ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	263/6463	495/18639	0.531313131313131	1.53228306584333	1.23799986541738e-17	1.70596381454515e-14
GO:0060589	nucleoside-triphosphatase regulator activity	255/6463	490/18639	0.520408163265306	1.50083363068266	1.08200250563551e-15	7.45499726382867e-13
GO:0030695	GTPase regulator activity	254/6463	489/18639	0.519427402862986	1.49800516199338	1.65195889851049e-15	7.58799787382484e-13
GO:0140297	DNA-binding transcription factor binding	251/6463	488/18639	0.514344262295082	1.48334561425314	1.07682218602577e-14	3.70965243085879e-12
GO:0019787	ubiquitin-like protein transferase activity	244/6463	479/18639	0.509394572025052	1.46907093114265	1.01934757411547e-13	2.80932191426223e-11
GO:0016755	aminoacyltransferase activity	248/6463	496/18639	0.5	1.44197740987158	8.77152177285589e-13	2.0145261671659e-10
GO:0005096	GTPase activator activity	150/6463	271/18639	0.553505535055351	1.59628495557739	1.95521033038452e-12	3.84897119324268e-10
GO:0004842	ubiquitin-protein transferase activity	225/6463	449/18639	0.501113585746102	1.44518894085125	7.64406511611873e-12	1.31669021625145e-09
GO:0031267	small GTPase binding	152/6463	283/18639	0.537102473498233	1.5489792671412	3.12033731128681e-11	4.77758312772581e-09
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	180/6463	349/18639	0.515759312320917	1.48742655459532	4.72945997773934e-11	6.51719584932481e-09
GO:0046332	SMAD binding	56/6463	79/18639	0.708860759493671	2.04432240386856	5.44421503034717e-11	6.82011664710763e-09
GO:0004674	protein serine/threonine kinase activity	214/6463	433/18639	0.494226327944573	1.42532640051971	1.25450919143777e-10	1.44059472150104e-08
GO:0061659	ubiquitin-like protein ligase activity	188/6463	372/18639	0.505376344086022	1.45748254331106	1.63774179608244e-10	1.73600630384739e-08
GO:0051020	GTPase binding	163/6463	315/18639	0.517460317460318	1.4923321765655	2.78712187848352e-10	2.7433242489645e-08
GO:0001217	DNA-binding transcription repressor activity	143/6463	278/18639	0.514388489208633	1.48347316267364	5.66116264196803e-09	5.20072141375463e-07
GO:0003713	transcription coactivator activity	133/6463	256/18639	0.51953125	1.49830465244469	8.60883833141257e-09	7.41436201292908e-07
GO:0061630	ubiquitin protein ligase activity	173/6463	353/18639	0.490084985835694	1.41338295698461	1.59077843524552e-08	1.2894662845696e-06
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	137/6463	268/18639	0.511194029850746	1.47426048621198	1.94052325821176e-08	1.48557836100878e-06
GO:0106310	protein serine kinase activity	175/6463	361/18639	0.484764542936288	1.39803904004169	3.53151093959613e-08	2.5612747761913e-06
GO:0001221	transcription coregulator binding	68/6463	115/18639	0.591304347826087	1.70529502384813	6.8899304613422e-08	4.74716208786478e-06
GO:0003714	transcription corepressor activity	107/6463	204/18639	0.524509803921569	1.51266257702214	1.26180472144698e-07	8.27984241025683e-06
GO:0140996	histone H3 kinase activity	170/6463	357/18639	0.476190476190476	1.37331181892531	2.48390200838039e-07	1.5039226434261e-05
GO:0032182	ubiquitin-like protein binding	69/6463	120/18639	0.575	1.65827402135231	2.51017567480408e-07	1.5039226434261e-05
GO:0035173	histone kinase activity	171/6463	360/18639	0.475	1.369878539378	2.817759650871e-07	1.57584649046336e-05
GO:0005085	guanyl-nucleotide exchange factor activity	117/6463	230/18639	0.508695652173913	1.46705527786934	2.85893775483194e-07	1.57584649046336e-05
GO:0035091	phosphatidylinositol binding	139/6463	284/18639	0.48943661971831	1.41151309839542	4.36490441792291e-07	2.31339934149914e-05
GO:0044389	ubiquitin-like protein ligase binding	154/6463	322/18639	0.478260869565217	1.37928273987716	6.46918252165441e-07	3.27982813344324e-05
GO:0141003	histone H2AX kinase activity	167/6463	354/18639	0.471751412429379	1.36050975959635	6.66438227405012e-07	3.27982813344324e-05
GO:0031625	ubiquitin protein ligase binding	144/6463	302/18639	0.47682119205298	1.37513077497687	1.82045766745628e-06	8.65031264053362e-05
GO:0043130	ubiquitin binding	57/6463	100/18639	0.57	1.6438542472536	3.93729470969233e-06	0.000177619937075228
GO:0140030	modification-dependent protein binding	89/6463	173/18639	0.514450867052023	1.48365305755573	3.99580409966043e-06	0.000177619937075228
GO:0005201	extracellular matrix structural constituent	86/6463	168/18639	0.511904761904762	1.47631020534471	7.42443144287958e-06	0.000319714579009002
GO:0061665	SUMO ligase activity	13/6463	14/18639	0.928571428571429	2.67795804690436	9.87110566848254e-06	0.000412193442762695
GO:0051018	protein kinase A binding	34/6463	53/18639	0.641509433962264	1.85008422398617	1.12928036773246e-05	0.000457690690216272
GO:0019789	SUMO transferase activity	21/6463	28/18639	0.75	2.16296611480736	1.54986793919542e-05	0.000593255005614249
GO:0051019	mitogen-activated protein kinase binding	21/6463	28/18639	0.75	2.16296611480736	1.54986793919542e-05	0.000593255005614249
GO:0042393	histone binding	117/6463	247/18639	0.473684210526316	1.3660838619836	2.34868439084576e-05	0.000874726240698773
GO:0016922	nuclear receptor binding	71/6463	137/18639	0.518248175182482	1.49460432264061	2.63981902530988e-05	0.000957281741283424
GO:0019902	phosphatase binding	93/6463	190/18639	0.489473684210526	1.41161999071639	3.29383006071341e-05	0.0011638199547854
GO:0035403	histone H3T6 kinase activity	116/6463	247/18639	0.469635627530364	1.35440793153929	4.06597562868495e-05	0.00140072860408196
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	36/6463	60/18639	0.6	1.73037289184589	5.29369172845059e-05	0.00173237718987828
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	17/6463	22/18639	0.772727272727273	2.2285105425288	5.47371263517087e-05	0.00173237718987828
GO:0140857	histone H3T45 kinase activity	115/6463	246/18639	0.467479674796748	1.34819026126204	5.59626963140812e-05	0.00173237718987828
GO:0035402	histone H3T11 kinase activity	115/6463	247/18639	0.465587044534413	1.34273200109499	6.92948031559883e-05	0.00173237718987828
GO:0004676	3-phosphoinositide-dependent protein kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0004711	ribosomal protein S6 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0035175	histone H3S10 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0035979	histone H2AXS139 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0044022	histone H3S28 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0044023	histone H4S1 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0044024	histone H2AS1 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0044025	histone H2BS14 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0072354	histone H3T3 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0072371	histone H2AS121 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0072518	Rho-dependent protein serine/threonine kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0140823	histone H2BS36 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0140855	histone H3S57 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0140995	histone H2A kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0140997	histone H4 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0140998	histone H2B kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:1990244	histone H2AT120 kinase activity	114/6463	245/18639	0.46530612244898	1.34192183449273	7.6687234094757e-05	0.00173237718987828
GO:0004679	AMP-activated protein kinase activity	115/6463	248/18639	0.463709677419355	1.33731775915509	8.55086432763106e-05	0.00190049855539929
GO:0070063	RNA polymerase binding	35/6463	59/18639	0.593220338983051	1.71082065577984	9.30295473722745e-05	0.00203483676633324
GO:0004677	DNA-dependent protein kinase activity	114/6463	246/18639	0.463414634146341	1.33646686768585	9.45856985417034e-05	0.00203654832172605
GO:0004197	cysteine-type endopeptidase activity	48/6463	88/18639	0.545454545454545	1.57306626531445	0.000101756007770045	0.00215722736472496
GO:0140296	general transcription initiation factor binding	32/6463	53/18639	0.60377358490566	1.74125574022228	0.000115232548554057	0.00240591593799229
GO:0034236	protein kinase A catalytic subunit binding	12/6463	14/18639	0.857142857142857	2.47196127406556	0.000126549799511323	0.00260277050338213
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	112/6463	243/18639	0.460905349794239	1.3292302049845	0.000142089803925307	0.00287940808542755
GO:0046915	transition metal ion transmembrane transporter activity	28/6463	45/18639	0.622222222222222	1.79446077672907	0.000146702066563829	0.00289494955273686
GO:0001098	basal transcription machinery binding	35/6463	60/18639	0.583333333333333	1.68230697818351	0.00014915922949515	0.00289494955273686
GO:0001099	basal RNA polymerase II transcription machinery binding	35/6463	60/18639	0.583333333333333	1.68230697818351	0.00014915922949515	0.00289494955273686
GO:0019207	kinase regulator activity	129/6463	287/18639	0.449477351916376	1.29627237542462	0.000183448640281183	0.00350818609454602
GO:0042826	histone deacetylase binding	64/6463	127/18639	0.503937007874016	1.45333156270521	0.000185847303992641	0.00350818609454602
GO:0005543	phospholipid binding	210/6463	497/18639	0.422535211267606	1.2185724590464	0.000228131562518366	0.00424817963716634
GO:0070064	proline-rich region binding	14/6463	18/18639	0.777777777777778	2.24307597091134	0.000232529771685835	0.0042634712267226
GO:0032266	phosphatidylinositol-3-phosphate binding	29/6463	48/18639	0.604166666666667	1.74238937026149	0.000235140648208213	0.0042634712267226
GO:0004713	protein tyrosine kinase activity	69/6463	140/18639	0.492857142857143	1.4213777325877	0.000249628574921909	0.00446737891223884
GO:0001223	transcription coactivator binding	27/6463	44/18639	0.613636363636364	1.76969954847875	0.000267579095292695	0.00472723068350428
GO:0043175	RNA polymerase core enzyme binding	26/6463	42/18639	0.619047619047619	1.7853053646029	0.000283702123665762	0.00494862691660026
GO:0050321	tau-protein kinase activity	16/6463	22/18639	0.727272727272727	2.09742168708593	0.000306082381939526	0.00527226902890833
GO:0017154	semaphorin receptor activity	11/6463	13/18639	0.846153846153846	2.44026946285959	0.000315254929992601	0.00536322584604697
GO:0050431	transforming growth factor beta binding	17/6463	24/18639	0.708333333333333	2.0428013306514	0.000328738790608243	0.00545785606576095
GO:0140033	acetylation-dependent protein binding	17/6463	24/18639	0.708333333333333	2.0428013306514	0.000328738790608243	0.00545785606576095
GO:0046966	nuclear thyroid hormone receptor binding	19/6463	28/18639	0.678571428571429	1.95696934196857	0.000349768622105669	0.00573787096740013
GO:0048156	tau protein binding	26/6463	43/18639	0.604651162790698	1.74378663519353	0.000481852138313715	0.00781167348936823
GO:0008140	cAMP response element binding protein binding	9/6463	10/18639	0.9	2.59555933776884	0.000496872895835209	0.00796152151698742
GO:0004721	phosphoprotein phosphatase activity	82/6463	175/18639	0.468571428571429	1.35133882982251	0.000555385335490341	0.00879679301500793
GO:0051213	dioxygenase activity	48/6463	93/18639	0.516129032258065	1.48849281019001	0.000567867537398301	0.00889228939244158
GO:0070577	lysine-acetylated histone binding	16/6463	23/18639	0.695652173913043	2.00622943982132	0.000681637352189913	0.0105538906889629
GO:0008603	cAMP-dependent protein kinase regulator activity	10/6463	12/18639	0.833333333333333	2.40329568311929	0.000776138232496949	0.0117529503778109
GO:0035497	cAMP response element binding	10/6463	12/18639	0.833333333333333	2.40329568311929	0.000776138232496949	0.0117529503778109
GO:0042578	phosphoric ester hydrolase activity	155/6463	363/18639	0.426997245179063	1.23144076325121	0.000825838418800059	0.0123696232728965
GO:0019887	protein kinase regulator activity	113/6463	255/18639	0.443137254901961	1.27798782208226	0.000840940827985049	0.0124603920533699
GO:0034212	protein N-acetyltransferase activity	30/6463	53/18639	0.566037735849057	1.63242725645839	0.000873274940039465	0.0128018390146211
GO:1901981	phosphatidylinositol phosphate binding	85/6463	185/18639	0.459459459459459	1.32506032258469	0.000951232447256718	0.0137978769717869
GO:0019838	growth factor binding	65/6463	136/18639	0.477941176470588	1.37836075943607	0.00105017829740237	0.0149445240152082
GO:0000993	RNA polymerase II complex binding	22/6463	36/18639	0.611111111111111	1.76241683428748	0.0010628181084836	0.0149445240152082
GO:0005484	SNAP receptor activity	22/6463	36/18639	0.611111111111111	1.76241683428748	0.0010628181084836	0.0149445240152082
GO:0061733	protein-lysine-acetyltransferase activity	27/6463	47/18639	0.574468085106383	1.65674000283117	0.00115195356413785	0.0160342627412319
GO:0005024	transforming growth factor beta receptor activity	12/6463	16/18639	0.75	2.16296611480736	0.00117934157938026	0.01625132696386
GO:0005518	collagen binding	38/6463	72/18639	0.527777777777778	1.52208726597555	0.0011971933412271	0.0163339843981282
GO:0043995	histone H4K5 acetyltransferase activity	19/6463	30/18639	0.633333333333333	1.82650471917066	0.00126295324530495	0.0167341305002906
GO:0043996	histone H4K8 acetyltransferase activity	19/6463	30/18639	0.633333333333333	1.82650471917066	0.00126295324530495	0.0167341305002906
GO:0043997	histone H4K12 acetyltransferase activity	19/6463	30/18639	0.633333333333333	1.82650471917066	0.00126295324530495	0.0167341305002906
GO:0035615	clathrin adaptor activity	13/6463	18/18639	0.722222222222222	2.08285625870339	0.00129521420608136	0.0168677069764187
GO:0035401	histone H3Y41 kinase activity	56/6463	115/18639	0.48695652173913	1.40436060787493	0.00130975663750131	0.0168677069764187
GO:0140801	histone H2AXY142 kinase activity	56/6463	115/18639	0.48695652173913	1.40436060787493	0.00130975663750131	0.0168677069764187
GO:0016004	phospholipase activator activity	14/6463	20/18639	0.7	2.01876837382021	0.00136254676367476	0.0173850874105909
GO:0000149	SNARE binding	52/6463	106/18639	0.490566037735849	1.4147702889306	0.00155585561577795	0.019669440720569
GO:0097493	structural molecule activity conferring elasticity	9/6463	11/18639	0.818181818181818	2.35959939797167	0.0018846075636286	0.0233962993034253
GO:0180030	inositol phosphate kinase activity	9/6463	11/18639	0.818181818181818	2.35959939797167	0.0018846075636286	0.0233962993034253
GO:0010485	histone H4 acetyltransferase activity	21/6463	35/18639	0.6	1.73037289184589	0.00191154686329642	0.0235188533716292
GO:0140034	methylation-dependent protein binding	39/6463	76/18639	0.513157894736842	1.47992418381557	0.00205946313121196	0.0250882832954278
GO:0008080	N-acetyltransferase activity	36/6463	69/18639	0.521739130434783	1.50467207986599	0.00207551835680607	0.0250882832954278
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	198/6463	484/18639	0.409090909090909	1.17979969898584	0.00224123175798249	0.0268558031521727
GO:0035064	methylated histone binding	38/6463	74/18639	0.513513513513513	1.48094977230054	0.00229795268761077	0.027298093133859
GO:0004402	histone acetyltransferase activity	24/6463	42/18639	0.571428571428571	1.64797418271037	0.00235726487531106	0.0277633418647747
GO:0004725	protein tyrosine phosphatase activity	48/6463	98/18639	0.489795918367347	1.41254929946603	0.00240444149117329	0.0280789862274305
GO:0061578	K63-linked deubiquitinase activity	11/6463	15/18639	0.733333333333333	2.11490020114498	0.0025899682080467	0.0299913965604063
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	16/6463	25/18639	0.64	1.84573108463562	0.00261771677738946	0.0300601143270223
GO:0016407	acetyltransferase activity	47/6463	96/18639	0.489583333333333	1.41193621383259	0.00268187773397309	0.0304610163528021
GO:0001216	DNA-binding transcription activator activity	200/6463	491/18639	0.407331975560081	1.174727014152	0.00269683889335403	0.0304610163528021
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	44/6463	89/18639	0.49438202247191	1.42577541650223	0.00284813872958624	0.0316510900755632
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	44/6463	89/18639	0.49438202247191	1.42577541650223	0.00284813872958624	0.0316510900755632
GO:0019003	GDP binding	38/6463	75/18639	0.506666666666667	1.46120377533653	0.00311865468596933	0.0342652083306943
GO:0140463	chromatin-protein adaptor activity	29/6463	54/18639	0.537037037037037	1.54879055134355	0.00313310322907655	0.0342652083306943
GO:0140789	histone phosphatase activity	63/6463	136/18639	0.463235294117647	1.33594965914573	0.00319466717656678	0.0346633966087325
GO:0019210	kinase inhibitor activity	44/6463	90/18639	0.488888888888889	1.40993346742999	0.00372524431560212	0.0397936950922459
GO:0140793	histone H2AXY142 phosphatase activity	44/6463	90/18639	0.488888888888889	1.40993346742999	0.00372524431560212	0.0397936950922459
GO:0001727	lipid kinase activity	23/6463	41/18639	0.560975609756098	1.61782831351445	0.00397672846201603	0.0415146350049855
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	23/6463	41/18639	0.560975609756098	1.61782831351445	0.00397672846201603	0.0415146350049855
GO:0140318	protein transporter activity	23/6463	41/18639	0.560975609756098	1.61782831351445	0.00397672846201603	0.0415146350049855
GO:0016791	phosphatase activity	116/6463	273/18639	0.424908424908425	1.22541669996412	0.00418510540876967	0.0433614680698091
GO:0036408	histone H3K14 acetyltransferase activity	17/6463	28/18639	0.607142857142857	1.75097256912977	0.00430832749869562	0.0439768540237227
GO:0046875	ephrin receptor binding	17/6463	28/18639	0.607142857142857	1.75097256912977	0.00430832749869562	0.0439768540237227
GO:0140313	molecular sequestering activity	29/6463	55/18639	0.527272727272727	1.5206307231373	0.00445664660966813	0.0443110388578052
GO:0004862	cAMP-dependent protein kinase inhibitor activity	8/6463	10/18639	0.8	2.30716385579452	0.00450184719890619	0.0443110388578052
GO:0005381	iron ion transmembrane transporter activity	8/6463	10/18639	0.8	2.30716385579452	0.00450184719890619	0.0443110388578052
GO:0045322	unmethylated CpG binding	8/6463	10/18639	0.8	2.30716385579452	0.00450184719890619	0.0443110388578052
GO:0099122	RNA polymerase II C-terminal domain binding	8/6463	10/18639	0.8	2.30716385579452	0.00450184719890619	0.0443110388578052
GO:0005160	transforming growth factor beta receptor binding	16/6463	26/18639	0.615384615384615	1.77474142753425	0.00462814505299848	0.0449125625565628
GO:0034237	protein kinase A regulatory subunit binding	16/6463	26/18639	0.615384615384615	1.77474142753425	0.00462814505299848	0.0449125625565628
GO:0035035	histone acetyltransferase binding	15/6463	24/18639	0.625	1.80247176233947	0.00493918774030424	0.0475958091338408
GO:0004860	protein kinase inhibitor activity	41/6463	84/18639	0.488095238095238	1.40764461439844	0.00518332812322779	0.0496015705125548
GO:0001046	core promoter sequence-specific DNA binding	24/6463	44/18639	0.545454545454545	1.57306626531445	0.00533937502092532	0.0504244450503532
GO:0140566	histone reader activity	20/6463	35/18639	0.571428571428571	1.64797418271037	0.0053425028863219	0.0504244450503532
GO:0008234	cysteine-type peptidase activity	82/6463	187/18639	0.438502673796791	1.26462189956652	0.00559081173169933	0.0524091058930727
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	12/6463	18/18639	0.666666666666667	1.92263654649544	0.00563927247258689	0.0525061991028699
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	11/6463	16/18639	0.6875	1.98271893857342	0.00569334679111286	0.0526539052225069
GO:0097110	scaffold protein binding	35/6463	70/18639	0.5	1.44197740987158	0.00583603085297866	0.0529513665530126
GO:0019903	protein phosphatase binding	65/6463	144/18639	0.451388888888889	1.30178516168962	0.00584002706409704	0.0529513665530126
GO:0071889	14-3-3 protein binding	19/6463	33/18639	0.575757575757576	1.66045883560969	0.00587921558970314	0.0529513665530126
GO:0140416	transcription regulator inhibitor activity	19/6463	33/18639	0.575757575757576	1.66045883560969	0.00587921558970314	0.0529513665530126
GO:0001222	transcription corepressor binding	26/6463	49/18639	0.530612244897959	1.5302617410882	0.00619706286091288	0.0554516404047919
GO:0140457	protein demethylase activity	18/6463	31/18639	0.580645161290323	1.67455441146377	0.00645790048573562	0.0574128185118947
GO:0032451	demethylase activity	22/6463	40/18639	0.55	1.58617515085873	0.00659990857367643	0.0582991924008085
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	17/6463	29/18639	0.586206896551724	1.69059420467702	0.00707736143688814	0.0613371324530305
GO:0010484	histone H3 acetyltransferase activity	17/6463	29/18639	0.586206896551724	1.69059420467702	0.00707736143688814	0.0613371324530305
GO:0097472	cyclin-dependent protein kinase activity	17/6463	29/18639	0.586206896551724	1.69059420467702	0.00707736143688814	0.0613371324530305
GO:0004715	non-membrane spanning protein tyrosine kinase activity	24/6463	45/18639	0.533333333333333	1.53810923719635	0.00772599396044558	0.0661965484101293
GO:0023026	MHC class II protein complex binding	16/6463	27/18639	0.592592592592593	1.7090102635515	0.0077341395457408	0.0661965484101293
GO:0003924	GTPase activity	136/6463	331/18639	0.410876132930514	1.18494820388238	0.00839700758206841	0.0703314011302066
GO:0000030	mannosyltransferase activity	15/6463	25/18639	0.6	1.73037289184589	0.00842139418467641	0.0703314011302066
GO:0017025	TBP-class protein binding	15/6463	25/18639	0.6	1.73037289184589	0.00842139418467641	0.0703314011302066
GO:0042974	nuclear retinoic acid receptor binding	15/6463	25/18639	0.6	1.73037289184589	0.00842139418467641	0.0703314011302066
GO:0044013	histone H2B acetyltransferase activity	14/6463	23/18639	0.608695652173913	1.75545075984366	0.00912725778746839	0.0757672363321171
GO:0019955	cytokine binding	64/6463	144/18639	0.444444444444444	1.28175769766362	0.00934850374971887	0.0771391507012731
GO:0038187	pattern recognition receptor activity	25/6463	48/18639	0.520833333333333	1.50205980194956	0.00974859473715932	0.0797002256662035
GO:0051010	microtubule plus-end binding	13/6463	21/18639	0.619047619047619	1.7853053646029	0.00983239358726749	0.0797002256662035
GO:0140312	cargo adaptor activity	13/6463	21/18639	0.619047619047619	1.7853053646029	0.00983239358726749	0.0797002256662035
GO:0030291	protein serine/threonine kinase inhibitor activity	24/6463	46/18639	0.521739130434783	1.50467207986599	0.0109172015211547	0.087844614950494
GO:0008429	phosphatidylethanolamine binding	11/6463	17/18639	0.647058823529412	1.86608841277498	0.011101887589695	0.087844614950494
GO:0046965	nuclear retinoid X receptor binding	11/6463	17/18639	0.647058823529412	1.86608841277498	0.011101887589695	0.087844614950494
GO:0032452	histone demethylase activity	17/6463	30/18639	0.566666666666667	1.63424106452112	0.0111148654087024	0.087844614950494
GO:0032794	GTPase activating protein binding	8/6463	11/18639	0.727272727272727	2.09742168708593	0.0114811528929797	0.087844614950494
GO:0048185	activin binding	8/6463	11/18639	0.727272727272727	2.09742168708593	0.0114811528929797	0.087844614950494
GO:0048407	platelet-derived growth factor binding	8/6463	11/18639	0.727272727272727	2.09742168708593	0.0114811528929797	0.087844614950494
GO:0140031	phosphorylation-dependent protein binding	8/6463	11/18639	0.727272727272727	2.09742168708593	0.0114811528929797	0.087844614950494
GO:0042809	nuclear vitamin D receptor binding	10/6463	15/18639	0.666666666666667	1.92263654649544	0.011546627549597	0.087844614950494
GO:0050780	dopamine receptor binding	10/6463	15/18639	0.666666666666667	1.92263654649544	0.011546627549597	0.087844614950494
GO:0120283	protein serine/threonine kinase binding	10/6463	15/18639	0.666666666666667	1.92263654649544	0.011546627549597	0.087844614950494
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	9/6463	13/18639	0.692307692307692	1.99658410597603	0.0117296147684259	0.087844614950494
GO:0051011	microtubule minus-end binding	9/6463	13/18639	0.692307692307692	1.99658410597603	0.0117296147684259	0.087844614950494
GO:0070123	transforming growth factor beta receptor activity, type III	9/6463	13/18639	0.692307692307692	1.99658410597603	0.0117296147684259	0.087844614950494
GO:0023023	MHC protein complex binding	20/6463	37/18639	0.540540540540541	1.55889449715846	0.01202646371915	0.089580902729669
GO:0019199	transmembrane receptor protein kinase activity	37/6463	78/18639	0.474358974358974	1.36802985039098	0.0133298809094459	0.0980761316530737
GO:0001540	amyloid-beta binding	39/6463	83/18639	0.469879518072289	1.35511130084317	0.0135364573739388	0.0980761316530737
GO:0004112	cyclic-nucleotide phosphodiesterase activity	15/6463	26/18639	0.576923076923077	1.66382008831336	0.0135940066369645	0.0980761316530737
GO:0050681	nuclear androgen receptor binding	15/6463	26/18639	0.576923076923077	1.66382008831336	0.0135940066369645	0.0980761316530737
GO:0050750	low-density lipoprotein particle receptor binding	15/6463	26/18639	0.576923076923077	1.66382008831336	0.0135940066369645	0.0980761316530737
GO:0070412	R-SMAD binding	15/6463	26/18639	0.576923076923077	1.66382008831336	0.0135940066369645	0.0980761316530737
GO:0000287	magnesium ion binding	96/6463	230/18639	0.417391304347826	1.20373766389279	0.0149000878953741	0.104470549737695
GO:0140767	enzyme-substrate adaptor activity	61/6463	139/18639	0.438848920863309	1.26562046046282	0.0149127667982578	0.104470549737695
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	14/6463	24/18639	0.583333333333333	1.68230697818351	0.0149905558534983	0.104470549737695
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	14/6463	24/18639	0.583333333333333	1.68230697818351	0.0149905558534983	0.104470549737695
GO:0043998	histone H2A acetyltransferase activity	14/6463	24/18639	0.583333333333333	1.68230697818351	0.0149905558534983	0.104470549737695
GO:0060229	lipase activator activity	14/6463	24/18639	0.583333333333333	1.68230697818351	0.0149905558534983	0.104470549737695
GO:0140311	protein sequestering activity	18/6463	33/18639	0.545454545454545	1.57306626531445	0.0150110078723249	0.104470549737695
GO:0004177	aminopeptidase activity	21/6463	40/18639	0.525	1.51407628036516	0.0153692315342557	0.10565693886406
GO:0042277	peptide binding	103/6463	249/18639	0.413654618473896	1.19296123065681	0.0159731054738264	0.10565693886406
GO:0002039	p53 binding	33/6463	69/18639	0.478260869565217	1.37928273987716	0.0163017014635211	0.10565693886406
GO:0032931	histone H3K56 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0043992	histone H3K9 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0043993	histone H3K18 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0043994	histone H3K23 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0043999	histone H2AK5 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0044012	histone H2AK9 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0044014	histone H2BK5 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0044015	histone H2BK12 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0044016	histone H3K4 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0044017	histone H3K27 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0044018	histone H3K36 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0046972	histone H4K16 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0140035	ubiquitin-like protein reader activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0140908	histone H3K122 acetyltransferase activity	13/6463	22/18639	0.590909090909091	1.70415512075732	0.0164849360346684	0.10565693886406
GO:0019783	ubiquitin-like protein peptidase activity	56/6463	127/18639	0.440944881889764	1.27166511736706	0.0171310584114729	0.109289807828749
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	95/6463	229/18639	0.414847161572052	1.19640047107249	0.0183871474454124	0.116500605610043
GO:0019209	kinase activator activity	64/6463	148/18639	0.432432432432432	1.24711559772677	0.0184304296248108	0.116500605610043
GO:0005178	integrin binding	69/6463	161/18639	0.428571428571429	1.23598063703278	0.0185888529139724	0.116965476326274
GO:0016417	S-acyltransferase activity	16/6463	29/18639	0.551724137931034	1.59114748675484	0.0187320766401554	0.117330916409701
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	56/6463	128/18639	0.4375	1.26173023363763	0.020363399276501	0.126700943582936
GO:0038024	cargo receptor activity	31/6463	65/18639	0.476923076923077	1.37542460633904	0.0204119081824468	0.126700943582936
GO:0005044	scavenger receptor activity	15/6463	27/18639	0.555555555555556	1.60219712207953	0.0209188405009941	0.128688224153437
GO:0005385	zinc ion transmembrane transporter activity	15/6463	27/18639	0.555555555555556	1.60219712207953	0.0209188405009941	0.128688224153437
GO:0005159	insulin-like growth factor receptor binding	10/6463	16/18639	0.625	1.80247176233947	0.0213020954804039	0.128700301032662
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	10/6463	16/18639	0.625	1.80247176233947	0.0213020954804039	0.128700301032662
GO:0034450	ubiquitin-ubiquitin ligase activity	10/6463	16/18639	0.625	1.80247176233947	0.0213020954804039	0.128700301032662
GO:0097027	ubiquitin-protein transferase activator activity	10/6463	16/18639	0.625	1.80247176233947	0.0213020954804039	0.128700301032662
GO:0042169	SH2 domain binding	21/6463	41/18639	0.51219512195122	1.47714759060015	0.0213877858755295	0.128700301032662
GO:0008175	tRNA methyltransferase activity	18/6463	34/18639	0.529411764705882	1.52679961045226	0.0217256801120638	0.129601676166337
GO:0030332	cyclin binding	18/6463	34/18639	0.529411764705882	1.52679961045226	0.0217256801120638	0.129601676166337
GO:0004722	protein serine/threonine phosphatase activity	46/6463	103/18639	0.446601941747573	1.28797982240956	0.0224771822443238	0.131100807580776
GO:0005161	platelet-derived growth factor receptor binding	9/6463	14/18639	0.642857142857143	1.85397095554917	0.0228069829721783	0.131100807580776
GO:0005545	1-phosphatidylinositol binding	9/6463	14/18639	0.642857142857143	1.85397095554917	0.0228069829721783	0.131100807580776
GO:0042813	Wnt receptor activity	9/6463	14/18639	0.642857142857143	1.85397095554917	0.0228069829721783	0.131100807580776
GO:0030145	manganese ion binding	32/6463	68/18639	0.470588235294118	1.3571552092909	0.023215593162247	0.131100807580776
GO:0032934	sterol binding	32/6463	68/18639	0.470588235294118	1.3571552092909	0.023215593162247	0.131100807580776
GO:0017056	structural constituent of nuclear pore	14/6463	25/18639	0.56	1.61501469905617	0.0233513070683623	0.131100807580776
GO:0019211	phosphatase activator activity	14/6463	25/18639	0.56	1.61501469905617	0.0233513070683623	0.131100807580776
GO:0019706	protein-cysteine S-palmitoyltransferase activity	14/6463	25/18639	0.56	1.61501469905617	0.0233513070683623	0.131100807580776
GO:0019707	protein-cysteine S-acyltransferase activity	14/6463	25/18639	0.56	1.61501469905617	0.0233513070683623	0.131100807580776
GO:0005025	transforming growth factor beta receptor activity, type I	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0005026	transforming growth factor beta receptor activity, type II	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0005247	voltage-gated chloride channel activity	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0016361	activin receptor activity, type I	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0016362	activin receptor activity, type II	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0017002	activin receptor activity	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0034452	dynactin binding	8/6463	12/18639	0.666666666666667	1.92263654649544	0.0240234275648921	0.131100807580776
GO:0035591	signaling adaptor activity	56/6463	129/18639	0.434108527131783	1.25194937911331	0.0240693811993403	0.131100807580776
GO:0005048	signal sequence binding	25/6463	51/18639	0.490196078431373	1.41370334301135	0.0241462935107423	0.131100807580776
GO:0022884	macromolecule transmembrane transporter activity	17/6463	32/18639	0.53125	1.53210099798855	0.0244081019926219	0.131100807580776
GO:0005522	profilin binding	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:0032395	MHC class II receptor activity	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:0042975	peroxisome proliferator activated receptor binding	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:0043422	protein kinase B binding	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:0140999	histone H3K4 trimethyltransferase activity	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:1905394	retromer complex binding	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:1990757	ubiquitin ligase activator activity	7/6463	10/18639	0.7	2.01876837382021	0.0246408629632953	0.131100807580776
GO:0019905	syntaxin binding	29/6463	61/18639	0.475409836065574	1.37106048807461	0.0255935896408588	0.134950325818823
GO:0043014	alpha-tubulin binding	22/6463	44/18639	0.5	1.44197740987158	0.0258262094727607	0.134950325818823
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	13/6463	23/18639	0.565217391304348	1.63006141985483	0.0260499177560283	0.134950325818823
GO:0005158	insulin receptor binding	13/6463	23/18639	0.565217391304348	1.63006141985483	0.0260499177560283	0.134950325818823
GO:0042171	lysophosphatidic acid acyltransferase activity	13/6463	23/18639	0.565217391304348	1.63006141985483	0.0260499177560283	0.134950325818823
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	13/6463	23/18639	0.565217391304348	1.63006141985483	0.0260499177560283	0.134950325818823
GO:0071617	lysophospholipid acyltransferase activity	13/6463	23/18639	0.565217391304348	1.63006141985483	0.0260499177560283	0.134950325818823
GO:0016763	pentosyltransferase activity	24/6463	49/18639	0.489795918367347	1.41254929946603	0.0271326372672228	0.140032862000873
GO:0001968	fibronectin binding	16/6463	30/18639	0.533333333333333	1.53810923719635	0.0274374609046731	0.141077690771043
GO:0016757	glycosyltransferase activity	108/6463	267/18639	0.404494382022472	1.16654352259274	0.0276307643528064	0.141543469435566
GO:0031593	polyubiquitin modification-dependent protein binding	28/6463	59/18639	0.474576271186441	1.36865652462387	0.028674899410659	0.145808160102908
GO:0045309	protein phosphorylated amino acid binding	28/6463	59/18639	0.474576271186441	1.36865652462387	0.028674899410659	0.145808160102908
GO:0140938	histone H3 methyltransferase activity	23/6463	47/18639	0.48936170212766	1.41129703944878	0.0305076935828127	0.154557359401162
GO:0141052	histone H3 demethylase activity	15/6463	28/18639	0.535714285714286	1.54497579629097	0.0308614769154477	0.155776978716069
GO:0042800	histone H3K4 methyltransferase activity	11/6463	19/18639	0.578947368421053	1.66965805353551	0.0323080400919741	0.161892651806329
GO:1990380	K48-linked deubiquitinase activity	11/6463	19/18639	0.578947368421053	1.66965805353551	0.0323080400919741	0.161892651806329
GO:0050840	extracellular matrix binding	31/6463	67/18639	0.462686567164179	1.33436715540355	0.0326096436990514	0.162811916729322
GO:0031072	heat shock protein binding	56/6463	131/18639	0.427480916030534	1.23283564813448	0.0330810638124629	0.164569335500267
GO:0030295	protein kinase activator activity	59/6463	139/18639	0.424460431654676	1.22412470766076	0.0340185245752875	0.168624197355202
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	14/6463	26/18639	0.538461538461538	1.55289874909247	0.0347348242383265	0.169732580852532
GO:0008157	protein phosphatase 1 binding	14/6463	26/18639	0.538461538461538	1.55289874909247	0.0347348242383265	0.169732580852532
GO:0052742	phosphatidylinositol kinase activity	14/6463	26/18639	0.538461538461538	1.55289874909247	0.0347348242383265	0.169732580852532
GO:0097602	cullin family protein binding	14/6463	26/18639	0.538461538461538	1.55289874909247	0.0347348242383265	0.169732580852532
GO:0015605	organophosphate ester transmembrane transporter activity	24/6463	50/18639	0.48	1.38429831347671	0.0353892215000205	0.171646268719219
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	10/6463	17/18639	0.588235294117647	1.69644401161362	0.0358738210385596	0.171646268719219
GO:0015278	intracellularly gated calcium channel activity	10/6463	17/18639	0.588235294117647	1.69644401161362	0.0358738210385596	0.171646268719219
GO:0016805	dipeptidase activity	10/6463	17/18639	0.588235294117647	1.69644401161362	0.0358738210385596	0.171646268719219
GO:0019198	transmembrane receptor protein phosphatase activity	10/6463	17/18639	0.588235294117647	1.69644401161362	0.0358738210385596	0.171646268719219
GO:0032977	membrane insertase activity	10/6463	17/18639	0.588235294117647	1.69644401161362	0.0358738210385596	0.171646268719219
GO:0051219	phosphoprotein binding	41/6463	93/18639	0.440860215053763	1.2714209420373	0.0373446236364753	0.178065368065962
GO:0004712	protein serine/threonine/tyrosine kinase activity	21/6463	43/18639	0.488372093023256	1.40844305150247	0.0386515449268103	0.183181273140246
GO:0017147	Wnt-protein binding	16/6463	31/18639	0.516129032258065	1.48849281019001	0.0388163510572946	0.183181273140246
GO:0070325	lipoprotein particle receptor binding	16/6463	31/18639	0.516129032258065	1.48849281019001	0.0388163510572946	0.183181273140246
GO:0001091	RNA polymerase II general transcription initiation factor binding	13/6463	24/18639	0.541666666666667	1.56214219402754	0.0391200727317457	0.183984505885138
GO:0005041	low-density lipoprotein particle receptor activity	9/6463	15/18639	0.6	1.73037289184589	0.0396975161060501	0.184185781798441
GO:0005523	tropomyosin binding	9/6463	15/18639	0.6	1.73037289184589	0.0396975161060501	0.184185781798441
GO:0141050	histone H3K deacetylase activity	9/6463	15/18639	0.6	1.73037289184589	0.0396975161060501	0.184185781798441
GO:0141051	histone H4K deacetylase activity	9/6463	15/18639	0.6	1.73037289184589	0.0396975161060501	0.184185781798441
GO:0140223	general transcription initiation factor activity	31/6463	68/18639	0.455882352941176	1.31474410900056	0.0404803346893469	0.187187587925906
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	52/6463	122/18639	0.426229508196721	1.22922664448069	0.0410614183524091	0.189239580232842
GO:0016409	palmitoyltransferase activity	18/6463	36/18639	0.5	1.44197740987158	0.0416573239756895	0.191345974795
GO:1990782	protein tyrosine kinase binding	50/6463	117/18639	0.427350427350427	1.23245932467656	0.0423901906309079	0.194065390994655
GO:0030971	receptor tyrosine kinase binding	36/6463	81/18639	0.444444444444444	1.28175769766362	0.0431399443878073	0.196122741492084
GO:0005338	nucleotide-sugar transmembrane transporter activity	8/6463	13/18639	0.615384615384615	1.77474142753425	0.0436935280392379	0.196122741492084
GO:0035673	oligopeptide transmembrane transporter activity	8/6463	13/18639	0.615384615384615	1.77474142753425	0.0436935280392379	0.196122741492084
GO:0046974	histone H3K9 methyltransferase activity	8/6463	13/18639	0.615384615384615	1.77474142753425	0.0436935280392379	0.196122741492084
GO:0070700	BMP receptor binding	8/6463	13/18639	0.615384615384615	1.77474142753425	0.0436935280392379	0.196122741492084
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	8/6463	13/18639	0.615384615384615	1.77474142753425	0.0436935280392379	0.196122741492084
GO:0004407	histone deacetylase activity	12/6463	22/18639	0.545454545454545	1.57306626531445	0.0440886044126807	0.196615200261081
GO:0033558	protein lysine deacetylase activity	12/6463	22/18639	0.545454545454545	1.57306626531445	0.0440886044126807	0.196615200261081
GO:0016410	N-acyltransferase activity	41/6463	94/18639	0.436170212765957	1.25789518733478	0.0445569882652938	0.198062999450242
GO:0003779	actin binding	171/6463	443/18639	0.386004514672686	1.11321958053291	0.0447490054316086	0.198276943680889
GO:0008238	exopeptidase activity	44/6463	102/18639	0.431372549019608	1.24405894184999	0.0464742478593413	0.204864960322608
GO:0017124	SH3 domain binding	49/6463	115/18639	0.426086956521739	1.22881553189056	0.0465331876494749	0.204864960322608
GO:0002020	protease binding	57/6463	136/18639	0.419117647058824	1.2087163582747	0.0469590398722415	0.205923981184912
GO:0003953	NAD+ nucleosidase activity	7/6463	11/18639	0.636363636363636	1.83524397620019	0.0476703555863475	0.205923981184912
GO:0005114	type II transforming growth factor beta receptor binding	7/6463	11/18639	0.636363636363636	1.83524397620019	0.0476703555863475	0.205923981184912
GO:0008432	JUN kinase binding	7/6463	11/18639	0.636363636363636	1.83524397620019	0.0476703555863475	0.205923981184912
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	7/6463	11/18639	0.636363636363636	1.83524397620019	0.0476703555863475	0.205923981184912
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	7/6463	11/18639	0.636363636363636	1.83524397620019	0.0476703555863475	0.205923981184912
GO:0008081	phosphoric diester hydrolase activity	38/6463	87/18639	0.436781609195402	1.25965842701425	0.0505567920137104	0.21771018560904
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	25/6463	54/18639	0.462962962962963	1.33516426839961	0.0510997948125612	0.219362982092552
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	36/6463	82/18639	0.439024390243902	1.2661265062287	0.0518640018148171	0.221952156834838
GO:0019213	deacetylase activity	18/6463	37/18639	0.486486486486487	1.40300504744262	0.0554698730621685	0.236648560618168
GO:0016854	racemase and epimerase activity	10/6463	18/18639	0.555555555555556	1.60219712207953	0.0561086010124637	0.237569322798055
GO:0030228	lipoprotein particle receptor activity	10/6463	18/18639	0.555555555555556	1.60219712207953	0.0561086010124637	0.237569322798055
GO:0008139	nuclear localization sequence binding	13/6463	25/18639	0.52	1.49965650626644	0.0562029022004107	0.237569322798055
GO:0048487	beta-tubulin binding	20/6463	42/18639	0.476190476190476	1.37331181892531	0.0567295697533706	0.237793011062831
GO:0016504	peptidase activator activity	26/6463	57/18639	0.456140350877193	1.31548816339161	0.0568977083577959	0.237793011062831
GO:0001784	phosphotyrosine residue binding	22/6463	47/18639	0.468085106382979	1.34993629860318	0.0572698648965514	0.237793011062831
GO:0005080	protein kinase C binding	24/6463	52/18639	0.461538461538462	1.33105607065069	0.0572801943622541	0.237793011062831
GO:0030159	signaling receptor complex adaptor activity	24/6463	52/18639	0.461538461538462	1.33105607065069	0.0572801943622541	0.237793011062831
GO:0140597	protein carrier chaperone	76/6463	188/18639	0.404255319148936	1.16585407606638	0.05729120440701	0.237793011062831
GO:0008201	heparin binding	70/6463	172/18639	0.406976744186047	1.17370254291873	0.0574801298093953	0.23786071734939
GO:0005525	GTP binding	146/6463	378/18639	0.386243386243386	1.11390847535053	0.0584076960539424	0.240975464557882
GO:0001965	G-protein alpha-subunit binding	15/6463	30/18639	0.5	1.44197740987158	0.0602770649447055	0.247207724683941
GO:0035925	mRNA 3'-UTR AU-rich region binding	15/6463	30/18639	0.5	1.44197740987158	0.0602770649447055	0.247207724683941
GO:0160215	deacylase activity	29/6463	65/18639	0.446153846153846	1.28668753496233	0.0616230007106234	0.251977729908721
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	36/6463	83/18639	0.433734939759036	1.25087197000908	0.0618131876589492	0.252007611224947
GO:0019208	phosphatase regulator activity	49/6463	117/18639	0.418803418803419	1.20781013818303	0.0625360869538204	0.253763391593947
GO:0098531	ligand-modulated transcription factor activity	27/6463	60/18639	0.45	1.29777966888442	0.0627496147496225	0.253763391593947
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	9/6463	16/18639	0.5625	1.62222458610552	0.0633487711961666	0.253763391593947
GO:0005521	lamin binding	9/6463	16/18639	0.5625	1.62222458610552	0.0633487711961666	0.253763391593947
GO:0015923	mannosidase activity	9/6463	16/18639	0.5625	1.62222458610552	0.0633487711961666	0.253763391593947
GO:0070411	I-SMAD binding	9/6463	16/18639	0.5625	1.62222458610552	0.0633487711961666	0.253763391593947
GO:0043274	phospholipase binding	12/6463	23/18639	0.521739130434783	1.50467207986599	0.0637671716744834	0.253962897593752
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	12/6463	23/18639	0.521739130434783	1.50467207986599	0.0637671716744834	0.253962897593752
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	19/6463	40/18639	0.475	1.369878539378	0.0639562720825287	0.253981968097189
GO:0043539	protein serine/threonine kinase activator activity	32/6463	73/18639	0.438356164383562	1.26419937303809	0.065371270066812	0.258855201586399
GO:0044325	transmembrane transporter binding	56/6463	136/18639	0.411764705882353	1.18751080812953	0.0669880316089047	0.261743601782165
GO:1990841	promoter-specific chromatin binding	30/6463	68/18639	0.441176470588235	1.27233300871021	0.0670574314818782	0.261743601782165
GO:0140104	molecular carrier activity	98/6463	249/18639	0.393574297188755	1.13505049130453	0.0682878071696428	0.261743601782165
GO:0033192	calmodulin-dependent protein phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0140791	histone H2AXS140 phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:1990439	MAP kinase serine/threonine phosphatase activity	35/6463	81/18639	0.432098765432099	1.24615331717297	0.0683267921990152	0.261743601782165
GO:0101005	deubiquitinase activity	48/6463	115/18639	0.417391304347826	1.20373766389279	0.0683800411041939	0.261743601782165
GO:0016251	RNA polymerase II general transcription initiation factor activity	24/6463	53/18639	0.452830188679245	1.30594180516671	0.0712229221876615	0.269937098498413
GO:1901505	carbohydrate derivative transmembrane transporter activity	24/6463	53/18639	0.452830188679245	1.30594180516671	0.0712229221876615	0.269937098498413
GO:0046030	inositol trisphosphate phosphatase activity	8/6463	14/18639	0.571428571428571	1.64797418271037	0.0715422547953175	0.269937098498413
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	8/6463	14/18639	0.571428571428571	1.64797418271037	0.0715422547953175	0.269937098498413
GO:0098821	BMP receptor activity	8/6463	14/18639	0.571428571428571	1.64797418271037	0.0715422547953175	0.269937098498413
GO:0140693	molecular condensate scaffold activity	22/6463	48/18639	0.458333333333333	1.32181262571561	0.0720696902141642	0.269937098498413
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	11/6463	21/18639	0.523809523809524	1.51064300081784	0.0724794821802706	0.269937098498413
GO:0005123	death receptor binding	11/6463	21/18639	0.523809523809524	1.51064300081784	0.0724794821802706	0.269937098498413
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	11/6463	21/18639	0.523809523809524	1.51064300081784	0.0724794821802706	0.269937098498413
GO:0072542	protein phosphatase activator activity	11/6463	21/18639	0.523809523809524	1.51064300081784	0.0724794821802706	0.269937098498413
GO:0061775	cohesin loader activity	62/6463	153/18639	0.405228758169935	1.16866143022272	0.0759427035839202	0.281325866802067
GO:0005539	glycosaminoglycan binding	95/6463	242/18639	0.392561983471074	1.13213102427934	0.0759457347245057	0.281325866802067
GO:0005516	calmodulin binding	82/6463	207/18639	0.396135265700483	1.14243620878714	0.0776295093536912	0.283952560043314
GO:0043548	phosphatidylinositol 3-kinase binding	13/6463	26/18639	0.5	1.44197740987158	0.0776709801624952	0.283952560043314
GO:0070006	metalloaminopeptidase activity	13/6463	26/18639	0.5	1.44197740987158	0.0776709801624952	0.283952560043314
GO:0004843	cysteine-type deubiquitinase activity	45/6463	108/18639	0.416666666666667	1.20164784155965	0.07769499681957	0.283952560043314
GO:0005496	steroid binding	45/6463	108/18639	0.416666666666667	1.20164784155965	0.07769499681957	0.283952560043314
GO:0030544	Hsp70 protein binding	23/6463	51/18639	0.450980392156863	1.30060707557044	0.0797224153985496	0.283952560043314
GO:0033549	MAP kinase phosphatase activity	35/6463	82/18639	0.426829268292683	1.23095632550013	0.0805863169532053	0.283952560043314
GO:0000995	RNA polymerase III general transcription initiation factor activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0005095	GTPase inhibitor activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0016423	tRNA (guanine) methyltransferase activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0035014	phosphatidylinositol 3-kinase regulator activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0035259	nuclear glucocorticoid receptor binding	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0070410	co-SMAD binding	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0097677	STAT family protein binding	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0141221	histone deacetylase activity, hydrolytic mechanism	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	7/6463	12/18639	0.583333333333333	1.68230697818351	0.0807760548163853	0.283952560043314
GO:0044390	ubiquitin-like protein conjugating enzyme binding	17/6463	36/18639	0.472222222222222	1.3618675537676	0.0815200063610088	0.285838597367608
GO:0097001	ceramide binding	10/6463	19/18639	0.526315789473684	1.51787095775955	0.0825536687018965	0.287997355623325
GO:0140036	ubiquitin-modified protein reader activity	10/6463	19/18639	0.526315789473684	1.51787095775955	0.0825536687018965	0.287997355623325
GO:0004879	nuclear receptor activity	26/6463	59/18639	0.440677966101695	1.27089534429359	0.0851470195389361	0.296294426577409
GO:0003925	G protein activity	24/6463	54/18639	0.444444444444444	1.28175769766362	0.087321424087742	0.300787047500072
GO:0015485	cholesterol binding	24/6463	54/18639	0.444444444444444	1.28175769766362	0.087321424087742	0.300787047500072
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	24/6463	54/18639	0.444444444444444	1.28175769766362	0.087321424087742	0.300787047500072
GO:0050661	NADP binding	24/6463	54/18639	0.444444444444444	1.28175769766362	0.087321424087742	0.300787047500072
GO:0030020	extracellular matrix structural constituent conferring tensile strength	20/6463	44/18639	0.454545454545455	1.31088855442871	0.0908562226100548	0.300787047500072
GO:0004445	inositol-polyphosphate 5-phosphatase activity	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0005131	growth hormone receptor binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0008190	eukaryotic initiation factor 4E binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0008239	dipeptidyl-peptidase activity	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0031434	mitogen-activated protein kinase kinase binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0051864	histone H3K36 demethylase activity	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0070097	delta-catenin binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0070513	death domain binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:1990763	arrestin family protein binding	6/6463	10/18639	0.6	1.73037289184589	0.0910829286400554	0.300787047500072
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	14/6463	29/18639	0.482758620689655	1.39225405091049	0.0912401929281787	0.300787047500072
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	18/6463	39/18639	0.461538461538462	1.33105607065069	0.0919180743904051	0.302298583556034
GO:0003725	double-stranded RNA binding	32/6463	75/18639	0.426666666666667	1.23048738975708	0.0921406246720685	0.302309001900263
GO:0004518	nuclease activity	82/6463	209/18639	0.392344497607655	1.1315038048753	0.0942532762874701	0.305617995741524
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	9/6463	17/18639	0.529411764705882	1.52679961045226	0.0942580901234745	0.305617995741524
GO:0005092	GDP-dissociation inhibitor activity	9/6463	17/18639	0.529411764705882	1.52679961045226	0.0942580901234745	0.305617995741524
GO:0008484	sulfuric ester hydrolase activity	9/6463	17/18639	0.529411764705882	1.52679961045226	0.0942580901234745	0.305617995741524
GO:0030169	low-density lipoprotein particle binding	9/6463	17/18639	0.529411764705882	1.52679961045226	0.0942580901234745	0.305617995741524
GO:0004386	helicase activity	62/6463	155/18639	0.4	1.15358192789726	0.0953107199910135	0.308305568421635
GO:0070851	growth factor receptor binding	56/6463	139/18639	0.402877697841727	1.16188107845767	0.0966728049442417	0.31197921595589
GO:0030021	extracellular matrix structural constituent conferring compression resistance	11/6463	22/18639	0.5	1.44197740987158	0.100870359947861	0.324764850486337
GO:0043394	proteoglycan binding	17/6463	37/18639	0.459459459459459	1.32506032258469	0.103662619665023	0.332157435591123
GO:0008320	protein transmembrane transporter activity	13/6463	27/18639	0.481481481481481	1.38857083913559	0.103724284069034	0.332157435591123
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	15/6463	32/18639	0.46875	1.3518538217546	0.1043716760602	0.332157435591123
GO:0120015	sterol transfer activity	15/6463	32/18639	0.46875	1.3518538217546	0.1043716760602	0.332157435591123
GO:0140142	nucleocytoplasmic carrier activity	15/6463	32/18639	0.46875	1.3518538217546	0.1043716760602	0.332157435591123
GO:0004559	alpha-mannosidase activity	8/6463	15/18639	0.533333333333333	1.53810923719635	0.107936241868766	0.338806699988973
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	8/6463	15/18639	0.533333333333333	1.53810923719635	0.107936241868766	0.338806699988973
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	8/6463	15/18639	0.533333333333333	1.53810923719635	0.107936241868766	0.338806699988973
GO:0004953	icosanoid receptor activity	8/6463	15/18639	0.533333333333333	1.53810923719635	0.107936241868766	0.338806699988973
GO:0031005	filamin binding	8/6463	15/18639	0.533333333333333	1.53810923719635	0.107936241868766	0.338806699988973
GO:0051371	muscle alpha-actinin binding	8/6463	15/18639	0.533333333333333	1.53810923719635	0.107936241868766	0.338806699988973
GO:0017018	myosin phosphatase activity	35/6463	84/18639	0.416666666666667	1.20164784155965	0.109429860752035	0.342714427537054
GO:0000510	H3-H4 histone complex chaperone activity	60/6463	151/18639	0.397350993377483	1.14594231248072	0.110801672508797	0.343884470083608
GO:0140584	chromatin extrusion motor activity	60/6463	151/18639	0.397350993377483	1.14594231248072	0.110801672508797	0.343884470083608
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	60/6463	151/18639	0.397350993377483	1.14594231248072	0.110801672508797	0.343884470083608
GO:0140849	ATP-dependent H2AZ histone chaperone activity	60/6463	151/18639	0.397350993377483	1.14594231248072	0.110801672508797	0.343884470083608
GO:0061791	GTPase motor activity	18/6463	40/18639	0.45	1.29777966888442	0.114795912642304	0.354124608103598
GO:1990606	membrane scission GTPase motor activity	18/6463	40/18639	0.45	1.29777966888442	0.114795912642304	0.354124608103598
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	10/6463	20/18639	0.5	1.44197740987158	0.115386029781216	0.354124608103598
GO:0031418	L-ascorbic acid binding	10/6463	20/18639	0.5	1.44197740987158	0.115386029781216	0.354124608103598
GO:0052745	inositol phosphate phosphatase activity	10/6463	20/18639	0.5	1.44197740987158	0.115386029781216	0.354124608103598
GO:0016229	steroid dehydrogenase activity	16/6463	35/18639	0.457142857142857	1.3183793461683	0.117016191950739	0.358329583351375
GO:0003707	nuclear steroid receptor activity	12/6463	25/18639	0.48	1.38429831347671	0.118147841463507	0.359169113262342
GO:0004709	MAP kinase kinase kinase activity	12/6463	25/18639	0.48	1.38429831347671	0.118147841463507	0.359169113262342
GO:0015215	nucleotide transmembrane transporter activity	14/6463	30/18639	0.466666666666667	1.3458455825468	0.118332929913718	0.359169113262342
GO:0031624	ubiquitin conjugating enzyme binding	14/6463	30/18639	0.466666666666667	1.3458455825468	0.118332929913718	0.359169113262342
GO:0003689	DNA clamp loader activity	63/6463	160/18639	0.39375	1.13555721027387	0.12129841136939	0.367360903004438
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	21/6463	48/18639	0.4375	1.26173023363763	0.121693444771822	0.367740362935763
GO:0005126	cytokine receptor binding	105/6463	275/18639	0.381818181818182	1.10114638572011	0.121957435313239	0.367740362935763
GO:0015616	DNA translocase activity	60/6463	152/18639	0.394736842105263	1.13840321831967	0.123004369641337	0.368864853337943
GO:0140674	ATP-dependent histone chaperone activity	60/6463	152/18639	0.394736842105263	1.13840321831967	0.123004369641337	0.368864853337943
GO:0004535	poly(A)-specific ribonuclease activity	7/6463	13/18639	0.538461538461538	1.55289874909247	0.124039002723057	0.368864853337943
GO:0019855	calcium channel inhibitor activity	7/6463	13/18639	0.538461538461538	1.55289874909247	0.124039002723057	0.368864853337943
GO:0035325	Toll-like receptor binding	7/6463	13/18639	0.538461538461538	1.55289874909247	0.124039002723057	0.368864853337943
GO:0039706	co-receptor binding	7/6463	13/18639	0.538461538461538	1.55289874909247	0.124039002723057	0.368864853337943
GO:0140097	catalytic activity, acting on DNA	127/6463	336/18639	0.37797619047619	1.09006625627197	0.124204130586942	0.368864853337943
GO:0019001	guanyl nucleotide binding	150/6463	400/18639	0.375	1.08148305740368	0.125969452533262	0.372501943327971
GO:0032561	guanyl ribonucleotide binding	150/6463	400/18639	0.375	1.08148305740368	0.125969452533262	0.372501943327971
GO:0042162	telomeric DNA binding	17/6463	38/18639	0.447368421052632	1.29019031409562	0.129156876480658	0.381109584133506
GO:0140658	ATP-dependent chromatin remodeler activity	62/6463	158/18639	0.392405063291139	1.1316784735701	0.130264112887969	0.383555443503465
GO:0004706	JUN kinase kinase kinase activity	9/6463	18/18639	0.5	1.44197740987158	0.132407579234486	0.385745547960087
GO:0008409	5'-3' exonuclease activity	9/6463	18/18639	0.5	1.44197740987158	0.132407579234486	0.385745547960087
GO:0015172	acidic amino acid transmembrane transporter activity	9/6463	18/18639	0.5	1.44197740987158	0.132407579234486	0.385745547960087
GO:0034185	apolipoprotein binding	9/6463	18/18639	0.5	1.44197740987158	0.132407579234486	0.385745547960087
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	9/6463	18/18639	0.5	1.44197740987158	0.132407579234486	0.385745547960087
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	13/6463	28/18639	0.464285714285714	1.33897902345218	0.134368411932798	0.390632218656953
GO:0003887	DNA-directed DNA polymerase activity	11/6463	23/18639	0.478260869565217	1.37928273987716	0.134881615865123	0.391298666657135
GO:0051087	protein-folding chaperone binding	53/6463	134/18639	0.395522388059701	1.1406686973611	0.136110563207567	0.393243462888657
GO:0019888	protein phosphatase regulator activity	43/6463	107/18639	0.401869158878505	1.15897249765379	0.136122737153766	0.393243462888657
GO:0140375	immune receptor activity	61/6463	156/18639	0.391025641025641	1.12770028207905	0.139793416838713	0.402651645852261
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0004143	ATP-dependent diacylglycerol kinase activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0004954	prostanoid receptor activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0005225	volume-sensitive anion channel activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0008046	axon guidance receptor activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0019864	IgG binding	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0034713	type I transforming growth factor beta receptor binding	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0042608	T cell receptor binding	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0140537	transcription regulator activator activity	6/6463	11/18639	0.545454545454545	1.57306626531445	0.143178016304505	0.402651645852261
GO:0004540	RNA nuclease activity	48/6463	121/18639	0.396694214876033	1.14404819295596	0.144254333728723	0.404852284884278
GO:0033218	amide binding	94/6463	247/18639	0.380566801619433	1.0975374617646	0.14540508474339	0.406448899598858
GO:0055106	ubiquitin-protein transferase regulator activity	16/6463	36/18639	0.444444444444444	1.28175769766362	0.145413140422523	0.406448899598858
GO:0060590	ATPase regulator activity	21/6463	49/18639	0.428571428571429	1.23598063703278	0.146014850053449	0.407304581728042
GO:0016411	acylglycerol O-acyltransferase activity	14/6463	31/18639	0.451612903225806	1.30243120891626	0.149574708725123	0.416391815400443
GO:0016790	thiolester hydrolase activity	19/6463	44/18639	0.431818181818182	1.24534412670727	0.151947500447565	0.419555141717065
GO:0016722	oxidoreductase activity, acting on metal ions	8/6463	16/18639	0.5	1.44197740987158	0.152523712541365	0.419555141717065
GO:0030275	LRR domain binding	8/6463	16/18639	0.5	1.44197740987158	0.152523712541365	0.419555141717065
GO:0031435	mitogen-activated protein kinase kinase kinase binding	8/6463	16/18639	0.5	1.44197740987158	0.152523712541365	0.419555141717065
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/6463	16/18639	0.5	1.44197740987158	0.152523712541365	0.419555141717065
GO:0008198	ferrous iron binding	12/6463	26/18639	0.461538461538462	1.33105607065069	0.152842294007233	0.419555141717065
GO:0015216	purine nucleotide transmembrane transporter activity	12/6463	26/18639	0.461538461538462	1.33105607065069	0.152842294007233	0.419555141717065
GO:0008373	sialyltransferase activity	10/6463	21/18639	0.476190476190476	1.37331181892531	0.154391982145711	0.421291388904535
GO:0009931	calcium-dependent protein serine/threonine kinase activity	10/6463	21/18639	0.476190476190476	1.37331181892531	0.154391982145711	0.421291388904535
GO:0010314	phosphatidylinositol-5-phosphate binding	10/6463	21/18639	0.476190476190476	1.37331181892531	0.154391982145711	0.421291388904535
GO:0043178	alcohol binding	37/6463	92/18639	0.402173913043478	1.1598513948967	0.156243854259574	0.425502037884769
GO:0004714	transmembrane receptor protein tyrosine kinase activity	25/6463	60/18639	0.416666666666667	1.20164784155965	0.157649555494758	0.427894019985314
GO:0016798	hydrolase activity, acting on glycosyl bonds	51/6463	130/18639	0.392307692307692	1.13139766005308	0.157942274343719	0.427894019985314
GO:1902936	phosphatidylinositol bisphosphate binding	44/6463	111/18639	0.396396396396396	1.1431892979162	0.158053741779771	0.427894019985314
GO:0052866	phosphatidylinositol phosphate phosphatase activity	15/6463	34/18639	0.441176470588235	1.27233300871021	0.163834415042646	0.442674164566207
GO:0035250	UDP-galactosyltransferase activity	13/6463	29/18639	0.448275862068966	1.29280733298831	0.169410089874051	0.453513539986169
GO:0051861	glycolipid binding	13/6463	29/18639	0.448275862068966	1.29280733298831	0.169410089874051	0.453513539986169
GO:0099604	ligand-gated calcium channel activity	13/6463	29/18639	0.448275862068966	1.29280733298831	0.169410089874051	0.453513539986169
GO:0019894	kinesin binding	18/6463	42/18639	0.428571428571429	1.23598063703278	0.169820745016592	0.453513539986169
GO:0035198	miRNA binding	18/6463	42/18639	0.428571428571429	1.23598063703278	0.169820745016592	0.453513539986169
GO:0051879	Hsp90 protein binding	18/6463	42/18639	0.428571428571429	1.23598063703278	0.169820745016592	0.453513539986169
GO:0032813	tumor necrosis factor receptor superfamily binding	21/6463	50/18639	0.42	1.21126102429212	0.172869045183755	0.459861669006117
GO:0015295	solute:proton symporter activity	11/6463	24/18639	0.458333333333333	1.32181262571561	0.174200138767194	0.459861669006117
GO:0042625	ATPase-coupled ion transmembrane transporter activity	11/6463	24/18639	0.458333333333333	1.32181262571561	0.174200138767194	0.459861669006117
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	11/6463	24/18639	0.458333333333333	1.32181262571561	0.174200138767194	0.459861669006117
GO:0046961	proton-transporting ATPase activity, rotational mechanism	11/6463	24/18639	0.458333333333333	1.32181262571561	0.174200138767194	0.459861669006117
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	11/6463	24/18639	0.458333333333333	1.32181262571561	0.174200138767194	0.459861669006117
GO:0140713	histone chaperone activity	63/6463	164/18639	0.384146341463415	1.10786069295011	0.176296544183426	0.460731561357572
GO:0008174	mRNA methyltransferase activity	7/6463	14/18639	0.5	1.44197740987158	0.176535750650797	0.460731561357572
GO:0019992	diacylglycerol binding	7/6463	14/18639	0.5	1.44197740987158	0.176535750650797	0.460731561357572
GO:0032454	histone H3K9 demethylase activity	7/6463	14/18639	0.5	1.44197740987158	0.176535750650797	0.460731561357572
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	7/6463	14/18639	0.5	1.44197740987158	0.176535750650797	0.460731561357572
GO:0071933	Arp2/3 complex binding	7/6463	14/18639	0.5	1.44197740987158	0.176535750650797	0.460731561357572
GO:0042805	actinin binding	16/6463	37/18639	0.432432432432432	1.24711559772677	0.177223060999666	0.460917856655921
GO:0005346	purine ribonucleotide transmembrane transporter activity	9/6463	19/18639	0.473684210526316	1.3660838619836	0.177276098713816	0.460917856655921
GO:0008194	UDP-glycosyltransferase activity	56/6463	145/18639	0.386206896551724	1.11380324072839	0.179790976040644	0.466576205242952
GO:1901681	sulfur compound binding	103/6463	275/18639	0.374545454545455	1.08017216884925	0.180597914171941	0.467789334076945
GO:0141110	transporter inhibitor activity	19/6463	45/18639	0.422222222222222	1.21766981278044	0.181120111412191	0.46826175145591
GO:0004896	cytokine receptor activity	38/6463	96/18639	0.395833333333333	1.14156544948166	0.182041675794662	0.469762976114315
GO:0005246	calcium channel regulator activity	22/6463	53/18639	0.415094339622642	1.19711332140282	0.182686336391269	0.469905911437108
GO:0015026	coreceptor activity	25/6463	61/18639	0.409836065573771	1.18194869661605	0.182779077307903	0.469905911437108
GO:0008378	galactosyltransferase activity	14/6463	32/18639	0.4375	1.26173023363763	0.184732623020063	0.471410286151197
GO:0043425	bHLH transcription factor binding	14/6463	32/18639	0.4375	1.26173023363763	0.184732623020063	0.471410286151197
GO:0071813	lipoprotein particle binding	14/6463	32/18639	0.4375	1.26173023363763	0.184732623020063	0.471410286151197
GO:0071814	protein-lipid complex binding	14/6463	32/18639	0.4375	1.26173023363763	0.184732623020063	0.471410286151197
GO:0004683	calcium/calmodulin-dependent protein kinase activity	12/6463	27/18639	0.444444444444444	1.28175769766362	0.192136701957792	0.489398105910974
GO:0008168	methyltransferase activity	77/6463	204/18639	0.377450980392157	1.08855157411874	0.196398012339687	0.499129313277484
GO:0015297	antiporter activity	52/6463	135/18639	0.385185185185185	1.11085667130847	0.196681579905424	0.499129313277484
GO:0005154	epidermal growth factor receptor binding	15/6463	35/18639	0.428571428571429	1.23598063703278	0.198948082361575	0.499370346883996
GO:0043015	gamma-tubulin binding	15/6463	35/18639	0.428571428571429	1.23598063703278	0.198948082361575	0.499370346883996
GO:0061631	ubiquitin conjugating enzyme activity	15/6463	35/18639	0.428571428571429	1.23598063703278	0.198948082361575	0.499370346883996
GO:0008093	cytoskeletal anchor activity	10/6463	22/18639	0.454545454545455	1.31088855442871	0.198993333977254	0.499370346883996
GO:0061133	endopeptidase activator activity	10/6463	22/18639	0.454545454545455	1.31088855442871	0.198993333977254	0.499370346883996
GO:0008173	RNA methyltransferase activity	27/6463	67/18639	0.402985074626866	1.1621907482547	0.199313273429752	0.499370346883996
GO:0042054	histone methyltransferase activity	27/6463	67/18639	0.402985074626866	1.1621907482547	0.199313273429752	0.499370346883996
GO:0008375	acetylglucosaminyltransferase activity	18/6463	43/18639	0.418604651162791	1.20723690128783	0.201683314761226	0.502285832266377
GO:0005021	vascular endothelial growth factor receptor activity	21/6463	51/18639	0.411764705882353	1.18751080812953	0.202115544748716	0.502285832266377
GO:0005030	neurotrophin receptor activity	21/6463	51/18639	0.411764705882353	1.18751080812953	0.202115544748716	0.502285832266377
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	8/6463	17/18639	0.470588235294118	1.3571552092909	0.204315376912823	0.502285832266377
GO:0032183	SUMO binding	8/6463	17/18639	0.470588235294118	1.3571552092909	0.204315376912823	0.502285832266377
GO:0070402	NADPH binding	8/6463	17/18639	0.470588235294118	1.3571552092909	0.204315376912823	0.502285832266377
GO:0003995	acyl-CoA dehydrogenase activity	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0005049	nuclear export signal receptor activity	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0005078	MAP-kinase scaffold activity	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0005165	neurotrophin receptor binding	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0031543	peptidyl-proline dioxygenase activity	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0035251	UDP-glucosyltransferase activity	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:1990459	transferrin receptor binding	6/6463	12/18639	0.5	1.44197740987158	0.205579977792625	0.502285832266377
GO:0001618	virus receptor activity	32/6463	81/18639	0.395061728395062	1.139340175701	0.21105306232063	0.51474534491651
GO:0140098	catalytic activity, acting on RNA	142/6463	387/18639	0.366925064599483	1.05819530853625	0.214512281204373	0.522257815370363
GO:0016758	hexosyltransferase activity	74/6463	197/18639	0.375634517766497	1.08331297797459	0.216497723435219	0.526162015685594
GO:0015662	P-type ion transporter activity	11/6463	25/18639	0.44	1.26894012068699	0.218241229505804	0.527607744314031
GO:0120020	cholesterol transfer activity	11/6463	25/18639	0.44	1.26894012068699	0.218241229505804	0.527607744314031
GO:0140358	P-type transmembrane transporter activity	11/6463	25/18639	0.44	1.26894012068699	0.218241229505804	0.527607744314031
GO:0015932	nucleobase-containing compound transmembrane transporter activity	23/6463	57/18639	0.403508771929825	1.16370106761566	0.221225420166457	0.533885514867562
GO:0019239	deaminase activity	14/6463	33/18639	0.424242424242424	1.22349598413346	0.223423204957059	0.538246811942005
GO:0016877	ligase activity, forming carbon-sulfur bonds	17/6463	41/18639	0.414634146341463	1.19578614477155	0.224537975482603	0.539988359886608
GO:0008170	N-methyltransferase activity	38/6463	98/18639	0.387755102040816	1.11826819541061	0.225615823359626	0.541635199633387
GO:0015095	magnesium ion transmembrane transporter activity	9/6463	20/18639	0.45	1.29777966888442	0.227913427840488	0.544306245345221
GO:0016505	peptidase activator activity involved in apoptotic process	9/6463	20/18639	0.45	1.29777966888442	0.227913427840488	0.544306245345221
GO:0061608	nuclear import signal receptor activity	9/6463	20/18639	0.45	1.29777966888442	0.227913427840488	0.544306245345221
GO:0045499	chemorepellent activity	12/6463	28/18639	0.428571428571429	1.23598063703278	0.235462919476537	0.560863337746566
GO:0016248	channel inhibitor activity	18/6463	44/18639	0.409090909090909	1.17979969898584	0.236115801593761	0.560863337746566
GO:0140272	exogenous protein binding	32/6463	82/18639	0.390243902439024	1.1254457833144	0.236168676450108	0.560863337746566
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0004090	carbonyl reductase (NADPH) activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0004382	GDP phosphatase activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0004955	prostaglandin receptor activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0008641	ubiquitin-like modifier activating enzyme activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0015279	store-operated calcium channel activity	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0032356	oxidized DNA binding	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0043208	glycosphingolipid binding	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0043295	glutathione binding	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0050815	phosphoserine residue binding	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0051880	G-quadruplex DNA binding	5/6463	10/18639	0.5	1.44197740987158	0.24135846101866	0.560863337746566
GO:0008374	O-acyltransferase activity	22/6463	55/18639	0.4	1.15358192789726	0.243113022023754	0.563989468600561
GO:0008094	ATP-dependent activity, acting on DNA	78/6463	210/18639	0.371428571428571	1.07118321876174	0.246146494186316	0.570067006703771
GO:0000295	adenine nucleotide transmembrane transporter activity	10/6463	23/18639	0.434782608695652	1.25389339988833	0.248310040217354	0.573151148106389
GO:0004602	glutathione peroxidase activity	10/6463	23/18639	0.434782608695652	1.25389339988833	0.248310040217354	0.573151148106389
GO:0016776	phosphotransferase activity, phosphate group as acceptor	16/6463	39/18639	0.41025641025641	1.1831609516895	0.249918005509552	0.575898012695924
GO:0004519	endonuclease activity	48/6463	127/18639	0.377952755905512	1.08999867202891	0.256820944117093	0.590816319596739
GO:0005006	epidermal growth factor receptor activity	20/6463	50/18639	0.4	1.15358192789726	0.257249486036316	0.590816319596739
GO:0016853	isomerase activity	67/6463	180/18639	0.372222222222222	1.07347207179328	0.258672145692541	0.593095202602865
GO:0008308	voltage-gated monoatomic anion channel activity	8/6463	18/18639	0.444444444444444	1.28175769766362	0.261841615055493	0.598371053974245
GO:1990381	ubiquitin-specific protease binding	8/6463	18/18639	0.444444444444444	1.28175769766362	0.261841615055493	0.598371053974245
GO:0030165	PDZ domain binding	32/6463	83/18639	0.385542168674699	1.11188619556363	0.262556117401614	0.599010479767259
GO:0005003	ephrin receptor activity	21/6463	53/18639	0.39622641509434	1.14269907952087	0.266938516912385	0.605998807751675
GO:0005005	transmembrane-ephrin receptor activity	21/6463	53/18639	0.39622641509434	1.14269907952087	0.266938516912385	0.605998807751675
GO:0038064	collagen receptor activity	21/6463	53/18639	0.39622641509434	1.14269907952087	0.266938516912385	0.605998807751675
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	33/6463	86/18639	0.383720930232558	1.10663382618051	0.269113149681699	0.609930789903587
GO:0042605	peptide antigen binding	18/6463	45/18639	0.4	1.15358192789726	0.27277959504814	0.616234983224221
GO:0005035	death receptor activity	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0008035	high-density lipoprotein particle binding	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0043560	insulin receptor substrate binding	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0046975	histone H3K36 methyltransferase activity	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0097157	pre-mRNA intronic binding	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0140852	histone ubiquitin ligase activity	6/6463	13/18639	0.461538461538462	1.33105607065069	0.275472242137968	0.616234983224221
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	62/6463	167/18639	0.37125748502994	1.07068981331782	0.276895891549234	0.618415783719358
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/6463	21/18639	0.428571428571429	1.23598063703278	0.283054512111571	0.631147439627418
GO:0008013	beta-catenin binding	40/6463	106/18639	0.377358490566038	1.08828483763893	0.284818131073682	0.63405393314949
GO:0008276	protein methyltransferase activity	36/6463	95/18639	0.378947368421053	1.09286708958688	0.287612960219811	0.639242998682096
GO:0004532	RNA exonuclease activity	16/6463	40/18639	0.4	1.15358192789726	0.289986181256197	0.642647462283947
GO:0004527	exonuclease activity	32/6463	84/18639	0.380952380952381	1.09864945514025	0.290077446691303	0.642647462283947
GO:0004521	RNA endonuclease activity	28/6463	73/18639	0.383561643835616	1.10617445140833	0.292020943804085	0.645914703951893
GO:0005010	insulin-like growth factor receptor activity	20/6463	51/18639	0.392156862745098	1.13096267440908	0.292819770737994	0.646281759390458
GO:0015179	L-amino acid transmembrane transporter activity	24/6463	62/18639	0.387096774193548	1.11636960764251	0.293124890870128	0.646281759390458
GO:0008200	ion channel inhibitor activity	17/6463	43/18639	0.395348837209302	1.14016818454962	0.301017246678355	0.658409941586993
GO:0030215	semaphorin receptor binding	10/6463	24/18639	0.416666666666667	1.20164784155965	0.301245684110326	0.658409941586993
GO:0050699	WW domain binding	10/6463	24/18639	0.416666666666667	1.20164784155965	0.301245684110326	0.658409941586993
GO:0070840	dynein complex binding	10/6463	24/18639	0.416666666666667	1.20164784155965	0.301245684110326	0.658409941586993
GO:0004707	MAP kinase activity	7/6463	16/18639	0.4375	1.26173023363763	0.301922127285737	0.658409941586993
GO:0008142	oxysterol binding	7/6463	16/18639	0.4375	1.26173023363763	0.301922127285737	0.658409941586993
GO:0051287	NAD binding	21/6463	54/18639	0.388888888888889	1.12153798545567	0.301970307026836	0.658409941586993
GO:0016887	ATP hydrolysis activity	150/6463	417/18639	0.359712230215827	1.03739382005149	0.303517328768251	0.660737565628199
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	11/6463	27/18639	0.407407407407407	1.17494455619165	0.317119274874545	0.667017617468947
GO:0005004	GPI-linked ephrin receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0005008	hepatocyte growth factor receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0005009	insulin receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0005011	macrophage colony-stimulating factor receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0005018	platelet-derived growth factor alpha-receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0005020	stem cell factor receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0008288	boss receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0036332	placental growth factor receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0038062	protein tyrosine kinase collagen receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0060175	brain-derived neurotrophic factor receptor activity	19/6463	49/18639	0.387755102040816	1.11826819541061	0.320867414937322	0.667017617468947
GO:0005109	frizzled binding	15/6463	38/18639	0.394736842105263	1.13840321831967	0.32104494470478	0.667017617468947
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	15/6463	38/18639	0.394736842105263	1.13840321831967	0.32104494470478	0.667017617468947
GO:0042887	amide transmembrane transporter activity	15/6463	38/18639	0.394736842105263	1.13840321831967	0.32104494470478	0.667017617468947
GO:0048029	monosaccharide binding	28/6463	74/18639	0.378378378378378	1.09122614801092	0.322745168490385	0.667017617468947
GO:0000099	sulfur amino acid transmembrane transporter activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0002162	dystroglycan binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0008172	S-methyltransferase activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0008526	phosphatidylinositol transfer activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0015217	ADP transmembrane transporter activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0019107	myristoyltransferase activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0035252	UDP-xylosyltransferase activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0042285	xylosyltransferase activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0043522	leucine zipper domain binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0050998	nitric-oxide synthase binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:1900750	oligopeptide binding	5/6463	11/18639	0.454545454545455	1.31088855442871	0.323175498280456	0.667017617468947
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	8/6463	19/18639	0.421052631578947	1.21429676620764	0.323343808758532	0.667017617468947
GO:0003724	RNA helicase activity	29/6463	77/18639	0.376623376623377	1.08616480224093	0.329398269973497	0.678491503772017
GO:0033612	receptor serine/threonine kinase binding	12/6463	30/18639	0.4	1.15358192789726	0.331168014058204	0.681118691600307
GO:0061650	ubiquitin-like protein conjugating enzyme activity	16/6463	41/18639	0.390243902439024	1.1254457833144	0.331873032951297	0.681551474525913
GO:0016741	transferase activity, transferring one-carbon groups	78/6463	215/18639	0.362790697674419	1.04627198111612	0.333274627528489	0.682405962363124
GO:0016779	nucleotidyltransferase activity	50/6463	136/18639	0.367647058823529	1.06027750725851	0.333279544753543	0.682405962363124
GO:0042562	hormone binding	35/6463	94/18639	0.372340425531915	1.07381296479798	0.336183015222199	0.68732966613678
GO:0016279	protein-lysine N-methyltransferase activity	26/6463	69/18639	0.376811594202899	1.08670761323655	0.341103127254226	0.696355717564923
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	13/6463	33/18639	0.393939393939394	1.13610341383821	0.343748215438191	0.700717516085542
GO:0004065	arylsulfatase activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0005347	ATP transmembrane transporter activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0008191	metalloendopeptidase inhibitor activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0008331	high voltage-gated calcium channel activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0008474	palmitoyl-(protein) hydrolase activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0016530	metallochaperone activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0070742	C2H2 zinc finger domain binding	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0098599	palmitoyl hydrolase activity	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0098847	sequence-specific single stranded DNA binding	6/6463	14/18639	0.428571428571429	1.23598063703278	0.349674610753346	0.702359324913815
GO:0043495	protein-membrane adaptor activity	18/6463	47/18639	0.382978723404255	1.10449333522078	0.351179662456908	0.702359324913815
GO:0061749	forked DNA-dependent helicase activity	18/6463	47/18639	0.382978723404255	1.10449333522078	0.351179662456908	0.702359324913815
GO:1990518	single-stranded 3'-5' DNA helicase activity	18/6463	47/18639	0.382978723404255	1.10449333522078	0.351179662456908	0.702359324913815
GO:0047617	fatty acyl-CoA hydrolase activity	10/6463	25/18639	0.4	1.15358192789726	0.356581987180007	0.712130403382682
GO:0005007	fibroblast growth factor receptor activity	19/6463	50/18639	0.38	1.0959028315024	0.359859048779873	0.715563880546414
GO:0005017	platelet-derived growth factor receptor activity	19/6463	50/18639	0.38	1.0959028315024	0.359859048779873	0.715563880546414
GO:0005019	platelet-derived growth factor beta-receptor activity	19/6463	50/18639	0.38	1.0959028315024	0.359859048779873	0.715563880546414
GO:0004536	DNA nuclease activity	24/6463	64/18639	0.375	1.08148305740368	0.361063588482795	0.716924531598402
GO:0000217	DNA secondary structure binding	15/6463	39/18639	0.384615384615385	1.10921339220891	0.365499281701797	0.722663120126711
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	15/6463	39/18639	0.384615384615385	1.10921339220891	0.365499281701797	0.722663120126711
GO:0042626	ATPase-coupled transmembrane transporter activity	36/6463	98/18639	0.36734693877551	1.05941197459953	0.36970249761978	0.722663120126711
GO:0046625	sphingolipid binding	11/6463	28/18639	0.392857142857143	1.13298225061338	0.369955740132079	0.722663120126711
GO:0050698	proteoglycan sulfotransferase activity	11/6463	28/18639	0.392857142857143	1.13298225061338	0.369955740132079	0.722663120126711
GO:0051393	alpha-actinin binding	11/6463	28/18639	0.392857142857143	1.13298225061338	0.369955740132079	0.722663120126711
GO:0051959	dynein light intermediate chain binding	11/6463	28/18639	0.392857142857143	1.13298225061338	0.369955740132079	0.722663120126711
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	7/6463	17/18639	0.411764705882353	1.18751080812953	0.370246852546777	0.722663120126711
GO:0038191	neuropilin binding	7/6463	17/18639	0.411764705882353	1.18751080812953	0.370246852546777	0.722663120126711
GO:0045125	bioactive lipid receptor activity	7/6463	17/18639	0.411764705882353	1.18751080812953	0.370246852546777	0.722663120126711
GO:0051787	misfolded protein binding	7/6463	17/18639	0.411764705882353	1.18751080812953	0.370246852546777	0.722663120126711
GO:1990226	histone methyltransferase binding	7/6463	17/18639	0.411764705882353	1.18751080812953	0.370246852546777	0.722663120126711
GO:0015631	tubulin binding	137/6463	385/18639	0.355844155844156	1.02623846832419	0.370851479667443	0.722819432788877
GO:0016278	lysine N-methyltransferase activity	26/6463	70/18639	0.371428571428571	1.07118321876174	0.37441981534666	0.727871865302001
GO:0004520	DNA endonuclease activity	16/6463	42/18639	0.380952380952381	1.09864945514025	0.375028319567794	0.727871865302001
GO:0016859	cis-trans isomerase activity	16/6463	42/18639	0.380952380952381	1.09864945514025	0.375028319567794	0.727871865302001
GO:0005164	tumor necrosis factor receptor binding	12/6463	31/18639	0.387096774193548	1.11636960764251	0.381797962670018	0.736859373332331
GO:0016878	acid-thiol ligase activity	12/6463	31/18639	0.387096774193548	1.11636960764251	0.381797962670018	0.736859373332331
GO:0070273	phosphatidylinositol-4-phosphate binding	12/6463	31/18639	0.387096774193548	1.11636960764251	0.381797962670018	0.736859373332331
GO:0072349	modified amino acid transmembrane transporter activity	12/6463	31/18639	0.387096774193548	1.11636960764251	0.381797962670018	0.736859373332331
GO:0001786	phosphatidylserine binding	22/6463	59/18639	0.372881355932203	1.07537298363304	0.382871070502928	0.737896972242007
GO:0017022	myosin binding	28/6463	76/18639	0.368421052631579	1.06250967043169	0.386618643491084	0.740606220008286
GO:0001614	purinergic nucleotide receptor activity	8/6463	20/18639	0.4	1.15358192789726	0.386964062703894	0.740606220008286
GO:0001972	retinoic acid binding	8/6463	20/18639	0.4	1.15358192789726	0.386964062703894	0.740606220008286
GO:0016502	nucleotide receptor activity	8/6463	20/18639	0.4	1.15358192789726	0.386964062703894	0.740606220008286
GO:0030742	GTP-dependent protein binding	8/6463	20/18639	0.4	1.15358192789726	0.386964062703894	0.740606220008286
GO:0009378	four-way junction helicase activity	18/6463	48/18639	0.375	1.08148305740368	0.392020464024968	0.745855933552749
GO:0036121	double-stranded DNA helicase activity	18/6463	48/18639	0.375	1.08148305740368	0.392020464024968	0.745855933552749
GO:0043138	3'-5' DNA helicase activity	18/6463	48/18639	0.375	1.08148305740368	0.392020464024968	0.745855933552749
GO:0008186	ATP-dependent activity, acting on RNA	29/6463	79/18639	0.367088607594937	1.05866695914622	0.39234267473279	0.745855933552749
GO:0008376	acetylgalactosaminyltransferase activity	13/6463	34/18639	0.382352941176471	1.10268860754885	0.392413317725503	0.745855933552749
GO:0008237	metallopeptidase activity	66/6463	184/18639	0.358695652173913	1.03446205490787	0.392970879071613	0.745886875152455
GO:0120013	lipid transfer activity	24/6463	65/18639	0.369230769230769	1.06484485652055	0.396203883228857	0.750988928596101
GO:0008171	O-methyltransferase activity	9/6463	23/18639	0.391304347826087	1.12850405989949	0.400998287306224	0.75414439181537
GO:0016849	phosphorus-oxygen lyase activity	9/6463	23/18639	0.391304347826087	1.12850405989949	0.400998287306224	0.75414439181537
GO:0017134	fibroblast growth factor binding	9/6463	23/18639	0.391304347826087	1.12850405989949	0.400998287306224	0.75414439181537
GO:0004857	enzyme inhibitor activity	147/6463	416/18639	0.353365384615385	1.01908980409193	0.405336147759844	0.75414439181537
GO:0004126	cytidine deaminase activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0004875	complement receptor activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0008179	adenylate cyclase binding	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0016208	AMP binding	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0016801	hydrolase activity, acting on ether bonds	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0016803	ether hydrolase activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0017166	vinculin binding	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0043047	single-stranded telomeric DNA binding	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0070008	serine-type exopeptidase activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0070679	inositol 1,4,5 trisphosphate binding	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/6463	12/18639	0.416666666666667	1.20164784155965	0.407172298628908	0.75414439181537
GO:0015036	disulfide oxidoreductase activity	15/6463	40/18639	0.375	1.08148305740368	0.410807141969157	0.7588367850315
GO:0030331	nuclear estrogen receptor binding	15/6463	40/18639	0.375	1.08148305740368	0.410807141969157	0.7588367850315
GO:0016289	acyl-CoA hydrolase activity	10/6463	26/18639	0.384615384615385	1.10921339220891	0.413070448622873	0.759961386117916
GO:0030247	polysaccharide binding	10/6463	26/18639	0.384615384615385	1.10921339220891	0.413070448622873	0.759961386117916
GO:0030507	spectrin binding	10/6463	26/18639	0.384615384615385	1.10921339220891	0.413070448622873	0.759961386117916
GO:0003684	damaged DNA binding	27/6463	74/18639	0.364864864864865	1.05225378558196	0.413916764971999	0.760503069508554
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	22/6463	60/18639	0.366666666666667	1.05745010057249	0.419954146680814	0.77056832773124
GO:0000049	tRNA binding	29/6463	80/18639	0.3625	1.04543362215689	0.42449720939319	0.774822673663621
GO:0000774	adenyl-nucleotide exchange factor activity	6/6463	15/18639	0.4	1.15358192789726	0.425084137365528	0.774822673663621
GO:0015929	hexosaminidase activity	6/6463	15/18639	0.4	1.15358192789726	0.425084137365528	0.774822673663621
GO:0047372	monoacylglycerol lipase activity	6/6463	15/18639	0.4	1.15358192789726	0.425084137365528	0.774822673663621
GO:0140776	protein-containing complex destabilizing activity	6/6463	15/18639	0.4	1.15358192789726	0.425084137365528	0.774822673663621
GO:0030276	clathrin binding	17/6463	46/18639	0.369565217391304	1.06580938990508	0.426368516117107	0.776137140303003
GO:0008235	metalloexopeptidase activity	24/6463	66/18639	0.363636363636364	1.04871084354296	0.431734586654954	0.784868417428135
GO:0031369	translation initiation factor binding	12/6463	32/18639	0.375	1.08148305740368	0.433068268031927	0.786255696110666
GO:0050660	flavin adenine dinucleotide binding	31/6463	86/18639	0.36046511627907	1.0395651094423	0.434272230693839	0.787404123547513
GO:0000900	mRNA regulatory element binding translation repressor activity	7/6463	18/18639	0.388888888888889	1.12153798545567	0.439232003677594	0.790158878678491
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	7/6463	18/18639	0.388888888888889	1.12153798545567	0.439232003677594	0.790158878678491
GO:0017075	syntaxin-1 binding	7/6463	18/18639	0.388888888888889	1.12153798545567	0.439232003677594	0.790158878678491
GO:0031690	adrenergic receptor binding	7/6463	18/18639	0.388888888888889	1.12153798545567	0.439232003677594	0.790158878678491
GO:0032393	MHC class I receptor activity	7/6463	18/18639	0.388888888888889	1.12153798545567	0.439232003677594	0.790158878678491
GO:0050811	GABA receptor binding	7/6463	18/18639	0.388888888888889	1.12153798545567	0.439232003677594	0.790158878678491
GO:0000175	3'-5'-RNA exonuclease activity	13/6463	35/18639	0.371428571428571	1.07118321876174	0.441549246049457	0.792258933666865
GO:0034061	DNA polymerase activity	13/6463	35/18639	0.371428571428571	1.07118321876174	0.441549246049457	0.792258933666865
GO:0043531	ADP binding	14/6463	38/18639	0.368421052631579	1.06250967043169	0.449265618062126	0.805055944979986
GO:0019200	carbohydrate kinase activity	8/6463	21/18639	0.380952380952381	1.09864945514025	0.450908401529939	0.805903731917324
GO:0035613	RNA stem-loop binding	8/6463	21/18639	0.380952380952381	1.09864945514025	0.450908401529939	0.805903731917324
GO:0061980	regulatory RNA binding	21/6463	58/18639	0.362068965517241	1.04419053818287	0.451757286239263	0.806375052380446
GO:0008017	microtubule binding	97/6463	276/18639	0.351449275362319	1.0135638315764	0.45702921337966	0.814729956063612
GO:0015085	calcium ion transmembrane transporter activity	52/6463	147/18639	0.353741496598639	1.0201744940588	0.459947236372249	0.81887246992372
GO:0048027	mRNA 5'-UTR binding	9/6463	24/18639	0.375	1.08148305740368	0.460849849223763	0.819066070903992
GO:0051117	ATPase binding	30/6463	84/18639	0.357142857142857	1.02998386419398	0.461244754006892	0.819066070903992
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	46/6463	130/18639	0.353846153846154	1.02047632083219	0.465151515407084	0.823237817225512
GO:0004222	metalloendopeptidase activity	39/6463	110/18639	0.354545454545455	1.02249307245439	0.467325868878949	0.823237817225512
GO:0016500	protein-hormone receptor activity	24/6463	67/18639	0.358208955223881	1.03305844289307	0.467363388472256	0.823237817225512
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	24/6463	67/18639	0.358208955223881	1.03305844289307	0.467363388472256	0.823237817225512
GO:0001671	ATPase activator activity	10/6463	27/18639	0.37037037037037	1.06813141471969	0.469512315533654	0.823237817225512
GO:0016405	CoA-ligase activity	10/6463	27/18639	0.37037037037037	1.06813141471969	0.469512315533654	0.823237817225512
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	10/6463	27/18639	0.37037037037037	1.06813141471969	0.469512315533654	0.823237817225512
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	11/6463	30/18639	0.366666666666667	1.05745010057249	0.477196023003839	0.823237817225512
GO:0001094	TFIID-class transcription factor complex binding	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0005031	tumor necrosis factor receptor activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0015643	toxic substance binding	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0016427	tRNA (cytidine) methyltransferase activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0016783	sulfurtransferase activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0019911	structural constituent of myelin sheath	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0050308	sugar-phosphatase activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0071723	lipopeptide binding	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0098505	G-rich strand telomeric DNA binding	4/6463	10/18639	0.4	1.15358192789726	0.477334554399989	0.823237817225512
GO:0031490	chromatin DNA binding	45/6463	128/18639	0.3515625	1.01389036631595	0.487588375506506	0.830182132288273
GO:0008417	fucosyltransferase activity	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0009982	pseudouridine synthase activity	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0030955	potassium ion binding	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0032396	inhibitory MHC class I receptor activity	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0045159	myosin II binding	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0061459	L-arginine transmembrane transporter activity	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0071714	icosanoid transmembrane transporter activity	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0089720	caspase binding	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:1901338	catecholamine binding	5/6463	13/18639	0.384615384615385	1.10921339220891	0.489484833935745	0.830182132288273
GO:0004190	aspartic-type endopeptidase activity	13/6463	36/18639	0.361111111111111	1.04142812935169	0.490397863340097	0.830182132288273
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	13/6463	36/18639	0.361111111111111	1.04142812935169	0.490397863340097	0.830182132288273
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	13/6463	36/18639	0.361111111111111	1.04142812935169	0.490397863340097	0.830182132288273
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	13/6463	36/18639	0.361111111111111	1.04142812935169	0.490397863340097	0.830182132288273
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	6/6463	16/18639	0.375	1.08148305740368	0.498981343413403	0.83742985022002
GO:0004708	MAP kinase kinase activity	6/6463	16/18639	0.375	1.08148305740368	0.498981343413403	0.83742985022002
GO:0005324	long-chain fatty acid transmembrane transporter activity	6/6463	16/18639	0.375	1.08148305740368	0.498981343413403	0.83742985022002
GO:0017070	U6 snRNA binding	6/6463	16/18639	0.375	1.08148305740368	0.498981343413403	0.83742985022002
GO:0019841	retinol binding	6/6463	16/18639	0.375	1.08148305740368	0.498981343413403	0.83742985022002
GO:0043177	organic acid binding	66/6463	189/18639	0.349206349206349	1.00709533387856	0.499069101316238	0.83742985022002
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	32/6463	91/18639	0.351648351648352	1.014137958591	0.500262553718735	0.83742985022002
GO:0072341	modified amino acid binding	32/6463	91/18639	0.351648351648352	1.014137958591	0.500262553718735	0.83742985022002
GO:0042056	chemoattractant activity	15/6463	42/18639	0.357142857142857	1.02998386419398	0.501522568490217	0.83742985022002
GO:0051539	4 iron, 4 sulfur cluster binding	16/6463	45/18639	0.355555555555556	1.0254061581309	0.506506119902386	0.83742985022002
GO:0003756	protein disulfide isomerase activity	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0015245	fatty acid transmembrane transporter activity	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0022821	solute:potassium antiporter activity	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0030506	ankyrin binding	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0043395	heparan sulfate proteoglycan binding	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0046527	glucosyltransferase activity	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0070003	threonine-type peptidase activity	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0120227	acyl-CoA binding	7/6463	19/18639	0.368421052631579	1.06250967043169	0.506833450713713	0.83742985022002
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	63/6463	181/18639	0.348066298342541	1.00380747869513	0.51319300482536	0.843503426506265
GO:0031683	G-protein beta/gamma-subunit complex binding	8/6463	22/18639	0.363636363636364	1.04871084354296	0.513569938199388	0.843503426506265
GO:0033691	sialic acid binding	8/6463	22/18639	0.363636363636364	1.04871084354296	0.513569938199388	0.843503426506265
GO:0034062	5'-3' RNA polymerase activity	8/6463	22/18639	0.363636363636364	1.04871084354296	0.513569938199388	0.843503426506265
GO:0097747	RNA polymerase activity	8/6463	22/18639	0.363636363636364	1.04871084354296	0.513569938199388	0.843503426506265
GO:0017069	snRNA binding	19/6463	54/18639	0.351851851851852	1.0147248439837	0.519736171088308	0.852614813999629
GO:0016866	intramolecular transferase activity	10/6463	28/18639	0.357142857142857	1.02998386419398	0.524821524090084	0.8589121855061
GO:0097718	disordered domain specific binding	10/6463	28/18639	0.357142857142857	1.02998386419398	0.524821524090084	0.8589121855061
GO:0030246	carbohydrate binding	97/6463	280/18639	0.346428571428571	0.999084348268164	0.527201805524413	0.860296509222161
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	21/6463	60/18639	0.35	1.0093841869101	0.52744928164778	0.860296509222161
GO:0003727	single-stranded RNA binding	31/6463	89/18639	0.348314606741573	1.0045235888993	0.527540312258873	0.860296509222161
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	12/6463	34/18639	0.352941176470588	1.01786640696817	0.534123741918211	0.870002974424698
GO:0070001	aspartic-type peptidase activity	13/6463	37/18639	0.351351351351351	1.013281423153	0.538265727066363	0.875714488662868
GO:0015101	organic cation transmembrane transporter activity	28/6463	81/18639	0.345679012345679	0.996922653738374	0.549875968743958	0.893548449208931
GO:0035254	glutamate receptor binding	17/6463	49/18639	0.346938775510204	1.00055575378844	0.552530030212676	0.896803747506557
GO:0017116	single-stranded DNA helicase activity	20/6463	58/18639	0.344827586206897	0.994467179221777	0.561543795737672	0.900525620910723
GO:0001851	complement component C3b binding	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0004016	adenylate cyclase activity	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0019203	carbohydrate phosphatase activity	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0019215	intermediate filament binding	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0032050	clathrin heavy chain binding	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0032404	mismatch repair complex binding	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0047676	arachidonate-CoA ligase activity	4/6463	11/18639	0.363636363636364	1.04871084354296	0.56542544361115	0.900525620910723
GO:0004705	JUN kinase activity	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0005313	L-glutamate transmembrane transporter activity	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0015386	potassium:proton antiporter activity	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0019763	immunoglobulin receptor activity	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0030983	mismatched DNA binding	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0032036	myosin heavy chain binding	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0042043	neurexin family protein binding	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0044548	S100 protein binding	5/6463	14/18639	0.357142857142857	1.02998386419398	0.567157180148189	0.900525620910723
GO:0004029	aldehyde dehydrogenase (NAD+) activity	6/6463	17/18639	0.352941176470588	1.01786640696817	0.569200156613381	0.900525620910723
GO:0017110	nucleoside diphosphate phosphatase activity	6/6463	17/18639	0.352941176470588	1.01786640696817	0.569200156613381	0.900525620910723
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	6/6463	17/18639	0.352941176470588	1.01786640696817	0.569200156613381	0.900525620910723
GO:1901567	fatty acid derivative binding	6/6463	17/18639	0.352941176470588	1.01786640696817	0.569200156613381	0.900525620910723
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/6463	20/18639	0.35	1.0093841869101	0.571378505795923	0.902935299296768
GO:0140103	catalytic activity, acting on a glycoprotein	8/6463	23/18639	0.347826086956522	1.00311471991066	0.573608152009075	0.905420427798974
GO:0004435	phosphatidylinositol phospholipase C activity	9/6463	26/18639	0.346153846153846	0.998292052988015	0.575845854388347	0.905839711583495
GO:0005112	Notch binding	9/6463	26/18639	0.346153846153846	0.998292052988015	0.575845854388347	0.905839711583495
GO:0051139	metal cation:proton antiporter activity	9/6463	26/18639	0.346153846153846	0.998292052988015	0.575845854388347	0.905839711583495
GO:0004629	phospholipase C activity	10/6463	29/18639	0.344827586206897	0.994467179221777	0.578068421124985	0.908299069909041
GO:0031406	carboxylic acid binding	64/6463	187/18639	0.342245989304813	0.987021970393379	0.579121488386557	0.908639453528864
GO:0051059	NF-kappaB binding	11/6463	32/18639	0.34375	0.991359469286709	0.580263221411756	0.908639453528864
GO:0070717	poly-purine tract binding	11/6463	32/18639	0.34375	0.991359469286709	0.580263221411756	0.908639453528864
GO:0017080	sodium channel regulator activity	14/6463	41/18639	0.341463414634146	0.984765060400101	0.586628710647281	0.916524221396772
GO:0140828	metal cation:monoatomic cation antiporter activity	14/6463	41/18639	0.341463414634146	0.984765060400101	0.586628710647281	0.916524221396772
GO:0141108	transporter regulator activity	58/6463	170/18639	0.341176470588235	0.983937526735899	0.589557414690857	0.920056758147226
GO:0070888	E-box binding	20/6463	59/18639	0.338983050847458	0.977611803302764	0.598322160521431	0.932678661989289
GO:0043021	ribonucleoprotein complex binding	60/6463	177/18639	0.338983050847458	0.977611803302764	0.614080950107922	0.956162202540922
GO:0140101	catalytic activity, acting on a tRNA	47/6463	139/18639	0.338129496402878	0.975150190848404	0.616118124060308	0.958251439001246
GO:0099106	ion channel regulator activity	54/6463	160/18639	0.3375	0.973334751663314	0.626482439956594	0.96323211470039
GO:0030296	protein tyrosine kinase activator activity	11/6463	33/18639	0.333333333333333	0.961318273247718	0.628340683074889	0.96323211470039
GO:0008106	alcohol dehydrogenase (NADP+) activity	10/6463	30/18639	0.333333333333333	0.961318273247718	0.628504620185558	0.96323211470039
GO:0051721	protein phosphatase 2A binding	10/6463	30/18639	0.333333333333333	0.961318273247718	0.628504620185558	0.96323211470039
GO:0070566	adenylyltransferase activity	10/6463	30/18639	0.333333333333333	0.961318273247718	0.628504620185558	0.96323211470039
GO:0004364	glutathione transferase activity	9/6463	27/18639	0.333333333333333	0.961318273247718	0.629012623815693	0.96323211470039
GO:0008266	poly(U) RNA binding	9/6463	27/18639	0.333333333333333	0.961318273247718	0.629012623815693	0.96323211470039
GO:0035255	ionotropic glutamate receptor binding	9/6463	27/18639	0.333333333333333	0.961318273247718	0.629012623815693	0.96323211470039
GO:0008307	structural constituent of muscle	14/6463	42/18639	0.333333333333333	0.961318273247718	0.629181781725813	0.96323211470039
GO:0008009	chemokine activity	15/6463	45/18639	0.333333333333333	0.961318273247718	0.629754970587535	0.96323211470039
GO:0140303	intramembrane lipid transporter activity	15/6463	45/18639	0.333333333333333	0.961318273247718	0.629754970587535	0.96323211470039
GO:0004622	lysophospholipase activity	8/6463	24/18639	0.333333333333333	0.961318273247718	0.62998730340173	0.96323211470039
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	8/6463	24/18639	0.333333333333333	0.961318273247718	0.62998730340173	0.96323211470039
GO:0030552	cAMP binding	8/6463	24/18639	0.333333333333333	0.961318273247718	0.62998730340173	0.96323211470039
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	41/6463	122/18639	0.336065573770492	0.969197931225158	0.631321822149181	0.96323211470039
GO:0015174	basic amino acid transmembrane transporter activity	7/6463	21/18639	0.333333333333333	0.961318273247718	0.631613557928915	0.96323211470039
GO:0000400	four-way junction DNA binding	6/6463	18/18639	0.333333333333333	0.961318273247718	0.634184233081276	0.96323211470039
GO:0005262	calcium channel activity	44/6463	131/18639	0.33587786259542	0.96865658067709	0.635339989404281	0.96323211470039
GO:0004467	long-chain fatty acid-CoA ligase activity	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0005402	carbohydrate:monoatomic cation symporter activity	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0008252	nucleotidase activity	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0010181	FMN binding	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0015556	C4-dicarboxylate transmembrane transporter activity	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0017081	chloride channel regulator activity	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0033130	acetylcholine receptor binding	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0048531	beta-1,3-galactosyltransferase activity	5/6463	15/18639	0.333333333333333	0.961318273247718	0.638193701539518	0.96323211470039
GO:0004000	adenosine deaminase activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0008504	monoamine transmembrane transporter activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0015132	prostaglandin transmembrane transporter activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0015166	polyol transmembrane transporter activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0015368	calcium:monoatomic cation antiporter activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0035197	siRNA binding	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0045295	gamma-catenin binding	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/6463	12/18639	0.333333333333333	0.961318273247718	0.644552016102272	0.963332622764566
GO:0008408	3'-5' exonuclease activity	19/6463	58/18639	0.327586206896552	0.944743820260688	0.667592646769177	0.995669022232249
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	20/6463	61/18639	0.327868852459016	0.945558957292837	0.667632929276196	0.995669022232249
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	14/6463	43/18639	0.325581395348837	0.93896203433498	0.669439030695157	0.996720216850906
GO:0071949	FAD binding	13/6463	40/18639	0.325	0.937285316416525	0.670422457842285	0.996720216850906
GO:0016247	channel regulator activity	56/6463	168/18639	0.333333333333333	0.961318273247718	0.670614955449012	0.996720216850906
GO:0015035	protein-disulfide reductase activity	11/6463	34/18639	0.323529411764706	0.933044206387491	0.673400959280256	0.996720216850906
GO:0016831	carboxy-lyase activity	11/6463	34/18639	0.323529411764706	0.933044206387491	0.673400959280256	0.996720216850906
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	11/6463	34/18639	0.323529411764706	0.933044206387491	0.673400959280256	0.996720216850906
GO:0090482	vitamin transmembrane transporter activity	11/6463	34/18639	0.323529411764706	0.933044206387491	0.673400959280256	0.996720216850906
GO:0005537	D-mannose binding	8/6463	25/18639	0.32	0.922865542317809	0.681981083062133	1
GO:0015645	fatty acid ligase activity	8/6463	25/18639	0.32	0.922865542317809	0.681981083062133	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	8/6463	25/18639	0.32	0.922865542317809	0.681981083062133	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	8/6463	25/18639	0.32	0.922865542317809	0.681981083062133	1
GO:0120515	fatty acid-CoA ligase activity	8/6463	25/18639	0.32	0.922865542317809	0.681981083062133	1
GO:0140517	protein-RNA adaptor activity	7/6463	22/18639	0.318181818181818	0.917621988100094	0.68670058046936	1
GO:0140784	metal ion sensor activity	7/6463	22/18639	0.318181818181818	0.917621988100094	0.68670058046936	1
GO:0015291	secondary active transmembrane transporter activity	96/6463	287/18639	0.334494773519164	0.964667814269487	0.690485630338546	1
GO:0005520	insulin-like growth factor binding	6/6463	19/18639	0.315789473684211	0.910722574655733	0.69296151725092	1
GO:0008574	plus-end-directed microtubule motor activity	6/6463	19/18639	0.315789473684211	0.910722574655733	0.69296151725092	1
GO:0016918	retinal binding	6/6463	19/18639	0.315789473684211	0.910722574655733	0.69296151725092	1
GO:0022840	leak channel activity	6/6463	19/18639	0.315789473684211	0.910722574655733	0.69296151725092	1
GO:0022842	narrow pore channel activity	6/6463	19/18639	0.315789473684211	0.910722574655733	0.69296151725092	1
GO:0050145	nucleoside monophosphate kinase activity	6/6463	19/18639	0.315789473684211	0.910722574655733	0.69296151725092	1
GO:0004175	endopeptidase activity	136/6463	405/18639	0.335802469135802	0.968439149345849	0.697347666113773	1
GO:0016209	antioxidant activity	28/6463	86/18639	0.325581395348837	0.93896203433498	0.697813678911917	1
GO:0003678	DNA helicase activity	24/6463	74/18639	0.324324324324324	0.935336698295077	0.698099528985564	1
GO:0140299	molecular sensor activity	23/6463	71/18639	0.323943661971831	0.934238885268909	0.698360762135025	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	19/6463	59/18639	0.322033898305085	0.928731213137626	0.700496127736857	1
GO:0000062	fatty-acyl-CoA binding	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0005149	interleukin-1 receptor binding	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0015385	sodium:proton antiporter activity	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0015562	efflux transmembrane transporter activity	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0022841	potassium ion leak channel activity	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0043023	ribosomal large subunit binding	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0140328	floppase activity	5/6463	16/18639	0.3125	0.901235881169735	0.701472046142297	1
GO:0008146	sulfotransferase activity	17/6463	53/18639	0.320754716981132	0.925042111993087	0.702457774469135	1
GO:0016860	intramolecular oxidoreductase activity	17/6463	53/18639	0.320754716981132	0.925042111993087	0.702457774469135	1
GO:0017046	peptide hormone binding	17/6463	53/18639	0.320754716981132	0.925042111993087	0.702457774469135	1
GO:0140359	ABC-type transporter activity	15/6463	47/18639	0.319148936170213	0.920411112683985	0.705289583938761	1
GO:0019205	nucleobase-containing compound kinase activity	14/6463	44/18639	0.318181818181818	0.917621988100094	0.707130302185293	1
GO:0005172	vascular endothelial growth factor receptor binding	4/6463	13/18639	0.307692307692308	0.887370713767124	0.713470763731838	1
GO:0008253	5'-nucleotidase activity	4/6463	13/18639	0.307692307692308	0.887370713767124	0.713470763731838	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	4/6463	13/18639	0.307692307692308	0.887370713767124	0.713470763731838	1
GO:0019104	DNA N-glycosylase activity	4/6463	13/18639	0.307692307692308	0.887370713767124	0.713470763731838	1
GO:0031994	insulin-like growth factor I binding	4/6463	13/18639	0.307692307692308	0.887370713767124	0.713470763731838	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	4/6463	13/18639	0.307692307692308	0.887370713767124	0.713470763731838	1
GO:0042910	xenobiotic transmembrane transporter activity	10/6463	32/18639	0.3125	0.901235881169735	0.718892902051134	1
GO:0003785	actin monomer binding	9/6463	29/18639	0.310344827586207	0.895020461299599	0.723500349311732	1
GO:0043236	laminin binding	9/6463	29/18639	0.310344827586207	0.895020461299599	0.723500349311732	1
GO:0106222	lncRNA binding	9/6463	29/18639	0.310344827586207	0.895020461299599	0.723500349311732	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	43/6463	132/18639	0.325757575757576	0.939470130673906	0.723755242588268	1
GO:0004529	DNA exonuclease activity	8/6463	26/18639	0.307692307692308	0.887370713767124	0.729152295806038	1
GO:0008143	poly(A) binding	8/6463	26/18639	0.307692307692308	0.887370713767124	0.729152295806038	1
GO:0019865	immunoglobulin binding	8/6463	26/18639	0.307692307692308	0.887370713767124	0.729152295806038	1
GO:1901682	sulfur compound transmembrane transporter activity	20/6463	63/18639	0.317460317460317	0.915541212616874	0.730034159680515	1
GO:0000182	rDNA binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0004935	adrenergic receptor activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0005345	purine nucleobase transmembrane transporter activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0005528	FK506 binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0015203	polyamine transmembrane transporter activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0016868	intramolecular phosphotransferase activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0030957	Tat protein binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0031419	cobalamin binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0031996	thioesterase binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0032052	bile acid binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0035256	G protein-coupled glutamate receptor binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0043121	neurotrophin binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0097177	mitochondrial ribosome binding	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0141109	transporter activator activity	3/6463	10/18639	0.3	0.865186445922946	0.731366315253661	1
GO:0005212	structural constituent of eye lens	7/6463	23/18639	0.304347826086957	0.877725379921829	0.736178517920735	1
GO:0016830	carbon-carbon lyase activity	16/6463	51/18639	0.313725490196078	0.904770139527264	0.736923033583548	1
GO:0043022	ribosome binding	36/6463	112/18639	0.321428571428571	0.926985477774585	0.744826065719961	1
GO:0000339	RNA cap binding	6/6463	20/18639	0.3	0.865186445922946	0.745068522160205	1
GO:0005326	neurotransmitter transmembrane transporter activity	6/6463	20/18639	0.3	0.865186445922946	0.745068522160205	1
GO:0042288	MHC class I protein binding	6/6463	20/18639	0.3	0.865186445922946	0.745068522160205	1
GO:0043024	ribosomal small subunit binding	6/6463	20/18639	0.3	0.865186445922946	0.745068522160205	1
GO:0140939	histone H4 methyltransferase activity	6/6463	20/18639	0.3	0.865186445922946	0.745068522160205	1
GO:0004033	aldo-keto reductase (NADPH) activity	11/6463	36/18639	0.305555555555556	0.881208417143741	0.753230552284318	1
GO:0004549	tRNA-specific ribonuclease activity	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0004550	nucleoside diphosphate kinase activity	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0004659	prenyltransferase activity	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0031489	myosin V binding	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0036041	long-chain fatty acid binding	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0045236	CXCR chemokine receptor binding	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0070403	NAD+ binding	5/6463	17/18639	0.294117647058824	0.84822200580681	0.756585333446012	1
GO:0019956	chemokine binding	10/6463	33/18639	0.303030303030303	0.873925702952471	0.758263432040807	1
GO:0008187	poly-pyrimidine tract binding	9/6463	30/18639	0.3	0.865186445922946	0.764212804651521	1
GO:0031210	phosphatidylcholine binding	9/6463	30/18639	0.3	0.865186445922946	0.764212804651521	1
GO:0098632	cell-cell adhesion mediator activity	17/6463	55/18639	0.309090909090909	0.89140421701152	0.764888072397443	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	8/6463	27/18639	0.296296296296296	0.854505131775749	0.771316368223026	1
GO:0008494	translation activator activity	4/6463	14/18639	0.285714285714286	0.823987091355187	0.771996197165299	1
GO:0008559	ABC-type xenobiotic transporter activity	4/6463	14/18639	0.285714285714286	0.823987091355187	0.771996197165299	1
GO:1901474	azole transmembrane transporter activity	4/6463	14/18639	0.285714285714286	0.823987091355187	0.771996197165299	1
GO:1901612	cardiolipin binding	4/6463	14/18639	0.285714285714286	0.823987091355187	0.771996197165299	1
GO:0004180	carboxypeptidase activity	14/6463	46/18639	0.304347826086957	0.877725379921829	0.774170383276476	1
GO:0005245	voltage-gated calcium channel activity	13/6463	43/18639	0.302325581395349	0.871893317596767	0.778106764746408	1
GO:0008083	growth factor activity	52/6463	162/18639	0.320987654320988	0.925713892757062	0.779731477177304	1
GO:0005315	phosphate transmembrane transporter activity	7/6463	24/18639	0.291666666666667	0.841153489091753	0.779904312134443	1
GO:0070300	phosphatidic acid binding	7/6463	24/18639	0.291666666666667	0.841153489091753	0.779904312134443	1
GO:0003774	cytoskeletal motor activity	49/6463	153/18639	0.320261437908497	0.923619517434082	0.780202810588679	1
GO:0030551	cyclic nucleotide binding	11/6463	37/18639	0.297297297297297	0.857391973437154	0.787716566401781	1
GO:0005248	voltage-gated sodium channel activity	6/6463	21/18639	0.285714285714286	0.823987091355187	0.790450507852722	1
GO:0009975	cyclase activity	6/6463	21/18639	0.285714285714286	0.823987091355187	0.790450507852722	1
GO:0061891	calcium ion sensor activity	6/6463	21/18639	0.285714285714286	0.823987091355187	0.790450507852722	1
GO:0008199	ferric iron binding	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0008271	secondary active sulfate transmembrane transporter activity	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0010854	adenylate cyclase regulator activity	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0015205	nucleobase transmembrane transporter activity	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0034056	estrogen response element binding	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0045294	alpha-catenin binding	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0070697	activin receptor binding	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0070990	snRNP binding	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	3/6463	11/18639	0.272727272727273	0.786533132657224	0.793594142119603	1
GO:0004864	protein phosphatase inhibitor activity	16/6463	53/18639	0.30188679245283	0.870627870111141	0.795799733854817	1
GO:0005504	fatty acid binding	14/6463	47/18639	0.297872340425532	0.859050371838386	0.803392540571264	1
GO:0003746	translation elongation factor activity	5/6463	18/18639	0.277777777777778	0.801098561039765	0.803662679740141	1
GO:0008525	phosphatidylcholine transporter activity	5/6463	18/18639	0.277777777777778	0.801098561039765	0.803662679740141	1
GO:0017128	phospholipid scramblase activity	5/6463	18/18639	0.277777777777778	0.801098561039765	0.803662679740141	1
GO:0098641	cadherin binding involved in cell-cell adhesion	5/6463	18/18639	0.277777777777778	0.801098561039765	0.803662679740141	1
GO:1901611	phosphatidylglycerol binding	5/6463	18/18639	0.277777777777778	0.801098561039765	0.803662679740141	1
GO:0051015	actin filament binding	67/6463	209/18639	0.320574162679426	0.924521401544456	0.808059340851691	1
GO:0005242	inward rectifier potassium channel activity	8/6463	28/18639	0.285714285714286	0.823987091355187	0.808496394459001	1
GO:0005507	copper ion binding	19/6463	63/18639	0.301587301587302	0.86976415198603	0.811625535105699	1
GO:0001530	lipopolysaccharide binding	12/6463	41/18639	0.292682926829268	0.844084337485801	0.812903031103239	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	12/6463	41/18639	0.292682926829268	0.844084337485801	0.812903031103239	1
GO:0004601	peroxidase activity	17/6463	57/18639	0.298245614035088	0.860126876063747	0.817880256409636	1
GO:0008483	transaminase activity	7/6463	25/18639	0.28	0.807507349528083	0.817985567884786	1
GO:0015271	outward rectifier potassium channel activity	7/6463	25/18639	0.28	0.807507349528083	0.817985567884786	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	7/6463	25/18639	0.28	0.807507349528083	0.817985567884786	1
GO:0005501	retinoid binding	11/6463	38/18639	0.289473684210526	0.834829026767755	0.818583792240709	1
GO:0019840	isoprenoid binding	11/6463	38/18639	0.289473684210526	0.834829026767755	0.818583792240709	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	4/6463	15/18639	0.266666666666667	0.769054618598174	0.820651650120128	1
GO:0045504	dynein heavy chain binding	4/6463	15/18639	0.266666666666667	0.769054618598174	0.820651650120128	1
GO:0050700	CARD domain binding	4/6463	15/18639	0.266666666666667	0.769054618598174	0.820651650120128	1
GO:0001664	G protein-coupled receptor binding	96/6463	297/18639	0.323232323232323	0.932187416482635	0.820902558790901	1
GO:0033293	monocarboxylic acid binding	24/6463	79/18639	0.30379746835443	0.876138173086528	0.821310056702893	1
GO:0098631	cell adhesion mediator activity	23/6463	76/18639	0.302631578947368	0.872775800711744	0.823495858555948	1
GO:0005272	sodium channel activity	15/6463	51/18639	0.294117647058824	0.84822200580681	0.825417813562327	1
GO:0016597	amino acid binding	15/6463	51/18639	0.294117647058824	0.84822200580681	0.825417813562327	1
GO:0016782	transferase activity, transferring sulphur-containing groups	21/6463	70/18639	0.3	0.865186445922946	0.828396805086634	1
GO:0015377	chloride:monoatomic cation symporter activity	6/6463	22/18639	0.272727272727273	0.786533132657224	0.829356730621482	1
GO:0045296	cadherin binding	108/6463	334/18639	0.323353293413174	0.932536289018744	0.832491487971572	1
GO:0052689	carboxylic ester hydrolase activity	28/6463	92/18639	0.304347826086957	0.877725379921829	0.832903387117114	1
GO:0022804	active transmembrane transporter activity	149/6463	457/18639	0.326039387308534	0.940282862454551	0.839255364390014	1
GO:0005506	iron ion binding	48/6463	154/18639	0.311688311688312	0.898895008751113	0.842085053336088	1
GO:0031420	alkali metal ion binding	5/6463	19/18639	0.263157894736842	0.758935478879777	0.843198809200577	1
GO:0042834	peptidoglycan binding	5/6463	19/18639	0.263157894736842	0.758935478879777	0.843198809200577	1
GO:0046624	sphingolipid transporter activity	5/6463	19/18639	0.263157894736842	0.758935478879777	0.843198809200577	1
GO:0000340	RNA 7-methylguanosine cap binding	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0004300	enoyl-CoA hydratase activity	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0005527	macrolide binding	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0016273	arginine N-methyltransferase activity	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0016274	protein-arginine N-methyltransferase activity	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0016840	carbon-nitrogen lyase activity	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0042301	phosphate ion binding	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0140900	chloride:bicarbonate antiporter activity	3/6463	12/18639	0.25	0.720988704935788	0.843274850792047	1
GO:0031491	nucleosome binding	22/6463	74/18639	0.297297297297297	0.857391973437154	0.845803431609417	1
GO:0016298	lipase activity	40/6463	130/18639	0.307692307692308	0.887370713767124	0.848988061145155	1
GO:0005227	calcium-activated cation channel activity	7/6463	26/18639	0.269230769230769	0.776449374546234	0.850713615492746	1
GO:0120014	phospholipid transfer activity	7/6463	26/18639	0.269230769230769	0.776449374546234	0.850713615492746	1
GO:0003697	single-stranded DNA binding	37/6463	121/18639	0.305785123966942	0.88187048207022	0.852388380192975	1
GO:0051082	unfolded protein binding	37/6463	121/18639	0.305785123966942	0.88187048207022	0.852388380192975	1
GO:0045505	dynein intermediate chain binding	10/6463	36/18639	0.277777777777778	0.801098561039765	0.852648392145956	1
GO:0004620	phospholipase activity	33/6463	109/18639	0.302752293577982	0.873123936252514	0.857820469855902	1
GO:0003688	DNA replication origin binding	4/6463	16/18639	0.25	0.720988704935788	0.860378184779405	1
GO:0008296	3'-5'-DNA exonuclease activity	4/6463	16/18639	0.25	0.720988704935788	0.860378184779405	1
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/6463	16/18639	0.25	0.720988704935788	0.860378184779405	1
GO:0022858	alanine transmembrane transporter activity	4/6463	16/18639	0.25	0.720988704935788	0.860378184779405	1
GO:0055102	lipase inhibitor activity	4/6463	16/18639	0.25	0.720988704935788	0.860378184779405	1
GO:0140327	flippase activity	4/6463	16/18639	0.25	0.720988704935788	0.860378184779405	1
GO:0015459	potassium channel regulator activity	17/6463	59/18639	0.288135593220339	0.830970032807349	0.861588793119854	1
GO:0031681	G-protein beta-subunit binding	6/6463	23/18639	0.260869565217391	0.752336039932996	0.86224315863351	1
GO:0019212	phosphatase inhibitor activity	16/6463	56/18639	0.285714285714286	0.823987091355187	0.865526277302247	1
GO:0030170	pyridoxal phosphate binding	16/6463	56/18639	0.285714285714286	0.823987091355187	0.865526277302247	1
GO:0016769	transferase activity, transferring nitrogenous groups	8/6463	30/18639	0.266666666666667	0.769054618598174	0.86875330771225	1
GO:0022839	monoatomic ion-gated channel activity	8/6463	30/18639	0.266666666666667	0.769054618598174	0.86875330771225	1
GO:0048019	receptor antagonist activity	8/6463	30/18639	0.266666666666667	0.769054618598174	0.86875330771225	1
GO:0005319	lipid transporter activity	55/6463	178/18639	0.308988764044944	0.891109635313896	0.873977603894412	1
GO:0140664	ATP-dependent DNA damage sensor activity	5/6463	20/18639	0.25	0.720988704935788	0.875908904880701	1
GO:0015399	primary active transmembrane transporter activity	51/6463	166/18639	0.307228915662651	0.886034312089764	0.876900543498213	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/6463	13/18639	0.230769230769231	0.665528035325343	0.882216076910109	1
GO:0031432	titin binding	3/6463	13/18639	0.230769230769231	0.665528035325343	0.882216076910109	1
GO:0071837	HMG box domain binding	3/6463	13/18639	0.230769230769231	0.665528035325343	0.882216076910109	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/6463	13/18639	0.230769230769231	0.665528035325343	0.882216076910109	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/6463	13/18639	0.230769230769231	0.665528035325343	0.882216076910109	1
GO:0140666	annealing activity	3/6463	13/18639	0.230769230769231	0.665528035325343	0.882216076910109	1
GO:0070279	vitamin B6 binding	16/6463	57/18639	0.280701754385965	0.809531177471762	0.884119846431071	1
GO:0004806	triacylglycerol lipase activity	6/6463	24/18639	0.25	0.720988704935788	0.889689440799866	1
GO:0005540	hyaluronic acid binding	6/6463	24/18639	0.25	0.720988704935788	0.889689440799866	1
GO:0140612	DNA damage sensor activity	6/6463	24/18639	0.25	0.720988704935788	0.889689440799866	1
GO:0016018	cyclosporin A binding	4/6463	17/18639	0.235294117647059	0.678577604645448	0.892314446728141	1
GO:0048038	quinone binding	4/6463	17/18639	0.235294117647059	0.678577604645448	0.892314446728141	1
GO:0005452	solute:inorganic anion antiporter activity	8/6463	31/18639	0.258064516129032	0.744246405095007	0.892502176757851	1
GO:0008327	methyl-CpG binding	8/6463	31/18639	0.258064516129032	0.744246405095007	0.892502176757851	1
GO:0022853	active monoatomic ion transmembrane transporter activity	35/6463	118/18639	0.296610169491525	0.855410327889918	0.894570311381112	1
GO:0000146	microfilament motor activity	10/6463	38/18639	0.263157894736842	0.758935478879777	0.897452010872416	1
GO:0036122	BMP binding	5/6463	21/18639	0.238095238095238	0.686655909462655	0.902614653951944	1
GO:0003777	microtubule motor activity	19/6463	68/18639	0.279411764705882	0.805810905516469	0.904415780425277	1
GO:0005548	phospholipid transporter activity	19/6463	68/18639	0.279411764705882	0.805810905516469	0.904415780425277	1
GO:0008519	ammonium channel activity	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0033204	ribonuclease P RNA binding	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0035374	chondroitin sulfate binding	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0047429	nucleoside triphosphate diphosphatase activity	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0070739	protein-glutamic acid ligase activity	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0070740	tubulin-glutamic acid ligase activity	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0140135	mechanosensitive monoatomic cation channel activity	2/6463	10/18639	0.2	0.576790963948631	0.910787795935541	1
GO:0031404	chloride ion binding	3/6463	14/18639	0.214285714285714	0.61799031851639	0.912276044113239	1
GO:0015106	bicarbonate transmembrane transporter activity	8/6463	32/18639	0.25	0.720988704935788	0.912536615733128	1
GO:0015280	ligand-gated sodium channel activity	4/6463	18/18639	0.222222222222222	0.640878848831812	0.917643523010427	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/6463	18/18639	0.222222222222222	0.640878848831812	0.917643523010427	1
GO:0070628	proteasome binding	4/6463	18/18639	0.222222222222222	0.640878848831812	0.917643523010427	1
GO:0061134	peptidase regulator activity	69/6463	226/18639	0.305309734513274	0.88049948036406	0.918401949468668	1
GO:0170055	lipid transmembrane transporter activity	15/6463	56/18639	0.267857142857143	0.772487898145487	0.919112551359464	1
GO:0004181	metallocarboxypeptidase activity	7/6463	29/18639	0.241379310344828	0.696127025455244	0.921235144730015	1
GO:0008970	phospholipase A1 activity	5/6463	22/18639	0.227272727272727	0.655444277214353	0.924161101990316	1
GO:0016881	acid-amino acid ligase activity	5/6463	22/18639	0.227272727272727	0.655444277214353	0.924161101990316	1
GO:0070034	telomerase RNA binding	5/6463	22/18639	0.227272727272727	0.655444277214353	0.924161101990316	1
GO:0008135	translation factor activity, RNA binding	23/6463	83/18639	0.27710843373494	0.799168203061356	0.928840274009342	1
GO:0005200	structural constituent of cytoskeleton	32/6463	112/18639	0.285714285714286	0.823987091355187	0.929785428588652	1
GO:0019842	vitamin binding	44/6463	150/18639	0.293333333333333	0.845960080457992	0.93024870020742	1
GO:0015144	carbohydrate transmembrane transporter activity	10/6463	40/18639	0.25	0.720988704935788	0.930292199807063	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	10/6463	40/18639	0.25	0.720988704935788	0.930292199807063	1
GO:0050997	quaternary ammonium group binding	10/6463	40/18639	0.25	0.720988704935788	0.930292199807063	1
GO:0001637	G protein-coupled chemoattractant receptor activity	6/6463	26/18639	0.230769230769231	0.665528035325343	0.930818515167666	1
GO:0004950	chemokine receptor activity	6/6463	26/18639	0.230769230769231	0.665528035325343	0.930818515167666	1
GO:0048306	calcium-dependent protein binding	22/6463	80/18639	0.275	0.793087575429367	0.931319748120719	1
GO:0004129	cytochrome-c oxidase activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0008242	omega peptidase activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0015116	sulfate transmembrane transporter activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0015250	water channel activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0016846	carbon-sulfur lyase activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0030553	cGMP binding	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0031386	protein tag activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0034483	heparan sulfate sulfotransferase activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0141047	molecular tag activity	3/6463	15/18639	0.2	0.576790963948631	0.935182142611517	1
GO:0005536	D-glucose binding	2/6463	11/18639	0.181818181818182	0.524355421771482	0.936830830116861	1
GO:0015173	aromatic amino acid transmembrane transporter activity	2/6463	11/18639	0.181818181818182	0.524355421771482	0.936830830116861	1
GO:0019206	nucleoside kinase activity	2/6463	11/18639	0.181818181818182	0.524355421771482	0.936830830116861	1
GO:0050786	RAGE receptor binding	2/6463	11/18639	0.181818181818182	0.524355421771482	0.936830830116861	1
GO:1990948	ubiquitin ligase inhibitor activity	2/6463	11/18639	0.181818181818182	0.524355421771482	0.936830830116861	1
GO:0005229	intracellularly calcium-gated chloride channel activity	4/6463	19/18639	0.210526315789474	0.607148383103822	0.937495446693054	1
GO:0008301	DNA binding, bending	4/6463	19/18639	0.210526315789474	0.607148383103822	0.937495446693054	1
GO:0008381	mechanosensitive monoatomic ion channel activity	4/6463	19/18639	0.210526315789474	0.607148383103822	0.937495446693054	1
GO:0042577	lipid phosphatase activity	4/6463	19/18639	0.210526315789474	0.607148383103822	0.937495446693054	1
GO:0141147	intracellularly calcium-gated channel activity	4/6463	19/18639	0.210526315789474	0.607148383103822	0.937495446693054	1
GO:0030547	signaling receptor inhibitor activity	11/6463	44/18639	0.25	0.720988704935788	0.93765607399436	1
GO:0180051	translation factor activity	23/6463	84/18639	0.273809523809524	0.789654295882054	0.93836928386754	1
GO:0016836	hydro-lyase activity	16/6463	61/18639	0.262295081967213	0.75644716583427	0.938890907727393	1
GO:0003743	translation initiation factor activity	13/6463	51/18639	0.254901960784314	0.735125738365902	0.939781045480845	1
GO:0005283	amino acid:sodium symporter activity	5/6463	23/18639	0.217391304347826	0.626946699944164	0.941360530700539	1
GO:0042287	MHC protein binding	10/6463	41/18639	0.24390243902439	0.703403614571501	0.942998348803468	1
GO:0051427	hormone receptor binding	8/6463	34/18639	0.235294117647059	0.678577604645448	0.943166641729691	1
GO:0005104	fibroblast growth factor receptor binding	6/6463	27/18639	0.222222222222222	0.640878848831812	0.945765904633528	1
GO:0042379	chemokine receptor binding	19/6463	72/18639	0.263888888888889	0.761043632987777	0.948318333359769	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	7/6463	31/18639	0.225806451612903	0.651215604458131	0.950247040520546	1
GO:0047499	calcium-independent phospholipase A2 activity	7/6463	31/18639	0.225806451612903	0.651215604458131	0.950247040520546	1
GO:0016835	carbon-oxygen lyase activity	21/6463	79/18639	0.265822784810127	0.766620901450712	0.951303916719887	1
GO:0036002	pre-mRNA binding	15/6463	59/18639	0.254237288135593	0.733208852477073	0.95173904068329	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/6463	16/18639	0.1875	0.540741528701841	0.952444594418927	1
GO:0010851	cyclase regulator activity	4/6463	20/18639	0.2	0.576790963948631	0.952892082146142	1
GO:0016408	C-acyltransferase activity	4/6463	20/18639	0.2	0.576790963948631	0.952892082146142	1
GO:0051536	iron-sulfur cluster binding	20/6463	76/18639	0.263157894736842	0.758935478879777	0.953662860064607	1
GO:0005343	organic acid:sodium symporter activity	8/6463	35/18639	0.228571428571429	0.659189673084149	0.95458279815432	1
GO:0019957	C-C chemokine binding	5/6463	24/18639	0.208333333333333	0.600823920779824	0.954958185937559	1
GO:0003720	telomerase activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0004032	aldose reductase (NADPH) activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0004526	ribonuclease P activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0004859	phospholipase inhibitor activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0010853	cyclase activator activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0015269	calcium-activated potassium channel activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0097371	MDM2/MDM4 family protein binding	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:1990817	poly(A) RNA polymerase activity	2/6463	12/18639	0.166666666666667	0.480659136623859	0.955542025981823	1
GO:0051119	sugar transmembrane transporter activity	6/6463	28/18639	0.214285714285714	0.61799031851639	0.957746222834527	1
GO:0051537	2 iron, 2 sulfur cluster binding	6/6463	28/18639	0.214285714285714	0.61799031851639	0.957746222834527	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	18/6463	70/18639	0.257142857142857	0.741588382219668	0.958593727740576	1
GO:0051540	metal cluster binding	20/6463	77/18639	0.25974025974026	0.74907917395926	0.960596626300447	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	8/6463	36/18639	0.222222222222222	0.640878848831812	0.96390168686124	1
GO:0001846	opsonin binding	4/6463	21/18639	0.19047619047619	0.549324727570124	0.964722065250659	1
GO:0015125	bile acid transmembrane transporter activity	4/6463	21/18639	0.19047619047619	0.549324727570124	0.964722065250659	1
GO:0008569	minus-end-directed microtubule motor activity	3/6463	17/18639	0.176470588235294	0.508933203484086	0.965329626066953	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/6463	17/18639	0.176470588235294	0.508933203484086	0.965329626066953	1
GO:0030548	acetylcholine receptor regulator activity	3/6463	17/18639	0.176470588235294	0.508933203484086	0.965329626066953	1
GO:0001848	complement binding	5/6463	25/18639	0.2	0.576790963948631	0.965614540149739	1
GO:0005251	delayed rectifier potassium channel activity	5/6463	25/18639	0.2	0.576790963948631	0.965614540149739	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	23/6463	88/18639	0.261363636363636	0.753760918796506	0.966431367804816	1
GO:0044183	protein folding chaperone	19/6463	75/18639	0.253333333333333	0.730601887668266	0.968643249105097	1
GO:0002161	aminoacyl-tRNA editing activity	2/6463	13/18639	0.153846153846154	0.443685356883562	0.968874016722135	1
GO:0003964	RNA-directed DNA polymerase activity	2/6463	13/18639	0.153846153846154	0.443685356883562	0.968874016722135	1
GO:0004465	lipoprotein lipase activity	2/6463	13/18639	0.153846153846154	0.443685356883562	0.968874016722135	1
GO:0005542	folic acid binding	2/6463	13/18639	0.153846153846154	0.443685356883562	0.968874016722135	1
GO:0140333	glycerophospholipid flippase activity	2/6463	13/18639	0.153846153846154	0.443685356883562	0.968874016722135	1
GO:0015171	amino acid transmembrane transporter activity	27/6463	102/18639	0.264705882352941	0.763399805226129	0.970042254190184	1
GO:0008514	organic anion transmembrane transporter activity	79/6463	269/18639	0.29368029739777	0.8469607091439	0.972932724228396	1
GO:0005243	gap junction channel activity	4/6463	22/18639	0.181818181818182	0.524355421771482	0.973735612641846	1
GO:0015145	monosaccharide transmembrane transporter activity	5/6463	26/18639	0.192307692307692	0.554606696104453	0.973899308002613	1
GO:0016829	lyase activity	57/6463	200/18639	0.285	0.821927123626799	0.973972212817473	1
GO:0005372	water transmembrane transporter activity	3/6463	18/18639	0.166666666666667	0.480659136623859	0.974866846678258	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/6463	18/18639	0.166666666666667	0.480659136623859	0.974866846678258	1
GO:0099602	neurotransmitter receptor regulator activity	3/6463	18/18639	0.166666666666667	0.480659136623859	0.974866846678258	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	12/6463	52/18639	0.230769230769231	0.665528035325343	0.974903850015217	1
GO:0008195	phosphatidate phosphatase activity	2/6463	14/18639	0.142857142857143	0.411993545677593	0.978307012156951	1
GO:1990825	sequence-specific mRNA binding	2/6463	14/18639	0.142857142857143	0.411993545677593	0.978307012156951	1
GO:0005544	calcium-dependent phospholipid binding	12/6463	53/18639	0.226415094339623	0.652970902583355	0.979668002678217	1
GO:0008395	steroid hydroxylase activity	5/6463	27/18639	0.185185185185185	0.534065707359843	0.980293263313769	1
GO:0016493	C-C chemokine receptor activity	4/6463	23/18639	0.173913043478261	0.501557359955331	0.980551419366332	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/6463	46/18639	0.217391304347826	0.626946699944164	0.980640273138773	1
GO:0004623	phospholipase A2 activity	7/6463	35/18639	0.2	0.576790963948631	0.981436671373579	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/6463	19/18639	0.157894736842105	0.455361287327866	0.981873984175484	1
GO:0034987	immunoglobulin receptor binding	3/6463	19/18639	0.157894736842105	0.455361287327866	0.981873984175484	1
GO:0015293	symporter activity	39/6463	146/18639	0.267123287671233	0.770371492945089	0.984373299797113	1
GO:0004089	carbonate dehydratase activity	2/6463	15/18639	0.133333333333333	0.384527309299087	0.984941607471634	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/6463	15/18639	0.133333333333333	0.384527309299087	0.984941607471634	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/6463	15/18639	0.133333333333333	0.384527309299087	0.984941607471634	1
GO:0140161	monocarboxylate:sodium symporter activity	2/6463	15/18639	0.133333333333333	0.384527309299087	0.984941607471634	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	13/6463	58/18639	0.224137931034483	0.646403666494155	0.984954896458445	1
GO:0047498	calcium-dependent phospholipase A2 activity	6/6463	32/18639	0.1875	0.540741528701841	0.985261503053925	1
GO:0015149	hexose transmembrane transporter activity	4/6463	24/18639	0.166666666666667	0.480659136623859	0.985670066052086	1
GO:0055056	D-glucose transmembrane transporter activity	4/6463	24/18639	0.166666666666667	0.480659136623859	0.985670066052086	1
GO:0003796	lysozyme activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0004983	neuropeptide Y receptor activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0005337	nucleoside transmembrane transporter activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0019531	oxalate transmembrane transporter activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0140940	histone H2A methyltransferase activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/6463	10/18639	0.1	0.288395481974315	0.985866050928392	1
GO:0015079	potassium ion transmembrane transporter activity	43/6463	160/18639	0.26875	0.775062857805972	0.986190014179237	1
GO:0140662	ATP-dependent protein folding chaperone	8/6463	40/18639	0.2	0.576790963948631	0.986284699709691	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/6463	20/18639	0.15	0.432593222961473	0.98698843747478	1
GO:0003954	NADH dehydrogenase activity	9/6463	44/18639	0.204545454545455	0.589899849492918	0.987019156426906	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/6463	48/18639	0.208333333333333	0.600823920779824	0.987813523896404	1
GO:0061135	endopeptidase regulator activity	50/6463	184/18639	0.271739130434783	0.783683374930205	0.988188306149509	1
GO:0046873	metal ion transmembrane transporter activity	134/6463	450/18639	0.297777777777778	0.858777657434628	0.98875623766818	1
GO:0042923	neuropeptide binding	6/6463	33/18639	0.181818181818182	0.524355421771482	0.988810165799173	1
GO:0005416	amino acid:monoatomic cation symporter activity	5/6463	29/18639	0.172413793103448	0.497233589610889	0.988928948425124	1
GO:0022829	wide pore channel activity	7/6463	37/18639	0.189189189189189	0.545613074005461	0.988985698237805	1
GO:0008227	G protein-coupled amine receptor activity	8/6463	41/18639	0.195121951219512	0.562722891657201	0.989351719596284	1
GO:0015378	sodium:chloride symporter activity	2/6463	16/18639	0.125	0.360494352467894	0.989584037907734	1
GO:1904047	S-adenosyl-L-methionine binding	3/6463	21/18639	0.142857142857143	0.411993545677593	0.990699499512133	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0008503	benzodiazepine receptor activity	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0016594	glycine binding	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0031731	CCR6 chemokine receptor binding	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0034511	U3 snoRNA binding	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/6463	11/18639	0.0909090909090909	0.262177710885741	0.990769573009545	1
GO:0015020	glucuronosyltransferase activity	6/6463	34/18639	0.176470588235294	0.508933203484086	0.991541080599769	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/6463	34/18639	0.176470588235294	0.508933203484086	0.991541080599769	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	15/6463	68/18639	0.220588235294118	0.636166504355107	0.991695146849122	1
GO:0048020	CCR chemokine receptor binding	10/6463	50/18639	0.2	0.576790963948631	0.992448370344652	1
GO:0009881	photoreceptor activity	2/6463	17/18639	0.117647058823529	0.339288802322724	0.992817959486505	1
GO:0070492	oligosaccharide binding	2/6463	17/18639	0.117647058823529	0.339288802322724	0.992817959486505	1
GO:0046943	carboxylic acid transmembrane transporter activity	50/6463	188/18639	0.265957446808511	0.767009260569988	0.993083269030137	1
GO:0022832	voltage-gated channel activity	46/6463	175/18639	0.262857142857143	0.758068124046772	0.993247488675504	1
GO:0015078	proton transmembrane transporter activity	49/6463	185/18639	0.264864864864865	0.763858303607646	0.993351677939025	1
GO:0005125	cytokine activity	64/6463	234/18639	0.273504273504274	0.788773967792999	0.993405287554135	1
GO:0005342	organic acid transmembrane transporter activity	50/6463	189/18639	0.264550264550265	0.762951010514062	0.993974517564689	1
GO:0046982	protein heterodimerization activity	106/6463	369/18639	0.287262872628726	0.828453146050879	0.994002601015268	1
GO:0005244	voltage-gated monoatomic ion channel activity	45/6463	173/18639	0.260115606936416	0.750161658314693	0.994407097659828	1
GO:0022843	voltage-gated monoatomic cation channel activity	36/6463	143/18639	0.251748251748252	0.726030583991283	0.994489269345531	1
GO:0015294	solute:monoatomic cation symporter activity	28/6463	116/18639	0.241379310344828	0.696127025455244	0.994707141860004	1
GO:0015373	monoatomic anion:sodium symporter activity	2/6463	18/18639	0.111111111111111	0.320439424415906	0.995061848587536	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/6463	23/18639	0.130434782608696	0.376168019966498	0.995301996255187	1
GO:0140102	catalytic activity, acting on a rRNA	3/6463	23/18639	0.130434782608696	0.376168019966498	0.995301996255187	1
GO:0004993	G protein-coupled serotonin receptor activity	1/6463	13/18639	0.0769230769230769	0.221842678441781	0.996063582331681	1
GO:0004812	aminoacyl-tRNA ligase activity	7/6463	41/18639	0.170731707317073	0.492382530200051	0.996308110923088	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	7/6463	41/18639	0.170731707317073	0.492382530200051	0.996308110923088	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	7/6463	41/18639	0.170731707317073	0.492382530200051	0.996308110923088	1
GO:0005254	chloride channel activity	18/6463	83/18639	0.216867469879518	0.625435985004539	0.996542471688976	1
GO:0099094	ligand-gated monoatomic cation channel activity	33/6463	136/18639	0.242647058823529	0.699783154790618	0.996746140484293	1
GO:0009055	electron transfer activity	27/6463	116/18639	0.232758620689655	0.671265345974699	0.997165442788741	1
GO:0031492	nucleosomal DNA binding	7/6463	42/18639	0.166666666666667	0.480659136623859	0.99721642905934	1
GO:0005344	oxygen carrier activity	1/6463	14/18639	0.0714285714285714	0.205996772838797	0.997429472345122	1
GO:0008392	arachidonate epoxygenase activity	1/6463	14/18639	0.0714285714285714	0.205996772838797	0.997429472345122	1
GO:0015926	glucosidase activity	1/6463	14/18639	0.0714285714285714	0.205996772838797	0.997429472345122	1
GO:0061783	peptidoglycan muralytic activity	1/6463	14/18639	0.0714285714285714	0.205996772838797	0.997429472345122	1
GO:0005253	monoatomic anion channel activity	23/6463	103/18639	0.223300970873786	0.643989911204782	0.997716124763466	1
GO:0030414	peptidase inhibitor activity	42/6463	169/18639	0.248520710059172	0.716722499581139	0.997782901180759	1
GO:0046906	tetrapyrrole binding	37/6463	152/18639	0.243421052631579	0.702015317963794	0.997792153035663	1
GO:0015108	chloride transmembrane transporter activity	28/6463	121/18639	0.231404958677686	0.667361445890978	0.997852360319012	1
GO:0098918	structural constituent of synapse	4/6463	30/18639	0.133333333333333	0.384527309299087	0.997897107149092	1
GO:0020037	heme binding	34/6463	142/18639	0.23943661971831	0.690524393459628	0.997905057415298	1
GO:0051428	peptide hormone receptor binding	2/6463	21/18639	0.0952380952380952	0.274662363785062	0.998417882174529	1
GO:0070182	DNA polymerase binding	2/6463	21/18639	0.0952380952380952	0.274662363785062	0.998417882174529	1
GO:0004866	endopeptidase inhibitor activity	39/6463	161/18639	0.242236024844721	0.698597751366354	0.998460925472958	1
GO:0005249	voltage-gated potassium channel activity	21/6463	98/18639	0.214285714285714	0.61799031851639	0.99854213918819	1
GO:0019843	rRNA binding	12/6463	65/18639	0.184615384615385	0.532422428260275	0.998767375660253	1
GO:0005267	potassium channel activity	28/6463	124/18639	0.225806451612903	0.651215604458131	0.998781384944967	1
GO:0008391	arachidonate monooxygenase activity	1/6463	16/18639	0.0625	0.180247176233947	0.998903957678927	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/6463	16/18639	0.0625	0.180247176233947	0.998903957678927	1
GO:0030515	snoRNA binding	4/6463	32/18639	0.125	0.360494352467894	0.998920262783712	1
GO:0008649	rRNA methyltransferase activity	2/6463	22/18639	0.0909090909090909	0.262177710885741	0.998921869595448	1
GO:0015081	sodium ion transmembrane transporter activity	39/6463	164/18639	0.23780487804878	0.685818524207213	0.999077982408211	1
GO:0008527	taste receptor activity	3/6463	28/18639	0.107142857142857	0.308995159258195	0.999192819275962	1
GO:0015103	inorganic anion transmembrane transporter activity	39/6463	165/18639	0.236363636363636	0.681662048302927	0.999225344035887	1
GO:0099186	structural constituent of postsynapse	2/6463	23/18639	0.0869565217391304	0.250778679977666	0.999266619437378	1
GO:0008509	monoatomic anion transmembrane transporter activity	34/6463	149/18639	0.228187919463087	0.658083650142733	0.999405668354775	1
GO:0016874	ligase activity	39/6463	167/18639	0.233532934131737	0.673498430957982	0.999455857103587	1
GO:0004970	glutamate-gated receptor activity	1/6463	18/18639	0.0555555555555556	0.160219712207953	0.999532713976449	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	4/6463	36/18639	0.111111111111111	0.320439424415906	0.999724172993872	1
GO:0015464	acetylcholine receptor activity	1/6463	20/18639	0.05	0.144197740987158	0.999800800304354	1
GO:0030627	pre-mRNA 5'-splice site binding	1/6463	20/18639	0.05	0.144197740987158	0.999800800304354	1
GO:0015252	proton channel activity	2/6463	27/18639	0.0740740740740741	0.213626282943937	0.999845359735662	1
GO:0008236	serine-type peptidase activity	44/6463	194/18639	0.22680412371134	0.654092845714942	0.999902447789961	1
GO:0019825	oxygen binding	3/6463	34/18639	0.0882352941176471	0.254466601742043	0.999909591692746	1
GO:0017171	serine hydrolase activity	45/6463	198/18639	0.227272727272727	0.655444277214353	0.999910629437672	1
GO:0033038	bitter taste receptor activity	1/6463	22/18639	0.0454545454545455	0.131088855442871	0.99991509271634	1
GO:0071855	neuropeptide receptor binding	4/6463	40/18639	0.1	0.288395481974315	0.999931966949872	1
GO:0016917	GABA receptor activity	1/6463	23/18639	0.0434782608695652	0.125389339988833	0.999944568774475	1
GO:0001653	peptide receptor activity	25/6463	128/18639	0.1953125	0.563272425731085	0.999947368411109	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/6463	46/18639	0.108695652173913	0.313473349972082	0.999952357615328	1
GO:0004497	monooxygenase activity	19/6463	106/18639	0.179245283018868	0.51693529787849	0.999959025536413	1
GO:0004867	serine-type endopeptidase inhibitor activity	16/6463	95/18639	0.168421052631579	0.485718706483057	0.999967591903537	1
GO:0008188	neuropeptide receptor activity	5/6463	48/18639	0.104166666666667	0.300411960389912	0.999976007150495	1
GO:0008066	glutamate receptor activity	1/6463	26/18639	0.0384615384615385	0.110921339220891	0.999984579138391	1
GO:0008528	G protein-coupled peptide receptor activity	22/6463	122/18639	0.180327868852459	0.52005742651106	0.999985676315017	1
GO:0005261	monoatomic cation channel activity	83/6463	341/18639	0.243401759530792	0.701959677532791	0.999987690039161	1
GO:0004252	serine-type endopeptidase activity	36/6463	176/18639	0.204545454545455	0.589899849492918	0.999988623101317	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/6463	47/18639	0.0851063829787234	0.245442963382396	0.99999450344762	1
GO:0015370	solute:sodium symporter activity	10/6463	79/18639	0.126582278481013	0.365057572119387	0.999997883310026	1
GO:0022834	ligand-gated channel activity	37/6463	188/18639	0.196808510638298	0.567586852821791	0.999998110179564	1
GO:0005184	neuropeptide hormone activity	1/6463	31/18639	0.032258064516129	0.0930308006368759	0.999998172808771	1
GO:0015276	ligand-gated monoatomic ion channel activity	36/6463	186/18639	0.193548387096774	0.558184803821255	0.999998724564609	1
GO:0160041	neuropeptide activity	1/6463	32/18639	0.03125	0.0901235881169735	0.999998807435647	1
GO:0030280	structural constituent of skin epidermis	1/6463	37/18639	0.027027027027027	0.0779447248579231	0.999999858816291	1
GO:0022836	gated channel activity	69/6463	318/18639	0.216981132075472	0.625763781642382	0.999999870808539	1
GO:0005216	monoatomic ion channel activity	105/6463	448/18639	0.234375	0.675926910877302	0.99999993104623	1
GO:0005179	hormone activity	19/6463	132/18639	0.143939393939394	0.415114708902424	0.99999996166356	1
GO:0003823	antigen binding	28/6463	174/18639	0.160919540229885	0.464084683636829	0.999999988750158	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	5/6463	73/18639	0.0684931506849315	0.197531152037202	0.99999999710095	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/6463	69/18639	0.0579710144927536	0.167185786651777	0.999999998589051	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/6463	56/18639	0.0357142857142857	0.102998386419398	0.999999998697165	1
GO:0003730	mRNA 3'-UTR binding	47/6463	262/18639	0.179389312977099	0.517350673770718	0.999999999514508	1
GO:0030594	neurotransmitter receptor activity	8/6463	97/18639	0.0824742268041237	0.237851943896343	0.999999999811177	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/6463	53/18639	0.0188679245283019	0.0544142418819463	0.999999999847853	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/6463	63/18639	0.0158730158730159	0.0457770606308437	0.999999999997882	1
GO:0022835	transmitter-gated channel activity	1/6463	63/18639	0.0158730158730159	0.0457770606308437	0.999999999997882	1
GO:0003735	structural constituent of ribosome	7/6463	175/18639	0.04	0.115358192789726	1	1
GO:0030371	translation repressor activity	15/6463	329/18639	0.0455927051671733	0.131487301811998	1	1
GO:0045182	translation regulator activity	24/6463	356/18639	0.0674157303370786	0.194423920432123	1	1
GO:1903231	mRNA base-pairing translational repressor activity	3/6463	298/18639	0.0100671140939597	0.0290331022121794	1	1