF-kappaB binding	4/1388	32/18639	0.125	1.67858429394813	0.212406724334354	0.540700376834905
GO:0008375	acetylglucosaminyltransferase activity	5/1388	43/18639	0.116279069767442	1.56147376181221	0.213871224401772	0.540700376834905
GO:0140030	modification-dependent protein binding	16/1388	173/18639	0.092485549132948	1.24195832153387	0.217959109832398	0.540700376834905
GO:0061659	ubiquitin-like protein ligase activity	32/1388	372/18639	0.0860215053763441	1.15515478293204	0.220797814721969	0.540700376834905
GO:0008093	cytoskeletal anchor activity	3/1388	22/18639	0.136363636363636	1.83118286612523	0.222631497685818	0.540700376834905
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/1388	22/18639	0.136363636363636	1.83118286612523	0.222631497685818	0.540700376834905
GO:0033691	sialic acid binding	3/1388	22/18639	0.136363636363636	1.83118286612523	0.222631497685818	0.540700376834905
GO:0000340	RNA 7-methylguanosine cap binding	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0004126	cytidine deaminase activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0005025	transforming growth factor beta receptor activity, type I	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0005026	transforming growth factor beta receptor activity, type II	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0005078	MAP-kinase scaffold activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0015368	calcium:monoatomic cation antiporter activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0016208	AMP binding	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0016361	activin receptor activity, type I	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0016362	activin receptor activity, type II	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0016801	hydrolase activity, acting on ether bonds	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0016803	ether hydrolase activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0016840	carbon-nitrogen lyase activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0017002	activin receptor activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0042301	phosphate ion binding	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0070410	co-SMAD binding	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:1990459	transferrin receptor binding	2/1388	12/18639	0.166666666666667	2.23811239193084	0.223417844597523	0.540700376834905
GO:0019199	transmembrane receptor protein kinase activity	8/1388	78/18639	0.102564102564103	1.3772999334959	0.22343374678487	0.540700376834905
GO:0008374	O-acyltransferase activity	6/1388	55/18639	0.109090909090909	1.46494629290018	0.223979608154755	0.540896813054222
GO:0016791	phosphatase activity	24/1388	273/18639	0.0879120879120879	1.18054280013934	0.226258778406089	0.545269602618401
GO:0001046	core promoter sequence-specific DNA binding	5/1388	44/18639	0.113636363636364	1.52598572177102	0.227697907440148	0.547604058389116
GO:0019956	chemokine binding	4/1388	33/18639	0.121212121212121	1.62771810322243	0.228584229099799	0.548602149839517
GO:0016835	carbon-oxygen lyase activity	8/1388	79/18639	0.10126582278481	1.35986575712253	0.233712182479457	0.559755103716229
GO:0140597	protein carrier chaperone	17/1388	188/18639	0.0904255319148936	1.21429502115396	0.236294082192648	0.563709508509984
GO:0004722	protein serine/threonine phosphatase activity	10/1388	103/18639	0.0970873786407767	1.30375479141602	0.236668453648388	0.563709508509984
GO:0001221	transcription coregulator binding	11/1388	115/18639	0.0956521739130435	1.28448189449944	0.236816107956514	0.563709508509984
GO:1990841	promoter-specific chromatin binding	7/1388	68/18639	0.102941176470588	1.38236353619257	0.241379047681082	0.571259615133284
GO:0051539	4 iron, 4 sulfur cluster binding	5/1388	45/18639	0.111111111111111	1.49207492795389	0.241776065832305	0.571259615133284
GO:0017134	fibroblast growth factor binding	3/1388	23/18639	0.130434782608696	1.75156621977196	0.242932568291216	0.571259615133284
GO:0042171	lysophosphatidic acid acyltransferase activity	3/1388	23/18639	0.130434782608696	1.75156621977196	0.242932568291216	0.571259615133284
GO:0043274	phospholipase binding	3/1388	23/18639	0.130434782608696	1.75156621977196	0.242932568291216	0.571259615133284
GO:0071617	lysophospholipid acyltransferase activity	3/1388	23/18639	0.130434782608696	1.75156621977196	0.242932568291216	0.571259615133284
GO:0030332	cyclin binding	4/1388	34/18639	0.117647058823529	1.57984404136294	0.245055791272083	0.574907976622358
GO:0052689	carboxylic ester hydrolase activity	9/1388	92/18639	0.0978260869565217	1.31367466482897	0.245471876616247	0.574907976622358
GO:0019855	calcium channel inhibitor activity	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0035673	oligopeptide transmembrane transporter activity	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0043560	insulin receptor substrate binding	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0051011	microtubule minus-end binding	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0070123	transforming growth factor beta receptor activity, type III	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0071714	icosanoid transmembrane transporter activity	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0071837	HMG box domain binding	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/1388	13/18639	0.153846153846154	2.06594990024385	0.251832553722207	0.578171780143291
GO:0002039	p53 binding	7/1388	69/18639	0.101449275362319	1.36232928204486	0.252854407699921	0.579375060162812
GO:0019208	phosphatase regulator activity	11/1388	117/18639	0.094017094017094	1.26252493903791	0.254183769915229	0.581276833362135
GO:0016298	lipase activity	12/1388	130/18639	0.0923076923076923	1.23956994014631	0.261260147912826	0.59328621438565
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	12/1388	130/18639	0.0923076923076923	1.23956994014631	0.261260147912826	0.59328621438565
GO:0016757	glycosyltransferase activity	23/1388	267/18639	0.0861423220973783	1.15677719133504	0.262828426568932	0.59328621438565
GO:0005315	phosphate transmembrane transporter activity	3/1388	24/18639	0.125	1.67858429394813	0.263512863262355	0.59328621438565
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/1388	24/18639	0.125	1.67858429394813	0.263512863262355	0.59328621438565
GO:0030215	semaphorin receptor binding	3/1388	24/18639	0.125	1.67858429394813	0.263512863262355	0.59328621438565
GO:0030552	cAMP binding	3/1388	24/18639	0.125	1.67858429394813	0.263512863262355	0.59328621438565
GO:0070300	phosphatidic acid binding	3/1388	24/18639	0.125	1.67858429394813	0.263512863262355	0.59328621438565
GO:0008013	beta-catenin binding	10/1388	106/18639	0.0943396226415094	1.26685607090425	0.264437275577822	0.594218125043601
GO:0016247	channel regulator activity	15/1388	168/18639	0.0892857142857143	1.19898878139152	0.269526636648072	0.60105439422857
GO:0005262	calcium channel activity	12/1388	131/18639	0.0916030534351145	1.23010757419099	0.269742847998663	0.60105439422857
GO:0043495	protein-membrane adaptor activity	5/1388	47/18639	0.106382978723404	1.42858237782819	0.270577751353755	0.60105439422857
GO:0061749	forked DNA-dependent helicase activity	5/1388	47/18639	0.106382978723404	1.42858237782819	0.270577751353755	0.60105439422857
GO:0140359	ABC-type transporter activity	5/1388	47/18639	0.106382978723404	1.42858237782819	0.270577751353755	0.60105439422857
GO:1990518	single-stranded 3'-5' DNA helicase activity	5/1388	47/18639	0.106382978723404	1.42858237782819	0.270577751353755	0.60105439422857
GO:0045309	protein phosphorylated amino acid binding	6/1388	59/18639	0.101694915254237	1.36562790016119	0.274692489441014	0.608764522769131
GO:0004867	serine-type endopeptidase inhibitor activity	9/1388	95/18639	0.0947368421052632	1.27219020172911	0.275437437147589	0.608764522769131
GO:0030165	PDZ domain binding	8/1388	83/18639	0.0963855421686747	1.2943300579841	0.276328587111466	0.608764522769131
GO:0004190	aspartic-type endopeptidase activity	4/1388	36/18639	0.111111111111111	1.49207492795389	0.278706279111306	0.608764522769131
GO:0016409	palmitoyltransferase activity	4/1388	36/18639	0.111111111111111	1.49207492795389	0.278706279111306	0.608764522769131
GO:0004065	arylsulfatase activity	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0005313	L-glutamate transmembrane transporter activity	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0008494	translation activator activity	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0016530	metallochaperone activity	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0031404	chloride ion binding	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0098821	BMP receptor activity	2/1388	14/18639	0.142857142857143	1.91838205022643	0.280324556876507	0.608764522769131
GO:0001848	complement binding	3/1388	25/18639	0.12	1.6114409221902	0.284293669495025	0.609224697359151
GO:0003707	nuclear steroid receptor activity	3/1388	25/18639	0.12	1.6114409221902	0.284293669495025	0.609224697359151
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/1388	25/18639	0.12	1.6114409221902	0.284293669495025	0.609224697359151
GO:0017025	TBP-class protein binding	3/1388	25/18639	0.12	1.6114409221902	0.284293669495025	0.609224697359151
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/1388	25/18639	0.12	1.6114409221902	0.284293669495025	0.609224697359151
GO:0019707	protein-cysteine S-acyltransferase activity	3/1388	25/18639	0.12	1.6114409221902	0.284293669495025	0.609224697359151
GO:0009378	four-way junction helicase activity	5/1388	48/18639	0.104166666666667	1.39882024495677	0.285246958815066	0.609224697359151
GO:0036121	double-stranded DNA helicase activity	5/1388	48/18639	0.104166666666667	1.39882024495677	0.285246958815066	0.609224697359151
GO:0043138	3'-5' DNA helicase activity	5/1388	48/18639	0.104166666666667	1.39882024495677	0.285246958815066	0.609224697359151
GO:0004714	transmembrane receptor protein tyrosine kinase activity	6/1388	60/18639	0.1	1.3428674351585	0.287784267207298	0.612396502795785
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/1388	60/18639	0.1	1.3428674351585	0.287784267207298	0.612396502795785
GO:0005125	cytokine activity	20/1388	234/18639	0.0854700854700855	1.14774994457992	0.292867753011363	0.622076760046033
GO:0070001	aspartic-type peptidase activity	4/1388	37/18639	0.108108108108108	1.45174857854973	0.295800097621001	0.627160862715564
GO:0001637	G protein-coupled chemoattractant receptor activity	3/1388	26/18639	0.115384615384615	1.54946242518289	0.305200823914949	0.641252272629965
GO:0004950	chemokine receptor activity	3/1388	26/18639	0.115384615384615	1.54946242518289	0.305200823914949	0.641252272629965
GO:0030247	polysaccharide binding	3/1388	26/18639	0.115384615384615	1.54946242518289	0.305200823914949	0.641252272629965
GO:0030507	spectrin binding	3/1388	26/18639	0.115384615384615	1.54946242518289	0.305200823914949	0.641252272629965
GO:0052742	phosphatidylinositol kinase activity	3/1388	26/18639	0.115384615384615	1.54946242518289	0.305200823914949	0.641252272629965
GO:0140104	molecular carrier activity	21/1388	249/18639	0.0843373493975904	1.13253880073609	0.307998633227754	0.641706738525189
GO:0004129	cytochrome-c oxidase activity	2/1388	15/18639	0.133333333333333	1.79048991354467	0.308724891386689	0.641706738525189
GO:0004467	long-chain fatty acid-CoA ligase activity	2/1388	15/18639	0.133333333333333	1.79048991354467	0.308724891386689	0.641706738525189
GO:0005523	tropomyosin binding	2/1388	15/18639	0.133333333333333	1.79048991354467	0.308724891386689	0.641706738525189
GO:0042809	nuclear vitamin D receptor binding	2/1388	15/18639	0.133333333333333	1.79048991354467	0.308724891386689	0.641706738525189
GO:0045504	dynein heavy chain binding	2/1388	15/18639	0.133333333333333	1.79048991354467	0.308724891386689	0.641706738525189
GO:0048029	monosaccharide binding	7/1388	74/18639	0.0945945945945946	1.27028000623101	0.312325640706817	0.647163711761985
GO:0000146	microfilament motor activity	4/1388	38/18639	0.105263157894737	1.4135446685879	0.31301818704639	0.647163711761985
GO:0042887	amide transmembrane transporter activity	4/1388	38/18639	0.105263157894737	1.4135446685879	0.31301818704639	0.647163711761985
GO:0048020	CCR chemokine receptor binding	5/1388	50/18639	0.1	1.3428674351585	0.314988321759708	0.650082281078546
GO:0004175	endopeptidase activity	33/1388	405/18639	0.0814814814814815	1.09418828049952	0.319697990890743	0.658634444950132
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/1388	27/18639	0.111111111111111	1.49207492795389	0.326164889946324	0.668408330805496
GO:0005385	zinc ion transmembrane transporter activity	3/1388	27/18639	0.111111111111111	1.49207492795389	0.326164889946324	0.668408330805496
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/1388	27/18639	0.111111111111111	1.49207492795389	0.326164889946324	0.668408330805496
GO:1901682	sulfur compound transmembrane transporter activity	6/1388	63/18639	0.0952380952380952	1.27892136681762	0.327751887980953	0.670480136396889
GO:0005021	vascular endothelial growth factor receptor activity	5/1388	51/18639	0.0980392156862745	1.31653670113579	0.330008263809764	0.672731381916927
GO:0005048	signal sequence binding	5/1388	51/18639	0.0980392156862745	1.31653670113579	0.330008263809764	0.672731381916927
GO:0005024	transforming growth factor beta receptor activity	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0015923	mannosidase activity	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0016722	oxidoreductase activity, acting on metal ions	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0022858	alanine transmembrane transporter activity	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0140328	floppase activity	2/1388	16/18639	0.125	1.67858429394813	0.336889297123901	0.678441421889656
GO:0046906	tetrapyrrole binding	13/1388	152/18639	0.0855263157894737	1.14850504322767	0.343240910914775	0.690038722460791
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	5/1388	52/18639	0.0961538461538462	1.29121868765241	0.345093863821132	0.692567685323789
GO:0004842	ubiquitin-protein transferase activity	36/1388	449/18639	0.0801781737193764	1.07668658498232	0.345842355193729	0.692875217634252
GO:0046875	ephrin receptor binding	3/1388	28/18639	0.107142857142857	1.43878653766982	0.34712125158206	0.692961377081663
GO:0050698	proteoglycan sulfotransferase activity	3/1388	28/18639	0.107142857142857	1.43878653766982	0.34712125158206	0.692961377081663
GO:0032451	demethylase activity	4/1388	40/18639	0.1	1.3428674351585	0.347671343827913	0.692961377081663
GO:0003724	RNA helicase activity	7/1388	77/18639	0.0909090909090909	1.22078857741682	0.349180986706073	0.694780629958751
GO:0061775	cohesin loader activity	13/1388	153/18639	0.0849673202614379	1.14099847431768	0.351955607065895	0.699106359427819
GO:0160215	deacylase activity	6/1388	65/18639	0.0923076923076923	1.23956994014631	0.354789903694931	0.703535686372912
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/1388	128/18639	0.0859375	1.15402670208934	0.356017506984452	0.704769350561057
GO:0051018	protein kinase A binding	5/1388	53/18639	0.0943396226415094	1.26685607090425	0.360220585964488	0.710531501535402
GO:0016853	isomerase activity	15/1388	180/18639	0.0833333333333333	1.11905619596542	0.363814182404552	0.710531501535402
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/1388	17/18639	0.117647058823529	1.57984404136294	0.364695478681034	0.710531501535402
GO:0019198	transmembrane receptor protein phosphatase activity	2/1388	17/18639	0.117647058823529	1.57984404136294	0.364695478681034	0.710531501535402
GO:0031489	myosin V binding	2/1388	17/18639	0.117647058823529	1.57984404136294	0.364695478681034	0.710531501535402
GO:0032977	membrane insertase activity	2/1388	17/18639	0.117647058823529	1.57984404136294	0.364695478681034	0.710531501535402
GO:0045125	bioactive lipid receptor activity	2/1388	17/18639	0.117647058823529	1.57984404136294	0.364695478681034	0.710531501535402
GO:0001727	lipid kinase activity	4/1388	41/18639	0.0975609756097561	1.31011457088634	0.365032506802552	0.710531501535402
GO:0017080	sodium channel regulator activity	4/1388	41/18639	0.0975609756097561	1.31011457088634	0.365032506802552	0.710531501535402
GO:0140828	metal cation:monoatomic cation antiporter activity	4/1388	41/18639	0.0975609756097561	1.31011457088634	0.365032506802552	0.710531501535402
GO:0020037	heme binding	12/1388	142/18639	0.0845070422535211	1.13481755083817	0.367781555728967	0.71156777634221
GO:0004181	metallocarboxypeptidase activity	3/1388	29/18639	0.103448275862069	1.38917320878466	0.36801013862372	0.71156777634221
GO:0016417	S-acyltransferase activity	3/1388	29/18639	0.103448275862069	1.38917320878466	0.36801013862372	0.71156777634221
GO:0035250	UDP-galactosyltransferase activity	3/1388	29/18639	0.103448275862069	1.38917320878466	0.36801013862372	0.71156777634221
GO:0042578	phosphoric ester hydrolase activity	29/1388	363/18639	0.0798898071625344	1.0728142043966	0.373941482912209	0.719582990228512
GO:0008186	ATP-dependent activity, acting on RNA	7/1388	79/18639	0.0886075949367089	1.18988253748222	0.374010059354167	0.719582990228512
GO:0033293	monocarboxylic acid binding	7/1388	79/18639	0.0886075949367089	1.18988253748222	0.374010059354167	0.719582990228512
GO:0004520	DNA endonuclease activity	4/1388	42/18639	0.0952380952380952	1.27892136681762	0.38237033237132	0.733243932257359
GO:0043175	RNA polymerase core enzyme binding	4/1388	42/18639	0.0952380952380952	1.27892136681762	0.38237033237132	0.733243932257359
GO:0015291	secondary active transmembrane transporter activity	23/1388	287/18639	0.0801393728222996	1.07616554037092	0.387987586997656	0.73483945648904
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/1388	30/18639	0.1	1.3428674351585	0.388776594928546	0.73483945648904
GO:0016769	transferase activity, transferring nitrogenous groups	3/1388	30/18639	0.1	1.3428674351585	0.388776594928546	0.73483945648904
GO:0035925	mRNA 3'-UTR AU-rich region binding	3/1388	30/18639	0.1	1.3428674351585	0.388776594928546	0.73483945648904
GO:0051213	dioxygenase activity	8/1388	93/18639	0.0860215053763441	1.15515478293204	0.389612691506596	0.73483945648904
GO:0051219	phosphoprotein binding	8/1388	93/18639	0.0860215053763441	1.15515478293204	0.389612691506596	0.73483945648904
GO:0098632	cell-cell adhesion mediator activity	5/1388	55/18639	0.0909090909090909	1.22078857741682	0.390503170998511	0.73483945648904
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:0004706	JUN kinase kinase kinase activity	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:0070628	proteasome binding	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:0098641	cadherin binding involved in cell-cell adhesion	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:1901611	phosphatidylglycerol binding	2/1388	18/18639	0.111111111111111	1.49207492795389	0.392040637869153	0.73483945648904
GO:0008194	UDP-glycosyltransferase activity	12/1388	145/18639	0.0827586206896552	1.11133856702773	0.395463131002668	0.73909760970929
GO:0005548	phospholipid transporter activity	6/1388	68/18639	0.0882352941176471	1.18488303102221	0.395582311725848	0.73909760970929
GO:0042562	hormone binding	8/1388	94/18639	0.0851063829787234	1.14286590226255	0.401173992900107	0.748343794448277
GO:0019888	protein phosphatase regulator activity	9/1388	107/18639	0.0841121495327103	1.12951466508659	0.402698453728746	0.749985600224416
GO:0030170	pyridoxal phosphate binding	5/1388	56/18639	0.0892857142857143	1.19898878139152	0.405614060212063	0.754208891512526
GO:0004843	cysteine-type deubiquitinase activity	9/1388	108/18639	0.0833333333333333	1.11905619596542	0.413534520225191	0.766554856517657
GO:0001223	transcription coactivator binding	4/1388	44/18639	0.0909090909090909	1.22078857741682	0.416847730635361	0.766554856517657
GO:0030547	signaling receptor inhibitor activity	4/1388	44/18639	0.0909090909090909	1.22078857741682	0.416847730635361	0.766554856517657
GO:0003756	protein disulfide isomerase activity	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0005520	insulin-like growth factor binding	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0030506	ankyrin binding	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0046624	sphingolipid transporter activity	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0097001	ceramide binding	2/1388	19/18639	0.105263157894737	1.4135446685879	0.418839251499338	0.766554856517657
GO:0070279	vitamin B6 binding	5/1388	57/18639	0.087719298245614	1.17795389048991	0.42067622257975	0.7684789661185
GO:0031406	carboxylic acid binding	15/1388	187/18639	0.0802139037433155	1.07716639183837	0.421210979710999	0.7684789661185
GO:0004620	phospholipase activity	9/1388	109/18639	0.0825688073394495	1.10878962536023	0.424366587007921	0.773024581028514
GO:0008378	galactosyltransferase activity	3/1388	32/18639	0.09375	1.2589382204611	0.429745952616392	0.779165558949346
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/1388	32/18639	0.09375	1.2589382204611	0.429745952616392	0.779165558949346
GO:0042910	xenobiotic transmembrane transporter activity	3/1388	32/18639	0.09375	1.2589382204611	0.429745952616392	0.779165558949346
GO:0016779	nucleotidyltransferase activity	11/1388	136/18639	0.0808823529411765	1.08614277843702	0.433510128638891	0.784304452664936
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/1388	45/18639	0.0888888888888889	1.19365994236311	0.433927893055171	0.784304452664936
GO:0017116	single-stranded DNA helicase activity	5/1388	58/18639	0.0862068965517241	1.15764434065388	0.43566951639627	0.786231499356989
GO:0043177	organic acid binding	15/1388	189/18639	0.0793650793650794	1.06576780568135	0.437701534971951	0.788675830816334
GO:0001972	retinoic acid binding	2/1388	20/18639	0.1	1.3428674351585	0.445021071641208	0.797556115068038
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	2/1388	20/18639	0.1	1.3428674351585	0.445021071641208	0.797556115068038
GO:0043024	ribosomal small subunit binding	2/1388	20/18639	0.1	1.3428674351585	0.445021071641208	0.797556115068038
GO:0003713	transcription coactivator activity	20/1388	256/18639	0.078125	1.04911518371758	0.445370682812908	0.797556115068038
GO:0140713	histone chaperone activity	13/1388	164/18639	0.0792682926829268	1.06446808884515	0.449316186480752	0.799177435313757
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/1388	33/18639	0.0909090909090909	1.22078857741682	0.449862124968051	0.799177435313757
GO:0015459	potassium channel regulator activity	5/1388	59/18639	0.0847457627118644	1.13802325013432	0.450574796669905	0.799177435313757
GO:0000510	H3-H4 histone complex chaperone activity	12/1388	151/18639	0.0794701986754967	1.06717941866901	0.451082109107507	0.799177435313757
GO:0140584	chromatin extrusion motor activity	12/1388	151/18639	0.0794701986754967	1.06717941866901	0.451082109107507	0.799177435313757
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	12/1388	151/18639	0.0794701986754967	1.06717941866901	0.451082109107507	0.799177435313757
GO:0140849	ATP-dependent H2AZ histone chaperone activity	12/1388	151/18639	0.0794701986754967	1.06717941866901	0.451082109107507	0.799177435313757
GO:0015616	DNA translocase activity	12/1388	152/18639	0.0789473684210526	1.06015850144092	0.46032564038117	0.813078976333356
GO:0140674	ATP-dependent histone chaperone activity	12/1388	152/18639	0.0789473684210526	1.06015850144092	0.46032564038117	0.813078976333356
GO:0005504	fatty acid binding	4/1388	47/18639	0.0851063829787234	1.14286590226255	0.467636931354263	0.817456921352528
GO:0051427	hormone receptor binding	3/1388	34/18639	0.0882352941176471	1.18488303102221	0.46968209274508	0.817456921352528
GO:0090482	vitamin transmembrane transporter activity	3/1388	34/18639	0.0882352941176471	1.18488303102221	0.46968209274508	0.817456921352528
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0008373	sialyltransferase activity	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0015125	bile acid transmembrane transporter activity	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0019200	carbohydrate kinase activity	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0061891	calcium ion sensor activity	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0070182	DNA polymerase binding	2/1388	21/18639	0.0952380952380952	1.27892136681762	0.470529327582641	0.817456921352528
GO:0061630	ubiquitin protein ligase activity	27/1388	353/18639	0.0764872521246459	1.02712240082945	0.471476069939383	0.817880991668319
GO:0004713	protein tyrosine kinase activity	11/1388	140/18639	0.0785714285714286	1.05511012762454	0.472223248407001	0.817958126704983
GO:0003678	DNA helicase activity	6/1388	74/18639	0.0810810810810811	1.0888114339123	0.476417982098009	0.823997817477092
GO:0031490	chromatin DNA binding	10/1388	128/18639	0.078125	1.04911518371758	0.485182069877553	0.83791087438794
GO:0101005	deubiquitinase activity	9/1388	115/18639	0.0782608695652174	1.05093973186318	0.488840701407866	0.842304059798184
GO:0016229	steroid dehydrogenase activity	3/1388	35/18639	0.0857142857142857	1.15102923013586	0.489173148130217	0.842304059798184
GO:0008970	phospholipase A1 activity	2/1388	22/18639	0.0909090909090909	1.22078857741682	0.495319110572323	0.847869771626741
GO:0034062	5'-3' RNA polymerase activity	2/1388	22/18639	0.0909090909090909	1.22078857741682	0.495319110572323	0.847869771626741
GO:0097747	RNA polymerase activity	2/1388	22/18639	0.0909090909090909	1.22078857741682	0.495319110572323	0.847869771626741
GO:0140784	metal ion sensor activity	2/1388	22/18639	0.0909090909090909	1.22078857741682	0.495319110572323	0.847869771626741
GO:0015631	tubulin binding	29/1388	385/18639	0.0753246753246753	1.01151053557394	0.502612718079684	0.858017046511099
GO:0098631	cell adhesion mediator activity	6/1388	76/18639	0.0789473684210526	1.06015850144092	0.502721327938633	0.858017046511099
GO:0000993	RNA polymerase II complex binding	3/1388	36/18639	0.0833333333333333	1.11905619596542	0.508306499859209	0.860402855513268
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/1388	36/18639	0.0833333333333333	1.11905619596542	0.508306499859209	0.860402855513268
GO:0140658	ATP-dependent chromatin remodeler activity	12/1388	158/18639	0.0759493670886076	1.0198993178419	0.515194995305764	0.860402855513268
GO:0005283	amino acid:sodium symporter activity	2/1388	23/18639	0.0869565217391304	1.16771081318131	0.519355924122905	0.860402855513268
GO:0016849	phosphorus-oxygen lyase activity	2/1388	23/18639	0.0869565217391304	1.16771081318131	0.519355924122905	0.860402855513268
GO:0099186	structural constituent of postsynapse	2/1388	23/18639	0.0869565217391304	1.16771081318131	0.519355924122905	0.860402855513268
GO:0140103	catalytic activity, acting on a glycoprotein	2/1388	23/18639	0.0869565217391304	1.16771081318131	0.519355924122905	0.860402855513268
GO:0004536	DNA nuclease activity	5/1388	64/18639	0.078125	1.04911518371758	0.523182720655505	0.860402855513268
GO:0030551	cyclic nucleotide binding	3/1388	37/18639	0.0810810810810811	1.0888114339123	0.52705706476258	0.860402855513268
GO:0005010	insulin-like growth factor receptor activity	4/1388	51/18639	0.0784313725490196	1.05322936090863	0.532617463962449	0.860402855513268
GO:0016597	amino acid binding	4/1388	51/18639	0.0784313725490196	1.05322936090863	0.532617463962449	0.860402855513268
GO:0003689	DNA clamp loader activity	12/1388	160/18639	0.075	1.00715057636888	0.533154021967857	0.860402855513268
GO:0004382	GDP phosphatase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0004955	prostaglandin receptor activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0005337	nucleoside transmembrane transporter activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0015203	polyamine transmembrane transporter activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0015279	store-operated calcium channel activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0031419	cobalamin binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0032052	bile acid binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0043121	neurotrophin binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0043208	glycosphingolipid binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0043295	glutathione binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0045322	unmethylated CpG binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0047429	nucleoside triphosphate diphosphatase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0051864	histone H3K36 demethylase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0070097	delta-catenin binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0099122	RNA polymerase II C-terminal domain binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0140940	histone H2A methyltransferase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0141109	transporter activator activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:1990259	histone H2AQ104 methyltransferase activity	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:1990763	arrestin family protein binding	1/1388	10/18639	0.1	1.3428674351585	0.538860551262175	0.860402855513268
GO:0004806	triacylglycerol lipase activity	2/1388	24/18639	0.0833333333333333	1.11905619596542	0.542614384201136	0.861668681050644
GO:0019957	C-C chemokine binding	2/1388	24/18639	0.0833333333333333	1.11905619596542	0.542614384201136	0.861668681050644
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1388	24/18639	0.0833333333333333	1.11905619596542	0.542614384201136	0.861668681050644
GO:0070840	dynein complex binding	2/1388	24/18639	0.0833333333333333	1.11905619596542	0.542614384201136	0.861668681050644
GO:0004674	protein serine/threonine kinase activity	32/1388	433/18639	0.0739030023094688	0.992419351618292	0.545020218269973	0.863165319359993
GO:0008083	growth factor activity	12/1388	162/18639	0.0740740740740741	0.994716618635927	0.550893457843615	0.863165319359993
GO:0003697	single-stranded DNA binding	9/1388	121/18639	0.0743801652892562	0.998827017886489	0.551329349449691	0.863165319359993
GO:0016410	N-acyltransferase activity	7/1388	94/18639	0.074468085106383	1.00000766447974	0.556436091924166	0.863165319359993
GO:0043021	ribonucleoprotein complex binding	13/1388	177/18639	0.0734463276836158	0.98628681678308	0.562198299254965	0.863165319359993
GO:0005246	calcium channel regulator activity	4/1388	53/18639	0.0754716981132075	1.0134848567234	0.563593315920599	0.863165319359993
GO:0005544	calcium-dependent phospholipid binding	4/1388	53/18639	0.0754716981132075	1.0134848567234	0.563593315920599	0.863165319359993
GO:0038064	collagen receptor activity	4/1388	53/18639	0.0754716981132075	1.0134848567234	0.563593315920599	0.863165319359993
GO:0016500	protein-hormone receptor activity	5/1388	67/18639	0.0746268656716418	1.00213987698396	0.564690382777621	0.863165319359993
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/1388	67/18639	0.0746268656716418	1.00213987698396	0.564690382777621	0.863165319359993
GO:0004709	MAP kinase kinase kinase activity	2/1388	25/18639	0.08	1.0742939481268	0.565077055045146	0.863165319359993
GO:0005537	D-mannose binding	2/1388	25/18639	0.08	1.0742939481268	0.565077055045146	0.863165319359993
GO:0008139	nuclear localization sequence binding	2/1388	25/18639	0.08	1.0742939481268	0.565077055045146	0.863165319359993
GO:0008483	transaminase activity	2/1388	25/18639	0.08	1.0742939481268	0.565077055045146	0.863165319359993
GO:0015645	fatty acid ligase activity	2/1388	25/18639	0.08	1.0742939481268	0.565077055045146	0.863165319359993
GO:0120515	fatty acid-CoA ligase activity	2/1388	25/18639	0.08	1.0742939481268	0.565077055045146	0.863165319359993
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0002162	dystroglycan binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0003953	NAD+ nucleosidase activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0004016	adenylate cyclase activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0004954	prostanoid receptor activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0005536	D-glucose binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0008271	secondary active sulfate transmembrane transporter activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0008503	benzodiazepine receptor activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0010854	adenylate cyclase regulator activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0015217	ADP transmembrane transporter activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0019206	nucleoside kinase activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0019215	intermediate filament binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0031731	CCR6 chemokine receptor binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0034056	estrogen response element binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0070697	activin receptor binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0140537	transcription regulator activator activity	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:1900750	oligopeptide binding	1/1388	11/18639	0.0909090909090909	1.22078857741682	0.573218893355047	0.863165319359993
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	5/1388	68/18639	0.0735294117647059	0.987402525851839	0.57811165825792	0.869408230248345
GO:0004679	AMP-activated protein kinase activity	18/1388	248/18639	0.0725806451612903	0.974661848098912	0.580580116970571	0.869434694867764
GO:0030331	nuclear estrogen receptor binding	3/1388	40/18639	0.075	1.00715057636888	0.580812333116933	0.869434694867764
GO:0071949	FAD binding	3/1388	40/18639	0.075	1.00715057636888	0.580812333116933	0.869434694867764
GO:0008017	microtubule binding	20/1388	276/18639	0.072463768115942	0.973092344317755	0.584270257992427	0.869434694867764
GO:0005227	calcium-activated cation channel activity	2/1388	26/18639	0.0769230769230769	1.03297495012192	0.586733407639329	0.869434694867764
GO:0051139	metal cation:proton antiporter activity	2/1388	26/18639	0.0769230769230769	1.03297495012192	0.586733407639329	0.869434694867764
GO:0120014	phospholipid transfer activity	2/1388	26/18639	0.0769230769230769	1.03297495012192	0.586733407639329	0.869434694867764
GO:0008135	translation factor activity, RNA binding	6/1388	83/18639	0.072289156626506	0.970747543488073	0.590446594958617	0.869434694867764
GO:0140767	enzyme-substrate adaptor activity	10/1388	139/18639	0.0719424460431655	0.966091679970145	0.592062444671484	0.869434694867764
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/1388	41/18639	0.0731707317073171	0.982585928164757	0.597847582562805	0.869434694867764
GO:0043022	ribosome binding	8/1388	112/18639	0.0714285714285714	0.959191025113215	0.600921621902272	0.869434694867764
GO:0180051	translation factor activity	6/1388	84/18639	0.0714285714285714	0.959191025113215	0.602309654696443	0.869434694867764
GO:0003995	acyl-CoA dehydrogenase activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0004032	aldose reductase (NADPH) activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0005095	GTPase inhibitor activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0005165	neurotrophin receptor binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0005247	voltage-gated chloride channel activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0008179	adenylate cyclase binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0008504	monoamine transmembrane transporter activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0015132	prostaglandin transmembrane transporter activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0015269	calcium-activated potassium channel activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0016273	arginine N-methyltransferase activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0016274	protein-arginine N-methyltransferase activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0017166	vinculin binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0035197	siRNA binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0035251	UDP-glucosyltransferase activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0036009	protein-glutamine N-methyltransferase activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0045295	gamma-catenin binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0097371	MDM2/MDM4 family protein binding	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0140900	chloride:bicarbonate antiporter activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1388	12/18639	0.0833333333333333	1.11905619596542	0.60501898869664	0.869434694867764
GO:0015252	proton channel activity	2/1388	27/18639	0.0740740740740741	0.994716618635927	0.607578889054769	0.869891545952954
GO:0016405	CoA-ligase activity	2/1388	27/18639	0.0740740740740741	0.994716618635927	0.607578889054769	0.869891545952954
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/1388	27/18639	0.0740740740740741	0.994716618635927	0.607578889054769	0.869891545952954
GO:0004519	endonuclease activity	9/1388	127/18639	0.0708661417322835	0.951638339876103	0.61055464828851	0.872006884181382
GO:0019783	ubiquitin-like protein peptidase activity	9/1388	127/18639	0.0708661417322835	0.951638339876103	0.61055464828851	0.872006884181382
GO:0016758	hexosyltransferase activity	14/1388	197/18639	0.0710659898477157	0.954322035138021	0.611936149141872	0.872908918628847
GO:0016859	cis-trans isomerase activity	3/1388	42/18639	0.0714285714285714	0.959191025113215	0.614422755654457	0.87538321613438
GO:0045499	chemorepellent activity	2/1388	28/18639	0.0714285714285714	0.959191025113215	0.627614091937285	0.875998750405117
GO:0046625	sphingolipid binding	2/1388	28/18639	0.0714285714285714	0.959191025113215	0.627614091937285	0.875998750405117
GO:0051959	dynein light intermediate chain binding	2/1388	28/18639	0.0714285714285714	0.959191025113215	0.627614091937285	0.875998750405117
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/1388	28/18639	0.0714285714285714	0.959191025113215	0.627614091937285	0.875998750405117
GO:0004465	lipoprotein lipase activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0019104	DNA N-glycosylase activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0030955	potassium ion binding	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0031432	titin binding	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0031994	insulin-like growth factor I binding	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0032396	inhibitory MHC class I receptor activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0045159	myosin II binding	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0061459	L-arginine transmembrane transporter activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0070700	BMP receptor binding	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0140666	annealing activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0140852	histone ubiquitin ligase activity	1/1388	13/18639	0.0769230769230769	1.03297495012192	0.634451191611176	0.875998750405117
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/1388	58/18639	0.0689655172413793	0.926115472523104	0.635781519838761	0.875998750405117
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	17/1388	243/18639	0.0699588477366255	0.939454584267264	0.641707479461775	0.875998750405117
GO:0004521	RNA endonuclease activity	5/1388	73/18639	0.0684931506849315	0.919772215861987	0.641722473047464	0.875998750405117
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/1388	29/18639	0.0689655172413793	0.926115472523104	0.646844014404957	0.875998750405117
GO:0005416	amino acid:monoatomic cation symporter activity	2/1388	29/18639	0.0689655172413793	0.926115472523104	0.646844014404957	0.875998750405117
GO:0097472	cyclin-dependent protein kinase activity	2/1388	29/18639	0.0689655172413793	0.926115472523104	0.646844014404957	0.875998750405117
GO:0000287	magnesium ion binding	16/1388	230/18639	0.0695652173913043	0.934168650545044	0.648598138371249	0.875998750405117
GO:0004676	3-phosphoinositide-dependent protein kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0004711	ribosomal protein S6 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0035175	histone H3S10 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0035979	histone H2AXS139 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0044022	histone H3S28 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0044023	histone H4S1 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0044024	histone H2AS1 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0044025	histone H2BS14 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0072354	histone H3T3 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0072371	histone H2AS121 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0072518	Rho-dependent protein serine/threonine kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0140823	histone H2BS36 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0140855	histone H3S57 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0140995	histone H2A kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0140997	histone H4 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0140998	histone H2B kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:1990244	histone H2AT120 kinase activity	17/1388	245/18639	0.0693877551020408	0.931785567252838	0.655062601798063	0.875998750405117
GO:0140303	intramembrane lipid transporter activity	3/1388	45/18639	0.0666666666666667	0.895244956772334	0.661325723311694	0.875998750405117
GO:0004677	DNA-dependent protein kinase activity	17/1388	246/18639	0.0691056910569106	0.927997821044493	0.66164238760582	0.875998750405117
GO:0140857	histone H3T45 kinase activity	17/1388	246/18639	0.0691056910569106	0.927997821044493	0.66164238760582	0.875998750405117
GO:0005161	platelet-derived growth factor receptor binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0005347	ATP transmembrane transporter activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0008195	phosphatidate phosphatase activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0008559	ABC-type xenobiotic transporter activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0015926	glucosidase activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0032036	myosin heavy chain binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0032454	histone H3K9 demethylase activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0042043	neurexin family protein binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0043176	amine binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0070742	C2H2 zinc finger domain binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0098847	sequence-specific single stranded DNA binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:1901474	azole transmembrane transporter activity	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:1990825	sequence-specific mRNA binding	1/1388	14/18639	0.0714285714285714	0.959191025113215	0.661691701975381	0.875998750405117
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4/1388	60/18639	0.0666666666666667	0.895244956772334	0.662385182847989	0.875998750405117
GO:0015215	nucleotide transmembrane transporter activity	2/1388	30/18639	0.0666666666666667	0.895244956772334	0.665277401510415	0.875998750405117
GO:0022839	monoatomic ion-gated channel activity	2/1388	30/18639	0.0666666666666667	0.895244956772334	0.665277401510415	0.875998750405117
GO:0033612	receptor serine/threonine kinase binding	2/1388	30/18639	0.0666666666666667	0.895244956772334	0.665277401510415	0.875998750405117
GO:0048019	receptor antagonist activity	2/1388	30/18639	0.0666666666666667	0.895244956772334	0.665277401510415	0.875998750405117
GO:0098918	structural constituent of synapse	2/1388	30/18639	0.0666666666666667	0.895244956772334	0.665277401510415	0.875998750405117
GO:0035402	histone H3T11 kinase activity	17/1388	247/18639	0.0688259109311741	0.924240744845932	0.668155327086301	0.877802258158527
GO:0035403	histone H3T6 kinase activity	17/1388	247/18639	0.0688259109311741	0.924240744845932	0.668155327086301	0.877802258158527
GO:0106310	protein serine kinase activity	25/1388	361/18639	0.0692520775623269	0.929963597755195	0.677528940247233	0.884464391823329
GO:0016878	acid-thiol ligase activity	2/1388	31/18639	0.0645161290322581	0.866366087199033	0.682926160237688	0.884464391823329
GO:0047499	calcium-independent phospholipase A2 activity	2/1388	31/18639	0.0645161290322581	0.866366087199033	0.682926160237688	0.884464391823329
GO:0070273	phosphatidylinositol-4-phosphate binding	2/1388	31/18639	0.0645161290322581	0.866366087199033	0.682926160237688	0.884464391823329
GO:0004559	alpha-mannosidase activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0004953	icosanoid receptor activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0015116	sulfate transmembrane transporter activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0033130	acetylcholine receptor binding	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0034483	heparan sulfate sulfotransferase activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0048531	beta-1,3-galactosyltransferase activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0050700	CARD domain binding	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0051371	muscle alpha-actinin binding	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0141050	histone H3K deacetylase activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0141051	histone H4K deacetylase activity	1/1388	15/18639	0.0666666666666667	0.895244956772334	0.686903617017431	0.884464391823329
GO:0015106	bicarbonate transmembrane transporter activity	2/1388	32/18639	0.0625	0.839292146974063	0.699804840745775	0.89908701393828
GO:0070717	poly-purine tract binding	2/1388	32/18639	0.0625	0.839292146974063	0.699804840745775	0.89908701393828
GO:0046873	metal ion transmembrane transporter activity	31/1388	450/18639	0.0688888888888889	0.925086455331412	0.701849602592934	0.899606556820698
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1388	48/18639	0.0625	0.839292146974063	0.703949368939704	0.899606556820698
GO:0008094	ATP-dependent activity, acting on DNA	14/1388	210/18639	0.0666666666666667	0.895244956772334	0.705260664095441	0.899606556820698
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0005149	interleukin-1 receptor binding	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0005521	lamin binding	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0008142	oxysterol binding	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0015562	efflux transmembrane transporter activity	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0140327	flippase activity	1/1388	16/18639	0.0625	0.839292146974063	0.710237905010332	0.899606556820698
GO:0141003	histone H2AX kinase activity	24/1388	354/18639	0.0677966101694915	0.910418600107459	0.714375966399468	0.899606556820698
GO:0005004	GPI-linked ephrin receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0005008	hepatocyte growth factor receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0005009	insulin receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0005011	macrophage colony-stimulating factor receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0005020	stem cell factor receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0008288	boss receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0036332	placental growth factor receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0038062	protein tyrosine kinase collagen receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0060175	brain-derived neurotrophic factor receptor activity	3/1388	49/18639	0.0612244897959184	0.822163735811327	0.717212100283168	0.899606556820698
GO:0005506	iron ion binding	10/1388	154/18639	0.0649350649350649	0.871991841012014	0.71853548396695	0.900296343743305
GO:0004222	metalloendopeptidase activity	7/1388	110/18639	0.0636363636363636	0.854552004191774	0.720064023624202	0.901241423116744
GO:0017171	serine hydrolase activity	13/1388	198/18639	0.0656565656565657	0.881680639245481	0.72124515178424	0.90143400311903
GO:0140996	histone H3 kinase activity	24/1388	357/18639	0.0672268907563025	0.902768023635967	0.729358070650313	0.90143400311903
GO:0005006	epidermal growth factor receptor activity	3/1388	50/18639	0.06	0.805720461095101	0.730009050537195	0.90143400311903
GO:0005007	fibroblast growth factor receptor activity	3/1388	50/18639	0.06	0.805720461095101	0.730009050537195	0.90143400311903
GO:0005017	platelet-derived growth factor receptor activity	3/1388	50/18639	0.06	0.805720461095101	0.730009050537195	0.90143400311903
GO:0005019	platelet-derived growth factor beta-receptor activity	3/1388	50/18639	0.06	0.805720461095101	0.730009050537195	0.90143400311903
GO:0015605	organophosphate ester transmembrane transporter activity	3/1388	50/18639	0.06	0.805720461095101	0.730009050537195	0.90143400311903
GO:0008376	acetylgalactosaminyltransferase activity	2/1388	34/18639	0.0588235294117647	0.789922020681472	0.731320682528969	0.90143400311903
GO:0015035	protein-disulfide reductase activity	2/1388	34/18639	0.0588235294117647	0.789922020681472	0.731320682528969	0.90143400311903
GO:0008569	minus-end-directed microtubule motor activity	1/1388	17/18639	0.0588235294117647	0.789922020681472	0.731834306655914	0.90143400311903
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/1388	17/18639	0.0588235294117647	0.789922020681472	0.731834306655914	0.90143400311903
GO:0016018	cyclosporin A binding	1/1388	17/18639	0.0588235294117647	0.789922020681472	0.731834306655914	0.90143400311903
GO:0017110	nucleoside diphosphate phosphatase activity	1/1388	17/18639	0.0588235294117647	0.789922020681472	0.731834306655914	0.90143400311903
GO:0032183	SUMO binding	1/1388	17/18639	0.0588235294117647	0.789922020681472	0.731834306655914	0.90143400311903
GO:0036041	long-chain fatty acid binding	1/1388	17/18639	0.0588235294117647	0.789922020681472	0.731834306655914	0.90143400311903
GO:0003743	translation initiation factor activity	3/1388	51/18639	0.0588235294117647	0.789922020681472	0.742346024698117	0.909385294821144
GO:0005030	neurotrophin receptor activity	3/1388	51/18639	0.0588235294117647	0.789922020681472	0.742346024698117	0.909385294821144
GO:0016830	carbon-carbon lyase activity	3/1388	51/18639	0.0588235294117647	0.789922020681472	0.742346024698117	0.909385294821144
GO:0035173	histone kinase activity	24/1388	360/18639	0.0666666666666667	0.895244956772334	0.743856363120961	0.909385294821144
GO:0004623	phospholipase A2 activity	2/1388	35/18639	0.0571428571428571	0.767352820090572	0.745996290674347	0.909385294821144
GO:0005343	organic acid:sodium symporter activity	2/1388	35/18639	0.0571428571428571	0.767352820090572	0.745996290674347	0.909385294821144
GO:0010485	histone H4 acetyltransferase activity	2/1388	35/18639	0.0571428571428571	0.767352820090572	0.745996290674347	0.909385294821144
GO:0140566	histone reader activity	2/1388	35/18639	0.0571428571428571	0.767352820090572	0.745996290674347	0.909385294821144
GO:0008308	voltage-gated monoatomic anion channel activity	1/1388	18/18639	0.0555555555555556	0.746037463976945	0.751822169525723	0.909385294821144
GO:0008409	5'-3' exonuclease activity	1/1388	18/18639	0.0555555555555556	0.746037463976945	0.751822169525723	0.909385294821144
GO:0015280	ligand-gated sodium channel activity	1/1388	18/18639	0.0555555555555556	0.746037463976945	0.751822169525723	0.909385294821144
GO:0017075	syntaxin-1 binding	1/1388	18/18639	0.0555555555555556	0.746037463976945	0.751822169525723	0.909385294821144
GO:0031690	adrenergic receptor binding	1/1388	18/18639	0.0555555555555556	0.746037463976945	0.751822169525723	0.909385294821144
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/1388	18/18639	0.0555555555555556	0.746037463976945	0.751822169525723	0.909385294821144
GO:0003777	microtubule motor activity	4/1388	68/18639	0.0588235294117647	0.789922020681472	0.755208976278222	0.909385294821144
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/1388	36/18639	0.0555555555555556	0.746037463976945	0.759978043075238	0.909385294821144
GO:0045505	dynein intermediate chain binding	2/1388	36/18639	0.0555555555555556	0.746037463976945	0.759978043075238	0.909385294821144
GO:0035401	histone H3Y41 kinase activity	7/1388	115/18639	0.0608695652173913	0.817397569226914	0.761738358565855	0.909385294821144
GO:0140801	histone H2AXY142 kinase activity	7/1388	115/18639	0.0608695652173913	0.817397569226914	0.761738358565855	0.909385294821144
GO:0008080	N-acetyltransferase activity	4/1388	69/18639	0.0579710144927536	0.778473875454204	0.765295079440936	0.909385294821144
GO:0004864	protein phosphatase inhibitor activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0005003	ephrin receptor activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0005005	transmembrane-ephrin receptor activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0008146	sulfotransferase activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0016251	RNA polymerase II general transcription initiation factor activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0016860	intramolecular oxidoreductase activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0034212	protein N-acetyltransferase activity	3/1388	53/18639	0.0566037735849057	0.760113642542548	0.76566798455338	0.909385294821144
GO:0140097	catalytic activity, acting on DNA	22/1388	336/18639	0.0654761904761905	0.879258439687114	0.765869263870961	0.909385294821144
GO:0015294	solute:monoatomic cation symporter activity	7/1388	116/18639	0.0603448275862069	0.810351038457716	0.769508057649639	0.909385294821144
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0008574	plus-end-directed microtubule motor activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0031420	alkali metal ion binding	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0034987	immunoglobulin receptor binding	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0042577	lipid phosphatase activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0046527	glucosyltransferase activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0050145	nucleoside monophosphate kinase activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0140036	ubiquitin-modified protein reader activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0141147	intracellularly calcium-gated channel activity	1/1388	19/18639	0.0526315789473684	0.706772334293948	0.770321220527189	0.909385294821144
GO:0019213	deacetylase activity	2/1388	37/18639	0.0540540540540541	0.725874289274866	0.773287813264533	0.911039488501939
GO:0042805	actinin binding	2/1388	37/18639	0.0540540540540541	0.725874289274866	0.773287813264533	0.911039488501939
GO:0005179	hormone activity	8/1388	132/18639	0.0606060606060606	0.813859051611213	0.775340900684924	0.91240335957093
GO:0050661	NADP binding	3/1388	54/18639	0.0555555555555556	0.746037463976945	0.776668947881731	0.91240335957093
GO:0050660	flavin adenine dinucleotide binding	5/1388	86/18639	0.0581395348837209	0.780736880906105	0.776797018328859	0.91240335957093
GO:0005501	retinoid binding	2/1388	38/18639	0.0526315789473684	0.706772334293948	0.785948066541389	0.917256815202826
GO:0019840	isoprenoid binding	2/1388	38/18639	0.0526315789473684	0.706772334293948	0.785948066541389	0.917256815202826
GO:0008236	serine-type peptidase activity	12/1388	194/18639	0.0618556701030928	0.830639650613506	0.787351539598243	0.917256815202826
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/1388	20/18639	0.05	0.671433717579251	0.787442280994872	0.917256815202826
GO:0005326	neurotransmitter transmembrane transporter activity	1/1388	20/18639	0.05	0.671433717579251	0.787442280994872	0.917256815202826
GO:0010851	cyclase regulator activity	1/1388	20/18639	0.05	0.671433717579251	0.787442280994872	0.917256815202826
GO:0061608	nuclear import signal receptor activity	1/1388	20/18639	0.05	0.671433717579251	0.787442280994872	0.917256815202826
GO:0140939	histone H4 methyltransferase activity	1/1388	20/18639	0.05	0.671433717579251	0.787442280994872	0.917256815202826
GO:0004518	nuclease activity	13/1388	209/18639	0.062200956937799	0.835276395074666	0.788021318902772	0.917256815202826
GO:0019212	phosphatase inhibitor activity	3/1388	56/18639	0.0535714285714286	0.719393268834912	0.797395690576157	0.922575019959373
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/1388	39/18639	0.0512820512820513	0.688649966747949	0.797981650737126	0.922575019959373
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/1388	39/18639	0.0512820512820513	0.688649966747949	0.797981650737126	0.922575019959373
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	11/1388	181/18639	0.0607734806629834	0.816107281035553	0.798682615018537	0.922575019959373
GO:0003727	single-stranded RNA binding	5/1388	89/18639	0.0561797752808989	0.754419907392416	0.801652293365953	0.922575019959373
GO:0005248	voltage-gated sodium channel activity	1/1388	21/18639	0.0476190476190476	0.63946068340881	0.803287928665484	0.922575019959373
GO:0009975	cyclase activity	1/1388	21/18639	0.0476190476190476	0.63946068340881	0.803287928665484	0.922575019959373
GO:0015174	basic amino acid transmembrane transporter activity	1/1388	21/18639	0.0476190476190476	0.63946068340881	0.803287928665484	0.922575019959373
GO:0035613	RNA stem-loop binding	1/1388	21/18639	0.0476190476190476	0.63946068340881	0.803287928665484	0.922575019959373
GO:0036122	BMP binding	1/1388	21/18639	0.0476190476190476	0.63946068340881	0.803287928665484	0.922575019959373
GO:0051428	peptide hormone receptor binding	1/1388	21/18639	0.0476190476190476	0.63946068340881	0.803287928665484	0.922575019959373
GO:0004540	RNA nuclease activity	7/1388	121/18639	0.0578512396694215	0.776865458356158	0.805573956697532	0.922575019959373
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/1388	57/18639	0.0526315789473684	0.706772334293948	0.807140968273992	0.922575019959373
GO:0004532	RNA exonuclease activity	2/1388	40/18639	0.05	0.671433717579251	0.809411614822399	0.922575019959373
GO:0004407	histone deacetylase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0032931	histone H3K56 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0033558	protein lysine deacetylase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0043992	histone H3K9 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0043993	histone H3K18 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0043994	histone H3K23 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0043999	histone H2AK5 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0044012	histone H2AK9 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0044014	histone H2BK5 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0044015	histone H2BK12 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0044016	histone H3K4 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0044017	histone H3K27 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0044018	histone H3K36 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0046972	histone H4K16 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0070034	telomerase RNA binding	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0140035	ubiquitin-like protein reader activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0140908	histone H3K122 acetyltransferase activity	1/1388	22/18639	0.0454545454545455	0.61039428870841	0.817953110479444	0.922575019959373
GO:0008137	NADH dehydrogenase (ubiquinone) activity	2/1388	41/18639	0.0487804878048781	0.655057285443171	0.820261052374174	0.924282541107007
GO:0140034	methylation-dependent protein binding	4/1388	76/18639	0.0526315789473684	0.706772334293948	0.827007984150471	0.926216197393502
GO:0042393	histone binding	15/1388	247/18639	0.0607287449392713	0.81550653956994	0.828411993413519	0.926216197393502
GO:0004402	histone acetyltransferase activity	2/1388	42/18639	0.0476190476190476	0.63946068340881	0.830552967210159	0.926216197393502
GO:0031492	nucleosomal DNA binding	2/1388	42/18639	0.0476190476190476	0.63946068340881	0.830552967210159	0.926216197393502
GO:0000295	adenine nucleotide transmembrane transporter activity	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0003887	DNA-directed DNA polymerase activity	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0005212	structural constituent of eye lens	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0016493	C-C chemokine receptor activity	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0031681	G-protein beta-subunit binding	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0044013	histone H2B acetyltransferase activity	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0070577	lysine-acetylated histone binding	1/1388	23/18639	0.0434782608695652	0.583855406590653	0.831525709859287	0.926216197393502
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/1388	43/18639	0.0465116279069767	0.624589504724884	0.840310158761079	0.934213013178506
GO:0005245	voltage-gated calcium channel activity	2/1388	43/18639	0.0465116279069767	0.624589504724884	0.840310158761079	0.934213013178506
GO:0005540	hyaluronic acid binding	1/1388	24/18639	0.0416666666666667	0.559528097982709	0.844087071844424	0.934840486800104
GO:0043998	histone H2A acetyltransferase activity	1/1388	24/18639	0.0416666666666667	0.559528097982709	0.844087071844424	0.934840486800104
GO:0048027	mRNA 5'-UTR binding	1/1388	24/18639	0.0416666666666667	0.559528097982709	0.844087071844424	0.934840486800104
GO:0140033	acetylation-dependent protein binding	1/1388	24/18639	0.0416666666666667	0.559528097982709	0.844087071844424	0.934840486800104
GO:0003954	NADH dehydrogenase activity	2/1388	44/18639	0.0454545454545455	0.61039428870841	0.849555124989642	0.939109368934419
GO:0019205	nucleobase-containing compound kinase activity	2/1388	44/18639	0.0454545454545455	0.61039428870841	0.849555124989642	0.939109368934419
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/1388	25/18639	0.04	0.537146974063401	0.85571248921106	0.944122594731445
GO:0017056	structural constituent of nuclear pore	1/1388	25/18639	0.04	0.537146974063401	0.85571248921106	0.944122594731445
GO:0015293	symporter activity	8/1388	146/18639	0.0547945205479452	0.73581777268959	0.859379493902605	0.94727057850628
GO:0004435	phosphatidylinositol phospholipase C activity	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0004529	DNA exonuclease activity	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0005112	Notch binding	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0008143	poly(A) binding	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0008157	protein phosphatase 1 binding	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0015216	purine nucleotide transmembrane transporter activity	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0034237	protein kinase A regulatory subunit binding	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0097602	cullin family protein binding	1/1388	26/18639	0.0384615384615385	0.516487475060962	0.86647165247393	0.947906958157569
GO:0019843	rRNA binding	3/1388	65/18639	0.0461538461538462	0.619784970073155	0.871674681769789	0.952533551213492
GO:0008509	monoatomic anion transmembrane transporter activity	8/1388	149/18639	0.0536912751677852	0.721002649749531	0.873613069358159	0.952533551213492
GO:0015103	inorganic anion transmembrane transporter activity	9/1388	165/18639	0.0545454545454545	0.732473146450092	0.873718552964166	0.952533551213492
GO:0061733	protein-lysine-acetyltransferase activity	2/1388	47/18639	0.0425531914893617	0.571432951131277	0.874435512618935	0.952533551213492
GO:0005104	fibroblast growth factor receptor binding	1/1388	27/18639	0.037037037037037	0.497358309317963	0.87642906645159	0.952533551213492
GO:0008266	poly(U) RNA binding	1/1388	27/18639	0.037037037037037	0.497358309317963	0.87642906645159	0.952533551213492
GO:0008395	steroid hydroxylase activity	1/1388	27/18639	0.037037037037037	0.497358309317963	0.87642906645159	0.952533551213492
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/1388	48/18639	0.0416666666666667	0.559528097982709	0.881847953648467	0.957528934745163
GO:0008527	taste receptor activity	1/1388	28/18639	0.0357142857142857	0.479595512556608	0.885644435878045	0.958967556615855
GO:0036408	histone H3K14 acetyltransferase activity	1/1388	28/18639	0.0357142857142857	0.479595512556608	0.885644435878045	0.958967556615855
GO:0051393	alpha-actinin binding	1/1388	28/18639	0.0357142857142857	0.479595512556608	0.885644435878045	0.958967556615855
GO:0099094	ligand-gated monoatomic cation channel activity	7/1388	136/18639	0.0514705882352941	0.691181768096287	0.887968810914614	0.960590795450382
GO:0005253	monoatomic anion channel activity	5/1388	103/18639	0.0485436893203883	0.65187739570801	0.8898873461425	0.961487914129548
GO:0140223	general transcription initiation factor activity	3/1388	68/18639	0.0441176470588235	0.592441515511104	0.890450147278052	0.961487914129548
GO:0004629	phospholipase C activity	1/1388	29/18639	0.0344827586206897	0.463057736261552	0.894173022359227	0.963719812987167
GO:0010484	histone H3 acetyltransferase activity	1/1388	29/18639	0.0344827586206897	0.463057736261552	0.894173022359227	0.963719812987167
GO:0008081	phosphoric diester hydrolase activity	4/1388	87/18639	0.0459770114942529	0.617410315015403	0.896380905079976	0.964191730642667
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	6/1388	122/18639	0.0491803278688525	0.660426607455001	0.899177523755556	0.964191730642667
GO:0016782	transferase activity, transferring sulphur-containing groups	3/1388	70/18639	0.0428571428571429	0.575514615067929	0.901560741423865	0.964191730642667
GO:0005272	sodium channel activity	2/1388	51/18639	0.0392156862745098	0.526614680454314	0.901722313696071	0.964191730642667
GO:0008187	poly-pyrimidine tract binding	1/1388	30/18639	0.0333333333333333	0.447622478386167	0.902065974802289	0.964191730642667
GO:0043995	histone H4K5 acetyltransferase activity	1/1388	30/18639	0.0333333333333333	0.447622478386167	0.902065974802289	0.964191730642667
GO:0043996	histone H4K8 acetyltransferase activity	1/1388	30/18639	0.0333333333333333	0.447622478386167	0.902065974802289	0.964191730642667
GO:0043997	histone H4K12 acetyltransferase activity	1/1388	30/18639	0.0333333333333333	0.447622478386167	0.902065974802289	0.964191730642667
GO:0070566	adenylyltransferase activity	1/1388	30/18639	0.0333333333333333	0.447622478386167	0.902065974802289	0.964191730642667
GO:0004497	monooxygenase activity	5/1388	106/18639	0.0471698113207547	0.633428035452123	0.903638248024255	0.96498616578003
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/1388	31/18639	0.032258064516129	0.433183043599517	0.909370635287776	0.968442286802353
GO:0008327	methyl-CpG binding	1/1388	31/18639	0.032258064516129	0.433183043599517	0.909370635287776	0.968442286802353
GO:0017147	Wnt-protein binding	1/1388	31/18639	0.032258064516129	0.433183043599517	0.909370635287776	0.968442286802353
GO:0017046	peptide hormone binding	2/1388	53/18639	0.0377358490566038	0.506742428361699	0.913188839113793	0.971619569221623
GO:0030515	snoRNA binding	1/1388	32/18639	0.03125	0.419646073487032	0.916130822208486	0.972084117639633
GO:0047498	calcium-dependent phospholipase A2 activity	1/1388	32/18639	0.03125	0.419646073487032	0.916130822208486	0.972084117639633
GO:0140142	nucleocytoplasmic carrier activity	1/1388	32/18639	0.03125	0.419646073487032	0.916130822208486	0.972084117639633
GO:0017069	snRNA binding	2/1388	54/18639	0.037037037037037	0.497358309317963	0.91843960416118	0.973646356323874
GO:0035064	methylated histone binding	3/1388	74/18639	0.0405405405405405	0.544405716956149	0.920779373201161	0.975238571798135
GO:0042923	neuropeptide binding	1/1388	33/18639	0.0303030303030303	0.406929525805607	0.922387092363515	0.976053250464665
GO:0015081	sodium ion transmembrane transporter activity	8/1388	164/18639	0.0487804878048781	0.655057285443171	0.928084904336806	0.977735754639099
GO:0015020	glucuronosyltransferase activity	1/1388	34/18639	0.0294117647058824	0.394961010340736	0.928176983570622	0.977735754639099
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/1388	34/18639	0.0294117647058824	0.394961010340736	0.928176983570622	0.977735754639099
GO:0016831	carboxy-lyase activity	1/1388	34/18639	0.0294117647058824	0.394961010340736	0.928176983570622	0.977735754639099
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1388	34/18639	0.0294117647058824	0.394961010340736	0.928176983570622	0.977735754639099
GO:0005261	monoatomic cation channel activity	19/1388	341/18639	0.0557184750733138	0.748225257126438	0.929399021455962	0.978137848982586
GO:0000175	3'-5'-RNA exonuclease activity	1/1388	35/18639	0.0285714285714286	0.383676410045286	0.933535239244042	0.97983319971151
GO:0034061	DNA polymerase activity	1/1388	35/18639	0.0285714285714286	0.383676410045286	0.933535239244042	0.97983319971151
GO:0043015	gamma-tubulin binding	1/1388	35/18639	0.0285714285714286	0.383676410045286	0.933535239244042	0.97983319971151
GO:0019842	vitamin binding	7/1388	150/18639	0.0466666666666667	0.626671469740634	0.936227114265662	0.980743629185144
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/1388	36/18639	0.0277777777777778	0.373018731988473	0.938494016277436	0.980743629185144
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/1388	36/18639	0.0277777777777778	0.373018731988473	0.938494016277436	0.980743629185144
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/1388	36/18639	0.0277777777777778	0.373018731988473	0.938494016277436	0.980743629185144
GO:0005201	extracellular matrix structural constituent	8/1388	168/18639	0.0476190476190476	0.63946068340881	0.938615466419459	0.980743629185144
GO:0015370	solute:sodium symporter activity	3/1388	79/18639	0.0379746835443038	0.50994965892095	0.93996215594516	0.980946899998263
GO:0036002	pre-mRNA binding	2/1388	59/18639	0.0338983050847458	0.455209300053729	0.940495481441633	0.980946899998263
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/1388	60/18639	0.0333333333333333	0.447622478386167	0.944166733991732	0.983894430050471
GO:0005109	frizzled binding	1/1388	38/18639	0.0263157894736842	0.353386167146974	0.94732996965956	0.985426349136486
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/1388	38/18639	0.0263157894736842	0.353386167146974	0.94732996965956	0.985426349136486
GO:0005254	chloride channel activity	3/1388	83/18639	0.036144578313253	0.485373771744037	0.952107598154194	0.988674134834217
GO:0015108	chloride transmembrane transporter activity	5/1388	121/18639	0.0413223140495868	0.554903898825827	0.952150949440857	0.988674134834217
GO:0004527	exonuclease activity	3/1388	84/18639	0.0357142857142857	0.479595512556608	0.954763429331668	0.989699246229933
GO:0015144	carbohydrate transmembrane transporter activity	1/1388	40/18639	0.025	0.335716858789625	0.954897331495396	0.989699246229933
GO:0004252	serine-type endopeptidase activity	8/1388	176/18639	0.0454545454545455	0.61039428870841	0.955688962854333	0.989699246229933
GO:0008307	structural constituent of muscle	1/1388	42/18639	0.0238095238095238	0.319730341704405	0.961378123138384	0.994705898073848
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1388	43/18639	0.0232558139534884	0.312294752362442	0.964260693718796	0.996802351233285
GO:0015276	ligand-gated monoatomic ion channel activity	8/1388	186/18639	0.043010752688172	0.577577391466022	0.970992907299996	0.999999825356889
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1388	46/18639	0.0217391304347826	0.291927703295326	0.971681317379991	0.999999825356889
GO:0140299	molecular sensor activity	2/1388	71/18639	0.028169014084507	0.378272516946057	0.972613838324961	0.999999825356889
GO:0022834	ligand-gated channel activity	8/1388	188/18639	0.0425531914893617	0.571432951131277	0.973404211932897	0.999999825356889
GO:0099095	ligand-gated monoatomic anion channel activity	1/1388	47/18639	0.0212765957446809	0.285716475565639	0.973795356613927	0.999999825356889
GO:0140938	histone H3 methyltransferase activity	1/1388	47/18639	0.0212765957446809	0.285716475565639	0.973795356613927	0.999999825356889
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/1388	48/18639	0.0208333333333333	0.279764048991354	0.975751684336597	0.999999825356889
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/1388	73/18639	0.0273972602739726	0.367908886344795	0.975990503936932	0.999999825356889
GO:0003684	damaged DNA binding	2/1388	74/18639	0.027027027027027	0.362937144637433	0.97752414645737	0.999999825356889
GO:0031491	nucleosome binding	2/1388	74/18639	0.027027027027027	0.362937144637433	0.97752414645737	0.999999825356889
GO:0003730	mRNA 3'-UTR binding	12/1388	262/18639	0.0458015267175573	0.615053787095497	0.977623290108792	0.999999825356889
GO:0022832	voltage-gated channel activity	7/1388	175/18639	0.04	0.537146974063401	0.9788545852258	0.999999825356889
GO:0005216	monoatomic ion channel activity	23/1388	448/18639	0.0513392857142857	0.689418549300123	0.980525680047513	0.999999825356889
GO:0140098	catalytic activity, acting on RNA	19/1388	387/18639	0.0490956072351421	0.659288921654045	0.982971032961547	0.999999825356889
GO:0022843	voltage-gated monoatomic cation channel activity	5/1388	143/18639	0.034965034965035	0.469534068237238	0.984239349619236	0.999999825356889
GO:0001653	peptide receptor activity	4/1388	128/18639	0.03125	0.419646073487032	0.988143763558831	0.999999825356889
GO:0008408	3'-5' exonuclease activity	1/1388	58/18639	0.0172413793103448	0.231528868130776	0.988841363886229	0.999999825356889
GO:0005244	voltage-gated monoatomic ion channel activity	6/1388	173/18639	0.0346820809248555	0.465734370575203	0.990773182409262	0.999999825356889
GO:0042054	histone methyltransferase activity	1/1388	67/18639	0.0149253731343284	0.200427975396791	0.994452639581902	0.999999825356889
GO:0030594	neurotransmitter receptor activity	2/1388	97/18639	0.0206185567010309	0.276879883537835	0.995234737707541	0.999999825356889
GO:0016279	protein-lysine N-methyltransferase activity	1/1388	69/18639	0.0144927536231884	0.194618468863551	0.995250852343519	0.999999825356889
GO:0022836	gated channel activity	13/1388	318/18639	0.0408805031446541	0.548970964058507	0.995263544312066	0.999999825356889
GO:0008528	G protein-coupled peptide receptor activity	3/1388	122/18639	0.0245901639344262	0.3302133037275	0.995439732744504	0.999999825356889
GO:0008170	N-methyltransferase activity	2/1388	98/18639	0.0204081632653061	0.274054578603776	0.995550908591132	0.999999825356889
GO:0016278	lysine N-methyltransferase activity	1/1388	70/18639	0.0142857142857143	0.191838205022643	0.995605823638468	0.999999825356889
GO:0016874	ligase activity	5/1388	167/18639	0.029940119760479	0.402056118310929	0.995705898816141	0.999999825356889
GO:0005267	potassium channel activity	3/1388	124/18639	0.0241935483870968	0.324887282699637	0.995980522878074	0.999999825356889
GO:0003735	structural constituent of ribosome	5/1388	175/18639	0.0285714285714286	0.383676410045286	0.997262600484517	0.999999825356889
GO:0000049	tRNA binding	1/1388	80/18639	0.0125	0.167858429394813	0.997979812666121	0.999999825356889
GO:0015079	potassium ion transmembrane transporter activity	4/1388	160/18639	0.025	0.335716858789625	0.998191176384149	0.999999825356889
GO:0008276	protein methyltransferase activity	1/1388	95/18639	0.0105263157894737	0.14135446685879	0.999370771815206	0.999999825356889
GO:0005249	voltage-gated potassium channel activity	1/1388	98/18639	0.0102040816326531	0.137027289301888	0.999501757993787	0.999999825356889
GO:0140101	catalytic activity, acting on a tRNA	2/1388	139/18639	0.0143884892086331	0.193218335994029	0.999749184579805	0.999999825356889
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/1388	167/18639	0.0119760479041916	0.160822447324371	0.999966531404132	0.999999825356889
GO:0008168	methyltransferase activity	3/1388	204/18639	0.0147058823529412	0.197480505170368	0.999980301349649	0.999999825356889
GO:0016741	transferase activity, transferring one-carbon groups	3/1388	215/18639	0.013953488372093	0.187376851417465	0.9999907964786	0.999999825356889
GO:0045182	translation regulator activity	7/1388	356/18639	0.0196629213483146	0.264046967587346	0.999999152669872	0.999999825356889
GO:0030371	translation repressor activity	5/1388	329/18639	0.0151975683890578	0.204083196832599	0.999999825356889	0.999999825356889