ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 31/946 175/18639 0.177142857142857 3.49023859861069 1.0114836525105e-09 1.04486261304335e-06 GO:0023026 MHC class II protein complex binding 11/946 27/18639 0.407407407407407 8.02713178294574 3.34770427493752e-08 1.72908925800523e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 21/946 118/18639 0.177966101694915 3.50645895295087 4.59020278301284e-07 0.000158055982495075 GO:0015078 proton transmembrane transporter activity 27/946 185/18639 0.145945945945946 2.87556711045083 7.29304660383661e-07 0.00018834292854408 GO:0045296 cadherin binding 39/946 334/18639 0.116766467065868 2.30064501019103 1.11750906809905e-06 0.000202896587914206 GO:0098641 cadherin binding involved in cell-cell adhesion 8/946 18/18639 0.444444444444444 8.7568710359408 1.18640657675787e-06 0.000202896587914206 GO:0023023 MHC protein complex binding 11/946 37/18639 0.297297297297297 5.85763670647392 1.37490427434602e-06 0.000202896587914206 GO:0042605 peptide antigen binding 12/946 45/18639 0.266666666666667 5.25412262156448 1.65659892723155e-06 0.000213908336478774 GO:0032395 MHC class II receptor activity 6/946 10/18639 0.6 11.8217758985201 2.96343995671161e-06 0.000340137052809232 GO:0048306 calcium-dependent protein binding 15/946 80/18639 0.1875 3.69430496828753 1.02413989359722e-05 0.00105793651008593 GO:0042625 ATPase-coupled ion transmembrane transporter activity 8/946 24/18639 0.333333333333333 6.5676532769556 1.51809722550522e-05 0.00120630341072838 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 8/946 24/18639 0.333333333333333 6.5676532769556 1.51809722550522e-05 0.00120630341072838 GO:0046961 proton-transporting ATPase activity, rotational mechanism 8/946 24/18639 0.333333333333333 6.5676532769556 1.51809722550522e-05 0.00120630341072838 GO:0031625 ubiquitin protein ligase binding 33/946 302/18639 0.109271523178808 2.15297243184968 2.91804495143926e-05 0.00215310031059769 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 13/946 68/18639 0.191176470588235 3.76674232060689 3.183772972898e-05 0.00219255832066909 GO:0015399 primary active transmembrane transporter activity 22/946 166/18639 0.132530120481928 2.61123564023536 3.55612333096219e-05 0.00229592212555247 GO:0009055 electron transfer activity 17/946 116/18639 0.146551724137931 2.88750273383393 7.61145957042033e-05 0.00462508102132012 GO:0044389 ubiquitin-like protein ligase binding 33/946 322/18639 0.102484472049689 2.01924743608262 0.000103082022963777 0.00591576276231012 GO:0008429 phosphatidylethanolamine binding 6/946 17/18639 0.352941176470588 6.95398582265887 0.000128428281098042 0.00698244286180407 GO:0042277 peptide binding 27/946 249/18639 0.108433734939759 2.13646552382893 0.000170954160759298 0.00882978240321775 GO:0004859 phospholipase inhibitor activity 5/946 12/18639 0.416666666666667 8.2095665961945 0.000195655167633296 0.00962437086500928 GO:0003924 GTPase activity 32/946 331/18639 0.0966767371601208 1.90481786884513 0.000374577334023374 0.017588108456643 GO:0043394 proteoglycan binding 8/946 37/18639 0.216216216216216 4.26009942289012 0.00044294240134113 0.0198938913297995 GO:0004129 cytochrome-c oxidase activity 5/946 15/18639 0.333333333333333 6.5676532769556 0.000652946901497307 0.0281039228852799 GO:0033218 amide binding 25/946 247/18639 0.101214574898785 1.99422670352903 0.000817282757752983 0.0324247077734826 GO:0005126 cytokine receptor binding 27/946 275/18639 0.0981818181818182 1.93447241975783 0.000823276133460202 0.0324247077734826 GO:0000062 fatty-acyl-CoA binding 5/946 16/18639 0.3125 6.15717494714588 0.000910277372150043 0.0324247077734826 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/946 16/18639 0.3125 6.15717494714588 0.000910277372150043 0.0324247077734826 GO:0055102 lipase inhibitor activity 5/946 16/18639 0.3125 6.15717494714588 0.000910277372150043 0.0324247077734826 GO:0001540 amyloid-beta binding 12/946 83/18639 0.144578313253012 2.84862069843857 0.000947410198244718 0.0326224911595598 GO:0048487 beta-tubulin binding 8/946 42/18639 0.19047619047619 3.75294472968892 0.00108185340675738 0.0349409051266123 GO:0005131 growth hormone receptor binding 4/946 10/18639 0.4 7.88118393234672 0.00108239009104704 0.0349409051266123 GO:0140311 protein sequestering activity 7/946 33/18639 0.212121212121212 4.17941572169902 0.00113573655718636 0.035551995865864 GO:0005507 copper ion binding 10/946 63/18639 0.158730158730159 3.12745394140743 0.00119375538669189 0.0362690974839037 GO:1901567 fatty acid derivative binding 5/946 17/18639 0.294117647058824 5.79498818554906 0.00123604782675504 0.0364810687153703 GO:0016209 antioxidant activity 12/946 86/18639 0.13953488372093 2.74925020895816 0.00130178164775692 0.0373539011703583 GO:0019003 GDP binding 11/946 75/18639 0.146666666666667 2.88976744186047 0.00135281572278178 0.0377691524765831 GO:0098631 cell adhesion mediator activity 11/946 76/18639 0.144736842105263 2.85174418604651 0.00151069777765344 0.0391223883098666 GO:0008198 ferrous iron binding 6/946 26/18639 0.230769230769231 4.54683688404619 0.0016143382681553 0.0391223883098666 GO:0008199 ferric iron binding 4/946 11/18639 0.363636363636364 7.16471266576975 0.00163283740275377 0.0391223883098666 GO:0019864 IgG binding 4/946 11/18639 0.363636363636364 7.16471266576975 0.00163283740275377 0.0391223883098666 GO:0042608 T cell receptor binding 4/946 11/18639 0.363636363636364 7.16471266576975 0.00163283740275377 0.0391223883098666 GO:1990948 ubiquitin ligase inhibitor activity 4/946 11/18639 0.363636363636364 7.16471266576975 0.00163283740275377 0.0391223883098666 GO:0098632 cell-cell adhesion mediator activity 9/946 55/18639 0.163636363636364 3.22412069959639 0.00166639408096237 0.0391223883098666 GO:0141110 transporter inhibitor activity 8/946 45/18639 0.177777777777778 3.50274841437632 0.0017274465897722 0.0396544961607707 GO:0003779 actin binding 37/946 443/18639 0.0835214446952596 1.64561966984666 0.00209903802789484 0.0459318036714635 GO:0072341 modified amino acid binding 12/946 91/18639 0.131868131868132 2.59819250516925 0.00213199037165811 0.0459318036714635 GO:0120227 acyl-CoA binding 5/946 19/18639 0.263157894736842 5.18498942917548 0.00213429484630227 0.0459318036714635 GO:0097371 MDM2/MDM4 family protein binding 4/946 12/18639 0.333333333333333 6.5676532769556 0.00235142852031401 0.0495719522751912 GO:0004857 enzyme inhibitor activity 35/946 416/18639 0.0841346153846154 1.65770094730851 0.00242153317577709 0.0496348406249732 GO:0140375 immune receptor activity 17/946 156/18639 0.108974358974359 2.14711741746625 0.00245051004053595 0.0496348406249732 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 11/946 83/18639 0.132530120481928 2.61123564023536 0.00308845371683646 0.0613533209517704 GO:0005525 GTP binding 32/946 378/18639 0.0846560846560847 1.6679754354173 0.00330483137490065 0.0644130341560825 GO:0003714 transcription corepressor activity 20/946 204/18639 0.0980392156862745 1.93166272851635 0.00374838172968198 0.0717051541992867 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/946 41/18639 0.170731707317073 3.3639199711236 0.00420198556046993 0.0776013359248935 GO:0019001 guanyl nucleotide binding 33/946 400/18639 0.0825 1.62549418604651 0.0042819711013736 0.0776013359248935 GO:0032561 guanyl ribonucleotide binding 33/946 400/18639 0.0825 1.62549418604651 0.0042819711013736 0.0776013359248935 GO:0044548 S100 protein binding 4/946 14/18639 0.285714285714286 5.62941709453337 0.00438385628152578 0.0780779920485539 GO:0071813 lipoprotein particle binding 6/946 32/18639 0.1875 3.69430496828753 0.00490321631786761 0.0844170409392873 GO:0071814 protein-lipid complex binding 6/946 32/18639 0.1875 3.69430496828753 0.00490321631786761 0.0844170409392873 GO:0038024 cargo receptor activity 9/946 65/18639 0.138461538461538 2.72810213042771 0.00533889961731583 0.0872057172262768 GO:0008200 ion channel inhibitor activity 7/946 43/18639 0.162790697674419 3.20745857711785 0.00551728308330937 0.0872057172262768 GO:0003925 G protein activity 8/946 54/18639 0.148148148148148 2.91895701198027 0.00558355576385729 0.0872057172262768 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 8/946 54/18639 0.148148148148148 2.91895701198027 0.00558355576385729 0.0872057172262768 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/946 15/18639 0.266666666666667 5.25412262156448 0.00574055060153613 0.0872057172262768 GO:0031386 protein tag activity 4/946 15/18639 0.266666666666667 5.25412262156448 0.00574055060153613 0.0872057172262768 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/946 15/18639 0.266666666666667 5.25412262156448 0.00574055060153613 0.0872057172262768 GO:0141047 molecular tag activity 4/946 15/18639 0.266666666666667 5.25412262156448 0.00574055060153613 0.0872057172262768 GO:0004722 protein serine/threonine phosphatase activity 12/946 103/18639 0.116504854368932 2.29549046573206 0.00594765898557529 0.089042488871004 GO:0140313 molecular sequestering activity 8/946 55/18639 0.145454545454545 2.8658850663079 0.00625030668860537 0.0901017934934482 GO:0003954 NADH dehydrogenase activity 7/946 44/18639 0.159090909090909 3.13456179127426 0.00628008628415128 0.0901017934934482 GO:0016248 channel inhibitor activity 7/946 44/18639 0.159090909090909 3.13456179127426 0.00628008628415128 0.0901017934934482 GO:1901681 sulfur compound binding 24/946 275/18639 0.0872727272727273 1.71953103978474 0.00701320654305827 0.0963837301334628 GO:0008009 chemokine activity 7/946 45/18639 0.155555555555556 3.06490486257928 0.00711873043837901 0.0963837301334628 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/946 25/18639 0.2 3.94059196617336 0.0075772714286713 0.0963837301334628 GO:0033192 calmodulin-dependent protein phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0140791 histone H2AXS140 phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/946 81/18639 0.123456790123457 2.43246417665022 0.0077442880939762 0.0963837301334628 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/946 82/18639 0.121951219512195 2.402799979374 0.00843034186239505 0.102453448751225 GO:0033549 MAP kinase phosphatase activity 10/946 82/18639 0.121951219512195 2.402799979374 0.00843034186239505 0.102453448751225 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 8/946 58/18639 0.137931034482759 2.7176496318437 0.008615057187234 0.102946229523479 GO:0097110 scaffold protein binding 9/946 70/18639 0.128571428571429 2.53323769254002 0.00868083645452425 0.102946229523479 GO:0005484 SNAP receptor activity 6/946 36/18639 0.166666666666667 3.2838266384778 0.00887545324258958 0.102946229523479 GO:0004529 DNA exonuclease activity 5/946 26/18639 0.192307692307692 3.78903073670516 0.00899701741927036 0.102946229523479 GO:0019865 immunoglobulin binding 5/946 26/18639 0.192307692307692 3.78903073670516 0.00899701741927036 0.102946229523479 GO:0030169 low-density lipoprotein particle binding 4/946 17/18639 0.235294117647059 4.63599054843925 0.00923205517068836 0.102946229523479 GO:0036041 long-chain fatty acid binding 4/946 17/18639 0.235294117647059 4.63599054843925 0.00923205517068836 0.102946229523479 GO:0140789 histone phosphatase activity 14/946 136/18639 0.102941176470588 2.02824586494217 0.00926815038304312 0.102946229523479 GO:0001786 phosphatidylserine binding 8/946 59/18639 0.135593220338983 2.67158777367686 0.00953521125986622 0.10368287612044 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/946 59/18639 0.135593220338983 2.67158777367686 0.00953521125986622 0.10368287612044 GO:0017018 myosin phosphatase activity 10/946 84/18639 0.119047619047619 2.34559045605557 0.00994147046736057 0.106974364508161 GO:0004364 glutathione transferase activity 5/946 27/18639 0.185185185185185 3.64869626497533 0.0105900719554267 0.111628003366896 GO:0005044 scavenger receptor activity 5/946 27/18639 0.185185185185185 3.64869626497533 0.0105900719554267 0.111628003366896 GO:0016854 racemase and epimerase activity 4/946 18/18639 0.222222222222222 4.3784355179704 0.0114010627936342 0.118962604705294 GO:0015643 toxic substance binding 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.122287738320802 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/946 10/18639 0.3 5.91088794926004 0.0119564971639893 0.122287738320802 GO:0061135 endopeptidase regulator activity 17/946 184/18639 0.0923913043478261 1.82038215828661 0.0125800877467476 0.127404221984218 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/946 88/18639 0.113636363636364 2.23897270805305 0.0135728080773599 0.136123405280706 GO:0016830 carbon-carbon lyase activity 7/946 51/18639 0.137254901960784 2.7043278199229 0.0139831491444659 0.13889031794455 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/946 89/18639 0.112359550561798 2.21381571133335 0.0146185877690357 0.140640763313275 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/946 89/18639 0.112359550561798 2.21381571133335 0.0146185877690357 0.140640763313275 GO:0061791 GTPase motor activity 6/946 40/18639 0.15 2.95544397463002 0.014741620344155 0.140640763313275 GO:1990606 membrane scission GTPase motor activity 6/946 40/18639 0.15 2.95544397463002 0.014741620344155 0.140640763313275 GO:0019955 cytokine binding 14/946 144/18639 0.0972222222222222 1.91556553911205 0.0148401192653891 0.140640763313275 GO:0140793 histone H2AXY142 phosphatase activity 10/946 90/18639 0.111111111111111 2.1892177589852 0.015723313072632 0.147299002436123 GO:0140031 phosphorylation-dependent protein binding 3/946 11/18639 0.272727272727273 5.37353449932731 0.0158278695744527 0.147299002436123 GO:0005125 cytokine activity 20/946 234/18639 0.0854700854700855 1.68401366075785 0.0160748417447885 0.148261710021129 GO:0001530 lipopolysaccharide binding 6/946 41/18639 0.146341463414634 2.8833599752488 0.016548414878501 0.150529138983785 GO:0004721 phosphoprotein phosphatase activity 16/946 175/18639 0.0914285714285714 1.80141347025068 0.0166121218239608 0.150529138983785 GO:0005544 calcium-dependent phospholipid binding 7/946 53/18639 0.132075471698113 2.60227771351071 0.0170694469604182 0.153328162696626 GO:0033293 monocarboxylic acid binding 9/946 79/18639 0.113924050632911 2.24464099338989 0.0183913176680032 0.162378044026045 GO:0046332 SMAD binding 9/946 79/18639 0.113924050632911 2.24464099338989 0.0183913176680032 0.162378044026045 GO:0042578 phosphoric ester hydrolase activity 28/946 363/18639 0.0771349862258953 1.51978753516328 0.0185518667467981 0.162407443639342 GO:0003712 transcription coregulator activity 36/946 495/18639 0.0727272727272727 1.43294253315395 0.0194949558403729 0.169229322547102 GO:0004300 enoyl-CoA hydratase activity 3/946 12/18639 0.25 4.9257399577167 0.0203200165924989 0.174921476167094 GO:0005543 phospholipid binding 36/946 497/18639 0.0724346076458753 1.42717616481128 0.020587225030073 0.175757053355913 GO:1990841 promoter-specific chromatin binding 8/946 68/18639 0.117647058823529 2.31799527421962 0.0213848588596749 0.181070157393805 GO:0061134 peptidase regulator activity 19/946 226/18639 0.084070796460177 1.65644352560385 0.0217213200303046 0.182423769034997 GO:0016791 phosphatase activity 22/946 273/18639 0.0805860805860806 1.58778430871454 0.0221456300337246 0.184487385684174 GO:0004601 peroxidase activity 7/946 57/18639 0.12280701754386 2.41966173361522 0.0246256062673731 0.203506010193571 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/946 13/18639 0.230769230769231 4.54683688404619 0.0254376927314668 0.205290129621916 GO:0035325 Toll-like receptor binding 3/946 13/18639 0.230769230769231 4.54683688404619 0.0254376927314668 0.205290129621916 GO:0089720 caspase binding 3/946 13/18639 0.230769230769231 4.54683688404619 0.0254376927314668 0.205290129621916 GO:0004725 protein tyrosine phosphatase activity 10/946 98/18639 0.102040816326531 2.01050610519049 0.0269018520787153 0.214593311948247 GO:0004602 glutathione peroxidase activity 4/946 23/18639 0.173913043478261 3.42660170971597 0.0270059347079111 0.214593311948247 GO:0051427 hormone receptor binding 5/946 34/18639 0.147058823529412 2.89749409277453 0.0272971054740617 0.215251221028288 GO:0042379 chemokine receptor binding 8/946 72/18639 0.111111111111111 2.1892177589852 0.0290640313223254 0.227448063302743 GO:0005504 fatty acid binding 6/946 47/18639 0.127659574468085 2.51527146777023 0.0306389427738108 0.236827768493332 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.236827768493332 GO:0050699 WW domain binding 4/946 24/18639 0.166666666666667 3.2838266384778 0.0311428845602732 0.236827768493332 GO:0019763 immunoglobulin receptor activity 3/946 14/18639 0.214285714285714 4.22206282090003 0.0311796481269052 0.236827768493332 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 7/946 60/18639 0.116666666666667 2.29867864693446 0.0316101035731657 0.23834479555533 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 26/946 349/18639 0.0744985673352436 1.46784227966343 0.0329275641840535 0.24647952030527 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/946 61/18639 0.114754098360656 2.26099539042734 0.034205028772468 0.254199962028486 GO:0004866 endopeptidase inhibitor activity 14/946 161/18639 0.0869565217391304 1.71330085485798 0.0348307401015059 0.257001103748969 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/946 25/18639 0.16 3.15247357293869 0.0356315727758164 0.261045494166088 GO:0005041 low-density lipoprotein particle receptor activity 3/946 15/18639 0.2 3.94059196617336 0.0375394225082475 0.271176387769368 GO:0120283 protein serine/threonine kinase binding 3/946 15/18639 0.2 3.94059196617336 0.0375394225082475 0.271176387769368 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.28636896190425 GO:0030247 polysaccharide binding 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.28636896190425 GO:0050750 low-density lipoprotein particle receptor binding 4/946 26/18639 0.153846153846154 3.03122458936412 0.0404742192042793 0.28636896190425 GO:0004536 DNA nuclease activity 7/946 64/18639 0.109375 2.15501123150106 0.0428242415562531 0.300934976378296 GO:0005149 interleukin-1 receptor binding 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.306498429054461 GO:0005159 insulin-like growth factor receptor binding 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.306498429054461 GO:0008296 3'-5'-DNA exonuclease activity 3/946 16/18639 0.1875 3.69430496828753 0.044506064238305 0.306498429054461 GO:0030246 carbohydrate binding 21/946 280/18639 0.075 1.47772198731501 0.0482705593835073 0.330137883495998 GO:0016829 lyase activity 16/946 200/18639 0.08 1.57623678646934 0.0485778879877945 0.330137883495998 GO:0030414 peptidase inhibitor activity 14/946 169/18639 0.0828402366863905 1.63219785581145 0.0490549187353117 0.331200856559327 GO:0030331 nuclear estrogen receptor binding 5/946 40/18639 0.125 2.46286997885835 0.050453173526197 0.338257347311281 GO:0016860 intramolecular oxidoreductase activity 6/946 53/18639 0.113207547169811 2.23052375443775 0.0508932907009109 0.338257347311281 GO:0019789 SUMO transferase activity 4/946 28/18639 0.142857142857143 2.81470854726669 0.0512224343877399 0.338257347311281 GO:0004867 serine-type endopeptidase inhibitor activity 9/946 95/18639 0.0947368421052632 1.86659619450317 0.0518172148850999 0.338257347311281 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.338257347311281 GO:0070403 NAD+ binding 3/946 17/18639 0.176470588235294 3.47699291132944 0.0520647804670801 0.338257347311281 GO:0050840 extracellular matrix binding 7/946 67/18639 0.104477611940299 2.05851819128459 0.0527352519519499 0.340471970414777 GO:0031406 carboxylic acid binding 15/946 187/18639 0.0802139037433155 1.58045132333156 0.0538553810847938 0.345544153171379 GO:0051287 NAD binding 6/946 54/18639 0.111111111111111 2.1892177589852 0.0549074380876854 0.350119651509747 GO:0008201 heparin binding 14/946 172/18639 0.0813953488372093 1.60372928855893 0.0553019037835457 0.350471574284679 GO:0043236 laminin binding 4/946 29/18639 0.137931034482759 2.7176496318437 0.0571248438667933 0.359445331178194 GO:0140030 modification-dependent protein binding 14/946 173/18639 0.0809248554913295 1.59445917706437 0.0574997659657016 0.359445331178194 GO:0043177 organic acid binding 15/946 189/18639 0.0793650793650794 1.56372697070371 0.0580247093971359 0.359445331178194 GO:0019207 kinase regulator activity 21/946 287/18639 0.0731707317073171 1.4416799876244 0.0596455757487062 0.359445331178194 GO:0002039 p53 binding 7/946 69/18639 0.101449275362319 1.99885099733431 0.0600790703620707 0.359445331178194 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.359445331178194 GO:0030228 lipoprotein particle receptor activity 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.359445331178194 GO:0031690 adrenergic receptor binding 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.359445331178194 GO:0050811 GABA receptor binding 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.359445331178194 GO:0070064 proline-rich region binding 3/946 18/18639 0.166666666666667 3.2838266384778 0.0601975240017692 0.359445331178194 GO:0042626 ATPase-coupled transmembrane transporter activity 9/946 98/18639 0.0918367346938776 1.80945549467144 0.0608587636808122 0.361305188978615 GO:0022804 active transmembrane transporter activity 31/946 457/18639 0.0678336980306346 1.33652462747674 0.0620334841428026 0.366174794968658 GO:0004527 exonuclease activity 8/946 84/18639 0.0952380952380952 1.87647236484446 0.062862417521414 0.366875012992207 GO:0004860 protein kinase inhibitor activity 8/946 84/18639 0.0952380952380952 1.87647236484446 0.062862417521414 0.366875012992207 GO:0001221 transcription coregulator binding 10/946 115/18639 0.0869565217391304 1.71330085485798 0.0673417146903134 0.390808939747718 GO:0043395 heparan sulfate proteoglycan binding 3/946 19/18639 0.157894736842105 3.11099365750529 0.0688835220809279 0.39531487949777 GO:0140036 ubiquitin-modified protein reader activity 3/946 19/18639 0.157894736842105 3.11099365750529 0.0688835220809279 0.39531487949777 GO:0005164 tumor necrosis factor receptor binding 4/946 31/18639 0.129032258064516 2.5423173975312 0.0699681990524945 0.396207390385915 GO:0070325 lipoprotein particle receptor binding 4/946 31/18639 0.129032258064516 2.5423173975312 0.0699681990524945 0.396207390385915 GO:0050660 flavin adenine dinucleotide binding 8/946 86/18639 0.0930232558139535 1.83283347263877 0.0701896925853073 0.396207390385915 GO:0043014 alpha-tubulin binding 5/946 44/18639 0.113636363636364 2.23897270805305 0.0707563198727201 0.397235208850651 GO:0005518 collagen binding 7/946 72/18639 0.0972222222222222 1.91556553911205 0.0722151590247994 0.403233833906042 GO:0008408 3'-5' exonuclease activity 6/946 58/18639 0.103448275862069 2.03823722388277 0.0728253434641962 0.404454730099541 GO:0019209 kinase activator activity 12/946 148/18639 0.0810810810810811 1.5975372835838 0.0737851432562015 0.40759386622276 GO:0004197 cysteine-type endopeptidase activity 8/946 88/18639 0.0909090909090909 1.79117816644244 0.0780171415395445 0.428679293672072 GO:0048029 monosaccharide binding 7/946 74/18639 0.0945945945945946 1.86379349751443 0.0810551917724885 0.442520851157898 GO:0051020 GTPase binding 22/946 315/18639 0.0698412698412698 1.37607973421927 0.0813929929525659 0.442520851157898 GO:0030296 protein tyrosine kinase activator activity 4/946 33/18639 0.121212121212121 2.38823755525658 0.0841580029506738 0.455158204440032 GO:0002020 protease binding 11/946 136/18639 0.0808823529411765 1.59362175102599 0.0854909386835928 0.456351440921182 GO:0019210 kinase inhibitor activity 8/946 90/18639 0.0888888888888889 1.75137420718816 0.0863452427302974 0.456351440921182 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/946 21/18639 0.142857142857143 2.81470854726669 0.0878213670214437 0.456351440921182 GO:0004090 carbonyl reductase (NADPH) activity 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.456351440921182 GO:0005345 purine nucleobase transmembrane transporter activity 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.456351440921182 GO:0005381 iron ion transmembrane transporter activity 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.456351440921182 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.456351440921182 GO:0016783 sulfurtransferase activity 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.456351440921182 GO:0070513 death domain binding 2/946 10/18639 0.2 3.94059196617336 0.0883545868192027 0.456351440921182 GO:0016922 nuclear receptor binding 11/946 137/18639 0.0802919708029197 1.58198947547106 0.088933200800218 0.457054708590175 GO:0008013 beta-catenin binding 9/946 106/18639 0.0849056603773585 1.67289281582831 0.08964232402283 0.458418419384076 GO:0017022 myosin binding 7/946 76/18639 0.0921052631578947 1.81474630021142 0.0904918003180143 0.460482905066545 GO:0061133 endopeptidase activator activity 3/946 22/18639 0.136363636363636 2.68676724966366 0.0980220797137411 0.493935650459973 GO:0140035 ubiquitin-like protein reader activity 3/946 22/18639 0.136363636363636 2.68676724966366 0.0980220797137411 0.493935650459973 GO:0016763 pentosyltransferase activity 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.497323497944588 GO:0035254 glutamate receptor binding 5/946 49/18639 0.102040816326531 2.01050610519049 0.101525276364054 0.497323497944588 GO:0019902 phosphatase binding 14/946 190/18639 0.0736842105263158 1.45179704016913 0.104124659148934 0.497323497944588 GO:0010854 adenylate cyclase regulator activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0015205 nucleobase transmembrane transporter activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0015217 ADP transmembrane transporter activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0019107 myristoyltransferase activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0019206 nucleoside kinase activity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0032050 clathrin heavy chain binding 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0097493 structural molecule activity conferring elasticity 2/946 11/18639 0.181818181818182 3.58235633288487 0.104471635095814 0.497323497944588 GO:0045505 dynein intermediate chain binding 4/946 36/18639 0.111111111111111 2.1892177589852 0.107830611024263 0.507967239877592 GO:0055106 ubiquitin-protein transferase regulator activity 4/946 36/18639 0.111111111111111 2.1892177589852 0.107830611024263 0.507967239877592 GO:0032813 tumor necrosis factor receptor superfamily binding 5/946 50/18639 0.1 1.97029598308668 0.108366322131112 0.507967239877592 GO:0005158 insulin receptor binding 3/946 23/18639 0.130434782608696 2.56995128228697 0.108674501464616 0.507967239877592 GO:0005539 glycosaminoglycan binding 17/946 242/18639 0.0702479338842975 1.3840922195237 0.110136391320616 0.512481496550434 GO:0003743 translation initiation factor activity 5/946 51/18639 0.0980392156862745 1.93166272851635 0.115425825279132 0.526491274944372 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 10/946 128/18639 0.078125 1.53929373678647 0.115943183034225 0.526491274944372 GO:0019213 deacetylase activity 4/946 37/18639 0.108108108108108 2.13004971144506 0.116320010019353 0.526491274944372 GO:0140297 DNA-binding transcription factor binding 31/946 488/18639 0.0635245901639344 1.25162244827228 0.117480894269538 0.526491274944372 GO:0005178 integrin binding 12/946 161/18639 0.0745341614906832 1.46854358987827 0.11805064289936 0.526491274944372 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/946 24/18639 0.125 2.46286997885835 0.119750446736664 0.526491274944372 GO:0004622 lysophospholipase activity 3/946 24/18639 0.125 2.46286997885835 0.119750446736664 0.526491274944372 GO:0019957 C-C chemokine binding 3/946 24/18639 0.125 2.46286997885835 0.119750446736664 0.526491274944372 GO:0030215 semaphorin receptor binding 3/946 24/18639 0.125 2.46286997885835 0.119750446736664 0.526491274944372 GO:0035591 signaling adaptor activity 10/946 129/18639 0.0775193798449612 1.52736122719898 0.120331656319567 0.526491274944372 GO:0003995 acyl-CoA dehydrogenase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.526491274944372 GO:0008504 monoamine transmembrane transporter activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.526491274944372 GO:0016208 AMP binding 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.526491274944372 GO:0016840 carbon-nitrogen lyase activity 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.526491274944372 GO:0035259 nuclear glucocorticoid receptor binding 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.526491274944372 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/946 12/18639 0.166666666666667 3.2838266384778 0.121301958796477 0.526491274944372 GO:0008135 translation factor activity, RNA binding 7/946 83/18639 0.0843373493975904 1.6616954074225 0.128094204754147 0.553645663226084 GO:0017124 SH3 domain binding 9/946 115/18639 0.0782608695652174 1.54197076937219 0.130156473683717 0.555538942425876 GO:0004864 protein phosphatase inhibitor activity 5/946 53/18639 0.0943396226415094 1.85876979536479 0.130178033879011 0.555538942425876 GO:0031267 small GTPase binding 19/946 283/18639 0.0671378091872792 1.32281355754936 0.131003904264327 0.555538942425876 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.555538942425876 GO:0120020 cholesterol transfer activity 3/946 25/18639 0.12 2.36435517970402 0.13122120227678 0.555538942425876 GO:0051117 ATPase binding 7/946 84/18639 0.0833333333333333 1.6419133192389 0.134024367229851 0.557626364165079 GO:0180051 translation factor activity 7/946 84/18639 0.0833333333333333 1.6419133192389 0.134024367229851 0.557626364165079 GO:0005179 hormone activity 10/946 132/18639 0.0757575757575758 1.49264847203536 0.13403735375692 0.557626364165079 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 10/946 132/18639 0.0757575757575758 1.49264847203536 0.13403735375692 0.557626364165079 GO:0043130 ubiquitin binding 8/946 100/18639 0.08 1.57623678646934 0.135341049499519 0.557626364165079 GO:0050661 NADP binding 5/946 54/18639 0.0925925925925926 1.82434813248767 0.137858706918942 0.557626364165079 GO:0004465 lipoprotein lipase activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0004535 poly(A)-specific ribonuclease activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0005542 folic acid binding 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0008035 high-density lipoprotein particle binding 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0017154 semaphorin receptor activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0045159 myosin II binding 2/946 13/18639 0.153846153846154 3.03122458936412 0.138731825353751 0.557626364165079 GO:0019208 phosphatase regulator activity 9/946 117/18639 0.0769230769230769 1.51561229468206 0.140287959722139 0.559526881826136 GO:1990782 protein tyrosine kinase binding 9/946 117/18639 0.0769230769230769 1.51561229468206 0.140287959722139 0.559526881826136 GO:0070412 R-SMAD binding 3/946 26/18639 0.115384615384615 2.27341844202309 0.143057765286237 0.568379505925702 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/946 41/18639 0.0975609756097561 1.9222399834992 0.152970602256854 0.588461365222959 GO:0019887 protein kinase regulator activity 17/946 255/18639 0.0666666666666667 1.31353065539112 0.153166312125121 0.588461365222959 GO:0019212 phosphatase inhibitor activity 5/946 56/18639 0.0892857142857143 1.75919284204168 0.153796584399286 0.588461365222959 GO:0030170 pyridoxal phosphate binding 5/946 56/18639 0.0892857142857143 1.75919284204168 0.153796584399286 0.588461365222959 GO:0003774 cytoskeletal motor activity 11/946 153/18639 0.0718954248366013 1.41655266757866 0.155160990752997 0.588461365222959 GO:0035255 ionotropic glutamate receptor binding 3/946 27/18639 0.111111111111111 2.1892177589852 0.155231053171506 0.588461365222959 GO:0141108 transporter regulator activity 12/946 170/18639 0.0705882352941176 1.39079716453177 0.15596759264353 0.588461365222959 GO:0032182 ubiquitin-like protein binding 9/946 120/18639 0.075 1.47772198731501 0.156213824224729 0.588461365222959 GO:0005347 ATP transmembrane transporter activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0008191 metalloendopeptidase inhibitor activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0008474 palmitoyl-(protein) hydrolase activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0016530 metallochaperone activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0032036 myosin heavy chain binding 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0061665 SUMO ligase activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0098599 palmitoyl hydrolase activity 2/946 14/18639 0.142857142857143 2.81470854726669 0.156657188224892 0.588461365222959 GO:0016504 peptidase activator activity 5/946 57/18639 0.087719298245614 1.72832980972516 0.162039862315981 0.604285840333603 GO:0070279 vitamin B6 binding 5/946 57/18639 0.087719298245614 1.72832980972516 0.162039862315981 0.604285840333603 GO:0042056 chemoattractant activity 4/946 42/18639 0.0952380952380952 1.87647236484446 0.162744747292673 0.60473138112709 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 9/946 122/18639 0.0737704918032787 1.45349703670329 0.167298850048843 0.616535894343778 GO:0045499 chemorepellent activity 3/946 28/18639 0.107142857142857 2.11103141045001 0.167712087425558 0.616535894343778 GO:0097718 disordered domain specific binding 3/946 28/18639 0.107142857142857 2.11103141045001 0.167712087425558 0.616535894343778 GO:0048156 tau protein binding 4/946 43/18639 0.0930232558139535 1.83283347263877 0.172737572556067 0.629816854634861 GO:0003823 antigen binding 12/946 174/18639 0.0689655172413793 1.35882481592185 0.17461568665726 0.629816854634861 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.629816854634861 GO:0010181 FMN binding 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.629816854634861 GO:0017081 chloride channel regulator activity 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.629816854634861 GO:0051371 muscle alpha-actinin binding 2/946 15/18639 0.133333333333333 2.62706131078224 0.174982998335145 0.629816854634861 GO:0019888 protein phosphatase regulator activity 8/946 107/18639 0.0747663551401869 1.47311849202742 0.176442753878113 0.632865849847536 GO:0051015 actin filament binding 14/946 209/18639 0.0669856459330144 1.31981549106285 0.177158554293659 0.633234555658651 GO:0031593 polyubiquitin modification-dependent protein binding 5/946 59/18639 0.0847457627118644 1.66974235854803 0.179038423055633 0.633379078823523 GO:0045309 protein phosphorylated amino acid binding 5/946 59/18639 0.0847457627118644 1.66974235854803 0.179038423055633 0.633379078823523 GO:0070063 RNA polymerase binding 5/946 59/18639 0.0847457627118644 1.66974235854803 0.179038423055633 0.633379078823523 GO:0003785 actin monomer binding 3/946 29/18639 0.103448275862069 2.03823722388277 0.180472153990031 0.634107942420756 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/946 29/18639 0.103448275862069 2.03823722388277 0.180472153990031 0.634107942420756 GO:0019205 nucleobase-containing compound kinase activity 4/946 44/18639 0.0909090909090909 1.79117816644244 0.182935697824401 0.640585002890192 GO:0001098 basal transcription machinery binding 5/946 60/18639 0.0833333333333333 1.6419133192389 0.187778413871463 0.653114819963707 GO:0001099 basal RNA polymerase II transcription machinery binding 5/946 60/18639 0.0833333333333333 1.6419133192389 0.187778413871463 0.653114819963707 GO:0004620 phospholipase activity 8/946 109/18639 0.073394495412844 1.446088794926 0.189103470009209 0.655516391005078 GO:0099106 ion channel regulator activity 11/946 160/18639 0.06875 1.35457848837209 0.190333168691044 0.657572452367386 GO:0051721 protein phosphatase 2A binding 3/946 30/18639 0.1 1.97029598308668 0.193482942263643 0.660105956569294 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.660105956569294 GO:0016722 oxidoreductase activity, acting on metal ions 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.660105956569294 GO:0070411 I-SMAD binding 2/946 16/18639 0.125 2.46286997885835 0.19362256034898 0.660105956569294 GO:0019903 protein phosphatase binding 10/946 144/18639 0.0694444444444444 1.36826109936575 0.196456244109534 0.667563487385357 GO:0030276 clathrin binding 4/946 46/18639 0.0869565217391304 1.71330085485798 0.203893674287237 0.688076813232668 GO:0030291 protein serine/threonine kinase inhibitor activity 4/946 46/18639 0.0869565217391304 1.71330085485798 0.203893674287237 0.688076813232668 GO:0016853 isomerase activity 12/946 180/18639 0.0666666666666667 1.31353065539112 0.204491366565759 0.688076813232668 GO:0004550 nucleoside diphosphate kinase activity 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0016805 dipeptidase activity 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0017110 nucleoside diphosphate phosphatase activity 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0019198 transmembrane receptor protein phosphatase activity 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0031489 myosin V binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0045236 CXCR chemokine receptor binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0046965 nuclear retinoid X receptor binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0048038 quinone binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0051787 misfolded protein binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0070492 oligosaccharide binding 2/946 17/18639 0.117647058823529 2.31799527421962 0.2124969309999 0.689932926437112 GO:0001784 phosphotyrosine residue binding 4/946 47/18639 0.0851063829787234 1.67684764518015 0.214626276615235 0.689932926437112 GO:0043495 protein-membrane adaptor activity 4/946 47/18639 0.0851063829787234 1.67684764518015 0.214626276615235 0.689932926437112 GO:0004896 cytokine receptor activity 7/946 96/18639 0.0729166666666667 1.43667415433404 0.214700589421495 0.689932926437112 GO:0016298 lipase activity 9/946 130/18639 0.0692307692307692 1.36405106521386 0.215061376875847 0.689932926437112 GO:0051059 NF-kappaB binding 3/946 32/18639 0.09375 1.84715248414376 0.220146159183181 0.701885748259956 GO:0120015 sterol transfer activity 3/946 32/18639 0.09375 1.84715248414376 0.220146159183181 0.701885748259956 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/946 48/18639 0.0833333333333333 1.6419133192389 0.225509782547882 0.710414829482656 GO:0038187 pattern recognition receptor activity 4/946 48/18639 0.0833333333333333 1.6419133192389 0.225509782547882 0.710414829482656 GO:0140693 molecular condensate scaffold activity 4/946 48/18639 0.0833333333333333 1.6419133192389 0.225509782547882 0.710414829482656 GO:0008237 metallopeptidase activity 12/946 184/18639 0.0652173913043478 1.28497564114349 0.225572182062257 0.710414829482656 GO:0003713 transcription coactivator activity 16/946 256/18639 0.0625 1.23143498942918 0.229805042767524 0.714418327014225 GO:0003746 translation elongation factor activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.714418327014225 GO:0008409 5'-3' exonuclease activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.714418327014225 GO:0008525 phosphatidylcholine transporter activity 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.714418327014225 GO:0034185 apolipoprotein binding 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.714418327014225 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/946 18/18639 0.111111111111111 2.1892177589852 0.231534356874666 0.714418327014225 GO:0019842 vitamin binding 10/946 150/18639 0.0666666666666667 1.31353065539112 0.23168454941894 0.714418327014225 GO:0019843 rRNA binding 5/946 65/18639 0.0769230769230769 1.51561229468206 0.233566339264884 0.714498655571502 GO:0019956 chemokine binding 3/946 33/18639 0.0909090909090909 1.79117816644244 0.233744974806432 0.714498655571502 GO:0005201 extracellular matrix structural constituent 11/946 168/18639 0.0654761904761905 1.29007475083056 0.234477293551538 0.714498655571502 GO:0016247 channel regulator activity 11/946 168/18639 0.0654761904761905 1.29007475083056 0.234477293551538 0.714498655571502 GO:0060590 ATPase regulator activity 4/946 49/18639 0.0816326530612245 1.60840488415239 0.236530627542001 0.718635700737902 GO:0051087 protein-folding chaperone binding 9/946 134/18639 0.0671641791044776 1.32333312296867 0.24075657952503 0.729330048825091 GO:0016831 carboxy-lyase activity 3/946 34/18639 0.0882352941176471 1.73849645566472 0.24748744437342 0.739833859791575 GO:0030332 cyclin binding 3/946 34/18639 0.0882352941176471 1.73849645566472 0.24748744437342 0.739833859791575 GO:0048020 CCR chemokine receptor binding 4/946 50/18639 0.08 1.57623678646934 0.247675349751643 0.739833859791575 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.739833859791575 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.739833859791575 GO:0008301 DNA binding, bending 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.739833859791575 GO:0008381 mechanosensitive monoatomic ion channel activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.739833859791575 GO:0042577 lipid phosphatase activity 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.739833859791575 GO:0097001 ceramide binding 2/946 19/18639 0.105263157894737 2.07399577167019 0.250669749203341 0.739833859791575 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/946 67/18639 0.0746268656716418 1.47037013663185 0.252702678557328 0.743709022648775 GO:0016597 amino acid binding 4/946 51/18639 0.0784313725490196 1.54533018281308 0.258930628430155 0.759873122637357 GO:0000175 3'-5'-RNA exonuclease activity 3/946 35/18639 0.0857142857142857 1.68882512836001 0.261348743276155 0.762636304531832 GO:0061631 ubiquitin conjugating enzyme activity 3/946 35/18639 0.0857142857142857 1.68882512836001 0.261348743276155 0.762636304531832 GO:0004518 nuclease activity 13/946 209/18639 0.062200956937799 1.22554295598693 0.264482158273302 0.764938817992013 GO:0001614 purinergic nucleotide receptor activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0005326 neurotransmitter transmembrane transporter activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0010851 cyclase regulator activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0016004 phospholipase activator activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0016408 C-acyltransferase activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0016502 nucleotide receptor activity 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0030742 GTP-dependent protein binding 2/946 20/18639 0.1 1.97029598308668 0.269844193353096 0.764938817992013 GO:0005080 protein kinase C binding 4/946 52/18639 0.0769230769230769 1.51561229468206 0.270283319038804 0.764938817992013 GO:0030159 signaling receptor complex adaptor activity 4/946 52/18639 0.0769230769230769 1.51561229468206 0.270283319038804 0.764938817992013 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/946 86/18639 0.0697674418604651 1.37462510447908 0.271040348507476 0.764985464503342 GO:0051082 unfolded protein binding 8/946 121/18639 0.0661157024793388 1.30267503013995 0.272032494451939 0.765693642421942 GO:0030295 protein kinase activator activity 9/946 139/18639 0.0647482014388489 1.27573121207051 0.274270816748303 0.769896069839666 GO:1901505 carbohydrate derivative transmembrane transporter activity 4/946 53/18639 0.0754716981132075 1.48701583629183 0.281720485174297 0.787535820038074 GO:0016782 transferase activity, transferring sulphur-containing groups 5/946 70/18639 0.0714285714285714 1.40735427363334 0.282079625763879 0.787535820038074 GO:0005123 death receptor binding 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.799147081669387 GO:0019200 carbohydrate kinase activity 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.799147081669387 GO:1904047 S-adenosyl-L-methionine binding 2/946 21/18639 0.0952380952380952 1.87647236484446 0.28900449086169 0.799147081669387 GO:0042805 actinin binding 3/946 37/18639 0.0810810810810811 1.5975372835838 0.289333018919991 0.799147081669387 GO:0000149 SNARE binding 7/946 106/18639 0.0660377358490566 1.30113885675536 0.292325068126381 0.805258120998803 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/946 54/18639 0.0740740740740741 1.45947850599013 0.293229427434726 0.805601059946999 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/946 38/18639 0.0789473684210526 1.55549682875264 0.303410937073998 0.830992485983575 GO:0008374 O-acyltransferase activity 4/946 55/18639 0.0727272727272727 1.43294253315395 0.304797709349025 0.830992485983575 GO:0004407 histone deacetylase activity 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.830992485983575 GO:0008093 cytoskeletal anchor activity 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.830992485983575 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.830992485983575 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.830992485983575 GO:0033558 protein lysine deacetylase activity 2/946 22/18639 0.0909090909090909 1.79117816644244 0.308102731976485 0.830992485983575 GO:0042826 histone deacetylase binding 8/946 127/18639 0.062992125984252 1.24113132792862 0.316850103420943 0.852359783421444 GO:0000295 adenine nucleotide transmembrane transporter activity 2/946 23/18639 0.0869565217391304 1.71330085485798 0.327095896787139 0.870180134178321 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/946 23/18639 0.0869565217391304 1.71330085485798 0.327095896787139 0.870180134178321 GO:0016493 C-C chemokine receptor activity 2/946 23/18639 0.0869565217391304 1.71330085485798 0.327095896787139 0.870180134178321 GO:0004532 RNA exonuclease activity 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.870180134178321 GO:0015036 disulfide oxidoreductase activity 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.870180134178321 GO:0015144 carbohydrate transmembrane transporter activity 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.870180134178321 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.870180134178321 GO:0071855 neuropeptide receptor binding 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.870180134178321 GO:0071949 FAD binding 3/946 40/18639 0.075 1.47772198731501 0.331632963591827 0.870180134178321 GO:0044183 protein folding chaperone 5/946 75/18639 0.0666666666666667 1.31353065539112 0.33228943270478 0.870180134178321 GO:1902936 phosphatidylinositol bisphosphate binding 7/946 111/18639 0.0630630630630631 1.24252899834295 0.333305827761415 0.870180134178321 GO:0051219 phosphoprotein binding 6/946 93/18639 0.0645161290322581 1.2711586987656 0.333583091127411 0.870180134178321 GO:0140034 methylation-dependent protein binding 5/946 76/18639 0.0657894736842105 1.29624735729387 0.342447211401807 0.872339276283404 GO:0017080 sodium channel regulator activity 3/946 41/18639 0.0731707317073171 1.4416799876244 0.345737886855115 0.872339276283404 GO:0140318 protein transporter activity 3/946 41/18639 0.0731707317073171 1.4416799876244 0.345737886855115 0.872339276283404 GO:0004806 triacylglycerol lipase activity 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0015149 hexose transmembrane transporter activity 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0015295 solute:proton symporter activity 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0035035 histone acetyltransferase binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0048027 mRNA 5'-UTR binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0050431 transforming growth factor beta binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0055056 D-glucose transmembrane transporter activity 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0060229 lipase activator activity 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0070840 dynein complex binding 2/946 24/18639 0.0833333333333333 1.6419133192389 0.345945483155364 0.872339276283404 GO:0004879 nuclear receptor activity 4/946 59/18639 0.0677966101694915 1.33579388683843 0.351425927682088 0.872339276283404 GO:0015459 potassium channel regulator activity 4/946 59/18639 0.0677966101694915 1.33579388683843 0.351425927682088 0.872339276283404 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/946 60/18639 0.0666666666666667 1.31353065539112 0.363115035811419 0.872339276283404 GO:0098531 ligand-modulated transcription factor activity 4/946 60/18639 0.0666666666666667 1.31353065539112 0.363115035811419 0.872339276283404 GO:0001848 complement binding 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.872339276283404 GO:0008483 transaminase activity 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.872339276283404 GO:0017025 TBP-class protein binding 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.872339276283404 GO:0042974 nuclear retinoic acid receptor binding 2/946 25/18639 0.08 1.57623678646934 0.364617159753502 0.872339276283404 GO:0016836 hydro-lyase activity 4/946 61/18639 0.0655737704918033 1.29199736595848 0.374795501310213 0.872339276283404 GO:0019905 syntaxin binding 4/946 61/18639 0.0655737704918033 1.29199736595848 0.374795501310213 0.872339276283404 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 13/946 229/18639 0.0567685589519651 1.11850863668676 0.379491912086761 0.872339276283404 GO:0005506 iron ion binding 9/946 154/18639 0.0584415584415584 1.15147167842728 0.380950521002925 0.872339276283404 GO:0001637 G protein-coupled chemoattractant receptor activity 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0004950 chemokine receptor activity 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0005112 Notch binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0005160 transforming growth factor beta receptor binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0015145 monosaccharide transmembrane transporter activity 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0015216 purine nucleotide transmembrane transporter activity 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0030507 spectrin binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0043548 phosphatidylinositol 3-kinase binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0050681 nuclear androgen receptor binding 2/946 26/18639 0.0769230769230769 1.51561229468206 0.383080442625775 0.872339276283404 GO:0000287 magnesium ion binding 13/946 230/18639 0.0565217391304348 1.11364555565769 0.385451739883138 0.872339276283404 GO:0001046 core promoter sequence-specific DNA binding 3/946 44/18639 0.0681818181818182 1.34338362483183 0.38781401135217 0.872339276283404 GO:0001223 transcription coactivator binding 3/946 44/18639 0.0681818181818182 1.34338362483183 0.38781401135217 0.872339276283404 GO:0016790 thiolester hydrolase activity 3/946 44/18639 0.0681818181818182 1.34338362483183 0.38781401135217 0.872339276283404 GO:0030547 signaling receptor inhibitor activity 3/946 44/18639 0.0681818181818182 1.34338362483183 0.38781401135217 0.872339276283404 GO:0001618 virus receptor activity 5/946 81/18639 0.0617283950617284 1.21623208832511 0.393403722309787 0.872339276283404 GO:0030971 receptor tyrosine kinase binding 5/946 81/18639 0.0617283950617284 1.21623208832511 0.393403722309787 0.872339276283404 GO:0001671 ATPase activator activity 2/946 27/18639 0.0740740740740741 1.45947850599013 0.401308393782115 0.872339276283404 GO:0015252 proton channel activity 2/946 27/18639 0.0740740740740741 1.45947850599013 0.401308393782115 0.872339276283404 GO:0046915 transition metal ion transmembrane transporter activity 3/946 45/18639 0.0666666666666667 1.31353065539112 0.401706040662631 0.872339276283404 GO:0140272 exogenous protein binding 5/946 82/18639 0.0609756097560976 1.201399989687 0.403579569039444 0.872339276283404 GO:0001094 TFIID-class transcription factor complex binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0003796 lysozyme activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0004382 GDP phosphatase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0004935 adrenergic receptor activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0004955 prostaglandin receptor activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0005337 nucleoside transmembrane transporter activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0005522 profilin binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0008239 dipeptidyl-peptidase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0015279 store-operated calcium channel activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0016868 intramolecular phosphotransferase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0019911 structural constituent of myelin sheath 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0030957 Tat protein binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0035256 G protein-coupled glutamate receptor binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0042166 acetylcholine binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0043208 glycosphingolipid binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0043295 glutathione binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0043422 protein kinase B binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0047429 nucleoside triphosphate diphosphatase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0050308 sugar-phosphatase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0050815 phosphoserine residue binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0070097 delta-catenin binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0097177 mitochondrial ribosome binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0098505 G-rich strand telomeric DNA binding 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0140999 histone H3K4 trimethyltransferase activity 1/946 10/18639 0.1 1.97029598308668 0.40607362633771 0.872339276283404 GO:0004180 carboxypeptidase activity 3/946 46/18639 0.0652173913043478 1.28497564114349 0.415506903433007 0.872339276283404 GO:0008238 exopeptidase activity 6/946 102/18639 0.0588235294117647 1.15899763710981 0.415885467379801 0.872339276283404 GO:0046625 sphingolipid binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0046875 ephrin receptor binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0051019 mitogen-activated protein kinase binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0051119 sugar transmembrane transporter activity 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0051393 alpha-actinin binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0051537 2 iron, 2 sulfur cluster binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0051959 dynein light intermediate chain binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/946 28/18639 0.0714285714285714 1.40735427363334 0.419277340424928 0.872339276283404 GO:0120013 lipid transfer activity 4/946 65/18639 0.0615384615384615 1.21248983574565 0.42123489306475 0.872339276283404 GO:0160215 deacylase activity 4/946 65/18639 0.0615384615384615 1.21248983574565 0.42123489306475 0.872339276283404 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0001851 complement component C3b binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0004954 prostanoid receptor activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0005114 type II transforming growth factor beta receptor binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0005536 D-glucose binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0008432 JUN kinase binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0008526 phosphatidylinositol transfer activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0019203 carbohydrate phosphatase activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0019215 intermediate filament binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0031731 CCR6 chemokine receptor binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0032404 mismatch repair complex binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0032794 GTPase activating protein binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0034056 estrogen response element binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0045294 alpha-catenin binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0048185 activin binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0050786 RAGE receptor binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0050998 nitric-oxide synthase binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0140537 transcription regulator activator activity 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:1900750 oligopeptide binding 1/946 11/18639 0.0909090909090909 1.79117816644244 0.436233825461899 0.872339276283404 GO:0035250 UDP-galactosyltransferase activity 2/946 29/18639 0.0689655172413793 1.35882481592185 0.436966613494179 0.872339276283404 GO:0051861 glycolipid binding 2/946 29/18639 0.0689655172413793 1.35882481592185 0.436966613494179 0.872339276283404 GO:0106222 lncRNA binding 2/946 29/18639 0.0689655172413793 1.35882481592185 0.436966613494179 0.872339276283404 GO:0001664 G protein-coupled receptor binding 16/946 297/18639 0.0538720538720539 1.06143891344737 0.439671835565454 0.872339276283404 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/946 48/18639 0.0625 1.23143498942918 0.442782878290883 0.872339276283404 GO:0008081 phosphoric diester hydrolase activity 5/946 87/18639 0.0574712643678161 1.13235401326821 0.454027549169232 0.872339276283404 GO:0001965 G-protein alpha-subunit binding 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0001968 fibronectin binding 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0015215 nucleotide transmembrane transporter activity 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0016769 transferase activity, transferring nitrogenous groups 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0031624 ubiquitin conjugating enzyme binding 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0048019 receptor antagonist activity 2/946 30/18639 0.0666666666666667 1.31353065539112 0.45435830429636 0.872339276283404 GO:0032934 sterol binding 4/946 68/18639 0.0588235294117647 1.15899763710981 0.455517767340551 0.872339276283404 GO:0001222 transcription corepressor binding 3/946 49/18639 0.0612244897959184 1.20630366311429 0.456234112035376 0.872339276283404 GO:0004000 adenosine deaminase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0004875 complement receptor activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0005025 transforming growth factor beta receptor activity, type I 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0005026 transforming growth factor beta receptor activity, type II 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0005078 MAP-kinase scaffold activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0005165 neurotrophin receptor binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0005247 voltage-gated chloride channel activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0008179 adenylate cyclase binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0008603 cAMP-dependent protein kinase regulator activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0010853 cyclase activator activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0015132 prostaglandin transmembrane transporter activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0016361 activin receptor activity, type I 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0016362 activin receptor activity, type II 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0016801 hydrolase activity, acting on ether bonds 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0016803 ether hydrolase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0017002 activin receptor activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0031543 peptidyl-proline dioxygenase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0042301 phosphate ion binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0043047 single-stranded telomeric DNA binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0070008 serine-type exopeptidase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0070410 co-SMAD binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0097677 STAT family protein binding 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/946 12/18639 0.0833333333333333 1.6419133192389 0.464863995158756 0.872339276283404 GO:1901981 phosphatidylinositol phosphate binding 10/946 185/18639 0.0540540540540541 1.06502485572253 0.465303912131806 0.872339276283404 GO:0005496 steroid binding 6/946 108/18639 0.0555555555555556 1.0946088794926 0.470256381576064 0.877467496061369 GO:0016411 acylglycerol O-acyltransferase activity 2/946 31/18639 0.0645161290322581 1.2711586987656 0.471437038058141 0.877467496061369 GO:0016878 acid-thiol ligase activity 2/946 31/18639 0.0645161290322581 1.2711586987656 0.471437038058141 0.877467496061369 GO:0047499 calcium-independent phospholipase A2 activity 2/946 31/18639 0.0645161290322581 1.2711586987656 0.471437038058141 0.877467496061369 GO:0008234 cysteine-type peptidase activity 10/946 187/18639 0.053475935828877 1.05363421555437 0.478950777506511 0.887048955118746 GO:0005516 calmodulin binding 11/946 207/18639 0.0531400966183575 1.04701718907988 0.481952662739843 0.887048955118746 GO:0008378 galactosyltransferase activity 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.887048955118746 GO:0043425 bHLH transcription factor binding 2/946 32/18639 0.0625 1.23143498942918 0.488189763316471 0.887048955118746 GO:0015631 tubulin binding 20/946 385/18639 0.051948051948052 1.02353038082425 0.490236996178384 0.887048955118746 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/946 130/18639 0.0538461538461538 1.06092860627744 0.491584198226195 0.887048955118746 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0019855 calcium channel inhibitor activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0031432 titin binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0035673 oligopeptide transmembrane transporter activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0046975 histone H3K36 methyltransferase activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0061459 L-arginine transmembrane transporter activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0070123 transforming growth factor beta receptor activity, type III 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0071714 icosanoid transmembrane transporter activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0097157 pre-mRNA intronic binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0140666 annealing activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:1901338 catecholamine binding 1/946 13/18639 0.0769230769230769 1.51561229468206 0.492041675975839 0.887048955118746 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/946 52/18639 0.0576923076923077 1.13670922101155 0.495715563959711 0.892115291934462 GO:0031072 heat shock protein binding 7/946 131/18639 0.0534351145038168 1.05282991462647 0.499718726716908 0.895368377151875 GO:0052689 carboxylic ester hydrolase activity 5/946 92/18639 0.0543478260869565 1.07081303428624 0.503241093435695 0.895368377151875 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/946 33/18639 0.0606060606060606 1.19411877762829 0.50460555612357 0.895368377151875 GO:0071889 14-3-3 protein binding 2/946 33/18639 0.0606060606060606 1.19411877762829 0.50460555612357 0.895368377151875 GO:0140416 transcription regulator inhibitor activity 2/946 33/18639 0.0606060606060606 1.19411877762829 0.50460555612357 0.895368377151875 GO:0008146 sulfotransferase activity 3/946 53/18639 0.0566037735849057 1.11526187721888 0.508555268686835 0.895368377151875 GO:0034212 protein N-acetyltransferase activity 3/946 53/18639 0.0566037735849057 1.11526187721888 0.508555268686835 0.895368377151875 GO:0140296 general transcription initiation factor binding 3/946 53/18639 0.0566037735849057 1.11526187721888 0.508555268686835 0.895368377151875 GO:0043539 protein serine/threonine kinase activator activity 4/946 73/18639 0.0547945205479452 1.07961423730777 0.511001652223468 0.895368377151875 GO:0005096 GTPase activator activity 14/946 271/18639 0.0516605166051661 1.01786508351341 0.511983974504568 0.895368377151875 GO:0051213 dioxygenase activity 5/946 93/18639 0.0537634408602151 1.059298915638 0.512880752657757 0.895368377151875 GO:0005545 1-phosphatidylinositol binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0008195 phosphatidate phosphatase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0015926 glucosidase activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0042043 neurexin family protein binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0061783 peptidoglycan muralytic activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0071933 Arp2/3 complex binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0098821 BMP receptor activity 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0098847 sequence-specific single stranded DNA binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:1901612 cardiolipin binding 1/946 14/18639 0.0714285714285714 1.40735427363334 0.517840482725912 0.895368377151875 GO:0008376 acetylgalactosaminyltransferase activity 2/946 34/18639 0.0588235294117647 1.15899763710981 0.520675438107954 0.895368377151875 GO:0090482 vitamin transmembrane transporter activity 2/946 34/18639 0.0588235294117647 1.15899763710981 0.520675438107954 0.895368377151875 GO:0015485 cholesterol binding 3/946 54/18639 0.0555555555555556 1.0946088794926 0.521221494642842 0.895368377151875 GO:0003684 damaged DNA binding 4/946 74/18639 0.0540540540540541 1.06502485572253 0.521792607013968 0.895368377151875 GO:0031491 nucleosome binding 4/946 74/18639 0.0540540540540541 1.06502485572253 0.521792607013968 0.895368377151875 GO:0035064 methylated histone binding 4/946 74/18639 0.0540540540540541 1.06502485572253 0.521792607013968 0.895368377151875 GO:0004623 phospholipase A2 activity 2/946 35/18639 0.0571428571428571 1.12588341890667 0.5363922074917 0.901841550215502 GO:0005154 epidermal growth factor receptor binding 2/946 35/18639 0.0571428571428571 1.12588341890667 0.5363922074917 0.901841550215502 GO:0044325 transmembrane transporter binding 7/946 136/18639 0.0514705882352941 1.01412293247109 0.539707273088068 0.901841550215502 GO:0000774 adenyl-nucleotide exchange factor activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0004953 icosanoid receptor activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0005523 tropomyosin binding 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0015929 hexosaminidase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0016846 carbon-sulfur lyase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0030553 cGMP binding 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0033130 acetylcholine receptor binding 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0047372 monoacylglycerol lipase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0048531 beta-1,3-galactosyltransferase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0050700 CARD domain binding 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0061578 K63-linked deubiquitinase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0140776 protein-containing complex destabilizing activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0141050 histone H3K deacetylase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0141051 histone H4K deacetylase activity 1/946 15/18639 0.0666666666666667 1.31353065539112 0.542330303039539 0.901841550215502 GO:0051536 iron-sulfur cluster binding 4/946 76/18639 0.0526315789473684 1.0369978858351 0.543025599452122 0.901841550215502 GO:0170055 lipid transmembrane transporter activity 3/946 56/18639 0.0535714285714286 1.05551570522501 0.546007159713886 0.905337714260746 GO:0000993 RNA polymerase II complex binding 2/946 36/18639 0.0555555555555556 1.0946088794926 0.55175028221961 0.907576499256141 GO:0004033 aldo-keto reductase (NADPH) activity 2/946 36/18639 0.0555555555555556 1.0946088794926 0.55175028221961 0.907576499256141 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/946 36/18639 0.0555555555555556 1.0946088794926 0.55175028221961 0.907576499256141 GO:0016409 palmitoyltransferase activity 2/946 36/18639 0.0555555555555556 1.0946088794926 0.55175028221961 0.907576499256141 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/946 36/18639 0.0555555555555556 1.0946088794926 0.55175028221961 0.907576499256141 GO:0051540 metal cluster binding 4/946 77/18639 0.051948051948052 1.02353038082425 0.553458466056952 0.908938943460782 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/946 57/18639 0.0526315789473684 1.0369978858351 0.558115113199899 0.91145326508549 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0005024 transforming growth factor beta receptor activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0008142 oxysterol binding 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0015378 sodium:chloride symporter activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0034450 ubiquitin-ubiquitin ligase activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0043023 ribosomal large subunit binding 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0140328 floppase activity 1/946 16/18639 0.0625 1.23143498942918 0.565577485885575 0.91145326508549 GO:0016835 carbon-oxygen lyase activity 4/946 79/18639 0.0506329113924051 0.997618219284395 0.573936553206097 0.918362036678678 GO:0000146 microfilament motor activity 2/946 38/18639 0.0526315789473684 1.0369978858351 0.581375255371169 0.918362036678678 GO:0042887 amide transmembrane transporter activity 2/946 38/18639 0.0526315789473684 1.0369978858351 0.581375255371169 0.918362036678678 GO:0043531 ADP binding 2/946 38/18639 0.0526315789473684 1.0369978858351 0.581375255371169 0.918362036678678 GO:0003697 single-stranded DNA binding 6/946 121/18639 0.0495867768595041 0.977006272604966 0.581969675956362 0.918362036678678 GO:0004540 RNA nuclease activity 6/946 121/18639 0.0495867768595041 0.977006272604966 0.581969675956362 0.918362036678678 GO:0008083 growth factor activity 8/946 162/18639 0.0493827160493827 0.972985670660089 0.582627542367169 0.918362036678678 GO:0035091 phosphatidylinositol binding 14/946 284/18639 0.0492957746478873 0.971272667718786 0.583605903902403 0.918362036678678 GO:0020037 heme binding 7/946 142/18639 0.0492957746478873 0.971272667718786 0.585867852748339 0.918362036678678 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0004549 tRNA-specific ribonuclease activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0005092 GDP-dissociation inhibitor activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0030548 acetylcholine receptor regulator activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0032183 SUMO binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0032977 membrane insertase activity 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0038191 neuropilin binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0070402 NADPH binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:1990226 histone methyltransferase binding 1/946 17/18639 0.0588235294117647 1.15899763710981 0.58764502056593 0.918362036678678 GO:0015101 organic cation transmembrane transporter activity 4/946 81/18639 0.0493827160493827 0.972985670660089 0.59387438431507 0.926647408031059 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/946 39/18639 0.0512820512820513 1.01040819645471 0.595637830525289 0.926647408031059 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/946 39/18639 0.0512820512820513 1.01040819645471 0.595637830525289 0.926647408031059 GO:0015026 coreceptor activity 3/946 61/18639 0.0491803278688525 0.968998024468859 0.604542787333201 0.928683490705023 GO:0000900 mRNA regulatory element binding translation repressor activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0008308 voltage-gated monoatomic anion channel activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0015373 monoatomic anion:sodium symporter activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0017075 syntaxin-1 binding 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0035615 clathrin adaptor activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0070628 proteasome binding 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0099602 neurotransmitter receptor regulator activity 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:1901611 phosphatidylglycerol binding 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:1990381 ubiquitin-specific protease binding 1/946 18/18639 0.0555555555555556 1.0946088794926 0.608592706665416 0.928683490705023 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/946 40/18639 0.05 0.98514799154334 0.609532823521787 0.928683490705023 GO:0140662 ATP-dependent protein folding chaperone 2/946 40/18639 0.05 0.98514799154334 0.609532823521787 0.928683490705023 GO:0016874 ligase activity 8/946 167/18639 0.0479041916167665 0.943854363155296 0.617145463438141 0.938174952054839 GO:0001727 lipid kinase activity 2/946 41/18639 0.0487804878048781 0.9611199917496 0.623060768991872 0.938174952054839 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/946 41/18639 0.0487804878048781 0.9611199917496 0.623060768991872 0.938174952054839 GO:0008227 G protein-coupled amine receptor activity 2/946 41/18639 0.0487804878048781 0.9611199917496 0.623060768991872 0.938174952054839 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/946 41/18639 0.0487804878048781 0.9611199917496 0.623060768991872 0.938174952054839 GO:0042169 SH2 domain binding 2/946 41/18639 0.0487804878048781 0.9611199917496 0.623060768991872 0.938174952054839 GO:0042287 MHC protein binding 2/946 41/18639 0.0487804878048781 0.9611199917496 0.623060768991872 0.938174952054839 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:0015245 fatty acid transmembrane transporter activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:0030506 ankyrin binding 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:0042800 histone H3K4 methyltransferase activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:0042834 peptidoglycan binding 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:0070003 threonine-type peptidase activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:1990380 K48-linked deubiquitinase activity 1/946 19/18639 0.0526315789473684 1.0369978858351 0.628477315413309 0.938174952054839 GO:0004402 histone acetyltransferase activity 2/946 42/18639 0.0476190476190476 0.938236182422229 0.636223093331162 0.942924613215338 GO:0004520 DNA endonuclease activity 2/946 42/18639 0.0476190476190476 0.938236182422229 0.636223093331162 0.942924613215338 GO:0008307 structural constituent of muscle 2/946 42/18639 0.0476190476190476 0.938236182422229 0.636223093331162 0.942924613215338 GO:0019894 kinesin binding 2/946 42/18639 0.0476190476190476 0.938236182422229 0.636223093331162 0.942924613215338 GO:0043175 RNA polymerase core enzyme binding 2/946 42/18639 0.0476190476190476 0.938236182422229 0.636223093331162 0.942924613215338 GO:0001972 retinoic acid binding 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.951230986352117 GO:0015464 acetylcholine receptor activity 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.951230986352117 GO:0031418 L-ascorbic acid binding 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.951230986352117 GO:0042288 MHC class I protein binding 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.951230986352117 GO:0043024 ribosomal small subunit binding 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.951230986352117 GO:0061608 nuclear import signal receptor activity 1/946 20/18639 0.05 0.98514799154334 0.647352742890163 0.951230986352117 GO:0008375 acetylglucosaminyltransferase activity 2/946 43/18639 0.0465116279069767 0.916416736319386 0.649022022984886 0.952329189976403 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/946 130/18639 0.0461538461538462 0.909367376809237 0.651756525709838 0.954985093699663 GO:0046906 tetrapyrrole binding 7/946 152/18639 0.0460526315789474 0.907373150105708 0.657301348237329 0.957136588611154 GO:0008235 metalloexopeptidase activity 3/946 66/18639 0.0454545454545455 0.895589083221219 0.657853934299939 0.957136588611154 GO:0004222 metalloendopeptidase activity 5/946 110/18639 0.0454545454545455 0.895589083221219 0.662250594369849 0.957136588611154 GO:0001846 opsonin binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0010314 phosphatidylinositol-5-phosphate binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0015174 basic amino acid transmembrane transporter activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0035613 RNA stem-loop binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0051010 microtubule plus-end binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0051428 peptide hormone receptor binding 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0061891 calcium ion sensor activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0072542 protein phosphatase activator activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0140312 cargo adaptor activity 1/946 21/18639 0.0476190476190476 0.938236182422229 0.665270155491586 0.957136588611154 GO:0051539 4 iron, 4 sulfur cluster binding 2/946 45/18639 0.0444444444444444 0.87568710359408 0.673542102476589 0.965824265712514 GO:0030695 GTPase regulator activity 23/946 489/18639 0.0470347648261759 0.92672408202441 0.677587018579356 0.965824265712514 GO:0003777 microtubule motor activity 3/946 68/18639 0.0441176470588235 0.869248227832359 0.67767181216172 0.965824265712514 GO:0060589 nucleoside-triphosphatase regulator activity 23/946 490/18639 0.0469387755102041 0.924832808387626 0.681319556992977 0.965824265712514 GO:0008970 phospholipase A1 activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0015377 chloride:monoatomic cation symporter activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0016881 acid-amino acid ligase activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0031683 G-protein beta/gamma-subunit complex binding 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0070034 telomerase RNA binding 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0140517 protein-RNA adaptor activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0140784 metal ion sensor activity 1/946 22/18639 0.0454545454545455 0.895589083221219 0.682278128039924 0.965824265712514 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/946 91/18639 0.043956043956044 0.86606416838975 0.684784004495175 0.965824265712514 GO:0001216 DNA-binding transcription activator activity 23/946 491/18639 0.0468431771894094 0.922949238513109 0.685028808272554 0.965824265712514 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/946 46/18639 0.0434782608695652 0.856650427428992 0.685270975160388 0.965824265712514 GO:0008080 N-acetyltransferase activity 3/946 69/18639 0.0434782608695652 0.856650427428992 0.687256970600605 0.965824265712514 GO:0019838 growth factor binding 6/946 136/18639 0.0441176470588235 0.869248227832359 0.694090533229173 0.965824265712514 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/946 70/18639 0.0428571428571429 0.844412564180006 0.696626981256818 0.965824265712514 GO:0061733 protein-lysine-acetyltransferase activity 2/946 47/18639 0.0425531914893617 0.838423822590077 0.696651760287207 0.965824265712514 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0005212 structural constituent of eye lens 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0016849 phosphorus-oxygen lyase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0031681 G-protein beta-subunit binding 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0042171 lysophosphatidic acid acyltransferase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0070577 lysine-acetylated histone binding 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0071617 lysophospholipid acyltransferase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0140102 catalytic activity, acting on a rRNA 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0140103 catalytic activity, acting on a glycoprotein 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/946 23/18639 0.0434782608695652 0.856650427428992 0.698422774915051 0.965824265712514 GO:0032266 phosphatidylinositol-3-phosphate binding 2/946 48/18639 0.0416666666666667 0.82095665961945 0.707689537765308 0.974684783422182 GO:0016410 N-acyltransferase activity 4/946 94/18639 0.0425531914893617 0.838423822590077 0.709074606870667 0.974684783422182 GO:0042562 hormone binding 4/946 94/18639 0.0425531914893617 0.838423822590077 0.709074606870667 0.974684783422182 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.974684783422182 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.974684783422182 GO:0005540 hyaluronic acid binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.974684783422182 GO:0030552 cAMP binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.974684783422182 GO:0070300 phosphatidic acid binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.974684783422182 GO:0140033 acetylation-dependent protein binding 1/946 24/18639 0.0416666666666667 0.82095665961945 0.713747874556776 0.974684783422182 GO:0042393 histone binding 11/946 247/18639 0.0445344129554656 0.877459749552773 0.714265615731454 0.974684783422182 GO:0016407 acetyltransferase activity 4/946 96/18639 0.0416666666666667 0.82095665961945 0.724493870910969 0.9789431280634 GO:0003707 nuclear steroid receptor activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0004709 MAP kinase kinase kinase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0008139 nuclear localization sequence binding 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0015645 fatty acid ligase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0017056 structural constituent of nuclear pore 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0019211 phosphatase activator activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0019707 protein-cysteine S-acyltransferase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0120515 fatty acid-CoA ligase activity 1/946 25/18639 0.04 0.788118393234672 0.72829498767358 0.9789431280634 GO:0015605 organophosphate ester transmembrane transporter activity 2/946 50/18639 0.04 0.788118393234672 0.728758243447004 0.9789431280634 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 22/946 484/18639 0.0454545454545455 0.895589083221219 0.734139319881726 0.980297937683099 GO:0005085 guanyl-nucleotide exchange factor activity 10/946 230/18639 0.0434782608695652 0.856650427428992 0.736059852329576 0.980297937683099 GO:0005021 vascular endothelial growth factor receptor activity 2/946 51/18639 0.0392156862745098 0.772665091406541 0.73880103470925 0.980297937683099 GO:0030544 Hsp70 protein binding 2/946 51/18639 0.0392156862745098 0.772665091406541 0.73880103470925 0.980297937683099 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0004435 phosphatidylinositol phospholipase C activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0008143 poly(A) binding 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0008157 protein phosphatase 1 binding 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0034237 protein kinase A regulatory subunit binding 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0051139 metal cation:proton antiporter activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0052742 phosphatidylinositol kinase activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0097602 cullin family protein binding 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:0120014 phospholipid transfer activity 1/946 26/18639 0.0384615384615385 0.757806147341031 0.742103569475492 0.980297937683099 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/946 122/18639 0.040983606557377 0.807498353724049 0.747855018352203 0.986633759843966 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.987322654642643 GO:0008266 poly(U) RNA binding 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.987322654642643 GO:0008320 protein transmembrane transporter activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.987322654642643 GO:0008395 steroid hydroxylase activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.987322654642643 GO:0016405 CoA-ligase activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.987322654642643 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/946 27/18639 0.037037037037037 0.729739252995067 0.755211076232929 0.987322654642643 GO:0005246 calcium channel regulator activity 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.987322654642643 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.987322654642643 GO:0017046 peptide hormone binding 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.987322654642643 GO:0051018 protein kinase A binding 2/946 53/18639 0.0377358490566038 0.743507918145917 0.757935009807953 0.987322654642643 GO:0019199 transmembrane receptor protein kinase activity 3/946 78/18639 0.0384615384615385 0.757806147341031 0.76400145812848 0.993716312833115 GO:0016866 intramolecular transferase activity 1/946 28/18639 0.0357142857142857 0.703677136816672 0.76765306644804 0.993716312833115 GO:0036408 histone H3K14 acetyltransferase activity 1/946 28/18639 0.0357142857142857 0.703677136816672 0.76765306644804 0.993716312833115 GO:0046966 nuclear thyroid hormone receptor binding 1/946 28/18639 0.0357142857142857 0.703677136816672 0.76765306644804 0.993716312833115 GO:0050698 proteoglycan sulfotransferase activity 1/946 28/18639 0.0357142857142857 0.703677136816672 0.76765306644804 0.993716312833115 GO:0000049 tRNA binding 3/946 80/18639 0.0375 0.738860993657505 0.778810361267274 0.99996521761986 GO:0004181 metallocarboxypeptidase activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.99996521761986 GO:0004629 phospholipase C activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.99996521761986 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.99996521761986 GO:0010484 histone H3 acetyltransferase activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.99996521761986 GO:0016417 S-acyltransferase activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.99996521761986 GO:0097472 cyclin-dependent protein kinase activity 1/946 29/18639 0.0344827586206897 0.679412407960924 0.779463296910678 0.99996521761986 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/946 56/18639 0.0357142857142857 0.703677136816672 0.784356841525945 0.99996521761986 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0008187 poly-pyrimidine tract binding 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0031210 phosphatidylcholine binding 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0033612 receptor serine/threonine kinase binding 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0043995 histone H4K5 acetyltransferase activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0043996 histone H4K8 acetyltransferase activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0043997 histone H4K12 acetyltransferase activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0070566 adenylyltransferase activity 1/946 30/18639 0.0333333333333333 0.65676532769556 0.790673813897379 0.99996521761986 GO:0005254 chloride channel activity 3/946 83/18639 0.036144578313253 0.712155174609644 0.799580601973618 0.99996521761986 GO:0030165 PDZ domain binding 3/946 83/18639 0.036144578313253 0.712155174609644 0.799580601973618 0.99996521761986 GO:0005262 calcium channel activity 5/946 131/18639 0.0381679389312977 0.752021367590336 0.800707498061486 0.99996521761986 GO:0005184 neuropeptide hormone activity 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.99996521761986 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.99996521761986 GO:0008327 methyl-CpG binding 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.99996521761986 GO:0017147 Wnt-protein binding 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.99996521761986 GO:0070273 phosphatidylinositol-4-phosphate binding 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.99996521761986 GO:0072349 modified amino acid transmembrane transporter activity 1/946 31/18639 0.032258064516129 0.6355793493828 0.801315039758687 0.99996521761986 GO:0016757 glycosyltransferase activity 11/946 267/18639 0.0411985018726592 0.811732427488895 0.801466217510277 0.99996521761986 GO:0036002 pre-mRNA binding 2/946 59/18639 0.0338983050847458 0.667896943419214 0.808209303802081 0.99996521761986 GO:0008514 organic anion transmembrane transporter activity 11/946 269/18639 0.0408921933085502 0.805697242154405 0.80899389196519 0.99996521761986 GO:0022884 macromolecule transmembrane transporter activity 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0030515 snoRNA binding 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0031369 translation initiation factor binding 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0047498 calcium-dependent phospholipase A2 activity 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0070717 poly-purine tract binding 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0140142 nucleocytoplasmic carrier activity 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0160041 neuropeptide activity 1/946 32/18639 0.03125 0.615717494714588 0.811415855127791 0.99996521761986 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/946 60/18639 0.0333333333333333 0.65676532769556 0.81562190943389 0.99996521761986 GO:0019239 deaminase activity 1/946 33/18639 0.0303030303030303 0.597059388814146 0.821003676971672 0.99996521761986 GO:0005200 structural constituent of cytoskeleton 4/946 112/18639 0.0357142857142857 0.703677136816672 0.826386316113001 0.99996521761986 GO:0015035 protein-disulfide reductase activity 1/946 34/18639 0.0294117647058824 0.579498818554906 0.830104532694815 0.99996521761986 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/946 34/18639 0.0294117647058824 0.579498818554906 0.830104532694815 0.99996521761986 GO:1901682 sulfur compound transmembrane transporter activity 2/946 63/18639 0.0317460317460317 0.625490788281486 0.836343386246702 0.99996521761986 GO:0005343 organic acid:sodium symporter activity 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.99996521761986 GO:0010485 histone H4 acetyltransferase activity 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.99996521761986 GO:0016229 steroid dehydrogenase activity 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.99996521761986 GO:0043015 gamma-tubulin binding 1/946 35/18639 0.0285714285714286 0.562941709453337 0.838743130494907 0.99996521761986 GO:0070851 growth factor receptor binding 5/946 139/18639 0.0359712230215827 0.708739562261396 0.839982907712105 0.99996521761986 GO:0140767 enzyme-substrate adaptor activity 5/946 139/18639 0.0359712230215827 0.708739562261396 0.839982907712105 0.99996521761986 GO:0001217 DNA-binding transcription repressor activity 11/946 278/18639 0.039568345323741 0.779613518487536 0.840261527768394 0.99996521761986 GO:0101005 deubiquitinase activity 4/946 115/18639 0.0347826086956522 0.685320341943193 0.841534617940262 0.99996521761986 GO:0015294 solute:monoatomic cation symporter activity 4/946 116/18639 0.0344827586206897 0.679412407960924 0.84633100598447 0.99996521761986 GO:0004190 aspartic-type endopeptidase activity 1/946 36/18639 0.0277777777777778 0.5473044397463 0.846942926159916 0.99996521761986 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/946 36/18639 0.0277777777777778 0.5473044397463 0.846942926159916 0.99996521761986 GO:0043178 alcohol binding 3/946 92/18639 0.0326086956521739 0.642487820571744 0.852285709560879 0.99996521761986 GO:0030280 structural constituent of skin epidermis 1/946 37/18639 0.027027027027027 0.532512427861265 0.854726186486353 0.99996521761986 GO:0030551 cyclic nucleotide binding 1/946 37/18639 0.027027027027027 0.532512427861265 0.854726186486353 0.99996521761986 GO:0070001 aspartic-type peptidase activity 1/946 37/18639 0.027027027027027 0.532512427861265 0.854726186486353 0.99996521761986 GO:0016500 protein-hormone receptor activity 2/946 67/18639 0.0298507462686567 0.588148054652741 0.860691417506978 0.99996521761986 GO:0005501 retinoid binding 1/946 38/18639 0.0263157894736842 0.518498942917548 0.862114049489466 0.99996521761986 GO:0019840 isoprenoid binding 1/946 38/18639 0.0263157894736842 0.518498942917548 0.862114049489466 0.99996521761986 GO:0042162 telomeric DNA binding 1/946 38/18639 0.0263157894736842 0.518498942917548 0.862114049489466 0.99996521761986 GO:0008194 UDP-glycosyltransferase activity 5/946 145/18639 0.0344827586206897 0.679412407960924 0.865074092310513 0.99996521761986 GO:0005548 phospholipid transporter activity 2/946 68/18639 0.0294117647058824 0.579498818554906 0.866237466153804 0.99996521761986 GO:0140223 general transcription initiation factor activity 2/946 68/18639 0.0294117647058824 0.579498818554906 0.866237466153804 0.99996521761986 GO:0015108 chloride transmembrane transporter activity 4/946 121/18639 0.0330578512396694 0.651337515069977 0.868509485440036 0.99996521761986 GO:0015293 symporter activity 5/946 146/18639 0.0342465753424658 0.674758898317356 0.868917112796294 0.99996521761986 GO:0098960 postsynaptic neurotransmitter receptor activity 2/946 69/18639 0.0289855072463768 0.571100284952661 0.871580167513601 0.99996521761986 GO:0015085 calcium ion transmembrane transporter activity 5/946 147/18639 0.0340136054421769 0.670168701730164 0.872667330256839 0.99996521761986 GO:0004177 aminopeptidase activity 1/946 40/18639 0.025 0.49257399577167 0.875782831773771 0.99996521761986 GO:0050997 quaternary ammonium group binding 1/946 40/18639 0.025 0.49257399577167 0.875782831773771 0.99996521761986 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/946 268/18639 0.0373134328358209 0.735185068315926 0.878605321427178 0.99996521761986 GO:0004175 endopeptidase activity 16/946 405/18639 0.0395061728395062 0.778388536528071 0.879298373028362 0.99996521761986 GO:0140299 molecular sensor activity 2/946 71/18639 0.028169014084507 0.555012952982164 0.881680722126248 0.99996521761986 GO:0140828 metal cation:monoatomic cation antiporter activity 1/946 41/18639 0.024390243902439 0.4805599958748 0.882100883343318 0.99996521761986 GO:0004679 AMP-activated protein kinase activity 9/946 248/18639 0.0362903225806452 0.71502676805565 0.887704082833973 0.99996521761986 GO:0031492 nucleosomal DNA binding 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.99996521761986 GO:0035198 miRNA binding 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.99996521761986 GO:0051879 Hsp90 protein binding 1/946 42/18639 0.0238095238095238 0.469118091211114 0.888097902611907 0.99996521761986 GO:0140104 molecular carrier activity 9/946 249/18639 0.036144578313253 0.712155174609644 0.890331836037047 0.99996521761986 GO:0004521 RNA endonuclease activity 2/946 73/18639 0.0273972602739726 0.539807118653885 0.891042265967305 0.99996521761986 GO:0004519 endonuclease activity 4/946 127/18639 0.031496062992126 0.620565663964309 0.891439583026649 0.99996521761986 GO:0019783 ubiquitin-like protein peptidase activity 4/946 127/18639 0.031496062992126 0.620565663964309 0.891439583026649 0.99996521761986 GO:0019787 ubiquitin-like protein transferase activity 19/946 479/18639 0.0396659707724426 0.781537028781773 0.893260960802032 0.99996521761986 GO:0005319 lipid transporter activity 6/946 178/18639 0.0337078651685393 0.664144713400005 0.893695540878459 0.99996521761986 GO:0005245 voltage-gated calcium channel activity 1/946 43/18639 0.0232558139534884 0.458208368159693 0.89379018546017 0.99996521761986 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/946 43/18639 0.0232558139534884 0.458208368159693 0.89379018546017 0.99996521761986 GO:0008017 microtubule binding 10/946 276/18639 0.036231884057971 0.713875356190826 0.89877533849563 0.99996521761986 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/946 44/18639 0.0227272727272727 0.447794541610609 0.899193201407399 0.99996521761986 GO:0003725 double-stranded RNA binding 2/946 75/18639 0.0266666666666667 0.525412262156448 0.899711977640305 0.99996521761986 GO:0005253 monoatomic anion channel activity 3/946 103/18639 0.029126213592233 0.573872616433014 0.89995551050609 0.99996521761986 GO:0140303 intramembrane lipid transporter activity 1/946 45/18639 0.0222222222222222 0.43784355179704 0.904321635474008 0.99996521761986 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/946 46/18639 0.0217391304347826 0.428325213714496 0.909189427925422 0.99996521761986 GO:0004497 monooxygenase activity 3/946 106/18639 0.0283018867924528 0.557630938609438 0.910296005746852 0.99996521761986 GO:0061749 forked DNA-dependent helicase activity 1/946 47/18639 0.0212765957446809 0.419211911295038 0.913809812004514 0.99996521761986 GO:0140359 ABC-type transporter activity 1/946 47/18639 0.0212765957446809 0.419211911295038 0.913809812004514 0.99996521761986 GO:0140938 histone H3 methyltransferase activity 1/946 47/18639 0.0212765957446809 0.419211911295038 0.913809812004514 0.99996521761986 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/946 47/18639 0.0212765957446809 0.419211911295038 0.913809812004514 0.99996521761986 GO:0015370 solute:sodium symporter activity 2/946 79/18639 0.0253164556962025 0.498809109642198 0.915154116415153 0.99996521761986 GO:0008188 neuropeptide receptor activity 1/946 48/18639 0.0208333333333333 0.410478329809725 0.918195349754284 0.99996521761986 GO:0009378 four-way junction helicase activity 1/946 48/18639 0.0208333333333333 0.410478329809725 0.918195349754284 0.99996521761986 GO:0036121 double-stranded DNA helicase activity 1/946 48/18639 0.0208333333333333 0.410478329809725 0.918195349754284 0.99996521761986 GO:0043138 3'-5' DNA helicase activity 1/946 48/18639 0.0208333333333333 0.410478329809725 0.918195349754284 0.99996521761986 GO:0016779 nucleotidyltransferase activity 4/946 136/18639 0.0294117647058824 0.579498818554906 0.919263179038021 0.99996521761986 GO:0046943 carboxylic acid transmembrane transporter activity 6/946 188/18639 0.0319148936170213 0.628817866942558 0.920012942235501 0.99996521761986 GO:0016755 aminoacyltransferase activity 19/946 496/18639 0.0383064516129032 0.754750477392075 0.921644209539698 0.99996521761986 GO:0005342 organic acid transmembrane transporter activity 6/946 189/18639 0.0317460317460317 0.625490788281486 0.922302448763572 0.99996521761986 GO:0005004 GPI-linked ephrin receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0005008 hepatocyte growth factor receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0005009 insulin receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0005011 macrophage colony-stimulating factor receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0005020 stem cell factor receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0008288 boss receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0036332 placental growth factor receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0038062 protein tyrosine kinase collagen receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0060175 brain-derived neurotrophic factor receptor activity 1/946 49/18639 0.0204081632653061 0.402101221038098 0.922357966027344 0.99996521761986 GO:0140097 catalytic activity, acting on DNA 12/946 336/18639 0.0357142857142857 0.703677136816672 0.924460688164539 0.99996521761986 GO:0005006 epidermal growth factor receptor activity 1/946 50/18639 0.02 0.394059196617336 0.926308980773881 0.99996521761986 GO:0005007 fibroblast growth factor receptor activity 1/946 50/18639 0.02 0.394059196617336 0.926308980773881 0.99996521761986 GO:0005017 platelet-derived growth factor receptor activity 1/946 50/18639 0.02 0.394059196617336 0.926308980773881 0.99996521761986 GO:0005019 platelet-derived growth factor beta-receptor activity 1/946 50/18639 0.02 0.394059196617336 0.926308980773881 0.99996521761986 GO:0005010 insulin-like growth factor receptor activity 1/946 51/18639 0.0196078431372549 0.386332545703271 0.930059139695174 0.99996521761986 GO:0005030 neurotrophin receptor activity 1/946 51/18639 0.0196078431372549 0.386332545703271 0.930059139695174 0.99996521761986 GO:0005048 signal sequence binding 1/946 51/18639 0.0196078431372549 0.386332545703271 0.930059139695174 0.99996521761986 GO:0005272 sodium channel activity 1/946 51/18639 0.0196078431372549 0.386332545703271 0.930059139695174 0.99996521761986 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 8/946 243/18639 0.0329218106995885 0.648657113773393 0.930511284551614 0.99996521761986 GO:0008236 serine-type peptidase activity 6/946 194/18639 0.0309278350515464 0.609369891676293 0.932908448135905 0.99996521761986 GO:0004676 3-phosphoinositide-dependent protein kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0004711 ribosomal protein S6 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0035175 histone H3S10 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0035979 histone H2AXS139 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0044022 histone H3S28 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0044023 histone H4S1 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0044024 histone H2AS1 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0044025 histone H2BS14 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0072354 histone H3T3 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0072371 histone H2AS121 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0072518 Rho-dependent protein serine/threonine kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0140823 histone H2BS36 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0140855 histone H3S57 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0140995 histone H2A kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0140997 histone H4 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0140998 histone H2B kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:1990244 histone H2AT120 kinase activity 8/946 245/18639 0.0326530612244898 0.643361953660957 0.934119688378027 0.99996521761986 GO:0004677 DNA-dependent protein kinase activity 8/946 246/18639 0.032520325203252 0.6407466611664 0.93586177270256 0.99996521761986 GO:0140857 histone H3T45 kinase activity 8/946 246/18639 0.032520325203252 0.6407466611664 0.93586177270256 0.99996521761986 GO:0005003 ephrin receptor activity 1/946 53/18639 0.0188679245283019 0.371753959072959 0.93699717475947 0.99996521761986 GO:0005005 transmembrane-ephrin receptor activity 1/946 53/18639 0.0188679245283019 0.371753959072959 0.93699717475947 0.99996521761986 GO:0038064 collagen receptor activity 1/946 53/18639 0.0188679245283019 0.371753959072959 0.93699717475947 0.99996521761986 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/946 53/18639 0.0188679245283019 0.371753959072959 0.93699717475947 0.99996521761986 GO:0035402 histone H3T11 kinase activity 8/946 247/18639 0.0323886639676113 0.638152545129289 0.937563436115908 0.99996521761986 GO:0035403 histone H3T6 kinase activity 8/946 247/18639 0.0323886639676113 0.638152545129289 0.937563436115908 0.99996521761986 GO:0016758 hexosyltransferase activity 6/946 197/18639 0.0304568527918782 0.600090147132999 0.938638682348285 0.99996521761986 GO:0046982 protein heterodimerization activity 13/946 369/18639 0.035230352303523 0.6941422162636 0.938780935558589 0.99996521761986 GO:0140463 chromatin-protein adaptor activity 1/946 54/18639 0.0185185185185185 0.364869626497533 0.940203925683689 0.99996521761986 GO:0017171 serine hydrolase activity 6/946 198/18639 0.0303030303030303 0.597059388814146 0.940449681958343 0.99996521761986 GO:0061659 ubiquitin-like protein ligase activity 13/946 372/18639 0.0349462365591398 0.6885442951647 0.942802521189946 0.99996521761986 GO:0003727 single-stranded RNA binding 2/946 89/18639 0.0224719101123595 0.44276314226667 0.944546068891391 0.99996521761986 GO:0008509 monoatomic anion transmembrane transporter activity 4/946 149/18639 0.0268456375838926 0.528938518949444 0.948222332649478 0.99996521761986 GO:0043021 ribonucleoprotein complex binding 5/946 177/18639 0.0282485875706215 0.556580786182678 0.94954997264117 0.99996521761986 GO:0017116 single-stranded DNA helicase activity 1/946 58/18639 0.0172413793103448 0.339706203980462 0.951481123962838 0.99996521761986 GO:0061980 regulatory RNA binding 1/946 58/18639 0.0172413793103448 0.339706203980462 0.951481123962838 0.99996521761986 GO:0070888 E-box binding 1/946 59/18639 0.0169491525423729 0.333948471709607 0.953951327758713 0.99996521761986 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/946 60/18639 0.0166666666666667 0.32838266384778 0.956295894170998 0.99996521761986 GO:0008276 protein methyltransferase activity 2/946 95/18639 0.0210526315789474 0.414799154334038 0.957223438413002 0.99996521761986 GO:0004674 protein serine/threonine kinase activity 15/946 433/18639 0.0346420323325635 0.682550571508088 0.957665579908867 0.99996521761986 GO:0004386 helicase activity 4/946 155/18639 0.0258064516129032 0.50846347950624 0.958070696700512 0.99996521761986 GO:0015179 L-amino acid transmembrane transporter activity 1/946 62/18639 0.0161290322580645 0.3177896746914 0.960633325386901 0.99996521761986 GO:0030594 neurotransmitter receptor activity 2/946 97/18639 0.0206185567010309 0.406246594450862 0.960794672780581 0.99996521761986 GO:0031490 chromatin DNA binding 3/946 128/18639 0.0234375 0.461788121035941 0.960933095488041 0.99996521761986 GO:0140658 ATP-dependent chromatin remodeler activity 4/946 158/18639 0.0253164556962025 0.498809109642198 0.962317485063101 0.99996521761986 GO:0008170 N-methyltransferase activity 2/946 98/18639 0.0204081632653061 0.402101221038098 0.962471269666188 0.99996521761986 GO:0022824 transmitter-gated monoatomic ion channel activity 1/946 63/18639 0.0158730158730159 0.312745394140743 0.962638001824646 0.99996521761986 GO:0022835 transmitter-gated channel activity 1/946 63/18639 0.0158730158730159 0.312745394140743 0.962638001824646 0.99996521761986 GO:0140597 protein carrier chaperone 5/946 188/18639 0.0265957446808511 0.524014889118798 0.96490527480663 0.99996521761986 GO:0042054 histone methyltransferase activity 1/946 67/18639 0.0149253731343284 0.29407402732637 0.969687412712112 0.99996521761986 GO:0004842 ubiquitin-protein transferase activity 15/946 449/18639 0.0334075723830735 0.658228056710472 0.970666075512278 0.99996521761986 GO:0015103 inorganic anion transmembrane transporter activity 4/946 165/18639 0.0242424242424242 0.477647511051317 0.970722321837643 0.99996521761986 GO:0030145 manganese ion binding 1/946 68/18639 0.0147058823529412 0.289749409277453 0.971231441765221 0.99996521761986 GO:0061630 ubiquitin protein ligase activity 11/946 353/18639 0.0311614730878187 0.613973252519929 0.972539442724456 0.99996521761986 GO:0016279 protein-lysine N-methyltransferase activity 1/946 69/18639 0.0144927536231884 0.285550142476331 0.972696901680686 0.99996521761986 GO:0016278 lysine N-methyltransferase activity 1/946 70/18639 0.0142857142857143 0.281470854726669 0.974087786495445 0.99996521761986 GO:0140101 catalytic activity, acting on a tRNA 3/946 139/18639 0.0215827338129496 0.425243737356838 0.974666994026199 0.99996521761986 GO:0004713 protein tyrosine kinase activity 3/946 140/18639 0.0214285714285714 0.422206282090003 0.975657401336943 0.99996521761986 GO:0004843 cysteine-type deubiquitinase activity 2/946 108/18639 0.0185185185185185 0.364869626497533 0.975855734166144 0.99996521761986 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/946 73/18639 0.0136986301369863 0.269903559326943 0.977849949452692 0.99996521761986 GO:0005244 voltage-gated monoatomic ion channel activity 4/946 173/18639 0.023121387283237 0.455559764875533 0.97817110020224 0.99996521761986 GO:0003678 DNA helicase activity 1/946 74/18639 0.0135135135135135 0.266256213930633 0.978978568854704 0.99996521761986 GO:0022832 voltage-gated channel activity 4/946 175/18639 0.0228571428571429 0.45035336756267 0.979732433698481 0.99996521761986 GO:0043022 ribosome binding 2/946 112/18639 0.0178571428571429 0.351838568408336 0.979798864881437 0.99996521761986 GO:0015291 secondary active transmembrane transporter activity 8/946 287/18639 0.0278745644599303 0.549211423856915 0.980110474140906 0.99996521761986 GO:0004252 serine-type endopeptidase activity 4/946 176/18639 0.0227272727272727 0.447794541610609 0.980473015308027 0.99996521761986 GO:0016887 ATP hydrolysis activity 13/946 417/18639 0.0311750599520384 0.614240953959877 0.980808342808601 0.99996521761986 GO:0003724 RNA helicase activity 1/946 77/18639 0.012987012987013 0.255882595206062 0.982031268585558 0.99996521761986 GO:0005216 monoatomic ion channel activity 14/946 448/18639 0.03125 0.615717494714588 0.98351900904354 0.99996521761986 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/946 181/18639 0.0220994475138122 0.43542452664899 0.983807920714376 0.99996521761986 GO:0008186 ATP-dependent activity, acting on RNA 1/946 79/18639 0.0126582278481013 0.249404554821099 0.983816173002988 0.99996521761986 GO:0000510 H3-H4 histone complex chaperone activity 3/946 151/18639 0.0198675496688742 0.391449533063579 0.984380786039012 0.99996521761986 GO:0140584 chromatin extrusion motor activity 3/946 151/18639 0.0198675496688742 0.391449533063579 0.984380786039012 0.99996521761986 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/946 151/18639 0.0198675496688742 0.391449533063579 0.984380786039012 0.99996521761986 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/946 151/18639 0.0198675496688742 0.391449533063579 0.984380786039012 0.99996521761986 GO:0015616 DNA translocase activity 3/946 152/18639 0.0197368421052632 0.388874207188161 0.985004855213979 0.99996521761986 GO:0140674 ATP-dependent histone chaperone activity 3/946 152/18639 0.0197368421052632 0.388874207188161 0.985004855213979 0.99996521761986 GO:0061775 cohesin loader activity 3/946 153/18639 0.0196078431372549 0.386332545703271 0.985604987840528 0.99996521761986 GO:0016741 transferase activity, transferring one-carbon groups 5/946 215/18639 0.0232558139534884 0.458208368159693 0.986217838712669 0.99996521761986 GO:0003689 DNA clamp loader activity 3/946 160/18639 0.01875 0.369430496828753 0.989204944719544 0.99996521761986 GO:0106310 protein serine kinase activity 10/946 361/18639 0.0277008310249307 0.545788360965839 0.989302951286346 0.99996521761986 GO:0015081 sodium ion transmembrane transporter activity 3/946 164/18639 0.0182926829268293 0.3604199969061 0.990854905295729 0.99996521761986 GO:0140713 histone chaperone activity 3/946 164/18639 0.0182926829268293 0.3604199969061 0.990854905295729 0.99996521761986 GO:0005261 monoatomic cation channel activity 9/946 341/18639 0.0263929618768328 0.520019467676837 0.991292254447998 0.99996521761986 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/946 167/18639 0.0179640718562874 0.353945386183236 0.991929865312076 0.99996521761986 GO:0022836 gated channel activity 8/946 318/18639 0.0251572327044025 0.495671945430612 0.992436177503446 0.99996521761986 GO:0003730 mRNA 3'-UTR binding 6/946 262/18639 0.0229007633587786 0.451212820554202 0.992656926071071 0.99996521761986 GO:0015297 antiporter activity 2/946 135/18639 0.0148148148148148 0.291895701198027 0.992879734329115 0.99996521761986 GO:0099094 ligand-gated monoatomic cation channel activity 2/946 136/18639 0.0147058823529412 0.289749409277453 0.993199413503556 0.99996521761986 GO:0008168 methyltransferase activity 4/946 204/18639 0.0196078431372549 0.386332545703271 0.99331189222994 0.99996521761986 GO:0005249 voltage-gated potassium channel activity 1/946 98/18639 0.0102040816326531 0.201050610519049 0.994013312853988 0.99996521761986 GO:0141003 histone H2AX kinase activity 9/946 354/18639 0.0254237288135593 0.50092270756441 0.994193269479306 0.99996521761986 GO:0140996 histone H3 kinase activity 9/946 357/18639 0.0252100840336134 0.496713273047062 0.994718937124341 0.99996521761986 GO:0008094 ATP-dependent activity, acting on DNA 4/946 210/18639 0.019047619047619 0.375294472968892 0.994719079103114 0.99996521761986 GO:0022843 voltage-gated monoatomic cation channel activity 2/946 143/18639 0.013986013986014 0.275565871760375 0.995075445845577 0.99996521761986 GO:0140098 catalytic activity, acting on RNA 10/946 387/18639 0.0258397932816537 0.509120409066326 0.995113675600821 0.99996521761986 GO:0015171 amino acid transmembrane transporter activity 1/946 102/18639 0.00980392156862745 0.193166272851635 0.995144840797867 0.99996521761986 GO:0035173 histone kinase activity 9/946 360/18639 0.025 0.49257399577167 0.995199437216985 0.99996521761986 GO:0015276 ligand-gated monoatomic ion channel activity 3/946 186/18639 0.0161290322580645 0.3177896746914 0.996387472500669 0.99996521761986 GO:0022834 ligand-gated channel activity 3/946 188/18639 0.0159574468085106 0.314408933471279 0.996684188822749 0.99996521761986 GO:0035401 histone H3Y41 kinase activity 1/946 115/18639 0.00869565217391304 0.171330085485798 0.997543203537219 0.99996521761986 GO:0140801 histone H2AXY142 kinase activity 1/946 115/18639 0.00869565217391304 0.171330085485798 0.997543203537219 0.99996521761986 GO:0008528 G protein-coupled peptide receptor activity 1/946 122/18639 0.00819672131147541 0.16149967074481 0.998297898361174 0.99996521761986 GO:0046873 metal ion transmembrane transporter activity 11/946 450/18639 0.0244444444444444 0.481627906976744 0.99838534486739 0.99996521761986 GO:0005267 potassium channel activity 1/946 124/18639 0.00806451612903226 0.1588948373457 0.998467374908293 0.99996521761986 GO:0001653 peptide receptor activity 1/946 128/18639 0.0078125 0.153929373678647 0.998757427727655 0.99996521761986 GO:0015079 potassium ion transmembrane transporter activity 1/946 160/18639 0.00625 0.123143498942918 0.999768431786494 0.99996521761986 GO:0045182 translation regulator activity 5/946 356/18639 0.0140449438202247 0.276726963916669 0.999946916960854 0.99996521761986 GO:0030371 translation repressor activity 4/946 329/18639 0.0121580547112462 0.239549663597165 0.99996521761986 0.99996521761986