ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	143/2251	495/18639	0.288888888888889	2.39209240337628	1.84219467788933e-24	2.18668508265464e-21
GO:0140297	DNA-binding transcription factor binding	136/2251	488/18639	0.278688524590164	2.30763012431633	9.86970073737431e-22	5.85766738763165e-19
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	101/2251	349/18639	0.289398280802292	2.39631033135225	1.14947421084037e-17	4.54808629422508e-15
GO:0042393	histone binding	78/2251	247/18639	0.315789473684211	2.61483784984451	2.98679721293211e-16	8.86332072937604e-14
GO:0016922	nuclear receptor binding	50/2251	137/18639	0.364963503649635	3.02201454665728	1.31989675615504e-13	3.13343489911206e-11
GO:0140030	modification-dependent protein binding	56/2251	173/18639	0.323699421965318	2.68033475167106	1.49015925478358e-12	2.94803172571352e-10
GO:0003714	transcription corepressor activity	62/2251	204/18639	0.303921568627451	2.51656779993206	2.20352222835389e-12	3.73654412150867e-10
GO:0003713	transcription coactivator activity	72/2251	256/18639	0.28125	2.32883996001777	2.56683269974053e-12	3.80853801824002e-10
GO:0044389	ubiquitin-like protein ligase binding	83/2251	322/18639	0.257763975155279	2.13436816211428	8.97127316668726e-12	1.18321124987309e-09
GO:0031625	ubiquitin protein ligase binding	77/2251	302/18639	0.254966887417219	2.1112073809727	8.89431428397459e-11	9.6822762946838e-09
GO:0023023	MHC protein complex binding	21/2251	37/18639	0.567567567567568	4.69964100039622	8.97262335648878e-11	9.6822762946838e-09
GO:0015631	tubulin binding	90/2251	385/18639	0.233766233766234	1.93565918754724	3.38909774753059e-10	3.35238252193235e-08
GO:0061775	cohesin loader activity	47/2251	153/18639	0.30718954248366	2.54362766874853	6.65313659880002e-10	6.07482549444279e-08
GO:0030695	GTPase regulator activity	106/2251	489/18639	0.216768916155419	1.79491596100438	9.62592480698923e-10	8.05468507005491e-08
GO:0004386	helicase activity	47/2251	155/18639	0.303225806451613	2.51080666657113	1.07453563796417e-09	8.05468507005491e-08
GO:0060589	nucleoside-triphosphatase regulator activity	106/2251	490/18639	0.216326530612245	1.79125286720641	1.08571997574455e-09	8.05468507005491e-08
GO:0140658	ATP-dependent chromatin remodeler activity	47/2251	158/18639	0.29746835443038	2.46313312226915	2.16027289372064e-09	1.50837877932141e-07
GO:0019787	ubiquitin-like protein transferase activity	103/2251	479/18639	0.215031315240084	1.78052806964012	2.6347369484357e-09	1.65538523614252e-07
GO:0140713	histone chaperone activity	48/2251	164/18639	0.292682926829268	2.4235082510754	2.64973205448255e-09	1.65538523614252e-07
GO:0140463	chromatin-protein adaptor activity	24/2251	54/18639	0.444444444444444	3.68014215904043	3.03154294518552e-09	1.79922073796761e-07
GO:0003725	double-stranded RNA binding	29/2251	75/18639	0.386666666666667	3.20172367836517	3.72829968535684e-09	2.10157821231825e-07
GO:0000510	H3-H4 histone complex chaperone activity	45/2251	151/18639	0.298013245033113	2.46764499074731	4.42623886334931e-09	2.10157821231825e-07
GO:0140584	chromatin extrusion motor activity	45/2251	151/18639	0.298013245033113	2.46764499074731	4.42623886334931e-09	2.10157821231825e-07
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	45/2251	151/18639	0.298013245033113	2.46764499074731	4.42623886334931e-09	2.10157821231825e-07
GO:0140849	ATP-dependent H2AZ histone chaperone activity	45/2251	151/18639	0.298013245033113	2.46764499074731	4.42623886334931e-09	2.10157821231825e-07
GO:0140597	protein carrier chaperone	52/2251	188/18639	0.276595744680851	2.29030123727516	5.14796387376441e-09	2.35024350698398e-07
GO:0015616	DNA translocase activity	45/2251	152/18639	0.296052631578947	2.45141048422923	5.56064288536242e-09	2.35731539461614e-07
GO:0140674	ATP-dependent histone chaperone activity	45/2251	152/18639	0.296052631578947	2.45141048422923	5.56064288536242e-09	2.35731539461614e-07
GO:0023026	MHC class II protein complex binding	16/2251	27/18639	0.592592592592593	4.9068562120539	6.83441110771141e-09	2.79739516719084e-07
GO:0019902	phosphatase binding	52/2251	190/18639	0.273684210526316	2.26619280319858	7.64429902365281e-09	3.02459431369196e-07
GO:0003689	DNA clamp loader activity	46/2251	160/18639	0.2875	2.38059195912928	1.04775507105999e-08	4.01188796563939e-07
GO:0004842	ubiquitin-protein transferase activity	96/2251	449/18639	0.21380846325167	1.77040246403727	1.23561479162325e-08	4.58335861767748e-07
GO:0004197	cysteine-type endopeptidase activity	31/2251	88/18639	0.352272727272727	2.91693085901216	1.49704548317997e-08	5.38482723798372e-07
GO:0016755	aminoacyltransferase activity	103/2251	496/18639	0.207661290322581	1.71950190596294	1.81967571139392e-08	6.35280902771938e-07
GO:0070063	RNA polymerase binding	24/2251	59/18639	0.406779661016949	3.36826570488446	2.5504010480077e-08	8.64950298281467e-07
GO:0019207	kinase regulator activity	68/2251	287/18639	0.236933797909408	1.96188763182295	2.74703813354803e-08	9.05759517922641e-07
GO:0061659	ubiquitin-like protein ligase activity	82/2251	372/18639	0.220430107526882	1.82523179662086	3.513478977802e-08	1.1271620396354e-06
GO:0001222	transcription corepressor binding	21/2251	49/18639	0.428571428571429	3.54870851050327	6.3916571480562e-08	1.99655185124808e-06
GO:0106310	protein serine kinase activity	79/2251	361/18639	0.218836565096953	1.812036755594	8.61175035694253e-08	2.62106350607456e-06
GO:0140566	histone reader activity	17/2251	35/18639	0.485714285714286	4.02186964523704	1.23033547237808e-07	3.65102051428196e-06
GO:0031072	heat shock protein binding	38/2251	131/18639	0.290076335877863	2.40192484425921	1.50492208427288e-07	4.35693296105345e-06
GO:0140104	molecular carrier activity	59/2251	249/18639	0.236947791164659	1.96200350045228	2.23132375735732e-07	6.3061459523408e-06
GO:0046332	SMAD binding	27/2251	79/18639	0.341772151898734	2.82998273622412	2.55221965415422e-07	7.04531332437454e-06
GO:0008094	ATP-dependent activity, acting on DNA	52/2251	210/18639	0.247619047619048	2.05036491717967	2.66439015935072e-07	7.14132552138317e-06
GO:0004674	protein serine/threonine kinase activity	89/2251	433/18639	0.20554272517321	1.70195950888648	2.70732644028848e-07	7.14132552138317e-06
GO:0061630	ubiquitin protein ligase activity	76/2251	353/18639	0.215297450424929	1.78273175409607	3.00658122014592e-07	7.75828675720262e-06
GO:0050681	nuclear androgen receptor binding	14/2251	26/18639	0.538461538461538	4.45863376960667	3.15549475559883e-07	7.96930271254427e-06
GO:0042605	peptide antigen binding	19/2251	45/18639	0.422222222222222	3.49613505108841	3.59284514029838e-07	8.75832496819004e-06
GO:0008017	microtubule binding	63/2251	276/18639	0.228260869565217	1.89007301102891	3.65736927728926e-07	8.75832496819004e-06
GO:0016887	ATP hydrolysis activity	86/2251	417/18639	0.206235011990408	1.70769186516624	3.68926915256531e-07	8.75832496819004e-06
GO:0001221	transcription coregulator binding	34/2251	115/18639	0.295652173913043	2.44809456666602	4.07797728758044e-07	9.47423171870881e-06
GO:0005096	GTPase activator activity	62/2251	271/18639	0.228782287822878	1.89439052098206	4.15046376893731e-07	9.47423171870881e-06
GO:0019887	protein kinase regulator activity	59/2251	255/18639	0.231372549019608	1.91583871220634	5.26420909190181e-07	1.17898418718631e-05
GO:0045296	cadherin binding	72/2251	334/18639	0.215568862275449	1.78497913103158	5.81542857747969e-07	1.27831735582748e-05
GO:0005164	tumor necrosis factor receptor binding	15/2251	31/18639	0.483870967741935	4.00660638282627	7.29063408938427e-07	1.57345139347257e-05
GO:0008186	ATP-dependent activity, acting on RNA	26/2251	79/18639	0.329113924050633	2.72516856080842	9.72582282086818e-07	2.02783784448997e-05
GO:0140996	histone H3 kinase activity	75/2251	357/18639	0.210084033613445	1.73956299534474	9.73772174691899e-07	2.02783784448997e-05
GO:0046966	nuclear thyroid hormone receptor binding	14/2251	28/18639	0.5	4.14015992892048	1.03517965453946e-06	2.10919258062819e-05
GO:0001217	DNA-binding transcription repressor activity	62/2251	278/18639	0.223021582733813	1.84669004023791	1.04837710410331e-06	2.10919258062819e-05
GO:0035173	histone kinase activity	75/2251	360/18639	0.208333333333333	1.7250666370502	1.35879005370861e-06	2.68813965625354e-05
GO:0042974	nuclear retinoic acid receptor binding	13/2251	25/18639	0.52	4.3057663260773	1.42521251221442e-06	2.77332336393199e-05
GO:0140035	ubiquitin-like protein reader activity	12/2251	22/18639	0.545454545454545	4.51653810427689	1.87882562854784e-06	3.597041969494e-05
GO:0019903	protein phosphatase binding	38/2251	144/18639	0.263888888888889	2.18508440693025	2.03004577564484e-06	3.82486402490544e-05
GO:0003724	RNA helicase activity	25/2251	77/18639	0.324675324675325	2.68841553826005	2.07413466709006e-06	3.84185506812226e-05
GO:0031490	chromatin DNA binding	35/2251	128/18639	0.2734375	2.26414996112839	2.10379595137276e-06	3.84185506812226e-05
GO:0141003	histone H2AX kinase activity	73/2251	354/18639	0.206214689265537	1.70752358650393	2.76607101834241e-06	4.97473681632187e-05
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	59/2251	268/18639	0.220149253731343	1.82290623736051	2.93486870896184e-06	5.19953605602643e-05
GO:0140097	catalytic activity, acting on DNA	70/2251	336/18639	0.208333333333333	1.7250666370502	3.02120943464902e-06	5.27378764548292e-05
GO:0008234	cysteine-type peptidase activity	45/2251	187/18639	0.240641711229947	1.99259034012216	3.77497139681135e-06	6.4940449971233e-05
GO:0140857	histone H3T45 kinase activity	55/2251	246/18639	0.223577235772358	1.85129102512704	3.84866475035321e-06	6.52623579809894e-05
GO:0035402	histone H3T11 kinase activity	55/2251	247/18639	0.222672064777328	1.84379591976216	4.37877470618178e-06	7.21889663366357e-05
GO:0035403	histone H3T6 kinase activity	55/2251	247/18639	0.222672064777328	1.84379591976216	4.37877470618178e-06	7.21889663366357e-05
GO:0004679	AMP-activated protein kinase activity	55/2251	248/18639	0.221774193548387	1.83636125879537	4.97620111274515e-06	8.09143934360068e-05
GO:0042608	T cell receptor binding	8/2251	11/18639	0.727272727272727	6.02205080570252	5.2615442957744e-06	8.4398014582219e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	54/2251	243/18639	0.222222222222222	1.84007107952021	5.67473318911676e-06	8.89316153798879e-05
GO:0140034	methylation-dependent protein binding	24/2251	76/18639	0.315789473684211	2.61483784984451	5.69402086678305e-06	8.89316153798879e-05
GO:0140033	acetylation-dependent protein binding	12/2251	24/18639	0.5	4.14015992892048	6.22232695501457e-06	9.2339495625158e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0004711	ribosomal protein S6 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0035175	histone H3S10 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0035979	histone H2AXS139 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0044022	histone H3S28 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0044023	histone H4S1 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0044024	histone H2AS1 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0044025	histone H2BS14 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0072354	histone H3T3 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0072371	histone H2AS121 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0140823	histone H2BS36 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0140855	histone H3S57 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0140995	histone H2A kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0140997	histone H4 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0140998	histone H2B kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:1990244	histone H2AT120 kinase activity	54/2251	245/18639	0.220408163265306	1.82505009111597	7.31247901328126e-06	9.2339495625158e-05
GO:0004677	DNA-dependent protein kinase activity	54/2251	246/18639	0.219512195121951	1.81763118830655	8.28667677472975e-06	0.000103539845595834
GO:0031267	small GTPase binding	60/2251	283/18639	0.212014134275618	1.75554484618536	8.50803217378242e-06	0.000105198272815414
GO:1990841	promoter-specific chromatin binding	22/2251	68/18639	0.323529411764706	2.6789270128309	8.92532303945147e-06	0.000109220190183803
GO:0051020	GTPase binding	65/2251	315/18639	0.206349206349206	1.70863743098305	9.31184239329505e-06	0.000112787315518788
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	12/2251	25/18639	0.48	3.97455353176366	1.06504325945223e-05	0.000127697611007051
GO:0032813	tumor necrosis factor receptor superfamily binding	18/2251	50/18639	0.36	2.98091514882275	1.09509069439709e-05	0.000129987265424934
GO:0140311	protein sequestering activity	14/2251	33/18639	0.424242424242424	3.51286296999313	1.17281646859928e-05	0.000137834965171024
GO:0035064	methylated histone binding	23/2251	74/18639	0.310810810810811	2.57361292878841	1.18990741451899e-05	0.000138472558924906
GO:0140313	molecular sequestering activity	19/2251	55/18639	0.345454545454545	2.8604741327087	1.25029941825616e-05	0.000144087903832045
GO:0061733	protein-lysine-acetyltransferase activity	17/2251	47/18639	0.361702127659574	2.9950093102829	1.7817082368069e-05	0.000203354584335557
GO:0140036	ubiquitin-modified protein reader activity	10/2251	19/18639	0.526315789473684	4.35806308307419	2.1218817140751e-05	0.000239873675676871
GO:0140693	molecular condensate scaffold activity	17/2251	48/18639	0.354166666666667	2.93261328298534	2.4502064360944e-05	0.000274376890532458
GO:0070577	lysine-acetylated histone binding	11/2251	23/18639	0.478260869565217	3.96015297548916	2.61549799355335e-05	0.000290149169939049
GO:0019209	kinase activator activity	36/2251	148/18639	0.243243243243243	2.01413185731267	2.64321943885703e-05	0.000290509395733638
GO:0051219	phosphoprotein binding	26/2251	93/18639	0.279569892473118	2.31492813229962	2.71490624154241e-05	0.000295650798964297
GO:0017124	SH3 domain binding	30/2251	115/18639	0.260869565217391	2.1600834411759	2.9590058128816e-05	0.000319303627262769
GO:0140375	immune receptor activity	37/2251	156/18639	0.237179487179487	1.96392201756484	3.71230424043435e-05	0.000396982444450052
GO:0004715	non-membrane spanning protein tyrosine kinase activity	16/2251	45/18639	0.355555555555556	2.94411372723234	3.99948041884129e-05	0.000423873505103983
GO:0001098	basal transcription machinery binding	19/2251	60/18639	0.316666666666667	2.6221012883163	5.02134570013648e-05	0.000522836609303685
GO:0001099	basal RNA polymerase II transcription machinery binding	19/2251	60/18639	0.316666666666667	2.6221012883163	5.02134570013648e-05	0.000522836609303685
GO:0071889	14-3-3 protein binding	13/2251	33/18639	0.393939393939394	3.2619441864222	6.16086889963076e-05	0.000635908815987975
GO:0004402	histone acetyltransferase activity	15/2251	42/18639	0.357142857142857	2.95725709208606	6.53527006385761e-05	0.000663022697931537
GO:0043175	RNA polymerase core enzyme binding	15/2251	42/18639	0.357142857142857	2.95725709208606	6.53527006385761e-05	0.000663022697931537
GO:0032182	ubiquitin-like protein binding	30/2251	120/18639	0.25	2.07007996446024	7.00566136176826e-05	0.000704722036984655
GO:0035925	mRNA 3'-UTR AU-rich region binding	12/2251	30/18639	0.4	3.31212794313638	9.91087312450325e-05	0.000959949065132972
GO:0043995	histone H4K5 acetyltransferase activity	12/2251	30/18639	0.4	3.31212794313638	9.91087312450325e-05	0.000959949065132972
GO:0043996	histone H4K8 acetyltransferase activity	12/2251	30/18639	0.4	3.31212794313638	9.91087312450325e-05	0.000959949065132972
GO:0043997	histone H4K12 acetyltransferase activity	12/2251	30/18639	0.4	3.31212794313638	9.91087312450325e-05	0.000959949065132972
GO:0042277	peptide binding	51/2251	249/18639	0.204819277108434	1.69596912750959	9.94723968082187e-05	0.000959949065132972
GO:0034212	protein N-acetyltransferase activity	17/2251	53/18639	0.320754716981132	2.65595165251502	0.000103177864523273	0.000987678428944559
GO:0035591	signaling adaptor activity	31/2251	129/18639	0.24031007751938	1.98984430692302	0.000118334934203492	0.00112370853519636
GO:0010485	histone H4 acetyltransferase activity	13/2251	35/18639	0.371428571428571	3.0755473757695	0.000125704126593588	0.00118421268465547
GO:0001671	ATPase activator activity	11/2251	27/18639	0.407407407407407	3.37346364578706	0.000159046240336236	0.00148651879747332
GO:0005126	cytokine receptor binding	54/2251	275/18639	0.196363636363636	1.62595371753968	0.000198449231476758	0.00184030654502275
GO:0042826	histone deacetylase binding	30/2251	127/18639	0.236220472440945	1.95598106878133	0.000209148839712297	0.00192449358712013
GO:0036408	histone H3K14 acetyltransferase activity	11/2251	28/18639	0.392857142857143	3.25298280129466	0.000233514040339723	0.00211588676246756
GO:0051019	mitogen-activated protein kinase binding	11/2251	28/18639	0.392857142857143	3.25298280129466	0.000233514040339723	0.00211588676246756
GO:0048487	beta-tubulin binding	14/2251	42/18639	0.333333333333333	2.76010661928032	0.000263881970784701	0.00237293863122303
GO:0019208	phosphatase regulator activity	28/2251	117/18639	0.239316239316239	1.98161500871408	0.000265965173490476	0.00237368917994883
GO:0001784	phosphotyrosine residue binding	15/2251	47/18639	0.319148936170213	2.64265527377903	0.000276826437197421	0.00243402208113584
GO:0140938	histone H3 methyltransferase activity	15/2251	47/18639	0.319148936170213	2.64265527377903	0.000276826437197421	0.00243402208113584
GO:0140852	histone ubiquitin ligase activity	7/2251	13/18639	0.538461538461538	4.45863376960667	0.000328005211654269	0.00286281019289425
GO:0010484	histone H3 acetyltransferase activity	11/2251	29/18639	0.379310344827586	3.14081098056036	0.000335410606611754	0.00290607583976753
GO:0008080	N-acetyltransferase activity	19/2251	69/18639	0.27536231884058	2.28008807679679	0.000390083342504525	0.00335528208371646
GO:0005031	tumor necrosis factor receptor activity	6/2251	10/18639	0.6	4.96819191470458	0.000419514421630697	0.00350678604560308
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/2251	10/18639	0.6	4.96819191470458	0.000419514421630697	0.00350678604560308
GO:0032395	MHC class II receptor activity	6/2251	10/18639	0.6	4.96819191470458	0.000419514421630697	0.00350678604560308
GO:0045322	unmethylated CpG binding	6/2251	10/18639	0.6	4.96819191470458	0.000419514421630697	0.00350678604560308
GO:0031593	polyubiquitin modification-dependent protein binding	17/2251	59/18639	0.288135593220339	2.38585487429316	0.000436565056486259	0.00359863001423048
GO:0045309	protein phosphorylated amino acid binding	17/2251	59/18639	0.288135593220339	2.38585487429316	0.000436565056486259	0.00359863001423048
GO:0032452	histone demethylase activity	11/2251	30/18639	0.366666666666667	3.03611728120835	0.000472216955508277	0.00386566569785051
GO:0019783	ubiquitin-like protein peptidase activity	29/2251	127/18639	0.228346456692913	1.89078169982195	0.00048379969642188	0.0039278998237391
GO:0030295	protein kinase activator activity	31/2251	139/18639	0.223021582733813	1.84669004023791	0.000486437467640815	0.0039278998237391
GO:0043021	ribonucleoprotein complex binding	37/2251	177/18639	0.209039548022599	1.73091432056562	0.000562277035505194	0.00450961379151801
GO:0140457	protein demethylase activity	11/2251	31/18639	0.354838709677419	2.9381780140726	0.000652725026206906	0.00519989668528589
GO:0043130	ubiquitin binding	24/2251	100/18639	0.24	1.98727676588183	0.000676477100599465	0.00535318878941043
GO:0000993	RNA polymerase II complex binding	12/2251	36/18639	0.333333333333333	2.76010661928032	0.000717172617223018	0.00557297488174893
GO:0140789	histone phosphatase activity	30/2251	136/18639	0.220588235294118	1.82654114511198	0.000720360910158161	0.00557297488174893
GO:0003727	single-stranded RNA binding	22/2251	89/18639	0.247191011235955	2.04682063901687	0.000727726290371596	0.00557297488174893
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	22/2251	89/18639	0.247191011235955	2.04682063901687	0.000727726290371596	0.00557297488174893
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	22/2251	89/18639	0.247191011235955	2.04682063901687	0.000727726290371596	0.00557297488174893
GO:0001727	lipid kinase activity	13/2251	41/18639	0.317073170731707	2.62546727199835	0.000747638130985864	0.00568875936846296
GO:0019888	protein phosphatase regulator activity	25/2251	107/18639	0.233644859813084	1.93465417239275	0.000806395544750528	0.0060967612205024
GO:0004143	ATP-dependent diacylglycerol kinase activity	6/2251	11/18639	0.545454545454545	4.51653810427689	0.000828544222933188	0.00622456957355503
GO:0140793	histone H2AXY142 phosphatase activity	22/2251	90/18639	0.244444444444444	2.02407818747223	0.000855131710701013	0.00638390780252895
GO:0004896	cytokine receptor activity	23/2251	96/18639	0.239583333333333	1.98382663260773	0.000888823445486748	0.00653354724401156
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	9/2251	23/18639	0.391304347826087	3.24012516176385	0.000897193092480105	0.00653354724401156
GO:0044013	histone H2B acetyltransferase activity	9/2251	23/18639	0.391304347826087	3.24012516176385	0.000897193092480105	0.00653354724401156
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	9/2251	23/18639	0.391304347826087	3.24012516176385	0.000897193092480105	0.00653354724401156
GO:0019955	cytokine binding	31/2251	144/18639	0.215277777777778	1.78256885828521	0.000912461977554855	0.00660422175218057
GO:0061749	forked DNA-dependent helicase activity	14/2251	47/18639	0.297872340425532	2.46647825552709	0.000952814646172829	0.00679990731477775
GO:1990518	single-stranded 3'-5' DNA helicase activity	14/2251	47/18639	0.297872340425532	2.46647825552709	0.000952814646172829	0.00679990731477775
GO:0003779	actin binding	76/2251	443/18639	0.171557562076749	1.42055148802689	0.000956684516906389	0.00679990731477775
GO:0035198	miRNA binding	13/2251	42/18639	0.30952380952381	2.56295614647458	0.00096449434073121	0.0068146118002854
GO:0042809	nuclear vitamin D receptor binding	7/2251	15/18639	0.466666666666667	3.86414926699245	0.000987344193850652	0.00693477845030014
GO:0141052	histone H3 demethylase activity	10/2251	28/18639	0.357142857142857	2.95725709208606	0.00107974206126287	0.00753914015717074
GO:0140296	general transcription initiation factor binding	15/2251	53/18639	0.283018867924528	2.34348675221914	0.00114180799354563	0.00792588355753603
GO:0019956	chemokine binding	11/2251	33/18639	0.333333333333333	2.76010661928032	0.00118699794669748	0.00804561342681318
GO:0140416	transcription regulator inhibitor activity	11/2251	33/18639	0.333333333333333	2.76010661928032	0.00118699794669748	0.00804561342681318
GO:0009378	four-way junction helicase activity	14/2251	48/18639	0.291666666666667	2.41509329187028	0.00119767173241027	0.00804561342681318
GO:0036121	double-stranded DNA helicase activity	14/2251	48/18639	0.291666666666667	2.41509329187028	0.00119767173241027	0.00804561342681318
GO:0043138	3'-5' DNA helicase activity	14/2251	48/18639	0.291666666666667	2.41509329187028	0.00119767173241027	0.00804561342681318
GO:0004725	protein tyrosine phosphatase activity	23/2251	98/18639	0.23469387755102	1.94334037479941	0.00119972500130239	0.00804561342681318
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	28/2251	128/18639	0.21875	1.81131996890271	0.00121860892426997	0.00812634153431715
GO:0005085	guanyl-nucleotide exchange factor activity	44/2251	230/18639	0.191304347826087	1.58406119019566	0.00128092133581384	0.00846024041836818
GO:0043998	histone H2A acetyltransferase activity	9/2251	24/18639	0.375	3.10511994669036	0.00128293452005583	0.00846024041836818
GO:0005095	GTPase inhibitor activity	6/2251	12/18639	0.5	4.14015992892048	0.00148805756827466	0.00949636738463453
GO:0035259	nuclear glucocorticoid receptor binding	6/2251	12/18639	0.5	4.14015992892048	0.00148805756827466	0.00949636738463453
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/2251	12/18639	0.5	4.14015992892048	0.00148805756827466	0.00949636738463453
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/2251	12/18639	0.5	4.14015992892048	0.00148805756827466	0.00949636738463453
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/2251	12/18639	0.5	4.14015992892048	0.00148805756827466	0.00949636738463453
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/2251	12/18639	0.5	4.14015992892048	0.00148805756827466	0.00949636738463453
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	7/2251	16/18639	0.4375	3.62263993780542	0.00157320104272349	0.00998604084338386
GO:0043015	gamma-tubulin binding	11/2251	35/18639	0.314285714285714	2.60238624103573	0.00203707893813344	0.012861769678534
GO:0019210	kinase inhibitor activity	21/2251	90/18639	0.233333333333333	1.93207463349622	0.00207130823230915	0.0130086924431268
GO:0016407	acetyltransferase activity	22/2251	96/18639	0.229166666666667	1.89757330075522	0.0020985855599746	0.0130500651463144
GO:0004843	cysteine-type deubiquitinase activity	24/2251	108/18639	0.222222222222222	1.84007107952021	0.00210452845432596	0.0130500651463144
GO:0009931	calcium-dependent protein serine/threonine kinase activity	8/2251	21/18639	0.380952380952381	3.15440756489179	0.00212187242901321	0.0130500651463144
GO:0051010	microtubule plus-end binding	8/2251	21/18639	0.380952380952381	3.15440756489179	0.00212187242901321	0.0130500651463144
GO:0043539	protein serine/threonine kinase activator activity	18/2251	73/18639	0.246575342465753	2.04172270467311	0.002196089308866	0.0134368969568244
GO:0101005	deubiquitinase activity	25/2251	115/18639	0.217391304347826	1.80006953431325	0.002368125914731	0.0144152074912087
GO:0046965	nuclear retinoid X receptor binding	7/2251	17/18639	0.411764705882353	3.40954347087569	0.00239762239934172	0.0145202948368297
GO:0070412	R-SMAD binding	9/2251	26/18639	0.346153846153846	2.86626456617572	0.00245013107309936	0.0147329737276033
GO:0005035	death receptor activity	6/2251	13/18639	0.461538461538462	3.82168608823429	0.00248238815966357	0.0147329737276033
GO:0046974	histone H3K9 methyltransferase activity	6/2251	13/18639	0.461538461538462	3.82168608823429	0.00248238815966357	0.0147329737276033
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	6/2251	13/18639	0.461538461538462	3.82168608823429	0.00248238815966357	0.0147329737276033
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	12/2251	41/18639	0.292682926829268	2.4235082510754	0.00254892968473486	0.0150526345063695
GO:0031491	nucleosome binding	18/2251	74/18639	0.243243243243243	2.01413185731267	0.00258057915906142	0.0151640963455738
GO:0002039	p53 binding	17/2251	69/18639	0.246376811594203	2.04007880555502	0.0029019663219909	0.0164043799462479
GO:0032931	histone H3K56 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0043992	histone H3K9 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0043993	histone H3K18 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0043994	histone H3K23 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0043999	histone H2AK5 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0044012	histone H2AK9 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0044014	histone H2BK5 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0044015	histone H2BK12 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0044016	histone H3K4 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0044017	histone H3K27 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0044018	histone H3K36 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0046972	histone H4K16 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0140908	histone H3K122 acetyltransferase activity	8/2251	22/18639	0.363636363636364	3.01102540285126	0.00298512726907291	0.0164043799462479
GO:0061980	regulatory RNA binding	15/2251	58/18639	0.258620689655172	2.14146203220025	0.00303827485617632	0.0166195034759507
GO:0004721	phosphoprotein phosphatase activity	34/2251	175/18639	0.194285714285714	1.60874785809482	0.00331370505000552	0.0180429719924612
GO:0051018	protein kinase A binding	14/2251	53/18639	0.264150943396226	2.1872543020712	0.00334572447694835	0.0181341322106744
GO:0097110	scaffold protein binding	17/2251	70/18639	0.242857142857143	2.01093482261852	0.00341003150980049	0.0183986700096963
GO:0003924	GTPase activity	57/2251	331/18639	0.172205438066465	1.42591610844995	0.00355102377528506	0.019072693308884
GO:0036002	pre-mRNA binding	15/2251	59/18639	0.254237288135593	2.10516606555279	0.00362782318985533	0.0193974149835958
GO:0051015	actin filament binding	39/2251	209/18639	0.186602870813397	1.5451314567263	0.00366790912691808	0.0195238032899182
GO:0051880	G-quadruplex DNA binding	5/2251	10/18639	0.5	4.14015992892048	0.00381213070322647	0.0202008890389724
GO:0034236	protein kinase A catalytic subunit binding	6/2251	14/18639	0.428571428571429	3.54870851050327	0.00390342382505094	0.0205016109749357
GO:0071933	Arp2/3 complex binding	6/2251	14/18639	0.428571428571429	3.54870851050327	0.00390342382505094	0.0205016109749357
GO:0042162	telomeric DNA binding	11/2251	38/18639	0.289473684210526	2.3969346956908	0.0041776891864267	0.0218454496224163
GO:0060590	ATPase regulator activity	13/2251	49/18639	0.26530612244898	2.19681955412107	0.00443097645175919	0.0230682852992902
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	78/2251	484/18639	0.161157024793388	1.33443171262726	0.00465682689574985	0.0241382250011139
GO:0004860	protein kinase inhibitor activity	19/2251	84/18639	0.226190476190476	1.8729294916545	0.00475243772587636	0.0245267112200662
GO:0043014	alpha-tubulin binding	12/2251	44/18639	0.272727272727273	2.25826905213844	0.00483069964450339	0.0248226860520586
GO:0051087	protein-folding chaperone binding	27/2251	134/18639	0.201492537313433	1.66842265792318	0.00498320180226257	0.0254542480456916
GO:1990380	K48-linked deubiquitinase activity	7/2251	19/18639	0.368421052631579	3.05064415815193	0.00499649519346769	0.0254542480456916
GO:0030332	cyclin binding	10/2251	34/18639	0.294117647058824	2.43538819348264	0.00548083375596211	0.0276961854195921
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/2251	24/18639	0.333333333333333	2.76010661928032	0.00550657098485571	0.0276961854195921
GO:0050699	WW domain binding	8/2251	24/18639	0.333333333333333	2.76010661928032	0.00550657098485571	0.0276961854195921
GO:0106222	lncRNA binding	9/2251	29/18639	0.310344827586207	2.5697544386403	0.00561881324161052	0.0281414823535514
GO:0004857	enzyme inhibitor activity	68/2251	416/18639	0.163461538461538	1.35351382291631	0.00565362288274077	0.0281968502597197
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	6/2251	15/18639	0.4	3.31212794313638	0.0058474769125178	0.0288006435483761
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	6/2251	15/18639	0.4	3.31212794313638	0.0058474769125178	0.0288006435483761
GO:0061578	K63-linked deubiquitinase activity	6/2251	15/18639	0.4	3.31212794313638	0.0058474769125178	0.0288006435483761
GO:0003678	DNA helicase activity	17/2251	74/18639	0.22972972972973	1.90223564301752	0.00622978151241215	0.0305568208893935
GO:0140031	phosphorylation-dependent protein binding	5/2251	11/18639	0.454545454545455	3.76378175356407	0.00629845277013754	0.0306404239268576
GO:0140537	transcription regulator activator activity	5/2251	11/18639	0.454545454545455	3.76378175356407	0.00629845277013754	0.0306404239268576
GO:0004532	RNA exonuclease activity	11/2251	40/18639	0.275	2.27708796090626	0.00639919038087332	0.0308773942361652
GO:0032451	demethylase activity	11/2251	40/18639	0.275	2.27708796090626	0.00639919038087332	0.0308773942361652
GO:0001216	DNA-binding transcription activator activity	78/2251	491/18639	0.158859470468432	1.31540722792586	0.00668683973544966	0.0321347318460678
GO:0001618	virus receptor activity	18/2251	81/18639	0.222222222222222	1.84007107952021	0.00714897105219113	0.0341830584233797
GO:0044183	protein folding chaperone	17/2251	75/18639	0.226666666666667	1.87687250111062	0.00717066684702743	0.0341830584233797
GO:0042287	MHC protein binding	11/2251	41/18639	0.268292682926829	2.22154923015245	0.0078109526361241	0.0370864031163173
GO:0016410	N-acyltransferase activity	20/2251	94/18639	0.212765957446809	1.76177018251935	0.00785331465312017	0.0371389820448352
GO:0017116	single-stranded DNA helicase activity	14/2251	58/18639	0.241379310344828	1.99869789672023	0.00793518928983284	0.0373772606628237
GO:0140272	exogenous protein binding	18/2251	82/18639	0.219512195121951	1.81763118830655	0.0081510374062606	0.038242218977199
GO:0005521	lamin binding	6/2251	16/18639	0.375	3.10511994669036	0.00841204243439441	0.0393113951560085
GO:0005246	calcium channel regulator activity	13/2251	53/18639	0.245283018867925	2.03102185192325	0.00898072926046172	0.0418044142437963
GO:0004713	protein tyrosine kinase activity	27/2251	140/18639	0.192857142857143	1.59691882972647	0.0090630341085583	0.0420227401830418
GO:0005516	calmodulin binding	37/2251	207/18639	0.178743961352657	1.48005717265756	0.0092369166349853	0.0425492194149073
GO:0035613	RNA stem-loop binding	7/2251	21/18639	0.333333333333333	2.76010661928032	0.0092841177998829	0.0425492194149073
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/2251	21/18639	0.333333333333333	2.76010661928032	0.0092841177998829	0.0425492194149073
GO:0008603	cAMP-dependent protein kinase regulator activity	5/2251	12/18639	0.416666666666667	3.4501332741004	0.00973444934289674	0.0442712313027526
GO:0035497	cAMP response element binding	5/2251	12/18639	0.416666666666667	3.4501332741004	0.00973444934289674	0.0442712313027526
GO:0004527	exonuclease activity	18/2251	84/18639	0.214285714285714	1.77435425525163	0.0104932368257404	0.0475399698937169
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	14/2251	60/18639	0.233333333333333	1.93207463349622	0.0107871047550783	0.0486855260238705
GO:0042379	chemokine receptor binding	16/2251	72/18639	0.222222222222222	1.84007107952021	0.0108290600715432	0.0486897511550067
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/2251	43/18639	0.255813953488372	2.11822135898257	0.0113491010250561	0.0506442966794796
GO:0048156	tau protein binding	11/2251	43/18639	0.255813953488372	2.11822135898257	0.0113491010250561	0.0506442966794796
GO:0032183	SUMO binding	6/2251	17/18639	0.352941176470588	2.92246583217916	0.0116926351807868	0.0517879028343056
GO:1990226	histone methyltransferase binding	6/2251	17/18639	0.352941176470588	2.92246583217916	0.0116926351807868	0.0517879028343056
GO:0016763	pentosyltransferase activity	12/2251	49/18639	0.244897959183673	2.0278334345733	0.0119696764274092	0.0528178658711327
GO:0042054	histone methyltransferase activity	15/2251	67/18639	0.223880597014925	1.85380295324798	0.0124810542533967	0.0548704125880809
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	10/2251	38/18639	0.263157894736842	2.17903154153709	0.0126248963241667	0.0552979776265163
GO:0001046	core promoter sequence-specific DNA binding	11/2251	44/18639	0.25	2.07007996446024	0.0135219014852403	0.0590091803786039
GO:0097718	disordered domain specific binding	8/2251	28/18639	0.285714285714286	2.36580567366885	0.0150112475932837	0.0652686845905777
GO:0019003	GDP binding	16/2251	75/18639	0.213333333333333	1.7664682363394	0.0159095233561093	0.0689219132251887
GO:0008009	chemokine activity	11/2251	45/18639	0.244444444444444	2.02407818747223	0.0159950373173865	0.0690403974390465
GO:0030544	Hsp70 protein binding	12/2251	51/18639	0.235294117647059	1.94831055478611	0.0164247554419435	0.0706383503970542
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	17/2251	82/18639	0.207317073170732	1.71665167784508	0.0173882383940303	0.074512054056729
GO:0004177	aminopeptidase activity	10/2251	40/18639	0.25	2.07007996446024	0.0181159981387533	0.0759847695784459
GO:0030331	nuclear estrogen receptor binding	10/2251	40/18639	0.25	2.07007996446024	0.0181159981387533	0.0759847695784459
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	10/2251	40/18639	0.25	2.07007996446024	0.0181159981387533	0.0759847695784459
GO:0061791	GTPase motor activity	10/2251	40/18639	0.25	2.07007996446024	0.0181159981387533	0.0759847695784459
GO:0140662	ATP-dependent protein folding chaperone	10/2251	40/18639	0.25	2.07007996446024	0.0181159981387533	0.0759847695784459
GO:1990606	membrane scission GTPase motor activity	10/2251	40/18639	0.25	2.07007996446024	0.0181159981387533	0.0759847695784459
GO:0035401	histone H3Y41 kinase activity	22/2251	115/18639	0.191304347826087	1.58406119019566	0.0188482191364757	0.0785011793508655
GO:0140801	histone H2AXY142 kinase activity	22/2251	115/18639	0.191304347826087	1.58406119019566	0.0188482191364757	0.0785011793508655
GO:0005080	protein kinase C binding	12/2251	52/18639	0.230769230769231	1.91084304411714	0.0190726145917787	0.0788822073882973
GO:0030159	signaling receptor complex adaptor activity	12/2251	52/18639	0.230769230769231	1.91084304411714	0.0190726145917787	0.0788822073882973
GO:0019957	C-C chemokine binding	7/2251	24/18639	0.291666666666667	2.41509329187028	0.020007855707872	0.081123238241538
GO:0048027	mRNA 5'-UTR binding	7/2251	24/18639	0.291666666666667	2.41509329187028	0.020007855707872	0.081123238241538
GO:0070840	dynein complex binding	7/2251	24/18639	0.291666666666667	2.41509329187028	0.020007855707872	0.081123238241538
GO:0005545	1-phosphatidylinositol binding	5/2251	14/18639	0.357142857142857	2.95725709208606	0.0200245230031766	0.081123238241538
GO:0042043	neurexin family protein binding	5/2251	14/18639	0.357142857142857	2.95725709208606	0.0200245230031766	0.081123238241538
GO:0098847	sequence-specific single stranded DNA binding	5/2251	14/18639	0.357142857142857	2.95725709208606	0.0200245230031766	0.081123238241538
GO:0000175	3'-5'-RNA exonuclease activity	9/2251	35/18639	0.257142857142857	2.12922510630196	0.0203919636453839	0.0823308192077235
GO:0043495	protein-membrane adaptor activity	11/2251	47/18639	0.234042553191489	1.93794720077129	0.0219347409198667	0.0882594490572265
GO:1990782	protein tyrosine kinase binding	22/2251	117/18639	0.188034188034188	1.55698322113249	0.0226667824750654	0.0908968608037252
GO:0005525	GTP binding	59/2251	378/18639	0.156084656084656	1.29243087728205	0.0230271814805796	0.0920311933247407
GO:0035091	phosphatidylinositol binding	46/2251	284/18639	0.161971830985915	1.34117856852354	0.0231179011211029	0.0920837202374132
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0005131	growth hormone receptor binding	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0008140	cAMP response element binding protein binding	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0008239	dipeptidyl-peptidase activity	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0030957	Tat protein binding	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0031996	thioesterase binding	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0042975	peroxisome proliferator activated receptor binding	4/2251	10/18639	0.4	3.31212794313638	0.0244252565530201	0.09443902126526
GO:0008139	nuclear localization sequence binding	7/2251	25/18639	0.28	2.31848956019547	0.0249674275149676	0.096221871624242
GO:0017069	snRNA binding	12/2251	54/18639	0.222222222222222	1.84007107952021	0.0253046349526644	0.0972058307081315
GO:0043024	ribosomal small subunit binding	6/2251	20/18639	0.3	2.48409595735229	0.0266968283719125	0.102223017024065
GO:0120283	protein serine/threonine kinase binding	5/2251	15/18639	0.333333333333333	2.76010661928032	0.0271130460485061	0.103482912088671
GO:0001637	G protein-coupled chemoattractant receptor activity	7/2251	26/18639	0.269230769230769	2.22931688480334	0.0307064715906035	0.115656487103648
GO:0004950	chemokine receptor activity	7/2251	26/18639	0.269230769230769	2.22931688480334	0.0307064715906035	0.115656487103648
GO:0034237	protein kinase A regulatory subunit binding	7/2251	26/18639	0.269230769230769	2.22931688480334	0.0307064715906035	0.115656487103648
GO:0033192	calmodulin-dependent protein phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0140791	histone H2AXS140 phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/2251	81/18639	0.197530864197531	1.6356187373513	0.0313743798208716	0.115656487103648
GO:0051082	unfolded protein binding	22/2251	121/18639	0.181818181818182	1.50551270142563	0.032062404168761	0.117826853709967
GO:0048020	CCR chemokine receptor binding	11/2251	50/18639	0.22	1.82167036872501	0.0336580908330976	0.123309116724959
GO:0008276	protein methyltransferase activity	18/2251	95/18639	0.189473684210526	1.56890270990671	0.0342904220748577	0.12523917231648
GO:0016279	protein-lysine N-methyltransferase activity	14/2251	69/18639	0.202898550724638	1.68006489869237	0.0344571158235473	0.125461952400462
GO:0033549	MAP kinase phosphatase activity	16/2251	82/18639	0.195121951219512	1.6156721673836	0.0347649595607119	0.125495232766031
GO:0008432	JUN kinase binding	4/2251	11/18639	0.363636363636364	3.01102540285126	0.0347834301432387	0.125495232766031
GO:0019864	IgG binding	4/2251	11/18639	0.363636363636364	3.01102540285126	0.0347834301432387	0.125495232766031
GO:0017070	U6 snRNA binding	5/2251	16/18639	0.3125	2.5875999555753	0.0356135022367386	0.127328997454846
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2251	16/18639	0.3125	2.5875999555753	0.0356135022367386	0.127328997454846
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	5/2251	16/18639	0.3125	2.5875999555753	0.0356135022367386	0.127328997454846
GO:0044325	transmembrane transporter binding	24/2251	136/18639	0.176470588235294	1.46123291608958	0.0357845920355431	0.127556488727296
GO:1901981	phosphatidylinositol phosphate binding	31/2251	185/18639	0.167567567567568	1.38751305725984	0.0365062025937579	0.129739109217936
GO:0016504	peptidase activator activity	12/2251	57/18639	0.210526315789474	1.74322523322968	0.0372635482933879	0.132035318878363
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/2251	83/18639	0.192771084337349	1.59620623765609	0.0384148398296704	0.135459558721148
GO:0016278	lysine N-methyltransferase activity	14/2251	70/18639	0.2	1.65606397156819	0.0384581897969898	0.135459558721148
GO:0016791	phosphatase activity	43/2251	273/18639	0.157509157509158	1.30422620471488	0.0409391049457181	0.143771353759075
GO:0004407	histone deacetylase activity	6/2251	22/18639	0.272727272727273	2.25826905213844	0.0417012623081482	0.14473508292331
GO:0033558	protein lysine deacetylase activity	6/2251	22/18639	0.272727272727273	2.25826905213844	0.0417012623081482	0.14473508292331
GO:0050321	tau-protein kinase activity	6/2251	22/18639	0.272727272727273	2.25826905213844	0.0417012623081482	0.14473508292331
GO:0140517	protein-RNA adaptor activity	6/2251	22/18639	0.272727272727273	2.25826905213844	0.0417012623081482	0.14473508292331
GO:0008408	3'-5' exonuclease activity	12/2251	58/18639	0.206896551724138	1.7131696257602	0.0420120081299305	0.145388494607077
GO:0017018	myosin phosphatase activity	16/2251	84/18639	0.19047619047619	1.5772037824459	0.0423332527397033	0.14565093044066
GO:0051117	ATPase binding	16/2251	84/18639	0.19047619047619	1.5772037824459	0.0423332527397033	0.14565093044066
GO:0005543	phospholipid binding	73/2251	497/18639	0.146881287726358	1.21622404350581	0.043577576957665	0.149498797250718
GO:0019001	guanyl nucleotide binding	60/2251	400/18639	0.15	1.24204797867614	0.0443210461761428	0.151175522445636
GO:0032561	guanyl ribonucleotide binding	60/2251	400/18639	0.15	1.24204797867614	0.0443210461761428	0.151175522445636
GO:0046875	ephrin receptor binding	7/2251	28/18639	0.25	2.07007996446024	0.0446865885183305	0.151985617682689
GO:0030291	protein serine/threonine kinase inhibitor activity	10/2251	46/18639	0.217391304347826	1.80006953431325	0.0448685359286535	0.152168434706605
GO:0008429	phosphatidylethanolamine binding	5/2251	17/18639	0.294117647058824	2.43538819348264	0.0455805301767186	0.153269374843527
GO:0051787	misfolded protein binding	5/2251	17/18639	0.294117647058824	2.43538819348264	0.0455805301767186	0.153269374843527
GO:0070403	NAD+ binding	5/2251	17/18639	0.294117647058824	2.43538819348264	0.0455805301767186	0.153269374843527
GO:0043022	ribosome binding	20/2251	112/18639	0.178571428571429	1.47862854604303	0.0466217486282881	0.156327727745136
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/2251	12/18639	0.333333333333333	2.76010661928032	0.0473079205434097	0.156856149958177
GO:0043047	single-stranded telomeric DNA binding	4/2251	12/18639	0.333333333333333	2.76010661928032	0.0473079205434097	0.156856149958177
GO:0097677	STAT family protein binding	4/2251	12/18639	0.333333333333333	2.76010661928032	0.0473079205434097	0.156856149958177
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2251	12/18639	0.333333333333333	2.76010661928032	0.0473079205434097	0.156856149958177
GO:0005158	insulin receptor binding	6/2251	23/18639	0.260869565217391	2.1600834411759	0.0508505380650269	0.167201076684728
GO:0016493	C-C chemokine receptor activity	6/2251	23/18639	0.260869565217391	2.1600834411759	0.0508505380650269	0.167201076684728
GO:0043274	phospholipase binding	6/2251	23/18639	0.260869565217391	2.1600834411759	0.0508505380650269	0.167201076684728
GO:0001530	lipopolysaccharide binding	9/2251	41/18639	0.219512195121951	1.81763118830655	0.0525137042537186	0.172192726378906
GO:0005154	epidermal growth factor receptor binding	8/2251	35/18639	0.228571428571429	1.89264453893508	0.0532998579415639	0.174289067153268
GO:0004706	JUN kinase kinase kinase activity	5/2251	18/18639	0.277777777777778	2.30008884940027	0.0570423282247961	0.184997933341074
GO:0008409	5'-3' exonuclease activity	5/2251	18/18639	0.277777777777778	2.30008884940027	0.0570423282247961	0.184997933341074
GO:0050811	GABA receptor binding	5/2251	18/18639	0.277777777777778	2.30008884940027	0.0570423282247961	0.184997933341074
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	10/2251	48/18639	0.208333333333333	1.7250666370502	0.0578091371498596	0.186973966749001
GO:0030971	receptor tyrosine kinase binding	15/2251	81/18639	0.185185185185185	1.53339256626684	0.0595149785739828	0.191968150998145
GO:0042578	phosphoric ester hydrolase activity	54/2251	363/18639	0.148760330578512	1.23178311934824	0.0610734046210438	0.194798478467241
GO:0035035	histone acetyltransferase binding	6/2251	24/18639	0.25	2.07007996446024	0.0611314321840784	0.194798478467241
GO:0032934	sterol binding	13/2251	68/18639	0.191176470588235	1.58300232576371	0.0614014427100166	0.194798478467241
GO:0019855	calcium channel inhibitor activity	4/2251	13/18639	0.307692307692308	2.54779072548953	0.061992779637184	0.194798478467241
GO:0043560	insulin receptor substrate binding	4/2251	13/18639	0.307692307692308	2.54779072548953	0.061992779637184	0.194798478467241
GO:0046975	histone H3K36 methyltransferase activity	4/2251	13/18639	0.307692307692308	2.54779072548953	0.061992779637184	0.194798478467241
GO:0051011	microtubule minus-end binding	4/2251	13/18639	0.307692307692308	2.54779072548953	0.061992779637184	0.194798478467241
GO:0097157	pre-mRNA intronic binding	4/2251	13/18639	0.307692307692308	2.54779072548953	0.061992779637184	0.194798478467241
GO:0140666	annealing activity	4/2251	13/18639	0.307692307692308	2.54779072548953	0.061992779637184	0.194798478467241
GO:0001965	G-protein alpha-subunit binding	7/2251	30/18639	0.233333333333333	1.93207463349622	0.0621976607742917	0.194798478467241
GO:0051721	protein phosphatase 2A binding	7/2251	30/18639	0.233333333333333	1.93207463349622	0.0621976607742917	0.194798478467241
GO:0035254	glutamate receptor binding	10/2251	49/18639	0.204081632653061	1.68986119547775	0.0651070438669911	0.203373844921364
GO:0004722	protein serine/threonine phosphatase activity	18/2251	103/18639	0.174757281553398	1.44704618874891	0.0676478637112296	0.210755942848372
GO:0008375	acetylglucosaminyltransferase activity	9/2251	43/18639	0.209302325581395	1.73309020280392	0.0680633693593897	0.211495338820931
GO:0008574	plus-end-directed microtubule motor activity	5/2251	19/18639	0.263157894736842	2.17903154153709	0.070001448782503	0.216949659803736
GO:0043394	proteoglycan binding	8/2251	37/18639	0.216216216216216	1.79033942872237	0.0705954624312238	0.218220869546517
GO:0003774	cytoskeletal motor activity	25/2251	153/18639	0.163398692810458	1.35299344082369	0.0710232634633117	0.218973022677795
GO:0004175	endopeptidase activity	59/2251	405/18639	0.145679012345679	1.20626881879658	0.0723234403699845	0.221955674349014
GO:0019211	phosphatase activator activity	6/2251	25/18639	0.24	1.98727676588183	0.0725516441848503	0.221955674349014
GO:0120020	cholesterol transfer activity	6/2251	25/18639	0.24	1.98727676588183	0.0725516441848503	0.221955674349014
GO:0005178	integrin binding	26/2251	161/18639	0.161490683229814	1.33719451120413	0.0746652225842061	0.227834496677256
GO:0001223	transcription coactivator binding	9/2251	44/18639	0.204545454545455	1.69370178910383	0.0768114437950996	0.233782522525085
GO:0008191	metalloendopeptidase inhibitor activity	4/2251	14/18639	0.285714285714286	2.36580567366885	0.078780082290787	0.237943912669629
GO:0008494	translation activator activity	4/2251	14/18639	0.285714285714286	2.36580567366885	0.078780082290787	0.237943912669629
GO:0070742	C2H2 zinc finger domain binding	4/2251	14/18639	0.285714285714286	2.36580567366885	0.078780082290787	0.237943912669629
GO:0031369	translation initiation factor binding	7/2251	32/18639	0.21875	1.81131996890271	0.0833560465164924	0.24860207842984
GO:0051059	NF-kappaB binding	7/2251	32/18639	0.21875	1.81131996890271	0.0833560465164924	0.24860207842984
GO:0071813	lipoprotein particle binding	7/2251	32/18639	0.21875	1.81131996890271	0.0833560465164924	0.24860207842984
GO:0071814	protein-lipid complex binding	7/2251	32/18639	0.21875	1.81131996890271	0.0833560465164924	0.24860207842984
GO:0120015	sterol transfer activity	7/2251	32/18639	0.21875	1.81131996890271	0.0833560465164924	0.24860207842984
GO:0016004	phospholipase activator activity	5/2251	20/18639	0.25	2.07007996446024	0.0844363222526999	0.250049177248091
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/2251	26/18639	0.230769230769231	1.91084304411714	0.0851051959631243	0.250049177248091
GO:0008157	protein phosphatase 1 binding	6/2251	26/18639	0.230769230769231	1.91084304411714	0.0851051959631243	0.250049177248091
GO:0043548	phosphatidylinositol 3-kinase binding	6/2251	26/18639	0.230769230769231	1.91084304411714	0.0851051959631243	0.250049177248091
GO:0052742	phosphatidylinositol kinase activity	6/2251	26/18639	0.230769230769231	1.91084304411714	0.0851051959631243	0.250049177248091
GO:0070006	metalloaminopeptidase activity	6/2251	26/18639	0.230769230769231	1.91084304411714	0.0851051959631243	0.250049177248091
GO:0120013	lipid transfer activity	12/2251	65/18639	0.184615384615385	1.52867443529372	0.0871802769539679	0.25551355245521
GO:0004540	RNA nuclease activity	20/2251	121/18639	0.165289256198347	1.36864791038694	0.0895627538901142	0.261849726274792
GO:0051213	dioxygenase activity	16/2251	93/18639	0.172043010752688	1.42457115833823	0.0909013305817688	0.265110268797444
GO:0002020	protease binding	22/2251	136/18639	0.161764705882353	1.33946350641545	0.09353202532647	0.272114005055196
GO:0030276	clathrin binding	9/2251	46/18639	0.195652173913043	1.62006258088193	0.096271488239377	0.279399160244842
GO:0050700	CARD domain binding	4/2251	15/18639	0.266666666666667	2.20808529542426	0.0975680954697982	0.281100313889928
GO:0141050	histone H3K deacetylase activity	4/2251	15/18639	0.266666666666667	2.20808529542426	0.0975680954697982	0.281100313889928
GO:0141051	histone H4K deacetylase activity	4/2251	15/18639	0.266666666666667	2.20808529542426	0.0975680954697982	0.281100313889928
GO:0005123	death receptor binding	5/2251	21/18639	0.238095238095238	1.97150472805737	0.100303325268942	0.287584654816991
GO:0072542	protein phosphatase activator activity	5/2251	21/18639	0.238095238095238	1.97150472805737	0.100303325268942	0.287584654816991
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	11/2251	60/18639	0.183333333333333	1.51805864060418	0.102501847521029	0.29195772238734
GO:0098531	ligand-modulated transcription factor activity	11/2251	60/18639	0.183333333333333	1.51805864060418	0.102501847521029	0.29195772238734
GO:0003823	antigen binding	27/2251	174/18639	0.155172413793103	1.28487721932015	0.102566445017288	0.29195772238734
GO:0003925	G protein activity	10/2251	54/18639	0.185185185185185	1.53339256626684	0.110126989561387	0.305798462547168
GO:0008190	eukaryotic initiation factor 4E binding	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0043208	glycosphingolipid binding	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0043422	protein kinase B binding	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0051864	histone H3K36 demethylase activity	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0070513	death domain binding	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0098505	G-rich strand telomeric DNA binding	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0140999	histone H3K4 trimethyltransferase activity	3/2251	10/18639	0.3	2.48409595735229	0.110262630134952	0.305798462547168
GO:0140098	catalytic activity, acting on RNA	55/2251	387/18639	0.142118863049096	1.17678964387921	0.11208708001102	0.309531246365586
GO:0015026	coreceptor activity	11/2251	61/18639	0.180327868852459	1.49317243338116	0.112130106097053	0.309531246365586
GO:0019789	SUMO transferase activity	6/2251	28/18639	0.214285714285714	1.77435425525163	0.113523886239361	0.311927900384541
GO:0046625	sphingolipid binding	6/2251	28/18639	0.214285714285714	1.77435425525163	0.113523886239361	0.311927900384541
GO:0042169	SH2 domain binding	8/2251	41/18639	0.195121951219512	1.6156721673836	0.114310583205756	0.313364116085987
GO:0061133	endopeptidase activator activity	5/2251	22/18639	0.227272727272727	1.88189087678204	0.117539226139764	0.320380586100147
GO:0070034	telomerase RNA binding	5/2251	22/18639	0.227272727272727	1.88189087678204	0.117539226139764	0.320380586100147
GO:0008142	oxysterol binding	4/2251	16/18639	0.25	2.07007996446024	0.118219626547485	0.320380586100147
GO:0022858	alanine transmembrane transporter activity	4/2251	16/18639	0.25	2.07007996446024	0.118219626547485	0.320380586100147
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2251	16/18639	0.25	2.07007996446024	0.118219626547485	0.320380586100147
GO:0061631	ubiquitin conjugating enzyme activity	7/2251	35/18639	0.2	1.65606397156819	0.121851686128449	0.329471415568268
GO:0051879	Hsp90 protein binding	8/2251	42/18639	0.19047619047619	1.5772037824459	0.127097384509636	0.342874080483949
GO:0008170	N-methyltransferase activity	16/2251	98/18639	0.163265306122449	1.3518889563822	0.128975920034361	0.347152873199063
GO:0051861	glycolipid binding	6/2251	29/18639	0.206896551724138	1.7131696257602	0.129315265547564	0.34727877874425
GO:0034713	type I transforming growth factor beta receptor binding	3/2251	11/18639	0.272727272727273	2.25826905213844	0.138567330131844	0.368787939162554
GO:0043522	leucine zipper domain binding	3/2251	11/18639	0.272727272727273	2.25826905213844	0.138567330131844	0.368787939162554
GO:0070990	snRNP binding	3/2251	11/18639	0.272727272727273	2.25826905213844	0.138567330131844	0.368787939162554
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/2251	11/18639	0.272727272727273	2.25826905213844	0.138567330131844	0.368787939162554
GO:0003697	single-stranded DNA binding	19/2251	121/18639	0.15702479338843	1.30021551486759	0.139160394118878	0.369537780355946
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/2251	17/18639	0.235294117647059	1.94831055478611	0.14057011773849	0.369970575954739
GO:0019198	transmembrane receptor protein phosphatase activity	4/2251	17/18639	0.235294117647059	1.94831055478611	0.14057011773849	0.369970575954739
GO:0030169	low-density lipoprotein particle binding	4/2251	17/18639	0.235294117647059	1.94831055478611	0.14057011773849	0.369970575954739
GO:0045125	bioactive lipid receptor activity	4/2251	17/18639	0.235294117647059	1.94831055478611	0.14057011773849	0.369970575954739
GO:0005125	cytokine activity	34/2251	234/18639	0.145299145299145	1.20312339814783	0.145451242813483	0.381970409777887
GO:0005518	collagen binding	12/2251	72/18639	0.166666666666667	1.38005330964016	0.154333300816461	0.404400944964987
GO:0030552	cAMP binding	5/2251	24/18639	0.208333333333333	1.7250666370502	0.155782922119238	0.406228388791946
GO:0060229	lipase activator activity	5/2251	24/18639	0.208333333333333	1.7250666370502	0.155782922119238	0.406228388791946
GO:0005048	signal sequence binding	9/2251	51/18639	0.176470588235294	1.46123291608958	0.15605740967913	0.406228388791946
GO:0000900	mRNA regulatory element binding translation repressor activity	4/2251	18/18639	0.222222222222222	1.84007107952021	0.164435200456688	0.425238742793221
GO:0003746	translation elongation factor activity	4/2251	18/18639	0.222222222222222	1.84007107952021	0.164435200456688	0.425238742793221
GO:0070064	proline-rich region binding	4/2251	18/18639	0.222222222222222	1.84007107952021	0.164435200456688	0.425238742793221
GO:0008238	exopeptidase activity	16/2251	102/18639	0.156862745098039	1.29887370319074	0.165136036852941	0.425961732695751
GO:0004126	cytidine deaminase activity	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0005078	MAP-kinase scaffold activity	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0008179	adenylate cyclase binding	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0035197	siRNA binding	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0045295	gamma-catenin binding	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0070008	serine-type exopeptidase activity	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0070410	co-SMAD binding	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0070679	inositol 1,4,5 trisphosphate binding	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/2251	12/18639	0.25	2.07007996446024	0.168987133327989	0.425961732695751
GO:0004879	nuclear receptor activity	10/2251	59/18639	0.169491525423729	1.40344404370186	0.169021041364531	0.425961732695751
GO:0141110	transporter inhibitor activity	8/2251	45/18639	0.177777777777778	1.47205686361617	0.169585635238676	0.426479129297264
GO:0141108	transporter regulator activity	25/2251	170/18639	0.147058823529412	1.21769409674132	0.172841113565963	0.433747149688791
GO:0004709	MAP kinase kinase kinase activity	5/2251	25/18639	0.2	1.65606397156819	0.176590741602835	0.438521360423776
GO:0015662	P-type ion transporter activity	5/2251	25/18639	0.2	1.65606397156819	0.176590741602835	0.438521360423776
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/2251	25/18639	0.2	1.65606397156819	0.176590741602835	0.438521360423776
GO:0017025	TBP-class protein binding	5/2251	25/18639	0.2	1.65606397156819	0.176590741602835	0.438521360423776
GO:0140358	P-type transmembrane transporter activity	5/2251	25/18639	0.2	1.65606397156819	0.176590741602835	0.438521360423776
GO:0004518	nuclease activity	30/2251	209/18639	0.143540669856459	1.18856265902023	0.18022713583784	0.446617140374772
GO:0030515	snoRNA binding	6/2251	32/18639	0.1875	1.55255997334518	0.182364994485168	0.449102175215548
GO:0043425	bHLH transcription factor binding	6/2251	32/18639	0.1875	1.55255997334518	0.182364994485168	0.449102175215548
GO:0070717	poly-purine tract binding	6/2251	32/18639	0.1875	1.55255997334518	0.182364994485168	0.449102175215548
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/2251	53/18639	0.169811320754717	1.40609205133148	0.184078874596004	0.452384315000947
GO:0042800	histone H3K4 methyltransferase activity	4/2251	19/18639	0.210526315789474	1.74322523322968	0.18961753423647	0.465033084997294
GO:0061134	peptidase regulator activity	32/2251	226/18639	0.141592920353982	1.17243467013677	0.191933101301928	0.469741425248224
GO:0140223	general transcription initiation factor activity	11/2251	68/18639	0.161764705882353	1.33946350641545	0.192916471220019	0.471176648843957
GO:0001540	amyloid-beta binding	13/2251	83/18639	0.156626506024096	1.29691756809557	0.197716576053391	0.478819070289403
GO:0008135	translation factor activity, RNA binding	13/2251	83/18639	0.156626506024096	1.29691756809557	0.197716576053391	0.478819070289403
GO:0004529	DNA exonuclease activity	5/2251	26/18639	0.192307692307692	1.59236920343095	0.198373014374195	0.478819070289403
GO:0005160	transforming growth factor beta receptor binding	5/2251	26/18639	0.192307692307692	1.59236920343095	0.198373014374195	0.478819070289403
GO:0030507	spectrin binding	5/2251	26/18639	0.192307692307692	1.59236920343095	0.198373014374195	0.478819070289403
GO:0015485	cholesterol binding	9/2251	54/18639	0.166666666666667	1.38005330964016	0.198869251602928	0.478819070289403
GO:0051287	NAD binding	9/2251	54/18639	0.166666666666667	1.38005330964016	0.198869251602928	0.478819070289403
GO:0004535	poly(A)-specific ribonuclease activity	3/2251	13/18639	0.230769230769231	1.91084304411714	0.201085439435231	0.479294009256262
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2251	13/18639	0.230769230769231	1.91084304411714	0.201085439435231	0.479294009256262
GO:0019104	DNA N-glycosylase activity	3/2251	13/18639	0.230769230769231	1.91084304411714	0.201085439435231	0.479294009256262
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/2251	13/18639	0.230769230769231	1.91084304411714	0.201085439435231	0.479294009256262
GO:0140333	glycerophospholipid flippase activity	3/2251	13/18639	0.230769230769231	1.91084304411714	0.201085439435231	0.479294009256262
GO:0030296	protein tyrosine kinase activator activity	6/2251	33/18639	0.181818181818182	1.50551270142563	0.201712365625819	0.479824805606909
GO:0016779	nucleotidyltransferase activity	20/2251	136/18639	0.147058823529412	1.21769409674132	0.204965233228783	0.486587463685132
GO:0008013	beta-catenin binding	16/2251	106/18639	0.150943396226415	1.24985960118354	0.205998491234626	0.488064289611778
GO:0180051	translation factor activity	13/2251	84/18639	0.154761904761905	1.28147807323729	0.209826742892287	0.496144111181563
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	32/2251	229/18639	0.139737991266376	1.15707526397778	0.213512402568625	0.503855311826953
GO:0099106	ion channel regulator activity	23/2251	160/18639	0.14375	1.19029597956464	0.215766295052355	0.504504995659202
GO:0001614	purinergic nucleotide receptor activity	4/2251	20/18639	0.2	1.65606397156819	0.215912837232413	0.504504995659202
GO:0016502	nucleotide receptor activity	4/2251	20/18639	0.2	1.65606397156819	0.215912837232413	0.504504995659202
GO:0016505	peptidase activator activity involved in apoptotic process	4/2251	20/18639	0.2	1.65606397156819	0.215912837232413	0.504504995659202
GO:0042288	MHC class I protein binding	4/2251	20/18639	0.2	1.65606397156819	0.215912837232413	0.504504995659202
GO:0016247	channel regulator activity	24/2251	168/18639	0.142857142857143	1.18290283683442	0.218799125459636	0.510244718900958
GO:0061650	ubiquitin-like protein conjugating enzyme activity	7/2251	41/18639	0.170731707317073	1.41371314646065	0.220286042496999	0.512704965576348
GO:0035255	ionotropic glutamate receptor binding	5/2251	27/18639	0.185185185185185	1.53339256626684	0.221009372930213	0.513381850622629
GO:0005496	steroid binding	16/2251	108/18639	0.148148148148148	1.22671405301348	0.228021426162583	0.528635611044895
GO:0019212	phosphatase inhibitor activity	9/2251	56/18639	0.160714285714286	1.33076569143873	0.229848742639563	0.531833250512985
GO:0008174	mRNA methyltransferase activity	3/2251	14/18639	0.214285714285714	1.77435425525163	0.23444144592917	0.537223931115684
GO:0019763	immunoglobulin receptor activity	3/2251	14/18639	0.214285714285714	1.77435425525163	0.23444144592917	0.537223931115684
GO:0032454	histone H3K9 demethylase activity	3/2251	14/18639	0.214285714285714	1.77435425525163	0.23444144592917	0.537223931115684
GO:0044548	S100 protein binding	3/2251	14/18639	0.214285714285714	1.77435425525163	0.23444144592917	0.537223931115684
GO:0061665	SUMO ligase activity	3/2251	14/18639	0.214285714285714	1.77435425525163	0.23444144592917	0.537223931115684
GO:0016859	cis-trans isomerase activity	7/2251	42/18639	0.166666666666667	1.38005330964016	0.238923774094471	0.54644030799641
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/2251	21/18639	0.19047619047619	1.5772037824459	0.243115075341465	0.554956912365998
GO:0051959	dynein light intermediate chain binding	5/2251	28/18639	0.178571428571429	1.47862854604303	0.244375783080399	0.556764020185092
GO:0046982	protein heterodimerization activity	49/2251	369/18639	0.132791327913279	1.0995546694694	0.258864638618245	0.588644302758346
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/2251	36/18639	0.166666666666667	1.38005330964016	0.263641048923788	0.597217414260566
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/2251	36/18639	0.166666666666667	1.38005330964016	0.263641048923788	0.597217414260566
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/2251	29/18639	0.172413793103448	1.42764135480017	0.268346724233072	0.600563395605919
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2251	29/18639	0.172413793103448	1.42764135480017	0.268346724233072	0.600563395605919
GO:0097472	cyclin-dependent protein kinase activity	5/2251	29/18639	0.172413793103448	1.42764135480017	0.268346724233072	0.600563395605919
GO:0005041	low-density lipoprotein particle receptor activity	3/2251	15/18639	0.2	1.65606397156819	0.268659783544012	0.600563395605919
GO:0031386	protein tag activity	3/2251	15/18639	0.2	1.65606397156819	0.268659783544012	0.600563395605919
GO:0140776	protein-containing complex destabilizing activity	3/2251	15/18639	0.2	1.65606397156819	0.268659783544012	0.600563395605919
GO:0141047	molecular tag activity	3/2251	15/18639	0.2	1.65606397156819	0.268659783544012	0.600563395605919
GO:0030021	extracellular matrix structural constituent conferring compression resistance	4/2251	22/18639	0.181818181818182	1.50551270142563	0.27102081960851	0.604702467810716
GO:0016248	channel inhibitor activity	7/2251	44/18639	0.159090909090909	1.31732361374743	0.277583515952083	0.61818317717659
GO:0019213	deacetylase activity	6/2251	37/18639	0.162162162162162	1.34275457154178	0.285295864001537	0.634168896198173
GO:0008187	poly-pyrimidine tract binding	5/2251	30/18639	0.166666666666667	1.38005330964016	0.292797135731511	0.648414552450192
GO:0031624	ubiquitin conjugating enzyme binding	5/2251	30/18639	0.166666666666667	1.38005330964016	0.292797135731511	0.648414552450192
GO:0061135	endopeptidase regulator activity	25/2251	184/18639	0.135869565217391	1.12504345894578	0.295106535871354	0.652311839998692
GO:0000149	SNARE binding	15/2251	106/18639	0.141509433962264	1.17174337610957	0.296238873750161	0.653597663831674
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/2251	23/18639	0.173913043478261	1.4400556274506	0.299432810743758	0.6583330781792
GO:0003777	microtubule motor activity	10/2251	68/18639	0.147058823529412	1.21769409674132	0.302978424892176	0.6583330781792
GO:0005149	interleukin-1 receptor binding	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0005159	insulin-like growth factor receptor binding	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0008296	3'-5'-DNA exonuclease activity	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0030275	LRR domain binding	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0097027	ubiquitin-protein transferase activator activity	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0140327	flippase activity	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0140328	floppase activity	3/2251	16/18639	0.1875	1.55255997334518	0.303376742850904	0.6583330781792
GO:0004864	protein phosphatase inhibitor activity	8/2251	53/18639	0.150943396226415	1.24985960118354	0.306635248671207	0.664189854329786
GO:0019905	syntaxin binding	9/2251	61/18639	0.147540983606557	1.22168653640276	0.313740150121859	0.678341636055823
GO:0043178	alcohol binding	13/2251	92/18639	0.141304347826087	1.17004519730361	0.316496738662941	0.683057506896201
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2251	31/18639	0.161290322580645	1.33553546094209	0.317604120152755	0.683732491689157
GO:0140767	enzyme-substrate adaptor activity	19/2251	139/18639	0.136690647482014	1.13184228272646	0.317961529412312	0.683732491689157
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2251	54/18639	0.148148148148148	1.22671405301348	0.325377161204821	0.698413544936931
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2251	24/18639	0.166666666666667	1.38005330964016	0.328162788468662	0.700649449869908
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2251	24/18639	0.166666666666667	1.38005330964016	0.328162788468662	0.700649449869908
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	6/2251	39/18639	0.153846153846154	1.27389536274476	0.329605062357035	0.700649449869908
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2251	39/18639	0.153846153846154	1.27389536274476	0.329605062357035	0.700649449869908
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0005092	GDP-dissociation inhibitor activity	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0015278	intracellularly gated calcium channel activity	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0031489	myosin V binding	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0045236	CXCR chemokine receptor binding	3/2251	17/18639	0.176470588235294	1.46123291608958	0.338263876803563	0.700649449869908
GO:0000182	rDNA binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0001094	TFIID-class transcription factor complex binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0004382	GDP phosphatase activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0004955	prostaglandin receptor activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0005522	profilin binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0005528	FK506 binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0015279	store-operated calcium channel activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0035256	G protein-coupled glutamate receptor binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0050308	sugar-phosphatase activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0099122	RNA polymerase II C-terminal domain binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:1905394	retromer complex binding	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:1990757	ubiquitin ligase activator activity	2/2251	10/18639	0.2	1.65606397156819	0.3447171682595	0.700649449869908
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	22/2251	167/18639	0.131736526946108	1.09082058007486	0.365376562120423	0.741370904678534
GO:0004536	DNA nuclease activity	9/2251	64/18639	0.140625	1.16441998000889	0.36690725686492	0.743206337711025
GO:0019239	deaminase activity	5/2251	33/18639	0.151515151515152	1.25459391785469	0.367815552158427	0.743776934262441
GO:0008525	phosphatidylcholine transporter activity	3/2251	18/18639	0.166666666666667	1.38005330964016	0.373029612072938	0.750092273324576
GO:0030228	lipoprotein particle receptor activity	3/2251	18/18639	0.166666666666667	1.38005330964016	0.373029612072938	0.750092273324576
GO:0001664	G protein-coupled receptor binding	38/2251	297/18639	0.127946127946128	1.05943486396618	0.377179744961159	0.750092273324576
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2251	26/18639	0.153846153846154	1.27389536274476	0.385881043659098	0.750092273324576
GO:0005112	Notch binding	4/2251	26/18639	0.153846153846154	1.27389536274476	0.385881043659098	0.750092273324576
GO:0008143	poly(A) binding	4/2251	26/18639	0.153846153846154	1.27389536274476	0.385881043659098	0.750092273324576
GO:0019865	immunoglobulin binding	4/2251	26/18639	0.153846153846154	1.27389536274476	0.385881043659098	0.750092273324576
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0003953	NAD+ nucleosidase activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0004954	prostanoid receptor activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0005114	type II transforming growth factor beta receptor binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0005536	D-glucose binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0008172	S-methyltransferase activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0008199	ferric iron binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0008526	phosphatidylinositol transfer activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0010854	adenylate cyclase regulator activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0019203	carbohydrate phosphatase activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0019215	intermediate filament binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0032404	mismatch repair complex binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0032794	GTPase activating protein binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0048185	activin binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0050786	RAGE receptor binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0050998	nitric-oxide synthase binding	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0180030	inositol phosphate kinase activity	2/2251	11/18639	0.181818181818182	1.50551270142563	0.390528243398979	0.750092273324576
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	5/2251	34/18639	0.147058823529412	1.21769409674132	0.392996974277297	0.75239904591476
GO:0051427	hormone receptor binding	5/2251	34/18639	0.147058823529412	1.21769409674132	0.392996974277297	0.75239904591476
GO:0003684	damaged DNA binding	10/2251	74/18639	0.135135135135135	1.11896214295148	0.403484620217617	0.771233887597926
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/2251	19/18639	0.157894736842105	1.30741892492226	0.407419376667276	0.771302711489724
GO:0005520	insulin-like growth factor binding	3/2251	19/18639	0.157894736842105	1.30741892492226	0.407419376667276	0.771302711489724
GO:0008301	DNA binding, bending	3/2251	19/18639	0.157894736842105	1.30741892492226	0.407419376667276	0.771302711489724
GO:0043395	heparan sulfate proteoglycan binding	3/2251	19/18639	0.157894736842105	1.30741892492226	0.407419376667276	0.771302711489724
GO:0070003	threonine-type peptidase activity	3/2251	19/18639	0.157894736842105	1.30741892492226	0.407419376667276	0.771302711489724
GO:0097001	ceramide binding	3/2251	19/18639	0.157894736842105	1.30741892492226	0.407419376667276	0.771302711489724
GO:0008266	poly(U) RNA binding	4/2251	27/18639	0.148148148148148	1.22671405301348	0.414554377698904	0.783560583325795
GO:0034061	DNA polymerase activity	5/2251	35/18639	0.142857142857143	1.18290283683442	0.4180906911474	0.788988315408528
GO:0008200	ion channel inhibitor activity	6/2251	43/18639	0.13953488372093	1.15539346853595	0.419895159433157	0.790461134406673
GO:0003743	translation initiation factor activity	7/2251	51/18639	0.137254901960784	1.1365144902919	0.420736818597427	0.790461134406673
GO:0050840	extracellular matrix binding	9/2251	67/18639	0.134328358208955	1.11228177194879	0.42086894435132	0.790461134406673
GO:0000340	RNA 7-methylguanosine cap binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0003720	telomerase activity	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0005165	neurotrophin receptor binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0005527	macrolide binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0016208	AMP binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0016273	arginine N-methyltransferase activity	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0016274	protein-arginine N-methyltransferase activity	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0017166	vinculin binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0034452	dynactin binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:1990459	transferrin receptor binding	2/2251	12/18639	0.166666666666667	1.38005330964016	0.434836465413177	0.803973340257697
GO:0030145	manganese ion binding	9/2251	68/18639	0.132352941176471	1.09592468706719	0.438852243929833	0.808989666935386
GO:0001972	retinoic acid binding	3/2251	20/18639	0.15	1.24204797867614	0.441214648332253	0.808989666935386
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/2251	20/18639	0.15	1.24204797867614	0.441214648332253	0.808989666935386
GO:0061608	nuclear import signal receptor activity	3/2251	20/18639	0.15	1.24204797867614	0.441214648332253	0.808989666935386
GO:0005484	SNAP receptor activity	5/2251	36/18639	0.138888888888889	1.15004442470013	0.443001923764112	0.808989666935386
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2251	36/18639	0.138888888888889	1.15004442470013	0.443001923764112	0.808989666935386
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2251	36/18639	0.138888888888889	1.15004442470013	0.443001923764112	0.808989666935386
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2251	36/18639	0.138888888888889	1.15004442470013	0.443001923764112	0.808989666935386
GO:0030551	cyclic nucleotide binding	5/2251	37/18639	0.135135135135135	1.11896214295148	0.467643495602014	0.852677157111507
GO:0004629	phospholipase C activity	4/2251	29/18639	0.137931034482759	1.14211308384013	0.470848797213015	0.855889132734344
GO:0008373	sialyltransferase activity	3/2251	21/18639	0.142857142857143	1.18290283683442	0.474231243830717	0.855889132734344
GO:0070182	DNA polymerase binding	3/2251	21/18639	0.142857142857143	1.18290283683442	0.474231243830717	0.855889132734344
GO:0003964	RNA-directed DNA polymerase activity	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0004465	lipoprotein lipase activity	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0008035	high-density lipoprotein particle binding	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0031994	insulin-like growth factor I binding	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0035325	Toll-like receptor binding	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0070123	transforming growth factor beta receptor activity, type III	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0071837	HMG box domain binding	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0089720	caspase binding	2/2251	13/18639	0.153846153846154	1.27389536274476	0.477336651954621	0.855889132734344
GO:0004866	endopeptidase inhibitor activity	20/2251	161/18639	0.124223602484472	1.02861116246472	0.48243982761163	0.863734653657624
GO:0005200	structural constituent of cytoskeleton	14/2251	112/18639	0.125	1.03503998223012	0.488386643025865	0.873064676614008
GO:0000146	microfilament motor activity	5/2251	38/18639	0.131578947368421	1.08951577076855	0.491936076250376	0.876768952716511
GO:0043531	ADP binding	5/2251	38/18639	0.131578947368421	1.08951577076855	0.491936076250376	0.876768952716511
GO:0001968	fibronectin binding	4/2251	30/18639	0.133333333333333	1.10404264771213	0.498241360517862	0.886675404699703
GO:0048306	calcium-dependent protein binding	10/2251	80/18639	0.125	1.03503998223012	0.504709115866086	0.893013964398956
GO:0008093	cytoskeletal anchor activity	3/2251	22/18639	0.136363636363636	1.12913452606922	0.506317100286855	0.893013964398956
GO:0008970	phospholipase A1 activity	3/2251	22/18639	0.136363636363636	1.12913452606922	0.506317100286855	0.893013964398956
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	3/2251	22/18639	0.136363636363636	1.12913452606922	0.506317100286855	0.893013964398956
GO:0034062	5'-3' RNA polymerase activity	3/2251	22/18639	0.136363636363636	1.12913452606922	0.506317100286855	0.893013964398956
GO:0097747	RNA polymerase activity	3/2251	22/18639	0.136363636363636	1.12913452606922	0.506317100286855	0.893013964398956
GO:0000217	DNA secondary structure binding	5/2251	39/18639	0.128205128205128	1.06157946895397	0.515808284175867	0.8986131200714
GO:0005161	platelet-derived growth factor receptor binding	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0005344	oxygen carrier activity	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0008195	phosphatidate phosphatase activity	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0019992	diacylglycerol binding	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0030983	mismatched DNA binding	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0031404	chloride ion binding	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0043176	amine binding	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0098599	palmitoyl hydrolase activity	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:1990825	sequence-specific mRNA binding	2/2251	14/18639	0.142857142857143	1.18290283683442	0.517819186292197	0.8986131200714
GO:0008327	methyl-CpG binding	4/2251	31/18639	0.129032258064516	1.06842836875367	0.525002433164544	0.909748741848633
GO:0038187	pattern recognition receptor activity	6/2251	48/18639	0.125	1.03503998223012	0.529856931862839	0.916822417086283
GO:0038024	cargo receptor activity	8/2251	65/18639	0.123076923076923	1.01911629019581	0.533914423972258	0.92172564421047
GO:0003887	DNA-directed DNA polymerase activity	3/2251	23/18639	0.130434782608696	1.08004172058795	0.537349743718319	0.92172564421047
GO:0005283	amino acid:sodium symporter activity	3/2251	23/18639	0.130434782608696	1.08004172058795	0.537349743718319	0.92172564421047
GO:0016849	phosphorus-oxygen lyase activity	3/2251	23/18639	0.130434782608696	1.08004172058795	0.537349743718319	0.92172564421047
GO:0017134	fibroblast growth factor binding	3/2251	23/18639	0.130434782608696	1.08004172058795	0.537349743718319	0.92172564421047
GO:0140103	catalytic activity, acting on a glycoprotein	3/2251	23/18639	0.130434782608696	1.08004172058795	0.537349743718319	0.92172564421047
GO:0015036	disulfide oxidoreductase activity	5/2251	40/18639	0.125	1.03503998223012	0.539196667352712	0.923559082464168
GO:0016757	glycosyltransferase activity	32/2251	267/18639	0.119850187265918	0.992397885583935	0.546955068711675	0.935498078617807
GO:0140142	nucleocytoplasmic carrier activity	4/2251	32/18639	0.125	1.03503998223012	0.551053008947509	0.94115096636071
GO:0008235	metalloexopeptidase activity	8/2251	66/18639	0.121212121212121	1.00367513428375	0.551991072541556	0.941398567682223
GO:0000774	adenyl-nucleotide exchange factor activity	2/2251	15/18639	0.133333333333333	1.10404264771213	0.55615140209961	0.943073877560338
GO:0004953	icosanoid receptor activity	2/2251	15/18639	0.133333333333333	1.10404264771213	0.55615140209961	0.943073877560338
GO:0015929	hexosaminidase activity	2/2251	15/18639	0.133333333333333	1.10404264771213	0.55615140209961	0.943073877560338
GO:0050780	dopamine receptor binding	2/2251	15/18639	0.133333333333333	1.10404264771213	0.55615140209961	0.943073877560338
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/2251	41/18639	0.121951219512195	1.00979510461475	0.562045579784739	0.949001569280917
GO:0017080	sodium channel regulator activity	5/2251	41/18639	0.121951219512195	1.00979510461475	0.562045579784739	0.949001569280917
GO:0140318	protein transporter activity	5/2251	41/18639	0.121951219512195	1.00979510461475	0.562045579784739	0.949001569280917
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/2251	24/18639	0.125	1.03503998223012	0.56723359446827	0.955044364019627
GO:0070300	phosphatidic acid binding	3/2251	24/18639	0.125	1.03503998223012	0.56723359446827	0.955044364019627
GO:0030414	peptidase inhibitor activity	20/2251	169/18639	0.118343195266272	0.979919509803664	0.574256061906489	0.965498506349862
GO:0001786	phosphatidylserine binding	7/2251	59/18639	0.11864406779661	0.9824108305913	0.579724735008132	0.972978569778879
GO:0005319	lipid transporter activity	21/2251	178/18639	0.117977528089888	0.976891668621686	0.580344420727419	0.972978569778879
GO:0019838	growth factor binding	16/2251	136/18639	0.117647058823529	0.974155277393054	0.584169100399148	0.974283751066546
GO:0031492	nucleosomal DNA binding	5/2251	42/18639	0.119047619047619	0.985752364028685	0.584306970953839	0.974283751066546
GO:0042056	chemoattractant activity	5/2251	42/18639	0.119047619047619	0.985752364028685	0.584306970953839	0.974283751066546
GO:0008168	methyltransferase activity	24/2251	204/18639	0.117647058823529	0.974155277393054	0.587095834762557	0.974283751066546
GO:0005548	phospholipid transporter activity	8/2251	68/18639	0.117647058823529	0.974155277393054	0.587226090858003	0.974283751066546
GO:0003688	DNA replication origin binding	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0004707	MAP kinase activity	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0004708	MAP kinase kinase activity	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0005024	transforming growth factor beta receptor activity	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0043023	ribosomal large subunit binding	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0070411	I-SMAD binding	2/2251	16/18639	0.125	1.03503998223012	0.592262067706568	0.974283751066546
GO:0000287	magnesium ion binding	27/2251	230/18639	0.117391304347826	0.972037548529156	0.593356021090055	0.974283751066546
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/2251	25/18639	0.12	0.993638382940915	0.595897222640533	0.974283751066546
GO:0017056	structural constituent of nuclear pore	3/2251	25/18639	0.12	0.993638382940915	0.595897222640533	0.974283751066546
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/2251	25/18639	0.12	0.993638382940915	0.595897222640533	0.974283751066546
GO:0019707	protein-cysteine S-acyltransferase activity	3/2251	25/18639	0.12	0.993638382940915	0.595897222640533	0.974283751066546
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	10/2251	86/18639	0.116279069767442	0.962827890446623	0.600512448850069	0.979554080554802
GO:0008376	acetylgalactosaminyltransferase activity	4/2251	34/18639	0.117647058823529	0.974155277393054	0.600771163137233	0.979554080554802
GO:0008081	phosphoric diester hydrolase activity	10/2251	87/18639	0.114942528735632	0.95176090320011	0.615615129343211	0.999999999999999
GO:0070851	growth factor receptor binding	16/2251	139/18639	0.115107913669065	0.9531303433486	0.620429221666349	0.999999999999999
GO:0008198	ferrous iron binding	3/2251	26/18639	0.115384615384615	0.955421522058572	0.623290637290285	0.999999999999999
GO:0030247	polysaccharide binding	3/2251	26/18639	0.115384615384615	0.955421522058572	0.623290637290285	0.999999999999999
GO:0050750	low-density lipoprotein particle receptor binding	3/2251	26/18639	0.115384615384615	0.955421522058572	0.623290637290285	0.999999999999999
GO:0004659	prenyltransferase activity	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0016018	cyclosporin A binding	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0016805	dipeptidase activity	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0017110	nucleoside diphosphate phosphatase activity	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0032977	membrane insertase activity	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0036041	long-chain fatty acid binding	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0048038	quinone binding	2/2251	17/18639	0.117647058823529	0.974155277393054	0.626128493160302	0.999999999999999
GO:0016651	oxidoreductase activity, acting on NAD(P)H	10/2251	88/18639	0.113636363636364	0.940945438391018	0.630425588974735	0.999999999999999
GO:0004190	aspartic-type endopeptidase activity	4/2251	36/18639	0.111111111111111	0.920035539760107	0.647010451089656	0.999999999999999
GO:0016409	palmitoyltransferase activity	4/2251	36/18639	0.111111111111111	0.920035539760107	0.647010451089656	0.999999999999999
GO:0140303	intramembrane lipid transporter activity	5/2251	45/18639	0.111111111111111	0.920035539760107	0.647193143185744	0.999999999999999
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2251	27/18639	0.111111111111111	0.920035539760107	0.649382669739208	0.999999999999999
GO:0005044	scavenger receptor activity	3/2251	27/18639	0.111111111111111	0.920035539760107	0.649382669739208	0.999999999999999
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/2251	27/18639	0.111111111111111	0.920035539760107	0.649382669739208	0.999999999999999
GO:0003730	mRNA 3'-UTR binding	30/2251	262/18639	0.114503816793893	0.948128227997057	0.651347534400954	0.999999999999999
GO:0000400	four-way junction DNA binding	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0015172	acidic amino acid transmembrane transporter activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0016854	racemase and epimerase activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0017075	syntaxin-1 binding	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0017128	phospholipid scramblase activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0031690	adrenergic receptor binding	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0032393	MHC class I receptor activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0034185	apolipoprotein binding	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0035615	clathrin adaptor activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:1901611	phosphatidylglycerol binding	2/2251	18/18639	0.111111111111111	0.920035539760107	0.657765853296222	0.999999999999999
GO:0004180	carboxypeptidase activity	5/2251	46/18639	0.108695652173913	0.900034767156626	0.666764892571583	0.999999999999999
GO:0070001	aspartic-type peptidase activity	4/2251	37/18639	0.108108108108108	0.895169714361185	0.668751900239673	0.999999999999999
GO:0004521	RNA endonuclease activity	8/2251	73/18639	0.10958904109589	0.90743231318805	0.668913763849747	0.999999999999999
GO:0022853	active monoatomic ion transmembrane transporter activity	13/2251	118/18639	0.110169491525424	0.912238628406207	0.680311248215129	0.999999999999999
GO:0160215	deacylase activity	7/2251	65/18639	0.107692307692308	0.891726753921334	0.683538163065905	0.999999999999999
GO:0003756	protein disulfide isomerase activity	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0008381	mechanosensitive monoatomic ion channel activity	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0015245	fatty acid transmembrane transporter activity	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0030506	ankyrin binding	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0031420	alkali metal ion binding	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0034987	immunoglobulin receptor binding	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0042577	lipid phosphatase activity	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0042834	peptidoglycan binding	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0046624	sphingolipid transporter activity	2/2251	19/18639	0.105263157894737	0.871612616614838	0.687218379958451	0.999999999999999
GO:0016741	transferase activity, transferring one-carbon groups	24/2251	215/18639	0.111627906976744	0.924314774828758	0.691294580061968	0.999999999999999
GO:0003785	actin monomer binding	3/2251	29/18639	0.103448275862069	0.856584812880099	0.69761730393152	0.999999999999999
GO:0005416	amino acid:monoatomic cation symporter activity	3/2251	29/18639	0.103448275862069	0.856584812880099	0.69761730393152	0.999999999999999
GO:0016417	S-acyltransferase activity	3/2251	29/18639	0.103448275862069	0.856584812880099	0.69761730393152	0.999999999999999
GO:0043236	laminin binding	3/2251	29/18639	0.103448275862069	0.856584812880099	0.69761730393152	0.999999999999999
GO:0099604	ligand-gated calcium channel activity	3/2251	29/18639	0.103448275862069	0.856584812880099	0.69761730393152	0.999999999999999
GO:1902936	phosphatidylinositol bisphosphate binding	12/2251	111/18639	0.108108108108108	0.895169714361185	0.702129064969052	0.999999999999999
GO:0000339	RNA cap binding	2/2251	20/18639	0.1	0.828031985784096	0.714552127916917	0.999999999999999
GO:0010851	cyclase regulator activity	2/2251	20/18639	0.1	0.828031985784096	0.714552127916917	0.999999999999999
GO:0015095	magnesium ion transmembrane transporter activity	2/2251	20/18639	0.1	0.828031985784096	0.714552127916917	0.999999999999999
GO:0030742	GTP-dependent protein binding	2/2251	20/18639	0.1	0.828031985784096	0.714552127916917	0.999999999999999
GO:0140939	histone H4 methyltransferase activity	2/2251	20/18639	0.1	0.828031985784096	0.714552127916917	0.999999999999999
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2251	30/18639	0.1	0.828031985784096	0.719770186533037	0.999999999999999
GO:0031210	phosphatidylcholine binding	3/2251	30/18639	0.1	0.828031985784096	0.719770186533037	0.999999999999999
GO:0070566	adenylyltransferase activity	3/2251	30/18639	0.1	0.828031985784096	0.719770186533037	0.999999999999999
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0003796	lysozyme activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0004090	carbonyl reductase (NADPH) activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0005345	purine nucleobase transmembrane transporter activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0005381	iron ion transmembrane transporter activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0015187	glycine transmembrane transporter activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0015203	polyamine transmembrane transporter activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0015643	toxic substance binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0031434	mitogen-activated protein kinase kinase binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0031720	haptoglobin binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0032052	bile acid binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0043121	neurotrophin binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0050815	phosphoserine residue binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0070097	delta-catenin binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0070739	protein-glutamic acid ligase activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0070740	tubulin-glutamic acid ligase activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:0140940	histone H2A methyltransferase activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:1990259	histone H2AQ104 methyltransferase activity	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:1990763	arrestin family protein binding	1/2251	10/18639	0.1	0.828031985784096	0.724012509936546	0.999999999999999
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	13/2251	122/18639	0.10655737704918	0.882329165179774	0.725977472128985	0.999999999999999
GO:0070888	E-box binding	6/2251	59/18639	0.101694915254237	0.842066426221115	0.732276302862248	0.999999999999999
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2251	21/18639	0.0952380952380952	0.788601891222949	0.739849063083886	0.999999999999999
GO:0036122	BMP binding	2/2251	21/18639	0.0952380952380952	0.788601891222949	0.739849063083886	0.999999999999999
GO:0061891	calcium ion sensor activity	2/2251	21/18639	0.0952380952380952	0.788601891222949	0.739849063083886	0.999999999999999
GO:0140312	cargo adaptor activity	2/2251	21/18639	0.0952380952380952	0.788601891222949	0.739849063083886	0.999999999999999
GO:0016411	acylglycerol O-acyltransferase activity	3/2251	31/18639	0.0967741935483871	0.801321276565254	0.740638160108233	0.999999999999999
GO:0047499	calcium-independent phospholipase A2 activity	3/2251	31/18639	0.0967741935483871	0.801321276565254	0.740638160108233	0.999999999999999
GO:0070325	lipoprotein particle receptor binding	3/2251	31/18639	0.0967741935483871	0.801321276565254	0.740638160108233	0.999999999999999
GO:0008137	NADH dehydrogenase (ubiquinone) activity	4/2251	41/18639	0.0975609756097561	0.807836083691801	0.746298963390851	0.999999999999999
GO:0033293	monocarboxylic acid binding	8/2251	79/18639	0.10126582278481	0.838513403325667	0.75287031973645	0.999999999999999
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0001851	complement component C3b binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0002162	dystroglycan binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0004016	adenylate cyclase activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0005225	volume-sensitive anion channel activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0008503	benzodiazepine receptor activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0015205	nucleobase transmembrane transporter activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0019206	nucleoside kinase activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0031731	CCR6 chemokine receptor binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0032050	clathrin heavy chain binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0034056	estrogen response element binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0034511	U3 snoRNA binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0047676	arachidonate-CoA ligase activity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0070697	activin receptor binding	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0097493	structural molecule activity conferring elasticity	1/2251	11/18639	0.0909090909090909	0.752756350712815	0.757360936590303	0.999999999999999
GO:0042626	ATPase-coupled transmembrane transporter activity	10/2251	98/18639	0.102040816326531	0.844930597738873	0.760214935283759	0.999999999999999
GO:0022884	macromolecule transmembrane transporter activity	3/2251	32/18639	0.09375	0.77627998667259	0.76025041712486	0.999999999999999
GO:0016881	acid-amino acid ligase activity	2/2251	22/18639	0.0909090909090909	0.752756350712815	0.763202259363589	0.999999999999999
GO:0031683	G-protein beta/gamma-subunit complex binding	2/2251	22/18639	0.0909090909090909	0.752756350712815	0.763202259363589	0.999999999999999
GO:0033691	sialic acid binding	2/2251	22/18639	0.0909090909090909	0.752756350712815	0.763202259363589	0.999999999999999
GO:0140784	metal ion sensor activity	2/2251	22/18639	0.0909090909090909	0.752756350712815	0.763202259363589	0.999999999999999
GO:0004520	DNA endonuclease activity	4/2251	42/18639	0.0952380952380952	0.788601891222949	0.763350752068432	0.999999999999999
GO:0019894	kinesin binding	4/2251	42/18639	0.0952380952380952	0.788601891222949	0.763350752068432	0.999999999999999
GO:0015179	L-amino acid transmembrane transporter activity	6/2251	62/18639	0.0967741935483871	0.801321276565254	0.775158064864162	0.999999999999999
GO:0008194	UDP-glycosyltransferase activity	15/2251	145/18639	0.103448275862069	0.856584812880099	0.775615166746412	0.999999999999999
GO:0015101	organic cation transmembrane transporter activity	8/2251	81/18639	0.0987654320987654	0.81780936867565	0.777236354124804	0.999999999999999
GO:0004602	glutathione peroxidase activity	2/2251	23/18639	0.0869565217391304	0.720027813725301	0.784712022758377	0.999999999999999
GO:0008171	O-methyltransferase activity	2/2251	23/18639	0.0869565217391304	0.720027813725301	0.784712022758377	0.999999999999999
GO:0031681	G-protein beta-subunit binding	2/2251	23/18639	0.0869565217391304	0.720027813725301	0.784712022758377	0.999999999999999
GO:0042171	lysophosphatidic acid acyltransferase activity	2/2251	23/18639	0.0869565217391304	0.720027813725301	0.784712022758377	0.999999999999999
GO:0071617	lysophospholipid acyltransferase activity	2/2251	23/18639	0.0869565217391304	0.720027813725301	0.784712022758377	0.999999999999999
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0003995	acyl-CoA dehydrogenase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0004000	adenosine deaminase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0004300	enoyl-CoA hydratase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0004859	phospholipase inhibitor activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0004875	complement receptor activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0005025	transforming growth factor beta receptor activity, type I	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0005026	transforming growth factor beta receptor activity, type II	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0005049	nuclear export signal receptor activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0005247	voltage-gated chloride channel activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0005436	sodium:phosphate symporter activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0010853	cyclase activator activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0015132	prostaglandin transmembrane transporter activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0015166	polyol transmembrane transporter activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0015368	calcium:monoatomic cation antiporter activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0016361	activin receptor activity, type I	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0016362	activin receptor activity, type II	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0016801	hydrolase activity, acting on ether bonds	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0016803	ether hydrolase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0016840	carbon-nitrogen lyase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0017002	activin receptor activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0036009	protein-glutamine N-methyltransferase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0042301	phosphate ion binding	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:1990817	poly(A) RNA polymerase activity	1/2251	12/18639	0.0833333333333333	0.69002665482008	0.786681343060951	0.999999999999999
GO:0003954	NADH dehydrogenase activity	4/2251	44/18639	0.0909090909090909	0.752756350712815	0.794753855555734	0.999999999999999
GO:0015035	protein-disulfide reductase activity	3/2251	34/18639	0.0882352941176471	0.730616458044791	0.795856123610821	0.999999999999999
GO:0016831	carboxy-lyase activity	3/2251	34/18639	0.0882352941176471	0.730616458044791	0.795856123610821	0.999999999999999
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/2251	54/18639	0.0925925925925926	0.766696283133422	0.796943254766449	0.999999999999999
GO:0004806	triacylglycerol lipase activity	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0005315	phosphate transmembrane transporter activity	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0030215	semaphorin receptor binding	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0050431	transforming growth factor beta binding	2/2251	24/18639	0.0833333333333333	0.69002665482008	0.804482788966568	0.999999999999999
GO:0051539	4 iron, 4 sulfur cluster binding	4/2251	45/18639	0.0888888888888889	0.736028431808085	0.809150022616221	0.999999999999999
GO:0004623	phospholipase A2 activity	3/2251	35/18639	0.0857142857142857	0.709741702100654	0.811935494235988	0.999999999999999
GO:0005343	organic acid:sodium symporter activity	3/2251	35/18639	0.0857142857142857	0.709741702100654	0.811935494235988	0.999999999999999
GO:0008253	5'-nucleotidase activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0008417	fucosyltransferase activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0017154	semaphorin receptor activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0030955	potassium ion binding	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0031432	titin binding	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0035673	oligopeptide transmembrane transporter activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0071714	icosanoid transmembrane transporter activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2251	13/18639	0.0769230769230769	0.636947681372382	0.812460067319812	0.999999999999999
GO:0003707	nuclear steroid receptor activity	2/2251	25/18639	0.08	0.662425588627277	0.822620664299267	0.999999999999999
GO:0008483	transaminase activity	2/2251	25/18639	0.08	0.662425588627277	0.822620664299267	0.999999999999999
GO:0017022	myosin binding	7/2251	76/18639	0.0921052631578947	0.762661039537983	0.82685043631656	0.999999999999999
GO:0098631	cell adhesion mediator activity	7/2251	76/18639	0.0921052631578947	0.762661039537983	0.82685043631656	0.999999999999999
GO:0045505	dynein intermediate chain binding	3/2251	36/18639	0.0833333333333333	0.69002665482008	0.826928679976564	0.999999999999999
GO:0055106	ubiquitin-protein transferase regulator activity	3/2251	36/18639	0.0833333333333333	0.69002665482008	0.826928679976564	0.999999999999999
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/2251	67/18639	0.0895522388059701	0.74152118129919	0.834814716042721	0.999999999999999
GO:0004705	JUN kinase activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0008559	ABC-type xenobiotic transporter activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0016530	metallochaperone activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0032036	myosin heavy chain binding	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0061783	peptidoglycan muralytic activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0098821	BMP receptor activity	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:1901612	cardiolipin binding	1/2251	14/18639	0.0714285714285714	0.591451418417211	0.835124750475782	0.999999999999999
GO:0005504	fatty acid binding	4/2251	47/18639	0.0851063829787234	0.704708073007741	0.835463933432418	0.999999999999999
GO:0004435	phosphatidylinositol phospholipase C activity	2/2251	26/18639	0.0769230769230769	0.636947681372382	0.839231499883348	0.999999999999999
GO:0051139	metal cation:proton antiporter activity	2/2251	26/18639	0.0769230769230769	0.636947681372382	0.839231499883348	0.999999999999999
GO:0120014	phospholipid transfer activity	2/2251	26/18639	0.0769230769230769	0.636947681372382	0.839231499883348	0.999999999999999
GO:0032266	phosphatidylinositol-3-phosphate binding	4/2251	48/18639	0.0833333333333333	0.69002665482008	0.84744045591826	0.999999999999999
GO:0005501	retinoid binding	3/2251	38/18639	0.0789473684210526	0.653709462461128	0.853856742611267	0.999999999999999
GO:0019840	isoprenoid binding	3/2251	38/18639	0.0789473684210526	0.653709462461128	0.853856742611267	0.999999999999999
GO:0042887	amide transmembrane transporter activity	3/2251	38/18639	0.0789473684210526	0.653709462461128	0.853856742611267	0.999999999999999
GO:0004519	endonuclease activity	12/2251	127/18639	0.094488188976378	0.782392427512532	0.854108668098597	0.999999999999999
GO:0004364	glutathione transferase activity	2/2251	27/18639	0.0740740740740741	0.613357026506738	0.85441940629488	0.999999999999999
GO:0005385	zinc ion transmembrane transporter activity	2/2251	27/18639	0.0740740740740741	0.613357026506738	0.85441940629488	0.999999999999999
GO:0008320	protein transmembrane transporter activity	2/2251	27/18639	0.0740740740740741	0.613357026506738	0.85441940629488	0.999999999999999
GO:0016405	CoA-ligase activity	2/2251	27/18639	0.0740740740740741	0.613357026506738	0.85441940629488	0.999999999999999
GO:0004089	carbonate dehydratase activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0004467	long-chain fatty acid-CoA ligase activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0005523	tropomyosin binding	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0008252	nucleotidase activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0015116	sulfate transmembrane transporter activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0015250	water channel activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0016846	carbon-sulfur lyase activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0017081	chloride channel regulator activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0031005	filamin binding	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0033130	acetylcholine receptor binding	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0045504	dynein heavy chain binding	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0048531	beta-1,3-galactosyltransferase activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0140161	monocarboxylate:sodium symporter activity	1/2251	15/18639	0.0666666666666667	0.552021323856064	0.855051418216937	0.999999999999999
GO:0015459	potassium channel regulator activity	5/2251	59/18639	0.0847457627118644	0.701722021850929	0.855553727463859	0.999999999999999
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/2251	59/18639	0.0847457627118644	0.701722021850929	0.855553727463859	0.999999999999999
GO:0004620	phospholipase activity	10/2251	109/18639	0.0917431192660551	0.759662372278987	0.861984517578885	0.999999999999999
GO:0008236	serine-type peptidase activity	19/2251	194/18639	0.0979381443298969	0.810959161334939	0.864061556937847	0.999999999999999
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/2251	39/18639	0.0769230769230769	0.636947681372382	0.86589393883642	0.999999999999999
GO:0050698	proteoglycan sulfotransferase activity	2/2251	28/18639	0.0714285714285714	0.591451418417211	0.868285630402818	0.999999999999999
GO:0000062	fatty-acyl-CoA binding	1/2251	16/18639	0.0625	0.51751999111506	0.872570708250962	0.999999999999999
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/2251	16/18639	0.0625	0.51751999111506	0.872570708250962	0.999999999999999
GO:0015378	sodium:chloride symporter activity	1/2251	16/18639	0.0625	0.51751999111506	0.872570708250962	0.999999999999999
GO:0015562	efflux transmembrane transporter activity	1/2251	16/18639	0.0625	0.51751999111506	0.872570708250962	0.999999999999999
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/2251	16/18639	0.0625	0.51751999111506	0.872570708250962	0.999999999999999
GO:0055102	lipase inhibitor activity	1/2251	16/18639	0.0625	0.51751999111506	0.872570708250962	0.999999999999999
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	12/2251	130/18639	0.0923076923076923	0.764337217646858	0.87437524791893	0.999999999999999
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	5/2251	61/18639	0.0819672131147541	0.67871474244598	0.874685956324584	0.999999999999999
GO:0050997	quaternary ammonium group binding	3/2251	40/18639	0.075	0.621023989338072	0.877048337375035	0.999999999999999
GO:0004181	metallocarboxypeptidase activity	2/2251	29/18639	0.0689655172413793	0.571056541920066	0.880927728659952	0.999999999999999
GO:0035250	UDP-galactosyltransferase activity	2/2251	29/18639	0.0689655172413793	0.571056541920066	0.880927728659952	0.999999999999999
GO:0017171	serine hydrolase activity	19/2251	198/18639	0.095959595959596	0.794576147974637	0.884996754846203	0.999999999999999
GO:0030165	PDZ domain binding	7/2251	83/18639	0.0843373493975904	0.698340228974539	0.887598142239378	0.999999999999999
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0008484	sulfuric ester hydrolase activity	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0008569	minus-end-directed microtubule motor activity	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0038191	neuropilin binding	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0070402	NADPH binding	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0070492	oligosaccharide binding	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:1901567	fatty acid derivative binding	1/2251	17/18639	0.0588235294117647	0.487077638696527	0.887973346694128	0.999999999999999
GO:0005507	copper ion binding	5/2251	63/18639	0.0793650793650794	0.65716824268579	0.891620760146585	0.999999999999999
GO:0016769	transferase activity, transferring nitrogenous groups	2/2251	30/18639	0.0666666666666667	0.552021323856064	0.892438981669017	0.999999999999999
GO:0048019	receptor antagonist activity	2/2251	30/18639	0.0666666666666667	0.552021323856064	0.892438981669017	0.999999999999999
GO:0005544	calcium-dependent phospholipid binding	4/2251	53/18639	0.0754716981132075	0.624929800591771	0.896783896772859	0.999999999999999
GO:0005372	water transmembrane transporter activity	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0008308	voltage-gated monoatomic anion channel activity	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0015373	monoatomic anion:sodium symporter activity	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0070628	proteasome binding	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0098641	cadherin binding involved in cell-cell adhesion	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0099602	neurotransmitter receptor regulator activity	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:1990381	ubiquitin-specific protease binding	1/2251	18/18639	0.0555555555555556	0.460017769880053	0.901514963952828	0.999999999999999
GO:0016878	acid-thiol ligase activity	2/2251	31/18639	0.0645161290322581	0.534214184376836	0.902908003845623	0.999999999999999
GO:0050661	NADP binding	4/2251	54/18639	0.0740740740740741	0.613357026506738	0.904771148133372	0.999999999999999
GO:0009055	electron transfer activity	10/2251	116/18639	0.0862068965517241	0.713820677400083	0.906434548073975	0.999999999999999
GO:0008374	O-acyltransferase activity	4/2251	55/18639	0.0727272727272727	0.602205080570252	0.912205742221283	0.999999999999999
GO:0098632	cell-cell adhesion mediator activity	4/2251	55/18639	0.0727272727272727	0.602205080570252	0.912205742221283	0.999999999999999
GO:0015399	primary active transmembrane transporter activity	15/2251	166/18639	0.0903614457831325	0.748221673901291	0.912298725754283	0.999999999999999
GO:0008378	galactosyltransferase activity	2/2251	32/18639	0.0625	0.51751999111506	0.912418509627007	0.999999999999999
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/2251	32/18639	0.0625	0.51751999111506	0.912418509627007	0.999999999999999
GO:0042910	xenobiotic transmembrane transporter activity	2/2251	32/18639	0.0625	0.51751999111506	0.912418509627007	0.999999999999999
GO:0047498	calcium-dependent phospholipase A2 activity	2/2251	32/18639	0.0625	0.51751999111506	0.912418509627007	0.999999999999999
GO:0005539	glycosaminoglycan binding	23/2251	242/18639	0.0950413223140496	0.786972548472488	0.91279873392217	0.999999999999999
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2251	19/18639	0.0526315789473684	0.435806308307419	0.913420329730294	0.999999999999999
GO:0050145	nucleoside monophosphate kinase activity	1/2251	19/18639	0.0526315789473684	0.435806308307419	0.913420329730294	0.999999999999999
GO:0120227	acyl-CoA binding	1/2251	19/18639	0.0526315789473684	0.435806308307419	0.913420329730294	0.999999999999999
GO:0016790	thiolester hydrolase activity	3/2251	44/18639	0.0681818181818182	0.564567263034611	0.913836029261141	0.999999999999999
GO:0019205	nucleobase-containing compound kinase activity	3/2251	44/18639	0.0681818181818182	0.564567263034611	0.913836029261141	0.999999999999999
GO:0030547	signaling receptor inhibitor activity	3/2251	44/18639	0.0681818181818182	0.564567263034611	0.913836029261141	0.999999999999999
GO:0008173	RNA methyltransferase activity	5/2251	67/18639	0.0746268656716418	0.617934317749325	0.919638043827752	0.999999999999999
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/2251	33/18639	0.0606060606060606	0.501837567141876	0.921049204135491	0.999999999999999
GO:0042923	neuropeptide binding	2/2251	33/18639	0.0606060606060606	0.501837567141876	0.921049204135491	0.999999999999999
GO:0016758	hexosyltransferase activity	18/2251	197/18639	0.0913705583756345	0.756577448939783	0.921138082633205	0.999999999999999
GO:0046915	transition metal ion transmembrane transporter activity	3/2251	45/18639	0.0666666666666667	0.552021323856064	0.921313601164349	0.999999999999999
GO:0016408	C-acyltransferase activity	1/2251	20/18639	0.05	0.414015992892048	0.923887077194156	0.999999999999999
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/2251	20/18639	0.05	0.414015992892048	0.923887077194156	0.999999999999999
GO:0052745	inositol phosphate phosphatase activity	1/2251	20/18639	0.05	0.414015992892048	0.923887077194156	0.999999999999999
GO:0004601	peroxidase activity	4/2251	57/18639	0.0701754385964912	0.581075077743225	0.92553931315002	0.999999999999999
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	5/2251	68/18639	0.0735294117647059	0.608847048370659	0.925555920070101	0.999999999999999
GO:0016298	lipase activity	11/2251	130/18639	0.0846153846153846	0.70064244950962	0.925873463116477	0.999999999999999
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/2251	34/18639	0.0588235294117647	0.487077638696527	0.928873771668283	0.999999999999999
GO:0090482	vitamin transmembrane transporter activity	2/2251	34/18639	0.0588235294117647	0.487077638696527	0.928873771668283	0.999999999999999
GO:0033218	amide binding	23/2251	247/18639	0.0931174089068826	0.771041930082357	0.929420973910263	0.999999999999999
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/2251	58/18639	0.0689655172413793	0.571056541920066	0.93149730019144	0.999999999999999
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	16/2251	181/18639	0.0883977900552486	0.731961976383731	0.932728352631669	0.999999999999999
GO:0001846	opsonin binding	1/2251	21/18639	0.0476190476190476	0.394300945611474	0.933088977899669	0.999999999999999
GO:0009975	cyclase activity	1/2251	21/18639	0.0476190476190476	0.394300945611474	0.933088977899669	0.999999999999999
GO:0010314	phosphatidylinositol-5-phosphate binding	1/2251	21/18639	0.0476190476190476	0.394300945611474	0.933088977899669	0.999999999999999
GO:0015125	bile acid transmembrane transporter activity	1/2251	21/18639	0.0476190476190476	0.394300945611474	0.933088977899669	0.999999999999999
GO:0019200	carbohydrate kinase activity	1/2251	21/18639	0.0476190476190476	0.394300945611474	0.933088977899669	0.999999999999999
GO:0051428	peptide hormone receptor binding	1/2251	21/18639	0.0476190476190476	0.394300945611474	0.933088977899669	0.999999999999999
GO:0072341	modified amino acid binding	7/2251	91/18639	0.0769230769230769	0.636947681372382	0.93404689966374	0.999999999999999
GO:0140359	ABC-type transporter activity	3/2251	47/18639	0.0638297872340425	0.528531054755806	0.934515315130276	0.999999999999999
GO:0008201	heparin binding	15/2251	172/18639	0.0872093023255814	0.722120917834967	0.935278560548832	0.999999999999999
GO:0016229	steroid dehydrogenase activity	2/2251	35/18639	0.0571428571428571	0.473161134733769	0.935960939997513	0.999999999999999
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/2251	48/18639	0.0625	0.51751999111506	0.940320305744411	0.999999999999999
GO:0015377	chloride:monoatomic cation symporter activity	1/2251	22/18639	0.0454545454545455	0.376378175356407	0.941178821639483	0.999999999999999
GO:0030246	carbohydrate binding	26/2251	280/18639	0.0928571428571429	0.768886843942375	0.94209105609521	0.999999999999999
GO:0004033	aldo-keto reductase (NADPH) activity	2/2251	36/18639	0.0555555555555556	0.460017769880053	0.942374602351686	0.999999999999999
GO:0004252	serine-type endopeptidase activity	15/2251	176/18639	0.0852272727272727	0.705709078793264	0.947568584201321	0.999999999999999
GO:0022829	wide pore channel activity	2/2251	37/18639	0.0540540540540541	0.447584857180592	0.948173982219827	0.999999999999999
GO:0030280	structural constituent of skin epidermis	2/2251	37/18639	0.0540540540540541	0.447584857180592	0.948173982219827	0.999999999999999
GO:0042805	actinin binding	2/2251	37/18639	0.0540540540540541	0.447584857180592	0.948173982219827	0.999999999999999
GO:0005212	structural constituent of eye lens	1/2251	23/18639	0.0434782608695652	0.36001390686265	0.948290948861351	0.999999999999999
GO:0015085	calcium ion transmembrane transporter activity	12/2251	147/18639	0.0816326530612245	0.675944478191099	0.950455863904746	0.999999999999999
GO:0005109	frizzled binding	2/2251	38/18639	0.0526315789473684	0.435806308307419	0.953413828864747	0.999999999999999
GO:0048029	monosaccharide binding	5/2251	74/18639	0.0675675675675676	0.559481071475741	0.953575540848253	0.999999999999999
GO:0004622	lysophospholipase activity	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0005540	hyaluronic acid binding	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0015149	hexose transmembrane transporter activity	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0015295	solute:proton symporter activity	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0055056	D-glucose transmembrane transporter activity	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0140612	DNA damage sensor activity	1/2251	24/18639	0.0416666666666667	0.34501332741004	0.954543477552428	0.999999999999999
GO:0016597	amino acid binding	3/2251	51/18639	0.0588235294117647	0.487077638696527	0.954994224649173	0.999999999999999
GO:0016830	carbon-carbon lyase activity	3/2251	51/18639	0.0588235294117647	0.487077638696527	0.954994224649173	0.999999999999999
GO:0016209	antioxidant activity	6/2251	86/18639	0.0697674418604651	0.577696734267974	0.956601147871501	0.999999999999999
GO:0001848	complement binding	1/2251	25/18639	0.04	0.331212794313638	0.960040261437977	0.999999999999999
GO:0005537	D-mannose binding	1/2251	25/18639	0.04	0.331212794313638	0.960040261437977	0.999999999999999
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2251	25/18639	0.04	0.331212794313638	0.960040261437977	0.999999999999999
GO:0015645	fatty acid ligase activity	1/2251	25/18639	0.04	0.331212794313638	0.960040261437977	0.999999999999999
GO:0047617	fatty acyl-CoA hydrolase activity	1/2251	25/18639	0.04	0.331212794313638	0.960040261437977	0.999999999999999
GO:0120515	fatty acid-CoA ligase activity	1/2251	25/18639	0.04	0.331212794313638	0.960040261437977	0.999999999999999
GO:0016798	hydrolase activity, acting on glycosyl bonds	10/2251	130/18639	0.0769230769230769	0.636947681372382	0.960144135039495	0.999999999999999
GO:0015144	carbohydrate transmembrane transporter activity	2/2251	40/18639	0.05	0.414015992892048	0.962412859855148	0.999999999999999
GO:0071855	neuropeptide receptor binding	2/2251	40/18639	0.05	0.414015992892048	0.962412859855148	0.999999999999999
GO:0019843	rRNA binding	4/2251	65/18639	0.0615384615384615	0.509558145097905	0.962459498210676	0.999999999999999
GO:0016860	intramolecular oxidoreductase activity	3/2251	53/18639	0.0566037735849057	0.468697350443828	0.962820842407419	0.999999999999999
GO:0015145	monosaccharide transmembrane transporter activity	1/2251	26/18639	0.0384615384615385	0.318473840686191	0.964872611900162	0.999999999999999
GO:0016289	acyl-CoA hydrolase activity	1/2251	26/18639	0.0384615384615385	0.318473840686191	0.964872611900162	0.999999999999999
GO:0097602	cullin family protein binding	1/2251	26/18639	0.0384615384615385	0.318473840686191	0.964872611900162	0.999999999999999
GO:0005179	hormone activity	10/2251	132/18639	0.0757575757575758	0.627296958927345	0.964982850297185	0.999999999999999
GO:0008237	metallopeptidase activity	15/2251	184/18639	0.0815217391304348	0.67502607536747	0.966214913302302	0.999999999999999
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/2251	41/18639	0.0487804878048781	0.4039180418459	0.966261177982398	0.999999999999999
GO:0140828	metal cation:monoatomic cation antiporter activity	2/2251	41/18639	0.0487804878048781	0.4039180418459	0.966261177982398	0.999999999999999
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/2251	122/18639	0.0737704918032787	0.610843268201382	0.966303446255342	0.999999999999999
GO:0008395	steroid hydroxylase activity	1/2251	27/18639	0.037037037037037	0.306678513253369	0.96912081211575	0.999999999999999
GO:0015252	proton channel activity	1/2251	27/18639	0.037037037037037	0.306678513253369	0.96912081211575	0.999999999999999
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/2251	27/18639	0.037037037037037	0.306678513253369	0.96912081211575	0.999999999999999
GO:0015370	solute:sodium symporter activity	5/2251	79/18639	0.0632911392405063	0.524070877078542	0.969172399938207	0.999999999999999
GO:0015171	amino acid transmembrane transporter activity	7/2251	102/18639	0.0686274509803922	0.568257245145948	0.970128935836968	0.999999999999999
GO:0000049	tRNA binding	5/2251	80/18639	0.0625	0.51751999111506	0.971641178732302	0.999999999999999
GO:0170055	lipid transmembrane transporter activity	3/2251	56/18639	0.0535714285714286	0.443588563812909	0.972196076440575	0.999999999999999
GO:0045499	chemorepellent activity	1/2251	28/18639	0.0357142857142857	0.295725709208606	0.972855448475488	0.999999999999999
GO:0051119	sugar transmembrane transporter activity	1/2251	28/18639	0.0357142857142857	0.295725709208606	0.972855448475488	0.999999999999999
GO:0051393	alpha-actinin binding	1/2251	28/18639	0.0357142857142857	0.295725709208606	0.972855448475488	0.999999999999999
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/2251	28/18639	0.0357142857142857	0.295725709208606	0.972855448475488	0.999999999999999
GO:0005201	extracellular matrix structural constituent	13/2251	168/18639	0.0773809523809524	0.640739036618646	0.973983545069865	0.999999999999999
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/2251	44/18639	0.0454545454545455	0.376378175356407	0.975661484814792	0.999999999999999
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/2251	70/18639	0.0571428571428571	0.473161134733769	0.975979744723057	0.999999999999999
GO:0016853	isomerase activity	14/2251	180/18639	0.0777777777777778	0.644024877832075	0.97647017805615	0.999999999999999
GO:0042562	hormone binding	6/2251	94/18639	0.0638297872340425	0.528531054755806	0.976793490151822	0.999999999999999
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/2251	30/18639	0.0333333333333333	0.276010661928032	0.979024774417664	0.999999999999999
GO:0015215	nucleotide transmembrane transporter activity	1/2251	30/18639	0.0333333333333333	0.276010661928032	0.979024774417664	0.999999999999999
GO:0033612	receptor serine/threonine kinase binding	1/2251	30/18639	0.0333333333333333	0.276010661928032	0.979024774417664	0.999999999999999
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/2251	60/18639	0.05	0.414015992892048	0.981255171589086	0.999999999999999
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/2251	31/18639	0.032258064516129	0.267107092188418	0.981562000103399	0.999999999999999
GO:0005452	solute:inorganic anion antiporter activity	1/2251	31/18639	0.032258064516129	0.267107092188418	0.981562000103399	0.999999999999999
GO:0072349	modified amino acid transmembrane transporter activity	1/2251	31/18639	0.032258064516129	0.267107092188418	0.981562000103399	0.999999999999999
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	9/2251	132/18639	0.0681818181818182	0.564567263034611	0.983274879149606	0.999999999999999
GO:0015106	bicarbonate transmembrane transporter activity	1/2251	32/18639	0.03125	0.25875999555753	0.983792435280057	0.999999999999999
GO:0004222	metalloendopeptidase activity	7/2251	110/18639	0.0636363636363636	0.52692944549897	0.983818092305199	0.999999999999999
GO:0051536	iron-sulfur cluster binding	4/2251	76/18639	0.0526315789473684	0.435806308307419	0.986167215443543	0.999999999999999
GO:0016829	lyase activity	15/2251	200/18639	0.075	0.621023989338072	0.986891726379431	0.999999999999999
GO:0051540	metal cluster binding	4/2251	77/18639	0.051948051948052	0.430146486121608	0.987402241828885	0.999999999999999
GO:0015020	glucuronosyltransferase activity	1/2251	34/18639	0.0294117647058824	0.243538819348264	0.987476779119538	0.999999999999999
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2251	34/18639	0.0294117647058824	0.243538819348264	0.987476779119538	0.999999999999999
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/2251	34/18639	0.0294117647058824	0.243538819348264	0.987476779119538	0.999999999999999
GO:0019825	oxygen binding	1/2251	34/18639	0.0294117647058824	0.243538819348264	0.987476779119538	0.999999999999999
GO:0019199	transmembrane receptor protein kinase activity	4/2251	78/18639	0.0512820512820513	0.424631787581588	0.98853177125963	0.999999999999999
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/2251	52/18639	0.0384615384615385	0.318473840686191	0.989975341709686	0.999999999999999
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2251	36/18639	0.0277777777777778	0.230008884940027	0.990323875101471	0.999999999999999
GO:0008146	sulfotransferase activity	2/2251	53/18639	0.0377358490566038	0.312464900295885	0.991040224035265	0.999999999999999
GO:0017046	peptide hormone binding	2/2251	53/18639	0.0377358490566038	0.312464900295885	0.991040224035265	0.999999999999999
GO:0005262	calcium channel activity	8/2251	131/18639	0.0610687022900763	0.505668388265097	0.99231876870351	0.999999999999999
GO:0004867	serine-type endopeptidase inhibitor activity	5/2251	95/18639	0.0526315789473684	0.435806308307419	0.992327693549083	0.999999999999999
GO:0031406	carboxylic acid binding	13/2251	187/18639	0.0695187165775401	0.575637209368623	0.992353989825557	0.999999999999999
GO:0005506	iron ion binding	10/2251	154/18639	0.0649350649350649	0.53768310765201	0.992421145387153	0.999999999999999
GO:0016782	transferase activity, transferring sulphur-containing groups	3/2251	70/18639	0.0428571428571429	0.354870851050327	0.993205425781512	0.999999999999999
GO:0043177	organic acid binding	13/2251	189/18639	0.0687830687830688	0.569545810327685	0.993324874373313	0.999999999999999
GO:0030170	pyridoxal phosphate binding	2/2251	56/18639	0.0357142857142857	0.295725709208606	0.993613561550708	0.999999999999999
GO:0140299	molecular sensor activity	3/2251	71/18639	0.0422535211267606	0.349872670049618	0.993873380454279	0.999999999999999
GO:0071949	FAD binding	1/2251	40/18639	0.025	0.207007996446024	0.994223912676798	0.999999999999999
GO:0070279	vitamin B6 binding	2/2251	57/18639	0.0350877192982456	0.290537538871613	0.994298123103621	0.999999999999999
GO:0008307	structural constituent of muscle	1/2251	42/18639	0.0238095238095238	0.197150472805737	0.995537475595701	0.999999999999999
GO:0008083	growth factor activity	10/2251	162/18639	0.0617283950617284	0.511130855422281	0.995838554425684	0.999999999999999
GO:0015078	proton transmembrane transporter activity	12/2251	185/18639	0.0648648648648649	0.537101828616711	0.995932825330088	0.999999999999999
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/2251	60/18639	0.0333333333333333	0.276010661928032	0.995948108267015	0.999999999999999
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/2251	43/18639	0.0232558139534884	0.192565578089325	0.99607762413762	0.999999999999999
GO:0016836	hydro-lyase activity	2/2251	61/18639	0.0327868852459016	0.271485896978392	0.996385882747134	0.999999999999999
GO:0015294	solute:monoatomic cation symporter activity	6/2251	116/18639	0.0517241379310345	0.42829240644005	0.996405623968932	0.999999999999999
GO:0046943	carboxylic acid transmembrane transporter activity	12/2251	188/18639	0.0638297872340425	0.528531054755806	0.996728537839366	0.999999999999999
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4/2251	91/18639	0.043956043956044	0.363970103641361	0.996731579378996	0.999999999999999
GO:0005342	organic acid transmembrane transporter activity	12/2251	189/18639	0.0634920634920635	0.525734594148632	0.996959294684522	0.999999999999999
GO:1901682	sulfur compound transmembrane transporter activity	2/2251	63/18639	0.0317460317460317	0.262867297074316	0.997126543681461	0.999999999999999
GO:0099095	ligand-gated monoatomic anion channel activity	1/2251	47/18639	0.0212765957446809	0.176177018251935	0.997659053669697	0.999999999999999
GO:0008188	neuropeptide receptor activity	1/2251	48/18639	0.0208333333333333	0.17250666370502	0.997942480422575	0.999999999999999
GO:0015605	organophosphate ester transmembrane transporter activity	1/2251	50/18639	0.02	0.165606397156819	0.998410577485591	0.999999999999999
GO:0005010	insulin-like growth factor receptor activity	1/2251	51/18639	0.0196078431372549	0.162359212898842	0.998603045616203	0.999999999999999
GO:0050660	flavin adenine dinucleotide binding	3/2251	86/18639	0.0348837209302326	0.288848367133987	0.998747718823837	0.999999999999999
GO:0020037	heme binding	7/2251	142/18639	0.0492957746478873	0.408184781724554	0.998905944699275	0.999999999999999
GO:0005003	ephrin receptor activity	1/2251	53/18639	0.0188679245283019	0.156232450147943	0.998920908439609	0.999999999999999
GO:0005005	transmembrane-ephrin receptor activity	1/2251	53/18639	0.0188679245283019	0.156232450147943	0.998920908439609	0.999999999999999
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/2251	53/18639	0.0188679245283019	0.156232450147943	0.998920908439609	0.999999999999999
GO:0005253	monoatomic anion channel activity	4/2251	103/18639	0.0388349514563107	0.321565819721979	0.999021542493916	0.999999999999999
GO:1901681	sulfur compound binding	18/2251	275/18639	0.0654545454545455	0.541984572513226	0.9991992992139	0.999999999999999
GO:0052689	carboxylic ester hydrolase activity	3/2251	92/18639	0.0326086956521739	0.270010430146988	0.999346861139284	0.999999999999999
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/2251	57/18639	0.0175438596491228	0.145268769435806	0.999356169128163	0.999999999999999
GO:0015297	antiporter activity	6/2251	135/18639	0.0444444444444444	0.368014215904043	0.999370102812578	0.999999999999999
GO:0008509	monoatomic anion transmembrane transporter activity	7/2251	149/18639	0.0469798657718121	0.389008315469038	0.999417816792673	0.999999999999999
GO:0016835	carbon-oxygen lyase activity	2/2251	79/18639	0.0253164556962025	0.209628350831417	0.999553385357501	0.999999999999999
GO:0046906	tetrapyrrole binding	7/2251	152/18639	0.0460526315789474	0.381330519768992	0.999557420714879	0.999999999999999
GO:0016874	ligase activity	8/2251	167/18639	0.0479041916167665	0.39666202911813	0.999632156159224	0.999999999999999
GO:0005254	chloride channel activity	2/2251	83/18639	0.0240963855421687	0.199525779707011	0.999721324964292	0.999999999999999
GO:0015293	symporter activity	6/2251	146/18639	0.0410958904109589	0.340287117445519	0.999779861356444	0.999999999999999
GO:0015108	chloride transmembrane transporter activity	4/2251	121/18639	0.0330578512396694	0.273729582077387	0.999849956379129	0.999999999999999
GO:0004497	monooxygenase activity	3/2251	106/18639	0.0283018867924528	0.234348675221914	0.999860920804137	0.999999999999999
GO:0008514	organic anion transmembrane transporter activity	15/2251	269/18639	0.0557620817843866	0.461727873113808	0.999902322076189	0.999999999999999
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/2251	73/18639	0.0136986301369863	0.113429039148506	0.999918508903837	0.999999999999999
GO:0001653	peptide receptor activity	4/2251	128/18639	0.03125	0.25875999555753	0.999928888322836	0.999999999999999
GO:0030594	neurotransmitter receptor activity	2/2251	97/18639	0.0206185567010309	0.170728244491566	0.999947338411457	0.999999999999999
GO:0015081	sodium ion transmembrane transporter activity	6/2251	164/18639	0.0365853658536585	0.302938531384425	0.999962718981475	0.999999999999999
GO:0015103	inorganic anion transmembrane transporter activity	6/2251	165/18639	0.0363636363636364	0.301102540285126	0.999966281806459	0.999999999999999
GO:0099094	ligand-gated monoatomic cation channel activity	4/2251	136/18639	0.0294117647058824	0.243538819348264	0.999970014216628	0.999999999999999
GO:0008528	G protein-coupled peptide receptor activity	3/2251	122/18639	0.0245901639344262	0.203614422733794	0.999977161281192	0.999999999999999
GO:0005249	voltage-gated potassium channel activity	1/2251	98/18639	0.0102040816326531	0.0844930597738873	0.999996787380251	0.999999999999999
GO:0022804	active transmembrane transporter activity	27/2251	457/18639	0.0590809628008753	0.489209269500451	0.999997368556071	0.999999999999999
GO:0003735	structural constituent of ribosome	5/2251	175/18639	0.0285714285714286	0.236580567366885	0.999997543295617	0.999999999999999
GO:0019842	vitamin binding	3/2251	150/18639	0.02	0.165606397156819	0.999999102172791	0.999999999999999
GO:0015291	secondary active transmembrane transporter activity	12/2251	287/18639	0.0418118466898955	0.346215464439343	0.9999991972797	0.999999999999999
GO:0015276	ligand-gated monoatomic ion channel activity	5/2251	186/18639	0.0268817204301075	0.222589243490348	0.999999254752015	0.999999999999999
GO:0022834	ligand-gated channel activity	5/2251	188/18639	0.0265957446808511	0.220221272814919	0.999999400976865	0.999999999999999
GO:0045182	translation regulator activity	17/2251	356/18639	0.047752808988764	0.395408532537349	0.999999434067248	0.999999999999999
GO:0005244	voltage-gated monoatomic ion channel activity	4/2251	173/18639	0.023121387283237	0.191452482262219	0.999999506854827	0.999999999999999
GO:0022832	voltage-gated channel activity	4/2251	175/18639	0.0228571428571429	0.189264453893508	0.999999606795161	0.999999999999999
GO:0140101	catalytic activity, acting on a tRNA	2/2251	139/18639	0.0143884892086331	0.119141292918575	0.999999679349295	0.999999999999999
GO:0022843	voltage-gated monoatomic cation channel activity	2/2251	143/18639	0.013986013986014	0.115808669340433	0.999999803910129	0.999999999999999
GO:0005267	potassium channel activity	1/2251	124/18639	0.00806451612903226	0.0667767730471045	0.999999889263052	0.999999999999999
GO:0015079	potassium ion transmembrane transporter activity	2/2251	160/18639	0.0125	0.103503998223012	0.999999975960744	0.999999999999999
GO:0046873	metal ion transmembrane transporter activity	21/2251	450/18639	0.0466666666666667	0.386414926699245	0.999999986329647	0.999999999999999
GO:0005261	monoatomic cation channel activity	12/2251	341/18639	0.0351906158357771	0.291389555114638	0.999999995445602	0.999999999999999
GO:0022836	gated channel activity	10/2251	318/18639	0.0314465408805031	0.260387416913238	0.999999997594194	0.999999999999999
GO:0030371	translation repressor activity	10/2251	329/18639	0.0303951367781155	0.251681454645622	0.999999999226653	0.999999999999999
GO:0005216	monoatomic ion channel activity	18/2251	448/18639	0.0401785714285714	0.332691422859681	0.999999999525242	0.999999999999999
GO:1903231	mRNA base-pairing translational repressor activity	2/2251	298/18639	0.00671140939597315	0.0555726164955769	0.999999999999999	0.999999999999999